1     M         1.613   1.619   1.673   1.873   1.881   1.959   1.759   1.765   1.846
2     I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     S         0.792   0.723   0.614   0.532   0.449   0.312   0.770   0.654   0.445
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    D         0.033  -0.015  -0.144   0.334   0.256   0.052  -0.021  -0.089  -0.273
17    Y        -1.230  -1.236  -1.193  -0.916  -0.934  -0.852  -1.010  -1.012  -0.941
18    D        -0.809  -0.836  -0.786  -0.600  -0.641  -0.554  -0.812  -0.833  -0.756
19    A         1.613   1.619   1.673   1.722   1.723   1.810   1.759   1.765   1.846
20    L         1.613   1.619   1.673   1.467   1.478   1.558   1.759   1.765   1.846
21    L        -1.230  -1.224  -1.203  -1.141  -1.130  -1.064  -1.010  -1.002  -0.950
22    Q        -0.230  -0.272  -0.246  -0.208  -0.264  -0.228  -0.417  -0.465  -0.424
23    F         1.613   1.619   1.673   1.862   1.871   1.948   1.759   1.765   1.846
24    N        -0.809  -0.839  -0.796  -0.976  -0.986  -0.886  -0.812  -0.836  -0.766
25    K        -0.809  -0.839  -0.796  -0.640  -0.680  -0.599  -0.812  -0.836  -0.766
26    K         0.033  -0.030  -0.152   0.184   0.065  -0.172  -0.021  -0.110  -0.284
27    P        -0.651  -0.695  -0.752  -0.405  -0.483  -0.571  -0.615  -0.665  -0.716
28    V         1.613   1.619   1.673   1.728   1.733   1.816   1.759   1.765   1.846
29    S         0.033  -0.015  -0.144  -0.212  -0.269  -0.439  -0.021  -0.089  -0.273
30    Q        -0.809  -0.779  -0.788  -0.718  -0.684  -0.693  -0.812  -0.779  -0.758
31    E        -0.230  -0.242  -0.247  -0.217  -0.244  -0.286  -0.417  -0.432  -0.427
32    M         1.613   1.619   1.673   1.873   1.881   1.959   1.759   1.765   1.846
33    I         0.454   0.486   0.483   0.400   0.460   0.434   0.177   0.235   0.202
34    Q        -1.230  -1.221  -1.189  -1.068  -1.041  -1.029  -1.010  -0.999  -0.938
35    F         0.792   0.785   0.618   1.121   1.110   0.866   0.770   0.756   0.452
36    L         1.613   1.619   1.673   1.467   1.478   1.558   1.759   1.765   1.846
37    A         0.454   0.473   0.464   0.429   0.452   0.426   0.177   0.211   0.165
38    T        -0.388  -0.381  -0.310  -0.761  -0.747  -0.642  -0.615  -0.602  -0.505
39    S         0.033  -0.030  -0.152   0.080  -0.021  -0.268  -0.021  -0.110  -0.284
40    T         0.792   0.723   0.614   0.921   0.822   0.652   0.770   0.654   0.445
41    A        -0.809  -0.789  -0.778  -1.029  -1.016  -0.971  -0.812  -0.790  -0.748
42    S         0.033  -0.037  -0.175  -0.224  -0.315  -0.498  -0.021  -0.119  -0.316
43    I         0.454   0.477   0.478   0.417   0.457   0.437   0.177   0.218   0.191
44    I         1.613   1.619   1.673   1.690   1.707   1.779   1.759   1.765   1.846
45    K        -0.230  -0.220  -0.242  -0.276  -0.262  -0.340  -0.417  -0.405  -0.420
46    I        -0.388  -0.379  -0.310  -0.324  -0.298  -0.200  -0.615  -0.601  -0.505
47    R        -0.809  -0.797  -0.793  -0.652  -0.629  -0.621  -0.812  -0.795  -0.763
48    E        -1.230  -1.211  -1.192  -1.116  -1.095  -1.074  -1.010  -0.988  -0.940
49    N        -0.809  -0.789  -0.774  -1.071  -1.028  -0.987  -0.812  -0.789  -0.745
50    N        -0.809  -0.797  -0.793  -0.596  -0.568  -0.560  -0.812  -0.795  -0.763
51    N        -0.913  -0.908  -0.832  -0.815  -0.808  -0.692  -0.911  -0.902  -0.801
52    P        -0.281  -0.255  -0.251  -0.449  -0.395  -0.427  -0.466  -0.428  -0.423
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -0.281  -0.282  -0.257  -0.382  -0.405  -0.373  -0.466  -0.467  -0.432
55    -         0.350   0.357   0.423   0.349   0.352   0.456  -0.021  -0.011   0.086
56    -        -0.913  -0.907  -0.832  -1.126  -1.126  -1.000  -0.911  -0.902  -0.801
57    -        -0.281  -0.270  -0.248  -0.250  -0.234  -0.206  -0.466  -0.449  -0.419
58    -        -0.281  -0.250  -0.266  -0.586  -0.521  -0.622  -0.466  -0.421  -0.444
59    -        -0.913  -0.907  -0.832  -0.998  -0.987  -0.873  -0.911  -0.902  -0.801
60    -        -0.281  -0.282  -0.259  -0.695  -0.693  -0.635  -0.466  -0.467  -0.434
61    -        -0.913  -0.907  -0.832  -1.047  -1.061  -0.921  -0.911  -0.902  -0.801
62    -         0.350   0.357   0.423   0.013   0.042   0.155  -0.021  -0.011   0.086
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -0.281  -0.301  -0.285  -0.490  -0.526  -0.553  -0.466  -0.492  -0.470
76    I        -0.651  -0.690  -0.737  -0.813  -0.847  -0.873  -0.615  -0.659  -0.698
77    Q        -1.230  -1.256  -1.214  -0.933  -0.985  -0.906  -1.010  -1.031  -0.960
78    G        -1.651  -1.642  -1.565  -1.341  -1.339  -1.211  -1.208  -1.196  -1.095
79    C        -0.809  -0.788  -0.777  -0.614  -0.588  -0.596  -0.812  -0.788  -0.748
80    R        -1.651  -1.642  -1.565  -1.452  -1.426  -1.320  -1.208  -1.196  -1.095
81    P        -0.809  -0.783  -0.788  -1.077  -1.036  -1.057  -0.812  -0.783  -0.759
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    P        -0.230  -0.177  -0.229  -0.180  -0.103  -0.177  -0.417  -0.346  -0.400
84    D        -0.230  -0.247  -0.258  -0.594  -0.607  -0.571  -0.417  -0.443  -0.440
85    L         1.613   1.619   1.673   1.467   1.478   1.558   1.759   1.765   1.846
86    S        -1.230  -1.235  -1.199  -1.332  -1.326  -1.230  -1.010  -1.012  -0.947
87    I        -1.651  -1.642  -1.565  -1.330  -1.322  -1.201  -1.208  -1.196  -1.095
88    F         1.613   1.619   1.673   1.862   1.871   1.948   1.759   1.765   1.846
89    I         1.613   1.619   1.673   1.690   1.707   1.779   1.759   1.765   1.846
90    K         0.454   0.423   0.444   0.219   0.141   0.111   0.177   0.116   0.127
91    N        -1.230  -1.239  -1.203  -1.151  -1.149  -1.118  -1.010  -1.015  -0.951
92    V         0.792   0.792   0.621   0.708   0.710   0.463   0.770   0.769   0.458
93    V         0.350   0.359   0.426   0.210   0.228   0.332  -0.021  -0.006   0.092
94    I        -1.651  -1.642  -1.565  -1.414  -1.399  -1.283  -1.208  -1.196  -1.095
95    Q        -0.809  -0.797  -0.793  -0.879  -0.897  -0.830  -0.812  -0.795  -0.763
96    S         1.613   1.619   1.673   1.257   1.271   1.351   1.759   1.765   1.846
97    N         1.613   1.619   1.673   1.682   1.698   1.770   1.759   1.765   1.846
98    V         1.613   1.619   1.673   1.728   1.733   1.816   1.759   1.765   1.846
99    Q         1.613   1.619   1.673   1.785   1.791   1.873   1.759   1.765   1.846
100   T         0.792   0.723   0.614   0.922   0.824   0.654   0.770   0.654   0.445
101   P         1.613   1.619   1.673   1.760   1.765   1.847   1.759   1.765   1.846
102   T         1.613   1.619   1.673   1.682   1.691   1.770   1.759   1.765   1.846
103   L         1.613   1.619   1.673   1.467   1.478   1.558   1.759   1.765   1.846
104   M         1.613   1.619   1.673   1.873   1.881   1.959   1.759   1.765   1.846
105   A         0.033  -0.037  -0.175   0.110  -0.024  -0.293  -0.021  -0.119  -0.316
106   T         0.350   0.356   0.424  -0.141  -0.141  -0.040  -0.021  -0.012   0.088
107   S        -0.651  -0.607  -0.709  -0.864  -0.794  -0.983  -0.615  -0.561  -0.666
108   V         0.792   0.836   0.629   0.961   1.018   0.710   0.770   0.839   0.472
109   Y         1.613   1.619   1.673   1.834   1.840   1.920   1.759   1.765   1.846
110   L         1.613   1.619   1.673   1.467   1.478   1.558   1.759   1.765   1.846
111   N        -0.651  -0.695  -0.752  -0.490  -0.559  -0.651  -0.615  -0.665  -0.716
112   K         0.454   0.423   0.444   0.440   0.382   0.401   0.177   0.116   0.127
113   L         1.613   1.619   1.673   1.467   1.478   1.558   1.759   1.765   1.846
114   K         0.454   0.425   0.443   0.453   0.393   0.406   0.177   0.122   0.125
115   S         0.454   0.498   0.494  -0.024   0.053   0.042   0.177   0.257   0.222
116   V        -1.230  -1.243  -1.204  -1.322  -1.338  -1.316  -1.010  -1.019  -0.951
117   I         0.792   0.792   0.621   0.700   0.705   0.449   0.770   0.769   0.458
118   P         0.792   0.723   0.614   1.011   0.910   0.747   0.770   0.654   0.445
119   K        -0.809  -0.797  -0.793  -0.648  -0.635  -0.605  -0.812  -0.795  -0.763
120   N         0.033   0.038  -0.142   0.154   0.165  -0.133  -0.021  -0.013  -0.269
121   V         0.454   0.462   0.462   0.429   0.433   0.421   0.177   0.191   0.161
122   Y        -1.230  -1.182  -1.199  -0.899  -0.829  -0.841  -1.010  -0.960  -0.947
123   G         1.613   1.619   1.673   1.882   1.888   1.968   1.759   1.765   1.846
124   I        -0.230  -0.272  -0.246  -0.165  -0.239  -0.224  -0.417  -0.465  -0.424
125   N        -0.651  -0.707  -0.758  -0.384  -0.477  -0.564  -0.615  -0.679  -0.721
126   T         0.454   0.423   0.444   0.497   0.449   0.490   0.177   0.116   0.127
127   T         1.613   1.619   1.673   1.682   1.691   1.770   1.759   1.765   1.846
128   R         0.033  -0.037  -0.175   0.256   0.141  -0.073  -0.021  -0.119  -0.316
129   H         1.613   1.619   1.673   1.856   1.867   1.943   1.759   1.765   1.846
130   R         1.613   1.619   1.673   1.751   1.753   1.839   1.759   1.765   1.846
131   I         1.613   1.619   1.673   1.690   1.707   1.779   1.759   1.765   1.846
132   F         1.613   1.619   1.673   1.862   1.871   1.948   1.759   1.765   1.846
133   L         0.792   0.811   0.626   0.700   0.730   0.456   0.770   0.799   0.466
134   G        -0.230  -0.213  -0.248  -0.193  -0.182  -0.278  -0.417  -0.404  -0.426
135   C        -0.230  -0.232  -0.242  -0.196  -0.211  -0.248  -0.417  -0.416  -0.418
136   L         1.613   1.619   1.673   1.467   1.478   1.558   1.759   1.765   1.846
137   I         1.613   1.619   1.673   1.690   1.707   1.779   1.759   1.765   1.846
138   L         0.033   0.067  -0.116   0.021   0.069  -0.172  -0.021   0.027  -0.233
139   A         0.792   0.836   0.629   0.873   0.933   0.562   0.770   0.839   0.472
140   A         1.613   1.619   1.673   1.722   1.723   1.810   1.759   1.765   1.846
141   K         1.613   1.619   1.673   1.722   1.736   1.810   1.759   1.765   1.846
142   T        -0.809  -0.836  -0.786  -1.042  -1.042  -0.944  -0.812  -0.833  -0.756
143   L         1.613   1.619   1.673   1.467   1.478   1.558   1.759   1.765   1.846
144   N         1.613   1.619   1.673   1.682   1.698   1.770   1.759   1.765   1.846
145   D         1.613   1.619   1.673   1.825   1.830   1.912   1.759   1.765   1.846
146   S         1.613   1.619   1.673   1.257   1.271   1.351   1.759   1.765   1.846
147   S         1.613   1.619   1.673   1.257   1.271   1.351   1.759   1.765   1.846
148   P         1.613   1.619   1.673   1.760   1.765   1.847   1.759   1.765   1.846
149   W        -0.809  -0.787  -0.789  -0.753  -0.711  -0.672  -0.812  -0.786  -0.759
150   N         1.613   1.619   1.673   1.682   1.698   1.770   1.759   1.765   1.846
151   K         1.613   1.619   1.673   1.722   1.736   1.810   1.759   1.765   1.846
152   H         1.613   1.619   1.673   1.856   1.867   1.943   1.759   1.765   1.846
153   W         1.613   1.619   1.673   1.957   1.966   2.042   1.759   1.765   1.846
154   T         0.454   0.423   0.444   0.389   0.326   0.351   0.177   0.116   0.127
155   T        -0.651  -0.690  -0.737  -0.613  -0.697  -0.809  -0.615  -0.659  -0.698
156   Y         1.613   1.619   1.673   1.834   1.840   1.920   1.759   1.765   1.846
157   T         1.613   1.619   1.673   1.682   1.691   1.770   1.759   1.765   1.846
158   E        -0.651  -0.707  -0.758  -0.305  -0.399  -0.474  -0.615  -0.679  -0.721
159   G         0.033  -0.037  -0.175   0.441   0.338   0.135  -0.021  -0.119  -0.316
160   L         0.792   0.723   0.614   0.612   0.501   0.277   0.770   0.654   0.445
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   L         0.350   0.358   0.425   0.151   0.179   0.291  -0.021  -0.009   0.091
169   R        -0.230  -0.247  -0.258  -0.491  -0.554  -0.559  -0.417  -0.443  -0.440
170   I        -0.230  -0.266  -0.238  -0.431  -0.474  -0.420  -0.417  -0.456  -0.414
171   R        -0.651  -0.707  -0.758  -0.355  -0.449  -0.524  -0.615  -0.679  -0.721
172   E         0.792   0.811   0.626   1.044   1.069   0.804   0.770   0.799   0.466
173   V         1.613   1.619   1.673   1.728   1.733   1.816   1.759   1.765   1.846
174   N         1.613   1.619   1.673   1.682   1.698   1.770   1.759   1.765   1.846
175   T        -0.230  -0.196  -0.237  -0.399  -0.358  -0.375  -0.417  -0.374  -0.412
176   I        -0.388  -0.379  -0.310  -0.376  -0.357  -0.254  -0.615  -0.601  -0.505
177   E         1.613   1.619   1.673   1.785   1.795   1.873   1.759   1.765   1.846
178   R         0.454   0.423   0.444   0.453   0.388   0.408   0.177   0.116   0.127
179   E         0.454   0.423   0.444   0.513   0.452   0.473   0.177   0.116   0.127
180   L         1.613   1.619   1.673   1.467   1.478   1.558   1.759   1.765   1.846
181   L         0.792   0.836   0.629   0.700   0.764   0.461   0.770   0.839   0.472
182   E        -1.651  -1.642  -1.565  -1.321  -1.288  -1.192  -1.208  -1.196  -1.095
183   Y         0.033   0.074  -0.113   0.001   0.061  -0.198  -0.021   0.037  -0.229
184   L         0.792   0.811   0.626   0.737   0.764   0.519   0.770   0.799   0.466
185   N        -0.809  -0.779  -0.788  -0.827  -0.769  -0.818  -0.812  -0.779  -0.758
186   W         1.613   1.619   1.673   1.957   1.966   2.042   1.759   1.765   1.846
187   D        -0.651  -0.655  -0.714  -0.349  -0.359  -0.460  -0.615  -0.619  -0.672
188   V        -0.651  -0.589  -0.708  -0.708  -0.617  -0.785  -0.615  -0.540  -0.666
189   R         0.350   0.359   0.426   0.221   0.237   0.344  -0.021  -0.006   0.092
190   I        -0.230  -0.209  -0.236  -0.189  -0.156  -0.182  -0.417  -0.387  -0.412
191   T        -0.651  -0.619  -0.719  -0.617  -0.565  -0.763  -0.615  -0.575  -0.678
192   T        -1.230  -1.207  -1.184  -0.916  -0.885  -0.847  -1.010  -0.984  -0.933
193   P        -0.809  -0.790  -0.776  -0.588  -0.571  -0.527  -0.812  -0.790  -0.747
194   D         0.350   0.359   0.426   0.349   0.361   0.468  -0.021  -0.006   0.092
195   L         1.613   1.619   1.673   1.467   1.478   1.558   1.759   1.765   1.846
196   I        -0.230  -0.235  -0.255  -0.168  -0.176  -0.194  -0.417  -0.429  -0.436
197   D        -1.651  -1.642  -1.565  -1.436  -1.418  -1.305  -1.208  -1.196  -1.095
198   S        -1.230  -1.239  -1.203  -1.303  -1.303  -1.200  -1.010  -1.015  -0.951
199   L         0.792   0.785   0.618   0.737   0.730   0.508   0.770   0.756   0.452
200   S        -1.230  -1.224  -1.203  -1.270  -1.267  -1.164  -1.010  -1.002  -0.950
201   Y        -0.809  -0.801  -0.784  -0.573  -0.563  -0.519  -0.812  -0.799  -0.754
202   F         1.613   1.619   1.673   1.862   1.871   1.948   1.759   1.765   1.846
203   L         1.613   1.619   1.673   1.467   1.478   1.558   1.759   1.765   1.846
204   G        -1.651  -1.642  -1.565  -1.499  -1.503  -1.367  -1.208  -1.196  -1.095
205   P         0.792   0.836   0.629   0.910   0.975   0.599   0.770   0.839   0.472
206   I         1.613   1.619   1.673   1.690   1.707   1.779   1.759   1.765   1.846
207   K        -0.651  -0.655  -0.714  -0.431  -0.438  -0.529  -0.615  -0.619  -0.672
208   E        -1.230  -1.211  -1.192  -0.947  -0.928  -0.889  -1.010  -0.988  -0.940
209   Q        -0.651  -0.678  -0.748  -0.354  -0.398  -0.507  -0.615  -0.646  -0.710
210   L        -0.118  -0.130  -0.189  -0.196  -0.212  -0.287  -0.235  -0.251  -0.336
211   F        -0.814  -0.814  -0.783  -0.793  -0.788  -0.762  -0.804  -0.801  -0.749
212   L        -1.319  -1.314  -1.235  -1.256  -1.248  -1.127  -1.089  -1.080  -0.978
213   Q        -0.309  -0.302  -0.277  -0.282  -0.275  -0.225  -0.520  -0.509  -0.463
214   R        -0.814  -0.789  -0.791  -0.606  -0.567  -0.585  -0.804  -0.773  -0.758
215   R        -0.814  -0.789  -0.791  -0.878  -0.835  -0.865  -0.804  -0.773  -0.758
216   Q        -1.319  -1.314  -1.235  -1.070  -1.069  -0.944  -1.089  -1.080  -0.978
217   E        -0.118  -0.123  -0.184   0.090   0.077  -0.024  -0.235  -0.241  -0.330
218   M        -0.814  -0.793  -0.777  -0.459  -0.427  -0.406  -0.804  -0.777  -0.743
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   N        -0.118  -0.144  -0.211  -0.137  -0.178  -0.341  -0.235  -0.271  -0.368
233   A         1.613   1.619   1.673   1.703   1.708   1.791   1.759   1.765   1.846
234   P        -0.118  -0.130  -0.189   0.101   0.085  -0.000  -0.235  -0.251  -0.336
235   S        -0.309  -0.297  -0.265  -0.657  -0.639  -0.570  -0.520  -0.504  -0.449
236   P        -1.319  -1.314  -1.235  -1.348  -1.330  -1.218  -1.089  -1.080  -0.978
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   G        -0.281  -0.288  -0.270  -0.174  -0.192  -0.185  -0.466  -0.475  -0.451
245   Q         0.589   0.589   0.549   0.680   0.678   0.593   0.424   0.423   0.326
246   L        -0.814  -0.800  -0.783  -0.728  -0.701  -0.706  -0.804  -0.785  -0.750
247   K        -0.814  -0.822  -0.795  -0.665  -0.680  -0.639  -0.804  -0.810  -0.762
248   E        -0.809  -0.779  -0.788  -0.610  -0.573  -0.570  -0.812  -0.779  -0.758
249   Y        -0.230  -0.235  -0.255  -0.041  -0.066  -0.071  -0.417  -0.429  -0.436
250   I        -1.230  -1.239  -1.203  -1.296  -1.310  -1.284  -1.010  -1.015  -0.951
251   N        -0.809  -0.793  -0.783  -0.740  -0.708  -0.698  -0.812  -0.794  -0.754
252   H        -0.651  -0.660  -0.719  -0.453  -0.460  -0.614  -0.615  -0.626  -0.678
253   R        -1.230  -1.211  -1.192  -1.126  -1.102  -1.088  -1.010  -0.988  -0.940
254   R        -0.814  -0.809  -0.783  -0.619  -0.617  -0.576  -0.804  -0.796  -0.750
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   P        -0.309  -0.310  -0.280  -0.295  -0.295  -0.244  -0.520  -0.517  -0.467
257   V        -0.814  -0.796  -0.781  -0.622  -0.601  -0.569  -0.804  -0.781  -0.748
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   S        -0.809  -0.783  -0.788  -0.740  -0.710  -0.722  -0.812  -0.783  -0.759
260   H        -1.230  -1.224  -1.203  -0.816  -0.820  -0.778  -1.010  -1.002  -0.950
261   S         0.792   0.845   0.646   0.511   0.583   0.321   0.770   0.852   0.503
262   R        -0.651  -0.673  -0.739  -0.548  -0.597  -0.738  -0.615  -0.640  -0.701
263   T         0.033  -0.030  -0.152  -0.231  -0.316  -0.478  -0.021  -0.110  -0.284
264   S        -0.651  -0.595  -0.706  -0.848  -0.765  -0.886  -0.615  -0.546  -0.663
265   S         0.454   0.473   0.464  -0.003   0.026   0.023   0.177   0.211   0.165
266   A        -1.651  -1.642  -1.565  -1.530  -1.510  -1.397  -1.208  -1.196  -1.095
267   I        -1.230  -1.211  -1.192  -0.870  -0.842  -0.823  -1.010  -0.988  -0.940
268   S         0.792   0.785   0.618   0.532   0.528   0.318   0.770   0.756   0.452
269   V        -0.388  -0.383  -0.311  -0.751  -0.748  -0.632  -0.615  -0.605  -0.506
270   P        -0.651  -0.637  -0.718  -0.555  -0.531  -0.708  -0.615  -0.599  -0.677
271   S         0.792   0.785   0.618   0.527   0.523   0.308   0.770   0.756   0.452
272   L        -0.230  -0.252  -0.231  -0.431  -0.453  -0.410  -0.417  -0.434  -0.400
273   T        -1.230  -1.213  -1.190  -1.225  -1.195  -1.177  -1.010  -0.991  -0.939
274   S         0.033  -0.037  -0.175  -0.148  -0.231  -0.375  -0.021  -0.119  -0.316
275   M        -0.651  -0.667  -0.720  -0.794  -0.806  -0.834  -0.615  -0.634  -0.679
276   A        -1.230  -1.186  -1.186  -1.072  -1.006  -1.010  -1.010  -0.964  -0.935
277   T         0.454   0.462   0.462  -0.024  -0.008  -0.005   0.177   0.191   0.161
278   V        -0.651  -0.707  -0.758  -0.662  -0.747  -0.790  -0.615  -0.679  -0.721
279   S        -1.230  -1.224  -1.203  -1.289  -1.275  -1.184  -1.010  -1.002  -0.950
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   T         0.350   0.359   0.426  -0.141  -0.102   0.009  -0.021  -0.006   0.092
287   T         0.033   0.022  -0.145  -0.233  -0.246  -0.472  -0.021  -0.036  -0.274
288   D        -1.230  -1.246  -1.205  -1.303  -1.319  -1.200  -1.010  -1.022  -0.952
289   S         0.454   0.423   0.444   0.016  -0.027   0.025   0.177   0.116   0.127
290   R         0.033  -0.030  -0.152  -0.177  -0.256  -0.395  -0.021  -0.110  -0.284
291   S         0.033   0.074  -0.113  -0.121  -0.062  -0.375  -0.021   0.037  -0.229
292   S         0.033   0.038  -0.142  -0.241  -0.232  -0.481  -0.021  -0.013  -0.269
293   L        -0.651  -0.695  -0.752  -0.746  -0.836  -0.897  -0.615  -0.665  -0.716
294   L        -0.651  -0.589  -0.708  -0.888  -0.810  -0.939  -0.615  -0.540  -0.666
295   A        -0.230  -0.251  -0.255  -0.581  -0.601  -0.549  -0.417  -0.447  -0.438
296   K        -0.651  -0.589  -0.708  -0.865  -0.780  -0.911  -0.615  -0.540  -0.666
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -         1.613   1.619   1.673   1.198   1.209   1.293   1.759   1.765   1.846
300   -        -0.814  -0.819  -0.783  -0.980  -0.981  -0.881  -0.804  -0.808  -0.749
301   -         0.387   0.376   0.426  -0.166  -0.176  -0.075   0.050   0.027   0.091
302   -         1.613   1.619   1.673   1.198   1.209   1.293   1.759   1.765   1.846
303   -         0.387   0.413   0.459  -0.080  -0.052   0.034   0.050   0.098   0.155
304   -        -0.814  -0.839  -0.808  -0.950  -0.991  -0.987  -0.804  -0.829  -0.776
305   -         0.702   0.744   0.587   0.242   0.310   0.041   0.620   0.689   0.395
306   -        -0.281  -0.299  -0.257  -0.627  -0.646  -0.554  -0.466  -0.490  -0.432
307   -         0.589   0.615   0.547   0.170   0.210   0.116   0.424   0.468   0.322
308   -        -0.913  -0.907  -0.832  -0.980  -0.989  -0.855  -0.911  -0.902  -0.801
309   -        -0.913  -0.907  -0.832  -1.243  -1.231  -1.115  -0.911  -0.902  -0.801
310   -        -0.913  -0.907  -0.832  -1.107  -1.108  -0.981  -0.911  -0.902  -0.801
311   -        -0.281  -0.279  -0.272  -0.385  -0.374  -0.418  -0.466  -0.462  -0.453
312   -         0.589   0.611   0.547   0.194   0.227   0.147   0.424   0.462   0.322
313   -        -0.281  -0.271  -0.248  -0.213  -0.197  -0.173  -0.466  -0.451  -0.419
314   -        -0.281  -0.252  -0.249  -0.431  -0.391  -0.374  -0.466  -0.423  -0.421
315   -        -0.913  -0.907  -0.832  -1.102  -1.082  -0.976  -0.911  -0.902  -0.801
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   P         1.613   1.619   1.673   1.716   1.724   1.804   1.759   1.765   1.846
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   S         0.589   0.589   0.549   0.266   0.266   0.219   0.424   0.423   0.326
324   L        -0.281  -0.265  -0.266  -0.283  -0.254  -0.296  -0.466  -0.442  -0.444
325   P        -0.913  -0.908  -0.832  -0.886  -0.882  -0.762  -0.911  -0.903  -0.801
326   L        -0.281  -0.281  -0.256  -0.488  -0.491  -0.445  -0.466  -0.465  -0.430
327   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   E        -0.281  -0.278  -0.254  -0.236  -0.233  -0.200  -0.466  -0.461  -0.428
329   S        -0.913  -0.908  -0.832  -1.008  -0.997  -0.883  -0.911  -0.903  -0.801
330   D        -0.281  -0.275  -0.251  -0.157  -0.150  -0.121  -0.466  -0.457  -0.423
331   N        -1.319  -1.314  -1.235  -1.267  -1.248  -1.138  -1.089  -1.080  -0.978
332   F        -0.309  -0.297  -0.276  -0.243  -0.225  -0.214  -0.520  -0.503  -0.462
333   N        -1.319  -1.314  -1.235  -1.256  -1.243  -1.127  -1.089  -1.080  -0.978
334   K        -0.118  -0.123  -0.184  -0.036  -0.040  -0.170  -0.235  -0.241  -0.330
335   K        -0.814  -0.814  -0.783  -0.854  -0.870  -0.836  -0.804  -0.801  -0.749
336   N        -1.319  -1.314  -1.235  -1.085  -1.083  -0.959  -1.089  -1.080  -0.978
337   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   V         0.589   0.572   0.527   0.578   0.558   0.465   0.424   0.392   0.285
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   P         1.613   1.619   1.673   1.787   1.791   1.874   1.759   1.765   1.846
341   L        -0.309  -0.350  -0.277  -0.472  -0.497  -0.391  -0.520  -0.565  -0.464
342   R        -1.319  -1.304  -1.235  -1.278  -1.250  -1.149  -1.089  -1.072  -0.978
343   N        -1.319  -1.304  -1.235  -1.223  -1.191  -1.095  -1.089  -1.072  -0.978
344   N        -0.309  -0.350  -0.282  -0.374  -0.418  -0.321  -0.520  -0.565  -0.470
345   N        -0.281  -0.300  -0.272  -0.676  -0.689  -0.639  -0.466  -0.492  -0.453
346   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
354   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
355   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   V         0.589   0.636   0.552   0.637   0.710   0.560   0.424   0.505   0.332
361   N         0.589   0.529   0.518   0.451   0.336   0.261   0.424   0.314   0.268
362   H        -0.281  -0.300  -0.272  -0.234  -0.273  -0.219  -0.466  -0.492  -0.453
363   I        -0.913  -0.902  -0.832  -1.062  -1.041  -0.936  -0.911  -0.897  -0.801
364   D        -0.281  -0.300  -0.272  -0.240  -0.264  -0.218  -0.466  -0.492  -0.453
365   V        -0.281  -0.300  -0.272  -0.307  -0.341  -0.307  -0.466  -0.492  -0.453
366   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
376   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   T        -0.281  -0.268  -0.266  -0.218  -0.202  -0.195  -0.466  -0.447  -0.445
381   I        -0.913  -0.907  -0.832  -0.791  -0.787  -0.669  -0.911  -0.902  -0.801
382   H         0.589   0.576   0.542   0.667   0.642   0.524   0.424   0.399   0.313
383   Q        -0.913  -0.907  -0.832  -0.992  -0.995  -0.867  -0.911  -0.902  -0.801
384   R        -0.281  -0.252  -0.251  -0.215  -0.174  -0.169  -0.466  -0.424  -0.423
385   L        -0.913  -0.907  -0.832  -0.966  -0.969  -0.842  -0.911  -0.902  -0.801
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   N         0.589   0.576   0.542   0.643   0.619   0.554   0.424   0.399   0.313
392   F        -0.913  -0.907  -0.832  -0.761  -0.755  -0.639  -0.911  -0.902  -0.801
393   T        -1.319  -1.314  -1.235  -1.333  -1.309  -1.203  -1.089  -1.080  -0.978
394   R        -0.230  -0.209  -0.236  -0.146  -0.124  -0.153  -0.417  -0.387  -0.412
395   R        -0.651  -0.707  -0.758  -0.798  -0.862  -0.870  -0.615  -0.679  -0.721
396   G        -0.230  -0.242  -0.247   0.024  -0.001  -0.002  -0.417  -0.432  -0.427
397   W        -0.809  -0.839  -0.796  -0.625  -0.674  -0.610  -0.812  -0.836  -0.766
398   S        -1.230  -1.239  -1.203  -1.290  -1.281  -1.186  -1.010  -1.015  -0.951
399   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
400   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
401   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
402   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
403   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
404   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
405   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
406   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
407   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
408   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
409   S        -1.230  -1.224  -1.203  -1.367  -1.356  -1.268  -1.010  -1.002  -0.950
410   F        -0.651  -0.626  -0.708  -0.510  -0.461  -0.609  -0.615  -0.583  -0.665
411   F        -1.230  -1.224  -1.203  -0.940  -0.937  -0.917  -1.010  -1.002  -0.950
412   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
413   Q        -1.651  -1.642  -1.565  -1.289  -1.284  -1.160  -1.208  -1.196  -1.095
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12477
Output conservation file - output/Q12477
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
