1     M         1.608   1.691   1.755   1.814   1.928   2.032   1.781   1.901   2.015
2     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     S         0.486   0.391   0.456   0.383   0.206   0.313   0.302   0.101   0.180
6     S        -0.123  -0.154  -0.275  -0.138  -0.211  -0.390  -0.191  -0.244  -0.414
7     T        -0.410  -0.333  -0.330  -0.493  -0.382  -0.384  -0.630  -0.510  -0.496
8     L         0.338   0.427   0.452   0.078   0.216   0.256   0.028   0.168   0.171
9     P         1.608   1.691   1.755   1.654   1.766   1.877   1.781   1.901   2.015
10    L         0.225   0.302   0.404  -0.144  -0.008   0.149  -0.191  -0.072   0.077
11    H         0.338   0.427   0.452   0.372   0.515   0.520   0.028   0.168   0.171
12    M        -1.089  -1.051  -0.923  -1.166  -1.102  -0.916  -1.117  -1.032  -0.872
13    Y        -0.940  -1.047  -0.912  -0.797  -0.928  -0.750  -0.956  -1.028  -0.861
14    I         1.608   1.691   1.755   1.393   1.519   1.623   1.781   1.901   2.015
15    R         1.608   1.691   1.755   1.720   1.819   1.940   1.781   1.901   2.015
16    P         0.790   0.620   0.601   0.964   0.737   0.702   0.815   0.520   0.455
17    L         0.790   0.620   0.601   0.654   0.399   0.346   0.815   0.520   0.455
18    I        -0.940  -1.040  -0.900  -1.038  -1.179  -0.982  -0.956  -1.019  -0.847
19    I         0.019  -0.244  -0.247  -0.027  -0.383  -0.382   0.010  -0.358  -0.373
20    E        -0.299  -0.432  -0.321  -0.457  -0.632  -0.468  -0.473  -0.630  -0.489
21    D         0.790   0.620   0.601   0.888   0.655   0.576   0.815   0.520   0.455
22    L        -1.484  -1.281  -1.332  -1.557  -1.185  -1.305  -1.278  -1.045  -1.050
23    K        -0.694  -0.700  -0.821  -0.515  -0.541  -0.741  -0.634  -0.640  -0.755
24    Q        -0.299  -0.444  -0.327  -0.216  -0.472  -0.309  -0.473  -0.648  -0.497
25    I        -1.089  -1.007  -0.917  -1.166  -1.066  -0.928  -1.117  -1.000  -0.869
26    L        -0.694  -0.644  -0.814  -0.614  -0.569  -0.886  -0.634  -0.578  -0.746
27    N        -1.335  -1.218  -1.295  -1.320  -1.162  -1.249  -1.117  -0.982  -1.012
28    L         0.790   0.721   0.609   0.698   0.617   0.454   0.815   0.693   0.470
29    E         0.790   0.721   0.609   0.690   0.622   0.420   0.815   0.693   0.470
30    S        -0.940  -0.842  -0.860  -0.882  -0.716  -0.732  -0.956  -0.807  -0.803
31    Q        -0.940  -0.924  -0.873  -0.939  -0.957  -0.838  -0.956  -0.909  -0.819
32    G         0.019  -0.244  -0.247   0.222  -0.140  -0.129   0.010  -0.358  -0.373
33    F         1.608   1.691   1.755   1.737   1.848   1.957   1.781   1.901   2.015
34    P         1.608   1.691   1.755   1.681   1.795   1.902   1.781   1.901   2.015
35    P         0.414   0.397   0.436   0.315   0.254   0.262   0.171   0.113   0.140
36    N        -1.879  -1.819  -1.721  -1.742  -1.624  -1.480  -1.439  -1.353  -1.210
37    E         0.790   0.721   0.609   0.730   0.680   0.505   0.815   0.693   0.470
38    R         0.790   0.721   0.609   0.971   0.858   0.684   0.815   0.693   0.470
39    A         0.019   0.263  -0.151   0.290   0.595   0.059   0.010   0.360  -0.234
40    S         0.019  -0.010  -0.205   0.081   0.030  -0.242   0.010  -0.028  -0.313
41    E        -1.484  -1.442  -1.354  -1.425  -1.311  -1.190  -1.278  -1.201  -1.068
42    E        -0.694  -0.656  -0.806  -0.683  -0.614  -0.837  -0.634  -0.592  -0.738
43    I        -0.694  -0.644  -0.814  -0.597  -0.531  -0.794  -0.634  -0.578  -0.746
44    I        -0.299  -0.266  -0.283  -0.477  -0.405  -0.422  -0.473  -0.392  -0.430
45    S        -1.484  -1.386  -1.344  -1.651  -1.487  -1.424  -1.278  -1.152  -1.060
46    F        -0.299  -0.359  -0.294  -0.126  -0.196  -0.128  -0.473  -0.522  -0.447
47    R         1.608   1.691   1.755   1.720   1.819   1.940   1.781   1.901   2.015
48    L         0.790   0.620   0.601   0.698   0.469   0.441   0.815   0.520   0.455
49    I        -1.484  -1.367  -1.343  -1.516  -1.306  -1.322  -1.278  -1.134  -1.059
50    N        -2.275  -2.169  -2.050  -1.833  -1.687  -1.511  -1.600  -1.478  -1.322
51    C         0.414   0.395   0.436   0.564   0.493   0.538   0.171   0.108   0.140
52    P         1.608   1.691   1.755   1.681   1.795   1.902   1.781   1.901   2.015
53    E         1.608   1.691   1.755   1.439   1.581   1.667   1.781   1.901   2.015
54    L         0.790   0.620   0.601   0.654   0.399   0.346   0.815   0.520   0.455
55    C         0.019  -0.097  -0.217   0.398   0.227   0.016   0.010  -0.162  -0.331
56    S        -0.299  -0.274  -0.319  -0.495  -0.560  -0.547  -0.473  -0.476  -0.488
57    G         1.608   1.691   1.755   1.610   1.717   1.834   1.781   1.901   2.015
58    L         1.608   1.691   1.755   1.425   1.544   1.654   1.781   1.901   2.015
59    F         1.608   1.691   1.755   1.737   1.848   1.957   1.781   1.901   2.015
60    I         0.019  -0.049  -0.202  -0.032  -0.129  -0.325   0.010  -0.102  -0.309
61    R         0.790   0.620   0.601   0.997   0.747   0.724   0.815   0.520   0.455
62    E        -0.694  -0.880  -0.862  -0.699  -0.960  -0.944  -0.634  -0.844  -0.802
63    I        -1.335  -1.259  -1.317  -1.083  -0.938  -1.124  -1.117  -1.022  -1.032
64    E        -1.335  -1.265  -1.300  -1.231  -1.075  -1.229  -1.117  -1.027  -1.017
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -0.466  -0.316  -0.337  -0.628  -0.396  -0.431  -0.684  -0.460  -0.502
79    -        -1.158  -1.097  -0.956  -1.395  -1.287  -1.086  -1.177  -1.081  -0.905
80    G         0.709   0.797   0.576   0.809   0.928   0.621   0.685   0.819   0.408
81    K        -0.123  -0.218  -0.291  -0.135  -0.301  -0.430  -0.191  -0.328  -0.437
82    E        -0.410  -0.370  -0.337  -0.627  -0.569  -0.479  -0.630  -0.572  -0.510
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   V         0.338   0.449   0.443   0.118   0.298   0.235   0.028   0.209   0.154
104   K        -1.045  -1.046  -0.925  -1.342  -1.357  -1.158  -1.068  -1.033  -0.874
105   K        -1.335  -1.400  -1.336  -1.224  -1.345  -1.236  -1.117  -1.159  -1.050
106   E         0.790   0.620   0.601   0.690   0.466   0.406   0.815   0.520   0.455
107   T         0.246   0.309   0.404   0.015   0.097   0.245  -0.151  -0.059   0.076
108   L         1.608   1.691   1.755   1.425   1.544   1.654   1.781   1.901   2.015
109   I         0.790   0.721   0.609   0.666   0.592   0.424   0.815   0.693   0.470
110   G         0.790   0.721   0.609   0.891   0.796   0.643   0.815   0.693   0.470
111   H         0.790   0.721   0.609   1.026   0.928   0.759   0.815   0.693   0.470
112   I         0.246   0.298   0.402  -0.157  -0.074   0.097  -0.151  -0.080   0.074
113   M        -1.089  -0.956  -0.916  -1.255  -1.080  -0.990  -1.117  -0.937  -0.866
114   G        -0.396  -0.465  -0.332  -0.457  -0.551  -0.327  -0.634  -0.681  -0.504
115   T         0.790   0.620   0.601   0.923   0.660   0.625   0.815   0.520   0.455
116   K         0.790   0.620   0.601   0.841   0.614   0.589   0.815   0.520   0.455
117   I        -0.299  -0.397  -0.321  -0.469  -0.580  -0.438  -0.473  -0.594  -0.489
118   P        -1.879  -1.828  -1.731  -1.551  -1.509  -1.336  -1.439  -1.360  -1.217
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   H        -0.694  -0.422  -0.790  -0.631  -0.261  -0.785  -0.634  -0.277  -0.719
128   E        -1.089  -1.066  -0.922  -1.289  -1.229  -1.026  -1.117  -1.049  -0.874
129   Y        -1.879  -1.825  -1.729  -1.659  -1.622  -1.469  -1.439  -1.358  -1.216
130   I         0.790   0.620   0.601   0.666   0.445   0.411   0.815   0.520   0.455
131   T         1.608   1.691   1.755   1.672   1.778   1.894   1.781   1.901   2.015
132   I        -1.879  -1.763  -1.712  -1.808  -1.570  -1.564  -1.439  -1.306  -1.203
133   E        -0.940  -0.853  -0.866  -1.118  -0.962  -0.975  -0.956  -0.820  -0.813
134   S         1.608   1.691   1.755   1.521   1.623   1.747   1.781   1.901   2.015
135   M         1.608   1.691   1.755   1.814   1.928   2.032   1.781   1.901   2.015
136   -        -0.466  -0.414  -0.356  -0.522  -0.436  -0.398  -0.684  -0.604  -0.529
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   G        -1.506  -1.474  -1.363  -1.485  -1.476  -1.286  -1.287  -1.221  -1.075
146   K        -1.879  -1.725  -1.707  -1.688  -1.474  -1.423  -1.439  -1.269  -1.199
147   L        -1.335  -1.259  -1.317  -1.260  -1.170  -1.281  -1.117  -1.022  -1.032
148   Q         0.414   0.567   0.495   0.501   0.727   0.604   0.171   0.425   0.256
149   V        -1.484  -1.379  -1.345  -1.428  -1.247  -1.227  -1.278  -1.141  -1.060
150   E         0.019  -0.097  -0.217  -0.023  -0.184  -0.377   0.010  -0.162  -0.331
151   S        -1.335  -1.366  -1.326  -1.220  -1.303  -1.198  -1.117  -1.129  -1.041
152   S         0.414   0.324   0.411   0.227   0.025   0.179   0.171  -0.029   0.091
153   N        -1.484  -1.442  -1.348  -1.350  -1.317  -1.167  -1.278  -1.202  -1.063
154   H        -1.484  -1.323  -1.332  -1.221  -1.011  -0.987  -1.278  -1.100  -1.051
155   I         0.790   0.721   0.609   0.666   0.592   0.424   0.815   0.693   0.470
156   G         0.414   0.400   0.433   0.345   0.287   0.342   0.171   0.118   0.134
157   I         0.414   0.427   0.436   0.120   0.135   0.141   0.171   0.169   0.140
158   H         1.608   1.691   1.755   1.754   1.859   1.974   1.781   1.901   2.015
159   S         0.414   0.453   0.448   0.261   0.292   0.295   0.171   0.218   0.165
160   V         0.246   0.299   0.402  -0.084  -0.023   0.138  -0.151  -0.078   0.074
161   V         0.019  -0.244  -0.247   0.226  -0.167  -0.164   0.010  -0.358  -0.373
162   I         0.790   0.721   0.609   0.666   0.592   0.424   0.815   0.693   0.470
163   K        -0.940  -0.826  -0.869  -0.825  -0.664  -0.711  -0.956  -0.822  -0.818
164   P         1.608   1.691   1.755   1.681   1.795   1.902   1.781   1.901   2.015
165   E        -0.694  -0.718  -0.824  -0.633  -0.649  -0.784  -0.634  -0.660  -0.758
166   Y        -0.545  -0.478  -0.376  -0.388  -0.309  -0.147  -0.795  -0.697  -0.558
167   Q         0.414   0.395   0.436   0.489   0.431   0.477   0.171   0.108   0.140
168   K         0.246   0.316   0.408  -0.047   0.053   0.201  -0.151  -0.045   0.085
169   K         0.790   0.620   0.601   0.841   0.621   0.589   0.815   0.520   0.455
170   N         0.019  -0.244  -0.247   0.248  -0.156  -0.196   0.010  -0.358  -0.373
171   L         0.019  -0.244  -0.247  -0.034  -0.401  -0.431   0.010  -0.358  -0.373
172   A         0.246   0.316   0.408   0.069   0.153   0.310  -0.151  -0.045   0.085
173   T        -0.694  -0.842  -0.852  -0.488  -0.773  -0.768  -0.634  -0.805  -0.791
174   L         0.019  -0.244  -0.247  -0.082  -0.488  -0.529   0.010  -0.358  -0.373
175   L         1.608   1.691   1.755   1.425   1.544   1.654   1.781   1.901   2.015
176   L        -0.299  -0.430  -0.321  -0.470  -0.672  -0.488  -0.473  -0.628  -0.489
177   T        -0.940  -1.047  -0.912  -0.833  -1.009  -0.800  -0.956  -1.028  -0.861
178   D         0.790   0.620   0.601   0.888   0.655   0.576   0.815   0.520   0.455
179   Y         1.608   1.691   1.755   1.756   1.871   1.976   1.781   1.901   2.015
180   I         0.019  -0.244  -0.247  -0.089  -0.485  -0.505   0.010  -0.358  -0.373
181   Q         1.608   1.691   1.755   1.754   1.875   1.974   1.781   1.901   2.015
182   K         0.019  -0.244  -0.247   0.152  -0.210  -0.208   0.010  -0.358  -0.373
183   L        -0.694  -0.880  -0.862  -0.689  -0.973  -0.915  -0.634  -0.844  -0.802
184   S         0.790   0.620   0.601   0.827   0.604   0.602   0.815   0.520   0.455
185   N         0.019  -0.244  -0.247   0.305  -0.058  -0.084   0.010  -0.358  -0.373
186   Q         0.019  -0.244  -0.247   0.348  -0.016  -0.037   0.010  -0.358  -0.373
187   E        -0.940  -1.047  -0.912  -1.051  -1.153  -0.967  -0.956  -1.028  -0.861
188   I        -0.396  -0.271  -0.307  -0.709  -0.536  -0.570  -0.634  -0.475  -0.476
189   G         0.019  -0.244  -0.247   0.187  -0.203  -0.197   0.010  -0.358  -0.373
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   N        -0.545  -0.472  -0.374  -0.692  -0.615  -0.459  -0.795  -0.690  -0.556
194   K        -0.299  -0.062  -0.249  -0.240   0.119  -0.157  -0.473  -0.122  -0.385
195   I         0.019  -0.042  -0.201  -0.007  -0.074  -0.279   0.010  -0.093  -0.307
196   V        -0.299  -0.397  -0.321  -0.389  -0.575  -0.466  -0.473  -0.594  -0.489
197   L         0.246   0.291   0.403  -0.304  -0.238  -0.057  -0.151  -0.093   0.075
198   I         1.608   1.691   1.755   1.393   1.519   1.623   1.781   1.901   2.015
199   A         0.019  -0.049  -0.202   0.248   0.096  -0.096   0.010  -0.102  -0.309
200   H         0.019   0.040  -0.187   0.301   0.318  -0.025   0.010   0.037  -0.286
201   E        -0.940  -0.965  -0.890  -1.079  -1.071  -0.959  -0.956  -0.957  -0.841
202   P        -0.940  -0.792  -0.861  -0.977  -0.773  -0.813  -0.956  -0.788  -0.811
203   L         0.790   0.721   0.609   0.710   0.636   0.480   0.815   0.693   0.470
204   I        -0.396  -0.400  -0.310  -0.641  -0.585  -0.450  -0.634  -0.600  -0.477
205   P         1.608   1.691   1.755   1.681   1.795   1.902   1.781   1.901   2.015
206   F         1.608   1.691   1.755   1.737   1.848   1.957   1.781   1.901   2.015
207   Y         1.608   1.691   1.755   1.785   1.904   2.003   1.781   1.901   2.015
208   E         1.608   1.691   1.755   1.439   1.581   1.667   1.781   1.901   2.015
209   R        -0.396  -0.465  -0.332  -0.515  -0.635  -0.416  -0.634  -0.681  -0.504
210   V        -0.299  -0.257  -0.317  -0.628  -0.633  -0.660  -0.473  -0.459  -0.486
211   G         1.608   1.691   1.755   1.610   1.717   1.834   1.781   1.901   2.015
212   F         1.608   1.691   1.755   1.737   1.848   1.957   1.781   1.901   2.015
213   K        -1.335  -1.224  -1.305  -1.098  -0.956  -1.029  -1.117  -0.975  -1.022
214   I        -0.694  -0.422  -0.790  -0.492  -0.075  -0.696  -0.634  -0.277  -0.719
215   I        -0.940  -0.885  -0.881  -1.176  -1.030  -1.026  -0.956  -0.851  -0.826
216   A         0.414   0.611   0.524   0.345   0.634   0.502   0.171   0.504   0.311
217   E        -0.694  -0.880  -0.862  -0.688  -0.933  -0.925  -0.634  -0.844  -0.802
218   N         0.246   0.372   0.432  -0.008   0.179   0.280  -0.151   0.064   0.132
219   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   D        -0.396  -0.313  -0.320  -0.652  -0.508  -0.521  -0.634  -0.516  -0.490
225   K        -0.123   0.121  -0.217   0.180   0.534  -0.008  -0.191   0.163  -0.330
226   N        -0.123   0.121  -0.217  -0.083   0.264  -0.223  -0.191   0.163  -0.330
227   F         0.338   0.373   0.427   0.376   0.417   0.486   0.028   0.067   0.124
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   A        -1.335  -1.400  -1.336  -1.072  -1.211  -1.102  -1.117  -1.159  -1.050
230   E        -0.940  -0.896  -0.868  -0.922  -0.836  -0.819  -0.956  -0.877  -0.815
231   Q        -1.335  -1.397  -1.335  -1.134  -1.287  -1.172  -1.117  -1.156  -1.050
232   K        -0.545  -0.529  -0.393  -0.723  -0.698  -0.483  -0.795  -0.761  -0.580
233   W         1.608   1.691   1.755   1.899   2.018   2.115   1.781   1.901   2.015
234   I        -0.940  -0.885  -0.881  -0.823  -0.672  -0.690  -0.956  -0.851  -0.826
235   D         0.790   0.901   0.632   0.934   1.108   0.725   0.815   0.984   0.513
236   M         0.414   0.453   0.448   0.438   0.479   0.400   0.171   0.218   0.165
237   E        -1.484  -1.524  -1.373  -1.395  -1.400  -1.184  -1.278  -1.267  -1.084
238   R        -0.940  -1.047  -0.912  -0.897  -1.012  -0.830  -0.956  -1.028  -0.861
239   E        -0.396  -0.465  -0.332  -0.643  -0.685  -0.514  -0.634  -0.681  -0.504
240   L         0.790   0.620   0.601   0.654   0.399   0.346   0.815   0.520   0.455
241   I        -0.123  -0.153  -0.276  -0.079  -0.158  -0.395  -0.191  -0.243  -0.416
242   K        -0.288  -0.258  -0.337  -0.298  -0.248  -0.366  -0.428  -0.376  -0.502
243   E         0.610   0.655   0.508   0.454   0.523   0.299   0.519   0.580   0.281
244   E        -0.288  -0.258  -0.337  -0.419  -0.369  -0.468  -0.428  -0.376  -0.502
245   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   D        -0.123  -0.218  -0.291  -0.047  -0.199  -0.337  -0.191  -0.328  -0.437
247   N        -1.506  -1.391  -1.346  -1.451  -1.252  -1.234  -1.287  -1.136  -1.060
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12447
Output conservation file - output/Q12447
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
