1     M         1.629   1.646   1.767   1.844   1.867   2.053   1.792   1.818   2.019
2     V         0.938   0.866   0.750   0.886   0.787   0.609   0.976   0.859   0.619
3     V        -0.022  -0.112  -0.105  -0.129  -0.266  -0.262  -0.189  -0.315  -0.313
4     N        -0.022  -0.051  -0.090   0.183   0.154   0.052  -0.189  -0.215  -0.291
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     N         1.629   1.646   1.767   1.639   1.665   1.849   1.792   1.818   2.019
8     P         1.629   1.646   1.767   1.687   1.707   1.897   1.792   1.818   2.019
9     N         1.629   1.646   1.767   1.639   1.665   1.849   1.792   1.818   2.019
10    N         1.629   1.646   1.767   1.639   1.665   1.849   1.792   1.818   2.019
11    W         1.629   1.646   1.767   1.789   1.812   1.998   1.792   1.818   2.019
12    H         1.629   1.646   1.767   1.798   1.821   2.007   1.792   1.818   2.019
13    W         1.629   1.646   1.767   1.789   1.812   1.998   1.792   1.818   2.019
14    V         0.938   0.866   0.750   0.909   0.813   0.659   0.976   0.859   0.619
15    D         0.280   0.149   0.000   0.411   0.232  -0.010   0.277   0.089  -0.145
16    K         1.629   1.646   1.767   1.503   1.531   1.715   1.792   1.818   2.019
17    N         0.597   0.528   0.575   0.575   0.455   0.495   0.393   0.255   0.278
18    C         0.938   0.881   0.758   1.273   1.203   1.028   0.976   0.882   0.634
19    I        -0.596  -0.688  -0.645  -0.529  -0.648  -0.604  -0.656  -0.752  -0.683
20    G        -1.112  -1.164  -1.080  -1.060  -1.158  -1.033  -1.005  -1.047  -0.916
21    W         1.629   1.646   1.767   1.789   1.812   1.998   1.792   1.818   2.019
22    A        -0.278  -0.262  -0.190  -0.479  -0.464  -0.394  -0.539  -0.517  -0.429
23    K        -0.674  -0.690  -0.647  -0.636  -0.643  -0.565  -0.772  -0.782  -0.689
24    E        -0.674  -0.600  -0.636  -0.709  -0.616  -0.645  -0.772  -0.697  -0.679
25    Y         0.938   0.881   0.758   1.207   1.142   0.995   0.976   0.882   0.634
26    F         1.629   1.646   1.767   1.637   1.660   1.848   1.792   1.818   2.019
27    K        -0.794  -0.813  -0.698  -0.826  -0.844  -0.703  -0.889  -0.898  -0.744
28    Q        -0.596  -0.637  -0.637  -0.615  -0.681  -0.671  -0.656  -0.703  -0.674
29    K        -0.022  -0.085  -0.099  -0.105  -0.184  -0.229  -0.189  -0.270  -0.307
30    L         1.629   1.646   1.767   1.533   1.561   1.745   1.792   1.818   2.019
31    V        -0.794  -0.815  -0.702  -0.864  -0.888  -0.715  -0.889  -0.901  -0.747
32    G        -0.278  -0.279  -0.188  -0.427  -0.444  -0.323  -0.539  -0.545  -0.426
33    V        -0.022   0.003  -0.089  -0.088  -0.052  -0.203  -0.189  -0.160  -0.291
34    E        -1.430  -1.378  -1.397  -1.336  -1.245  -1.318  -1.122  -1.070  -1.034
35    A         0.280   0.390   0.047   0.421   0.558   0.079   0.277   0.433  -0.076
36    G        -1.550  -1.569  -1.444  -1.480  -1.528  -1.341  -1.238  -1.244  -1.075
37    S        -0.022   0.031  -0.075  -0.168  -0.088  -0.269  -0.189  -0.114  -0.269
38    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    D         0.597   0.672   0.623   0.524   0.636   0.536   0.393   0.523   0.373
41    K        -1.112  -1.127  -1.074  -1.085  -1.101  -1.022  -1.005  -1.018  -0.911
42    K        -1.550  -1.530  -1.437  -1.441  -1.408  -1.256  -1.238  -1.215  -1.070
43    Y        -1.868  -1.877  -1.741  -1.550  -1.596  -1.416  -1.355  -1.354  -1.178
44    A        -0.022   0.024  -0.068  -0.052   0.027  -0.139  -0.189  -0.110  -0.254
45    K        -1.430  -1.378  -1.397  -1.243  -1.164  -1.196  -1.122  -1.070  -1.034
46    I         0.597   0.639   0.598   0.517   0.584   0.466   0.393   0.463   0.323
47    K        -1.112  -1.054  -1.063  -1.150  -1.078  -1.084  -1.005  -0.948  -0.901
48    S        -1.112  -1.088  -1.068  -1.204  -1.158  -1.134  -1.005  -0.979  -0.905
49    V         0.280   0.424   0.053   0.326   0.502   0.012   0.277   0.480  -0.066
50    S        -0.914  -1.025  -1.040  -0.882  -1.032  -1.070  -0.772  -0.888  -0.872
51    S         0.938   0.934   0.760   0.817   0.818   0.586   0.976   0.968   0.637
52    I        -0.914  -0.941  -1.023  -0.658  -0.677  -0.768  -0.772  -0.802  -0.855
53    E         0.597   0.562   0.574   0.451   0.390   0.379   0.393   0.320   0.275
54    G         1.629   1.646   1.767   1.586   1.608   1.798   1.792   1.818   2.019
55    D         1.629   1.646   1.767   1.601   1.622   1.813   1.792   1.818   2.019
56    C         0.415   0.453   0.539   0.274   0.319   0.465   0.044   0.109   0.205
57    E         0.358   0.378   0.513   0.042   0.079   0.279  -0.073  -0.040   0.151
58    V         1.629   1.646   1.767   1.501   1.518   1.713   1.792   1.818   2.019
59    N        -0.596  -0.547  -0.606  -0.619  -0.553  -0.583  -0.656  -0.587  -0.634
60    Q         0.938   0.866   0.750   1.121   1.041   0.912   0.976   0.859   0.619
61    R         1.629   1.646   1.767   1.716   1.736   1.926   1.792   1.818   2.019
62    K         1.629   1.646   1.767   1.503   1.531   1.715   1.792   1.818   2.019
63    G         0.938   0.866   0.750   1.016   0.931   0.789   0.976   0.859   0.619
64    K         0.938   0.951   0.768   0.933   0.957   0.735   0.976   0.996   0.652
65    V         0.938   0.951   0.768   0.904   0.918   0.676   0.976   0.996   0.652
66    I         1.629   1.646   1.767   1.612   1.639   1.824   1.792   1.818   2.019
67    S         0.597   0.528   0.575   0.341   0.223   0.274   0.393   0.255   0.278
68    L         0.597   0.528   0.575   0.476   0.364   0.408   0.393   0.255   0.278
69    F         1.629   1.646   1.767   1.637   1.660   1.848   1.792   1.818   2.019
70    D         1.629   1.646   1.767   1.601   1.622   1.813   1.792   1.818   2.019
71    L        -0.022  -0.017  -0.085  -0.109  -0.117  -0.217  -0.189  -0.196  -0.284
72    K         0.938   0.951   0.768   0.903   0.927   0.671   0.976   0.996   0.652
73    I        -0.022   0.044  -0.075  -0.042   0.049  -0.151  -0.189  -0.106  -0.270
74    T        -1.112  -1.115  -1.073  -1.096  -1.108  -1.026  -1.005  -1.007  -0.910
75    V        -0.022  -0.032  -0.080  -0.063  -0.043  -0.122  -0.189  -0.184  -0.274
76    L        -1.112  -1.026  -1.057  -1.101  -0.985  -1.022  -1.005  -0.920  -0.895
77    I        -0.356  -0.354  -0.216  -0.420  -0.406  -0.205  -0.656  -0.650  -0.466
78    E        -1.430  -1.413  -1.406  -1.365  -1.340  -1.368  -1.122  -1.101  -1.043
79    G         1.629   1.646   1.767   1.586   1.608   1.798   1.792   1.818   2.019
80    H        -1.112  -1.138  -1.074  -0.931  -1.008  -0.928  -1.005  -1.028  -0.912
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    V        -1.232  -1.224  -1.108  -1.303  -1.284  -1.113  -1.122  -1.105  -0.943
87    D        -1.232  -1.246  -1.110  -1.254  -1.263  -1.065  -1.122  -1.122  -0.944
88    S        -1.232  -1.200  -1.104  -1.272  -1.215  -1.083  -1.122  -1.087  -0.940
89    K        -1.430  -1.369  -1.390  -1.257  -1.177  -1.240  -1.122  -1.062  -1.028
90    D        -0.914  -0.895  -0.744  -1.080  -1.047  -0.833  -1.005  -0.980  -0.787
91    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    F        -0.794  -0.765  -0.696  -0.866  -0.845  -0.735  -0.889  -0.865  -0.742
97    E        -0.158  -0.193  -0.134  -0.481  -0.513  -0.420  -0.423  -0.451  -0.362
98    G         1.629   1.646   1.767   1.586   1.608   1.798   1.792   1.818   2.019
99    S         0.415   0.407   0.523   0.032   0.012   0.185   0.044   0.019   0.172
100   I         0.938   0.934   0.760   1.011   1.011   0.762   0.976   0.968   0.637
101   N         0.280   0.303   0.028   0.375   0.402   0.003   0.277   0.310  -0.104
102   V        -0.022  -0.066  -0.089  -0.048  -0.092  -0.108  -0.189  -0.239  -0.289
103   P         1.629   1.646   1.767   1.687   1.707   1.897   1.792   1.818   2.019
104   E         1.629   1.646   1.767   1.510   1.535   1.723   1.792   1.818   2.019
105   V         0.415   0.431   0.530   0.095   0.115   0.250   0.044   0.067   0.185
106   A        -0.022  -0.052  -0.105  -0.080  -0.168  -0.252  -0.189  -0.255  -0.314
107   F        -0.158  -0.183  -0.130  -0.060  -0.073   0.020  -0.423  -0.439  -0.356
108   D         0.938   0.881   0.758   1.001   0.928   0.751   0.976   0.882   0.634
109   S        -0.022  -0.079  -0.106  -0.225  -0.323  -0.357  -0.189  -0.287  -0.315
110   E        -0.674  -0.669  -0.644  -0.751  -0.743  -0.687  -0.772  -0.763  -0.686
111   A        -1.112  -1.102  -1.070  -1.001  -0.978  -0.922  -1.005  -0.987  -0.906
112   S        -0.278  -0.268  -0.196  -0.510  -0.501  -0.441  -0.539  -0.525  -0.437
113   S        -0.596  -0.566  -0.622  -0.615  -0.586  -0.685  -0.656  -0.628  -0.655
114   Y        -0.022  -0.021  -0.073   0.131   0.156   0.040  -0.189  -0.170  -0.262
115   Q         0.597   0.528   0.575   0.577   0.443   0.475   0.393   0.255   0.278
116   F         1.629   1.646   1.767   1.637   1.660   1.848   1.792   1.818   2.019
117   D         0.280   0.274   0.028   0.426   0.417   0.065   0.277   0.269  -0.104
118   I         0.597   0.600   0.591   0.517   0.519   0.453   0.393   0.392   0.309
119   S        -0.596  -0.646  -0.647  -0.735  -0.814  -0.806  -0.656  -0.723  -0.685
120   I         1.629   1.646   1.767   1.612   1.639   1.824   1.792   1.818   2.019
121   F        -0.158  -0.133  -0.125  -0.105  -0.060  -0.047  -0.423  -0.381  -0.349
122   K        -1.232  -1.214  -1.117  -1.307  -1.285  -1.127  -1.122  -1.095  -0.950
123   E        -0.022  -0.112  -0.105  -0.093  -0.223  -0.217  -0.189  -0.315  -0.313
124   T        -0.596  -0.616  -0.633  -0.645  -0.702  -0.717  -0.656  -0.686  -0.669
125   S        -1.112  -1.165  -1.088  -1.159  -1.223  -1.102  -1.005  -1.043  -0.922
126   E        -0.596  -0.516  -0.605  -0.654  -0.534  -0.660  -0.656  -0.556  -0.633
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   L        -0.794  -0.711  -0.690  -0.971  -0.835  -0.824  -0.889  -0.795  -0.733
129   S        -1.112  -1.086  -1.056  -1.156  -1.101  -1.059  -1.005  -0.972  -0.894
130   E        -1.112  -1.025  -1.066  -0.973  -0.825  -0.907  -1.005  -0.908  -0.902
131   A        -0.674  -0.603  -0.635  -0.675  -0.604  -0.571  -0.772  -0.699  -0.678
132   K         0.280   0.386   0.038   0.351   0.487   0.035   0.277   0.428  -0.089
133   P        -0.278  -0.309  -0.201  -0.353  -0.421  -0.283  -0.539  -0.584  -0.444
134   L         0.938   1.026   0.772   0.932   1.044   0.705   0.976   1.110   0.660
135   I         0.415   0.394   0.520   0.178   0.120   0.300   0.044  -0.008   0.166
136   R        -0.022   0.039  -0.060   0.051   0.156  -0.027  -0.189  -0.091  -0.241
137   S        -0.794  -0.793  -0.689  -1.044  -1.014  -0.882  -0.889  -0.873  -0.732
138   E        -1.112  -1.070  -1.059  -1.075  -1.000  -0.972  -1.005  -0.952  -0.897
139   L         0.597   0.563   0.579   0.476   0.422   0.414   0.393   0.321   0.285
140   L        -0.356  -0.318  -0.208  -0.619  -0.563  -0.405  -0.656  -0.606  -0.456
141   P         1.629   1.646   1.767   1.687   1.707   1.897   1.792   1.818   2.019
142   K        -0.022   0.037  -0.070   0.007   0.110  -0.097  -0.189  -0.093  -0.260
143   L         0.938   0.866   0.750   0.948   0.866   0.705   0.976   0.859   0.619
144   R         1.629   1.646   1.767   1.716   1.736   1.926   1.792   1.818   2.019
145   Q        -1.232  -1.207  -1.107  -1.260  -1.224  -1.087  -1.122  -1.092  -0.942
146   I        -1.550  -1.563  -1.440  -1.440  -1.459  -1.300  -1.238  -1.240  -1.072
147   F         0.415   0.458   0.548   0.217   0.295   0.402   0.044   0.119   0.222
148   Q        -1.550  -1.526  -1.437  -1.375  -1.353  -1.199  -1.238  -1.212  -1.070
149   Q        -0.674  -0.667  -0.652  -0.685  -0.675  -0.627  -0.772  -0.762  -0.695
150   F         0.938   0.881   0.758   1.040   0.970   0.792   0.976   0.882   0.634
151   G        -0.022  -0.079  -0.106  -0.114  -0.233  -0.295  -0.189  -0.287  -0.315
152   K        -1.112  -1.086  -1.061  -0.927  -0.877  -0.837  -1.005  -0.969  -0.897
153   D        -0.340  -0.399  -0.562  -0.133  -0.229  -0.465  -0.306  -0.383  -0.574
154   L         1.629   1.646   1.767   1.533   1.561   1.745   1.792   1.818   2.019
155   L         0.415   0.436   0.535   0.167   0.203   0.335   0.044   0.075   0.195
156   A        -1.112  -1.097  -1.067  -1.045  -1.026  -0.982  -1.005  -0.990  -0.905
157   T         0.280   0.256   0.024   0.387   0.350   0.020   0.277   0.241  -0.110
158   H         0.597   0.629   0.603   0.739   0.788   0.706   0.393   0.446   0.334
159   G         0.415   0.452   0.537   0.107   0.176   0.263   0.044   0.108   0.200
160   N        -1.232  -1.245  -1.111  -1.329  -1.336  -1.146  -1.122  -1.122  -0.945
161   D         0.938   0.951   0.768   0.987   1.005   0.736   0.976   0.996   0.652
162   I         0.938   0.866   0.750   1.011   0.923   0.746   0.976   0.859   0.619
163   Q         0.938   0.866   0.750   1.111   1.027   0.888   0.976   0.859   0.619
164   V        -0.356  -0.356  -0.216  -0.549  -0.539  -0.324  -0.656  -0.653  -0.466
165   P        -0.596  -0.638  -0.631  -0.663  -0.713  -0.687  -0.656  -0.695  -0.666
166   E        -1.550  -1.563  -1.439  -1.488  -1.486  -1.312  -1.238  -1.239  -1.071
167   S        -0.340  -0.433  -0.567  -0.188  -0.323  -0.570  -0.306  -0.423  -0.579
168   Q        -0.674  -0.743  -0.657  -0.759  -0.844  -0.740  -0.772  -0.829  -0.699
169   V         0.877   0.765   0.712   0.884   0.743   0.692   0.878   0.687   0.547
170   K        -0.851  -0.843  -0.715  -1.027  -1.007  -0.837  -0.948  -0.933  -0.760
171   S         0.877   0.765   0.712   0.736   0.588   0.507   0.878   0.687   0.547
172   N        -0.851  -0.804  -0.713  -0.961  -0.892  -0.753  -0.948  -0.900  -0.758
173   Y        -0.714  -0.776  -0.679  -0.568  -0.662  -0.541  -0.796  -0.856  -0.719
174   T         0.877   0.765   0.712   0.920   0.768   0.689   0.878   0.687   0.547
175   R        -0.213  -0.204  -0.145  -0.340  -0.301  -0.222  -0.492  -0.471  -0.376
176   G         0.376   0.376   0.512   0.144   0.129   0.336  -0.035  -0.044   0.149
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   N         0.938   0.866   0.750   1.064   0.982   0.829   0.976   0.859   0.619
179   Q        -0.340  -0.458  -0.571  -0.074  -0.243  -0.438  -0.306  -0.453  -0.585
180   K        -1.550  -1.528  -1.433  -1.493  -1.448  -1.299  -1.238  -1.214  -1.067
181   S        -0.340  -0.289  -0.530  -0.331  -0.259  -0.599  -0.306  -0.240  -0.534
182   S        -0.914  -0.883  -1.009  -0.852  -0.811  -0.981  -0.772  -0.737  -0.840
183   F        -0.914  -0.845  -1.001  -0.688  -0.593  -0.859  -0.772  -0.692  -0.832
184   T        -1.868  -1.845  -1.727  -1.789  -1.763  -1.583  -1.355  -1.330  -1.169
185   E        -1.430  -1.443  -1.398  -1.301  -1.326  -1.298  -1.122  -1.128  -1.036
186   I        -1.550  -1.517  -1.431  -1.371  -1.317  -1.215  -1.238  -1.206  -1.066
187   K        -0.794  -0.815  -0.696  -0.877  -0.899  -0.733  -0.889  -0.899  -0.740
188   D        -0.794  -0.812  -0.696  -0.911  -0.935  -0.772  -0.889  -0.897  -0.741
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   S         0.168   0.181  -0.006   0.102   0.121  -0.135   0.117   0.129  -0.154
195   A        -0.350  -0.278  -0.200  -0.496  -0.363  -0.285  -0.644  -0.539  -0.444
196   S        -1.077  -1.060  -1.074  -0.926  -0.907  -0.988  -0.948  -0.929  -0.905
197   K        -1.234  -1.204  -1.121  -1.362  -1.343  -1.217  -1.109  -1.078  -0.951
198   P        -0.810  -0.837  -0.705  -0.868  -0.939  -0.745  -0.902  -0.924  -0.748
199   K        -0.810  -0.777  -0.697  -0.850  -0.792  -0.675  -0.902  -0.863  -0.740
200   K         0.461   0.492   0.550   0.227   0.279   0.343   0.134   0.186   0.227
201   N        -1.234  -1.190  -1.115  -1.179  -1.117  -1.030  -1.109  -1.060  -0.946
202   A        -0.810  -0.772  -0.705  -1.048  -0.989  -0.907  -0.902  -0.858  -0.748
203   L        -1.234  -1.212  -1.120  -1.322  -1.288  -1.146  -1.109  -1.081  -0.950
204   P        -1.234  -1.256  -1.121  -1.109  -1.145  -0.950  -1.109  -1.124  -0.951
205   S        -0.124  -0.154  -0.137  -0.362  -0.410  -0.377  -0.339  -0.385  -0.361
206   S        -0.794  -0.734  -0.689  -0.941  -0.857  -0.782  -0.889  -0.827  -0.734
207   T        -0.596  -0.564  -0.628  -0.673  -0.644  -0.752  -0.656  -0.623  -0.664
208   S        -0.596  -0.598  -0.627  -0.698  -0.696  -0.723  -0.656  -0.648  -0.661
209   T        -1.232  -1.230  -1.110  -1.339  -1.354  -1.165  -1.122  -1.110  -0.945
210   S         0.280   0.303   0.028   0.406   0.436   0.020   0.277   0.310  -0.104
211   A        -0.596  -0.561  -0.623  -0.444  -0.407  -0.466  -0.656  -0.620  -0.658
212   P        -1.232  -1.252  -1.111  -1.213  -1.235  -1.035  -1.122  -1.127  -0.945
213   V        -0.674  -0.673  -0.637  -0.895  -0.888  -0.811  -0.772  -0.764  -0.680
214   S        -1.430  -1.458  -1.415  -1.434  -1.482  -1.430  -1.122  -1.144  -1.050
215   S         0.280   0.209   0.014   0.253   0.166  -0.098   0.277   0.176  -0.125
216   T        -0.114  -0.107  -0.121  -0.221  -0.219  -0.284  -0.297  -0.287  -0.327
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   N        -0.650  -0.683  -0.654  -0.713  -0.769  -0.748  -0.695  -0.734  -0.685
229   K        -1.658  -1.636  -1.479  -1.604  -1.580  -1.353  -1.316  -1.291  -1.100
230   V        -0.487  -0.415  -0.578  -0.549  -0.445  -0.690  -0.492  -0.399  -0.593
231   P        -1.077  -1.060  -1.074  -1.048  -1.023  -1.021  -0.948  -0.929  -0.905
232   Q        -1.214  -1.189  -1.097  -1.301  -1.286  -1.122  -1.100  -1.073  -0.932
233   N        -0.714  -0.601  -0.648  -0.920  -0.757  -0.800  -0.796  -0.660  -0.683
234   G        -1.232  -1.248  -1.112  -1.150  -1.182  -0.982  -1.122  -1.124  -0.946
235   S        -1.232  -1.212  -1.104  -1.381  -1.354  -1.171  -1.122  -1.097  -0.940
236   G        -0.596  -0.646  -0.642  -0.420  -0.522  -0.534  -0.656  -0.720  -0.682
237   N         1.629   1.646   1.767   1.639   1.665   1.849   1.792   1.818   2.019
238   S         0.938   0.983   0.768   0.952   1.006   0.703   0.976   1.045   0.653
239   T        -0.022  -0.058  -0.092  -0.113  -0.154  -0.249  -0.189  -0.227  -0.295
240   S        -1.112  -1.105  -1.078  -1.150  -1.138  -1.104  -1.005  -0.994  -0.914
241   I        -0.794  -0.770  -0.686  -0.842  -0.792  -0.660  -0.889  -0.853  -0.728
242   Y        -0.914  -0.992  -1.032  -0.534  -0.675  -0.781  -0.772  -0.855  -0.864
243   L         0.280   0.149   0.000   0.353   0.183  -0.053   0.277   0.089  -0.145
244   E        -0.340  -0.458  -0.571  -0.250  -0.415  -0.607  -0.306  -0.453  -0.585
245   P        -0.340  -0.399  -0.562  -0.048  -0.124  -0.388  -0.306  -0.383  -0.574
246   T        -0.674  -0.701  -0.641  -0.859  -0.888  -0.787  -0.772  -0.791  -0.684
247   F         1.629   1.646   1.767   1.637   1.660   1.848   1.792   1.818   2.019
248   N        -0.914  -0.963  -1.025  -0.547  -0.617  -0.688  -0.772  -0.826  -0.856
249   V        -0.158  -0.193  -0.134  -0.346  -0.386  -0.288  -0.423  -0.451  -0.362
250   P        -0.158  -0.102  -0.122  -0.308  -0.247  -0.251  -0.423  -0.362  -0.348
251   S         0.938   0.983   0.768   0.995   1.051   0.745   0.976   1.045   0.653
252   S        -1.550  -1.531  -1.445  -1.482  -1.440  -1.331  -1.238  -1.215  -1.075
253   E         0.415   0.458   0.548   0.180   0.247   0.374   0.044   0.119   0.222
254   L         0.938   0.986   0.769   0.948   1.013   0.734   0.976   1.049   0.654
255   Y         0.938   0.934   0.760   1.191   1.189   0.963   0.976   0.968   0.637
256   E        -1.868  -1.781  -1.729  -1.563  -1.432  -1.376  -1.355  -1.281  -1.170
257   T         1.629   1.646   1.767   1.565   1.584   1.777   1.792   1.818   2.019
258   F         0.597   0.671   0.631   0.551   0.668   0.567   0.393   0.521   0.389
259   L         0.280   0.293   0.032   0.364   0.381   0.020   0.277   0.290  -0.098
260   D         1.629   1.646   1.767   1.601   1.622   1.813   1.792   1.818   2.019
261   K        -1.112  -1.025  -1.066  -0.951  -0.808  -0.877  -1.005  -0.908  -0.902
262   Q        -1.112  -1.120  -1.071  -0.840  -0.865  -0.762  -1.005  -1.011  -0.909
263   R         1.629   1.646   1.767   1.716   1.736   1.926   1.792   1.818   2.019
264   I        -0.356  -0.357  -0.217  -0.619  -0.627  -0.422  -0.656  -0.653  -0.468
265   L        -0.914  -0.819  -1.003  -0.690  -0.553  -0.850  -0.772  -0.663  -0.834
266   A         0.280   0.274   0.028   0.439   0.429   0.083   0.277   0.269  -0.104
267   W         0.597   0.562   0.574   0.730   0.666   0.640   0.393   0.320   0.275
268   T         0.415   0.426   0.525   0.032   0.045   0.188   0.044   0.056   0.175
269   R         1.629   1.646   1.767   1.716   1.736   1.926   1.792   1.818   2.019
270   S         0.415   0.394   0.520   0.056   0.018   0.210   0.044  -0.008   0.166
271   A        -0.596  -0.524  -0.617  -0.458  -0.356  -0.504  -0.656  -0.564  -0.650
272   Q        -0.340  -0.259  -0.548  -0.043   0.062  -0.356  -0.306  -0.201  -0.556
273   F        -1.430  -1.395  -1.396  -1.180  -1.126  -1.181  -1.122  -1.085  -1.034
274   F        -1.550  -1.552  -1.437  -1.223  -1.247  -1.078  -1.238  -1.232  -1.070
275   N        -1.430  -1.459  -1.406  -1.262  -1.305  -1.236  -1.122  -1.145  -1.042
276   S        -1.550  -1.530  -1.437  -1.567  -1.531  -1.387  -1.238  -1.215  -1.070
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   P        -0.815  -0.803  -0.724  -0.894  -0.875  -0.800  -0.893  -0.877  -0.766
287   K        -0.810  -0.835  -0.714  -0.843  -0.887  -0.720  -0.902  -0.922  -0.757
288   L        -0.226  -0.281  -0.170  -0.332  -0.404  -0.242  -0.487  -0.549  -0.403
289   E        -1.112  -1.094  -1.068  -1.079  -1.038  -0.989  -1.005  -0.978  -0.905
290   T        -0.596  -0.562  -0.635  -0.593  -0.561  -0.646  -0.656  -0.637  -0.671
291   K        -0.340  -0.315  -0.550  -0.142  -0.109  -0.448  -0.306  -0.277  -0.559
292   E        -0.794  -0.779  -0.705  -1.010  -0.986  -0.867  -0.889  -0.874  -0.750
293   K        -0.278  -0.289  -0.199  -0.507  -0.527  -0.413  -0.539  -0.555  -0.443
294   F         0.938   0.934   0.760   1.074   1.073   0.867   0.976   0.968   0.637
295   E        -1.232  -1.242  -1.109  -1.448  -1.458  -1.263  -1.122  -1.119  -0.944
296   L         0.938   0.986   0.769   0.952   1.015   0.741   0.976   1.049   0.654
297   F         1.629   1.646   1.767   1.637   1.660   1.848   1.792   1.818   2.019
298   G         0.280   0.149   0.000   0.454   0.291   0.094   0.277   0.089  -0.145
299   G         1.629   1.646   1.767   1.586   1.608   1.798   1.792   1.818   2.019
300   N         0.597   0.671   0.631   0.514   0.639   0.517   0.393   0.521   0.389
301   V         0.597   0.695   0.619   0.445   0.587   0.456   0.393   0.565   0.365
302   I        -0.914  -0.904  -1.027  -0.862  -0.854  -1.022  -0.772  -0.761  -0.859
303   S        -0.340  -0.259  -0.548  -0.139  -0.038  -0.441  -0.306  -0.201  -0.556
304   E        -0.022  -0.046  -0.096  -0.114  -0.147  -0.225  -0.189  -0.225  -0.302
305   L        -0.914  -0.947  -1.018  -0.636  -0.677  -0.809  -0.772  -0.805  -0.850
306   V        -0.158  -0.154  -0.125  -0.383  -0.384  -0.320  -0.423  -0.419  -0.353
307   S        -0.674  -0.746  -0.666  -0.937  -1.027  -0.915  -0.772  -0.833  -0.708
308   C        -0.340  -0.259  -0.548  -0.166  -0.060  -0.445  -0.306  -0.201  -0.556
309   E        -0.124  -0.123  -0.115  -0.257  -0.235  -0.233  -0.339  -0.321  -0.324
310   K        -0.794  -0.809  -0.705  -0.862  -0.902  -0.751  -0.889  -0.901  -0.750
311   D        -0.596  -0.580  -0.632  -0.477  -0.451  -0.526  -0.656  -0.635  -0.666
312   K        -0.596  -0.612  -0.626  -0.713  -0.715  -0.779  -0.656  -0.658  -0.657
313   K        -0.340  -0.319  -0.536  -0.227  -0.194  -0.505  -0.306  -0.276  -0.541
314   L         0.938   0.983   0.768   1.016   1.078   0.785   0.976   1.045   0.653
315   V         0.938   0.934   0.760   0.900   0.892   0.654   0.976   0.968   0.637
316   F        -0.596  -0.535  -0.617  -0.480  -0.379  -0.531  -0.656  -0.570  -0.647
317   H        -1.550  -1.577  -1.449  -1.412  -1.457  -1.275  -1.238  -1.250  -1.079
318   W         1.629   1.646   1.767   1.789   1.812   1.998   1.792   1.818   2.019
319   K         0.938   0.983   0.768   1.115   1.171   0.876   0.976   1.045   0.653
320   L         1.629   1.646   1.767   1.533   1.561   1.745   1.792   1.818   2.019
321   K        -1.232  -1.177  -1.102  -1.403  -1.337  -1.201  -1.122  -1.072  -0.938
322   D        -0.340  -0.458  -0.571  -0.170  -0.342  -0.546  -0.306  -0.453  -0.585
323   W         1.629   1.646   1.767   1.789   1.812   1.998   1.792   1.818   2.019
324   S        -0.596  -0.625  -0.644  -0.628  -0.672  -0.710  -0.656  -0.702  -0.682
325   A        -1.550  -1.548  -1.432  -1.397  -1.391  -1.245  -1.238  -1.228  -1.066
326   P         0.280   0.303   0.028   0.420   0.449   0.070   0.277   0.310  -0.104
327   F         0.280   0.303   0.028   0.665   0.698   0.332   0.277   0.310  -0.104
328   N        -0.158  -0.122  -0.117  -0.091  -0.042  -0.017  -0.423  -0.377  -0.342
329   S         0.415   0.431   0.530   0.056   0.079   0.223   0.044   0.067   0.185
330   T        -0.356  -0.319  -0.198  -0.579  -0.533  -0.347  -0.656  -0.607  -0.443
331   I         0.597   0.578   0.575   0.476   0.448   0.408   0.393   0.351   0.278
332   E        -1.112  -1.158  -1.086  -1.167  -1.234  -1.160  -1.005  -1.040  -0.922
333   M        -0.794  -0.830  -0.700  -0.740  -0.780  -0.583  -0.889  -0.917  -0.746
334   T        -0.596  -0.533  -0.625  -0.632  -0.560  -0.674  -0.656  -0.591  -0.661
335   F         0.597   0.671   0.631   0.551   0.668   0.567   0.393   0.521   0.389
336   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   S        -1.430  -1.449  -1.420  -1.403  -1.425  -1.393  -1.122  -1.136  -1.054
339   Q         0.938   0.881   0.758   1.087   1.016   0.848   0.976   0.882   0.634
340   E        -1.112  -1.154  -1.085  -1.161  -1.220  -1.141  -1.005  -1.035  -0.920
341   F        -1.232  -1.199  -1.115  -1.186  -1.133  -1.003  -1.122  -1.084  -0.948
342   H        -0.794  -0.815  -0.702  -0.803  -0.847  -0.711  -0.889  -0.901  -0.747
343   E        -0.340  -0.458  -0.571  -0.205  -0.362  -0.527  -0.306  -0.453  -0.585
344   T         1.629   1.646   1.767   1.565   1.584   1.777   1.792   1.818   2.019
345   K         0.280   0.149   0.000   0.315   0.142  -0.097   0.277   0.089  -0.145
346   L         0.597   0.606   0.588   0.554   0.569   0.547   0.393   0.403   0.304
347   Q        -1.232  -1.204  -1.110  -1.167  -1.109  -0.987  -1.122  -1.088  -0.945
348   V         0.280   0.197   0.006   0.380   0.278   0.045   0.277   0.157  -0.137
349   K        -0.914  -0.975  -1.033  -0.788  -0.879  -0.978  -0.772  -0.838  -0.865
350   W         0.280   0.243   0.018   0.666   0.625   0.327   0.277   0.222  -0.118
351   T        -0.596  -0.671  -0.644  -0.743  -0.851  -0.808  -0.656  -0.739  -0.682
352   G         0.938   0.934   0.760   0.985   0.983   0.737   0.976   0.968   0.637
353   I         0.597   0.528   0.575   0.517   0.389   0.421   0.393   0.255   0.278
354   P         1.629   1.646   1.767   1.687   1.707   1.897   1.792   1.818   2.019
355   V         0.597   0.579   0.576   0.445   0.408   0.382   0.393   0.353   0.280
356   G         1.629   1.646   1.767   1.586   1.608   1.798   1.792   1.818   2.019
357   E         0.415   0.407   0.523   0.180   0.164   0.336   0.044   0.019   0.172
358   E         1.629   1.646   1.767   1.510   1.535   1.723   1.792   1.818   2.019
359   D         0.415   0.400   0.519   0.173   0.129   0.293   0.044   0.004   0.163
360   R        -0.022  -0.107  -0.107   0.065  -0.076  -0.103  -0.189  -0.311  -0.317
361   V         0.938   0.951   0.768   0.915   0.927   0.700   0.976   0.996   0.652
362   R        -0.022  -0.099  -0.106   0.077  -0.035  -0.079  -0.189  -0.293  -0.315
363   A        -0.596  -0.591  -0.627  -0.505  -0.503  -0.540  -0.656  -0.652  -0.662
364   N         1.629   1.646   1.767   1.639   1.665   1.849   1.792   1.818   2.019
365   F         0.280   0.149   0.000   0.504   0.342   0.140   0.277   0.089  -0.145
366   E         0.280   0.149   0.000   0.364   0.201  -0.005   0.277   0.089  -0.145
367   E         0.597   0.597   0.583   0.451   0.448   0.395   0.393   0.387   0.293
368   Y         0.938   0.986   0.769   1.197   1.255   0.989   0.976   1.049   0.654
369   Y         1.629   1.646   1.767   1.769   1.791   1.978   1.792   1.818   2.019
370   V         0.358   0.374   0.512   0.043   0.062   0.273  -0.073  -0.049   0.148
371   R         0.938   0.951   0.768   1.115   1.132   0.875   0.976   0.996   0.652
372   S         0.280   0.197   0.006   0.261   0.161  -0.095   0.277   0.157  -0.137
373   I         1.629   1.646   1.767   1.612   1.639   1.824   1.792   1.818   2.019
374   K         0.938   0.951   0.768   0.926   0.951   0.722   0.976   0.996   0.652
375   L        -1.232  -1.268  -1.116  -1.247  -1.283  -1.064  -1.122  -1.139  -0.949
376   T         0.280   0.212   0.014   0.385   0.287  -0.001   0.277   0.179  -0.124
377   F         1.629   1.646   1.767   1.637   1.660   1.848   1.792   1.818   2.019
378   G         1.629   1.646   1.767   1.586   1.608   1.798   1.792   1.818   2.019
379   F         1.629   1.646   1.767   1.637   1.660   1.848   1.792   1.818   2.019
380   G         1.629   1.646   1.767   1.586   1.608   1.798   1.792   1.818   2.019
381   A         0.938   0.881   0.758   1.017   0.942   0.775   0.976   0.882   0.634
382   V        -0.022  -0.014  -0.083  -0.083  -0.076  -0.161  -0.189  -0.178  -0.282
383   L         1.629   1.646   1.767   1.533   1.561   1.745   1.792   1.818   2.019
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12449
Output conservation file - output/Q12449
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
