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{{attachment:Software/EnrichmentMap/UserManual/enrichmentmap_logo3.png|Enrichment Map Logo|align="right"}}<
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= Enrichment Map Plugin Download Page =
== Brief Description ==
Enrichment Map is a Cytoscape plugin for functional enrichment visualization. Enrichment results have to be generated outside Enrichment Map, using any of the available methods. Gene-sets, such as pathways and Gene Ontology terms, are organized into a network (i.e. the "enrichment map"). In this way, mutually overlapping gene-sets cluster together, making interpretation easier. Enrichment Map also enables the comparison of two different enrichment results in the same map. 
Follow this link for [[Software/EnrichmentMap/Description|more details and an analysis example]]. 
== Plugin Download ==
Updated at 07/20/2010
 * [[attachment:EnrichmentMapPlugin_v1.00-RC7.zip|Enrichment Map Plugin (v1.00 Release Candidate 7)]]
Download the zipped file, move it to the Cytoscape plugin directory and unzip it.
== Sample Data Download ==
Standard analysis:
 * Estradiol-treated MCF7 breast cancer cells, 12hrs and 24hrs: [[attachment:EM_EstrogenMCF7_TestData.zip]]
 * [[Software/EnrichmentMap/Tutorial|Guided tutorial]] to load the test data into Enrichment Map
Post-analysis:
 * [[attachment:estrogenTargetsLin2007.GMT|Estrogen targets]] (Lin et al 2007, Plos Genetics)
== User Guide ==
[[Software/EnrichmentMap/UserManual|User Guide Link]]
== Gene-sets for Enrichment Analysis ==
 * we generate gene-set files for enrichment analysis (e.g. GSEA) by querying public resources such as Gene Ontology and KEGG, and using Entrez-Gene ID for genes
 [[GeneSetDB_02|download page]]
 * how to convert DAVID gene-sets to GMT: [[/DAVIDgs_R|R script]]
== Publications ==
 * Isserlin R, Merico D, Alikhani-Koupaei R, Gramolini A, Bader GD, Emili A. <
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 '''''Pathway analysis of dilated cardiomyopathy using global proteomic profiling and enrichment maps.''''' <
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 Proteomics. '''''2010''''' Feb 1. <
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 PMID: 20127684