1     M         2.427   2.454   2.567   2.754   2.799   2.997   2.885   2.940   3.159
2     N        -0.293  -0.273  -0.294  -0.179  -0.161  -0.164  -0.406  -0.391  -0.394
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     D         0.288   0.310   0.311   0.243   0.273   0.292  -0.018   0.012   0.026
10    I        -0.031  -0.100  -0.179  -0.213  -0.313  -0.495  -0.018  -0.114  -0.218
11    K         0.391   0.379   0.348   0.431   0.404   0.364   0.175   0.144   0.096
12    Q        -0.715  -0.719  -0.759  -0.403  -0.408  -0.468  -0.599  -0.604  -0.633
13    L         0.391   0.453   0.387   0.077   0.169   0.085   0.175   0.280   0.170
14    L         0.972   0.973   1.066   0.423   0.413   0.559   0.562   0.552   0.687
15    W         1.553   1.467   1.433   1.879   1.750   1.687   1.724   1.569   1.476
16    N         0.731   0.667   0.544   0.995   0.907   0.745   0.756   0.654   0.446
17    G         1.553   1.467   1.433   1.826   1.708   1.680   1.724   1.569   1.476
18    E         0.391   0.371   0.344   0.320   0.276   0.255   0.175   0.133   0.092
19    L         0.391   0.331   0.349   0.001  -0.070  -0.082   0.175   0.095   0.103
20    N         0.731   0.662   0.537   0.935   0.841   0.642   0.756   0.647   0.435
21    V         1.553   1.467   1.433   1.692   1.575   1.546   1.724   1.569   1.476
22    L        -1.296  -1.316  -1.273  -1.070  -1.104  -1.045  -0.986  -1.004  -0.937
23    V         0.731   0.655   0.541   0.673   0.573   0.392   0.756   0.636   0.441
24    S        -0.411  -0.429  -0.402  -0.675  -0.706  -0.652  -0.529  -0.552  -0.515
25    I         0.403   0.422   0.374   0.104   0.129   0.035   0.229   0.261   0.163
26    D         0.212   0.207   0.251   0.061   0.053   0.095  -0.079  -0.091  -0.041
27    P         0.212   0.237   0.260   0.038   0.080   0.088  -0.079  -0.040  -0.026
28    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    M         1.229   1.284   1.250   1.196   1.279   1.228   1.107   1.213   1.093
32    K         0.403   0.479   0.404   0.429   0.554   0.419   0.229   0.355   0.212
33    G        -0.293  -0.344  -0.324  -0.198  -0.267  -0.229  -0.406  -0.465  -0.428
34    S        -1.296  -1.327  -1.292  -1.509  -1.587  -1.510  -0.986  -1.013  -0.954
35    P        -0.293  -0.311  -0.315  -0.220  -0.242  -0.244  -0.406  -0.422  -0.418
36    R        -0.874  -0.867  -0.860  -0.806  -0.791  -0.788  -0.793  -0.782  -0.751
37    E        -1.718  -1.718  -1.661  -1.342  -1.325  -1.249  -1.180  -1.180  -1.101
38    I        -0.898  -0.906  -0.864  -0.956  -0.957  -0.899  -0.803  -0.811  -0.749
39    A        -0.874  -0.846  -0.840  -0.893  -0.830  -0.855  -0.793  -0.763  -0.732
40    V        -1.296  -1.327  -1.292  -1.064  -1.128  -1.068  -0.986  -1.013  -0.954
41    L        -0.293  -0.281  -0.296  -0.300  -0.307  -0.328  -0.406  -0.400  -0.396
42    R        -0.715  -0.769  -0.799  -0.663  -0.724  -0.725  -0.599  -0.660  -0.679
43    I         0.731   0.795   0.576   0.633   0.738   0.389   0.756   0.861   0.499
44    R        -0.874  -0.898  -0.867  -0.675  -0.707  -0.657  -0.793  -0.813  -0.758
45    V         0.731   0.687   0.563   0.754   0.669   0.445   0.756   0.684   0.477
46    P         0.731   0.803   0.584   0.894   1.001   0.661   0.756   0.875   0.513
47    R         1.553   1.467   1.433   1.869   1.755   1.723   1.724   1.569   1.476
48    E        -0.293  -0.322  -0.318  -0.158  -0.187  -0.174  -0.406  -0.432  -0.417
49    T         1.152   1.118   1.144   1.023   0.955   0.982   0.950   0.870   0.862
50    Y        -0.031  -0.100  -0.179   0.268   0.144   0.029  -0.018  -0.114  -0.218
51    L         0.288   0.290   0.309  -0.082  -0.098  -0.081  -0.018  -0.011   0.025
52    V         0.129   0.136   0.214   0.046   0.042   0.164  -0.212  -0.204  -0.102
53    N        -0.874  -0.848  -0.838  -1.191  -1.167  -1.127  -0.793  -0.766  -0.730
54    Y        -0.031  -0.061  -0.166   0.260   0.229   0.040  -0.018  -0.061  -0.200
55    M        -0.874  -0.914  -0.858  -0.807  -0.849  -0.762  -0.793  -0.829  -0.749
56    P         1.553   1.467   1.433   1.784   1.679   1.658   1.724   1.569   1.476
57    L        -0.874  -0.833  -0.846  -0.941  -0.878  -0.880  -0.793  -0.752  -0.738
58    I         0.391   0.445   0.387   0.116   0.205   0.065   0.175   0.256   0.164
59    W        -1.296  -1.327  -1.292  -1.349  -1.381  -1.325  -0.986  -1.013  -0.954
60    N        -0.715  -0.754  -0.762  -0.351  -0.410  -0.418  -0.599  -0.643  -0.637
61    K        -0.453  -0.439  -0.396  -0.509  -0.482  -0.438  -0.599  -0.583  -0.516
62    I         0.129   0.136   0.214  -0.422  -0.429  -0.325  -0.212  -0.204  -0.102
63    K        -0.874  -0.869  -0.854  -0.598  -0.596  -0.552  -0.793  -0.785  -0.745
64    S        -0.715  -0.736  -0.763  -0.588  -0.626  -0.685  -0.599  -0.623  -0.638
65    F        -1.296  -1.312  -1.267  -1.068  -1.096  -1.029  -0.986  -1.000  -0.932
66    L        -0.405  -0.388  -0.372  -0.950  -0.932  -0.904  -0.540  -0.520  -0.486
67    S        -1.001  -1.002  -0.930  -1.101  -1.104  -1.000  -0.909  -0.909  -0.817
68    F        -1.001  -1.002  -0.930  -1.022  -1.031  -0.917  -0.909  -0.909  -0.817
69    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    L         0.403   0.411   0.349   0.057   0.066  -0.067   0.229   0.242   0.121
72    T         0.403   0.422   0.374   0.505   0.538   0.446   0.229   0.261   0.163
73    D        -0.526  -0.521  -0.446  -0.759  -0.774  -0.645  -0.672  -0.666  -0.569
74    S         0.180   0.184   0.246  -0.191  -0.191  -0.115  -0.150  -0.144  -0.060
75    E        -0.405  -0.387  -0.364  -0.595  -0.584  -0.532  -0.540  -0.518  -0.477
76    K        -0.898  -0.898  -0.876  -0.816  -0.823  -0.787  -0.803  -0.802  -0.762
77    Y        -0.898  -0.924  -0.892  -0.707  -0.746  -0.689  -0.803  -0.830  -0.779
78    F        -0.898  -0.896  -0.859  -0.756  -0.741  -0.691  -0.803  -0.800  -0.744
79    W         2.427   2.454   2.567   2.753   2.799   2.996   2.885   2.940   3.159
80    F         0.272   0.258   0.277  -0.030  -0.050  -0.002  -0.013  -0.032  -0.012
81    E         0.579   0.535   0.451   0.755   0.687   0.532   0.514   0.446   0.290
82    H         0.579   0.619   0.483   0.895   0.959   0.769   0.514   0.580   0.343
83    N        -0.405  -0.414  -0.377  -0.421  -0.434  -0.381  -0.540  -0.548  -0.491
84    K        -0.898  -0.886  -0.861  -0.707  -0.691  -0.652  -0.803  -0.789  -0.746
85    T         0.579   0.559   0.446   0.624   0.586   0.382   0.514   0.483   0.282
86    P         1.467   1.452   1.379   1.605   1.584   1.465   1.568   1.540   1.366
87    I         0.272   0.291   0.301  -0.313  -0.286  -0.292  -0.013   0.016   0.022
88    P         0.950   0.965   1.061   0.719   0.740   0.888   0.514   0.535   0.674
89    W         2.427   2.454   2.567   2.753   2.799   2.996   2.885   2.940   3.159
90    N        -0.715  -0.764  -0.784  -0.454  -0.531  -0.552  -0.599  -0.655  -0.662
91    Y        -0.874  -0.911  -0.869  -0.976  -1.010  -0.945  -0.793  -0.826  -0.759
92    P         1.553   1.467   1.433   1.720   1.598   1.550   1.724   1.569   1.476
93    V        -0.293  -0.300  -0.295  -0.379  -0.406  -0.372  -0.406  -0.417  -0.395
94    G         2.427   2.454   2.567   2.628   2.667   2.866   2.885   2.940   3.159
95    V         0.391   0.355   0.346   0.174   0.077   0.061   0.175   0.111   0.095
96    L         1.553   1.467   1.433   1.357   1.231   1.179   1.724   1.569   1.476
97    F         0.972   0.983   1.071   0.901   0.917   1.052   0.562   0.574   0.698
98    D         2.427   2.454   2.567   2.568   2.610   2.803   2.885   2.940   3.159
99    C        -0.715  -0.681  -0.756  -0.802  -0.760  -0.848  -0.599  -0.556  -0.630
100   L         1.553   1.558   1.448   1.397   1.404   1.269   1.724   1.735   1.507
101   A        -1.296  -1.259  -1.266  -0.811  -0.770  -0.743  -0.986  -0.949  -0.931
102   G        -0.293  -0.244  -0.292  -0.430  -0.330  -0.417  -0.406  -0.336  -0.383
103   K        -1.296  -1.318  -1.269  -1.267  -1.333  -1.229  -0.986  -1.006  -0.934
104   S        -0.293  -0.292  -0.300  -0.260  -0.268  -0.238  -0.406  -0.410  -0.399
105   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   F        -0.526  -0.516  -0.446  -0.763  -0.736  -0.649  -0.672  -0.660  -0.569
108   T         0.950   0.968   1.063   0.622   0.639   0.787   0.514   0.542   0.679
109   T         0.212   0.194   0.254   0.154   0.114   0.205  -0.079  -0.112  -0.036
110   S        -0.874  -0.830  -0.851  -1.121  -1.033  -1.117  -0.793  -0.750  -0.743
111   F        -1.296  -1.259  -1.266  -1.169  -1.097  -1.132  -0.986  -0.949  -0.931
112   E        -0.874  -0.836  -0.849  -0.697  -0.648  -0.645  -0.793  -0.755  -0.741
113   N        -0.293  -0.329  -0.296  -0.285  -0.337  -0.290  -0.406  -0.442  -0.394
114   Q        -0.293  -0.257  -0.293  -0.026   0.030   0.001  -0.406  -0.355  -0.390
115   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   V        -1.390  -1.388  -1.327  -1.159  -1.178  -1.060  -1.067  -1.065  -0.983
119   L        -0.293  -0.289  -0.303  -0.661  -0.661  -0.683  -0.406  -0.408  -0.403
120   T        -1.718  -1.718  -1.661  -1.377  -1.364  -1.285  -1.180  -1.180  -1.101
121   F        -1.718  -1.718  -1.661  -1.613  -1.645  -1.530  -1.180  -1.180  -1.101
122   L         1.152   1.118   1.144   1.170   1.082   1.062   0.950   0.870   0.862
123   R         0.129   0.142   0.201   0.060   0.074   0.166  -0.212  -0.193  -0.122
124   I         0.972   0.998   1.074   0.286   0.329   0.420   0.562   0.608   0.705
125   H        -1.296  -1.259  -1.266  -0.974  -0.907  -0.927  -0.986  -0.949  -0.931
126   L         0.731   0.687   0.563   0.613   0.537   0.382   0.756   0.684   0.477
127   V        -0.874  -0.888  -0.855  -0.687  -0.719  -0.638  -0.793  -0.805  -0.747
128   M        -1.718  -1.718  -1.661  -1.203  -1.203  -1.106  -1.180  -1.180  -1.101
129   G        -0.715  -0.732  -0.767  -0.476  -0.511  -0.571  -0.599  -0.619  -0.643
130   D        -0.405  -0.366  -0.355  -0.396  -0.333  -0.317  -0.540  -0.495  -0.467
131   S        -1.296  -1.295  -1.274  -1.313  -1.303  -1.304  -0.986  -0.985  -0.938
132   L         0.391   0.405   0.359   0.437   0.463   0.356   0.175   0.197   0.115
133   P         2.427   2.454   2.567   2.554   2.597   2.789   2.885   2.940   3.159
134   P        -0.453  -0.487  -0.396  -0.661  -0.707  -0.582  -0.599  -0.630  -0.517
135   T        -0.874  -0.844  -0.840  -0.694  -0.658  -0.634  -0.793  -0.762  -0.733
136   I        -1.296  -1.303  -1.278  -1.429  -1.475  -1.401  -0.986  -0.992  -0.941
137   I         0.391   0.403   0.361  -0.056  -0.063  -0.152   0.175   0.176   0.117
138   P         0.129   0.137   0.205  -0.374  -0.370  -0.303  -0.212  -0.201  -0.115
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   I        -0.874  -0.886  -0.855  -1.034  -1.041  -1.019  -0.793  -0.803  -0.746
150   A        -0.293  -0.260  -0.277  -0.437  -0.386  -0.388  -0.406  -0.357  -0.370
151   S        -0.874  -0.891  -0.847  -0.791  -0.816  -0.751  -0.793  -0.808  -0.739
152   S        -0.453  -0.444  -0.399  -0.427  -0.423  -0.348  -0.599  -0.588  -0.519
153   K        -0.874  -0.852  -0.842  -0.757  -0.723  -0.718  -0.793  -0.769  -0.734
154   T        -0.874  -0.901  -0.860  -0.709  -0.741  -0.663  -0.793  -0.816  -0.751
155   Q         0.288   0.326   0.313   0.227   0.276   0.253  -0.018   0.028   0.029
156   A        -0.715  -0.662  -0.735  -0.739  -0.678  -0.748  -0.599  -0.534  -0.606
157   E        -0.293  -0.259  -0.288  -0.196  -0.145  -0.176  -0.406  -0.364  -0.384
158   K        -0.874  -0.833  -0.846  -0.724  -0.673  -0.664  -0.793  -0.752  -0.738
159   F        -0.874  -0.830  -0.851  -0.718  -0.641  -0.683  -0.793  -0.750  -0.743
160   W        -0.715  -0.659  -0.754  -0.391  -0.287  -0.472  -0.599  -0.531  -0.628
161   F        -0.874  -0.887  -0.844  -0.730  -0.766  -0.694  -0.793  -0.804  -0.736
162   H         0.288   0.290   0.309   0.373   0.392   0.442  -0.018  -0.011   0.025
163   Q         0.731   0.743   0.565   1.094   1.113   0.868   0.756   0.779   0.481
164   W         0.972   0.989   1.075   0.597   0.615   0.756   0.562   0.587   0.706
165   K         2.427   2.454   2.567   2.547   2.594   2.782   2.885   2.940   3.159
166   Q         1.152   1.122   1.153   1.260   1.200   1.233   0.950   0.877   0.882
167   V        -0.293  -0.312  -0.321  -0.231  -0.257  -0.237  -0.406  -0.432  -0.427
168   C         1.553   1.587   1.447   2.005   2.057   1.877   1.724   1.788   1.504
169   F         0.731   0.662   0.537   1.039   0.938   0.756   0.756   0.647   0.435
170   I         0.288   0.235   0.297  -0.100  -0.178  -0.091  -0.018  -0.079   0.008
171   L         0.391   0.401   0.357   0.044   0.053  -0.021   0.175   0.173   0.112
172   N         1.553   1.467   1.433   1.745   1.635   1.590   1.724   1.569   1.476
173   G         2.427   2.454   2.567   2.628   2.667   2.866   2.885   2.940   3.159
174   S         0.391   0.409   0.353   0.290   0.302   0.228   0.175   0.189   0.104
175   S         0.972   0.979   1.067   0.765   0.771   0.916   0.562   0.566   0.689
176   K         0.731   0.662   0.537   0.913   0.818   0.614   0.756   0.647   0.435
177   A        -0.293  -0.253  -0.294  -0.119  -0.050  -0.091  -0.406  -0.347  -0.385
178   I         1.152   1.109   1.146   0.829   0.749   0.776   0.950   0.850   0.866
179   M         1.553   1.587   1.447   1.896   1.951   1.739   1.724   1.788   1.504
180   S        -0.031   0.057  -0.161   0.132   0.257  -0.046  -0.018   0.107  -0.194
181   L         2.427   2.454   2.567   2.193   2.230   2.416   2.885   2.940   3.159
182   S         2.427   2.454   2.567   2.434   2.476   2.665   2.885   2.940   3.159
183   V        -1.296  -1.327  -1.292  -1.343  -1.399  -1.396  -0.986  -1.013  -0.954
184   N        -0.715  -0.679  -0.753  -0.357  -0.297  -0.420  -0.599  -0.554  -0.626
185   E         0.129   0.126   0.198   0.009   0.002   0.108  -0.212  -0.218  -0.125
186   A        -0.293  -0.259  -0.279  -0.273  -0.229  -0.231  -0.406  -0.357  -0.372
187   R        -1.296  -1.316  -1.273  -1.130  -1.160  -1.099  -0.986  -1.004  -0.937
188   K        -0.874  -0.842  -0.836  -0.655  -0.618  -0.581  -0.793  -0.760  -0.729
189   F        -0.874  -0.911  -0.869  -0.908  -0.936  -0.861  -0.793  -0.826  -0.759
190   W         2.427   2.454   2.567   2.751   2.797   2.993   2.885   2.940   3.159
191   G        -1.296  -1.316  -1.273  -1.021  -1.050  -0.977  -0.986  -1.004  -0.937
192   S         0.731   0.743   0.565   0.871   0.889   0.654   0.756   0.779   0.481
193   V         0.129   0.149   0.215  -0.514  -0.485  -0.405  -0.212  -0.183  -0.099
194   I        -0.715  -0.749  -0.769  -0.863  -0.921  -0.965  -0.599  -0.638  -0.645
195   T        -0.715  -0.682  -0.744  -0.681  -0.620  -0.737  -0.599  -0.558  -0.616
196   R         0.972   0.979   1.068   1.000   1.006   1.153   0.562   0.566   0.691
197   N         0.288   0.312   0.316   0.245   0.280   0.319  -0.018   0.015   0.033
198   F        -0.453  -0.438  -0.393  -0.590  -0.547  -0.464  -0.599  -0.582  -0.513
199   Q        -1.296  -1.273  -1.260  -0.965  -0.930  -0.897  -0.986  -0.962  -0.925
200   D        -0.031  -0.081  -0.157   0.174   0.097  -0.030  -0.018  -0.088  -0.188
201   F         1.152   1.171   1.179   1.237   1.270   1.263   0.950   0.981   0.939
202   I        -0.874  -0.911  -0.869  -0.925  -0.956  -0.899  -0.793  -0.826  -0.759
203   E        -1.718  -1.718  -1.661  -1.462  -1.479  -1.374  -1.180  -1.180  -1.101
204   I         0.391   0.436   0.383   0.016   0.091  -0.032   0.175   0.239   0.156
205   S        -1.296  -1.327  -1.292  -1.091  -1.125  -1.084  -0.986  -1.013  -0.954
206   N        -0.715  -0.752  -0.787  -0.576  -0.628  -0.710  -0.599  -0.641  -0.665
207   K         0.731   0.636   0.546   0.971   0.840   0.719   0.756   0.607   0.450
208   I         1.553   1.593   1.451   1.407   1.476   1.235   1.724   1.798   1.512
209   S         0.391   0.442   0.391  -0.114  -0.020  -0.132   0.175   0.264   0.177
210   S        -0.220  -0.160  -0.233  -0.121  -0.023  -0.151  -0.276  -0.193  -0.293
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   S        -0.874  -0.909  -0.861  -0.832  -0.875  -0.797  -0.793  -0.824  -0.752
217   R        -0.293  -0.342  -0.297  -0.175  -0.239  -0.158  -0.406  -0.459  -0.397
218   P        -0.874  -0.843  -0.843  -0.986  -0.949  -0.942  -0.793  -0.761  -0.735
219   R        -0.293  -0.224  -0.291  -0.148  -0.042  -0.135  -0.406  -0.319  -0.388
220   H        -0.874  -0.889  -0.850  -0.598  -0.631  -0.562  -0.793  -0.806  -0.742
221   I         1.152   1.136   1.157   0.712   0.673   0.639   0.950   0.907   0.891
222   P         2.427   2.454   2.567   2.554   2.597   2.789   2.885   2.940   3.159
223   L         0.129   0.123   0.192  -0.430  -0.461  -0.391  -0.212  -0.224  -0.136
224   I        -0.031  -0.016  -0.172   0.174   0.203  -0.049  -0.018   0.006  -0.209
225   I         1.152   1.124   1.147   0.829   0.777   0.779   0.950   0.882   0.870
226   Q        -0.031  -0.016  -0.172   0.402   0.431   0.225  -0.018   0.006  -0.209
227   T        -0.453  -0.452  -0.400  -0.835  -0.845  -0.748  -0.599  -0.595  -0.521
228   S        -0.293  -0.291  -0.297  -0.160  -0.172  -0.173  -0.406  -0.406  -0.398
229   R        -1.296  -1.327  -1.292  -0.895  -0.935  -0.871  -0.986  -1.013  -0.954
230   T        -0.715  -0.699  -0.772  -0.550  -0.531  -0.621  -0.599  -0.577  -0.648
231   S        -0.874  -0.901  -0.856  -0.761  -0.807  -0.723  -0.793  -0.817  -0.748
232   G        -0.898  -0.894  -0.863  -0.834  -0.816  -0.789  -0.803  -0.799  -0.749
233   T        -0.715  -0.735  -0.760  -0.667  -0.675  -0.711  -0.599  -0.622  -0.635
234   F        -0.293  -0.267  -0.293  -0.624  -0.578  -0.638  -0.406  -0.370  -0.391
235   R        -0.031  -0.064  -0.153   0.413   0.362   0.260  -0.018  -0.066  -0.182
236   I        -0.293  -0.273  -0.305  -0.186  -0.161  -0.222  -0.406  -0.380  -0.406
237   S        -0.293  -0.340  -0.304  -0.437  -0.517  -0.462  -0.406  -0.452  -0.399
238   Q        -0.715  -0.772  -0.796  -0.687  -0.771  -0.781  -0.599  -0.664  -0.675
239   P         0.579   0.527   0.464   0.745   0.667   0.570   0.514   0.431   0.313
240   T        -0.405  -0.378  -0.364  -0.491  -0.454  -0.438  -0.540  -0.509  -0.476
241   I        -1.390  -1.392  -1.327  -1.430  -1.424  -1.341  -1.067  -1.068  -0.983
242   S         1.071   1.057   1.116   0.865   0.832   0.914   0.778   0.738   0.799
243   M         1.361   1.415   1.339   1.500   1.581   1.481   1.368   1.470   1.283
244   T         0.403   0.342   0.351   0.431   0.318   0.310   0.229   0.129   0.124
245   G         0.993   1.019   1.091   0.796   0.835   0.933   0.609   0.654   0.742
246   V        -0.411  -0.382  -0.357  -0.405  -0.357  -0.326  -0.529  -0.491  -0.458
247   N        -1.001  -0.995  -0.930  -1.128  -1.166  -1.028  -0.909  -0.902  -0.817
248   P        -0.898  -0.902  -0.860  -0.673  -0.689  -0.617  -0.803  -0.808  -0.746
249   T        -0.031   0.011  -0.140   0.161   0.226  -0.034  -0.018   0.043  -0.164
250   L         0.731   0.636   0.546   0.512   0.356   0.199   0.756   0.607   0.450
251   K        -0.898  -0.859  -0.863  -0.632  -0.579  -0.574  -0.803  -0.759  -0.749
252   D         0.272   0.235   0.299   0.277   0.230   0.327  -0.013  -0.058   0.020
253   I        -0.220  -0.266  -0.284  -0.399  -0.473  -0.513  -0.276  -0.338  -0.362
254   E         0.579   0.582   0.464   0.424   0.425   0.271   0.514   0.520   0.312
255   G        -1.390  -1.388  -1.327  -1.119  -1.100  -1.018  -1.067  -1.065  -0.983
256   D        -0.898  -0.853  -0.855  -1.036  -0.956  -0.985  -0.803  -0.753  -0.740
257   I        -0.898  -0.875  -0.851  -0.587  -0.547  -0.516  -0.803  -0.777  -0.736
258   L         0.579   0.632   0.498   0.369   0.439   0.246   0.514   0.601   0.370
259   D         0.579   0.582   0.464   0.651   0.658   0.438   0.514   0.520   0.312
260   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   E        -0.405  -0.414  -0.372  -0.378  -0.389  -0.326  -0.540  -0.548  -0.486
263   G         0.180   0.162   0.238  -0.152  -0.175  -0.065  -0.150  -0.173  -0.071
264   I        -0.453  -0.429  -0.396  -0.799  -0.751  -0.702  -0.599  -0.575  -0.517
265   N        -0.874  -0.867  -0.860  -0.873  -0.857  -0.835  -0.793  -0.782  -0.751
266   G        -0.031  -0.016  -0.172   0.097   0.119  -0.110  -0.018   0.006  -0.209
267   N        -0.715  -0.751  -0.765  -0.415  -0.463  -0.475  -0.599  -0.640  -0.640
268   D        -0.293  -0.311  -0.304  -0.281  -0.298  -0.300  -0.406  -0.421  -0.405
269   -         0.212   0.269   0.263   0.098   0.199   0.162  -0.079   0.012  -0.020
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -0.526  -0.517  -0.446  -0.901  -0.898  -0.792  -0.672  -0.661  -0.569
272   -        -0.526  -0.517  -0.446  -0.904  -0.884  -0.796  -0.672  -0.661  -0.569
273   V        -0.411  -0.389  -0.371  -0.395  -0.364  -0.337  -0.529  -0.503  -0.476
274   M        -1.296  -1.261  -1.259  -0.897  -0.839  -0.831  -0.986  -0.952  -0.924
275   V        -0.453  -0.429  -0.394  -0.556  -0.516  -0.472  -0.599  -0.575  -0.515
276   I         0.129   0.166   0.226  -0.178  -0.117  -0.045  -0.212  -0.156  -0.082
277   C         0.391   0.318   0.347   0.249   0.151   0.199   0.175   0.072   0.099
278   Q         0.972   0.979   1.068   1.005   1.013   1.159   0.562   0.566   0.691
279   G         2.427   2.454   2.567   2.628   2.667   2.866   2.885   2.940   3.159
280   I         1.553   1.467   1.433   1.457   1.347   1.288   1.724   1.569   1.476
281   E        -0.874  -0.832  -0.843  -0.779  -0.720  -0.721  -0.793  -0.751  -0.735
282   I         0.288   0.288   0.311  -0.017  -0.011   0.043  -0.018  -0.016   0.026
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   P        -0.874  -0.830  -0.839  -0.868  -0.789  -0.826  -0.793  -0.749  -0.731
288   W        -0.874  -0.836  -0.849  -1.098  -1.059  -1.050  -0.793  -0.755  -0.741
289   H        -0.293  -0.276  -0.306  -0.170  -0.142  -0.161  -0.406  -0.382  -0.406
290   M        -1.718  -1.718  -1.661  -1.283  -1.278  -1.189  -1.180  -1.180  -1.101
291   L        -0.453  -0.444  -0.393  -0.749  -0.746  -0.680  -0.599  -0.589  -0.515
292   L         0.972   1.007   1.084   0.286   0.348   0.442   0.562   0.628   0.728
293   Y        -0.874  -0.890  -0.852  -0.825  -0.825  -0.776  -0.793  -0.806  -0.744
294   D         0.129   0.131   0.203   0.009   0.008   0.116  -0.212  -0.212  -0.118
295   L         0.391   0.446   0.367  -0.048   0.032  -0.117   0.175   0.259   0.128
296   Y         0.391   0.449   0.378   0.563   0.661   0.556   0.175   0.273   0.155
297   S        -1.296  -1.295  -1.274  -1.007  -1.005  -0.963  -0.986  -0.985  -0.938
298   K        -0.293  -0.344  -0.324  -0.521  -0.577  -0.531  -0.406  -0.465  -0.428
299   L         0.391   0.318   0.347   0.344   0.233   0.247   0.175   0.072   0.099
300   R        -1.296  -1.327  -1.292  -0.784  -0.815  -0.731  -0.986  -1.013  -0.954
301   S         0.129   0.137   0.205   0.037   0.045   0.157  -0.212  -0.201  -0.115
302   F        -0.293  -0.327  -0.297  -0.693  -0.719  -0.682  -0.406  -0.437  -0.390
303   D         2.427   2.454   2.567   2.568   2.610   2.803   2.885   2.940   3.159
304   G         1.152   1.216   1.210   1.185   1.290   1.263   0.950   1.074   1.008
305   F         1.553   1.558   1.448   1.846   1.863   1.727   1.724   1.735   1.507
306   L         2.427   2.454   2.567   2.193   2.230   2.416   2.885   2.940   3.159
307   Y         0.972   0.972   1.064   0.987   0.987   1.135   0.562   0.551   0.682
308   I         0.731   0.748   0.569   0.586   0.618   0.304   0.756   0.787   0.486
309   T        -0.453  -0.487  -0.392  -0.738  -0.797  -0.657  -0.599  -0.630  -0.513
310   L        -0.031   0.015  -0.136  -0.223  -0.155  -0.400  -0.018   0.049  -0.159
311   V        -0.411  -0.337  -0.359  -0.652  -0.503  -0.599  -0.529  -0.433  -0.460
312   P        -1.001  -0.995  -0.930  -1.000  -0.963  -0.895  -0.909  -0.902  -0.817
313   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   L        -0.715  -0.728  -0.764  -0.986  -1.001  -1.086  -0.599  -0.614  -0.639
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12380
Output conservation file - output/Q12380
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
