1     M         1.292   1.299   1.372   1.593   1.601   1.696   1.400   1.409   1.515
2     F        -0.266  -0.239  -0.345  -0.345  -0.308  -0.474  -0.419  -0.388  -0.525
3     K        -0.881  -0.882  -0.843  -0.921  -0.910  -0.876  -0.954  -0.950  -0.852
4     S        -1.262  -1.255  -1.241  -1.297  -1.282  -1.294  -1.116  -1.108  -1.048
5     L        -1.014  -0.979  -0.887  -0.991  -0.943  -0.825  -1.066  -1.024  -0.891
6     A        -1.014  -1.016  -0.890  -1.239  -1.246  -1.015  -1.066  -1.066  -0.895
7     A        -1.108  -1.057  -1.191  -0.720  -0.657  -0.898  -0.954  -0.898  -1.000
8     V        -1.708  -1.713  -1.563  -1.728  -1.736  -1.520  -1.383  -1.381  -1.179
9     L        -1.595  -1.558  -1.534  -1.360  -1.299  -1.376  -1.276  -1.239  -1.156
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    P        -2.308  -2.292  -2.066  -2.182  -2.162  -1.840  -1.597  -1.581  -1.334
25    R         1.292   1.299   1.372   1.478   1.486   1.589   1.400   1.409   1.515
26    A        -1.295  -1.217  -1.224  -1.488  -1.379  -1.349  -1.168  -1.090  -1.035
27    S        -0.808  -0.830  -0.841  -0.649  -0.708  -0.753  -0.847  -0.877  -0.847
28    K        -1.295  -1.278  -1.235  -1.323  -1.294  -1.263  -1.168  -1.149  -1.044
29    A        -0.995  -0.968  -0.882  -1.187  -1.157  -0.989  -1.061  -1.033  -0.890
30    K        -1.734  -1.748  -1.579  -1.698  -1.731  -1.521  -1.396  -1.403  -1.190
31    F        -0.919  -0.931  -0.869  -0.641  -0.668  -0.573  -0.976  -0.993  -0.877
32    L        -1.391  -1.371  -1.259  -1.222  -1.190  -1.008  -1.256  -1.234  -1.065
33    Q        -1.391  -1.411  -1.259  -1.293  -1.309  -1.097  -1.256  -1.268  -1.066
34    K        -0.705  -0.797  -0.836  -0.631  -0.768  -0.815  -0.697  -0.807  -0.835
35    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    S         0.319   0.369   0.310   0.192   0.266   0.171   0.116   0.203   0.050
44    T         0.019  -0.032  -0.272   0.194   0.120  -0.315   0.009  -0.064  -0.413
45    L         1.292   1.299   1.372   1.189   1.198   1.318   1.400   1.409   1.515
46    A         0.319   0.271   0.271   0.040  -0.030  -0.021   0.116   0.027  -0.026
47    F        -0.395  -0.375  -0.374  -0.437  -0.421  -0.426  -0.633  -0.613  -0.571
48    I        -0.581  -0.561  -0.434  -0.898  -0.872  -0.669  -0.847  -0.820  -0.642
49    E         1.292   1.299   1.372   1.360   1.370   1.478   1.400   1.409   1.515
50    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    S        -1.295  -1.312  -1.239  -1.108  -1.117  -0.987  -1.168  -1.179  -1.048
52    K        -2.008  -1.988  -1.831  -1.834  -1.789  -1.597  -1.490  -1.471  -1.266
53    D        -1.408  -1.380  -1.256  -1.299  -1.267  -1.086  -1.276  -1.250  -1.064
54    G         0.019   0.095  -0.259   0.159   0.257  -0.242   0.009   0.114  -0.394
55    S        -2.008  -2.016  -1.828  -1.872  -1.870  -1.632  -1.490  -1.490  -1.264
56    V        -0.266  -0.317  -0.354  -0.327  -0.421  -0.504  -0.419  -0.492  -0.535
57    S        -0.566  -0.503  -0.767  -0.531  -0.443  -0.864  -0.526  -0.447  -0.755
58    R         0.019   0.012  -0.266   0.300   0.292  -0.111   0.009  -0.001  -0.403
59    S        -0.266  -0.245  -0.347  -0.568  -0.537  -0.682  -0.419  -0.395  -0.528
60    S         0.640   0.666   0.416   0.638   0.669   0.346   0.651   0.690   0.247
61    L         1.292   1.299   1.372   1.189   1.198   1.318   1.400   1.409   1.515
62    S         0.319   0.349   0.290   0.220   0.262   0.177   0.116   0.168   0.011
63    L        -0.266  -0.262  -0.341  -0.507  -0.492  -0.600  -0.419  -0.402  -0.518
64    L        -0.395  -0.368  -0.372  -0.664  -0.636  -0.596  -0.633  -0.605  -0.568
65    A        -1.595  -1.623  -1.545  -1.303  -1.359  -1.274  -1.276  -1.299  -1.164
66    A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
67    A         0.640   0.637   0.413   0.450   0.453   0.131   0.651   0.646   0.242
68    Q        -1.408  -1.393  -1.262  -1.273  -1.253  -1.077  -1.276  -1.258  -1.068
69    K        -1.295  -1.296  -1.234  -1.008  -1.003  -0.899  -1.168  -1.162  -1.043
70    L        -0.266  -0.297  -0.342  -0.355  -0.383  -0.449  -0.419  -0.445  -0.516
71    S         0.019  -0.015  -0.273   0.133   0.090  -0.317   0.009  -0.037  -0.414
72    N        -0.881  -0.831  -0.857  -0.799  -0.738  -0.749  -0.954  -0.905  -0.866
73    P        -0.266  -0.275  -0.347  -0.098  -0.127  -0.214  -0.419  -0.442  -0.527
74    I         0.147   0.143   0.235  -0.095  -0.114   0.019  -0.205  -0.216  -0.095
75    T        -0.566  -0.592  -0.783  -0.193  -0.232  -0.472  -0.526  -0.560  -0.775
76    A         0.640   0.558   0.405   0.463   0.364   0.147   0.651   0.522   0.227
77    V        -0.995  -0.968  -0.891  -1.106  -1.064  -0.930  -1.061  -1.034  -0.899
78    I        -0.581  -0.560  -0.432  -0.896  -0.866  -0.665  -0.847  -0.819  -0.640
79    T        -1.595  -1.627  -1.547  -1.652  -1.703  -1.549  -1.276  -1.302  -1.166
80    G         0.640   0.673   0.419   0.696   0.741   0.366   0.651   0.701   0.252
81    S         0.019  -0.018  -0.267   0.079   0.026  -0.316   0.009  -0.046  -0.406
82    K        -0.995  -0.990  -0.883  -0.948  -0.942  -0.779  -1.061  -1.052  -0.891
83    A        -0.808  -0.816  -0.837  -1.084  -1.090  -1.122  -0.847  -0.848  -0.839
84    E        -2.008  -2.009  -1.826  -1.823  -1.838  -1.578  -1.490  -1.486  -1.264
85    K        -1.708  -1.725  -1.561  -1.752  -1.743  -1.481  -1.383  -1.390  -1.177
86    T        -0.995  -1.013  -0.888  -1.271  -1.297  -1.080  -1.061  -1.076  -0.897
87    A         0.640   0.558   0.405   0.450   0.347   0.117   0.651   0.522   0.227
88    E        -0.808  -0.818  -0.832  -0.811  -0.803  -0.867  -0.847  -0.854  -0.836
89    A        -1.595  -1.591  -1.539  -1.523  -1.520  -1.381  -1.276  -1.270  -1.160
90    L        -0.395  -0.372  -0.374  -0.718  -0.690  -0.692  -0.633  -0.609  -0.568
91    K        -0.266  -0.262  -0.350  -0.472  -0.468  -0.534  -0.419  -0.421  -0.529
92    S         0.019  -0.015  -0.273   0.188   0.148  -0.238   0.009  -0.037  -0.414
93    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    C        -0.995  -0.963  -0.882  -0.961  -0.920  -0.773  -1.061  -1.028  -0.890
97    S        -1.708  -1.709  -1.564  -1.528  -1.527  -1.298  -1.383  -1.379  -1.180
98    N        -0.808  -0.864  -0.835  -0.784  -0.847  -0.804  -0.847  -0.899  -0.839
99    L        -0.508  -0.455  -0.414  -0.780  -0.691  -0.644  -0.740  -0.664  -0.614
100   E        -1.295  -1.314  -1.237  -1.317  -1.342  -1.226  -1.168  -1.183  -1.047
101   K         0.019   0.035  -0.261   0.163   0.192  -0.270   0.009   0.031  -0.397
102   L        -0.395  -0.404  -0.372  -0.615  -0.628  -0.563  -0.633  -0.635  -0.567
103   V        -0.508  -0.521  -0.421  -0.780  -0.809  -0.657  -0.740  -0.759  -0.623
104   I        -0.566  -0.643  -0.791  -0.412  -0.513  -0.696  -0.526  -0.621  -0.784
105   F        -1.295  -1.276  -1.231  -1.488  -1.440  -1.379  -1.168  -1.144  -1.041
106   E        -1.295  -1.251  -1.228  -1.136  -1.061  -1.034  -1.168  -1.118  -1.037
107   D        -0.995  -0.975  -0.884  -0.967  -0.936  -0.801  -1.061  -1.040  -0.892
108   S        -0.808  -0.792  -0.840  -0.811  -0.797  -0.835  -0.847  -0.837  -0.845
109   K        -1.408  -1.389  -1.259  -1.568  -1.533  -1.294  -1.276  -1.256  -1.067
110   L        -0.266  -0.274  -0.350  -0.026  -0.040  -0.189  -0.419  -0.429  -0.529
111   D         0.640   0.558   0.405   0.816   0.710   0.483   0.651   0.522   0.227
112   T        -0.566  -0.548  -0.775  -0.071  -0.048  -0.426  -0.526  -0.503  -0.765
113   C        -1.295  -1.332  -1.241  -0.939  -0.977  -0.871  -1.168  -1.196  -1.049
114   L         0.640   0.558   0.405   0.620   0.514   0.293   0.651   0.522   0.227
115   P         0.319   0.369   0.310   0.289   0.379   0.204   0.116   0.203   0.050
116   E         0.640   0.558   0.405   0.802   0.700   0.474   0.651   0.522   0.227
117   Q        -1.408  -1.372  -1.258  -1.128  -1.075  -0.908  -1.276  -1.243  -1.065
118   L        -1.108  -1.096  -0.919  -1.206  -1.197  -0.933  -1.168  -1.153  -0.925
119   T        -0.508  -0.478  -0.406  -0.880  -0.826  -0.704  -0.740  -0.697  -0.603
120   P         0.019  -0.038  -0.272   0.312   0.237  -0.096   0.009  -0.073  -0.412
121   L        -0.266  -0.299  -0.354  -0.462  -0.526  -0.651  -0.419  -0.471  -0.538
122   L        -0.266  -0.205  -0.335  -0.411  -0.321  -0.522  -0.419  -0.335  -0.510
123   V        -1.408  -1.420  -1.261  -1.492  -1.494  -1.221  -1.276  -1.279  -1.067
124   K        -0.808  -0.772  -0.829  -0.754  -0.699  -0.823  -0.847  -0.807  -0.833
125   L        -1.295  -1.246  -1.242  -1.343  -1.270  -1.289  -1.168  -1.126  -1.051
126   L        -0.808  -0.827  -0.843  -0.880  -0.912  -0.923  -0.847  -0.861  -0.848
127   K        -0.266  -0.205  -0.328  -0.193  -0.096  -0.260  -0.419  -0.328  -0.497
128   G        -1.295  -1.269  -1.229  -1.255  -1.212  -1.153  -1.168  -1.140  -1.040
129   G        -1.108  -1.116  -1.198  -0.853  -0.863  -0.977  -0.954  -0.964  -1.007
130   D        -0.808  -0.822  -0.843  -0.696  -0.711  -0.760  -0.847  -0.857  -0.846
131   Y        -0.266  -0.307  -0.347   0.046  -0.008  -0.110  -0.419  -0.462  -0.526
132   S         0.092   0.103   0.228  -0.165  -0.159   0.047  -0.312  -0.294  -0.109
133   H         1.292   1.299   1.372   1.588   1.595   1.692   1.400   1.409   1.515
134   F        -0.266  -0.271  -0.355  -0.122  -0.153  -0.318  -0.419  -0.437  -0.538
135   V        -0.808  -0.811  -0.838  -0.872  -0.863  -0.889  -0.847  -0.844  -0.842
136   V        -1.408  -1.413  -1.265  -1.632  -1.645  -1.397  -1.276  -1.274  -1.071
137   S        -0.581  -0.574  -0.437  -0.929  -0.931  -0.711  -0.847  -0.836  -0.646
138   N        -1.295  -1.332  -1.233  -1.396  -1.414  -1.221  -1.168  -1.199  -1.044
139   S         0.640   0.673   0.419   0.638   0.677   0.350   0.651   0.701   0.252
140   S        -0.395  -0.436  -0.377  -0.746  -0.777  -0.668  -0.633  -0.668  -0.572
141   V        -0.266  -0.209  -0.333  -0.285  -0.211  -0.365  -0.419  -0.339  -0.505
142   G         1.292   1.299   1.372   1.280   1.291   1.403   1.400   1.409   1.515
143   K         1.292   1.299   1.372   1.310   1.324   1.431   1.400   1.409   1.515
144   S        -0.581  -0.588  -0.440  -0.743  -0.758  -0.531  -0.847  -0.853  -0.650
145   V        -0.808  -0.757  -0.822  -0.846  -0.780  -0.849  -0.847  -0.787  -0.825
146   L         0.319   0.289   0.285   0.260   0.218   0.233   0.116   0.059   0.002
147   P         0.640   0.637   0.413   0.834   0.830   0.496   0.651   0.646   0.242
148   R         1.292   1.299   1.372   1.478   1.486   1.589   1.400   1.409   1.515
149   V        -0.266  -0.295  -0.353  -0.404  -0.460  -0.552  -0.419  -0.463  -0.537
150   G        -0.266  -0.274  -0.353  -0.404  -0.433  -0.600  -0.419  -0.440  -0.535
151   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
152   L         0.019  -0.064  -0.275   0.120   0.022  -0.239   0.009  -0.107  -0.417
153   L         0.019  -0.018  -0.267   0.142   0.093  -0.184   0.009  -0.046  -0.406
154   D         1.292   1.299   1.372   1.377   1.383   1.494   1.400   1.409   1.515
155   V        -1.295  -1.235  -1.217  -1.502  -1.407  -1.410  -1.168  -1.109  -1.029
156   Q         0.019  -0.038  -0.272   0.434   0.365   0.034   0.009  -0.073  -0.412
157   P         0.147   0.141   0.238   0.160   0.148   0.288  -0.205  -0.219  -0.089
158   V         0.092   0.099   0.226  -0.225  -0.219  -0.006  -0.312  -0.302  -0.113
159   C         0.319   0.318   0.294   0.272   0.269   0.259   0.116   0.112   0.020
160   E         0.319   0.324   0.282   0.362   0.367   0.266   0.116   0.123  -0.003
161   V         0.092   0.099   0.226  -0.225  -0.220  -0.006  -0.312  -0.302  -0.113
162   T        -0.808  -0.828  -0.839  -0.769  -0.798  -0.859  -0.847  -0.865  -0.843
163   V        -1.108  -1.173  -1.208  -0.986  -1.085  -1.221  -0.954  -1.023  -1.016
164   I         0.092   0.099   0.226  -0.225  -0.220  -0.006  -0.312  -0.302  -0.113
165   K        -0.995  -0.994  -0.889  -1.099  -1.111  -0.963  -1.061  -1.063  -0.898
166   D         0.092   0.099   0.226  -0.170  -0.164   0.044  -0.312  -0.302  -0.113
167   P        -0.395  -0.446  -0.373  -0.444  -0.522  -0.430  -0.633  -0.686  -0.568
168   K        -1.295  -1.305  -1.234  -0.986  -1.014  -0.903  -1.168  -1.178  -1.044
169   T         1.292   1.299   1.372   1.384   1.391   1.500   1.400   1.409   1.515
170   F         1.292   1.299   1.372   1.489   1.496   1.599   1.400   1.409   1.515
171   I         0.640   0.612   0.410   0.631   0.594   0.312   0.651   0.608   0.236
172   R         1.292   1.299   1.372   1.478   1.486   1.589   1.400   1.409   1.515
173   P         1.292   1.299   1.372   1.405   1.413   1.521   1.400   1.409   1.515
174   I         0.019  -0.036  -0.267   0.231   0.153  -0.129   0.009  -0.070  -0.406
175   Y         1.292   1.299   1.372   1.559   1.567   1.664   1.400   1.409   1.515
176   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
177   G         1.292   1.299   1.372   1.280   1.291   1.403   1.400   1.409   1.515
178   N         1.292   1.299   1.372   1.459   1.465   1.571   1.400   1.409   1.515
179   I        -0.395  -0.451  -0.384  -0.752  -0.824  -0.697  -0.633  -0.694  -0.581
180   I        -0.395  -0.434  -0.372  -0.543  -0.577  -0.460  -0.633  -0.666  -0.566
181   S        -1.108  -1.178  -1.206  -1.199  -1.311  -1.337  -0.954  -1.028  -1.015
182   T         1.292   1.299   1.372   1.384   1.391   1.500   1.400   1.409   1.515
183   I         0.319   0.301   0.289   0.171   0.137   0.102   0.116   0.082   0.010
184   E        -0.395  -0.447  -0.376  -0.483  -0.551  -0.448  -0.633  -0.687  -0.572
185   C         0.019  -0.086  -0.278   0.133   0.000  -0.224   0.009  -0.138  -0.422
186   Q        -1.295  -1.256  -1.229  -1.076  -1.028  -0.979  -1.168  -1.131  -1.039
187   A        -0.808  -0.791  -0.836  -0.653  -0.637  -0.727  -0.847  -0.826  -0.839
188   E        -0.995  -0.987  -0.887  -1.022  -0.995  -0.867  -1.061  -1.045  -0.896
189   K        -0.266  -0.262  -0.350  -0.222  -0.229  -0.328  -0.419  -0.421  -0.529
190   K        -0.566  -0.505  -0.775  -0.352  -0.261  -0.668  -0.526  -0.450  -0.765
191   L         0.319   0.289   0.285   0.160   0.107   0.085   0.116   0.059   0.002
192   L        -1.108  -1.095  -0.918  -1.522  -1.498  -1.208  -1.168  -1.152  -0.924
193   I        -0.395  -0.418  -0.379  -0.541  -0.572  -0.483  -0.633  -0.659  -0.576
194   I         0.147   0.148   0.242  -0.130  -0.136   0.017  -0.205  -0.207  -0.081
195   R         1.292   1.299   1.372   1.478   1.486   1.589   1.400   1.409   1.515
196   A        -0.566  -0.527  -0.767  -0.654  -0.593  -0.934  -0.526  -0.477  -0.755
197   S         0.640   0.673   0.419   0.638   0.677   0.350   0.651   0.701   0.252
198   A         0.640   0.637   0.413   0.450   0.453   0.131   0.651   0.646   0.242
199   F         1.292   1.299   1.372   1.489   1.496   1.599   1.400   1.409   1.515
200   P        -0.266  -0.283  -0.354  -0.183  -0.223  -0.377  -0.419  -0.456  -0.537
201   P         0.092   0.100   0.226  -0.262  -0.257  -0.046  -0.312  -0.300  -0.112
202   I        -0.395  -0.416  -0.373  -0.760  -0.796  -0.697  -0.633  -0.657  -0.569
203   A        -0.881  -0.909  -0.854  -1.043  -1.076  -0.961  -0.954  -0.976  -0.862
204   E        -1.708  -1.678  -1.558  -1.896  -1.843  -1.678  -1.383  -1.355  -1.176
205   G        -0.266  -0.268  -0.350  -0.312  -0.327  -0.457  -0.419  -0.430  -0.532
206   S         0.092   0.099   0.226  -0.243  -0.233  -0.023  -0.312  -0.302  -0.113
207   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   D        -1.108  -1.092  -1.199  -0.967  -0.941  -1.151  -0.954  -0.936  -1.008
209   S        -0.566  -0.612  -0.788  -0.528  -0.611  -0.896  -0.526  -0.584  -0.780
210   V         0.019   0.032  -0.260  -0.100  -0.082  -0.484   0.009   0.026  -0.396
211   T        -1.408  -1.390  -1.258  -1.441  -1.400  -1.208  -1.276  -1.255  -1.065
212   I         0.092   0.099   0.226  -0.225  -0.221  -0.008  -0.312  -0.302  -0.112
213   E        -0.566  -0.623  -0.788  -0.346  -0.435  -0.727  -0.526  -0.597  -0.780
214   K        -1.295  -1.264  -1.224  -1.063  -1.023  -0.949  -1.168  -1.134  -1.034
215   R        -1.014  -1.015  -0.895  -0.965  -0.965  -0.770  -1.066  -1.064  -0.900
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   T        -0.808  -0.816  -0.843  -0.787  -0.812  -0.914  -0.847  -0.862  -0.847
221   D        -1.595  -1.601  -1.540  -1.399  -1.422  -1.304  -1.276  -1.279  -1.160
222   I        -0.808  -0.782  -0.831  -0.714  -0.667  -0.746  -0.847  -0.807  -0.832
223   P        -1.108  -1.037  -1.185  -0.869  -0.762  -1.064  -0.954  -0.876  -0.995
224   P        -1.408  -1.382  -1.267  -1.363  -1.322  -1.174  -1.276  -1.251  -1.072
225   C        -2.008  -2.013  -1.830  -1.734  -1.723  -1.463  -1.490  -1.489  -1.266
226   D        -2.008  -2.008  -1.833  -1.858  -1.896  -1.640  -1.490  -1.485  -1.268
227   L        -1.408  -1.439  -1.260  -1.430  -1.495  -1.241  -1.276  -1.293  -1.067
228   N        -2.308  -2.292  -2.066  -1.993  -1.995  -1.664  -1.597  -1.581  -1.334
229   V        -1.708  -1.720  -1.564  -1.648  -1.655  -1.467  -1.383  -1.387  -1.180
230   T        -0.566  -0.542  -0.775  -0.265  -0.234  -0.562  -0.526  -0.496  -0.765
231   W         0.319   0.369   0.310   0.636   0.711   0.578   0.116   0.203   0.050
232   V        -0.266  -0.238  -0.336  -0.358  -0.319  -0.469  -0.419  -0.380  -0.509
233   K        -0.266  -0.239  -0.341  -0.366  -0.327  -0.478  -0.419  -0.383  -0.519
234   T         0.019   0.014  -0.264   0.201   0.198  -0.257   0.009   0.002  -0.401
235   I        -1.295  -1.260  -1.228  -0.994  -0.948  -0.905  -1.168  -1.128  -1.039
236   L         0.147   0.137   0.233  -0.140  -0.165  -0.007  -0.205  -0.228  -0.099
237   T        -1.295  -1.327  -1.239  -1.383  -1.432  -1.324  -1.168  -1.196  -1.049
238   K         0.640   0.688   0.420   0.753   0.817   0.454   0.651   0.723   0.254
239   S         0.640   0.558   0.405   0.649   0.549   0.354   0.651   0.522   0.227
240   E        -0.566  -0.618  -0.787  -0.362  -0.451  -0.755  -0.526  -0.590  -0.779
241   R         1.292   1.299   1.372   1.478   1.486   1.589   1.400   1.409   1.515
242   P         1.292   1.299   1.372   1.405   1.413   1.521   1.400   1.409   1.515
243   E         0.147   0.141   0.238   0.053   0.039   0.179  -0.205  -0.219  -0.089
244   L         1.292   1.299   1.372   1.189   1.198   1.318   1.400   1.409   1.515
245   T        -0.266  -0.317  -0.354  -0.307  -0.391  -0.451  -0.419  -0.492  -0.535
246   S         0.019   0.068  -0.258   0.074   0.136  -0.311   0.009   0.077  -0.392
247   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
248   Q        -0.995  -1.016  -0.890  -0.919  -0.945  -0.751  -1.061  -1.079  -0.899
249   N        -0.808  -0.815  -0.836  -0.594  -0.594  -0.662  -0.847  -0.847  -0.839
250   V         0.319   0.332   0.299   0.171   0.188   0.119   0.116   0.138   0.029
251   V         1.292   1.299   1.372   1.200   1.207   1.328   1.400   1.409   1.515
252   T         0.019  -0.086  -0.278   0.034  -0.119  -0.430   0.009  -0.138  -0.422
253   G         1.292   1.299   1.372   1.280   1.291   1.403   1.400   1.409   1.515
254   G         1.292   1.299   1.372   1.280   1.291   1.403   1.400   1.409   1.515
255   R         1.292   1.299   1.372   1.478   1.486   1.589   1.400   1.409   1.515
256   A        -0.266  -0.351  -0.357  -0.362  -0.488  -0.527  -0.419  -0.530  -0.540
257   L         0.640   0.637   0.413   0.648   0.646   0.372   0.651   0.646   0.242
258   K         1.292   1.299   1.372   1.310   1.324   1.431   1.400   1.409   1.515
259   D        -0.395  -0.383  -0.375  -0.351  -0.354  -0.335  -0.633  -0.629  -0.572
260   K         1.292   1.299   1.372   1.310   1.324   1.431   1.400   1.409   1.515
261   E         1.292   1.299   1.372   1.360   1.370   1.478   1.400   1.409   1.515
262   T        -0.566  -0.493  -0.771  -0.201  -0.112  -0.468  -0.526  -0.435  -0.760
263   F         1.292   1.299   1.372   1.489   1.496   1.599   1.400   1.409   1.515
264   E         0.147   0.176   0.247   0.053   0.103   0.195  -0.205  -0.152  -0.072
265   K        -0.566  -0.587  -0.777  -0.347  -0.367  -0.663  -0.526  -0.554  -0.768
266   L         0.147   0.141   0.238  -0.140  -0.156   0.001  -0.205  -0.219  -0.089
267   L        -0.995  -0.945  -0.876  -1.026  -0.965  -0.848  -1.061  -1.002  -0.883
268   S        -1.595  -1.536  -1.532  -1.306  -1.227  -1.256  -1.276  -1.219  -1.154
269   P         1.292   1.299   1.372   1.405   1.413   1.521   1.400   1.409   1.515
270   L         1.292   1.299   1.372   1.189   1.198   1.318   1.400   1.409   1.515
271   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
272   D         0.019   0.095  -0.259   0.242   0.338  -0.184   0.009   0.114  -0.394
273   V        -1.295  -1.278  -1.235  -1.313  -1.282  -1.281  -1.168  -1.149  -1.044
274   L         1.292   1.299   1.372   1.189   1.198   1.318   1.400   1.409   1.515
275   H        -0.508  -0.488  -0.409  -0.460  -0.431  -0.301  -0.740  -0.713  -0.608
276   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
277   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
278   I         0.319   0.360   0.297   0.235   0.299   0.154   0.116   0.188   0.025
279   G         1.292   1.299   1.372   1.280   1.291   1.403   1.400   1.409   1.515
280   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
281   T         0.092   0.103   0.228  -0.165  -0.139   0.059  -0.312  -0.294  -0.109
282   R         1.292   1.299   1.372   1.478   1.486   1.589   1.400   1.409   1.515
283   A         0.319   0.296   0.276  -0.024  -0.060  -0.113   0.116   0.072  -0.015
284   S         0.640   0.612   0.410   0.450   0.420   0.125   0.651   0.608   0.236
285   V         1.292   1.299   1.372   1.200   1.207   1.328   1.400   1.409   1.515
286   D         1.292   1.299   1.372   1.377   1.383   1.494   1.400   1.409   1.515
287   N         0.319   0.301   0.289   0.220   0.190   0.176   0.116   0.082   0.010
288   G         1.292   1.299   1.372   1.280   1.291   1.403   1.400   1.409   1.515
289   L        -0.266  -0.317  -0.354  -0.011  -0.090  -0.174  -0.419  -0.492  -0.535
290   C         0.147   0.141   0.238   0.106   0.083   0.179  -0.205  -0.219  -0.089
291   D         1.292   1.299   1.372   1.377   1.383   1.494   1.400   1.409   1.515
292   N         1.292   1.299   1.372   1.459   1.465   1.571   1.400   1.409   1.515
293   S         1.292   1.299   1.372   1.195   1.203   1.323   1.400   1.409   1.515
294   L         1.292   1.299   1.372   1.189   1.198   1.318   1.400   1.409   1.515
295   Q         1.292   1.299   1.372   1.506   1.515   1.615   1.400   1.409   1.515
296   I         0.092   0.103   0.228  -0.225  -0.207   0.000  -0.312  -0.294  -0.109
297   G         1.292   1.299   1.372   1.280   1.291   1.403   1.400   1.409   1.515
298   Q         1.292   1.299   1.372   1.506   1.515   1.615   1.400   1.409   1.515
299   T         1.292   1.299   1.372   1.384   1.391   1.500   1.400   1.409   1.515
300   G         1.292   1.299   1.372   1.280   1.291   1.403   1.400   1.409   1.515
301   K         1.292   1.299   1.372   1.310   1.324   1.431   1.400   1.409   1.515
302   V         0.092   0.099   0.226  -0.225  -0.221  -0.007  -0.312  -0.302  -0.113
303   V         0.640   0.558   0.405   0.631   0.523   0.303   0.651   0.522   0.227
304   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
305   P         1.292   1.299   1.372   1.405   1.413   1.521   1.400   1.409   1.515
306   N        -1.295  -1.333  -1.236  -1.043  -1.099  -0.940  -1.168  -1.199  -1.046
307   L         1.292   1.299   1.372   1.189   1.198   1.318   1.400   1.409   1.515
308   Y         1.292   1.299   1.372   1.559   1.567   1.664   1.400   1.409   1.515
309   I         0.640   0.673   0.419   0.714   0.752   0.381   0.651   0.701   0.252
310   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
311   I        -0.566  -0.578  -0.790  -0.559  -0.579  -0.964  -0.526  -0.539  -0.782
312   G         1.292   1.299   1.372   1.280   1.291   1.403   1.400   1.409   1.515
313   V         0.319   0.318   0.294   0.235   0.226   0.148   0.116   0.112   0.020
314   S         0.640   0.558   0.405   0.637   0.533   0.325   0.651   0.522   0.227
315   G         1.292   1.299   1.372   1.280   1.291   1.403   1.400   1.409   1.515
316   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
317   V         0.640   0.612   0.410   0.716   0.675   0.368   0.651   0.608   0.236
318   Q         1.292   1.299   1.372   1.506   1.515   1.615   1.400   1.409   1.515
319   H         1.292   1.299   1.372   1.588   1.595   1.692   1.400   1.409   1.515
320   L         1.292   1.299   1.372   1.189   1.198   1.318   1.400   1.409   1.515
321   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
322   G         1.292   1.299   1.372   1.280   1.291   1.403   1.400   1.409   1.515
323   M         0.147   0.134   0.235   0.217   0.177   0.299  -0.205  -0.233  -0.096
324   K         1.292   1.299   1.372   1.310   1.324   1.431   1.400   1.409   1.515
325   D         1.292   1.299   1.372   1.377   1.383   1.494   1.400   1.409   1.515
326   S         0.319   0.362   0.302   0.080   0.156  -0.002   0.116   0.190   0.035
327   K         1.292   1.299   1.372   1.310   1.324   1.431   1.400   1.409   1.515
328   V         0.319   0.362   0.302   0.200   0.262   0.166   0.116   0.190   0.035
329   I         1.292   1.299   1.372   1.299   1.303   1.420   1.400   1.409   1.515
330   V         0.147   0.141   0.238  -0.273  -0.292  -0.152  -0.205  -0.219  -0.089
331   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
332   I         1.292   1.299   1.372   1.299   1.303   1.420   1.400   1.409   1.515
333   N         1.292   1.299   1.372   1.459   1.465   1.571   1.400   1.409   1.515
334   N        -0.266  -0.351  -0.357  -0.161  -0.267  -0.268  -0.419  -0.530  -0.540
335   D         1.292   1.299   1.372   1.377   1.383   1.494   1.400   1.409   1.515
336   P        -0.266  -0.307  -0.347  -0.249  -0.290  -0.422  -0.419  -0.462  -0.526
337   D        -0.395  -0.446  -0.372  -0.378  -0.438  -0.310  -0.633  -0.686  -0.568
338   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
339   P         1.292   1.299   1.372   1.405   1.413   1.521   1.400   1.409   1.515
340   I         1.292   1.299   1.372   1.299   1.303   1.420   1.400   1.409   1.515
341   F         1.292   1.299   1.372   1.489   1.496   1.599   1.400   1.409   1.515
342   N        -0.881  -0.868  -0.849  -0.643  -0.625  -0.597  -0.954  -0.938  -0.857
343   V         0.019  -0.018  -0.267   0.083   0.031  -0.315   0.009  -0.046  -0.406
344   A         1.292   1.299   1.372   1.036   1.051   1.175   1.400   1.409   1.515
345   D         1.292   1.299   1.372   1.377   1.383   1.494   1.400   1.409   1.515
346   Y        -0.395  -0.361  -0.373  -0.425  -0.387  -0.366  -0.633  -0.597  -0.567
347   G         0.640   0.637   0.413   0.674   0.674   0.304   0.651   0.646   0.242
348   L         0.640   0.558   0.405   0.620   0.514   0.293   0.651   0.522   0.227
349   Q         0.640   0.612   0.410   0.662   0.629   0.383   0.651   0.608   0.236
350   G        -0.266  -0.238  -0.336  -0.371  -0.310  -0.503  -0.419  -0.372  -0.510
351   D         1.292   1.299   1.372   1.377   1.383   1.494   1.400   1.409   1.515
352   L         0.019   0.055  -0.256   0.040   0.086  -0.370   0.009   0.059  -0.389
353   Y        -0.581  -0.581  -0.437  -0.430  -0.430  -0.221  -0.847  -0.844  -0.646
354   K        -0.266  -0.264  -0.346  -0.189  -0.193  -0.320  -0.419  -0.423  -0.524
355   I        -1.408  -1.377  -1.257  -1.692  -1.628  -1.439  -1.276  -1.246  -1.065
356   V         0.019   0.047  -0.261   0.050   0.084  -0.373   0.009   0.049  -0.397
357   P         1.292   1.299   1.372   1.405   1.413   1.521   1.400   1.409   1.515
358   E         1.292   1.299   1.372   1.360   1.370   1.478   1.400   1.409   1.515
359   L         1.292   1.299   1.372   1.189   1.198   1.318   1.400   1.409   1.515
360   T         1.292   1.299   1.372   1.384   1.391   1.500   1.400   1.409   1.515
361   E         0.640   0.680   0.417   0.814   0.863   0.520   0.651   0.711   0.249
362   K         1.292   1.299   1.372   1.310   1.324   1.431   1.400   1.409   1.515
363   L         0.640   0.666   0.416   0.606   0.639   0.279   0.651   0.690   0.247
364   G         0.426   0.432   0.328   0.432   0.442   0.249   0.304   0.313   0.084
365   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12480
Output conservation file - output/Q12480
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
