1     M         1.647   1.652   1.703   1.887   1.900   1.978   1.829   1.836   1.912
2     T        -0.402  -0.409  -0.419  -0.448  -0.460  -0.484  -0.533  -0.541  -0.550
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    I         0.539   0.546   0.476   0.499   0.511   0.399   0.412   0.424   0.282
16    D        -0.978  -0.951  -0.957  -0.964  -0.920  -0.933  -0.892  -0.858  -0.844
17    G        -1.525  -1.520  -1.458  -1.406  -1.397  -1.300  -1.194  -1.187  -1.098
18    D        -0.978  -0.973  -0.959  -1.004  -0.998  -0.988  -0.892  -0.883  -0.847
19    V        -0.978  -0.987  -0.978  -0.971  -0.990  -0.989  -0.892  -0.899  -0.867
20    H        -0.978  -0.945  -0.983  -0.915  -0.860  -0.921  -0.892  -0.852  -0.873
21    E         0.392   0.435   0.409   0.359   0.441   0.366   0.149   0.226   0.158
22    I         1.647   1.652   1.703   1.643   1.647   1.735   1.829   1.836   1.912
23    S         0.661   0.657   0.534   0.654   0.650   0.458   0.620   0.614   0.386
24    P        -0.226  -0.204  -0.313  -0.054  -0.018  -0.213  -0.287  -0.255  -0.404
25    F        -0.978  -0.945  -0.983  -0.805  -0.744  -0.843  -0.892  -0.852  -0.873
26    F         0.661   0.657   0.534   0.703   0.696   0.497   0.620   0.614   0.386
27    Q        -0.978  -0.951  -0.957  -0.990  -0.958  -0.946  -0.892  -0.858  -0.844
28    V         0.661   0.696   0.540   0.774   0.832   0.578   0.620   0.678   0.398
29    R        -0.978  -0.973  -0.959  -0.889  -0.876  -0.869  -0.892  -0.883  -0.847
30    Q        -0.978  -0.980  -0.959  -0.943  -0.952  -0.899  -0.892  -0.892  -0.847
31    T         1.647   1.652   1.703   1.713   1.726   1.805   1.829   1.836   1.912
32    K        -0.978  -0.982  -0.959  -1.010  -1.005  -0.969  -0.892  -0.893  -0.847
33    W         0.281   0.294   0.346   0.256   0.269   0.355  -0.061  -0.036   0.039
34    G         0.661   0.627   0.530   0.820   0.775   0.616   0.620   0.563   0.380
35    G         1.647   1.652   1.703   1.773   1.784   1.864   1.829   1.836   1.912
36    R         1.647   1.652   1.703   1.791   1.801   1.882   1.829   1.836   1.912
37    A         0.321   0.310   0.357   0.325   0.303   0.374   0.015  -0.007   0.059
38    C         1.647   1.652   1.703   1.802   1.812   1.894   1.829   1.836   1.912
39    F         0.661   0.627   0.530   0.703   0.651   0.491   0.620   0.563   0.380
40    S         0.321   0.317   0.354   0.173   0.169   0.232   0.015   0.008   0.054
41    N        -0.978  -0.971  -0.956  -1.022  -1.004  -0.978  -0.892  -0.881  -0.843
42    G        -1.525  -1.520  -1.458  -1.350  -1.342  -1.244  -1.194  -1.187  -1.098
43    N        -1.525  -1.520  -1.458  -1.482  -1.481  -1.376  -1.194  -1.187  -1.098
44    I        -0.226  -0.204  -0.313  -0.216  -0.179  -0.354  -0.287  -0.255  -0.404
45    P        -0.226  -0.204  -0.313  -0.090  -0.055  -0.260  -0.287  -0.255  -0.404
46    K        -0.226  -0.212  -0.305  -0.253  -0.224  -0.365  -0.287  -0.267  -0.393
47    G        -0.226  -0.266  -0.348  -0.013  -0.068  -0.195  -0.287  -0.341  -0.452
48    T         0.661   0.696   0.540   0.785   0.839   0.611   0.620   0.678   0.398
49    T        -0.978  -0.980  -0.959  -0.828  -0.826  -0.796  -0.892  -0.892  -0.847
50    V        -0.432  -0.430  -0.423  -0.593  -0.593  -0.589  -0.590  -0.584  -0.558
51    L         0.321   0.310   0.357   0.116   0.109   0.187   0.015  -0.007   0.059
52    Q        -1.085  -1.066  -1.020  -1.121  -1.104  -1.017  -1.005  -0.983  -0.910
53    V        -0.978  -1.005  -0.988  -0.943  -0.989  -0.977  -0.892  -0.919  -0.878
54    S        -0.226  -0.212  -0.305  -0.239  -0.215  -0.365  -0.287  -0.267  -0.393
55    N        -1.525  -1.520  -1.458  -1.406  -1.398  -1.300  -1.194  -1.187  -1.098
56    F        -1.525  -1.520  -1.458  -1.148  -1.136  -1.043  -1.194  -1.187  -1.098
57    T        -0.978  -0.961  -0.960  -0.970  -0.953  -0.937  -0.892  -0.870  -0.848
58    G         0.661   0.627   0.530   0.796   0.747   0.578   0.620   0.563   0.380
59    T         0.321   0.345   0.375   0.105   0.151   0.194   0.015   0.061   0.095
60    S        -0.226  -0.266  -0.348  -0.187  -0.243  -0.363  -0.287  -0.341  -0.452
61    I         0.661   0.647   0.536   0.627   0.603   0.411   0.620   0.597   0.390
62    S         0.661   0.696   0.540   0.666   0.718   0.488   0.620   0.678   0.398
63    Y        -0.978  -1.005  -0.988  -0.831  -0.868  -0.844  -0.892  -0.919  -0.878
64    E        -0.432  -0.412  -0.418  -0.490  -0.459  -0.459  -0.590  -0.564  -0.552
65    F         1.647   1.652   1.703   1.674   1.682   1.766   1.829   1.836   1.912
66    R         0.321   0.310   0.357   0.173   0.148   0.211   0.015  -0.007   0.059
67    K         1.647   1.652   1.703   1.558   1.573   1.650   1.829   1.836   1.912
68    E         1.647   1.652   1.703   1.573   1.577   1.665   1.829   1.836   1.912
69    V         1.647   1.652   1.703   1.746   1.760   1.838   1.829   1.836   1.912
70    C         1.647   1.652   1.703   1.802   1.812   1.894   1.829   1.836   1.912
71    H         0.321   0.310   0.357   0.280   0.257   0.317   0.015  -0.007   0.059
72    N        -1.525  -1.520  -1.458  -1.399  -1.395  -1.293  -1.194  -1.187  -1.098
73    C         1.647   1.652   1.703   1.802   1.812   1.894   1.829   1.836   1.912
74    F        -0.432  -0.433  -0.401  -0.567  -0.569  -0.521  -0.590  -0.588  -0.533
75    A        -0.226  -0.209  -0.302  -0.236  -0.206  -0.339  -0.287  -0.263  -0.388
76    Y         0.661   0.627   0.530   0.776   0.726   0.568   0.620   0.563   0.380
77    A        -1.525  -1.520  -1.458  -1.368  -1.366  -1.262  -1.194  -1.187  -1.098
78    N        -0.432  -0.436  -0.408  -0.452  -0.452  -0.399  -0.590  -0.590  -0.539
79    A         0.661   0.700   0.543   0.849   0.906   0.680   0.620   0.683   0.403
80    K        -0.226  -0.266  -0.348  -0.289  -0.344  -0.480  -0.287  -0.341  -0.452
81    T        -0.226  -0.204  -0.313  -0.123  -0.083  -0.263  -0.287  -0.255  -0.404
82    M         0.661   0.627   0.530   0.884   0.835   0.649   0.620   0.563   0.380
83    K         1.647   1.652   1.703   1.558   1.573   1.650   1.829   1.836   1.912
84    Y        -0.432  -0.410  -0.419  -0.479  -0.448  -0.447  -0.590  -0.563  -0.553
85    K         0.321   0.312   0.351   0.106   0.100   0.163   0.015  -0.002   0.049
86    L        -0.226  -0.225  -0.310  -0.216  -0.209  -0.348  -0.287  -0.285  -0.399
87    N        -0.226  -0.225  -0.310  -0.214  -0.210  -0.340  -0.287  -0.285  -0.399
88    Y        -1.525  -1.520  -1.458  -1.347  -1.334  -1.241  -1.194  -1.187  -1.098
89    D        -1.525  -1.520  -1.458  -1.272  -1.259  -1.167  -1.194  -1.187  -1.098
90    Y        -0.978  -0.985  -0.979  -1.001  -1.026  -1.025  -0.892  -0.897  -0.869
91    L         0.661   0.647   0.536   0.572   0.555   0.395   0.620   0.597   0.390
92    R        -1.085  -1.066  -1.020  -1.155  -1.139  -1.050  -1.005  -0.983  -0.910
93    D        -0.402  -0.449  -0.419  -0.388  -0.448  -0.423  -0.533  -0.598  -0.550
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    L         0.539   0.437   0.445   0.376   0.221   0.224   0.412   0.231   0.225
96    V        -0.402  -0.353  -0.387  -0.391  -0.309  -0.371  -0.533  -0.464  -0.506
97    C        -0.518  -0.513  -0.455  -0.780  -0.781  -0.677  -0.690  -0.682  -0.597
98    N         0.392   0.416   0.390   0.273   0.316   0.253   0.149   0.192   0.122
99    A        -0.518  -0.513  -0.455  -0.603  -0.608  -0.501  -0.690  -0.682  -0.597
100   H        -0.518  -0.513  -0.455  -0.609  -0.606  -0.507  -0.690  -0.682  -0.597
101   Y        -0.518  -0.513  -0.455  -0.765  -0.751  -0.662  -0.690  -0.682  -0.597
102   Q        -0.518  -0.513  -0.455  -0.409  -0.391  -0.307  -0.690  -0.682  -0.597
103   I        -0.518  -0.513  -0.455  -0.690  -0.686  -0.588  -0.690  -0.682  -0.597
104   N        -0.518  -0.513  -0.455  -0.765  -0.765  -0.662  -0.690  -0.682  -0.597
105   P        -0.518  -0.513  -0.455  -0.660  -0.656  -0.557  -0.690  -0.682  -0.597
106   K         0.392   0.416   0.390   0.285   0.324   0.282   0.149   0.192   0.122
107   K         1.647   1.652   1.703   1.610   1.620   1.702   1.829   1.836   1.912
108   F         0.392   0.368   0.378   0.303   0.259   0.267   0.149   0.103   0.100
109   L         0.392   0.408   0.388   0.124   0.156   0.084   0.149   0.178   0.118
110   G         1.647   1.652   1.703   1.771   1.779   1.863   1.829   1.836   1.912
111   A         0.392   0.368   0.378   0.385   0.335   0.325   0.149   0.103   0.100
112   G         0.539   0.437   0.445   0.602   0.421   0.418   0.412   0.231   0.225
113   L         1.647   1.652   1.703   1.505   1.514   1.597   1.829   1.836   1.912
114   W        -0.226  -0.266  -0.348   0.040  -0.024  -0.178  -0.287  -0.341  -0.452
115   F         1.647   1.652   1.703   1.674   1.682   1.766   1.829   1.836   1.912
116   C         1.647   1.652   1.703   1.802   1.812   1.894   1.829   1.836   1.912
117   S        -0.226  -0.204  -0.313  -0.196  -0.162  -0.321  -0.287  -0.255  -0.404
118   E         0.661   0.696   0.540   0.630   0.676   0.454   0.620   0.678   0.398
119   H        -0.978  -0.961  -0.960  -0.894  -0.870  -0.847  -0.892  -0.870  -0.848
120   C         1.647   1.652   1.703   1.802   1.812   1.894   1.829   1.836   1.912
121   R        -0.432  -0.446  -0.410  -0.610  -0.635  -0.592  -0.590  -0.602  -0.542
122   T        -0.978  -0.945  -0.983  -0.975  -0.924  -0.973  -0.892  -0.852  -0.873
123   S        -1.525  -1.520  -1.458  -1.465  -1.441  -1.358  -1.194  -1.187  -1.098
124   Y         0.321   0.345   0.375   0.174   0.217   0.262   0.015   0.061   0.095
125   L         0.321   0.310   0.357   0.015  -0.000   0.076   0.015  -0.007   0.059
126   Q        -0.978  -0.985  -0.979  -0.921  -0.933  -0.906  -0.892  -0.897  -0.869
127   I        -0.978  -1.005  -0.988  -0.952  -0.998  -0.958  -0.892  -0.919  -0.878
128   P        -0.432  -0.412  -0.418  -0.329  -0.304  -0.287  -0.590  -0.564  -0.552
129   N         0.321   0.310   0.357   0.122   0.094   0.169   0.015  -0.007   0.059
130   I        -0.226  -0.266  -0.348  -0.208  -0.273  -0.400  -0.287  -0.341  -0.452
131   I        -1.525  -1.520  -1.458  -1.314  -1.296  -1.209  -1.194  -1.187  -1.098
132   E        -0.978  -1.005  -0.988  -1.015  -1.060  -1.018  -0.892  -0.919  -0.878
133   L         0.661   0.627   0.530   0.563   0.516   0.372   0.620   0.563   0.380
134   I        -0.226  -0.266  -0.348  -0.262  -0.331  -0.476  -0.287  -0.341  -0.452
135   E        -0.226  -0.258  -0.322  -0.319  -0.373  -0.483  -0.287  -0.330  -0.416
136   C        -0.978  -0.961  -0.960  -0.916  -0.887  -0.886  -0.892  -0.870  -0.848
137   Y         0.321   0.310   0.357   0.097   0.066   0.134   0.015  -0.007   0.059
138   E         0.321   0.310   0.357  -0.048  -0.080  -0.004   0.015  -0.007   0.059
139   I        -0.978  -1.005  -0.988  -0.849  -0.887  -0.839  -0.892  -0.919  -0.878
140   L        -0.432  -0.436  -0.408  -0.680  -0.678  -0.616  -0.590  -0.590  -0.539
141   L         0.321   0.310   0.357  -0.069  -0.095  -0.016   0.015  -0.007   0.059
142   H        -1.525  -1.520  -1.458  -1.449  -1.441  -1.343  -1.194  -1.187  -1.098
143   H        -0.978  -0.987  -0.978  -0.795  -0.804  -0.815  -0.892  -0.899  -0.867
144   F         0.321   0.310   0.357   0.174   0.152   0.228   0.015  -0.007   0.059
145   P        -1.525  -1.520  -1.458  -1.297  -1.299  -1.191  -1.194  -1.187  -1.098
146   S        -0.978  -0.987  -0.978  -0.904  -0.916  -0.885  -0.892  -0.899  -0.867
147   M         0.281   0.285   0.342   0.300   0.307   0.397  -0.061  -0.054   0.031
148   L         0.321   0.331   0.367  -0.036  -0.019   0.039   0.015   0.034   0.080
149   K        -0.226  -0.242  -0.319  -0.277  -0.296  -0.417  -0.287  -0.309  -0.412
150   R        -0.978  -0.945  -0.983  -0.970  -0.916  -0.955  -0.892  -0.852  -0.873
151   Y         0.392   0.408   0.388   0.244   0.272   0.230   0.149   0.178   0.118
152   N         0.392   0.408   0.388   0.219   0.249   0.198   0.149   0.178   0.118
153   Y         0.392   0.408   0.388   0.124   0.151   0.117   0.149   0.178   0.118
154   T        -1.085  -1.063  -1.020  -1.178  -1.143  -1.073  -1.005  -0.980  -0.910
155   S        -1.085  -1.063  -1.020  -1.149  -1.094  -1.044  -1.005  -0.980  -0.910
156   E         1.647   1.652   1.703   1.589   1.590   1.681   1.829   1.836   1.912
157   Q        -0.432  -0.430  -0.423  -0.340  -0.333  -0.322  -0.590  -0.584  -0.558
158   E         0.661   0.657   0.534   0.630   0.621   0.443   0.620   0.614   0.386
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   E        -0.978  -0.982  -0.959  -1.119  -1.135  -1.090  -0.892  -0.893  -0.847
164   K        -0.978  -0.985  -0.979  -0.837  -0.839  -0.837  -0.892  -0.897  -0.869
165   L        -0.432  -0.438  -0.408  -0.548  -0.553  -0.493  -0.590  -0.593  -0.540
166   N        -0.226  -0.242  -0.319  -0.189  -0.219  -0.349  -0.287  -0.309  -0.412
167   S        -1.525  -1.520  -1.458  -1.419  -1.417  -1.313  -1.194  -1.187  -1.098
168   I        -0.432  -0.446  -0.410  -0.706  -0.729  -0.671  -0.590  -0.602  -0.542
169   L        -1.525  -1.520  -1.458  -1.526  -1.517  -1.419  -1.194  -1.187  -1.098
170   I        -0.432  -0.430  -0.423  -0.508  -0.502  -0.462  -0.590  -0.584  -0.558
171   S        -1.525  -1.520  -1.458  -1.271  -1.252  -1.165  -1.194  -1.187  -1.098
172   E        -0.978  -0.951  -0.957  -0.922  -0.865  -0.902  -0.892  -0.858  -0.844
173   N        -0.978  -0.985  -0.979  -0.966  -0.976  -0.950  -0.892  -0.897  -0.869
174   V        -0.402  -0.399  -0.387  -0.415  -0.412  -0.398  -0.533  -0.528  -0.506
175   I         0.661   0.647   0.536   0.687   0.666   0.502   0.620   0.597   0.390
176   Q        -0.518  -0.513  -0.455  -0.618  -0.615  -0.516  -0.690  -0.682  -0.597
177   S        -0.978  -0.987  -0.978  -1.040  -1.052  -1.039  -0.892  -0.899  -0.867
178   S        -0.978  -0.945  -0.983  -1.009  -0.959  -1.004  -0.892  -0.852  -0.873
179   W         1.647   1.652   1.703   1.899   1.908   1.990   1.829   1.836   1.912
180   D        -0.978  -0.982  -0.959  -0.916  -0.921  -0.891  -0.892  -0.893  -0.847
181   E        -0.432  -0.410  -0.419  -0.626  -0.594  -0.604  -0.590  -0.563  -0.553
182   I        -0.432  -0.430  -0.423  -0.593  -0.583  -0.587  -0.590  -0.584  -0.558
183   E         0.392   0.416   0.390   0.244   0.281   0.234   0.149   0.192   0.122
184   S        -0.978  -0.987  -0.978  -0.936  -0.946  -0.921  -0.892  -0.899  -0.867
185   K        -1.525  -1.520  -1.458  -1.539  -1.533  -1.432  -1.194  -1.187  -1.098
186   W         1.647   1.652   1.703   1.899   1.908   1.990   1.829   1.836   1.912
187   I        -0.432  -0.430  -0.423  -0.578  -0.580  -0.530  -0.590  -0.584  -0.558
188   P        -0.226  -0.266  -0.348  -0.062  -0.130  -0.289  -0.287  -0.341  -0.452
189   R        -0.432  -0.412  -0.418  -0.474  -0.448  -0.423  -0.590  -0.564  -0.552
190   I        -0.432  -0.438  -0.408  -0.593  -0.602  -0.563  -0.590  -0.593  -0.540
191   N        -1.525  -1.520  -1.458  -1.458  -1.457  -1.352  -1.194  -1.187  -1.098
192   N        -0.226  -0.209  -0.302  -0.317  -0.286  -0.441  -0.287  -0.263  -0.388
193   M        -0.226  -0.212  -0.305  -0.027  -0.002  -0.183  -0.287  -0.267  -0.393
194   K         1.647   1.652   1.703   1.558   1.573   1.650   1.829   1.836   1.912
195   S        -0.978  -0.971  -0.956  -0.871  -0.855  -0.848  -0.892  -0.881  -0.843
196   A        -0.432  -0.412  -0.418  -0.473  -0.448  -0.440  -0.590  -0.564  -0.552
197   K         1.647   1.652   1.703   1.558   1.573   1.650   1.829   1.836   1.912
198   R         0.661   0.657   0.534   0.866   0.865   0.681   0.620   0.614   0.386
199   I        -1.525  -1.520  -1.458  -1.413  -1.412  -1.307  -1.194  -1.187  -1.098
200   N         0.661   0.696   0.540   0.697   0.752   0.495   0.620   0.678   0.398
201   Q        -0.226  -0.227  -0.309  -0.085  -0.088  -0.238  -0.287  -0.289  -0.398
202   L         0.321   0.310   0.357  -0.036  -0.059   0.020   0.015  -0.007   0.059
203   P         0.661   0.647   0.536   0.866   0.846   0.664   0.620   0.597   0.390
204   P        -1.525  -1.520  -1.458  -1.291  -1.286  -1.185  -1.194  -1.187  -1.098
205   T         0.661   0.700   0.543   0.679   0.732   0.502   0.620   0.683   0.403
206   C        -0.978  -0.961  -0.960  -0.850  -0.820  -0.822  -0.892  -0.870  -0.848
207   E         0.661   0.647   0.536   0.630   0.607   0.446   0.620   0.597   0.390
208   D        -0.226  -0.266  -0.348  -0.145  -0.212  -0.363  -0.287  -0.341  -0.452
209   E         0.661   0.657   0.534   0.667   0.661   0.499   0.620   0.614   0.386
210   Y         1.647   1.652   1.703   1.737   1.745   1.829   1.829   1.836   1.912
211   C        -1.525  -1.520  -1.458  -1.545  -1.550  -1.439  -1.194  -1.187  -1.098
212   C         0.321   0.310   0.357   0.192   0.160   0.230   0.015  -0.007   0.059
213   I        -0.226  -0.227  -0.309  -0.179  -0.185  -0.299  -0.287  -0.289  -0.398
214   R         0.321   0.310   0.357   0.173   0.148   0.211   0.015  -0.007   0.059
215   F         0.321   0.310   0.357   0.174   0.152   0.228   0.015  -0.007   0.059
216   V         0.661   0.627   0.530   0.774   0.728   0.559   0.620   0.563   0.380
217   C        -0.978  -0.961  -0.960  -0.949  -0.922  -0.915  -0.892  -0.870  -0.848
218   E         0.321   0.310   0.357   0.109   0.089   0.170   0.015  -0.007   0.059
219   S        -1.525  -1.520  -1.458  -1.406  -1.394  -1.300  -1.194  -1.187  -1.098
220   L         1.647   1.652   1.703   1.505   1.514   1.597   1.829   1.836   1.912
221   F         1.647   1.652   1.703   1.674   1.682   1.766   1.829   1.836   1.912
222   N        -0.226  -0.227  -0.309  -0.100  -0.101  -0.217  -0.287  -0.289  -0.398
223   L        -0.226  -0.169  -0.314  -0.053   0.047  -0.233  -0.287  -0.207  -0.405
224   K        -0.432  -0.430  -0.423  -0.575  -0.559  -0.545  -0.590  -0.584  -0.558
225   Y        -0.432  -0.410  -0.419  -0.463  -0.431  -0.429  -0.590  -0.563  -0.553
226   M        -0.402  -0.428  -0.410  -0.516  -0.553  -0.505  -0.533  -0.571  -0.536
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   D         0.539   0.437   0.445   0.552   0.370   0.368   0.412   0.231   0.225
245   P        -0.978  -1.005  -0.988  -0.698  -0.738  -0.711  -0.892  -0.919  -0.878
246   Q        -0.978  -0.961  -0.960  -0.911  -0.888  -0.881  -0.892  -0.870  -0.848
247   C        -0.978  -0.985  -0.979  -0.928  -0.932  -0.915  -0.892  -0.897  -0.869
248   I        -0.978  -0.961  -0.960  -0.949  -0.918  -0.931  -0.892  -0.870  -0.848
249   T        -0.432  -0.430  -0.423  -0.638  -0.639  -0.627  -0.590  -0.584  -0.558
250   Y        -0.226  -0.201  -0.309  -0.255  -0.217  -0.356  -0.287  -0.251  -0.398
251   R        -1.525  -1.520  -1.458  -1.610  -1.611  -1.504  -1.194  -1.187  -1.098
252   A        -0.978  -1.005  -0.988  -0.867  -0.916  -0.909  -0.892  -0.919  -0.878
253   F         0.661   0.657   0.534   0.770   0.766   0.599   0.620   0.614   0.386
254   N        -1.525  -1.520  -1.458  -1.329  -1.323  -1.223  -1.194  -1.187  -1.098
255   M        -1.525  -1.520  -1.458  -1.535  -1.537  -1.429  -1.194  -1.187  -1.098
256   L         1.647   1.652   1.703   1.505   1.514   1.597   1.829   1.836   1.912
257   Q         0.661   0.647   0.536   0.858   0.841   0.665   0.620   0.597   0.390
258   S         1.647   1.652   1.703   1.610   1.619   1.702   1.829   1.836   1.912
259   N         0.661   0.647   0.536   0.710   0.689   0.506   0.620   0.597   0.390
260   E         1.647   1.652   1.703   1.573   1.577   1.665   1.829   1.836   1.912
261   L        -0.432  -0.430  -0.423  -0.647  -0.633  -0.610  -0.590  -0.584  -0.558
262   S        -0.432  -0.446  -0.410  -0.648  -0.668  -0.597  -0.590  -0.602  -0.542
263   K         1.647   1.652   1.703   1.558   1.573   1.650   1.829   1.836   1.912
264   I        -0.226  -0.266  -0.348  -0.262  -0.331  -0.476  -0.287  -0.341  -0.452
265   S        -0.978  -0.945  -0.983  -0.946  -0.889  -0.928  -0.892  -0.852  -0.873
266   K         0.321   0.317   0.354   0.106   0.108   0.166   0.015   0.008   0.054
267   F         0.321   0.310   0.357   0.174   0.152   0.228   0.015  -0.007   0.059
268   P         1.647   1.652   1.703   1.829   1.837   1.920   1.829   1.836   1.912
269   V        -0.226  -0.266  -0.348  -0.061  -0.115  -0.250  -0.287  -0.341  -0.452
270   L         1.647   1.652   1.703   1.505   1.514   1.597   1.829   1.836   1.912
271   L         1.647   1.652   1.703   1.505   1.514   1.597   1.829   1.836   1.912
272   H        -1.525  -1.520  -1.458  -1.313  -1.307  -1.207  -1.194  -1.187  -1.098
273   F         0.321   0.310   0.357   0.101   0.075   0.148   0.015  -0.007   0.059
274   Q         0.321   0.310   0.357   0.285   0.263   0.333   0.015  -0.007   0.059
275   K        -0.978  -0.961  -0.960  -1.009  -0.976  -0.980  -0.892  -0.870  -0.848
276   L        -0.432  -0.430  -0.423  -0.707  -0.694  -0.690  -0.590  -0.584  -0.558
277   V         0.321   0.310   0.357   0.174   0.150   0.218   0.015  -0.007   0.059
278   F         0.321   0.310   0.357   0.174   0.152   0.228   0.015  -0.007   0.059
279   Q         0.661   0.700   0.543   0.632   0.693   0.469   0.620   0.683   0.403
280   T        -0.432  -0.430  -0.423  -0.445  -0.439  -0.402  -0.590  -0.584  -0.558
281   L        -0.432  -0.436  -0.408  -0.637  -0.629  -0.578  -0.590  -0.590  -0.539
282   Y        -0.432  -0.412  -0.418  -0.589  -0.561  -0.557  -0.590  -0.564  -0.552
283   I        -0.978  -0.945  -0.983  -1.083  -1.031  -1.073  -0.892  -0.852  -0.873
284   L         0.321   0.310   0.357   0.015  -0.000   0.076   0.015  -0.007   0.059
285   L        -0.432  -0.436  -0.408  -0.513  -0.503  -0.440  -0.590  -0.590  -0.539
286   P        -0.226  -0.266  -0.348   0.031  -0.024  -0.159  -0.287  -0.341  -0.452
287   S        -1.525  -1.520  -1.458  -1.308  -1.294  -1.203  -1.194  -1.187  -1.098
288   H        -1.525  -1.520  -1.458  -1.313  -1.308  -1.207  -1.194  -1.187  -1.098
289   L         1.647   1.652   1.703   1.521   1.530   1.614   1.829   1.836   1.912
290   H        -0.978  -0.945  -0.983  -0.777  -0.715  -0.789  -0.892  -0.852  -0.873
291   R        -1.525  -1.520  -1.458  -1.224  -1.213  -1.119  -1.194  -1.187  -1.098
292   M        -1.525  -1.520  -1.458  -1.504  -1.510  -1.398  -1.194  -1.187  -1.098
293   L        -0.432  -0.430  -0.423  -0.627  -0.617  -0.574  -0.590  -0.584  -0.558
294   S        -0.226  -0.209  -0.302  -0.152  -0.120  -0.281  -0.287  -0.263  -0.388
295   I        -0.978  -0.945  -0.983  -0.995  -0.940  -0.996  -0.892  -0.852  -0.873
296   P        -1.525  -1.520  -1.458  -1.389  -1.394  -1.283  -1.194  -1.187  -1.098
297   L        -0.978  -0.973  -0.959  -0.996  -0.986  -0.948  -0.892  -0.883  -0.847
298   L        -0.978  -0.985  -0.979  -1.028  -1.035  -1.042  -0.892  -0.897  -0.869
299   R         1.647   1.652   1.703   1.791   1.801   1.882   1.829   1.836   1.912
300   H        -0.226  -0.266  -0.348  -0.002  -0.060  -0.229  -0.287  -0.341  -0.452
301   I         1.647   1.652   1.703   1.628   1.633   1.720   1.829   1.836   1.912
302   L         0.661   0.647   0.536   0.535   0.514   0.339   0.620   0.597   0.390
303   G         1.647   1.652   1.703   1.773   1.784   1.864   1.829   1.836   1.912
304   T        -0.432  -0.438  -0.408  -0.611  -0.614  -0.570  -0.590  -0.593  -0.540
305   E         0.321   0.310   0.357   0.058   0.033   0.114   0.015  -0.007   0.059
306   Y         0.321   0.310   0.357   0.097   0.066   0.134   0.015  -0.007   0.059
307   G        -0.226  -0.266  -0.348  -0.103  -0.165  -0.321  -0.287  -0.341  -0.452
308   N         1.647   1.652   1.703   1.686   1.694   1.778   1.829   1.836   1.912
309   A         0.661   0.657   0.534   0.851   0.847   0.638   0.620   0.614   0.386
310   F         1.647   1.652   1.703   1.674   1.682   1.766   1.829   1.836   1.912
311   G         1.647   1.652   1.703   1.773   1.784   1.864   1.829   1.836   1.912
312   L         0.661   0.700   0.543   0.627   0.684   0.425   0.620   0.683   0.403
313   W         1.647   1.652   1.703   1.899   1.908   1.990   1.829   1.836   1.912
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   Q         0.321   0.317   0.354   0.194   0.182   0.225   0.015   0.008   0.054
316   E        -1.525  -1.520  -1.458  -1.356  -1.339  -1.250  -1.194  -1.187  -1.098
317   G        -0.978  -0.980  -0.959  -0.941  -0.947  -0.914  -0.892  -0.892  -0.847
318   E        -0.226  -0.266  -0.348  -0.260  -0.326  -0.447  -0.287  -0.341  -0.452
319   A        -0.978  -1.005  -0.988  -0.781  -0.826  -0.807  -0.892  -0.919  -0.878
320   S        -0.978  -0.982  -0.959  -0.901  -0.901  -0.858  -0.892  -0.893  -0.847
321   D         0.321   0.310   0.357   0.135   0.104   0.176   0.015  -0.007   0.059
322   S        -0.432  -0.446  -0.410  -0.588  -0.608  -0.547  -0.590  -0.602  -0.542
323   R         0.321   0.310   0.357   0.173   0.148   0.211   0.015  -0.007   0.059
324   E         0.661   0.627   0.530   0.630   0.578   0.437   0.620   0.563   0.380
325   Y         0.661   0.647   0.536   0.776   0.756   0.578   0.620   0.597   0.390
326   F         0.321   0.317   0.354   0.041   0.030   0.074   0.015   0.008   0.054
327   G         1.647   1.652   1.703   1.773   1.784   1.864   1.829   1.836   1.912
328   Y         0.321   0.310   0.357   0.192   0.166   0.239   0.015  -0.007   0.059
329   W        -0.978  -1.005  -0.988  -0.607  -0.646  -0.622  -0.892  -0.919  -0.878
330   V         0.661   0.627   0.530   0.774   0.728   0.559   0.620   0.563   0.380
331   F        -0.432  -0.430  -0.423  -0.435  -0.426  -0.393  -0.590  -0.584  -0.558
332   P         1.647   1.652   1.703   1.829   1.837   1.920   1.829   1.836   1.912
333   E        -0.432  -0.412  -0.418  -0.714  -0.683  -0.691  -0.590  -0.564  -0.552
334   A         1.647   1.652   1.703   1.829   1.838   1.920   1.829   1.836   1.912
335   S         1.647   1.652   1.703   1.610   1.619   1.702   1.829   1.836   1.912
336   Y         0.321   0.310   0.357   0.192   0.166   0.239   0.015  -0.007   0.059
337   F         1.647   1.652   1.703   1.674   1.682   1.766   1.829   1.836   1.912
338   N         1.647   1.652   1.703   1.686   1.694   1.778   1.829   1.836   1.912
339   H         1.647   1.652   1.703   1.881   1.897   1.972   1.829   1.836   1.912
340   S         1.647   1.652   1.703   1.610   1.619   1.702   1.829   1.836   1.912
341   C         1.647   1.652   1.703   1.802   1.812   1.894   1.829   1.836   1.912
342   N        -0.978  -0.971  -0.956  -0.909  -0.895  -0.877  -0.892  -0.881  -0.843
343   P         1.647   1.652   1.703   1.829   1.837   1.920   1.829   1.836   1.912
344   N         1.647   1.652   1.703   1.686   1.694   1.778   1.829   1.836   1.912
345   I        -0.226  -0.258  -0.322  -0.262  -0.319  -0.429  -0.287  -0.330  -0.416
346   T        -0.432  -0.430  -0.423  -0.509  -0.499  -0.499  -0.590  -0.584  -0.558
347   K         1.647   1.652   1.703   1.558   1.573   1.650   1.829   1.836   1.912
348   Y        -0.226  -0.201  -0.309  -0.168  -0.125  -0.314  -0.287  -0.251  -0.398
349   R         1.647   1.652   1.703   1.791   1.801   1.882   1.829   1.836   1.912
350   K        -1.525  -1.520  -1.458  -1.568  -1.559  -1.462  -1.194  -1.187  -1.098
351   G        -0.978  -0.973  -0.959  -0.898  -0.891  -0.876  -0.892  -0.883  -0.847
352   N        -0.978  -0.985  -0.979  -0.868  -0.880  -0.884  -0.892  -0.897  -0.869
353   S        -1.525  -1.520  -1.458  -1.563  -1.545  -1.457  -1.194  -1.187  -1.098
354   M        -0.226  -0.258  -0.322  -0.039  -0.093  -0.231  -0.287  -0.330  -0.416
355   L        -0.978  -0.980  -0.959  -0.898  -0.890  -0.872  -0.892  -0.892  -0.847
356   F         0.661   0.657   0.534   0.729   0.724   0.538   0.620   0.614   0.386
357   T        -0.226  -0.258  -0.322  -0.129  -0.175  -0.286  -0.287  -0.330  -0.416
358   M        -0.978  -0.985  -0.979  -0.936  -0.942  -0.902  -0.892  -0.897  -0.869
359   N        -0.978  -1.005  -0.988  -1.000  -1.051  -1.029  -0.892  -0.919  -0.878
360   R        -0.432  -0.430  -0.423  -0.536  -0.534  -0.512  -0.590  -0.584  -0.558
361   D         1.647   1.652   1.703   1.737   1.745   1.829   1.829   1.836   1.912
362   I         0.321   0.331   0.367   0.140   0.158   0.215   0.015   0.034   0.080
363   K        -1.525  -1.520  -1.458  -1.402  -1.394  -1.296  -1.194  -1.187  -1.098
364   K        -0.978  -0.987  -0.978  -0.964  -0.973  -0.943  -0.892  -0.899  -0.867
365   D        -0.226  -0.225  -0.310  -0.073  -0.071  -0.212  -0.287  -0.285  -0.399
366   E         0.661   0.627   0.530   0.624   0.572   0.427   0.620   0.563   0.380
367   Q         0.661   0.700   0.543   0.648   0.698   0.484   0.620   0.683   0.403
368   I         0.661   0.700   0.543   0.535   0.592   0.352   0.620   0.683   0.403
369   C        -0.226  -0.227  -0.309  -0.065  -0.068  -0.211  -0.287  -0.289  -0.398
370   I         1.647   1.652   1.703   1.628   1.633   1.720   1.829   1.836   1.912
371   D         0.321   0.310   0.357   0.156   0.129   0.199   0.015  -0.007   0.059
372   Y         1.647   1.652   1.703   1.737   1.745   1.829   1.829   1.836   1.912
373   S        -0.432  -0.430  -0.423  -0.568  -0.554  -0.556  -0.590  -0.584  -0.558
374   G         0.321   0.310   0.357   0.229   0.205   0.276   0.015  -0.007   0.059
375   V        -0.432  -0.430  -0.423  -0.473  -0.468  -0.459  -0.590  -0.584  -0.558
376   L        -0.226  -0.266  -0.348  -0.359  -0.420  -0.552  -0.287  -0.341  -0.452
377   D        -0.226  -0.258  -0.322  -0.061  -0.108  -0.204  -0.287  -0.330  -0.416
378   L         0.321   0.310   0.357  -0.069  -0.095  -0.016   0.015  -0.007   0.059
379   P        -0.226  -0.258  -0.322  -0.021  -0.073  -0.185  -0.287  -0.330  -0.416
380   T         0.661   0.700   0.543   0.794   0.857   0.613   0.620   0.683   0.403
381   V        -1.525  -1.520  -1.458  -1.381  -1.375  -1.275  -1.194  -1.187  -1.098
382   K        -0.978  -0.985  -0.979  -1.008  -1.021  -1.045  -0.892  -0.897  -0.869
383   R         1.647   1.652   1.703   1.791   1.801   1.882   1.829   1.836   1.912
384   R         0.321   0.332   0.368   0.315   0.339   0.388   0.015   0.036   0.080
385   A        -0.432  -0.447  -0.407  -0.558  -0.581  -0.527  -0.590  -0.604  -0.539
386   F        -0.432  -0.430  -0.423  -0.475  -0.467  -0.459  -0.590  -0.584  -0.558
387   L         1.647   1.652   1.703   1.505   1.514   1.597   1.829   1.836   1.912
388   A        -0.226  -0.169  -0.314  -0.249  -0.160  -0.373  -0.287  -0.207  -0.405
389   D         0.321   0.332   0.368   0.088   0.103   0.165   0.015   0.036   0.080
390   S         0.392   0.408   0.388   0.246   0.277   0.216   0.149   0.178   0.118
391   W         1.647   1.652   1.703   1.899   1.908   1.990   1.829   1.836   1.912
392   F         1.647   1.652   1.703   1.674   1.682   1.766   1.829   1.836   1.912
393   F         1.647   1.652   1.703   1.674   1.682   1.766   1.829   1.836   1.912
394   D        -0.978  -0.982  -0.959  -0.923  -0.933  -0.899  -0.892  -0.893  -0.847
395   C         1.647   1.652   1.703   1.802   1.812   1.894   1.829   1.836   1.912
396   A        -0.978  -0.982  -0.959  -0.915  -0.927  -0.902  -0.892  -0.893  -0.847
397   C         1.647   1.652   1.703   1.802   1.812   1.894   1.829   1.836   1.912
398   E        -0.978  -0.945  -0.983  -1.000  -0.940  -1.026  -0.892  -0.852  -0.873
399   R         0.321   0.310   0.357   0.173   0.148   0.211   0.015  -0.007   0.059
400   C         1.647   1.652   1.703   1.802   1.812   1.894   1.829   1.836   1.912
401   K        -1.525  -1.520  -1.458  -1.572  -1.560  -1.465  -1.194  -1.187  -1.098
402   S         0.321   0.310   0.357   0.105   0.088   0.161   0.015  -0.007   0.059
403   E         0.661   0.696   0.540   0.630   0.676   0.454   0.620   0.678   0.398
404   L         1.647   1.652   1.703   1.505   1.514   1.597   1.829   1.836   1.912
405   Q        -0.402  -0.399  -0.387  -0.475  -0.468  -0.441  -0.533  -0.528  -0.506
406   S        -1.085  -1.082  -1.020  -1.127  -1.117  -1.023  -1.005  -0.999  -0.910
407   V        -0.402  -0.409  -0.419  -0.443  -0.455  -0.498  -0.533  -0.541  -0.550
408   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
409   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
410   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
411   H         0.392   0.334   0.378   0.430   0.303   0.363   0.149   0.040   0.100
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12529
Output conservation file - output/Q12529
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
