1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    M         1.468   1.497   1.630   1.686   1.721   1.908   1.568   1.632   1.837
30    P        -0.655  -0.599  -0.532  -0.804  -0.684  -0.587  -0.833  -0.744  -0.639
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    L        -1.489  -1.352  -1.240  -1.699  -1.534  -1.396  -1.260  -1.145  -0.992
38    K        -1.297  -1.122  -0.962  -1.400  -1.164  -0.920  -1.260  -1.099  -0.891
39    N        -1.605  -1.405  -1.261  -1.620  -1.361  -1.167  -1.373  -1.202  -1.010
40    S        -1.297  -1.159  -0.966  -1.366  -1.173  -0.889  -1.260  -1.128  -0.893
41    S        -0.893  -1.008  -0.921  -0.831  -1.033  -0.900  -0.870  -1.002  -0.857
42    A        -1.916  -1.703  -1.506  -2.044  -1.743  -1.490  -1.497  -1.328  -1.091
43    T        -1.666  -1.688  -1.500  -1.390  -1.450  -1.184  -1.313  -1.319  -1.087
44    L        -0.005  -0.005  -0.041  -0.037  -0.082  -0.160  -0.242  -0.273  -0.302
45    K        -0.085  -0.063  -0.052  -0.334  -0.323  -0.259  -0.390  -0.380  -0.322
46    L        -0.005   0.301   0.122  -0.171   0.280   0.079  -0.242   0.255  -0.030
47    N         0.129  -0.064  -0.410   0.410   0.177  -0.305   0.238  -0.024  -0.479
48    T        -0.005  -0.056  -0.052  -0.085  -0.172  -0.162  -0.242  -0.339  -0.319
49    G         1.468   1.497   1.630   1.408   1.473   1.657   1.568   1.632   1.837
50    A        -1.314  -1.306  -1.211  -1.304  -1.235  -1.058  -1.165  -1.121  -0.968
51    S        -1.073  -0.990  -0.908  -1.249  -1.116  -0.989  -1.091  -0.982  -0.842
52    I         1.468   1.497   1.630   1.426   1.464   1.673   1.568   1.632   1.837
53    P         1.468   1.497   1.630   1.462   1.505   1.706   1.568   1.632   1.837
54    V        -0.687  -0.831  -0.874  -0.544  -0.773  -0.822  -0.648  -0.813  -0.811
55    L        -0.609  -0.584  -0.547  -0.838  -0.862  -0.799  -0.759  -0.753  -0.662
56    G         1.468   1.497   1.630   1.408   1.473   1.657   1.568   1.632   1.837
57    F         0.741   0.731   0.628   0.583   0.586   0.433   0.681   0.645   0.378
58    G         1.468   1.497   1.630   1.408   1.473   1.657   1.568   1.632   1.837
59    T         1.468   1.497   1.630   1.423   1.473   1.670   1.568   1.632   1.837
60    W         1.468   1.497   1.630   1.670   1.698   1.893   1.568   1.632   1.837
61    R        -1.015  -1.011  -0.922  -0.996  -0.956  -0.797  -1.017  -1.021  -0.858
62    S         0.565   0.484   0.118   0.731   0.638   0.137   0.644   0.525  -0.035
63    V        -1.674  -1.794  -1.712  -1.412  -1.683  -1.617  -1.202  -1.306  -1.146
64    D        -1.841  -1.884  -1.719  -1.612  -1.732  -1.494  -1.350  -1.369  -1.151
65    N        -0.753  -0.925  -0.909  -0.650  -0.924  -0.915  -0.685  -0.902  -0.845
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    N        -0.433  -0.502  -0.543  -0.368  -0.482  -0.532  -0.488  -0.617  -0.651
68    G        -0.584  -0.643  -0.575  -0.682  -0.820  -0.713  -0.702  -0.810  -0.689
69    Y        -0.435  -0.265  -0.078  -0.659  -0.427  -0.158  -0.788  -0.585  -0.350
70    H        -1.226  -1.220  -1.179  -1.122  -1.019  -0.949  -1.088  -1.040  -0.938
71    S         1.011   1.019   0.764   1.104   1.099   0.795   1.087   1.103   0.640
72    V         1.011   1.002   0.769   1.046   1.057   0.781   1.087   1.079   0.650
73    I        -1.424  -1.437  -1.243  -1.560  -1.591  -1.298  -1.239  -1.231  -0.998
74    A        -0.756  -0.560  -0.492  -0.750  -0.562  -0.454  -0.944  -0.719  -0.600
75    A         1.468   1.497   1.630   1.462   1.484   1.706   1.568   1.632   1.837
76    L         1.468   1.497   1.630   1.241   1.301   1.506   1.568   1.632   1.837
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    K        -0.292  -0.033  -0.012  -0.592  -0.140  -0.106  -0.611  -0.226  -0.243
79    A        -1.841  -1.907  -1.718  -1.645  -1.790  -1.544  -1.350  -1.381  -1.150
80    G         1.468   1.497   1.630   1.408   1.473   1.657   1.568   1.632   1.837
81    Y         1.468   1.497   1.630   1.595   1.621   1.826   1.568   1.632   1.837
82    R         0.741   0.739   0.620   0.895   0.869   0.620   0.681   0.659   0.360
83    H         1.011   0.936   0.751   1.269   1.171   0.879   1.087   0.981   0.616
84    I         1.468   1.497   1.630   1.426   1.464   1.673   1.568   1.632   1.837
85    D         1.468   1.497   1.630   1.498   1.545   1.738   1.568   1.632   1.837
86    A         0.546   0.519   0.544   0.454   0.386   0.372   0.349   0.258   0.205
87    A         1.468   1.497   1.630   1.462   1.484   1.706   1.568   1.632   1.837
88    A        -0.831  -0.775  -0.814  -0.684  -0.553  -0.580  -0.870  -0.731  -0.737
89    I        -0.655  -0.495  -0.493  -0.690  -0.392  -0.339  -0.833  -0.606  -0.590
90    Y         1.468   1.497   1.630   1.595   1.621   1.826   1.568   1.632   1.837
91    L        -0.467  -0.221  -0.388  -0.535  -0.120  -0.409  -0.648  -0.262  -0.450
92    N         1.468   1.497   1.630   1.467   1.512   1.710   1.568   1.632   1.837
93    E         1.468   1.497   1.630   1.382   1.432   1.634   1.568   1.632   1.837
94    E        -0.488  -0.449  -0.488  -0.623  -0.522  -0.568  -0.685  -0.585  -0.588
95    E        -0.893  -0.982  -0.921  -0.774  -0.948  -0.810  -0.870  -0.979  -0.855
96    V         0.741   0.664   0.593   0.704   0.592   0.425   0.681   0.528   0.305
97    G         1.468   1.497   1.630   1.408   1.473   1.657   1.568   1.632   1.837
98    R        -1.599  -1.664  -1.489  -1.616  -1.653  -1.337  -1.276  -1.299  -1.079
99    A         0.407   0.423   0.526   0.202   0.210   0.326   0.090   0.070   0.168
100   I         1.011   0.936   0.751   1.052   0.964   0.687   1.087   0.981   0.616
101   K         0.407   0.399   0.512   0.196   0.160   0.335   0.090   0.022   0.139
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   D         0.257   0.330   0.507  -0.082   0.041   0.303  -0.205  -0.119   0.127
106   S        -0.467  -0.292  -0.425  -0.592  -0.201  -0.367  -0.648  -0.345  -0.498
107   G         1.468   1.497   1.630   1.408   1.473   1.657   1.568   1.632   1.837
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   V         0.741   0.720   0.615   0.704   0.676   0.469   0.681   0.626   0.352
110   P         0.239   0.376   0.530  -0.163   0.093   0.312  -0.242  -0.024   0.176
111   R         1.468   1.497   1.630   1.598   1.627   1.828   1.568   1.632   1.837
112   E         0.565   0.397   0.097   0.655   0.464   0.014   0.644   0.407  -0.068
113   E         0.312   0.357   0.510   0.067   0.109   0.313  -0.094  -0.064   0.134
114   I         0.305   0.213   0.043   0.344   0.212  -0.092   0.275   0.131  -0.154
115   F         0.741   0.638   0.624   0.953   0.801   0.751   0.681   0.481   0.369
116   I         0.546   0.540   0.554   0.414   0.389   0.351   0.349   0.299   0.227
117   T         1.011   0.936   0.751   1.060   0.990   0.724   1.087   0.981   0.616
118   T         0.741   0.638   0.624   0.738   0.586   0.519   0.681   0.481   0.369
119   K         1.468   1.497   1.630   1.345   1.388   1.600   1.568   1.632   1.837
120   L        -0.292  -0.035  -0.002  -0.714  -0.276  -0.268  -0.611  -0.228  -0.228
121   W         1.468   1.497   1.630   1.670   1.698   1.893   1.568   1.632   1.837
122   G        -1.182  -1.147  -0.939  -1.237  -1.127  -0.849  -1.165  -1.122  -0.871
123   T         0.122   0.059  -0.033   0.110  -0.019  -0.140  -0.020  -0.171  -0.285
124   E        -1.081  -1.087  -0.961  -0.904  -0.996  -0.813  -1.054  -1.076  -0.890
125   Q         0.122   0.052  -0.028   0.367   0.251   0.105  -0.020  -0.135  -0.274
126   R        -1.314  -1.295  -1.202  -1.174  -1.129  -1.026  -1.165  -1.112  -0.960
127   D        -0.893  -0.994  -0.925  -0.673  -0.860  -0.789  -0.870  -0.978  -0.858
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   P        -0.290  -0.355  -0.488  -0.266  -0.363  -0.553  -0.353  -0.455  -0.588
131   E         0.305   0.175   0.014   0.346   0.154  -0.083   0.275   0.050  -0.202
132   A        -1.135  -1.272  -1.222  -0.992  -1.238  -1.185  -0.944  -1.084  -0.981
133   A        -0.085   0.151   0.081  -0.238   0.188   0.087  -0.390   0.031  -0.093
134   L         1.468   1.497   1.630   1.241   1.301   1.506   1.568   1.632   1.837
135   N        -0.471  -0.278  -0.143  -0.790  -0.501  -0.322  -0.833  -0.595  -0.433
136   K        -1.257  -0.966  -0.907  -1.474  -1.084  -1.019  -1.239  -0.954  -0.843
137   S         0.741   0.638   0.624   0.760   0.599   0.532   0.681   0.481   0.369
138   L         1.468   1.497   1.630   1.241   1.301   1.506   1.568   1.632   1.837
139   K        -0.730  -0.713  -0.563  -0.901  -0.853  -0.587  -0.907  -0.884  -0.680
140   R        -0.512  -0.643  -0.564  -0.391  -0.651  -0.570  -0.611  -0.793  -0.677
141   L         1.468   1.497   1.630   1.241   1.301   1.506   1.568   1.632   1.837
142   G         0.565   0.397   0.097   0.684   0.511   0.049   0.644   0.407  -0.068
143   L         1.468   1.497   1.630   1.241   1.301   1.506   1.568   1.632   1.837
144   D         0.305   0.192   0.004   0.448   0.261  -0.048   0.275   0.064  -0.225
145   Y         1.468   1.497   1.630   1.595   1.621   1.826   1.568   1.632   1.837
146   V         0.565   0.397   0.097   0.657   0.466  -0.005   0.644   0.407  -0.068
147   D         1.468   1.497   1.630   1.498   1.545   1.738   1.568   1.632   1.837
148   L        -0.467  -0.343  -0.431  -0.587  -0.382  -0.514  -0.648  -0.404  -0.506
149   Y        -0.292  -0.072  -0.020  -0.470  -0.016   0.024  -0.611  -0.283  -0.255
150   L         1.468   1.497   1.630   1.241   1.301   1.506   1.568   1.632   1.837
151   M         0.056  -0.021  -0.081   0.107  -0.027  -0.144  -0.057  -0.206  -0.341
152   H         1.468   1.497   1.630   1.642   1.671   1.868   1.568   1.632   1.837
153   W         1.468   1.497   1.630   1.670   1.698   1.893   1.568   1.632   1.837
154   P         1.468   1.497   1.630   1.462   1.505   1.706   1.568   1.632   1.837
155   V         0.129  -0.057  -0.386   0.315   0.095  -0.387   0.238  -0.015  -0.447
156   P        -0.290  -0.468  -0.505  -0.222  -0.503  -0.593  -0.353  -0.589  -0.611
157   L        -0.120  -0.272  -0.444  -0.117  -0.283  -0.490  -0.094  -0.304  -0.525
158   K        -0.512  -0.608  -0.540  -0.542  -0.739  -0.692  -0.611  -0.750  -0.652
159   T        -0.753  -0.855  -0.895  -0.617  -0.816  -0.911  -0.685  -0.826  -0.828
160   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   D        -0.940  -1.036  -0.955  -0.863  -1.070  -0.978  -0.895  -1.022  -0.885
165   G         0.627   0.587   0.596   0.546   0.494   0.437   0.491   0.388   0.313
166   N         0.305   0.179   0.020   0.411   0.217  -0.056   0.275   0.054  -0.192
167   V        -1.674  -1.769  -1.715  -1.308  -1.538  -1.514  -1.202  -1.286  -1.148
168   L        -0.512  -0.640  -0.571  -0.567  -0.799  -0.747  -0.611  -0.785  -0.686
169   C        -1.544  -1.673  -1.506  -1.387  -1.629  -1.389  -1.197  -1.304  -1.089
170   I        -0.530  -0.555  -0.516  -0.426  -0.482  -0.444  -0.694  -0.712  -0.620
171   P         1.468   1.497   1.630   1.455   1.495   1.700   1.568   1.632   1.837
172   T        -0.852  -0.820  -0.592  -1.181  -1.088  -0.737  -0.996  -0.977  -0.708
173   L        -0.956  -1.020  -0.922  -0.914  -1.098  -0.976  -0.945  -0.997  -0.849
174   E        -0.530  -0.499  -0.506  -0.655  -0.607  -0.612  -0.694  -0.650  -0.617
175   D        -0.016  -0.260  -0.447   0.238  -0.088  -0.432   0.060  -0.276  -0.525
176   G         0.959   0.934   0.731   0.972   0.970   0.671   1.015   0.977   0.579
177   T        -1.135  -1.146  -0.953  -1.208  -1.304  -1.028  -1.096  -1.122  -0.883
178   V        -0.721  -0.834  -0.920  -0.481  -0.757  -0.937  -0.644  -0.815  -0.850
179   D         0.891   0.818   0.663   1.009   0.925   0.704   0.916   0.793   0.446
180   I         1.468   1.497   1.630   1.424   1.460   1.671   1.568   1.632   1.837
181   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   T        -1.314  -1.243  -1.213  -1.185  -1.074  -1.092  -1.165  -1.071  -0.971
183   K        -0.707  -0.844  -1.140  -0.380  -0.557  -0.981  -0.463  -0.633  -0.902
184   E        -0.655  -0.462  -0.466  -0.780  -0.417  -0.485  -0.833  -0.552  -0.554
185   W        -1.314  -1.315  -1.207  -1.101  -1.027  -0.883  -1.165  -1.135  -0.968
186   N        -0.718  -0.746  -0.603  -0.760  -0.848  -0.659  -0.833  -0.897  -0.717
187   F        -1.139  -1.100  -0.926  -0.918  -0.901  -0.652  -1.128  -1.075  -0.856
188   I        -1.182  -1.119  -0.945  -1.327  -1.283  -1.033  -1.165  -1.103  -0.876
189   K        -0.356  -0.521  -0.527  -0.341  -0.599  -0.599  -0.390  -0.628  -0.629
190   T         1.011   0.936   0.751   1.062   0.992   0.733   1.087   0.981   0.616
191   W         0.546   0.545   0.570   0.729   0.690   0.679   0.349   0.307   0.260
192   E        -0.687  -0.779  -0.867  -0.636  -0.766  -0.831  -0.648  -0.764  -0.802
193   L        -1.599  -1.591  -1.484  -1.433  -1.575  -1.460  -1.276  -1.257  -1.074
194   M         0.741   0.740   0.671   0.967   0.949   0.766   0.681   0.661   0.463
195   Q         0.257   0.330   0.504   0.004   0.119   0.388  -0.205  -0.120   0.121
196   E        -0.998  -0.858  -0.868  -1.107  -0.909  -0.881  -1.017  -0.844  -0.801
197   L        -0.125   0.065   0.007  -0.546  -0.188  -0.258  -0.463  -0.145  -0.219
198   P        -0.512  -0.571  -0.544  -0.675  -0.753  -0.703  -0.611  -0.701  -0.653
199   K        -0.120  -0.319  -0.486  -0.062  -0.359  -0.610  -0.094  -0.386  -0.579
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   T         0.122   0.084  -0.025   0.083   0.012  -0.196  -0.020  -0.108  -0.275
202   G         0.565   0.547   0.130   0.680   0.687   0.092   0.644   0.613  -0.018
203   K         1.011   0.936   0.751   0.998   0.926   0.711   1.087   0.981   0.616
204   T         0.056  -0.047  -0.049   0.051  -0.130  -0.194  -0.057  -0.248  -0.293
205   K         0.407   0.384   0.511   0.196   0.135   0.334   0.090  -0.009   0.136
206   A        -0.467  -0.525  -0.506  -0.504  -0.551  -0.445  -0.648  -0.689  -0.615
207   V         0.741   0.731   0.628   0.732   0.707   0.509   0.681   0.645   0.378
208   G         1.468   1.497   1.630   1.408   1.473   1.657   1.568   1.632   1.837
209   V         0.565   0.397   0.097   0.657   0.466  -0.005   0.644   0.407  -0.068
210   S         1.468   1.497   1.630   1.450   1.491   1.695   1.568   1.632   1.837
211   N         1.468   1.497   1.630   1.467   1.512   1.710   1.568   1.632   1.837
212   F         1.011   0.936   0.751   1.256   1.175   0.934   1.087   0.981   0.616
213   S         0.056  -0.047  -0.049   0.092  -0.090  -0.144  -0.057  -0.248  -0.293
214   I        -0.687  -0.855  -0.892  -0.613  -0.891  -0.941  -0.648  -0.848  -0.828
215   N        -1.599  -1.645  -1.484  -1.496  -1.605  -1.371  -1.276  -1.289  -1.075
216   N        -0.467  -0.427  -0.490  -0.411  -0.379  -0.412  -0.648  -0.604  -0.600
217   I         0.741   0.766   0.639   0.551   0.598   0.382   0.681   0.706   0.399
218   K        -0.120  -0.068  -0.437  -0.008   0.004  -0.456  -0.094  -0.092  -0.521
219   E        -0.784  -0.784  -0.885  -0.727  -0.719  -0.822  -0.796  -0.811  -0.823
220   L         0.565   0.397   0.097   0.516   0.337  -0.095   0.644   0.407  -0.068
221   L         1.468   1.497   1.630   1.241   1.301   1.506   1.568   1.632   1.837
222   E        -1.135  -1.203  -1.224  -1.043  -1.185  -1.213  -0.944  -1.030  -0.981
223   S        -1.357  -1.389  -1.208  -1.363  -1.381  -1.097  -1.202  -1.197  -0.970
224   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   N        -0.753  -0.787  -0.890  -0.589  -0.685  -0.854  -0.685  -0.747  -0.820
227   K        -1.456  -1.232  -1.198  -1.558  -1.207  -1.157  -1.276  -1.051  -0.959
228   V         0.305   0.239   0.007   0.330   0.237  -0.167   0.275   0.156  -0.217
229   V         0.546   0.477   0.535   0.392   0.247   0.270   0.349   0.177   0.187
230   P         1.468   1.497   1.630   1.462   1.505   1.706   1.568   1.632   1.837
231   A         0.565   0.438   0.109   0.739   0.572   0.117   0.644   0.462  -0.050
232   T         0.129   0.037  -0.377   0.315   0.207  -0.374   0.238   0.102  -0.436
233   N         0.741   0.638   0.624   0.814   0.671   0.630   0.681   0.481   0.369
234   Q         1.468   1.497   1.630   1.634   1.657   1.860   1.568   1.632   1.837
235   I        -0.609  -0.648  -0.555  -0.673  -0.711  -0.533  -0.759  -0.822  -0.669
236   E         1.468   1.497   1.630   1.382   1.432   1.634   1.568   1.632   1.837
237   I        -0.512  -0.571  -0.544  -0.714  -0.804  -0.753  -0.611  -0.701  -0.653
238   H         1.468   1.497   1.630   1.642   1.671   1.868   1.568   1.632   1.837
239   P         1.468   1.497   1.630   1.462   1.505   1.706   1.568   1.632   1.837
240   L        -0.512  -0.625  -0.567  -0.584  -0.714  -0.564  -0.611  -0.777  -0.683
241   L         1.468   1.497   1.630   1.241   1.301   1.506   1.568   1.632   1.837
242   P         1.011   1.029   0.768   1.102   1.130   0.795   1.087   1.118   0.648
243   Q         1.468   1.497   1.630   1.634   1.657   1.860   1.568   1.632   1.837
244   D        -1.314  -1.258  -1.203  -1.383  -1.179  -1.046  -1.165  -1.082  -0.961
245   E         1.011   1.000   0.758   1.016   1.016   0.688   1.087   1.076   0.630
246   L         0.129  -0.121  -0.419   0.191  -0.084  -0.471   0.238  -0.094  -0.490
247   I        -1.248  -1.201  -0.964  -1.186  -1.271  -0.982  -1.202  -1.161  -0.892
248   A        -0.687  -0.744  -0.868  -0.574  -0.663  -0.791  -0.648  -0.736  -0.807
249   F        -0.227  -0.267  -0.122  -0.198  -0.321  -0.136  -0.500  -0.587  -0.406
250   C        -0.356  -0.472  -0.521   0.014  -0.211  -0.351  -0.390  -0.577  -0.622
251   K         1.468   1.497   1.630   1.345   1.388   1.600   1.568   1.632   1.837
252   E        -0.292  -0.225  -0.112  -0.638  -0.546  -0.367  -0.611  -0.547  -0.393
253   K        -0.655  -0.420  -0.529  -0.888  -0.623  -0.671  -0.833  -0.591  -0.634
254   G        -0.467  -0.308  -0.419  -0.550  -0.191  -0.344  -0.648  -0.363  -0.490
255   I         1.468   1.497   1.630   1.426   1.464   1.673   1.568   1.632   1.837
256   V        -1.015  -0.831  -0.856  -1.052  -0.772  -0.822  -1.017  -0.843  -0.795
257   V        -0.897  -0.760  -0.569  -1.052  -0.957  -0.723  -1.054  -0.911  -0.682
258   E        -0.488  -0.495  -0.498  -0.638  -0.551  -0.520  -0.685  -0.632  -0.599
259   A         1.011   1.000   0.758   1.104   1.078   0.786   1.087   1.076   0.630
260   Y         0.312   0.672   0.726   0.261   0.818   0.891  -0.094   0.542   0.570
261   S         1.011   0.998   0.760   1.113   1.109   0.851   1.087   1.073   0.634
262   P         1.468   1.497   1.630   1.462   1.505   1.706   1.568   1.632   1.837
263   F         0.257   0.332   0.506  -0.055   0.007   0.263  -0.205  -0.116   0.125
264   G         1.011   0.918   0.756   1.050   0.971   0.738   1.087   0.952   0.627
265   S         0.305   0.179   0.020   0.411   0.217  -0.026   0.275   0.054  -0.192
266   A        -1.182  -1.110  -0.932  -1.268  -1.150  -0.882  -1.165  -1.097  -0.865
267   N        -0.730  -0.670  -0.561  -0.905  -0.801  -0.630  -0.907  -0.846  -0.676
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   A        -0.467  -0.259  -0.403  -0.575  -0.159  -0.362  -0.648  -0.306  -0.470
276   P        -0.120  -0.226  -0.464   0.047  -0.149  -0.501  -0.094  -0.280  -0.553
277   L         0.129   0.035  -0.394   0.180   0.088  -0.470   0.238   0.102  -0.458
278   L        -0.290  -0.415  -0.503  -0.413  -0.603  -0.668  -0.353  -0.551  -0.611
279   K        -0.512  -0.585  -0.556  -0.629  -0.801  -0.732  -0.611  -0.752  -0.670
280   E        -0.893  -0.996  -0.933  -0.757  -0.917  -0.829  -0.870  -0.994  -0.866
281   Q        -0.356  -0.429  -0.511  -0.320  -0.462  -0.586  -0.390  -0.522  -0.613
282   A        -0.831  -0.700  -0.827  -1.006  -0.648  -0.847  -0.870  -0.653  -0.750
283   I        -0.125  -0.108  -0.048  -0.421  -0.356  -0.270  -0.463  -0.412  -0.311
284   I        -1.314  -1.201  -1.168  -1.442  -1.180  -1.130  -1.165  -1.028  -0.933
285   D        -0.753  -0.654  -0.870  -0.713  -0.665  -0.930  -0.685  -0.657  -0.806
286   M        -0.085   0.225   0.096  -0.362   0.233   0.093  -0.390   0.125  -0.071
287   A         1.468   1.497   1.630   1.462   1.484   1.706   1.568   1.632   1.837
288   K        -0.893  -0.971  -0.917  -0.844  -1.026  -0.966  -0.870  -0.972  -0.854
289   K         0.565   0.397   0.097   0.629   0.434   0.023   0.644   0.407  -0.068
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   H        -0.718  -0.784  -0.614  -0.616  -0.794  -0.563  -0.833  -0.937  -0.729
293   G        -1.081  -0.656  -0.865  -1.170  -0.506  -0.855  -1.054  -0.592  -0.799
294   V        -0.467  -0.265  -0.405  -0.620  -0.221  -0.420  -0.648  -0.317  -0.473
295   E        -1.182  -1.124  -0.951  -1.344  -1.302  -1.047  -1.165  -1.108  -0.883
296   P         1.011   0.957   0.759   1.101   1.048   0.777   1.087   1.012   0.632
297   A        -0.085   0.151   0.081  -0.269   0.178   0.073  -0.390   0.031  -0.093
298   Q        -0.940  -0.819  -0.582  -1.106  -0.924  -0.596  -1.091  -0.978  -0.698
299   L        -0.005  -0.014  -0.043  -0.163  -0.221  -0.264  -0.242  -0.300  -0.307
300   I         0.305   0.194   0.013   0.200   0.039  -0.213   0.275   0.072  -0.203
301   I        -0.655  -0.519  -0.479  -0.867  -0.604  -0.606  -0.833  -0.624  -0.574
302   S         1.011   0.998   0.760   1.093   1.086   0.783   1.087   1.073   0.634
303   W         0.257   0.474   0.588   0.210   0.568   0.712  -0.205   0.171   0.295
304   S        -0.655  -0.554  -0.538  -0.639  -0.542  -0.510  -0.833  -0.709  -0.645
305   I        -0.356  -0.459  -0.527  -0.334  -0.564  -0.704  -0.390  -0.572  -0.633
306   Q        -1.599  -1.660  -1.496  -1.357  -1.406  -1.173  -1.276  -1.296  -1.083
307   R         0.312   0.672   0.726   0.198   0.795   0.856  -0.094   0.542   0.570
308   G         0.741   0.740   0.671   0.705   0.718   0.557   0.681   0.661   0.463
309   Y         0.122   0.052  -0.028   0.147   0.056  -0.070  -0.020  -0.135  -0.274
310   V        -0.120  -0.321  -0.478   0.025  -0.253  -0.456  -0.094  -0.388  -0.569
311   V         1.468   1.497   1.630   1.392   1.445   1.643   1.568   1.632   1.837
312   L         0.257   0.482   0.582  -0.245   0.148   0.280  -0.205   0.187   0.284
313   A         1.011   1.019   0.764   1.105   1.119   0.798   1.087   1.103   0.640
314   K         1.468   1.497   1.630   1.345   1.388   1.600   1.568   1.632   1.837
315   S         1.468   1.497   1.630   1.450   1.491   1.695   1.568   1.632   1.837
316   V         0.565   0.454   0.107   0.687   0.576   0.112   0.644   0.486  -0.053
317   N        -0.085  -0.066  -0.048  -0.268  -0.237  -0.170  -0.390  -0.384  -0.315
318   P        -0.788  -0.633  -0.531  -1.008  -0.786  -0.614  -0.980  -0.805  -0.643
319   E        -0.753  -0.855  -0.909  -0.543  -0.726  -0.780  -0.685  -0.828  -0.844
320   R         1.468   1.497   1.630   1.598   1.627   1.828   1.568   1.632   1.837
321   I         0.565   0.547   0.130   0.688   0.665   0.074   0.644   0.613  -0.018
322   V        -1.139  -1.090  -0.929  -1.321  -1.282  -1.048  -1.128  -1.073  -0.862
323   S        -0.467  -0.250  -0.411  -0.595  -0.167  -0.394  -0.648  -0.298  -0.480
324   N         1.468   1.497   1.630   1.467   1.512   1.710   1.568   1.632   1.837
325   F        -1.073  -0.988  -0.888  -1.201  -1.014  -0.905  -1.091  -0.980  -0.823
326   K         0.129  -0.027  -0.390   0.250   0.052  -0.487   0.238   0.023  -0.453
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   I        -1.666  -1.668  -1.510  -1.558  -1.643  -1.443  -1.313  -1.308  -1.093
329   F        -0.730  -0.629  -0.559  -0.911  -0.764  -0.657  -0.907  -0.809  -0.674
330   T        -1.490  -1.370  -1.237  -1.445  -1.326  -1.120  -1.276  -1.188  -0.993
331   L         1.468   1.497   1.630   1.241   1.301   1.506   1.568   1.632   1.837
332   P        -0.893  -0.863  -0.904  -0.830  -0.878  -0.875  -0.870  -0.899  -0.840
333   E        -2.025  -1.875  -1.708  -1.808  -1.670  -1.435  -1.497  -1.365  -1.146
334   D         0.129  -0.009  -0.390   0.304   0.136  -0.404   0.238   0.046  -0.453
335   D         1.011   0.918   0.756   1.135   1.036   0.797   1.087   0.952   0.627
336   F        -1.257  -1.340  -1.239  -1.180  -1.192  -1.037  -1.091  -1.166  -0.994
337   K        -0.797  -0.599  -0.547  -0.998  -0.791  -0.652  -0.944  -0.775  -0.663
338   T        -1.599  -1.497  -1.480  -1.515  -1.484  -1.426  -1.276  -1.207  -1.074
339   I         0.312   0.338   0.503  -0.145  -0.112   0.149  -0.094  -0.104   0.120
340   S         0.129   0.064  -0.381   0.396   0.324  -0.300   0.238   0.142  -0.441
341   N        -0.609  -0.654  -0.573  -0.697  -0.796  -0.680  -0.759  -0.820  -0.689
342   L         0.305   0.121   0.001   0.210  -0.032  -0.195   0.275  -0.019  -0.221
343   S        -0.655  -0.587  -0.545  -0.650  -0.603  -0.539  -0.833  -0.754  -0.653
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   K        -0.402  -0.509  -0.511  -0.561  -0.710  -0.697  -0.537  -0.662  -0.622
349   V        -1.499  -1.601  -1.495  -1.372  -1.607  -1.489  -1.165  -1.256  -1.083
350   H        -1.350  -1.553  -1.506  -1.060  -1.389  -1.375  -0.996  -1.197  -1.089
351   G         0.959   0.843   0.694   0.978   0.860   0.597   1.015   0.833   0.507
352   T        -0.439  -0.499  -0.538  -0.466  -0.613  -0.651  -0.543  -0.657  -0.650
353   K        -1.599  -1.630  -1.489  -1.277  -1.400  -1.210  -1.276  -1.280  -1.079
354   R         1.468   1.497   1.630   1.598   1.627   1.828   1.568   1.632   1.837
355   V        -1.257  -1.301  -1.234  -1.109  -1.177  -1.108  -1.091  -1.140  -0.990
356   V        -0.831  -0.801  -0.869  -0.838  -0.763  -0.789  -0.870  -0.810  -0.803
357   D        -1.841  -1.886  -1.724  -1.577  -1.614  -1.366  -1.350  -1.370  -1.153
358   M         0.129  -0.048  -0.404   0.408   0.196  -0.289   0.238  -0.003  -0.471
359   K        -1.033  -1.220  -1.207  -0.867  -1.156  -1.152  -0.831  -1.029  -0.965
360   W         0.239   0.395   0.537   0.172   0.408   0.601  -0.242   0.014   0.192
361   G        -1.135  -1.225  -1.217  -0.998  -1.182  -1.203  -0.944  -1.057  -0.978
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   S        -0.730  -0.667  -0.559  -0.908  -0.809  -0.635  -0.907  -0.849  -0.673
366   F        -0.295  -0.509  -0.813   0.165  -0.128  -0.626  -0.131  -0.402  -0.735
367   P        -0.295  -0.331  -0.775   0.051   0.001  -0.601  -0.131  -0.193  -0.694
368   I        -0.940  -1.057  -0.951  -0.854  -1.071  -0.973  -0.895  -1.035  -0.882
369   F         0.959   0.856   0.720   1.176   1.043   0.816   1.015   0.855   0.557
370   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
376   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -0.436  -0.783  -0.623  -0.126  -0.692  -0.488  -0.468  -0.934  -0.738
382   Q        -1.599  -1.654  -1.493  -1.213  -1.400  -1.200  -1.276  -1.293  -1.080
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12458
Output conservation file - output/Q12458
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
