1     M         1.430   1.446   1.524   1.627   1.659   1.769   1.541   1.566   1.676
2     G        -1.145  -1.180  -1.058  -1.310  -1.386  -1.199  -1.064  -1.086  -0.925
3     K        -1.163  -1.166  -1.063  -1.329  -1.341  -1.167  -1.072  -1.070  -0.929
4     T        -1.163  -1.125  -1.051  -1.073  -1.021  -0.893  -1.072  -1.031  -0.917
5     A        -0.783  -0.742  -0.693  -0.714  -0.642  -0.588  -0.878  -0.827  -0.750
6     D        -1.244  -1.225  -1.086  -1.267  -1.233  -1.029  -1.147  -1.123  -0.948
7     N        -0.783  -0.742  -0.693  -0.891  -0.827  -0.757  -0.878  -0.827  -0.750
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    G        -1.244  -1.225  -1.086  -1.469  -1.445  -1.225  -1.147  -1.123  -0.948
20    P        -0.783  -0.785  -0.693  -0.848  -0.851  -0.738  -0.878  -0.877  -0.751
21    V        -0.779  -0.743  -0.688  -0.858  -0.794  -0.731  -0.885  -0.843  -0.748
22    R        -0.239  -0.172  -0.187  -0.549  -0.449  -0.446  -0.516  -0.442  -0.424
23    S         0.749   0.807   0.600   0.762   0.838   0.558   0.718   0.808   0.423
24    E        -0.487  -0.395  -0.580  -0.218  -0.069  -0.399  -0.516  -0.401  -0.619
25    T        -0.158  -0.154  -0.168  -0.314  -0.307  -0.384  -0.379  -0.372  -0.391
26    A         0.295   0.299   0.400  -0.023  -0.031   0.138  -0.105  -0.107   0.037
27    R         1.430   1.446   1.524   1.387   1.422   1.537   1.541   1.566   1.676
28    E        -0.487  -0.428  -0.581  -0.628  -0.545  -0.758  -0.516  -0.446  -0.621
29    G         1.430   1.446   1.524   1.477   1.503   1.623   1.541   1.566   1.676
30    R         1.430   1.446   1.524   1.387   1.422   1.537   1.541   1.566   1.676
31    E        -0.692  -0.662  -0.663  -0.917  -0.864  -0.838  -0.790  -0.766  -0.722
32    N         0.436   0.388   0.433   0.369   0.277   0.291   0.170   0.069   0.102
33    Q         0.749   0.695   0.581   1.013   0.950   0.765   0.718   0.628   0.389
34    V        -0.239  -0.187  -0.192  -0.424  -0.351  -0.340  -0.516  -0.450  -0.428
35    Y         0.749   0.695   0.581   1.027   0.970   0.794   0.718   0.628   0.389
36    S        -0.239  -0.165  -0.192  -0.365  -0.251  -0.262  -0.516  -0.430  -0.428
37    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    V        -1.145  -1.179  -1.056  -1.282  -1.322  -1.124  -1.064  -1.085  -0.924
39    T        -0.487  -0.475  -0.592  -0.365  -0.359  -0.573  -0.516  -0.504  -0.634
40    G         1.430   1.446   1.524   1.477   1.503   1.623   1.541   1.566   1.676
41    A         0.107   0.048  -0.096   0.086  -0.015  -0.280   0.032  -0.054  -0.277
42    R         1.430   1.446   1.524   1.387   1.422   1.537   1.541   1.566   1.676
43    L         0.107   0.088  -0.093   0.187   0.160  -0.107   0.032   0.004  -0.274
44    V         0.749   0.695   0.581   0.835   0.763   0.574   0.718   0.628   0.389
45    A         1.430   1.446   1.524   1.391   1.416   1.541   1.541   1.566   1.676
46    G         1.430   1.446   1.524   1.477   1.503   1.623   1.541   1.566   1.676
47    C         0.436   0.388   0.433   0.567   0.473   0.500   0.170   0.069   0.102
48    I        -0.158  -0.110  -0.152  -0.126  -0.038  -0.096  -0.379  -0.298  -0.365
49    C        -0.487  -0.541  -0.626  -0.139  -0.226  -0.398  -0.516  -0.585  -0.674
50    L         0.208   0.250  -0.048   0.335   0.362  -0.005   0.176   0.235  -0.207
51    T        -0.765  -0.731  -0.692  -0.768  -0.688  -0.660  -0.874  -0.839  -0.753
52    P        -1.053  -0.957  -1.003  -1.175  -1.006  -1.079  -0.979  -0.879  -0.877
53    D        -0.066   0.012  -0.125  -0.016   0.102  -0.117  -0.244  -0.129  -0.325
54    K        -0.066  -0.020  -0.118  -0.267  -0.197  -0.346  -0.244  -0.166  -0.315
55    K        -1.737  -1.727  -1.620  -1.607  -1.593  -1.457  -1.294  -1.280  -1.128
56    Q        -1.053  -1.025  -1.021  -0.911  -0.879  -0.801  -0.979  -0.947  -0.893
57    V         0.804   0.848   0.630   0.929   1.024   0.699   0.806   0.872   0.480
58    L        -0.066  -0.092  -0.153  -0.055  -0.105  -0.154  -0.244  -0.265  -0.366
59    M         0.496   0.414   0.450   0.602   0.461   0.462   0.281   0.120   0.137
60    I         0.496   0.474   0.460   0.523   0.486   0.427   0.281   0.233   0.157
61    T        -0.585  -0.516  -0.621  -0.536  -0.420  -0.566  -0.664  -0.595  -0.676
62    S         1.430   1.446   1.524   1.384   1.436   1.533   1.541   1.566   1.676
63    S        -0.297  -0.333  -0.245  -0.487  -0.511  -0.416  -0.559  -0.612  -0.494
64    A        -0.066  -0.157  -0.164  -0.202  -0.337  -0.396  -0.244  -0.370  -0.386
65    H        -0.354  -0.433  -0.588  -0.005  -0.135  -0.420  -0.349  -0.455  -0.629
66    K        -0.354  -0.373  -0.564  -0.305  -0.353  -0.574  -0.349  -0.378  -0.600
67    K        -0.158  -0.207  -0.184  -0.203  -0.237  -0.262  -0.379  -0.432  -0.411
68    R        -0.354  -0.433  -0.588  -0.279  -0.337  -0.673  -0.349  -0.455  -0.629
69    W         1.430   1.446   1.524   1.636   1.646   1.778   1.541   1.566   1.676
70    I         0.278   0.300   0.404   0.107   0.161   0.306  -0.139  -0.105   0.045
71    V        -0.189  -0.139  -0.170  -0.297  -0.250  -0.223  -0.454  -0.396  -0.403
72    P         1.430   1.446   1.524   1.529   1.539   1.674   1.541   1.566   1.676
73    K         1.430   1.446   1.524   1.284   1.279   1.437   1.541   1.566   1.676
74    G         1.430   1.446   1.524   1.481   1.566   1.627   1.541   1.566   1.676
75    G         1.430   1.446   1.524   1.481   1.566   1.627   1.541   1.566   1.676
76    V        -0.765  -0.750  -0.685  -0.671  -0.637  -0.537  -0.874  -0.861  -0.746
77    E         1.430   1.446   1.524   1.197   1.182   1.353   1.541   1.566   1.676
78    K        -1.053  -1.022  -1.026  -1.163  -1.160  -1.118  -0.979  -0.945  -0.897
79    D         1.430   1.446   1.524   1.498   1.509   1.644   1.541   1.566   1.676
80    E         1.430   1.446   1.524   1.197   1.182   1.353   1.541   1.566   1.676
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    P        -0.149  -0.225  -0.205  -0.092  -0.228  -0.218  -0.340  -0.454  -0.436
86    N        -0.585  -0.615  -0.630  -0.589  -0.679  -0.692  -0.664  -0.704  -0.687
87    Y        -1.053  -1.091  -1.025  -0.778  -0.807  -0.755  -0.979  -1.004  -0.895
88    E        -1.737  -1.731  -1.617  -1.734  -1.690  -1.513  -1.294  -1.282  -1.127
89    T        -1.053  -0.962  -1.004  -1.109  -1.000  -1.006  -0.979  -0.891  -0.878
90    T        -0.368  -0.335  -0.247  -0.587  -0.499  -0.407  -0.664  -0.617  -0.497
91    A         1.430   1.446   1.524   1.394   1.444   1.544   1.541   1.566   1.676
92    Q        -1.449  -1.402  -1.343  -1.344  -1.265  -1.174  -1.189  -1.147  -1.031
93    R         1.430   1.446   1.524   1.401   1.478   1.550   1.541   1.566   1.676
94    E         1.430   1.446   1.524   1.197   1.182   1.353   1.541   1.566   1.676
95    T         0.208   0.054  -0.083   0.413   0.244  -0.034   0.176  -0.044  -0.258
96    W         1.430   1.446   1.524   1.636   1.646   1.778   1.541   1.566   1.676
97    E         1.430   1.446   1.524   1.197   1.182   1.353   1.541   1.566   1.676
98    E         1.430   1.446   1.524   1.197   1.182   1.353   1.541   1.566   1.676
99    A         0.804   0.728   0.608   0.843   0.781   0.575   0.806   0.682   0.438
100   G         1.430   1.446   1.524   1.481   1.566   1.627   1.541   1.566   1.676
101   C        -1.053  -1.115  -1.027  -0.823  -0.902  -0.817  -0.979  -1.030  -0.899
102   I        -0.765  -0.725  -0.690  -0.896  -0.820  -0.770  -0.874  -0.837  -0.750
103   G         0.804   0.724   0.602   0.928   0.892   0.643   0.806   0.675   0.427
104   K        -1.341  -1.353  -1.320  -1.252  -1.278  -1.189  -1.084  -1.094  -1.010
105   I         1.430   1.446   1.524   1.525   1.543   1.670   1.541   1.566   1.676
106   V        -1.341  -1.389  -1.344  -1.128  -1.152  -1.147  -1.084  -1.124  -1.029
107   A        -1.341  -1.323  -1.320  -1.308  -1.261  -1.259  -1.084  -1.068  -1.009
108   N        -1.449  -1.436  -1.352  -1.445  -1.402  -1.255  -1.189  -1.170  -1.037
109   L         1.430   1.446   1.524   1.405   1.392   1.554   1.541   1.566   1.676
110   G         0.496   0.557   0.494   0.498   0.645   0.477   0.281   0.386   0.222
111   T        -1.449  -1.425  -1.344  -1.398  -1.354  -1.235  -1.189  -1.162  -1.031
112   V        -1.053  -1.078  -1.029  -0.874  -0.875  -0.811  -0.979  -1.001  -0.900
113   E        -1.161  -1.178  -1.059  -1.406  -1.474  -1.198  -1.084  -1.086  -0.927
114   D         1.430   1.446   1.524   1.498   1.509   1.644   1.541   1.566   1.676
115   M        -0.585  -0.670  -0.657  -0.455  -0.541  -0.611  -0.664  -0.747  -0.712
116   R         1.430   1.446   1.524   1.401   1.478   1.550   1.541   1.566   1.676
117   P        -0.066  -0.029  -0.140  -0.020   0.040  -0.168  -0.244  -0.182  -0.347
118   P        -0.354  -0.349  -0.577  -0.144  -0.148  -0.526  -0.349  -0.347  -0.615
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   K         0.208   0.230  -0.032   0.226   0.224  -0.070   0.176   0.207  -0.183
135   D        -1.053  -1.126  -1.035  -1.174  -1.325  -1.194  -0.979  -1.036  -0.905
136   W        -1.449  -1.469  -1.360  -1.191  -1.221  -1.076  -1.189  -1.196  -1.043
137   N        -1.737  -1.731  -1.617  -1.479  -1.435  -1.321  -1.294  -1.282  -1.127
138   K        -1.737  -1.687  -1.606  -1.510  -1.470  -1.310  -1.294  -1.250  -1.119
139   D        -0.585  -0.573  -0.638  -0.672  -0.709  -0.825  -0.664  -0.657  -0.695
140   I        -1.474  -1.452  -1.360  -1.593  -1.633  -1.440  -1.201  -1.180  -1.041
141   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   R        -0.783  -0.647  -0.682  -0.945  -0.650  -0.813  -0.878  -0.713  -0.738
148   K        -1.163  -1.154  -1.058  -1.295  -1.271  -1.124  -1.072  -1.061  -0.923
149   D         0.278   0.302   0.404  -0.104  -0.116   0.089  -0.139  -0.101   0.044
150   S        -0.779  -0.735  -0.693  -0.899  -0.822  -0.805  -0.885  -0.836  -0.753
151   E        -0.011   0.019  -0.121  -0.172  -0.154  -0.318  -0.139  -0.096  -0.315
152   V        -0.250  -0.309  -0.223  -0.364  -0.478  -0.346  -0.512  -0.584  -0.464
153   A        -1.163  -1.166  -1.067  -1.154  -1.146  -1.036  -1.072  -1.071  -0.932
154   K        -0.634  -0.687  -0.677  -0.754  -0.888  -0.817  -0.699  -0.764  -0.732
155   H        -1.547  -1.513  -1.381  -1.332  -1.288  -1.093  -1.259  -1.224  -1.057
156   P        -0.585  -0.607  -0.639  -0.484  -0.551  -0.584  -0.664  -0.683  -0.695
157   P         0.804   0.724   0.602   0.938   0.801   0.602   0.806   0.675   0.427
158   R         0.331   0.362   0.423   0.010   0.097   0.140  -0.034   0.019   0.083
159   T        -0.066  -0.108  -0.146  -0.122  -0.138  -0.244  -0.244  -0.291  -0.357
160   E         0.804   0.724   0.602   0.634   0.479   0.354   0.806   0.675   0.427
161   F         0.208   0.054  -0.083   0.582   0.394   0.197   0.176  -0.044  -0.258
162   H         0.208   0.054  -0.083   0.510   0.279  -0.001   0.176  -0.044  -0.258
163   F         1.430   1.446   1.524   1.623   1.645   1.765   1.541   1.566   1.676
164   Y         0.278   0.302   0.402   0.287   0.331   0.477  -0.139  -0.102   0.040
165   E         1.430   1.446   1.524   1.197   1.182   1.353   1.541   1.566   1.676
166   L        -0.656  -0.736  -0.650  -0.618  -0.705  -0.592  -0.769  -0.837  -0.710
167   E        -1.053  -1.036  -1.023  -1.010  -0.989  -0.942  -0.979  -0.957  -0.894
168   I        -0.066   0.039  -0.111  -0.007   0.194  -0.060  -0.244  -0.085  -0.305
169   E        -1.053  -1.014  -1.015  -1.164  -1.129  -1.067  -0.979  -0.935  -0.886
170   N        -1.053  -1.110  -1.024  -1.078  -1.135  -1.004  -0.979  -1.025  -0.896
171   L         0.804   0.724   0.602   0.813   0.653   0.484   0.806   0.675   0.427
172   L        -0.585  -0.511  -0.621  -0.863  -0.784  -0.900  -0.664  -0.568  -0.672
173   D        -0.354  -0.353  -0.585  -0.127  -0.139  -0.483  -0.349  -0.351  -0.626
174   K        -1.053  -1.059  -1.021  -1.108  -1.089  -1.100  -0.979  -0.973  -0.893
175   F        -0.297  -0.256  -0.220  -0.135  -0.084  -0.029  -0.559  -0.503  -0.458
176   P         1.430   1.446   1.524   1.529   1.539   1.674   1.541   1.566   1.676
177   E         1.430   1.446   1.524   1.197   1.182   1.353   1.541   1.566   1.676
178   C        -1.021  -0.999  -1.011  -0.758  -0.717  -0.786  -0.927  -0.905  -0.880
179   H        -0.692  -0.754  -0.670  -0.739  -0.866  -0.689  -0.790  -0.845  -0.727
180   K         0.208   0.230  -0.036   0.209   0.222  -0.107   0.176   0.207  -0.189
181   R         1.430   1.446   1.524   1.401   1.478   1.550   1.541   1.566   1.676
182   H        -1.737  -1.727  -1.620  -1.489  -1.533  -1.361  -1.294  -1.280  -1.128
183   R         1.430   1.446   1.524   1.401   1.478   1.550   1.541   1.566   1.676
184   K        -0.066   0.012  -0.125  -0.216  -0.110  -0.268  -0.244  -0.129  -0.325
185   L         0.496   0.588   0.513   0.609   0.734   0.599   0.281   0.441   0.258
186   Y        -1.161  -1.176  -1.056  -0.825  -0.802  -0.675  -1.084  -1.084  -0.924
187   S        -0.189  -0.189  -0.176  -0.286  -0.236  -0.249  -0.454  -0.451  -0.409
188   Y         0.804   0.799   0.617   1.097   1.114   0.852   0.806   0.797   0.456
189   T        -1.449  -1.442  -1.356  -1.547  -1.502  -1.366  -1.189  -1.177  -1.039
190   E         0.804   0.848   0.628   0.669   0.688   0.472   0.806   0.873   0.476
191   A         1.430   1.446   1.524   1.394   1.444   1.544   1.541   1.566   1.676
192   K         0.804   0.724   0.602   0.739   0.614   0.476   0.806   0.675   0.427
193   Q        -0.765  -0.706  -0.675  -0.851  -0.821  -0.705  -0.874  -0.795  -0.733
194   N        -1.053  -1.128  -1.046  -1.088  -1.206  -1.095  -0.979  -1.038  -0.914
195   L         1.430   1.446   1.524   1.405   1.392   1.554   1.541   1.566   1.676
196   I        -0.779  -0.726  -0.697  -0.810  -0.733  -0.676  -0.885  -0.827  -0.757
197   D        -0.634  -0.570  -0.667  -0.872  -0.801  -0.950  -0.699  -0.618  -0.722
198   A        -0.354  -0.466  -0.582  -0.278  -0.427  -0.654  -0.349  -0.492  -0.622
199   K         0.208   0.054  -0.083   0.125  -0.144  -0.356   0.176  -0.044  -0.258
200   R         1.430   1.446   1.524   1.401   1.478   1.550   1.541   1.566   1.676
201   P         0.208   0.121  -0.061   0.390   0.231  -0.051   0.176   0.051  -0.226
202   E         0.804   0.728   0.608   0.648   0.508   0.395   0.806   0.682   0.438
203   L         0.804   0.728   0.608   0.860   0.725   0.599   0.806   0.682   0.438
204   L        -0.765  -0.781  -0.686  -0.792  -0.810  -0.638  -0.874  -0.879  -0.746
205   E        -0.066  -0.106  -0.160  -0.332  -0.453  -0.454  -0.244  -0.328  -0.379
206   A         1.430   1.446   1.524   1.394   1.444   1.544   1.541   1.566   1.676
207   L         1.430   1.446   1.524   1.405   1.392   1.554   1.541   1.566   1.676
208   N        -1.053  -1.066  -1.022  -1.002  -1.052  -0.997  -0.979  -0.990  -0.895
209   R        -1.341  -1.389  -1.344  -1.197  -1.276  -1.202  -1.084  -1.124  -1.029
210   S         1.430   1.446   1.524   1.384   1.436   1.533   1.541   1.566   1.676
211   A        -0.354  -0.326  -0.561  -0.206  -0.135  -0.483  -0.349  -0.319  -0.596
212   I         0.804   0.799   0.617   0.963   0.946   0.690   0.806   0.797   0.456
213   I        -0.011   0.019  -0.121   0.040   0.065  -0.184  -0.139  -0.096  -0.315
214   K         1.430   1.446   1.524   1.298   1.266   1.451   1.541   1.566   1.676
215   D        -0.011  -0.086  -0.152   0.009  -0.157  -0.294  -0.139  -0.255  -0.360
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   D        -0.779  -0.736  -0.676  -1.144  -1.141  -0.951  -0.885  -0.838  -0.736
227   K        -0.779  -0.781  -0.687  -0.813  -0.774  -0.695  -0.885  -0.879  -0.746
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q99321
Output conservation file - output/Q99321
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
