1     M         1.691   1.705   1.779   1.910   1.926   2.037   1.825   1.847   1.960
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -0.709  -0.717  -0.617  -0.929  -0.986  -0.826  -0.781  -0.793  -0.669
6     P        -0.806  -0.736  -0.875  -0.679  -0.578  -0.803  -0.663  -0.586  -0.722
7     I         0.069   0.024  -0.030  -0.031  -0.161  -0.262  -0.098  -0.186  -0.254
8     T        -1.001  -1.014  -0.963  -0.860  -0.882  -0.851  -0.890  -0.893  -0.813
9     I        -0.064  -0.022  -0.054  -0.360  -0.357  -0.364  -0.324  -0.290  -0.296
10    K        -0.494  -0.501  -0.545  -0.516  -0.552  -0.606  -0.550  -0.577  -0.595
11    S        -0.064  -0.131  -0.050  -0.176  -0.249  -0.128  -0.324  -0.394  -0.290
12    R         1.012   0.894   0.807   1.172   1.009   0.873   1.033   0.840   0.652
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    S        -0.243  -0.380  -0.485  -0.115  -0.300  -0.471  -0.211  -0.386  -0.514
16    K        -0.494  -0.579  -0.552  -0.398  -0.502  -0.459  -0.550  -0.640  -0.600
17    G        -1.118  -1.126  -1.000  -1.128  -1.123  -0.956  -1.003  -0.999  -0.851
18    L        -0.064  -0.082  -0.057  -0.459  -0.471  -0.420  -0.324  -0.348  -0.299
19    R         0.069  -0.018  -0.020   0.099  -0.006  -0.020  -0.098  -0.210  -0.240
20    D        -1.118  -1.090  -1.010  -1.031  -0.989  -0.868  -1.003  -0.969  -0.857
21    -         0.789   0.882   0.731   0.461   0.598   0.351   0.667   0.819   0.510
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    T        -1.118  -1.074  -1.008  -1.102  -1.031  -0.947  -1.003  -0.958  -0.856
24    E        -1.001  -0.925  -0.960  -0.946  -0.835  -0.866  -0.890  -0.812  -0.811
25    I        -0.806  -0.658  -0.860  -0.856  -0.665  -0.915  -0.663  -0.499  -0.707
26    D         0.366   0.425   0.128   0.675   0.747   0.346   0.355   0.436  -0.008
27    L         0.069   0.069  -0.009  -0.273  -0.271  -0.399  -0.098  -0.096  -0.224
28    S        -0.571  -0.474  -0.534  -0.537  -0.418  -0.457  -0.663  -0.569  -0.590
29    K        -1.743  -1.710  -1.607  -1.510  -1.487  -1.357  -1.229  -1.200  -1.070
30    K        -0.494  -0.438  -0.535  -0.279  -0.201  -0.380  -0.550  -0.486  -0.585
31    P        -1.313  -1.348  -1.298  -1.060  -1.113  -1.031  -1.003  -1.034  -0.952
32    T         0.678   0.712   0.672   0.676   0.733   0.618   0.468   0.521   0.397
33    L        -0.064  -0.049  -0.050  -0.392  -0.346  -0.337  -0.324  -0.295  -0.283
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    D        -0.689  -0.662  -0.591  -0.479  -0.446  -0.347  -0.777  -0.739  -0.647
37    D        -1.118  -1.078  -0.993  -0.924  -0.872  -0.755  -1.003  -0.964  -0.845
38    V        -0.064  -0.122  -0.053  -0.386  -0.445  -0.341  -0.324  -0.380  -0.290
39    L        -0.806  -0.877  -0.929  -0.903  -1.018  -1.070  -0.663  -0.744  -0.777
40    K        -1.431  -1.391  -1.310  -1.105  -1.043  -0.948  -1.116  -1.078  -0.965
41    K        -1.001  -0.985  -0.952  -0.862  -0.848  -0.825  -0.890  -0.876  -0.807
42    I        -0.259  -0.226  -0.129  -0.598  -0.548  -0.424  -0.550  -0.507  -0.386
43    S         1.012   0.894   0.807   1.021   0.879   0.746   1.033   0.840   0.652
44    A        -0.806  -0.776  -0.650  -0.925  -0.877  -0.698  -0.890  -0.856  -0.705
45    N        -1.743  -1.716  -1.617  -1.367  -1.327  -1.207  -1.229  -1.205  -1.077
46    N        -0.494  -0.537  -0.546  -0.346  -0.430  -0.427  -0.550  -0.608  -0.595
47    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    N        -0.806  -0.877  -0.929  -0.488  -0.606  -0.684  -0.663  -0.744  -0.777
49    I         0.678   0.660   0.643   0.542   0.495   0.396   0.468   0.427   0.340
50    S         0.366   0.238   0.089   0.459   0.298   0.081   0.355   0.168  -0.065
51    K        -0.494  -0.518  -0.527  -0.436  -0.462  -0.469  -0.550  -0.578  -0.575
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    Y        -1.313  -1.232  -1.276  -0.938  -0.837  -0.900  -1.003  -0.926  -0.934
54    R         1.691   1.705   1.779   1.767   1.778   1.899   1.825   1.847   1.960
55    I         0.442   0.462   0.566  -0.025   0.014   0.180   0.015   0.043   0.187
56    R         1.012   0.894   0.807   1.186   1.027   0.903   1.033   0.840   0.652
57    L         1.012   1.001   0.825   0.762   0.750   0.497   1.033   1.013   0.686
58    T         0.069  -0.012  -0.017   0.093  -0.025  -0.099  -0.098  -0.201  -0.235
59    Y        -1.313  -1.322  -1.315  -0.941  -0.960  -0.961  -1.003  -1.013  -0.966
60    K        -0.689  -0.691  -0.590  -0.877  -0.845  -0.738  -0.777  -0.763  -0.646
61    K        -0.259  -0.254  -0.143  -0.314  -0.303  -0.140  -0.550  -0.545  -0.404
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    E        -0.547  -0.553  -0.592  -0.359  -0.388  -0.483  -0.588  -0.599  -0.640
72    S        -0.966  -1.016  -0.969  -0.788  -0.874  -0.841  -0.834  -0.889  -0.816
73    K         1.691   1.705   1.779   1.641   1.667   1.777   1.825   1.847   1.960
74    Q        -0.243  -0.380  -0.485   0.172  -0.030  -0.208  -0.211  -0.386  -0.514
75    V        -0.494  -0.535  -0.550  -0.517  -0.597  -0.638  -0.550  -0.611  -0.601
76    P        -1.001  -1.059  -0.965  -0.886  -1.016  -0.880  -0.890  -0.934  -0.818
77    V        -0.494  -0.522  -0.551  -0.751  -0.791  -0.816  -0.550  -0.577  -0.598
78    -        -1.537  -1.496  -1.363  -1.484  -1.439  -1.250  -1.191  -1.154  -1.003
79    -         0.128   0.153   0.024   0.291   0.315   0.109   0.015   0.041  -0.162
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    S        -1.313  -1.321  -1.281  -0.941  -0.968  -0.910  -1.003  -1.011  -0.938
84    E        -1.431  -1.453  -1.339  -1.202  -1.266  -1.085  -1.116  -1.125  -0.986
85    S        -0.689  -0.695  -0.611  -0.736  -0.749  -0.638  -0.777  -0.779  -0.667
86    F        -1.313  -1.359  -1.297  -1.290  -1.369  -1.296  -1.003  -1.043  -0.952
87    F        -1.431  -1.418  -1.330  -1.286  -1.258  -1.129  -1.116  -1.101  -0.979
88    Q        -1.001  -0.957  -0.957  -0.779  -0.728  -0.694  -0.890  -0.852  -0.811
89    E        -1.001  -1.031  -0.970  -0.795  -0.852  -0.751  -0.890  -0.919  -0.823
90    E        -0.494  -0.425  -0.535  -0.489  -0.411  -0.584  -0.550  -0.477  -0.585
91    A        -1.118  -1.067  -1.000  -1.137  -1.074  -0.959  -1.003  -0.953  -0.850
92    D        -1.001  -1.014  -0.958  -0.869  -0.895  -0.806  -0.890  -0.896  -0.809
93    D        -1.001  -0.962  -0.963  -0.853  -0.800  -0.796  -0.890  -0.850  -0.817
94    S        -1.001  -1.023  -0.953  -0.927  -0.953  -0.855  -0.890  -0.905  -0.807
95    M        -1.431  -1.430  -1.322  -1.090  -1.107  -0.938  -1.116  -1.109  -0.974
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    E         0.069   0.076  -0.001   0.214   0.227   0.084  -0.098  -0.082  -0.209
100   F        -0.806  -0.773  -0.897  -0.903  -0.863  -1.029  -0.663  -0.627  -0.745
101   F        -0.571  -0.634  -0.546  -0.626  -0.700  -0.567  -0.663  -0.718  -0.601
102   I         0.366   0.478   0.145   0.508   0.648   0.203   0.355   0.509   0.016
103   K         1.691   1.705   1.779   1.645   1.670   1.781   1.825   1.847   1.960
104   D         1.691   1.705   1.779   1.848   1.867   1.977   1.825   1.847   1.960
105   L         1.691   1.705   1.779   1.374   1.395   1.518   1.825   1.847   1.960
106   G         1.691   1.705   1.779   1.745   1.761   1.877   1.825   1.847   1.960
107   P         1.691   1.705   1.779   1.785   1.800   1.916   1.825   1.847   1.960
108   Q         1.691   1.705   1.779   1.878   1.898   2.006   1.825   1.847   1.960
109   I         1.691   1.705   1.779   1.708   1.725   1.841   1.825   1.847   1.960
110   S        -0.494  -0.543  -0.545  -0.471  -0.542  -0.530  -0.550  -0.609  -0.595
111   W         1.691   1.705   1.779   1.864   1.884   1.993   1.825   1.847   1.960
112   R         1.691   1.705   1.779   1.767   1.778   1.899   1.825   1.847   1.960
113   L         0.499   0.543   0.604   0.215   0.306   0.357   0.128   0.203   0.264
114   V         1.691   1.705   1.779   1.660   1.681   1.795   1.825   1.847   1.960
115   F         1.691   1.705   1.779   1.542   1.569   1.680   1.825   1.847   1.960
116   F        -1.118  -1.077  -1.002  -1.227  -1.147  -1.054  -1.003  -0.962  -0.851
117   C        -0.494  -0.440  -0.505  -0.380  -0.317  -0.433  -0.550  -0.485  -0.545
118   E         1.691   1.705   1.779   1.812   1.829   1.942   1.825   1.847   1.960
119   Y         1.691   1.705   1.779   1.743   1.766   1.875   1.825   1.847   1.960
120   L        -0.064  -0.040  -0.043  -0.535  -0.501  -0.468  -0.324  -0.297  -0.279
121   G         1.691   1.705   1.779   1.745   1.761   1.877   1.825   1.847   1.960
122   P         1.691   1.705   1.779   1.785   1.800   1.916   1.825   1.847   1.960
123   V        -0.571  -0.496  -0.548  -0.859  -0.752  -0.812  -0.663  -0.589  -0.603
124   L         0.069   0.099   0.007  -0.228  -0.180  -0.309  -0.098  -0.047  -0.199
125   V        -0.689  -0.681  -0.601  -0.818  -0.815  -0.699  -0.777  -0.763  -0.657
126   H         1.691   1.705   1.779   1.866   1.888   1.994   1.825   1.847   1.960
127   S        -1.001  -1.040  -0.984  -0.957  -1.025  -0.982  -0.890  -0.919  -0.833
128   L         0.366   0.326   0.102   0.180   0.127  -0.203   0.355   0.296  -0.047
129   F        -0.494  -0.522  -0.542  -0.668  -0.714  -0.771  -0.550  -0.590  -0.592
130   Y        -0.243  -0.380  -0.485  -0.001  -0.197  -0.394  -0.211  -0.386  -0.514
131   Y        -0.494  -0.456  -0.510  -0.731  -0.678  -0.737  -0.550  -0.495  -0.554
132   L        -0.806  -0.738  -0.906  -0.930  -0.830  -1.079  -0.663  -0.591  -0.753
133   S        -0.494  -0.576  -0.552  -0.408  -0.506  -0.465  -0.550  -0.637  -0.601
134   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   R        -0.494  -0.495  -0.512  -0.486  -0.463  -0.496  -0.550  -0.541  -0.551
142   W        -0.571  -0.473  -0.531  -0.641  -0.491  -0.587  -0.663  -0.568  -0.586
143   H        -1.001  -1.054  -0.994  -0.770  -0.851  -0.806  -0.890  -0.929  -0.842
144   S        -0.689  -0.605  -0.586  -0.715  -0.569  -0.560  -0.777  -0.675  -0.637
145   A        -1.118  -1.053  -0.997  -1.064  -0.988  -0.882  -1.003  -0.945  -0.848
146   S        -1.118  -1.110  -1.006  -1.050  -1.024  -0.878  -1.003  -0.986  -0.854
147   S        -0.494  -0.563  -0.535  -0.474  -0.544  -0.504  -0.550  -0.620  -0.580
148   D        -1.313  -1.323  -1.305  -1.074  -1.098  -1.030  -1.003  -1.012  -0.958
149   Y        -1.001  -0.927  -0.953  -0.738  -0.634  -0.674  -0.890  -0.811  -0.804
150   N        -1.431  -1.460  -1.341  -1.162  -1.214  -1.069  -1.116  -1.129  -0.987
151   P        -0.571  -0.535  -0.553  -0.369  -0.326  -0.302  -0.663  -0.624  -0.607
152   F        -0.806  -0.806  -0.911  -0.666  -0.671  -0.802  -0.663  -0.670  -0.759
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   L        -1.431  -1.448  -1.339  -1.497  -1.527  -1.368  -1.116  -1.121  -0.986
156   N         0.069   0.137   0.007   0.277   0.384   0.166  -0.098   0.002  -0.193
157   R        -0.806  -0.797  -0.895  -0.631  -0.607  -0.788  -0.663  -0.660  -0.743
158   V        -0.689  -0.630  -0.584  -1.099  -1.006  -0.931  -0.777  -0.700  -0.639
159   A        -0.494  -0.569  -0.542  -0.476  -0.624  -0.604  -0.550  -0.627  -0.588
160   Y         0.442   0.467   0.567   0.124   0.157   0.305   0.015   0.053   0.188
161   F        -1.431  -1.384  -1.316  -1.233  -1.176  -1.074  -1.116  -1.073  -0.970
162   L         1.012   1.087   0.842   0.787   0.879   0.574   1.033   1.146   0.716
163   I        -1.001  -1.044  -0.987  -0.885  -0.953  -0.853  -0.890  -0.923  -0.835
164   L        -0.571  -0.610  -0.548  -0.622  -0.642  -0.541  -0.663  -0.695  -0.602
165   G        -0.243  -0.147  -0.446  -0.355  -0.230  -0.635  -0.211  -0.091  -0.467
166   H         1.691   1.705   1.779   1.866   1.888   1.994   1.825   1.847   1.960
167   Y         0.499   0.543   0.604   0.203   0.279   0.360   0.128   0.203   0.264
168   G        -0.243  -0.208  -0.433  -0.286  -0.241  -0.505  -0.211  -0.169  -0.451
169   K         1.691   1.705   1.779   1.645   1.670   1.781   1.825   1.847   1.960
170   R         1.691   1.705   1.779   1.767   1.778   1.899   1.825   1.847   1.960
171   L         0.366   0.425   0.128   0.588   0.667   0.191   0.355   0.436  -0.008
172   F        -0.689  -0.652  -0.592  -0.946  -0.849  -0.815  -0.777  -0.726  -0.646
173   E         1.691   1.705   1.779   1.812   1.829   1.942   1.825   1.847   1.960
174   T         0.678   0.686   0.637   0.676   0.689   0.547   0.468   0.475   0.329
175   L        -0.064   0.003  -0.049  -0.432  -0.353  -0.377  -0.324  -0.249  -0.287
176   F         1.012   0.992   0.821   0.961   0.946   0.713   1.033   0.999   0.678
177   V         0.069   0.101  -0.003  -0.005   0.040  -0.165  -0.098  -0.055  -0.216
178   H         1.691   1.705   1.779   1.866   1.888   1.994   1.825   1.847   1.960
179   Q        -0.243  -0.180  -0.432  -0.054   0.032  -0.324  -0.211  -0.134  -0.450
180   F         1.691   1.705   1.779   1.542   1.569   1.680   1.825   1.847   1.960
181   S         1.691   1.705   1.779   1.603   1.634   1.740   1.825   1.847   1.960
182   L        -1.001  -1.034  -0.970  -1.117  -1.162  -1.037  -0.890  -0.911  -0.820
183   A         0.366   0.303   0.102   0.591   0.489   0.224   0.355   0.256  -0.047
184   T         1.691   1.705   1.779   1.771   1.793   1.903   1.825   1.847   1.960
185   M         1.691   1.705   1.779   1.910   1.926   2.037   1.825   1.847   1.960
186   P         1.691   1.705   1.779   1.785   1.800   1.916   1.825   1.847   1.960
187   I        -0.494  -0.431  -0.518  -0.722  -0.655  -0.733  -0.550  -0.493  -0.564
188   F         1.012   1.001   0.825   0.965   0.959   0.727   1.033   1.013   0.686
189   N         1.691   1.705   1.779   1.734   1.757   1.867   1.825   1.847   1.960
190   L         0.442   0.461   0.564  -0.025   0.007   0.164   0.015   0.040   0.182
191   F         1.012   1.096   0.841   0.908   1.026   0.638   1.033   1.159   0.713
192   K         1.012   0.894   0.807   1.068   0.923   0.796   1.033   0.840   0.652
193   N         1.691   1.705   1.779   1.734   1.757   1.867   1.825   1.847   1.960
194   C         0.678   0.698   0.641   0.632   0.667   0.584   0.468   0.496   0.338
195   F        -0.806  -0.773  -0.649  -0.995  -0.935  -0.764  -0.890  -0.852  -0.704
196   H         0.366   0.230   0.079   0.681   0.487   0.227   0.355   0.157  -0.081
197   Y         1.691   1.705   1.779   1.743   1.766   1.875   1.825   1.847   1.960
198   W         1.012   1.001   0.825   1.300   1.289   1.057   1.033   1.013   0.686
199   V        -0.494  -0.525  -0.547  -0.615  -0.728  -0.771  -0.550  -0.601  -0.597
200   L         1.012   0.992   0.821   0.787   0.764   0.543   1.033   0.999   0.678
201   S        -0.182  -0.195  -0.114  -0.343  -0.369  -0.253  -0.437  -0.463  -0.364
202   G         1.691   1.705   1.779   1.745   1.761   1.877   1.825   1.847   1.960
203   L        -0.064  -0.021  -0.036  -0.559  -0.488  -0.494  -0.324  -0.264  -0.267
204   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   S        -1.001  -1.040  -0.984  -0.885  -0.914  -0.859  -0.890  -0.919  -0.833
206   F        -0.243  -0.295  -0.459  -0.326  -0.383  -0.603  -0.211  -0.283  -0.482
207   G        -0.259  -0.220  -0.119  -0.451  -0.404  -0.253  -0.550  -0.503  -0.373
208   Y         0.069  -0.007  -0.017   0.011  -0.111  -0.203  -0.098  -0.193  -0.232
209   F         1.012   0.894   0.807   0.977   0.841   0.724   1.033   0.840   0.652
210   G        -0.064  -0.056  -0.052  -0.132  -0.115  -0.103  -0.324  -0.302  -0.286
211   Y         1.691   1.705   1.779   1.743   1.766   1.875   1.825   1.847   1.960
212   G         0.366   0.230   0.079   0.595   0.406   0.185   0.355   0.157  -0.081
213   F         0.499   0.543   0.604   0.313   0.394   0.457   0.128   0.203   0.264
214   P        -0.966  -1.022  -0.968  -0.760  -0.858  -0.819  -0.834  -0.892  -0.815
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   F        -0.704  -0.660  -0.617  -0.895  -0.837  -0.740  -0.789  -0.741  -0.671
219   G        -0.547  -0.567  -0.564  -0.323  -0.360  -0.363  -0.588  -0.615  -0.608
220   N        -0.547  -0.553  -0.592  -0.453  -0.455  -0.566  -0.588  -0.599  -0.640
221   A        -0.704  -0.670  -0.608  -0.752  -0.698  -0.596  -0.789  -0.750  -0.661
222   K        -1.121  -1.102  -1.022  -1.010  -0.978  -0.900  -0.990  -0.971  -0.865
223   L         0.879   0.905   0.748   0.605   0.644   0.409   0.820   0.859   0.543
224   F        -1.121  -1.111  -1.006  -1.092  -1.073  -0.969  -0.990  -0.979  -0.851
225   K         0.128   0.169   0.008   0.193   0.247   0.017   0.015   0.072  -0.185
226   Y        -0.704  -0.702  -0.611  -0.777  -0.767  -0.650  -0.789  -0.784  -0.665
227   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   Y        -1.101  -1.089  -0.997  -1.400  -1.394  -1.227  -0.982  -0.969  -0.846
230   L        -0.118  -0.184  -0.090  -0.583  -0.653  -0.501  -0.391  -0.460  -0.338
231   K        -0.494  -0.562  -0.540  -0.291  -0.368  -0.382  -0.550  -0.617  -0.585
232   L        -1.431  -1.448  -1.339  -1.465  -1.482  -1.297  -1.116  -1.121  -0.986
233   D        -0.806  -0.745  -0.909  -0.492  -0.408  -0.659  -0.663  -0.596  -0.757
234   D        -0.243  -0.195  -0.426   0.095   0.153  -0.214  -0.211  -0.153  -0.442
235   L        -0.571  -0.557  -0.533  -0.939  -0.917  -0.855  -0.663  -0.644  -0.588
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.208  -1.171  -1.044  -1.181  -1.124  -0.956  -1.071  -1.033  -0.884
240   -        -0.709  -0.612  -0.603  -0.939  -0.802  -0.771  -0.781  -0.668  -0.653
241   -        -0.209  -0.188  -0.112  -0.668  -0.655  -0.541  -0.491  -0.460  -0.364
242   -        -0.709  -0.659  -0.612  -0.926  -0.851  -0.765  -0.781  -0.728  -0.663
243   S        -1.001  -0.954  -0.964  -0.893  -0.830  -0.871  -0.890  -0.844  -0.817
244   T        -1.431  -1.382  -1.327  -1.425  -1.413  -1.276  -1.116  -1.075  -0.977
245   L        -0.243  -0.380  -0.485  -0.300  -0.483  -0.592  -0.211  -0.386  -0.514
246   I        -1.118  -1.053  -0.994  -1.103  -1.026  -0.933  -1.003  -0.946  -0.845
247   G        -0.064  -0.051  -0.045  -0.087  -0.092  -0.046  -0.324  -0.316  -0.286
248   L         1.691   1.705   1.779   1.381   1.403   1.525   1.825   1.847   1.960
249   F         0.442   0.461   0.565   0.215   0.238   0.390   0.015   0.041   0.184
250   V        -0.689  -0.648  -0.598  -0.977  -0.925  -0.816  -0.777  -0.738  -0.654
251   L        -1.001  -1.044  -0.987  -1.181  -1.223  -1.127  -0.890  -0.923  -0.835
252   S        -0.571  -0.639  -0.582  -0.545  -0.608  -0.503  -0.663  -0.722  -0.636
253   E         1.012   1.001   0.825   1.219   1.204   0.950   1.033   1.013   0.686
254   L        -0.494  -0.507  -0.541  -0.642  -0.675  -0.643  -0.550  -0.578  -0.592
255   W        -0.494  -0.517  -0.551  -0.413  -0.415  -0.473  -0.550  -0.574  -0.598
256   N         1.691   1.705   1.779   1.734   1.757   1.867   1.825   1.847   1.960
257   F         0.366   0.315   0.106   0.351   0.299  -0.037   0.355   0.271  -0.041
258   Y        -1.313  -1.322  -1.315  -0.940  -0.972  -0.959  -1.003  -1.013  -0.966
259   C        -0.494  -0.522  -0.551  -0.310  -0.356  -0.387  -0.550  -0.577  -0.598
260   H         1.691   1.705   1.779   1.866   1.888   1.994   1.825   1.847   1.960
261   I        -1.001  -1.039  -0.968  -1.175  -1.202  -1.090  -0.890  -0.923  -0.821
262   K        -1.118  -1.119  -1.011  -1.026  -1.012  -0.858  -1.003  -0.996  -0.859
263   L         1.691   1.705   1.779   1.374   1.395   1.518   1.825   1.847   1.960
264   R        -0.064  -0.017  -0.050  -0.102  -0.066  -0.088  -0.324  -0.281  -0.291
265   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   D        -0.064  -0.017  -0.050  -0.087  -0.044  -0.073  -0.324  -0.281  -0.291
269   Y         0.366   0.457   0.131   0.235   0.348  -0.058   0.355   0.481  -0.004
270   Q         0.499   0.543   0.604   0.472   0.531   0.620   0.128   0.203   0.264
271   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   K        -0.806  -0.747  -0.881  -0.605  -0.521  -0.730  -0.663  -0.600  -0.728
273   H        -2.055  -2.011  -1.868  -1.512  -1.455  -1.277  -1.342  -1.307  -1.151
274   G         0.366   0.502   0.144   0.609   0.772   0.309   0.355   0.542   0.015
275   N        -1.001  -0.975  -0.970  -0.936  -0.898  -0.884  -0.890  -0.864  -0.821
276   A        -0.571  -0.490  -0.549  -0.538  -0.441  -0.485  -0.663  -0.585  -0.604
277   K        -1.313  -1.301  -1.289  -1.029  -1.008  -0.997  -1.003  -0.994  -0.945
278   I        -1.101  -1.077  -1.003  -0.933  -0.897  -0.800  -0.982  -0.951  -0.850
279   R        -0.571  -0.639  -0.582  -0.557  -0.648  -0.564  -0.663  -0.722  -0.636
280   V         0.499   0.543   0.604   0.305   0.379   0.454   0.128   0.203   0.264
281   P         1.691   1.705   1.779   1.785   1.800   1.916   1.825   1.847   1.960
282   L        -1.001  -1.021  -0.986  -1.228  -1.242  -1.149  -0.890  -0.906  -0.836
283   N        -0.064  -0.123  -0.063  -0.046  -0.098   0.002  -0.324  -0.381  -0.302
284   Q        -0.806  -0.812  -0.929  -0.486  -0.505  -0.683  -0.663  -0.675  -0.776
285   G         1.691   1.705   1.779   1.745   1.761   1.877   1.825   1.847   1.960
286   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   F         1.012   0.894   0.807   0.940   0.792   0.647   1.033   0.840   0.652
288   N         0.366   0.490   0.150   0.585   0.741   0.284   0.355   0.526   0.023
289   L         0.069   0.162   0.041  -0.162  -0.035  -0.185  -0.098   0.042  -0.143
290   F         0.069   0.144   0.003  -0.102   0.023  -0.257  -0.098   0.007  -0.200
291   V        -0.064  -0.123  -0.063  -0.247  -0.300  -0.214  -0.324  -0.381  -0.302
292   A        -0.571  -0.634  -0.579  -0.422  -0.527  -0.466  -0.663  -0.718  -0.634
293   P         1.691   1.705   1.779   1.785   1.800   1.916   1.825   1.847   1.960
294   N         1.691   1.705   1.779   1.734   1.757   1.867   1.825   1.847   1.960
295   Y         1.691   1.705   1.779   1.743   1.766   1.875   1.825   1.847   1.960
296   T        -0.494  -0.529  -0.550  -0.511  -0.530  -0.566  -0.550  -0.582  -0.597
297   F         1.691   1.705   1.779   1.542   1.569   1.680   1.825   1.847   1.960
298   E         1.691   1.705   1.779   1.812   1.829   1.942   1.825   1.847   1.960
299   V         0.442   0.465   0.568   0.107   0.154   0.303   0.015   0.050   0.192
300   W        -0.064  -0.056  -0.052  -0.326  -0.319  -0.287  -0.324  -0.302  -0.286
301   S         0.069   0.022  -0.020   0.020  -0.053  -0.115  -0.098  -0.173  -0.241
302   W         1.691   1.705   1.779   1.864   1.884   1.993   1.825   1.847   1.960
303   I        -0.571  -0.593  -0.558  -0.761  -0.791  -0.678  -0.663  -0.682  -0.613
304   W        -0.689  -0.724  -0.598  -0.736  -0.779  -0.596  -0.777  -0.802  -0.653
305   F        -0.494  -0.544  -0.540  -0.560  -0.618  -0.621  -0.550  -0.593  -0.583
306   T         0.069   0.017  -0.001   0.149   0.073   0.036  -0.098  -0.156  -0.204
307   F         0.678   0.721   0.685   0.264   0.334   0.251   0.468   0.538   0.422
308   V        -0.494  -0.516  -0.542  -0.683  -0.714  -0.699  -0.550  -0.587  -0.593
309   F        -1.431  -1.460  -1.341  -1.316  -1.346  -1.159  -1.116  -1.129  -0.987
310   K        -0.259  -0.260  -0.145  -0.404  -0.412  -0.239  -0.550  -0.553  -0.406
311   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   N         0.678   0.608   0.627   0.640   0.512   0.494   0.468   0.328   0.309
313   L        -0.494  -0.529  -0.550  -0.398  -0.431  -0.514  -0.550  -0.582  -0.597
314   F        -0.259  -0.264  -0.146  -0.589  -0.586  -0.409  -0.550  -0.558  -0.408
315   A        -0.064  -0.124  -0.041  -0.198  -0.275  -0.160  -0.324  -0.383  -0.278
316   V        -0.571  -0.561  -0.559  -0.549  -0.539  -0.562  -0.663  -0.648  -0.613
317   L        -0.182  -0.121  -0.081  -0.439  -0.328  -0.311  -0.437  -0.353  -0.316
318   F         1.691   1.705   1.779   1.542   1.569   1.680   1.825   1.847   1.960
319   L         0.366   0.230   0.079   0.221   0.041  -0.157   0.355   0.157  -0.081
320   T        -0.494  -0.405  -0.502  -0.462  -0.341  -0.485  -0.550  -0.446  -0.543
321   V         0.366   0.230   0.079   0.508   0.328   0.103   0.355   0.157  -0.081
322   S        -0.064  -0.016  -0.051  -0.202  -0.145  -0.156  -0.324  -0.283  -0.292
323   T        -1.001  -0.959  -0.944  -0.936  -0.871  -0.874  -0.890  -0.845  -0.797
324   A        -1.001  -1.015  -0.973  -0.832  -0.871  -0.807  -0.890  -0.901  -0.825
325   Q         1.012   0.894   0.807   1.296   1.146   1.005   1.033   0.840   0.652
326   M         1.691   1.705   1.779   1.910   1.926   2.037   1.825   1.847   1.960
327   Y        -0.494  -0.538  -0.534  -0.335  -0.391  -0.413  -0.550  -0.587  -0.577
328   A        -0.494  -0.560  -0.548  -0.767  -0.872  -0.826  -0.550  -0.631  -0.597
329   W         1.691   1.705   1.779   1.864   1.884   1.993   1.825   1.847   1.960
330   A         1.012   0.894   0.807   1.132   0.963   0.828   1.033   0.840   0.652
331   Q        -0.571  -0.634  -0.579  -0.472  -0.552  -0.483  -0.663  -0.718  -0.634
332   K         0.366   0.230   0.079   0.518   0.344   0.137   0.355   0.157  -0.081
333   K         1.691   1.705   1.779   1.645   1.670   1.781   1.825   1.847   1.960
334   N        -0.064  -0.123  -0.063   0.020  -0.039   0.040  -0.324  -0.381  -0.302
335   K        -0.494  -0.504  -0.550  -0.398  -0.439  -0.459  -0.550  -0.580  -0.601
336   K        -0.064  -0.123  -0.063  -0.129  -0.202  -0.111  -0.324  -0.381  -0.302
337   Y         1.012   0.894   0.807   1.111   0.944   0.771   1.033   0.840   0.652
338   H        -1.313  -1.328  -1.308  -1.296  -1.320  -1.236  -1.003  -1.016  -0.960
339   T        -0.571  -0.639  -0.582  -0.538  -0.617  -0.531  -0.663  -0.722  -0.636
340   -        -0.021   0.117  -0.022   0.079   0.292   0.035  -0.202  -0.004  -0.229
341   -         1.691   1.705   1.779   1.556   1.583   1.694   1.825   1.847   1.960
342   -         0.789   0.797   0.712   0.832   0.840   0.695   0.667   0.675   0.475
343   -         0.789   0.797   0.712   0.968   0.976   0.822   0.667   0.675   0.475
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -         1.691   1.705   1.779   1.760   1.785   1.891   1.825   1.847   1.960
346   -         0.479   0.488   0.573   0.285   0.295   0.418   0.088   0.096   0.201
347   -        -0.209  -0.229  -0.117  -0.343  -0.379  -0.210  -0.491  -0.512  -0.370
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   R        -0.494  -0.502  -0.523  -0.461  -0.466  -0.511  -0.550  -0.552  -0.566
350   R         1.691   1.705   1.779   1.767   1.778   1.899   1.825   1.847   1.960
351   A        -0.571  -0.581  -0.569  -0.572  -0.592  -0.550  -0.663  -0.671  -0.623
352   F        -0.689  -0.725  -0.618  -0.851  -0.883  -0.726  -0.777  -0.804  -0.674
353   L        -0.259  -0.199  -0.119  -0.477  -0.353  -0.237  -0.550  -0.475  -0.372
354   I         0.069  -0.007  -0.017   0.022  -0.108  -0.174  -0.098  -0.193  -0.232
355   P         1.691   1.705   1.779   1.785   1.800   1.916   1.825   1.847   1.960
356   F         1.012   0.894   0.807   0.961   0.819   0.691   1.033   0.840   0.652
357   V        -0.494  -0.450  -0.507  -0.790  -0.721  -0.803  -0.550  -0.488  -0.551
358   F        -0.689  -0.656  -0.616  -1.016  -0.992  -0.901  -0.777  -0.751  -0.673
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q99190
Output conservation file - output/Q99190
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
