1     M         1.680   1.684   1.737   1.935   1.943   2.020   1.832   1.838   1.918
2     K        -0.556  -0.483  -0.521  -0.421  -0.297  -0.378  -0.635  -0.536  -0.582
3     F        -1.301  -1.286  -1.200  -1.285  -1.245  -1.130  -1.128  -1.112  -0.995
4     S         0.311   0.322   0.313   0.198   0.221   0.208   0.078   0.098   0.057
5     S        -0.682  -0.682  -0.590  -0.937  -0.939  -0.790  -0.799  -0.797  -0.672
6     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     K        -0.589  -0.598  -0.562  -0.715  -0.710  -0.644  -0.694  -0.703  -0.638
8     S        -0.589  -0.602  -0.542  -0.761  -0.770  -0.668  -0.694  -0.707  -0.615
9     I        -0.364  -0.365  -0.446  -0.247  -0.253  -0.404  -0.378  -0.379  -0.483
10    I        -0.589  -0.577  -0.559  -0.700  -0.694  -0.633  -0.694  -0.681  -0.634
11    F        -0.589  -0.576  -0.534  -0.756  -0.740  -0.663  -0.694  -0.680  -0.606
12    A        -0.589  -0.599  -0.536  -0.673  -0.692  -0.591  -0.694  -0.704  -0.609
13    T        -1.185  -1.188  -1.161  -1.169  -1.183  -1.134  -1.010  -1.012  -0.958
14    I        -1.185  -1.172  -1.173  -1.128  -1.102  -1.141  -1.010  -0.994  -0.970
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    A        -1.185  -1.209  -1.168  -1.260  -1.292  -1.228  -1.010  -1.034  -0.964
33    S        -0.364  -0.385  -0.490  -0.469  -0.495  -0.682  -0.378  -0.405  -0.542
34    L        -1.781  -1.783  -1.673  -1.703  -1.715  -1.539  -1.326  -1.325  -1.189
35    A        -0.589  -0.589  -0.541  -0.767  -0.765  -0.665  -0.694  -0.693  -0.614
36    L        -1.185  -1.175  -1.137  -1.318  -1.304  -1.244  -1.010  -0.998  -0.933
37    S         0.604   0.585   0.448   0.527   0.500   0.275   0.569   0.540   0.295
38    A        -0.364  -0.324  -0.463  -0.447  -0.384  -0.621  -0.378  -0.325  -0.506
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    P         1.680   1.684   1.737   1.846   1.859   1.932   1.832   1.838   1.918
51    V        -0.556  -0.505  -0.522  -0.732  -0.651  -0.683  -0.635  -0.566  -0.584
52    T        -0.556  -0.505  -0.522  -0.665  -0.588  -0.608  -0.635  -0.566  -0.584
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    Y        -1.301  -1.286  -1.200  -1.333  -1.326  -1.177  -1.128  -1.112  -0.995
57    D        -1.301  -1.286  -1.200  -1.297  -1.300  -1.142  -1.128  -1.112  -0.995
58    T        -0.556  -0.505  -0.522  -0.628  -0.530  -0.594  -0.635  -0.566  -0.584
59    N         0.471   0.358   0.367   0.431   0.249   0.249   0.352   0.160   0.153
60    S        -1.185  -1.187  -1.160  -1.082  -1.085  -1.017  -1.010  -1.010  -0.956
61    T        -0.364  -0.324  -0.463  -0.419  -0.353  -0.602  -0.378  -0.325  -0.506
62    A        -0.589  -0.598  -0.562  -0.795  -0.813  -0.752  -0.694  -0.703  -0.638
63    E        -0.589  -0.576  -0.558  -0.697  -0.678  -0.648  -0.694  -0.680  -0.633
64    L        -1.185  -1.187  -1.160  -1.030  -1.035  -0.956  -1.010  -1.010  -0.956
65    Q        -1.185  -1.185  -1.135  -0.922  -0.925  -0.846  -1.010  -1.008  -0.931
66    S        -1.185  -1.172  -1.173  -1.025  -1.011  -1.008  -1.010  -0.994  -0.970
67    P        -0.364  -0.361  -0.462  -0.234  -0.234  -0.366  -0.378  -0.374  -0.504
68    S        -0.589  -0.602  -0.543  -0.861  -0.879  -0.785  -0.694  -0.706  -0.616
69    S        -0.364  -0.324  -0.463  -0.383  -0.319  -0.521  -0.378  -0.325  -0.506
70    Q        -1.185  -1.197  -1.136  -1.030  -1.037  -0.937  -1.010  -1.021  -0.932
71    E        -0.589  -0.577  -0.559  -0.688  -0.672  -0.638  -0.694  -0.681  -0.634
72    I        -1.781  -1.783  -1.673  -1.607  -1.618  -1.446  -1.326  -1.325  -1.189
73    L        -1.185  -1.172  -1.173  -1.181  -1.162  -1.189  -1.010  -0.994  -0.970
74    G         0.233   0.226   0.289  -0.027  -0.046   0.060  -0.062  -0.074   0.013
75    W         1.680   1.684   1.737   1.931   1.939   2.015   1.832   1.838   1.918
76    S        -1.185  -1.175  -1.137  -1.207  -1.183  -1.127  -1.010  -0.998  -0.933
77    H        -1.781  -1.783  -1.673  -1.617  -1.610  -1.455  -1.326  -1.325  -1.189
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    A        -0.589  -0.598  -0.562  -0.481  -0.492  -0.455  -0.694  -0.703  -0.638
82    T        -1.185  -1.188  -1.161  -1.179  -1.187  -1.145  -1.010  -1.012  -0.958
83    F         1.680   1.684   1.737   1.742   1.748   1.830   1.832   1.838   1.918
84    P         1.680   1.684   1.737   1.846   1.859   1.932   1.832   1.838   1.918
85    T        -0.682  -0.682  -0.590  -0.712  -0.726  -0.570  -0.799  -0.797  -0.672
86    I        -1.185  -1.161  -1.133  -0.982  -0.950  -0.910  -1.010  -0.983  -0.928
87    Y        -0.364  -0.401  -0.452  -0.100  -0.162  -0.262  -0.378  -0.427  -0.491
88    Q        -1.185  -1.187  -1.160  -0.938  -0.938  -0.928  -1.010  -1.010  -0.956
89    T         0.604   0.585   0.448   0.513   0.496   0.274   0.569   0.540   0.295
90    C         1.680   1.684   1.737   1.864   1.871   1.950   1.832   1.838   1.918
91    N         1.680   1.684   1.737   1.668   1.683   1.758   1.832   1.838   1.918
92    E        -1.185  -1.184  -1.138  -1.134  -1.137  -1.055  -1.010  -1.007  -0.934
93    T         0.604   0.606   0.454   0.570   0.577   0.325   0.569   0.573   0.305
94    N         0.233   0.226   0.289   0.169   0.164   0.260  -0.062  -0.074   0.013
95    A        -1.185  -1.209  -1.168  -0.946  -0.994  -0.951  -1.010  -1.034  -0.964
96    R         0.233   0.226   0.289   0.196   0.183   0.271  -0.062  -0.074   0.013
97    M         0.233   0.226   0.289   0.391   0.377   0.468  -0.062  -0.074   0.013
98    L         0.604   0.631   0.450   0.533   0.567   0.321   0.569   0.613   0.299
99    N         0.233   0.235   0.289  -0.062  -0.048   0.029  -0.062  -0.058   0.014
100   A        -1.781  -1.783  -1.673  -1.844  -1.841  -1.677  -1.326  -1.325  -1.189
101   A         0.233   0.233   0.281  -0.078  -0.083  -0.006  -0.062  -0.063  -0.001
102   F         0.604   0.585   0.448   0.527   0.498   0.308   0.569   0.540   0.295
103   K        -1.185  -1.187  -1.160  -0.846  -0.843  -0.811  -1.010  -1.010  -0.956
104   D         0.233   0.226   0.289   0.074   0.060   0.161  -0.062  -0.074   0.013
105   T         0.604   0.579   0.455   0.578   0.542   0.340   0.569   0.529   0.307
106   A        -0.589  -0.598  -0.562  -0.667  -0.680  -0.634  -0.694  -0.703  -0.638
107   E        -0.364  -0.385  -0.490  -0.239  -0.273  -0.461  -0.378  -0.405  -0.542
108   I        -0.589  -0.598  -0.562  -0.723  -0.747  -0.655  -0.694  -0.703  -0.638
109   T        -0.589  -0.576  -0.558  -0.835  -0.815  -0.784  -0.694  -0.680  -0.633
110   A        -0.364  -0.365  -0.446  -0.404  -0.403  -0.536  -0.378  -0.379  -0.483
111   Y        -1.185  -1.172  -1.173  -0.895  -0.879  -0.904  -1.010  -0.994  -0.970
112   G         0.604   0.585   0.448   0.541   0.512   0.297   0.569   0.540   0.295
113   K         0.604   0.585   0.448   0.859   0.834   0.629   0.569   0.540   0.295
114   D         1.680   1.684   1.737   1.644   1.648   1.735   1.832   1.838   1.918
115   R        -0.589  -0.577  -0.559  -0.367  -0.353  -0.314  -0.694  -0.681  -0.634
116   L         0.233   0.226   0.289  -0.112  -0.128  -0.023  -0.062  -0.074   0.013
117   L         0.604   0.606   0.454   0.483   0.482   0.249   0.569   0.573   0.305
118   N        -0.589  -0.598  -0.562  -0.623  -0.632  -0.579  -0.694  -0.703  -0.638
119   Y        -0.589  -0.598  -0.562  -0.615  -0.624  -0.566  -0.694  -0.703  -0.638
120   G         1.680   1.684   1.737   1.593   1.597   1.685   1.832   1.838   1.918
121   V        -1.185  -1.209  -1.168  -1.203  -1.239  -1.182  -1.010  -1.034  -0.964
122   D        -1.301  -1.301  -1.200  -1.381  -1.364  -1.224  -1.128  -1.127  -0.995
123   D         0.233   0.226   0.289  -0.045  -0.059   0.035  -0.062  -0.074   0.013
124   V        -1.781  -1.783  -1.673  -1.348  -1.349  -1.192  -1.326  -1.325  -1.189
125   Y        -0.364  -0.360  -0.464  -0.186  -0.184  -0.345  -0.378  -0.372  -0.508
126   Y         0.233   0.233   0.281   0.113   0.110   0.185  -0.062  -0.063  -0.001
127   K        -0.364  -0.385  -0.490  -0.041  -0.066  -0.220  -0.378  -0.405  -0.542
128   R         0.233   0.226   0.289   0.277   0.267   0.357  -0.062  -0.074   0.013
129   W         0.233   0.226   0.289   0.289   0.273   0.359  -0.062  -0.074   0.013
130   F         1.680   1.684   1.737   1.742   1.748   1.830   1.832   1.838   1.918
131   G         1.680   1.684   1.737   1.593   1.597   1.685   1.832   1.838   1.918
132   N         0.604   0.631   0.450   0.652   0.698   0.413   0.569   0.613   0.299
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   G        -1.185  -1.198  -1.138  -1.312  -1.334  -1.247  -1.010  -1.022  -0.934
135   S        -0.589  -0.602  -0.543  -0.673  -0.690  -0.592  -0.694  -0.707  -0.616
136   I        -1.185  -1.172  -1.173  -1.233  -1.209  -1.205  -1.010  -0.994  -0.970
137   F        -0.364  -0.385  -0.490  -0.276  -0.316  -0.515  -0.378  -0.405  -0.542
138   T         0.233   0.226   0.289   0.046   0.037   0.135  -0.062  -0.074   0.013
139   V         1.680   1.684   1.737   1.700   1.704   1.790   1.832   1.838   1.918
140   M        -1.185  -1.172  -1.173  -0.977  -0.959  -0.952  -1.010  -0.994  -0.970
141   G         1.680   1.684   1.737   1.593   1.597   1.685   1.832   1.838   1.918
142   V        -1.185  -1.188  -1.161  -0.918  -0.923  -0.870  -1.010  -1.012  -0.958
143   F        -0.364  -0.324  -0.463  -0.239  -0.182  -0.413  -0.378  -0.325  -0.506
144   E         1.680   1.684   1.737   1.742   1.753   1.830   1.832   1.838   1.918
145   Q        -0.364  -0.361  -0.462  -0.220  -0.209  -0.357  -0.378  -0.374  -0.504
146   L        -1.185  -1.184  -1.138  -1.132  -1.138  -1.072  -1.010  -1.007  -0.934
147   M        -0.589  -0.598  -0.562  -0.491  -0.507  -0.418  -0.694  -0.703  -0.638
148   E        -1.185  -1.187  -1.160  -1.051  -1.057  -1.027  -1.010  -1.010  -0.956
149   A        -0.589  -0.575  -0.533  -0.870  -0.848  -0.774  -0.694  -0.679  -0.605
150   S        -1.185  -1.172  -1.173  -1.207  -1.192  -1.206  -1.010  -0.994  -0.970
151   K         1.680   1.684   1.737   1.814   1.829   1.902   1.832   1.838   1.918
152   G        -0.364  -0.360  -0.464  -0.450  -0.440  -0.613  -0.378  -0.372  -0.508
153   A        -1.185  -1.209  -1.168  -1.167  -1.210  -1.149  -1.010  -1.034  -0.964
154   M        -1.781  -1.783  -1.673  -1.544  -1.543  -1.383  -1.326  -1.325  -1.189
155   L         1.680   1.684   1.737   1.517   1.521   1.611   1.832   1.838   1.918
156   M        -0.364  -0.361  -0.462  -0.132  -0.129  -0.270  -0.378  -0.374  -0.504
157   R         0.604   0.579   0.455   0.788   0.748   0.531   0.569   0.529   0.307
158   C         1.680   1.684   1.737   1.864   1.871   1.950   1.832   1.838   1.918
159   D         1.680   1.684   1.737   1.644   1.648   1.735   1.832   1.838   1.918
160   D         1.680   1.684   1.737   1.644   1.648   1.735   1.832   1.838   1.918
161   I        -0.589  -0.602  -0.543  -0.533  -0.557  -0.478  -0.694  -0.706  -0.616
162   D        -0.364  -0.324  -0.463  -0.289  -0.234  -0.441  -0.378  -0.325  -0.506
163   G         0.233   0.226   0.289  -0.027  -0.046   0.060  -0.062  -0.074   0.013
164   L        -1.781  -1.783  -1.673  -1.698  -1.698  -1.534  -1.326  -1.325  -1.189
165   C         1.680   1.684   1.737   1.864   1.871   1.950   1.832   1.838   1.918
166   A         0.233   0.226   0.289   0.053   0.045   0.147  -0.062  -0.074   0.013
167   A        -1.185  -1.188  -1.161  -1.247  -1.257  -1.213  -1.010  -1.012  -0.958
168   N        -0.589  -0.577  -0.559  -0.618  -0.606  -0.540  -0.694  -0.681  -0.634
169   P         0.311   0.322   0.313   0.284   0.312   0.251   0.078   0.098   0.057
170   N         0.311   0.288   0.306   0.104   0.061   0.085   0.078   0.036   0.045
171   Y        -1.185  -1.172  -1.173  -1.233  -1.213  -1.221  -1.010  -0.994  -0.970
172   Y         0.604   0.585   0.448   0.921   0.895   0.668   0.569   0.540   0.295
173   A        -0.364  -0.324  -0.463  -0.243  -0.193  -0.349  -0.378  -0.325  -0.506
174   G         1.680   1.684   1.737   1.593   1.597   1.685   1.832   1.838   1.918
175   H         0.233   0.228   0.279   0.188   0.180   0.266  -0.062  -0.071  -0.004
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   H         0.233   0.226   0.289   0.320   0.305   0.399  -0.062  -0.074   0.013
178   R        -0.589  -0.598  -0.562  -0.644  -0.664  -0.572  -0.694  -0.703  -0.638
179   Q        -1.781  -1.783  -1.673  -1.673  -1.668  -1.510  -1.326  -1.325  -1.189
180   S         0.604   0.585   0.448   0.625   0.608   0.367   0.569   0.540   0.295
181   A        -0.589  -0.602  -0.543  -0.710  -0.727  -0.612  -0.694  -0.706  -0.616
182   P        -0.364  -0.401  -0.452  -0.329  -0.380  -0.463  -0.378  -0.427  -0.491
183   A        -1.185  -1.209  -1.168  -1.229  -1.274  -1.207  -1.010  -1.034  -0.964
184   E         0.604   0.579   0.455   0.781   0.751   0.577   0.569   0.529   0.307
185   T         0.604   0.606   0.454   0.602   0.609   0.376   0.569   0.573   0.305
186   V        -0.589  -0.602  -0.543  -0.618  -0.633  -0.532  -0.694  -0.706  -0.616
187   I         0.604   0.631   0.450   0.771   0.808   0.539   0.569   0.613   0.299
188   C         1.680   1.684   1.737   1.864   1.871   1.950   1.832   1.838   1.918
189   D         1.680   1.684   1.737   1.644   1.648   1.735   1.832   1.838   1.918
190   Y         0.604   0.585   0.448   0.514   0.485   0.288   0.569   0.540   0.295
191   F         0.233   0.226   0.289   0.041   0.028   0.115  -0.062  -0.074   0.013
192   Y         0.604   0.579   0.455   0.699   0.663   0.480   0.569   0.529   0.307
193   T        -1.185  -1.175  -1.137  -1.114  -1.100  -1.038  -1.010  -0.998  -0.933
194   S        -0.589  -0.576  -0.535  -0.838  -0.816  -0.748  -0.694  -0.680  -0.608
195   K         0.233   0.226   0.289   0.271   0.263   0.353  -0.062  -0.074   0.013
196   K        -0.364  -0.385  -0.490  -0.147  -0.174  -0.369  -0.378  -0.405  -0.542
197   P         0.233   0.226   0.289   0.217   0.205   0.292  -0.062  -0.074   0.013
198   L         1.680   1.684   1.737   1.517   1.521   1.611   1.832   1.838   1.918
199   S        -0.364  -0.343  -0.447  -0.469  -0.429  -0.609  -0.378  -0.350  -0.485
200   T        -0.589  -0.576  -0.558  -0.497  -0.482  -0.434  -0.694  -0.680  -0.633
201   I        -0.364  -0.385  -0.490  -0.163  -0.201  -0.366  -0.378  -0.405  -0.542
202   C         1.680   1.684   1.737   1.864   1.871   1.950   1.832   1.838   1.918
203   F         0.233   0.226   0.289   0.041   0.028   0.115  -0.062  -0.074   0.013
204   E        -0.364  -0.385  -0.490  -0.181  -0.214  -0.381  -0.378  -0.405  -0.542
205   G         1.680   1.684   1.737   1.593   1.597   1.685   1.832   1.838   1.918
206   T        -0.589  -0.577  -0.559  -0.707  -0.692  -0.654  -0.694  -0.681  -0.634
207   I         0.233   0.226   0.289   0.103   0.087   0.179  -0.062  -0.074   0.013
208   V         1.680   1.684   1.737   1.700   1.704   1.790   1.832   1.838   1.918
209   D        -0.589  -0.598  -0.562  -0.723  -0.736  -0.671  -0.694  -0.703  -0.638
210   V        -1.185  -1.188  -1.161  -1.087  -1.088  -1.061  -1.010  -1.012  -0.958
211   G         0.233   0.226   0.289  -0.090  -0.103  -0.008  -0.062  -0.074   0.013
212   P         0.233   0.226   0.289   0.285   0.279   0.364  -0.062  -0.074   0.013
213   K        -0.589  -0.589  -0.541  -0.610  -0.604  -0.538  -0.694  -0.693  -0.614
214   H        -1.185  -1.187  -1.160  -1.057  -1.056  -1.064  -1.010  -1.010  -0.956
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   Y         0.233   0.226   0.289   0.113   0.099   0.198  -0.062  -0.074   0.013
217   A        -0.589  -0.577  -0.559  -0.600  -0.578  -0.573  -0.694  -0.681  -0.634
218   G         0.233   0.226   0.289  -0.071  -0.089   0.013  -0.062  -0.074   0.013
219   I         0.233   0.226   0.289   0.092   0.073   0.168  -0.062  -0.074   0.013
220   D         1.680   1.684   1.737   1.644   1.648   1.735   1.832   1.838   1.918
221   M         0.604   0.585   0.448   0.578   0.551   0.388   0.569   0.540   0.295
222   L         0.233   0.249   0.295  -0.035  -0.015   0.069  -0.062  -0.033   0.025
223   H         1.680   1.684   1.737   1.873   1.880   1.959   1.832   1.838   1.918
224   R         1.680   1.684   1.737   1.837   1.843   1.924   1.832   1.838   1.918
225   Y        -0.589  -0.589  -0.543  -0.573  -0.577  -0.489  -0.694  -0.693  -0.616
226   L        -0.589  -0.576  -0.558  -0.565  -0.550  -0.516  -0.694  -0.680  -0.633
227   H         1.680   1.684   1.737   1.873   1.880   1.959   1.832   1.838   1.918
228   V        -0.364  -0.380  -0.454  -0.444  -0.473  -0.581  -0.378  -0.398  -0.494
229   P        -0.364  -0.401  -0.452  -0.211  -0.263  -0.322  -0.378  -0.427  -0.491
230   T        -1.185  -1.172  -1.173  -1.159  -1.136  -1.118  -1.010  -0.994  -0.970
231   M        -0.589  -0.577  -0.559  -0.470  -0.457  -0.441  -0.694  -0.681  -0.634
232   S         0.311   0.322   0.313   0.111   0.136   0.103   0.078   0.098   0.057
233   M        -0.364  -0.360  -0.464  -0.317  -0.309  -0.460  -0.378  -0.372  -0.508
234   D        -1.185  -1.172  -1.173  -0.926  -0.905  -0.939  -1.010  -0.994  -0.970
235   G         0.604   0.579   0.455   0.546   0.504   0.302   0.569   0.529   0.307
236   Y        -0.589  -0.577  -0.559  -0.610  -0.600  -0.550  -0.694  -0.681  -0.634
237   V         0.233   0.228   0.279   0.152   0.138   0.213  -0.062  -0.071  -0.004
238   G        -0.364  -0.366  -0.449  -0.382  -0.384  -0.520  -0.378  -0.381  -0.488
239   E         0.233   0.226   0.289   0.231   0.222   0.318  -0.062  -0.074   0.013
240   Y         0.604   0.629   0.453   0.746   0.779   0.550   0.569   0.609   0.304
241   A         0.233   0.249   0.295  -0.066  -0.038   0.032  -0.062  -0.033   0.025
242   E         0.233   0.226   0.289   0.101   0.087   0.180  -0.062  -0.074   0.013
243   T         0.604   0.631   0.450   0.621   0.661   0.399   0.569   0.613   0.299
244   L         0.233   0.226   0.289  -0.065  -0.081   0.027  -0.062  -0.074   0.013
245   E        -0.589  -0.576  -0.534  -0.576  -0.560  -0.476  -0.694  -0.680  -0.606
246   E         0.604   0.631   0.450   0.725   0.767   0.481   0.569   0.613   0.299
247   V        -0.364  -0.343  -0.447  -0.170  -0.146  -0.283  -0.378  -0.350  -0.485
248   V         0.604   0.585   0.448   0.517   0.486   0.292   0.569   0.540   0.295
249   D        -1.185  -1.172  -1.173  -1.093  -1.072  -1.100  -1.010  -0.994  -0.970
250   Y         0.604   0.585   0.448   0.514   0.485   0.288   0.569   0.540   0.295
251   T         0.604   0.585   0.448   0.546   0.518   0.305   0.569   0.540   0.295
252   Q        -0.364  -0.345  -0.443  -0.027  -0.000  -0.153  -0.378  -0.352  -0.479
253   N        -0.364  -0.385  -0.490  -0.223  -0.244  -0.402  -0.378  -0.405  -0.542
254   N         1.680   1.684   1.737   1.668   1.683   1.758   1.832   1.838   1.918
255   A         0.604   0.579   0.455   0.527   0.491   0.287   0.569   0.529   0.307
256   T         1.680   1.684   1.737   1.612   1.621   1.703   1.832   1.838   1.918
257   Y        -0.364  -0.345  -0.443  -0.224  -0.197  -0.343  -0.378  -0.352  -0.479
258   A         1.680   1.684   1.737   1.569   1.575   1.662   1.832   1.838   1.918
259   V         0.604   0.629   0.453   0.666   0.699   0.419   0.569   0.609   0.304
260   R         1.680   1.684   1.737   1.837   1.843   1.924   1.832   1.838   1.918
261   N         1.680   1.684   1.737   1.668   1.683   1.758   1.832   1.838   1.918
262   T        -0.589  -0.576  -0.558  -0.798  -0.779  -0.728  -0.694  -0.680  -0.633
263   D        -0.364  -0.385  -0.490  -0.346  -0.381  -0.563  -0.378  -0.405  -0.542
264   N        -0.364  -0.385  -0.490  -0.352  -0.377  -0.584  -0.378  -0.405  -0.542
265   Y         0.233   0.226   0.289  -0.015  -0.034   0.062  -0.062  -0.074   0.013
266   L        -0.364  -0.385  -0.490  -0.349  -0.384  -0.503  -0.378  -0.405  -0.542
267   Y         1.680   1.684   1.737   1.691   1.699   1.781   1.832   1.838   1.918
268   Y         1.680   1.684   1.737   1.691   1.699   1.781   1.832   1.838   1.918
269   L         0.233   0.226   0.289  -0.137  -0.156  -0.050  -0.062  -0.074   0.013
270   A         0.233   0.226   0.289  -0.122  -0.141  -0.039  -0.062  -0.074   0.013
271   D         1.680   1.684   1.737   1.644   1.648   1.735   1.832   1.838   1.918
272   V         1.680   1.684   1.737   1.700   1.704   1.790   1.832   1.838   1.918
273   Y         1.680   1.684   1.737   1.691   1.699   1.781   1.832   1.838   1.918
274   S         0.604   0.585   0.448   0.527   0.500   0.275   0.569   0.540   0.295
275   A        -0.589  -0.576  -0.558  -0.702  -0.687  -0.638  -0.694  -0.680  -0.633
276   S        -1.185  -1.172  -1.173  -1.256  -1.235  -1.264  -1.010  -0.994  -0.970
277   V         0.604   0.606   0.454   0.713   0.713   0.495   0.569   0.573   0.305
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   I        -0.364  -0.345  -0.443  -0.191  -0.163  -0.326  -0.378  -0.352  -0.479
280   P         1.680   1.684   1.737   1.846   1.859   1.932   1.832   1.838   1.918
281   G         1.680   1.684   1.737   1.593   1.597   1.685   1.832   1.838   1.918
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   G         1.680   1.684   1.737   1.593   1.597   1.685   1.832   1.838   1.918
284   C         1.680   1.684   1.737   1.864   1.871   1.950   1.832   1.838   1.918
285   L        -0.364  -0.385  -0.490  -0.455  -0.488  -0.652  -0.378  -0.405  -0.542
286   G         1.680   1.684   1.737   1.593   1.597   1.685   1.832   1.838   1.918
287   N        -0.364  -0.361  -0.462  -0.291  -0.290  -0.442  -0.378  -0.374  -0.504
288   L        -0.364  -0.385  -0.490  -0.412  -0.448  -0.592  -0.378  -0.405  -0.542
289   -        -1.301  -1.302  -1.200  -1.253  -1.214  -1.099  -1.128  -1.128  -0.995
290   -        -0.556  -0.574  -0.560  -0.696  -0.646  -0.669  -0.635  -0.657  -0.633
291   -        -0.556  -0.559  -0.522  -0.600  -0.625  -0.554  -0.635  -0.637  -0.584
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12512
Output conservation file - output/Q12512
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
