1     M         1.839   1.856   1.908   2.047   2.074   2.155   2.015   2.038   2.120
2     S        -0.649  -0.558  -0.689  -0.597  -0.469  -0.642  -0.583  -0.471  -0.618
3     S        -0.829  -0.846  -0.791  -0.902  -0.931  -0.832  -0.791  -0.808  -0.733
4     T        -0.649  -0.622  -0.722  -0.547  -0.513  -0.670  -0.583  -0.548  -0.656
5     H        -1.749  -1.732  -1.637  -1.410  -1.380  -1.247  -1.232  -1.211  -1.100
6     S        -0.823  -0.835  -0.797  -0.987  -0.990  -0.934  -0.799  -0.804  -0.741
7     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    T        -0.243  -0.294  -0.237  -0.331  -0.474  -0.377  -0.421  -0.494  -0.418
25    E         0.713   0.597   0.628   0.667   0.484   0.520   0.554   0.337   0.364
26    Q        -0.937  -0.900  -0.835  -0.786  -0.738  -0.633  -0.908  -0.864  -0.778
27    Q        -0.243  -0.294  -0.237  -0.193  -0.259  -0.180  -0.421  -0.494  -0.418
28    R        -0.243  -0.256  -0.217  -0.306  -0.340  -0.291  -0.421  -0.445  -0.390
29    A         0.713   0.740   0.662   0.786   0.809   0.680   0.554   0.597   0.427
30    Q        -0.243  -0.294  -0.237  -0.402  -0.516  -0.434  -0.421  -0.494  -0.418
31    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    E        -0.243  -0.294  -0.237  -0.367  -0.448  -0.367  -0.421  -0.494  -0.418
38    N        -1.286  -1.303  -1.256  -1.154  -1.171  -1.105  -1.016  -1.025  -0.954
39    S        -0.649  -0.645  -0.750  -0.635  -0.630  -0.776  -0.583  -0.578  -0.687
40    L        -0.186  -0.216  -0.204  -0.392  -0.425  -0.378  -0.367  -0.392  -0.377
41    P        -0.649  -0.645  -0.750  -0.433  -0.430  -0.617  -0.583  -0.578  -0.687
42    K        -0.186  -0.216  -0.204  -0.135  -0.166  -0.146  -0.367  -0.392  -0.377
43    V         0.937   0.857   0.762   0.869   0.748   0.580   0.932   0.797   0.612
44    S        -0.186  -0.216  -0.177  -0.289  -0.314  -0.271  -0.367  -0.392  -0.346
45    Q        -0.186  -0.185  -0.185  -0.308  -0.304  -0.277  -0.367  -0.355  -0.351
46    S        -0.361  -0.346  -0.258  -0.732  -0.723  -0.578  -0.583  -0.562  -0.446
47    V        -0.823  -0.836  -0.768  -0.799  -0.808  -0.702  -0.799  -0.805  -0.714
48    Y        -0.361  -0.348  -0.265  -0.527  -0.515  -0.382  -0.583  -0.564  -0.455
49    Q        -0.649  -0.659  -0.699  -0.396  -0.417  -0.473  -0.583  -0.593  -0.630
50    M        -0.823  -0.814  -0.786  -0.653  -0.629  -0.600  -0.799  -0.783  -0.730
51    L         1.839   1.856   1.908   1.631   1.655   1.746   2.015   2.038   2.120
52    L         0.937   0.984   0.784   0.769   0.836   0.540   0.932   1.005   0.651
53    N        -0.649  -0.645  -0.750  -0.573  -0.564  -0.770  -0.583  -0.578  -0.687
54    E         1.839   1.856   1.908   1.841   1.868   1.953   2.015   2.038   2.120
55    M         0.564   0.574   0.598   0.305   0.320   0.368   0.283   0.295   0.307
56    V         1.839   1.856   1.908   1.756   1.783   1.868   2.015   2.038   2.120
57    P         1.839   1.856   1.908   1.977   1.999   2.086   2.015   2.038   2.120
58    L        -0.361  -0.341  -0.255  -0.529  -0.477  -0.337  -0.583  -0.555  -0.441
59    A         0.564   0.550   0.568   0.366   0.332   0.373   0.283   0.250   0.249
60    M        -0.186  -0.216  -0.204  -0.078  -0.095  -0.090  -0.367  -0.392  -0.377
61    G        -0.186  -0.155  -0.188  -0.110  -0.075  -0.106  -0.367  -0.327  -0.358
62    I         0.564   0.550   0.568   0.324   0.299   0.312   0.283   0.250   0.249
63    E        -0.186  -0.216  -0.204  -0.348  -0.374  -0.361  -0.367  -0.392  -0.377
64    R        -0.649  -0.556  -0.688  -0.410  -0.274  -0.460  -0.583  -0.469  -0.617
65    Q        -0.649  -0.610  -0.673  -0.467  -0.401  -0.516  -0.583  -0.533  -0.599
66    I        -0.186  -0.134  -0.151  -0.516  -0.431  -0.453  -0.367  -0.293  -0.304
67    S        -1.286  -1.265  -1.238  -1.290  -1.259  -1.207  -1.016  -0.991  -0.939
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    G        -0.829  -0.793  -0.772  -0.841  -0.784  -0.755  -0.791  -0.745  -0.711
73    D        -0.829  -0.842  -0.810  -0.753  -0.774  -0.720  -0.791  -0.801  -0.753
74    V        -0.829  -0.810  -0.795  -0.897  -0.868  -0.835  -0.791  -0.765  -0.736
75    I        -0.823  -0.771  -0.763  -0.986  -0.910  -0.887  -0.799  -0.741  -0.709
76    S        -0.649  -0.622  -0.682  -0.649  -0.622  -0.696  -0.583  -0.548  -0.611
77    S        -0.649  -0.558  -0.689  -0.618  -0.493  -0.668  -0.583  -0.471  -0.618
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    D        -0.186  -0.212  -0.185  -0.252  -0.300  -0.252  -0.367  -0.398  -0.356
80    S        -1.286  -1.251  -1.227  -1.255  -1.191  -1.171  -1.016  -0.976  -0.929
81    N        -1.286  -1.303  -1.256  -1.184  -1.209  -1.136  -1.016  -1.025  -0.954
82    V        -0.186  -0.164  -0.203  -0.422  -0.402  -0.437  -0.367  -0.343  -0.379
83    T         0.102   0.061  -0.062   0.237   0.178   0.004   0.066   0.007  -0.171
84    S        -0.823  -0.776  -0.763  -0.876  -0.817  -0.780  -0.799  -0.748  -0.709
85    E        -0.649  -0.659  -0.715  -0.599  -0.626  -0.759  -0.583  -0.593  -0.648
86    N        -1.286  -1.241  -1.216  -1.077  -1.021  -0.981  -1.016  -0.967  -0.919
87    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    I        -0.649  -0.659  -0.699  -0.519  -0.530  -0.597  -0.583  -0.593  -0.630
90    N        -0.186  -0.154  -0.159  -0.274  -0.225  -0.224  -0.367  -0.326  -0.319
91    N        -1.749  -1.732  -1.637  -1.535  -1.511  -1.369  -1.232  -1.211  -1.100
92    M        -1.749  -1.732  -1.637  -1.383  -1.362  -1.220  -1.232  -1.211  -1.100
93    I        -0.823  -0.836  -0.795  -1.039  -1.033  -0.968  -0.799  -0.806  -0.739
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   K        -1.286  -1.303  -1.256  -1.113  -1.122  -1.026  -1.016  -1.025  -0.954
109   R        -1.286  -1.264  -1.241  -1.213  -1.201  -1.157  -1.016  -0.990  -0.941
110   L        -1.286  -1.265  -1.238  -1.310  -1.296  -1.210  -1.016  -0.991  -0.939
111   K        -0.186  -0.215  -0.184  -0.262  -0.311  -0.266  -0.367  -0.403  -0.356
112   I        -1.286  -1.294  -1.255  -1.342  -1.354  -1.320  -1.016  -1.018  -0.953
113   E        -0.823  -0.812  -0.778  -0.816  -0.793  -0.734  -0.799  -0.781  -0.721
114   E        -0.823  -0.828  -0.781  -0.810  -0.811  -0.725  -0.799  -0.798  -0.724
115   H        -0.243  -0.308  -0.239  -0.103  -0.214  -0.105  -0.421  -0.510  -0.420
116   H         0.713   0.657   0.654   0.800   0.715   0.715   0.554   0.448   0.412
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   T         0.713   0.657   0.655   0.666   0.575   0.542   0.554   0.448   0.415
125   V        -0.064  -0.137  -0.142  -0.193  -0.309  -0.342  -0.167  -0.271  -0.285
126   D        -0.829  -0.791  -0.772  -0.806  -0.748  -0.729  -0.791  -0.745  -0.712
127   I        -0.829  -0.831  -0.773  -0.888  -0.893  -0.810  -0.791  -0.792  -0.713
128   I        -0.273  -0.254  -0.215  -0.652  -0.602  -0.534  -0.479  -0.449  -0.392
129   R        -1.286  -1.303  -1.256  -1.146  -1.186  -1.096  -1.016  -1.025  -0.954
130   S         0.937   0.857   0.762   0.916   0.804   0.680   0.932   0.797   0.612
131   H        -0.649  -0.645  -0.750  -0.250  -0.252  -0.430  -0.583  -0.578  -0.687
132   N        -0.649  -0.556  -0.688  -0.598  -0.439  -0.687  -0.583  -0.469  -0.617
133   L         0.102   0.061  -0.071   0.061   0.006  -0.154   0.066   0.007  -0.184
134   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   A        -0.243  -0.256  -0.217  -0.357  -0.406  -0.354  -0.421  -0.445  -0.390
141   D        -0.243  -0.294  -0.237  -0.417  -0.519  -0.442  -0.421  -0.494  -0.418
142   E         0.713   0.799   0.684   0.672   0.811   0.609   0.554   0.699   0.469
143   E         1.839   1.856   1.908   1.818   1.853   1.929   2.015   2.038   2.120
144   E        -1.286  -1.243  -1.217  -1.165  -1.104  -1.060  -1.016  -0.968  -0.920
145   K        -0.823  -0.775  -0.771  -0.809  -0.734  -0.729  -0.799  -0.747  -0.716
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   E        -0.186  -0.156  -0.188  -0.288  -0.244  -0.284  -0.367  -0.328  -0.359
148   K        -1.286  -1.265  -1.238  -1.204  -1.161  -1.141  -1.016  -0.991  -0.939
149   V         1.839   1.856   1.908   1.756   1.783   1.868   2.015   2.038   2.120
150   L        -0.649  -0.659  -0.715  -0.491  -0.509  -0.618  -0.583  -0.593  -0.648
151   A        -0.823  -0.775  -0.773  -0.869  -0.794  -0.796  -0.799  -0.747  -0.718
152   R         1.839   1.856   1.908   1.961   1.982   2.070   2.015   2.038   2.120
153   L        -0.186  -0.129  -0.159  -0.544  -0.450  -0.481  -0.367  -0.285  -0.315
154   R        -0.649  -0.622  -0.722  -0.458  -0.415  -0.551  -0.583  -0.548  -0.656
155   N        -0.649  -0.693  -0.717  -0.538  -0.602  -0.665  -0.583  -0.633  -0.650
156   I        -0.823  -0.836  -0.795  -0.848  -0.882  -0.841  -0.799  -0.806  -0.739
157   G         1.839   1.856   1.908   1.926   1.946   2.035   2.015   2.038   2.120
158   F        -0.186  -0.212  -0.185  -0.145  -0.186  -0.148  -0.367  -0.398  -0.356
159   Q        -1.286  -1.294  -1.255  -1.132  -1.139  -1.101  -1.016  -1.018  -0.953
160   I         0.102   0.076  -0.072   0.114   0.078  -0.204   0.066   0.027  -0.186
161   G         1.839   1.856   1.908   1.926   1.946   2.035   2.015   2.038   2.120
162   L        -0.186  -0.239  -0.187  -0.531  -0.601  -0.505  -0.367  -0.427  -0.356
163   K         0.102   0.061  -0.071   0.267   0.208   0.012   0.066   0.007  -0.184
164   L        -0.186  -0.179  -0.178  -0.427  -0.401  -0.374  -0.367  -0.346  -0.341
165   S        -1.286  -1.295  -1.222  -1.157  -1.189  -1.045  -1.016  -1.019  -0.924
166   E         1.839   1.856   1.908   1.841   1.868   1.953   2.015   2.038   2.120
167   L         0.837   0.849   0.715   0.617   0.634   0.414   0.768   0.784   0.525
168   L         0.837   0.847   0.716   0.634   0.647   0.443   0.768   0.780   0.528
169   I        -1.286  -1.265  -1.238  -1.233  -1.184  -1.167  -1.016  -0.991  -0.939
170   F         0.937   1.002   0.789   1.133   1.219   0.937   0.932   1.034   0.659
171   S         0.564   0.616   0.613   0.316   0.401   0.390   0.283   0.372   0.336
172   N        -0.186  -0.216  -0.204  -0.296  -0.320  -0.310  -0.367  -0.392  -0.377
173   N        -0.186  -0.216  -0.204  -0.327  -0.357  -0.355  -0.367  -0.392  -0.377
174   P        -0.649  -0.645  -0.750  -0.389  -0.388  -0.557  -0.583  -0.578  -0.687
175   N        -0.649  -0.659  -0.699  -0.441  -0.453  -0.514  -0.583  -0.593  -0.630
176   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   K        -0.186  -0.216  -0.186  -0.197  -0.239  -0.189  -0.367  -0.404  -0.359
180   E        -1.749  -1.732  -1.637  -1.622  -1.592  -1.455  -1.232  -1.211  -1.100
181   M        -0.186  -0.216  -0.204  -0.171  -0.196  -0.205  -0.367  -0.392  -0.377
182   D         1.839   1.856   1.908   1.854   1.879   1.964   2.015   2.038   2.120
183   L        -0.361  -0.341  -0.255  -0.656  -0.604  -0.466  -0.583  -0.555  -0.441
184   L         1.839   1.856   1.908   1.631   1.655   1.746   2.015   2.038   2.120
185   L        -0.649  -0.622  -0.722  -0.573  -0.532  -0.704  -0.583  -0.548  -0.656
186   I        -0.186  -0.216  -0.186  -0.295  -0.337  -0.285  -0.367  -0.404  -0.359
187   M         0.102   0.001  -0.078   0.360   0.204   0.045   0.066  -0.075  -0.195
188   K         0.937   0.912   0.779   1.060   1.033   0.840   0.932   0.888   0.642
189   F         1.839   1.856   1.908   1.937   1.961   2.047   2.015   2.038   2.120
190   I        -0.186  -0.238  -0.186  -0.443  -0.526  -0.453  -0.367  -0.426  -0.355
191   C         1.839   1.856   1.908   2.140   2.165   2.246   2.015   2.038   2.120
192   R         0.564   0.525   0.560   0.527   0.445   0.486   0.283   0.202   0.234
193   D         0.937   0.912   0.779   1.009   0.976   0.774   0.932   0.888   0.642
194   V         0.937   0.857   0.762   0.869   0.748   0.580   0.932   0.797   0.612
195   W         1.839   1.856   1.908   2.162   2.188   2.268   2.015   2.038   2.120
196   K         0.102   0.061  -0.071   0.270   0.213   0.016   0.066   0.007  -0.184
197   Q        -0.823  -0.770  -0.776  -0.897  -0.846  -0.820  -0.799  -0.740  -0.720
198   I        -0.186  -0.168  -0.183  -0.544  -0.523  -0.525  -0.367  -0.349  -0.355
199   F         0.564   0.550   0.568   0.634   0.603   0.607   0.283   0.250   0.249
200   G         0.102   0.076  -0.072   0.301   0.260   0.036   0.066   0.027  -0.186
201   K         1.839   1.856   1.908   1.882   1.911   1.992   2.015   2.038   2.120
202   Q         1.839   1.856   1.908   1.941   1.968   2.051   2.015   2.038   2.120
203   I        -0.186  -0.216  -0.204  -0.213  -0.252  -0.245  -0.367  -0.392  -0.377
204   D         0.937   0.984   0.784   0.987   1.055   0.747   0.932   1.005   0.651
205   N         1.839   1.856   1.908   1.894   1.922   2.004   2.015   2.038   2.120
206   L         1.839   1.856   1.908   1.631   1.655   1.746   2.015   2.038   2.120
207   K         0.564   0.616   0.613   0.491   0.579   0.563   0.283   0.372   0.336
208   T         1.839   1.856   1.908   1.937   1.962   2.047   2.015   2.038   2.120
209   N         1.839   1.856   1.908   1.894   1.922   2.004   2.015   2.038   2.120
210   H         1.839   1.856   1.908   2.113   2.141   2.219   2.015   2.038   2.120
211   R         1.839   1.856   1.908   1.961   1.982   2.070   2.015   2.038   2.120
212   G         1.839   1.856   1.908   1.926   1.946   2.035   2.015   2.038   2.120
213   T         0.564   0.525   0.560   0.449   0.360   0.392   0.283   0.202   0.234
214   F         0.937   0.857   0.762   1.133   1.027   0.896   0.932   0.797   0.612
215   Y         0.451   0.465   0.538   0.271   0.292   0.402   0.066   0.085   0.191
216   L         1.839   1.856   1.908   1.631   1.655   1.746   2.015   2.038   2.120
217   L        -0.823  -0.865  -0.806  -1.042  -1.083  -0.970  -0.799  -0.832  -0.750
218   D         1.839   1.856   1.908   1.854   1.879   1.964   2.015   2.038   2.120
219   Y         0.451   0.465   0.538   0.369   0.391   0.502   0.066   0.085   0.191
220   D        -0.823  -0.805  -0.781  -0.952  -0.931  -0.879  -0.799  -0.775  -0.725
221   Y         0.564   0.525   0.560   0.634   0.554   0.591   0.283   0.202   0.234
222   R        -0.186  -0.215  -0.185  -0.184  -0.224  -0.170  -0.367  -0.403  -0.357
223   P         0.564   0.616   0.613   0.431   0.529   0.486   0.283   0.372   0.336
224   I         0.937   0.857   0.762   0.963   0.847   0.671   0.932   0.797   0.612
225   Q        -0.186  -0.164  -0.203  -0.289  -0.268  -0.337  -0.367  -0.343  -0.379
226   S        -0.823  -0.865  -0.769  -0.849  -0.898  -0.753  -0.799  -0.832  -0.715
227   F        -0.186  -0.156  -0.201  -0.173  -0.127  -0.211  -0.367  -0.335  -0.378
228   S        -0.823  -0.775  -0.773  -0.786  -0.735  -0.701  -0.799  -0.747  -0.718
229   L        -0.186  -0.216  -0.204  -0.517  -0.547  -0.506  -0.367  -0.392  -0.377
230   E        -0.186  -0.156  -0.177  -0.334  -0.296  -0.329  -0.367  -0.335  -0.347
231   E        -1.286  -1.303  -1.256  -1.263  -1.279  -1.239  -1.016  -1.025  -0.954
232   D        -0.186  -0.216  -0.204  -0.286  -0.333  -0.324  -0.367  -0.392  -0.377
233   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   K        -1.749  -1.732  -1.637  -1.495  -1.497  -1.330  -1.232  -1.211  -1.100
237   N        -0.829  -0.810  -0.795  -0.810  -0.780  -0.754  -0.791  -0.765  -0.736
238   E        -0.823  -0.835  -0.778  -0.834  -0.838  -0.754  -0.799  -0.804  -0.723
239   E        -0.823  -0.865  -0.806  -0.855  -0.918  -0.835  -0.799  -0.832  -0.750
240   L         0.102   0.061  -0.071  -0.050  -0.110  -0.321   0.066   0.007  -0.184
241   K        -0.823  -0.836  -0.782  -0.880  -0.893  -0.801  -0.799  -0.806  -0.725
242   M        -1.286  -1.303  -1.256  -1.135  -1.151  -1.090  -1.016  -1.025  -0.954
243   I        -0.823  -0.784  -0.780  -0.752  -0.702  -0.659  -0.799  -0.755  -0.725
244   E        -0.823  -0.865  -0.806  -0.876  -0.929  -0.847  -0.799  -0.832  -0.750
245   P         0.102   0.187  -0.064   0.302   0.429   0.023   0.066   0.187  -0.175
246   F         0.451   0.465   0.537   0.399   0.419   0.534   0.066   0.086   0.188
247   L         0.937   0.912   0.779   0.788   0.756   0.564   0.932   0.888   0.642
248   E        -0.186  -0.185  -0.185  -0.016   0.002  -0.012  -0.367  -0.355  -0.351
249   I        -0.186  -0.185  -0.185  -0.251  -0.238  -0.255  -0.367  -0.355  -0.351
250   P         1.839   1.856   1.908   1.977   1.999   2.086   2.015   2.038   2.120
251   V        -0.186  -0.185  -0.185  -0.162  -0.148  -0.188  -0.367  -0.355  -0.351
252   G         1.839   1.856   1.908   1.926   1.946   2.035   2.015   2.038   2.120
253   I         0.564   0.606   0.627   0.324   0.399   0.421   0.283   0.354   0.362
254   I         0.937   0.857   0.762   0.988   0.877   0.713   0.932   0.797   0.612
255   R         0.102   0.106  -0.045   0.278   0.278   0.030   0.066   0.072  -0.148
256   G         1.839   1.856   1.908   1.926   1.946   2.035   2.015   2.038   2.120
257   V        -0.186  -0.221  -0.180  -0.313  -0.345  -0.278  -0.367  -0.400  -0.343
258   L         1.839   1.856   1.908   1.631   1.655   1.746   2.015   2.038   2.120
259   S        -0.823  -0.865  -0.806  -0.749  -0.804  -0.700  -0.799  -0.832  -0.750
260   S         0.937   0.857   0.762   0.916   0.804   0.680   0.932   0.797   0.612
261   L        -0.186  -0.216  -0.204  -0.375  -0.402  -0.353  -0.367  -0.392  -0.377
262   G         1.839   1.856   1.908   1.926   1.946   2.035   2.015   2.038   2.120
263   Y        -0.649  -0.622  -0.722  -0.514  -0.473  -0.626  -0.583  -0.548  -0.656
264   S        -0.823  -0.835  -0.797  -0.810  -0.818  -0.768  -0.799  -0.804  -0.741
265   S        -0.649  -0.622  -0.722  -0.479  -0.444  -0.632  -0.583  -0.548  -0.656
266   E        -0.823  -0.828  -0.777  -0.841  -0.840  -0.756  -0.799  -0.798  -0.721
267   E        -0.186  -0.185  -0.185  -0.383  -0.371  -0.368  -0.367  -0.355  -0.351
268   V        -1.286  -1.294  -1.255  -1.213  -1.216  -1.146  -1.016  -1.018  -0.953
269   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   R        -0.186  -0.185  -0.185  -0.115  -0.114  -0.109  -0.367  -0.355  -0.351
284   P         0.451   0.465   0.538   0.277   0.295   0.413   0.066   0.085   0.191
285   K        -1.286  -1.265  -1.220  -1.302  -1.281  -1.200  -1.016  -0.991  -0.923
286   T        -0.823  -0.812  -0.764  -0.862  -0.855  -0.763  -0.799  -0.781  -0.710
287   A        -0.649  -0.659  -0.715  -0.517  -0.538  -0.652  -0.583  -0.593  -0.648
288   F         0.937   0.857   0.762   1.052   0.926   0.755   0.932   0.797   0.612
289   P         1.839   1.856   1.908   1.977   1.999   2.086   2.015   2.038   2.120
290   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   G        -0.186  -0.164  -0.203  -0.192  -0.172  -0.227  -0.367  -0.343  -0.379
292   V         0.102   0.001  -0.078   0.078  -0.074  -0.212   0.066  -0.075  -0.195
293   S        -0.823  -0.814  -0.786  -0.987  -0.970  -0.900  -0.799  -0.783  -0.730
294   F         1.839   1.856   1.908   1.937   1.961   2.047   2.015   2.038   2.120
295   H        -0.186  -0.221  -0.180  -0.089  -0.130  -0.067  -0.367  -0.400  -0.343
296   V         0.564   0.606   0.627   0.367   0.450   0.460   0.283   0.354   0.362
297   Q         0.102   0.076  -0.072   0.351   0.309   0.101   0.066   0.027  -0.186
298   V         0.451   0.465   0.538   0.187   0.209   0.334   0.066   0.085   0.191
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   T        -1.384  -1.364  -1.276  -1.377  -1.328  -1.214  -1.103  -1.078  -0.971
301   M        -0.829  -0.869  -0.811  -0.723  -0.774  -0.682  -0.791  -0.831  -0.754
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   P        -0.823  -0.778  -0.777  -0.709  -0.640  -0.618  -0.799  -0.748  -0.720
307   Q        -0.649  -0.622  -0.722  -0.472  -0.431  -0.588  -0.583  -0.548  -0.656
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q99394
Output conservation file - output/Q99394
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
