1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     M         1.311   1.342   1.401   1.535   1.583   1.668   1.419   1.463   1.556
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     Y        -0.211  -0.245  -0.311  -0.230  -0.384  -0.462  -0.371  -0.451  -0.511
8     G         1.311   1.342   1.401   1.418   1.460   1.557   1.419   1.463   1.556
9     D         0.360   0.323   0.306   0.248   0.185   0.127   0.156   0.075  -0.002
10    L        -0.211  -0.327  -0.310  -0.500  -0.663  -0.603  -0.371  -0.521  -0.507
11    G        -0.211  -0.275  -0.301  -0.116  -0.218  -0.277  -0.371  -0.440  -0.493
12    N         0.674   0.622   0.452   0.754   0.688   0.364   0.682   0.597   0.277
13    K         1.311   1.342   1.401   1.364   1.420   1.506   1.419   1.463   1.556
14    L         1.311   1.342   1.401   1.009   1.057   1.167   1.419   1.463   1.556
15    V         0.192   0.222   0.283   0.065   0.116   0.185  -0.160  -0.118  -0.047
16    L        -0.504  -0.680  -0.768  -0.613  -0.851  -0.931  -0.476  -0.689  -0.783
17    E        -0.336  -0.265  -0.303  -0.515  -0.369  -0.401  -0.581  -0.458  -0.499
18    A         0.360   0.268   0.298   0.383   0.191   0.216   0.156  -0.029  -0.017
19    K         0.674   0.622   0.452   0.802   0.748   0.480   0.682   0.597   0.277
20    R         1.311   1.342   1.401   1.364   1.399   1.506   1.419   1.463   1.556
21    T         0.360   0.444   0.373   0.372   0.500   0.357   0.156   0.295   0.128
22    K        -0.740  -0.656  -0.761  -0.721  -0.591  -0.743  -0.792  -0.682  -0.777
23    Q        -0.812  -0.892  -0.804  -0.822  -0.902  -0.772  -0.897  -0.951  -0.828
24    L         1.311   1.342   1.401   1.009   1.057   1.167   1.419   1.463   1.556
25    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    V        -0.740  -0.665  -0.785  -0.755  -0.705  -0.849  -0.792  -0.734  -0.809
44    N        -2.205  -2.118  -1.985  -2.015  -1.913  -1.718  -1.529  -1.445  -1.287
45    L         0.067   0.182  -0.199  -0.098   0.055  -0.445   0.051   0.210  -0.339
46    P         1.311   1.342   1.401   1.517   1.555   1.652   1.419   1.463   1.556
47    M        -1.619  -1.507  -1.486  -1.396  -1.227  -1.232  -1.318  -1.206  -1.130
48    Y         1.311   1.342   1.401   1.418   1.463   1.557   1.419   1.463   1.556
49    H         0.360   0.507   0.384   0.360   0.577   0.393   0.156   0.404   0.148
50    E        -1.326  -1.311  -1.190  -1.380  -1.344  -1.166  -1.213  -1.174  -1.020
51    D         0.139   0.175   0.273  -0.213  -0.148   0.002  -0.265  -0.210  -0.068
52    I         0.067   0.041  -0.213  -0.098  -0.141  -0.466   0.051  -0.004  -0.360
53    I         0.674   0.806   0.477   0.814   0.983   0.535   0.682   0.877   0.322
54    R        -0.211  -0.268  -0.290  -0.175  -0.251  -0.307  -0.371  -0.429  -0.475
55    N        -1.326  -1.326  -1.197  -1.288  -1.293  -1.099  -1.213  -1.184  -1.025
56    I         0.192   0.179   0.273   0.065   0.026   0.163  -0.160  -0.204  -0.068
57    L        -1.215  -1.219  -1.173  -1.325  -1.278  -1.156  -1.108  -1.096  -1.005
58    K        -0.519  -0.489  -0.383  -0.668  -0.624  -0.468  -0.792  -0.744  -0.603
59    E         1.311   1.342   1.401   1.264   1.320   1.410   1.419   1.463   1.556
60    V        -0.519  -0.431  -0.361  -0.634  -0.485  -0.398  -0.792  -0.666  -0.575
61    S        -1.508  -1.259  -1.447  -1.298  -0.940  -1.242  -1.213  -0.960  -1.097
62    N        -1.215  -1.173  -1.168  -1.225  -1.168  -1.144  -1.108  -1.058  -1.001
63    L         0.674   0.541   0.444   0.454   0.284   0.158   0.682   0.463   0.261
64    R        -0.922  -0.767  -0.803  -1.034  -0.799  -0.848  -1.002  -0.811  -0.825
65    K        -0.211  -0.285  -0.312  -0.166  -0.283  -0.336  -0.371  -0.472  -0.511
66    N        -0.812  -0.892  -0.804  -0.914  -1.021  -0.899  -0.897  -0.951  -0.828
67    T        -1.215  -1.237  -1.179  -1.064  -1.124  -1.027  -1.108  -1.112  -1.010
68    E        -1.033  -1.135  -1.165  -1.004  -1.213  -1.283  -0.897  -0.999  -0.994
69    Y        -1.033  -1.112  -1.158  -0.724  -0.864  -0.938  -0.897  -0.978  -0.988
70    L         0.067  -0.121  -0.246  -0.098  -0.347  -0.514   0.051  -0.216  -0.409
71    K        -1.619  -1.513  -1.490  -1.710  -1.623  -1.505  -1.318  -1.210  -1.133
72    E        -0.504  -0.594  -0.743  -0.420  -0.564  -0.813  -0.476  -0.594  -0.754
73    Q        -0.473  -0.394  -0.358  -0.714  -0.562  -0.528  -0.737  -0.627  -0.570
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    Q        -0.336  -0.279  -0.298  -0.494  -0.377  -0.388  -0.581  -0.481  -0.495
80    Q        -1.912  -1.878  -1.758  -1.809  -1.721  -1.607  -1.424  -1.374  -1.223
81    L        -1.326  -1.263  -1.183  -1.498  -1.373  -1.231  -1.213  -1.137  -1.014
82    G        -1.619  -1.592  -1.495  -1.474  -1.452  -1.287  -1.318  -1.274  -1.136
83    M        -1.912  -1.818  -1.745  -1.564  -1.456  -1.322  -1.424  -1.333  -1.214
84    L        -1.326  -1.266  -1.194  -1.388  -1.220  -1.140  -1.213  -1.134  -1.022
85    D         0.360   0.268   0.298   0.230   0.061   0.082   0.156  -0.029  -0.017
86    D        -1.326  -1.231  -1.191  -1.328  -1.157  -1.128  -1.213  -1.110  -1.021
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    K        -0.504  -0.680  -0.768  -0.270  -0.513  -0.673  -0.476  -0.689  -0.783
91    V        -0.812  -0.865  -0.802  -0.785  -0.851  -0.755  -0.897  -0.927  -0.827
92    A        -1.215  -1.203  -1.175  -1.089  -1.097  -1.047  -1.108  -1.078  -1.004
93    K        -0.922  -0.908  -0.828  -0.921  -0.879  -0.749  -1.002  -0.968  -0.854
94    C         0.674   0.541   0.444   1.007   0.831   0.661   0.682   0.463   0.261
95    Q        -0.504  -0.680  -0.768  -0.327  -0.578  -0.721  -0.476  -0.689  -0.783
96    Y         0.192   0.305   0.318  -0.239  -0.068  -0.033  -0.160   0.040   0.021
97    F        -0.336  -0.276  -0.325  -0.520  -0.517  -0.540  -0.581  -0.514  -0.532
98    V         0.674   0.541   0.444   0.836   0.676   0.533   0.682   0.463   0.261
99    T        -1.033  -1.135  -1.165  -0.746  -0.909  -0.970  -0.897  -0.999  -0.994
100   L        -0.211  -0.032  -0.256  -0.083   0.221  -0.172  -0.371  -0.104  -0.426
101   L         0.674   0.541   0.444   0.441   0.268   0.127   0.682   0.463   0.261
102   C        -0.336  -0.312  -0.300  -0.305  -0.262  -0.234  -0.581  -0.515  -0.496
103   M         0.674   0.541   0.444   0.968   0.790   0.609   0.682   0.463   0.261
104   E        -0.336  -0.368  -0.317  -0.468  -0.474  -0.410  -0.581  -0.585  -0.518
105   R         0.674   0.541   0.444   0.810   0.628   0.484   0.682   0.463   0.261
106   N         0.674   0.622   0.452   0.788   0.732   0.446   0.682   0.597   0.277
107   K         1.311   1.342   1.401   1.364   1.420   1.506   1.419   1.463   1.556
108   R         1.311   1.342   1.401   1.364   1.399   1.506   1.419   1.463   1.556
109   C         1.311   1.342   1.401   1.563   1.610   1.696   1.419   1.463   1.556
110   L         1.311   1.342   1.401   1.009   1.057   1.167   1.419   1.463   1.556
111   L         0.674   0.541   0.444   0.473   0.318   0.205   0.682   0.463   0.261
112   A         1.311   1.342   1.401   1.412   1.445   1.551   1.419   1.463   1.556
113   Y         1.311   1.342   1.401   1.418   1.463   1.557   1.419   1.463   1.556
114   Q        -0.447  -0.437  -0.365  -0.539  -0.502  -0.410  -0.686  -0.675  -0.579
115   R        -0.740  -0.842  -0.799  -0.641  -0.771  -0.724  -0.792  -0.885  -0.822
116   L        -1.033  -1.005  -1.116  -1.104  -1.069  -1.171  -0.897  -0.858  -0.948
117   R         1.311   1.342   1.401   1.364   1.399   1.506   1.419   1.463   1.556
118   T        -0.812  -0.823  -0.798  -0.837  -0.907  -0.857  -0.897  -0.890  -0.823
119   D        -0.504  -0.621  -0.751  -0.423  -0.603  -0.826  -0.476  -0.623  -0.763
120   I        -0.922  -0.840  -0.820  -0.903  -0.800  -0.736  -1.002  -0.909  -0.846
121   L        -0.211  -0.203  -0.282  -0.471  -0.433  -0.512  -0.371  -0.341  -0.463
122   D        -1.033  -1.146  -1.159  -0.922  -1.103  -1.132  -0.897  -1.009  -0.988
123   S        -0.740  -0.694  -0.772  -0.787  -0.707  -0.835  -0.792  -0.723  -0.790
124   M        -1.619  -1.615  -1.503  -1.354  -1.375  -1.246  -1.318  -1.289  -1.142
125   A        -0.922  -0.871  -0.825  -0.823  -0.755  -0.679  -1.002  -0.942  -0.851
126   W         1.311   1.342   1.401   1.603   1.648   1.734   1.419   1.463   1.556
127   N        -1.309  -1.270  -1.197  -1.481  -1.434  -1.263  -1.194  -1.142  -1.024
128   N         0.299   0.228   0.288   0.257   0.122   0.202   0.044  -0.108  -0.037
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   N        -0.387  -0.450  -0.345  -0.563  -0.634  -0.484  -0.643  -0.697  -0.556
131   G        -0.848  -0.917  -0.826  -0.698  -0.815  -0.680  -0.919  -0.974  -0.850
132   L        -0.975  -0.887  -0.832  -1.122  -0.965  -0.892  -1.056  -0.956  -0.857
133   D        -0.473  -0.402  -0.363  -0.720  -0.622  -0.543  -0.737  -0.644  -0.578
134   L        -0.941  -0.881  -0.830  -1.175  -1.095  -0.969  -1.007  -0.928  -0.853
135   M        -0.941  -0.869  -0.830  -0.936  -0.832  -0.775  -1.007  -0.916  -0.853
136   S        -0.941  -0.937  -0.843  -1.110  -1.098  -0.992  -1.007  -0.992  -0.866
137   S        -0.941  -0.893  -0.831  -0.976  -0.920  -0.819  -1.007  -0.942  -0.853
138   I        -0.473  -0.470  -0.368  -0.608  -0.605  -0.446  -0.737  -0.722  -0.584
139   T        -0.473  -0.402  -0.363  -0.584  -0.494  -0.418  -0.737  -0.644  -0.578
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   F        -1.328  -1.278  -1.211  -1.383  -1.333  -1.263  -1.201  -1.138  -1.036
171   S        -1.619  -1.615  -1.503  -1.485  -1.494  -1.330  -1.318  -1.289  -1.142
172   Q        -0.812  -0.731  -0.770  -0.881  -0.763  -0.803  -0.897  -0.803  -0.796
173   Q        -1.912  -1.855  -1.761  -1.849  -1.707  -1.562  -1.424  -1.361  -1.225
174   D        -1.215  -1.241  -1.172  -1.347  -1.435  -1.308  -1.108  -1.114  -1.004
175   T        -1.508  -1.514  -1.476  -1.373  -1.426  -1.410  -1.213  -1.205  -1.121
176   N        -1.215  -1.263  -1.174  -1.107  -1.163  -1.045  -1.108  -1.132  -1.005
177   N        -0.336  -0.275  -0.317  -0.429  -0.353  -0.385  -0.581  -0.511  -0.523
178   L         1.311   1.342   1.401   1.009   1.057   1.167   1.419   1.463   1.556
179   S         0.192   0.226   0.289   0.015   0.070   0.151  -0.160  -0.111  -0.036
180   H        -0.504  -0.680  -0.768  -0.055  -0.324  -0.474  -0.476  -0.689  -0.783
181   Q        -1.326  -1.289  -1.187  -1.198  -1.148  -0.985  -1.213  -1.156  -1.018
182   E         1.311   1.342   1.401   1.264   1.320   1.410   1.419   1.463   1.556
183   Q         0.067  -0.069  -0.238   0.179  -0.008  -0.298   0.051  -0.145  -0.397
184   E         0.192   0.192   0.275  -0.099  -0.112   0.006  -0.160  -0.178  -0.064
185   Y         0.674   0.743   0.474   0.873   0.964   0.603   0.682   0.785   0.316
186   L        -0.740  -0.721  -0.780  -0.878  -0.838  -0.841  -0.792  -0.759  -0.803
187   K         0.067  -0.069  -0.238   0.255   0.073  -0.202   0.051  -0.145  -0.397
188   E        -1.215  -1.265  -1.179  -1.213  -1.278  -1.142  -1.108  -1.134  -1.010
189   Y         0.674   0.683   0.464   0.873   0.892   0.589   0.682   0.693   0.299
190   C        -1.619  -1.588  -1.494  -1.433  -1.426  -1.248  -1.318  -1.272  -1.135
191   D        -0.740  -0.662  -0.764  -0.774  -0.684  -0.797  -0.792  -0.709  -0.786
192   L         1.311   1.342   1.401   1.009   1.057   1.167   1.419   1.463   1.556
193   I         0.192   0.194   0.275  -0.124  -0.160  -0.070  -0.160  -0.173  -0.064
194   T        -0.740  -0.785  -0.798  -0.575  -0.675  -0.653  -0.792  -0.846  -0.822
195   D        -1.215  -1.239  -1.171  -1.342  -1.380  -1.300  -1.108  -1.112  -1.002
196   L        -0.812  -0.780  -0.782  -0.986  -0.875  -0.848  -0.897  -0.839  -0.805
197   K         1.311   1.342   1.401   1.364   1.420   1.506   1.419   1.463   1.556
198   S         0.192   0.179   0.273   0.044   0.007   0.158  -0.160  -0.204  -0.068
199   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   D        -1.912  -1.869  -1.750  -1.727  -1.645  -1.512  -1.424  -1.369  -1.218
201   L        -1.326  -1.254  -1.198  -1.203  -1.046  -0.982  -1.213  -1.127  -1.026
202   V        -1.326  -1.215  -1.187  -1.281  -1.145  -1.088  -1.213  -1.101  -1.018
203   D         0.360   0.325   0.310   0.215   0.149   0.080   0.156   0.078   0.006
204   I         0.674   0.541   0.444   0.772   0.580   0.363   0.682   0.463   0.261
205   D         1.311   1.342   1.401   1.261   1.312   1.407   1.419   1.463   1.556
206   L         1.311   1.342   1.401   1.009   1.057   1.167   1.419   1.463   1.556
207   S         0.139   0.196   0.287  -0.061   0.040   0.182  -0.265  -0.170  -0.040
208   G         1.311   1.342   1.401   1.418   1.460   1.557   1.419   1.463   1.556
209   S        -0.211  -0.087  -0.261  -0.212  -0.025  -0.271  -0.371  -0.193  -0.433
210   L         1.311   1.342   1.401   1.009   1.057   1.167   1.419   1.463   1.556
211   V        -1.215  -1.111  -1.151  -1.235  -1.082  -1.146  -1.108  -1.000  -0.986
212   P         1.311   1.342   1.401   1.517   1.555   1.652   1.419   1.463   1.556
213   P         1.311   1.342   1.401   1.517   1.555   1.652   1.419   1.463   1.556
214   S        -1.215  -1.290  -1.190  -1.121  -1.226  -1.085  -1.108  -1.151  -1.019
215   D         0.192   0.204   0.280  -0.046  -0.029   0.081  -0.160  -0.154  -0.054
216   V        -0.447  -0.437  -0.365  -0.670  -0.711  -0.619  -0.686  -0.675  -0.579
217   F         1.311   1.342   1.401   1.485   1.536   1.621   1.419   1.463   1.556
218   I         0.674   0.756   0.473   0.825   0.943   0.542   0.682   0.804   0.314
219   D         1.311   1.342   1.401   1.261   1.312   1.407   1.419   1.463   1.556
220   V         1.311   1.342   1.401   1.373   1.421   1.514   1.419   1.463   1.556
221   R         1.311   1.342   1.401   1.364   1.399   1.506   1.419   1.463   1.556
222   V         1.311   1.342   1.401   1.373   1.421   1.514   1.419   1.463   1.556
223   L         1.311   1.342   1.401   1.009   1.057   1.167   1.419   1.463   1.556
224   K         0.674   0.622   0.452   0.795   0.742   0.462   0.682   0.597   0.277
225   D         0.067   0.070  -0.206   0.141   0.148  -0.263   0.051   0.051  -0.350
226   A        -0.447  -0.448  -0.365  -0.469  -0.507  -0.376  -0.686  -0.692  -0.580
227   G         1.311   1.342   1.401   1.418   1.460   1.557   1.419   1.463   1.556
228   E         0.067  -0.000  -0.223   0.123   0.026  -0.333   0.051  -0.056  -0.375
229   I         0.192   0.226   0.289   0.065   0.123   0.196  -0.160  -0.111  -0.036
230   Q        -0.211  -0.202  -0.297  -0.257  -0.265  -0.412  -0.371  -0.376  -0.491
231   T         1.311   1.342   1.401   1.400   1.442   1.540   1.419   1.463   1.556
232   E         1.311   1.342   1.401   1.264   1.320   1.410   1.419   1.463   1.556
233   Y         1.311   1.342   1.401   1.418   1.463   1.557   1.419   1.463   1.556
234   G         1.311   1.342   1.401   1.418   1.460   1.557   1.419   1.463   1.556
235   V        -0.504  -0.588  -0.738  -0.272  -0.402  -0.637  -0.476  -0.582  -0.748
236   F         0.360   0.293   0.312   0.470   0.347   0.332   0.156   0.017   0.010
237   N         1.311   1.342   1.401   1.364   1.419   1.506   1.419   1.463   1.556
238   L         1.311   1.342   1.401   1.009   1.057   1.167   1.419   1.463   1.556
239   I        -0.211  -0.319  -0.326  -0.163  -0.339  -0.378  -0.371  -0.526  -0.530
240   K         1.311   1.342   1.401   1.364   1.420   1.506   1.419   1.463   1.556
241   D         0.360   0.293   0.312   0.248   0.131   0.139   0.156   0.017   0.010
242   S         1.311   1.342   1.401   1.331   1.379   1.474   1.419   1.463   1.556
243   Q         1.311   1.342   1.401   1.310   1.364   1.454   1.419   1.463   1.556
244   F         0.674   0.541   0.444   0.876   0.678   0.460   0.682   0.463   0.261
245   F        -0.211  -0.296  -0.307  -0.006  -0.106  -0.157  -0.371  -0.472  -0.504
246   V         1.311   1.342   1.401   1.373   1.421   1.514   1.419   1.463   1.556
247   R         1.311   1.342   1.401   1.364   1.399   1.506   1.419   1.463   1.556
248   Q        -0.740  -0.837  -0.791  -0.706  -0.833  -0.774  -0.792  -0.879  -0.811
249   S         0.067  -0.069  -0.238   0.232   0.045  -0.211   0.051  -0.145  -0.397
250   D         1.311   1.342   1.401   1.261   1.312   1.407   1.419   1.463   1.556
251   V         1.311   1.342   1.401   1.373   1.421   1.514   1.419   1.463   1.556
252   E         0.674   0.622   0.452   0.695   0.643   0.370   0.682   0.597   0.277
253   R         0.674   0.622   0.452   0.808   0.735   0.492   0.682   0.597   0.277
254   L         1.311   1.342   1.401   1.009   1.057   1.167   1.419   1.463   1.556
255   I         0.674   0.622   0.452   0.772   0.708   0.381   0.682   0.597   0.277
256   Q        -0.504  -0.680  -0.768  -0.401  -0.679  -0.870  -0.476  -0.689  -0.783
257   Q         1.311   1.342   1.401   1.310   1.364   1.454   1.419   1.463   1.556
258   G         1.311   1.342   1.401   1.418   1.460   1.557   1.419   1.463   1.556
259   Y         0.674   0.541   0.444   0.873   0.707   0.556   0.682   0.463   0.261
260   L         1.311   1.342   1.401   1.009   1.057   1.167   1.419   1.463   1.556
261   Q        -0.740  -0.837  -0.791  -0.752  -0.871  -0.823  -0.792  -0.879  -0.811
262   K         0.192   0.226   0.289  -0.008   0.053   0.118  -0.160  -0.111  -0.036
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   I         0.067  -0.069  -0.238   0.220   0.006  -0.305   0.051  -0.145  -0.397
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12488
Output conservation file - output/Q12488
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
