1     M         2.129   2.153   2.244   2.349   2.384   2.525   2.436   2.472   2.629
2     S         2.129   2.153   2.244   2.047   2.084   2.219   2.436   2.472   2.629
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    N        -0.005  -0.042   0.038  -0.105  -0.153  -0.042  -0.293  -0.337  -0.231
60    F         0.083  -0.001   0.072   0.173   0.054   0.153  -0.170  -0.282  -0.182
61    G         1.218   1.105   1.100   1.405   1.246   1.247   1.252   1.046   1.002
62    R         2.129   2.153   2.244   2.098   2.124   2.270   2.436   2.472   2.629
63    R         0.841   0.796   0.867   0.548   0.427   0.521   0.541   0.439   0.529
64    T         0.841   0.793   0.864   0.565   0.440   0.528   0.541   0.432   0.522
65    W         1.218   1.105   1.100   1.619   1.471   1.466   1.252   1.046   1.002
66    D         0.727   0.738   0.828   0.409   0.431   0.556   0.304   0.317   0.446
67    R         0.083  -0.001   0.072   0.015  -0.121  -0.009  -0.170  -0.282  -0.182
68    E         0.841   0.934   0.921   0.602   0.762   0.706   0.541   0.718   0.641
69    E         0.374   0.345   0.238   0.364   0.305   0.150   0.304   0.261   0.084
70    Y         2.129   2.153   2.244   2.299   2.337   2.475   2.436   2.472   2.629
71    A         0.374   0.377   0.267   0.506   0.500   0.326   0.304   0.310   0.128
72    E        -0.561  -0.508  -0.522  -0.761  -0.697  -0.691  -0.644  -0.588  -0.576
73    Q        -0.561  -0.508  -0.522  -0.761  -0.723  -0.685  -0.644  -0.588  -0.576
74    A         1.218   1.255   1.123   1.398   1.442   1.290   1.252   1.313   1.046
75    R        -0.561  -0.517  -0.520  -0.802  -0.763  -0.724  -0.644  -0.596  -0.573
76    S        -0.561  -0.509  -0.511  -0.725  -0.636  -0.653  -0.644  -0.585  -0.565
77    G        -0.561  -0.516  -0.518  -0.720  -0.661  -0.659  -0.644  -0.592  -0.572
78    Y        -1.496  -1.487  -1.416  -1.248  -1.289  -1.128  -1.118  -1.107  -1.010
79    D        -1.127  -1.125  -1.044  -1.170  -1.178  -1.048  -0.976  -0.969  -0.865
80    D        -1.496  -1.487  -1.416  -1.419  -1.402  -1.301  -1.118  -1.107  -1.010
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    R        -0.566  -0.590  -0.537  -0.541  -0.607  -0.526  -0.634  -0.664  -0.588
98    S         1.218   1.105   1.100   1.230   1.094   1.083   1.252   1.046   1.002
99    L        -1.029  -1.064  -1.013  -0.903  -0.934  -0.854  -0.881  -0.914  -0.836
100   K        -0.385  -0.360  -0.437  -0.548  -0.506  -0.626  -0.407  -0.373  -0.464
101   A        -0.385  -0.245  -0.426  -0.084   0.143  -0.173  -0.407  -0.223  -0.451
102   T        -0.385  -0.426  -0.440  -0.362  -0.436  -0.479  -0.407  -0.462  -0.468
103   L         1.218   1.105   1.100   1.140   0.979   0.958   1.252   1.046   1.002
104   T        -1.029  -1.018  -0.975  -0.950  -0.924  -0.868  -0.881  -0.870  -0.799
105   P        -1.496  -1.487  -1.416  -1.119  -1.101  -0.997  -1.118  -1.107  -1.010
106   I        -1.029  -0.999  -0.982  -0.954  -0.929  -0.879  -0.881  -0.846  -0.805
107   E         0.083   0.185   0.108   0.018   0.164   0.052  -0.170  -0.024  -0.131
108   L         0.374   0.345   0.238   0.375   0.345   0.178   0.304   0.261   0.084
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   Q        -1.496  -1.487  -1.416  -1.329  -1.312  -1.210  -1.118  -1.107  -1.010
116   A        -1.029  -1.085  -1.008  -0.886  -0.989  -0.870  -0.881  -0.933  -0.831
117   L        -0.455  -0.488  -0.500  -0.600  -0.647  -0.687  -0.523  -0.562  -0.551
118   K        -0.455  -0.488  -0.500  -0.629  -0.674  -0.653  -0.523  -0.562  -0.551
119   S        -0.855  -0.871  -0.878  -0.852  -0.872  -0.914  -0.697  -0.710  -0.697
120   K        -1.007  -1.004  -0.983  -1.199  -1.190  -1.139  -0.871  -0.864  -0.811
121   Y         0.518   0.453   0.309   0.884   0.802   0.598   0.521   0.425   0.194
122   T        -0.455  -0.490  -0.494  -0.379  -0.430  -0.432  -0.523  -0.563  -0.546
123   N        -0.455  -0.455  -0.471  -0.475  -0.466  -0.498  -0.523  -0.513  -0.515
124   Y        -0.054  -0.072   0.011   0.081   0.056   0.176  -0.349  -0.375  -0.265
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   D         0.097   0.088   0.120  -0.052  -0.060  -0.010  -0.175  -0.183  -0.127
127   H        -0.855  -0.819  -0.896  -0.781  -0.748  -0.805  -0.697  -0.653  -0.717
128   L         1.299   1.258   1.168   1.271   1.222   1.109   1.392   1.318   1.131
129   I         0.518   0.571   0.345   0.587   0.658   0.368   0.521   0.600   0.249
130   K        -0.455  -0.423  -0.472  -0.596  -0.528  -0.613  -0.523  -0.478  -0.516
131   G        -1.007  -0.961  -0.992  -0.907  -0.863  -0.858  -0.871  -0.828  -0.819
132   S        -0.455  -0.456  -0.466  -0.562  -0.571  -0.579  -0.523  -0.527  -0.514
133   L        -0.455  -0.506  -0.467  -0.355  -0.411  -0.335  -0.523  -0.577  -0.517
134   K        -0.566  -0.540  -0.511  -0.844  -0.799  -0.777  -0.634  -0.600  -0.556
135   D        -0.005  -0.010   0.040  -0.044  -0.038   0.035  -0.293  -0.296  -0.228
136   L        -0.005   0.009   0.038  -0.137  -0.109  -0.061  -0.293  -0.273  -0.231
137   N         1.117   1.098   1.035   1.011   0.972   0.839   1.071   1.031   0.873
138   K         0.768   0.764   0.840   0.381   0.374   0.493   0.389   0.372   0.472
139   R        -0.566  -0.585  -0.553  -0.502  -0.519  -0.487  -0.634  -0.654  -0.606
140   K        -0.566  -0.562  -0.520  -0.673  -0.657  -0.625  -0.634  -0.626  -0.567
141   L         1.117   1.109   1.043   0.994   0.982   0.882   1.071   1.053   0.890
142   T        -1.007  -0.961  -0.992  -0.940  -0.879  -0.909  -0.871  -0.828  -0.819
143   -         0.727   0.738   0.828   0.570   0.586   0.718   0.304   0.317   0.446
144   -         2.129   2.153   2.244   2.375   2.412   2.552   2.436   2.472   2.629
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   A         0.196   0.187   0.148   0.201   0.184   0.105  -0.001  -0.014  -0.077
149   N        -0.205  -0.282  -0.372  -0.021  -0.128  -0.271  -0.175  -0.270  -0.382
150   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   L        -0.606  -0.602  -0.555  -0.655  -0.637  -0.562  -0.697  -0.688  -0.614
154   S        -0.205  -0.245  -0.370  -0.027  -0.076  -0.249  -0.175  -0.223  -0.380
155   S        -0.455  -0.456  -0.475  -0.389  -0.391  -0.398  -0.523  -0.528  -0.521
156   F        -0.455  -0.449  -0.469  -0.218  -0.216  -0.214  -0.523  -0.521  -0.515
157   K         0.196   0.147   0.155  -0.048  -0.119  -0.098  -0.001  -0.068  -0.059
158   R         0.748   0.756   0.840   0.264   0.268   0.394   0.347   0.356   0.471
159   G         0.919   0.916   0.929   0.901   0.889   0.885   0.695   0.683   0.658
160   K         0.518   0.504   0.323   0.415   0.396   0.148   0.521   0.503   0.215
161   K        -0.606  -0.612  -0.548  -0.728  -0.729  -0.651  -0.697  -0.698  -0.606
162   F         0.196   0.171   0.156   0.339   0.300   0.297  -0.001  -0.044  -0.057
163   G         2.129   2.153   2.244   2.200   2.230   2.374   2.436   2.472   2.629
164   F         1.299   1.290   1.156   1.514   1.513   1.334   1.392   1.373   1.109
165   Y         0.919   0.916   0.929   1.039   1.038   1.034   0.695   0.683   0.658
166   C         2.129   2.153   2.244   2.389   2.427   2.566   2.436   2.472   2.629
167   D        -0.455  -0.442  -0.471  -0.500  -0.471  -0.502  -0.523  -0.494  -0.516
168   I        -0.455  -0.483  -0.465  -0.302  -0.342  -0.317  -0.523  -0.555  -0.513
169   C         2.129   2.153   2.244   2.389   2.427   2.566   2.436   2.472   2.629
170   N         0.748   0.760   0.846   0.494   0.515   0.636   0.347   0.365   0.484
171   L         0.518   0.509   0.328   0.587   0.580   0.344   0.521   0.509   0.223
172   T         0.919   0.916   0.929   0.810   0.800   0.790   0.695   0.683   0.658
173   F         0.518   0.476   0.339   0.794   0.749   0.544   0.521   0.459   0.240
174   K         0.919   0.916   0.929   0.553   0.541   0.543   0.695   0.683   0.658
175   D         2.129   2.153   2.244   2.103   2.140   2.275   2.436   2.472   2.629
176   T        -0.054  -0.033   0.029  -0.254  -0.221  -0.141  -0.349  -0.318  -0.240
177   L         1.299   1.258   1.168   1.272   1.225   1.111   1.392   1.318   1.131
178   Q         0.518   0.500   0.305   0.745   0.722   0.428   0.521   0.496   0.187
179   Y        -0.606  -0.586  -0.556  -0.414  -0.382  -0.328  -0.697  -0.676  -0.615
180   I         1.299   1.316   1.163   1.499   1.526   1.334   1.392   1.417   1.123
181   D         0.518   0.545   0.320   0.634   0.673   0.338   0.521   0.562   0.211
182   H         2.129   2.153   2.244   2.324   2.362   2.500   2.436   2.472   2.629
183   L         0.518   0.496   0.331   0.564   0.538   0.312   0.521   0.490   0.227
184   N         2.129   2.153   2.244   2.107   2.142   2.280   2.436   2.472   2.629
185   H         0.748   0.781   0.851   0.585   0.634   0.736   0.347   0.408   0.494
186   K         0.196   0.171   0.148   0.094   0.068   0.075  -0.001  -0.036  -0.070
187   V        -0.455  -0.401  -0.470  -0.395  -0.314  -0.417  -0.523  -0.457  -0.517
188   H         2.129   2.153   2.244   2.324   2.362   2.500   2.436   2.472   2.629
189   A        -0.855  -0.863  -0.906  -0.573  -0.592  -0.673  -0.697  -0.702  -0.728
190   I        -1.808  -1.814  -1.731  -1.434  -1.440  -1.316  -1.219  -1.220  -1.114
191   K         0.768   0.777   0.843   0.331   0.341   0.439   0.389   0.400   0.478
192   F         0.207   0.169   0.114   0.257   0.197   0.065   0.048  -0.008  -0.110
193   E         0.207   0.169   0.114   0.222   0.165   0.072   0.048  -0.008  -0.110
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   N         0.207   0.177   0.161   0.143   0.090   0.052   0.048   0.003  -0.037
197   L         1.117   1.149   1.044   0.994   1.038   0.883   1.071   1.126   0.891
198   F         0.207   0.169   0.114   0.389   0.341   0.251   0.048  -0.008  -0.110
199   D        -1.127  -1.129  -1.044  -1.102  -1.101  -0.979  -0.976  -0.974  -0.865
200   E         0.207   0.169   0.114   0.089   0.025  -0.116   0.048  -0.008  -0.110
201   P         0.207   0.169   0.114   0.489   0.432   0.322   0.048  -0.008  -0.110
202   L         0.207   0.169   0.114   0.033  -0.031  -0.137   0.048  -0.008  -0.110
203   I         0.207   0.169   0.114   0.287   0.226   0.112   0.048  -0.008  -0.110
204   I        -1.127  -1.129  -1.044  -1.140  -1.137  -1.017  -0.976  -0.974  -0.865
205   D         0.097   0.090   0.124  -0.113  -0.126  -0.063  -0.175  -0.179  -0.122
206   I         0.196   0.190   0.176   0.241   0.235   0.220  -0.001  -0.005  -0.032
207   R        -0.054  -0.072   0.011  -0.262  -0.302  -0.175  -0.349  -0.375  -0.265
208   D        -0.855  -0.925  -0.950  -0.654  -0.757  -0.800  -0.697  -0.767  -0.773
209   N        -0.054  -0.072   0.011  -0.285  -0.321  -0.205  -0.349  -0.375  -0.265
210   D         0.518   0.485   0.320   0.653   0.612   0.367   0.521   0.474   0.211
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -         0.026   0.031   0.073  -0.127  -0.120  -0.078  -0.229  -0.221  -0.172
213   -         0.026   0.029   0.082   0.197   0.207   0.281  -0.229  -0.224  -0.159
214   -         2.129   2.153   2.244   2.049   2.082   2.221   2.436   2.472   2.629
215   D        -1.007  -1.023  -0.996  -1.062  -1.084  -1.063  -0.871  -0.881  -0.823
216   V        -0.455  -0.459  -0.459  -0.302  -0.301  -0.300  -0.523  -0.514  -0.502
217   P         0.097   0.093   0.101   0.145   0.134   0.151  -0.175  -0.174  -0.149
218   Q        -0.855  -0.833  -0.885  -0.666  -0.634  -0.688  -0.697  -0.668  -0.706
219   E        -0.205  -0.191  -0.367  -0.112  -0.094  -0.345  -0.175  -0.153  -0.376
220   E         1.299   1.258   1.168   1.272   1.215   1.098   1.392   1.318   1.131
221   F         0.919   0.970   0.961   0.985   1.069   1.038   0.695   0.788   0.725
222   E        -1.407  -1.424  -1.363  -1.121  -1.132  -1.044  -1.045  -1.056  -0.967
223   L        -0.455  -0.499  -0.470  -0.632  -0.698  -0.663  -0.523  -0.567  -0.519
224   C        -1.007  -0.961  -0.992  -0.855  -0.815  -0.808  -0.871  -0.828  -0.819
225   Y        -1.007  -1.009  -0.983  -0.734  -0.740  -0.680  -0.871  -0.868  -0.810
226   H        -0.054  -0.033   0.029  -0.331  -0.324  -0.230  -0.349  -0.318  -0.240
227   N        -1.808  -1.814  -1.731  -1.599  -1.578  -1.484  -1.219  -1.220  -1.114
228   L         0.518   0.568   0.325   0.474   0.547   0.162   0.521   0.598   0.218
229   I        -0.205  -0.232  -0.361   0.174   0.142  -0.024  -0.175  -0.207  -0.368
230   K        -1.407  -1.377  -1.381  -1.426  -1.365  -1.397  -1.045  -1.014  -0.983
231   D        -0.855  -0.819  -0.896  -0.934  -0.885  -0.992  -0.697  -0.653  -0.717
232   F        -0.455  -0.507  -0.491  -0.499  -0.592  -0.610  -0.523  -0.580  -0.543
233   V        -1.007  -1.045  -0.980  -0.752  -0.808  -0.710  -0.871  -0.900  -0.808
234   E        -1.407  -1.430  -1.357  -1.313  -1.350  -1.237  -1.045  -1.060  -0.962
235   V        -1.407  -1.424  -1.363  -1.169  -1.201  -1.099  -1.045  -1.056  -0.967
236   R        -0.855  -0.819  -0.896  -0.965  -0.920  -1.031  -0.697  -0.653  -0.717
237   S        -1.007  -1.018  -0.961  -1.133  -1.158  -1.077  -0.871  -0.877  -0.792
238   M        -1.407  -1.377  -1.381  -1.235  -1.202  -1.181  -1.045  -1.014  -0.983
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -0.676  -0.678  -0.588  -0.755  -0.758  -0.627  -0.762  -0.761  -0.646
245   -        -0.676  -0.678  -0.588  -0.820  -0.826  -0.693  -0.762  -0.761  -0.646
246   -        -0.676  -0.678  -0.588  -0.591  -0.588  -0.460  -0.762  -0.761  -0.646
247   -        -0.676  -0.678  -0.588  -0.801  -0.802  -0.674  -0.762  -0.761  -0.646
248   -         0.026   0.040   0.075   0.066   0.090   0.130  -0.229  -0.207  -0.170
249   -         0.026   0.031   0.073  -0.178  -0.171  -0.130  -0.229  -0.221  -0.172
250   -         0.026   0.029   0.082  -0.157  -0.155  -0.077  -0.229  -0.224  -0.159
251   -         2.129   2.153   2.244   2.049   2.082   2.221   2.436   2.472   2.629
252   -         0.026   0.040   0.075   0.049   0.073   0.112  -0.229  -0.207  -0.170
253   -        -0.566  -0.583  -0.514  -0.633  -0.649  -0.554  -0.634  -0.652  -0.560
254   -        -0.566  -0.537  -0.520  -0.593  -0.532  -0.541  -0.634  -0.594  -0.567
255   -         1.117   1.060   1.045   1.122   1.042   1.014   1.071   0.960   0.894
256   -        -0.566  -0.578  -0.543  -0.665  -0.664  -0.603  -0.634  -0.646  -0.595
257   -        -0.566  -0.586  -0.543  -0.607  -0.639  -0.561  -0.634  -0.656  -0.594
258   -        -1.029  -1.022  -0.977  -0.949  -0.939  -0.867  -0.881  -0.869  -0.801
259   -        -0.561  -0.550  -0.519  -0.687  -0.672  -0.614  -0.644  -0.629  -0.573
260   -        -0.561  -0.551  -0.518  -0.797  -0.787  -0.741  -0.644  -0.630  -0.571
261   E        -1.007  -0.983  -0.966  -1.176  -1.139  -1.113  -0.871  -0.847  -0.797
262   T        -1.407  -1.384  -1.363  -1.328  -1.292  -1.285  -1.045  -1.020  -0.967
263   Q        -0.054  -0.039   0.028  -0.339  -0.325  -0.227  -0.349  -0.326  -0.241
264   S        -1.007  -1.042  -0.965  -1.068  -1.133  -1.021  -0.871  -0.897  -0.795
265   K         0.518   0.545   0.320   0.394   0.426   0.112   0.521   0.562   0.211
266   R         0.748   0.765   0.838   0.264   0.283   0.392   0.347   0.375   0.468
267   K         0.196   0.192   0.155  -0.083  -0.088  -0.136  -0.001  -0.000  -0.064
268   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   D         0.083   0.101   0.106  -0.151  -0.125  -0.118  -0.170  -0.140  -0.136
276   V        -0.385  -0.354  -0.442  -0.337  -0.294  -0.439  -0.407  -0.364  -0.471
277   E        -0.385  -0.273  -0.442  -0.555  -0.390  -0.644  -0.407  -0.259  -0.471
278   K        -0.561  -0.581  -0.539  -0.790  -0.801  -0.735  -0.644  -0.659  -0.594
279   A        -0.676  -0.662  -0.588  -0.538  -0.529  -0.407  -0.762  -0.745  -0.646
280   K        -1.029  -0.971  -0.985  -1.081  -0.954  -1.046  -0.881  -0.817  -0.808
281   K        -0.205  -0.229  -0.335  -0.325  -0.362  -0.527  -0.175  -0.202  -0.335
282   V        -1.496  -1.503  -1.416  -1.470  -1.488  -1.353  -1.118  -1.119  -1.010
283   A        -1.029  -1.008  -1.005  -1.157  -1.132  -1.136  -0.881  -0.855  -0.828
284   T        -1.029  -1.008  -1.005  -1.161  -1.138  -1.141  -0.881  -0.855  -0.828
285   K         0.374   0.388   0.250   0.174   0.194  -0.021   0.304   0.326   0.101
286   P        -1.029  -1.024  -1.004  -0.723  -0.718  -0.678  -0.881  -0.871  -0.827
287   S        -0.385  -0.377  -0.409  -0.612  -0.602  -0.661  -0.407  -0.394  -0.429
288   I        -1.496  -1.503  -1.416  -1.381  -1.404  -1.263  -1.118  -1.119  -1.010
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   E        -0.855  -0.881  -0.909  -0.649  -0.685  -0.702  -0.697  -0.721  -0.731
303   S        -1.407  -1.400  -1.357  -1.092  -1.079  -1.008  -1.045  -1.035  -0.962
304   E        -0.606  -0.588  -0.542  -0.717  -0.696  -0.616  -0.697  -0.678  -0.601
305   S        -0.455  -0.442  -0.471  -0.456  -0.413  -0.465  -0.523  -0.494  -0.516
306   K        -1.007  -0.989  -0.964  -1.099  -1.064  -1.041  -0.871  -0.852  -0.795
307   V         0.196   0.228   0.170   0.383   0.417   0.366  -0.001   0.027  -0.035
308   S        -1.407  -1.377  -1.381  -1.100  -1.036  -1.093  -1.045  -1.014  -0.983
309   Q        -1.407  -1.377  -1.381  -1.275  -1.224  -1.260  -1.045  -1.014  -0.983
310   M        -0.606  -0.604  -0.543  -0.521  -0.520  -0.418  -0.697  -0.692  -0.602
311   M         2.129   2.153   2.244   2.349   2.384   2.525   2.436   2.472   2.629
312   G         2.129   2.153   2.244   2.200   2.230   2.374   2.436   2.472   2.629
313   F         2.129   2.153   2.244   2.229   2.269   2.404   2.436   2.472   2.629
314   S        -0.606  -0.613  -0.543  -0.648  -0.650  -0.543  -0.697  -0.699  -0.602
315   N        -1.007  -1.002  -0.997  -0.933  -0.918  -0.928  -0.871  -0.862  -0.823
316   F         2.129   2.153   2.244   2.229   2.269   2.404   2.436   2.472   2.629
317   A         1.218   1.268   1.118   1.345   1.412   1.206   1.252   1.336   1.037
318   T         0.374   0.385   0.257   0.436   0.458   0.272   0.304   0.321   0.112
319   S         0.083   0.087   0.099   0.020   0.042   0.067  -0.170  -0.155  -0.142
320   K         2.129   2.153   2.244   1.838   1.870   2.007   2.436   2.472   2.629
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   K         0.518   0.509   0.328   0.366   0.353   0.079   0.521   0.509   0.223
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12368
Output conservation file - output/Q12368
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
