1     M         1.651   1.651   1.651   2.027   2.027   2.027   1.651   1.651   1.651
2     A        -0.603  -0.603  -0.603  -0.649  -0.649  -0.649  -0.603  -0.603  -0.603
3     S        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
4     Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     A        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
8     L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
9     L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
10    L        -0.603  -0.603  -0.603  -0.909  -0.909  -0.909  -0.603  -0.603  -0.603
11    P        -0.603  -0.603  -0.603  -0.574  -0.574  -0.574  -0.603  -0.603  -0.603
12    V        -0.603  -0.603  -0.603  -0.537  -0.537  -0.537  -0.603  -0.603  -0.603
13    I        -0.603  -0.603  -0.603  -0.639  -0.639  -0.639  -0.603  -0.603  -0.603
14    E        -0.603  -0.603  -0.603  -0.939  -0.939  -0.939  -0.603  -0.603  -0.603
15    S        -0.603  -0.603  -0.603  -0.483  -0.483  -0.483  -0.603  -0.603  -0.603
16    T        -0.603  -0.603  -0.603  -0.705  -0.705  -0.705  -0.603  -0.603  -0.603
17    P        -0.603  -0.603  -0.603  -0.322  -0.322  -0.322  -0.603  -0.603  -0.603
18    L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
19    H         1.651   1.651   1.651   1.844   1.844   1.844   1.651   1.651   1.651
20    Q        -0.603  -0.603  -0.603  -0.519  -0.519  -0.519  -0.603  -0.603  -0.603
21    I         1.651   1.651   1.651   1.707   1.707   1.707   1.651   1.651   1.651
22    T         1.651   1.651   1.651   1.618   1.618   1.618   1.651   1.651   1.651
23    K         1.651   1.651   1.651   1.542   1.542   1.542   1.651   1.651   1.651
24    V        -0.603  -0.603  -0.603  -0.402  -0.402  -0.402  -0.603  -0.603  -0.603
25    A         1.651   1.651   1.651   1.694   1.694   1.694   1.651   1.651   1.651
26    L        -0.603  -0.603  -0.603  -0.929  -0.929  -0.929  -0.603  -0.603  -0.603
27    T        -0.603  -0.603  -0.603  -0.677  -0.677  -0.677  -0.603  -0.603  -0.603
28    T        -0.603  -0.603  -0.603  -0.705  -0.705  -0.705  -0.603  -0.603  -0.603
29    T        -0.603  -0.603  -0.603  -0.510  -0.510  -0.510  -0.603  -0.603  -0.603
30    L        -0.603  -0.603  -0.603  -0.879  -0.879  -0.879  -0.603  -0.603  -0.603
31    T         1.651   1.651   1.651   1.618   1.618   1.618   1.651   1.651   1.651
32    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    V        -0.603  -0.603  -0.603  -0.375  -0.375  -0.375  -0.603  -0.603  -0.603
45    P         1.651   1.651   1.651   1.719   1.719   1.719   1.651   1.651   1.651
46    L        -0.603  -0.603  -0.603  -1.060  -1.060  -1.060  -0.603  -0.603  -0.603
47    T        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
48    K         1.651   1.651   1.651   1.542   1.542   1.542   1.651   1.651   1.651
49    S        -0.603  -0.603  -0.603  -0.519  -0.519  -0.519  -0.603  -0.603  -0.603
50    L        -0.603  -0.603  -0.603  -0.820  -0.820  -0.820  -0.603  -0.603  -0.603
51    Q        -0.603  -0.603  -0.603  -0.438  -0.438  -0.438  -0.603  -0.603  -0.603
52    L        -0.603  -0.603  -0.603  -0.999  -0.999  -0.999  -0.603  -0.603  -0.603
53    Y        -0.603  -0.603  -0.603  -0.791  -0.791  -0.791  -0.603  -0.603  -0.603
54    E        -0.603  -0.603  -0.603  -0.429  -0.429  -0.429  -0.603  -0.603  -0.603
55    K        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
56    A        -0.603  -0.603  -0.603  -0.939  -0.939  -0.939  -0.603  -0.603  -0.603
57    Q        -0.603  -0.603  -0.603  -0.465  -0.465  -0.465  -0.603  -0.603  -0.603
58    R        -0.603  -0.603  -0.603  -0.593  -0.593  -0.593  -0.603  -0.603  -0.603
59    R        -0.603  -0.603  -0.603  -0.429  -0.429  -0.429  -0.603  -0.603  -0.603
60    Q        -0.603  -0.603  -0.603  -0.465  -0.465  -0.465  -0.603  -0.603  -0.603
61    D        -0.603  -0.603  -0.603  -0.483  -0.483  -0.483  -0.603  -0.603  -0.603
62    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    R        -0.603  -0.603  -0.603  -0.537  -0.537  -0.537  -0.603  -0.603  -0.603
64    A        -0.603  -0.603  -0.603  -0.519  -0.519  -0.519  -0.603  -0.603  -0.603
65    S        -0.603  -0.603  -0.603  -0.677  -0.677  -0.677  -0.603  -0.603  -0.603
66    L        -0.603  -0.603  -0.603  -0.909  -0.909  -0.909  -0.603  -0.603  -0.603
67    K         1.651   1.651   1.651   1.542   1.542   1.542   1.651   1.651   1.651
68    A        -0.603  -0.603  -0.603  -0.593  -0.593  -0.593  -0.603  -0.603  -0.603
69    L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
70    E         1.651   1.651   1.651   1.694   1.694   1.694   1.651   1.651   1.651
71    S        -0.603  -0.603  -0.603  -0.734  -0.734  -0.734  -0.603  -0.603  -0.603
72    I        -0.603  -0.603  -0.603  -0.929  -0.929  -0.929  -0.603  -0.603  -0.603
73    I        -0.603  -0.603  -0.603  -0.447  -0.447  -0.447  -0.603  -0.603  -0.603
74    Y         1.651   1.651   1.651   1.881   1.881   1.881   1.651   1.651   1.651
75    Q        -0.603  -0.603  -0.603  -0.519  -0.519  -0.519  -0.603  -0.603  -0.603
76    T        -0.603  -0.603  -0.603  -0.510  -0.510  -0.510  -0.603  -0.603  -0.603
77    H         1.651   1.651   1.651   1.844   1.844   1.844   1.651   1.651   1.651
78    F         1.651   1.651   1.651   1.807   1.807   1.807   1.651   1.651   1.651
79    Q        -0.603  -0.603  -0.603  -0.331  -0.331  -0.331  -0.603  -0.603  -0.603
80    W        -0.603  -0.603  -0.603  -0.696  -0.696  -0.696  -0.603  -0.603  -0.603
81    N        -0.603  -0.603  -0.603  -0.969  -0.969  -0.969  -0.603  -0.603  -0.603
82    N         1.651   1.651   1.651   1.656   1.656   1.656   1.651   1.651   1.651
83    P        -0.603  -0.603  -0.603  -0.465  -0.465  -0.465  -0.603  -0.603  -0.603
84    L        -0.603  -0.603  -0.603  -0.919  -0.919  -0.919  -0.603  -0.603  -0.603
85    P         1.651   1.651   1.651   1.719   1.719   1.719   1.651   1.651   1.651
86    R        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
87    H         1.651   1.651   1.651   1.844   1.844   1.844   1.651   1.651   1.651
88    A        -0.603  -0.603  -0.603  -0.456  -0.456  -0.456  -0.603  -0.603  -0.603
89    H        -0.603  -0.603  -0.603  -0.375  -0.375  -0.375  -0.603  -0.603  -0.603
90    L        -0.603  -0.603  -0.603  -0.929  -0.929  -0.929  -0.603  -0.603  -0.603
91    F        -0.603  -0.603  -0.603  -0.850  -0.850  -0.850  -0.603  -0.603  -0.603
92    Q        -0.603  -0.603  -0.603  -0.411  -0.411  -0.411  -0.603  -0.603  -0.603
93    K        -0.603  -0.603  -0.603  -0.547  -0.547  -0.547  -0.603  -0.603  -0.603
94    H        -0.603  -0.603  -0.603  -0.296  -0.296  -0.296  -0.603  -0.603  -0.603
95    Y        -0.603  -0.603  -0.603  -0.384  -0.384  -0.384  -0.603  -0.603  -0.603
96    H        -0.603  -0.603  -0.603  -0.456  -0.456  -0.456  -0.603  -0.603  -0.603
97    F        -0.603  -0.603  -0.603  -0.456  -0.456  -0.456  -0.603  -0.603  -0.603
98    L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
99    L        -0.603  -0.603  -0.603  -0.939  -0.939  -0.939  -0.603  -0.603  -0.603
100   T        -0.603  -0.603  -0.603  -0.705  -0.705  -0.705  -0.603  -0.603  -0.603
101   H        -0.603  -0.603  -0.603  -0.349  -0.349  -0.349  -0.603  -0.603  -0.603
102   W         1.651   1.651   1.651   2.002   2.002   2.002   1.651   1.651   1.651
103   P         1.651   1.651   1.651   1.719   1.719   1.719   1.651   1.651   1.651
104   F        -0.603  -0.603  -0.603  -0.322  -0.322  -0.322  -0.603  -0.603  -0.603
105   E         1.651   1.651   1.651   1.694   1.694   1.694   1.651   1.651   1.651
106   N        -0.603  -0.603  -0.603  -0.322  -0.322  -0.322  -0.603  -0.603  -0.603
107   H        -0.603  -0.603  -0.603  -0.331  -0.331  -0.331  -0.603  -0.603  -0.603
108   R        -0.603  -0.603  -0.603  -0.402  -0.402  -0.402  -0.603  -0.603  -0.603
109   D        -0.603  -0.603  -0.603  -0.565  -0.565  -0.565  -0.603  -0.603  -0.603
110   L        -0.603  -0.603  -0.603  -0.929  -0.929  -0.929  -0.603  -0.603  -0.603
111   V        -0.603  -0.603  -0.603  -0.850  -0.850  -0.850  -0.603  -0.603  -0.603
112   D        -0.603  -0.603  -0.603  -0.483  -0.483  -0.483  -0.603  -0.603  -0.603
113   S        -0.603  -0.603  -0.603  -0.375  -0.375  -0.375  -0.603  -0.603  -0.603
114   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   G        -0.603  -0.603  -0.603  -0.287  -0.287  -0.287  -0.603  -0.603  -0.603
120   K        -0.603  -0.603  -0.603  -0.593  -0.593  -0.593  -0.603  -0.603  -0.603
121   L        -0.603  -0.603  -0.603  -0.919  -0.919  -0.919  -0.603  -0.603  -0.603
122   N         1.651   1.651   1.651   1.656   1.656   1.656   1.651   1.651   1.651
123   S        -0.603  -0.603  -0.603  -1.029  -1.029  -1.029  -0.603  -0.603  -0.603
124   T         1.651   1.651   1.651   1.618   1.618   1.618   1.651   1.651   1.651
125   S         1.651   1.651   1.651   1.580   1.580   1.580   1.651   1.651   1.651
126   S        -0.603  -0.603  -0.603  -0.519  -0.519  -0.519  -0.603  -0.603  -0.603
127   R        -0.603  -0.603  -0.603  -0.565  -0.565  -0.565  -0.603  -0.603  -0.603
128   S        -0.603  -0.603  -0.603  -0.611  -0.611  -0.611  -0.603  -0.603  -0.603
129   V        -0.603  -0.603  -0.603  -0.850  -0.850  -0.850  -0.603  -0.603  -0.603
130   W         1.651   1.651   1.651   2.002   2.002   2.002   1.651   1.651   1.651
131   L        -0.603  -0.603  -0.603  -1.029  -1.029  -1.029  -0.603  -0.603  -0.603
132   K        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
133   A        -0.603  -0.603  -0.603  -0.565  -0.565  -0.565  -0.603  -0.603  -0.603
134   D        -0.603  -0.603  -0.603  -0.510  -0.510  -0.510  -0.603  -0.603  -0.603
135   W        -0.603  -0.603  -0.603  -0.420  -0.420  -0.420  -0.603  -0.603  -0.603
136   I        -0.603  -0.603  -0.603  -0.474  -0.474  -0.474  -0.603  -0.603  -0.603
137   T        -0.603  -0.603  -0.603  -0.593  -0.593  -0.593  -0.603  -0.603  -0.603
138   L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   F         1.651   1.651   1.651   1.807   1.807   1.807   1.651   1.651   1.651
144   N         1.651   1.651   1.651   1.656   1.656   1.656   1.651   1.651   1.651
145   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   K        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
147   N        -0.603  -0.603  -0.603  -0.456  -0.456  -0.456  -0.603  -0.603  -0.603
148   P        -0.603  -0.603  -0.603  -0.630  -0.630  -0.630  -0.603  -0.603  -0.603
149   W         1.651   1.651   1.651   2.002   2.002   2.002   1.651   1.651   1.651
150   V        -0.603  -0.603  -0.603  -0.850  -0.850  -0.850  -0.603  -0.603  -0.603
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   Q         1.651   1.651   1.651   1.832   1.832   1.832   1.651   1.651   1.651
157   T         1.651   1.651   1.651   1.618   1.618   1.618   1.651   1.651   1.651
158   P         1.651   1.651   1.651   1.719   1.719   1.719   1.651   1.651   1.651
159   P        -0.603  -0.603  -0.603  -0.547  -0.547  -0.547  -0.603  -0.603  -0.603
160   S        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
161   L        -0.603  -0.603  -0.603  -0.939  -0.939  -0.939  -0.603  -0.603  -0.603
162   M        -0.603  -0.603  -0.603  -0.677  -0.677  -0.677  -0.603  -0.603  -0.603
163   R        -0.603  -0.603  -0.603  -0.501  -0.501  -0.501  -0.603  -0.603  -0.603
164   L        -0.603  -0.603  -0.603  -1.060  -1.060  -1.060  -0.603  -0.603  -0.603
165   S        -0.603  -0.603  -0.603  -0.565  -0.565  -0.565  -0.603  -0.603  -0.603
166   G        -0.603  -0.603  -0.603  -0.331  -0.331  -0.331  -0.603  -0.603  -0.603
167   T         1.651   1.651   1.651   1.618   1.618   1.618   1.651   1.651   1.651
168   D        -0.603  -0.603  -0.603  -0.287  -0.287  -0.287  -0.603  -0.603  -0.603
169   L        -0.603  -0.603  -0.603  -0.929  -0.929  -0.929  -0.603  -0.603  -0.603
170   D         1.651   1.651   1.651   1.769   1.769   1.769   1.651   1.651   1.651
171   T        -0.603  -0.603  -0.603  -0.393  -0.393  -0.393  -0.603  -0.603  -0.603
172   F        -0.603  -0.603  -0.603  -0.850  -0.850  -0.850  -0.603  -0.603  -0.603
173   T        -0.603  -0.603  -0.603  -0.492  -0.492  -0.492  -0.603  -0.603  -0.603
174   P        -0.603  -0.603  -0.603  -0.602  -0.602  -0.602  -0.603  -0.603  -0.603
175   E        -0.603  -0.603  -0.603  -0.593  -0.593  -0.593  -0.603  -0.603  -0.603
176   R        -0.603  -0.603  -0.603  -0.411  -0.411  -0.411  -0.603  -0.603  -0.603
177   I         1.651   1.651   1.651   1.707   1.707   1.707   1.651   1.651   1.651
178   F        -0.603  -0.603  -0.603  -0.510  -0.510  -0.510  -0.603  -0.603  -0.603
179   L        -0.603  -0.603  -0.603  -0.939  -0.939  -0.939  -0.603  -0.603  -0.603
180   I        -0.603  -0.603  -0.603  -0.447  -0.447  -0.447  -0.603  -0.603  -0.603
181   N        -0.603  -0.603  -0.603  -0.969  -0.969  -0.969  -0.603  -0.603  -0.603
182   S        -0.603  -0.603  -0.603  -0.593  -0.593  -0.593  -0.603  -0.603  -0.603
183   L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
184   G        -0.603  -0.603  -0.603  -0.322  -0.322  -0.322  -0.603  -0.603  -0.603
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   N        -0.603  -0.603  -0.603  -0.565  -0.565  -0.565  -0.603  -0.603  -0.603
198   H         1.651   1.651   1.651   1.844   1.844   1.844   1.651   1.651   1.651
199   Y         1.651   1.651   1.651   1.881   1.881   1.881   1.651   1.651   1.651
200   K        -0.603  -0.603  -0.603  -0.510  -0.510  -0.510  -0.603  -0.603  -0.603
201   F         1.651   1.651   1.651   1.807   1.807   1.807   1.651   1.651   1.651
202   L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
203   I        -0.603  -0.603  -0.603  -0.639  -0.639  -0.639  -0.603  -0.603  -0.603
204   A        -0.603  -0.603  -0.603  -0.593  -0.593  -0.593  -0.603  -0.603  -0.603
205   N         1.651   1.651   1.651   1.656   1.656   1.656   1.651   1.651   1.651
206   S        -0.603  -0.603  -0.603  -0.602  -0.602  -0.602  -0.603  -0.603  -0.603
207   H        -0.603  -0.603  -0.603  -0.537  -0.537  -0.537  -0.603  -0.603  -0.603
208   L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
209   S        -0.603  -0.603  -0.603  -0.331  -0.331  -0.331  -0.603  -0.603  -0.603
210   Y        -0.603  -0.603  -0.603  -0.402  -0.402  -0.402  -0.603  -0.603  -0.603
211   N        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
212   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   K         1.651   1.651   1.651   1.542   1.542   1.542   1.651   1.651   1.651
214   K         1.651   1.651   1.651   1.542   1.542   1.542   1.651   1.651   1.651
215   Y        -0.603  -0.603  -0.603  -0.791  -0.791  -0.791  -0.603  -0.603  -0.603
216   P        -0.603  -0.603  -0.603  -0.420  -0.420  -0.420  -0.603  -0.603  -0.603
217   S        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
218   P         1.651   1.651   1.651   1.719   1.719   1.719   1.651   1.651   1.651
219   G        -0.603  -0.603  -0.603  -0.331  -0.331  -0.331  -0.603  -0.603  -0.603
220   V         1.651   1.651   1.651   1.807   1.807   1.807   1.651   1.651   1.651
221   Q        -0.603  -0.603  -0.603  -0.438  -0.438  -0.438  -0.603  -0.603  -0.603
222   I         1.651   1.651   1.651   1.707   1.707   1.707   1.651   1.651   1.651
223   P        -0.603  -0.603  -0.603  -0.322  -0.322  -0.322  -0.603  -0.603  -0.603
224   V        -0.603  -0.603  -0.603  -0.218  -0.218  -0.218  -0.603  -0.603  -0.603
225   R        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
226   N        -0.603  -0.603  -0.603  -0.547  -0.547  -0.547  -0.603  -0.603  -0.603
227   A        -0.603  -0.603  -0.603  -0.483  -0.483  -0.483  -0.603  -0.603  -0.603
228   L        -0.603  -0.603  -0.603  -0.724  -0.724  -0.724  -0.603  -0.603  -0.603
229   G        -0.603  -0.603  -0.603  -0.261  -0.261  -0.261  -0.603  -0.603  -0.603
230   E        -0.603  -0.603  -0.603  -0.483  -0.483  -0.483  -0.603  -0.603  -0.603
231   V        -0.603  -0.603  -0.603  -0.447  -0.447  -0.447  -0.603  -0.603  -0.603
232   S        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
233   P        -0.603  -0.603  -0.603  -0.465  -0.465  -0.465  -0.603  -0.603  -0.603
234   A        -0.603  -0.603  -0.603  -0.528  -0.528  -0.528  -0.603  -0.603  -0.603
235   K        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
236   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   I         1.651   1.651   1.651   1.707   1.707   1.707   1.651   1.651   1.651
238   A        -0.603  -0.603  -0.603  -0.483  -0.483  -0.483  -0.603  -0.603  -0.603
239   Q        -0.603  -0.603  -0.603  -0.465  -0.465  -0.465  -0.603  -0.603  -0.603
240   L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
241   F         1.651   1.651   1.651   1.807   1.807   1.807   1.651   1.651   1.651
242   A        -0.603  -0.603  -0.603  -0.649  -0.649  -0.649  -0.603  -0.603  -0.603
243   R        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
244   Q        -0.603  -0.603  -0.603  -0.547  -0.547  -0.547  -0.603  -0.603  -0.603
245   L        -0.603  -0.603  -0.603  -0.850  -0.850  -0.850  -0.603  -0.603  -0.603
246   S        -0.603  -0.603  -0.603  -0.734  -0.734  -0.734  -0.603  -0.603  -0.603
247   H        -0.603  -0.603  -0.603  -0.820  -0.820  -0.820  -0.603  -0.603  -0.603
248   I         1.651   1.651   1.651   1.707   1.707   1.707   1.651   1.651   1.651
249   Y        -0.603  -0.603  -0.603  -0.483  -0.483  -0.483  -0.603  -0.603  -0.603
250   K        -0.603  -0.603  -0.603  -0.593  -0.593  -0.593  -0.603  -0.603  -0.603
251   S        -0.603  -0.603  -0.603  -1.029  -1.029  -1.029  -0.603  -0.603  -0.603
252   L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
253   F        -0.603  -0.603  -0.603  -0.322  -0.322  -0.322  -0.603  -0.603  -0.603
254   I        -0.603  -0.603  -0.603  -0.611  -0.611  -0.611  -0.603  -0.603  -0.603
255   E        -0.603  -0.603  -0.603  -0.438  -0.438  -0.438  -0.603  -0.603  -0.603
256   N         1.651   1.651   1.651   1.656   1.656   1.656   1.651   1.651   1.651
257   P         1.651   1.651   1.651   1.719   1.719   1.719   1.651   1.651   1.651
258   P        -0.603  -0.603  -0.603  -0.438  -0.438  -0.438  -0.603  -0.603  -0.603
259   L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
260   S        -0.603  -0.603  -0.603  -0.677  -0.677  -0.677  -0.603  -0.603  -0.603
261   P        -0.603  -0.603  -0.603  -0.602  -0.602  -0.602  -0.603  -0.603  -0.603
262   E        -0.603  -0.603  -0.603  -0.483  -0.483  -0.483  -0.603  -0.603  -0.603
263   N        -0.603  -0.603  -0.603  -0.565  -0.565  -0.565  -0.603  -0.603  -0.603
264   E         1.651   1.651   1.651   1.694   1.694   1.694   1.651   1.651   1.651
265   L        -0.603  -0.603  -0.603  -1.029  -1.029  -1.029  -0.603  -0.603  -0.603
266   A        -0.603  -0.603  -0.603  -0.528  -0.528  -0.528  -0.603  -0.603  -0.603
267   L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
268   T         1.651   1.651   1.651   1.618   1.618   1.618   1.651   1.651   1.651
269   A        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
270   V        -0.603  -0.603  -0.603  -0.447  -0.447  -0.447  -0.603  -0.603  -0.603
271   F        -0.603  -0.603  -0.603  -0.375  -0.375  -0.375  -0.603  -0.603  -0.603
272   Y        -0.603  -0.603  -0.603  -0.429  -0.429  -0.429  -0.603  -0.603  -0.603
273   D         1.651   1.651   1.651   1.769   1.769   1.769   1.651   1.651   1.651
274   E        -0.603  -0.603  -0.603  -0.519  -0.519  -0.519  -0.603  -0.603  -0.603
275   T        -0.603  -0.603  -0.603  -0.537  -0.537  -0.537  -0.603  -0.603  -0.603
276   V        -0.603  -0.603  -0.603  -0.850  -0.850  -0.850  -0.603  -0.603  -0.603
277   E        -0.603  -0.603  -0.603  -0.565  -0.565  -0.565  -0.603  -0.603  -0.603
278   R         1.651   1.651   1.651   1.732   1.732   1.732   1.651   1.651   1.651
279   R         1.651   1.651   1.651   1.732   1.732   1.732   1.651   1.651   1.651
280   L        -0.603  -0.603  -0.603  -0.999  -0.999  -0.999  -0.603  -0.603  -0.603
281   R        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
282   R         1.651   1.651   1.651   1.732   1.732   1.732   1.651   1.651   1.651
283   L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
284   Y         1.651   1.651   1.651   1.881   1.881   1.881   1.651   1.651   1.651
285   M        -0.603  -0.603  -0.603  -0.402  -0.402  -0.402  -0.603  -0.603  -0.603
286   R        -0.603  -0.603  -0.603  -0.537  -0.537  -0.537  -0.603  -0.603  -0.603
287   A        -0.603  -0.603  -0.603  -0.456  -0.456  -0.456  -0.603  -0.603  -0.603
288   C        -0.603  -0.603  -0.603  -0.252  -0.252  -0.252  -0.603  -0.603  -0.603
289   A        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
290   R         1.651   1.651   1.651   1.732   1.732   1.732   1.651   1.651   1.651
291   A        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
292   Y         1.651   1.651   1.651   1.881   1.881   1.881   1.651   1.651   1.651
293   T        -0.603  -0.603  -0.603  -0.999  -0.999  -0.999  -0.603  -0.603  -0.603
294   T        -0.603  -0.603  -0.603  -0.510  -0.510  -0.510  -0.603  -0.603  -0.603
295   T        -0.603  -0.603  -0.603  -0.705  -0.705  -0.705  -0.603  -0.603  -0.603
296   N        -0.603  -0.603  -0.603  -0.510  -0.510  -0.510  -0.603  -0.603  -0.603
297   A        -0.603  -0.603  -0.603  -0.340  -0.340  -0.340  -0.603  -0.603  -0.603
298   D        -0.603  -0.603  -0.603  -0.593  -0.593  -0.593  -0.603  -0.603  -0.603
299   S        -0.603  -0.603  -0.603  -0.537  -0.537  -0.537  -0.603  -0.603  -0.603
300   T        -0.603  -0.603  -0.603  -0.593  -0.593  -0.593  -0.603  -0.603  -0.603
301   T        -0.603  -0.603  -0.603  -0.583  -0.583  -0.583  -0.603  -0.603  -0.603
302   E        -0.603  -0.603  -0.603  -0.621  -0.621  -0.621  -0.603  -0.603  -0.603
303   P        -0.603  -0.603  -0.603  -0.519  -0.519  -0.519  -0.603  -0.603  -0.603
304   L         1.651   1.651   1.651   1.144   1.144   1.144   1.651   1.651   1.651
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   M        -0.603  -0.603  -0.603  -0.677  -0.677  -0.677  -0.603  -0.603  -0.603
321   F        -0.603  -0.603  -0.603  -0.456  -0.456  -0.456  -0.603  -0.603  -0.603
322   H        -0.603  -0.603  -0.603  -0.429  -0.429  -0.429  -0.603  -0.603  -0.603
323   C        -0.603  -0.603  -0.603  -0.252  -0.252  -0.252  -0.603  -0.603  -0.603
324   T        -0.603  -0.603  -0.603  -0.999  -0.999  -0.999  -0.603  -0.603  -0.603
325   R        -0.603  -0.603  -0.603  -0.510  -0.510  -0.510  -0.603  -0.603  -0.603
326   W        -0.603  -0.603  -0.603  -0.313  -0.313  -0.313  -0.603  -0.603  -0.603
327   E         1.651   1.651   1.651   1.694   1.694   1.694   1.651   1.651   1.651
328   V        -0.603  -0.603  -0.603  -0.349  -0.349  -0.349  -0.603  -0.603  -0.603
329   D        -0.603  -0.603  -0.603  -0.510  -0.510  -0.510  -0.603  -0.603  -0.603
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12393
Output conservation file - output/Q12393
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
