1     M         1.870   1.878   1.923   2.204   2.218   2.290   2.076   2.089   2.158
2     A        -1.012  -1.009  -0.958  -0.891  -0.873  -0.804  -0.920  -0.915  -0.844
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     F         0.547   0.505   0.541   0.556   0.469   0.527   0.300   0.220   0.269
10    K        -1.476  -1.473  -1.422  -1.310  -1.302  -1.223  -1.120  -1.114  -1.044
11    L         0.830   0.815   0.701   0.587   0.578   0.391   0.798   0.773   0.563
12    W        -0.323  -0.300  -0.309  -0.354  -0.330  -0.307  -0.481  -0.452  -0.449
13    L        -0.899  -0.924  -0.911  -0.995  -1.010  -0.973  -0.800  -0.825  -0.795
14    L         0.471   0.495   0.518   0.044   0.101   0.114   0.158   0.201   0.225
15    D        -0.105  -0.147  -0.217   0.000  -0.067  -0.181  -0.161  -0.219  -0.315
16    E        -0.105  -0.147  -0.217   0.020  -0.040  -0.131  -0.161  -0.219  -0.315
17    E        -0.323  -0.337  -0.307  -0.417  -0.436  -0.380  -0.481  -0.494  -0.446
18    T        -0.323  -0.316  -0.311  -0.415  -0.404  -0.385  -0.481  -0.470  -0.451
19    I        -0.105  -0.081  -0.186  -0.228  -0.185  -0.380  -0.161  -0.126  -0.271
20    Y        -0.899  -0.924  -0.911  -0.916  -0.964  -0.978  -0.800  -0.825  -0.795
21    E         0.471   0.460   0.497   0.283   0.261   0.318   0.158   0.136   0.184
22    H         0.471   0.484   0.512   0.577   0.598   0.640   0.158   0.180   0.214
23    V         0.471   0.471   0.501   0.245   0.239   0.280   0.158   0.157   0.192
24    F         0.830   0.815   0.701   1.060   1.040   0.876   0.798   0.773   0.563
25    E         1.870   1.878   1.923   1.875   1.889   1.961   2.076   2.089   2.158
26    R         0.471   0.460   0.497   0.258   0.231   0.261   0.158   0.136   0.184
27    Y         0.830   0.815   0.701   1.095   1.076   0.904   0.798   0.773   0.563
28    T        -0.323  -0.307  -0.310  -0.543  -0.527  -0.514  -0.481  -0.460  -0.449
29    Q        -0.899  -0.887  -0.890  -0.853  -0.843  -0.835  -0.800  -0.785  -0.773
30    L        -0.899  -0.924  -0.911  -0.998  -1.010  -0.976  -0.800  -0.825  -0.795
31    E        -0.899  -0.924  -0.911  -0.856  -0.897  -0.868  -0.800  -0.825  -0.795
32    G        -1.012  -1.003  -0.958  -0.928  -0.917  -0.841  -0.920  -0.908  -0.844
33    Q        -1.012  -1.003  -0.958  -0.866  -0.847  -0.779  -0.920  -0.908  -0.844
34    S         0.429   0.436   0.483   0.214   0.203   0.297   0.079   0.089   0.158
35    G        -0.414  -0.410  -0.360  -0.460  -0.459  -0.374  -0.587  -0.581  -0.510
36    K        -1.012  -1.003  -0.958  -1.016  -1.004  -0.928  -0.920  -0.908  -0.844
37    L        -0.105  -0.116  -0.201  -0.356  -0.361  -0.500  -0.161  -0.174  -0.292
38    A        -0.899  -0.903  -0.893  -0.710  -0.717  -0.703  -0.800  -0.802  -0.776
39    Q         0.830   0.797   0.707   1.009   0.959   0.821   0.798   0.743   0.573
40    D        -0.105  -0.147  -0.217  -0.040  -0.111  -0.234  -0.161  -0.219  -0.315
41    L         1.870   1.878   1.923   1.605   1.630   1.691   2.076   2.089   2.158
42    G         1.870   1.878   1.923   2.017   2.031   2.102   2.076   2.089   2.158
43    I        -0.105  -0.147  -0.217  -0.036  -0.098  -0.187  -0.161  -0.219  -0.315
44    Q        -0.323  -0.307  -0.310  -0.468  -0.442  -0.463  -0.481  -0.460  -0.449
45    D        -0.105  -0.100  -0.191  -0.040  -0.032  -0.187  -0.161  -0.153  -0.278
46    R         0.471   0.471   0.497   0.363   0.359   0.381   0.158   0.156   0.185
47    R        -1.476  -1.473  -1.422  -1.229  -1.230  -1.141  -1.120  -1.114  -1.044
48    G        -0.899  -0.886  -0.889  -0.883  -0.866  -0.855  -0.800  -0.784  -0.772
49    G        -1.476  -1.473  -1.422  -1.387  -1.386  -1.299  -1.120  -1.114  -1.044
50    V        -0.899  -0.887  -0.890  -0.824  -0.803  -0.803  -0.800  -0.785  -0.773
51    L        -0.105  -0.147  -0.217  -0.373  -0.429  -0.548  -0.161  -0.219  -0.315
52    E        -0.323  -0.316  -0.311  -0.468  -0.459  -0.438  -0.481  -0.470  -0.451
53    I        -0.105  -0.147  -0.217  -0.091  -0.158  -0.258  -0.161  -0.219  -0.315
54    T        -0.899  -0.895  -0.887  -0.954  -0.952  -0.939  -0.800  -0.793  -0.769
55    F        -0.899  -0.907  -0.905  -0.921  -0.940  -0.924  -0.800  -0.807  -0.789
56    E        -1.476  -1.473  -1.422  -1.195  -1.186  -1.107  -1.120  -1.114  -1.044
57    P        -0.105  -0.147  -0.217   0.184   0.117   0.006  -0.161  -0.219  -0.315
58    S        -0.899  -0.903  -0.893  -0.777  -0.791  -0.745  -0.800  -0.802  -0.776
59    G        -0.323  -0.308  -0.299  -0.251  -0.230  -0.203  -0.481  -0.462  -0.437
60    L        -0.899  -0.924  -0.911  -1.246  -1.277  -1.256  -0.800  -0.825  -0.795
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    E        -0.414  -0.410  -0.360  -0.616  -0.613  -0.529  -0.587  -0.581  -0.510
66    G        -0.414  -0.410  -0.360  -0.481  -0.479  -0.394  -0.587  -0.581  -0.510
67    G        -0.414  -0.410  -0.360  -0.501  -0.499  -0.414  -0.587  -0.581  -0.510
68    R        -0.414  -0.410  -0.360  -0.498  -0.495  -0.411  -0.587  -0.581  -0.510
69    K         1.870   1.878   1.923   1.974   1.987   2.060   2.076   2.089   2.158
70    K         1.870   1.878   1.923   1.974   1.987   2.060   2.076   2.089   2.158
71    K        -0.414  -0.410  -0.360  -0.348  -0.340  -0.261  -0.587  -0.581  -0.510
72    R        -0.414  -0.410  -0.360  -0.361  -0.356  -0.274  -0.587  -0.581  -0.510
73    V        -0.414  -0.410  -0.360  -0.549  -0.546  -0.462  -0.587  -0.581  -0.510
74    R         0.547   0.547   0.536   0.555   0.553   0.523   0.300   0.298   0.260
75    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    D         1.870   1.878   1.923   1.902   1.913   1.987   2.076   2.089   2.158
92    S        -0.414  -0.410  -0.360  -0.563  -0.558  -0.476  -0.587  -0.581  -0.510
93    Y         1.870   1.878   1.923   2.062   2.075   2.148   2.076   2.089   2.158
94    H        -1.476  -1.473  -1.422  -1.368  -1.372  -1.280  -1.120  -1.114  -1.044
95    V        -0.899  -0.907  -0.905  -0.930  -0.955  -0.972  -0.800  -0.807  -0.789
96    S        -0.899  -0.924  -0.911  -0.949  -0.990  -0.958  -0.800  -0.825  -0.795
97    V        -0.105  -0.089  -0.191  -0.228  -0.204  -0.391  -0.161  -0.137  -0.279
98    G        -0.899  -0.896  -0.886  -0.633  -0.634  -0.619  -0.800  -0.795  -0.769
99    Q         1.870   1.878   1.923   2.009   2.020   2.095   2.076   2.089   2.158
100   S         0.471   0.484   0.512   0.223   0.238   0.289   0.158   0.180   0.214
101   I        -0.899  -0.887  -0.890  -1.192  -1.164  -1.168  -0.800  -0.785  -0.773
102   S        -0.105  -0.089  -0.191  -0.081  -0.055  -0.219  -0.161  -0.137  -0.279
103   S        -0.105  -0.147  -0.217  -0.154  -0.224  -0.330  -0.161  -0.219  -0.315
104   L         1.870   1.878   1.923   1.605   1.630   1.691   2.076   2.089   2.158
105   R        -0.899  -0.896  -0.886  -0.630  -0.630  -0.597  -0.800  -0.795  -0.769
106   S         0.830   0.797   0.707   0.799   0.748   0.617   0.798   0.743   0.573
107   S        -1.012  -1.001  -0.958  -1.054  -1.036  -0.967  -0.920  -0.906  -0.844
108   R         0.701   0.623   0.619   0.855   0.734   0.712   0.578   0.438   0.413
109   D         1.870   1.878   1.923   1.902   1.913   1.987   2.076   2.089   2.158
110   N         0.471   0.460   0.497   0.270   0.235   0.291   0.158   0.136   0.184
111   G        -0.899  -0.887  -0.890  -0.724  -0.710  -0.705  -0.800  -0.785  -0.773
112   N         0.471   0.460   0.497   0.408   0.382   0.446   0.158   0.136   0.184
113   S         1.870   1.878   1.923   1.796   1.805   1.881   2.076   2.089   2.158
114   T         0.830   0.797   0.707   0.834   0.782   0.631   0.798   0.743   0.573
115   T         1.870   1.878   1.923   1.872   1.884   1.957   2.076   2.089   2.158
116   G         1.870   1.878   1.923   2.017   2.031   2.102   2.076   2.089   2.158
117   Y        -0.105  -0.147  -0.217   0.184   0.119   0.011  -0.161  -0.219  -0.315
118   V         0.830   0.797   0.707   0.879   0.827   0.678   0.798   0.743   0.573
119   L        -0.105  -0.114  -0.192  -0.275  -0.269  -0.385  -0.161  -0.173  -0.280
120   W         1.870   1.878   1.923   2.197   2.211   2.282   2.076   2.089   2.158
121   S        -0.899  -0.914  -0.906  -0.909  -0.933  -0.907  -0.800  -0.815  -0.790
122   T        -0.899  -0.924  -0.911  -1.085  -1.130  -1.130  -0.800  -0.825  -0.795
123   T         0.471   0.488   0.514   0.172   0.198   0.239   0.158   0.189   0.216
124   P        -0.105  -0.114  -0.192   0.085   0.067  -0.076  -0.161  -0.173  -0.280
125   F        -0.105  -0.116  -0.201   0.038   0.018  -0.134  -0.161  -0.174  -0.292
126   F         0.830   0.858   0.718   0.999   1.041   0.816   0.798   0.844   0.593
127   I        -0.899  -0.895  -0.887  -0.894  -0.878  -0.868  -0.800  -0.793  -0.769
128   N        -1.476  -1.473  -1.422  -1.401  -1.404  -1.313  -1.120  -1.114  -1.044
129   W         1.870   1.878   1.923   2.197   2.211   2.282   2.076   2.089   2.158
130   L         0.830   0.815   0.701   0.597   0.588   0.405   0.798   0.773   0.563
131   L         0.830   0.797   0.707   0.575   0.538   0.382   0.798   0.743   0.573
132   Y         0.701   0.630   0.619   0.862   0.742   0.710   0.578   0.451   0.413
133   S        -0.291  -0.309  -0.301  -0.217  -0.235  -0.236  -0.421  -0.446  -0.431
134   T        -1.012  -1.003  -0.958  -1.175  -1.177  -1.088  -0.920  -0.908  -0.844
135   S        -1.012  -1.003  -0.958  -1.037  -1.035  -0.950  -0.920  -0.908  -0.844
136   A         1.870   1.878   1.923   2.095   2.109   2.181   2.076   2.089   2.158
137   A        -0.414  -0.410  -0.360  -0.536  -0.536  -0.448  -0.587  -0.581  -0.510
138   P         0.547   0.544   0.541   0.560   0.550   0.520   0.300   0.293   0.269
139   F         0.547   0.547   0.536   0.420   0.419   0.351   0.300   0.298   0.260
140   R        -0.414  -0.410  -0.360  -0.387  -0.383  -0.300  -0.587  -0.581  -0.510
141   L         0.547   0.567   0.542   0.383   0.428   0.330   0.300   0.335   0.270
142   G         0.547   0.547   0.536   0.630   0.630   0.607   0.300   0.298   0.260
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   S        -0.414  -0.410  -0.360  -0.546  -0.540  -0.459  -0.587  -0.581  -0.510
147   Q        -0.414  -0.410  -0.360  -0.322  -0.319  -0.235  -0.587  -0.581  -0.510
148   V         1.870   1.878   1.923   1.919   1.932   2.004   2.076   2.089   2.158
149   E        -0.414  -0.410  -0.360  -0.556  -0.554  -0.469  -0.587  -0.581  -0.510
150   V         0.429   0.436   0.483   0.165   0.178   0.255   0.079   0.089   0.158
151   T        -0.291  -0.323  -0.307  -0.206  -0.252  -0.206  -0.421  -0.465  -0.439
152   C        -0.291  -0.309  -0.301  -0.307  -0.350  -0.302  -0.421  -0.446  -0.431
153   G        -1.012  -1.003  -0.958  -1.163  -1.131  -1.075  -0.920  -0.908  -0.844
154   S        -0.291  -0.258  -0.288  -0.420  -0.377  -0.409  -0.421  -0.373  -0.413
155   S        -1.012  -1.003  -0.958  -0.944  -0.932  -0.857  -0.920  -0.908  -0.844
156   C         0.429   0.438   0.485   0.467   0.470   0.550   0.079   0.093   0.161
157   E        -1.012  -1.003  -0.958  -0.999  -0.981  -0.912  -0.920  -0.908  -0.844
158   G         0.547   0.570   0.555   0.474   0.517   0.470   0.300   0.340   0.294
159   H         0.547   0.512   0.541   0.660   0.588   0.630   0.300   0.234   0.269
160   K         0.547   0.570   0.555   0.490   0.530   0.491   0.300   0.340   0.294
161   L        -0.414  -0.406  -0.360  -0.904  -0.884  -0.817  -0.587  -0.576  -0.510
162   E         0.547   0.512   0.541   0.356   0.276   0.318   0.300   0.234   0.269
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   L        -1.012  -1.009  -0.958  -1.257  -1.253  -1.169  -0.920  -0.915  -0.844
167   P         1.870   1.878   1.923   2.084   2.096   2.170   2.076   2.089   2.158
168   R        -0.291  -0.292  -0.284  -0.417  -0.425  -0.395  -0.421  -0.421  -0.407
169   L        -0.291  -0.280  -0.302  -0.485  -0.458  -0.477  -0.421  -0.404  -0.432
170   V        -1.012  -1.009  -0.958  -1.052  -1.048  -0.964  -0.920  -0.915  -0.844
171   D         0.547   0.582   0.558   0.537   0.599   0.544   0.300   0.363   0.301
172   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   G         0.547   0.541   0.550   0.582   0.569   0.574   0.300   0.288   0.285
180   A        -0.291  -0.285  -0.285  -0.193  -0.185  -0.184  -0.421  -0.410  -0.409
181   D        -0.291  -0.294  -0.307  -0.370  -0.368  -0.416  -0.421  -0.423  -0.439
182   R        -1.012  -1.010  -0.958  -0.964  -0.964  -0.877  -0.920  -0.915  -0.844
183   G        -0.899  -0.887  -0.890  -0.760  -0.744  -0.747  -0.800  -0.785  -0.773
184   K        -0.899  -0.865  -0.898  -0.985  -0.921  -0.991  -0.800  -0.759  -0.781
185   R        -0.899  -0.924  -0.911  -0.757  -0.800  -0.792  -0.800  -0.825  -0.795
186   G        -0.899  -0.877  -0.884  -0.836  -0.810  -0.807  -0.800  -0.773  -0.767
187   I         0.471   0.475   0.500   0.245   0.247   0.279   0.158   0.164   0.191
188   L         0.830   0.839   0.710   0.575   0.600   0.388   0.798   0.812   0.579
189   E         1.870   1.878   1.923   1.875   1.889   1.961   2.076   2.089   2.158
190   L         1.870   1.878   1.923   1.605   1.630   1.691   2.076   2.089   2.158
191   G         1.870   1.878   1.923   2.017   2.031   2.102   2.076   2.089   2.158
192   A        -0.899  -0.877  -0.884  -0.811  -0.781  -0.773  -0.800  -0.773  -0.767
193   G         1.870   1.878   1.923   2.017   2.031   2.102   2.076   2.089   2.158
194   I        -0.899  -0.914  -0.906  -0.953  -0.983  -0.961  -0.800  -0.815  -0.790
195   S        -0.105  -0.147  -0.217  -0.129  -0.198  -0.298  -0.161  -0.219  -0.315
196   G        -0.105  -0.081  -0.186   0.073   0.108  -0.059  -0.161  -0.126  -0.271
197   I        -0.899  -0.895  -0.887  -0.941  -0.941  -0.919  -0.800  -0.793  -0.769
198   L        -0.105  -0.114  -0.192  -0.206  -0.202  -0.298  -0.161  -0.173  -0.280
199   P         0.471   0.460   0.497   0.521   0.496   0.553   0.158   0.136   0.184
200   V        -0.899  -0.907  -0.905  -0.872  -0.886  -0.869  -0.800  -0.807  -0.789
201   I        -0.105  -0.070  -0.184  -0.173  -0.112  -0.333  -0.161  -0.110  -0.268
202   L        -0.323  -0.318  -0.298  -0.456  -0.443  -0.396  -0.481  -0.473  -0.436
203   G        -0.899  -0.907  -0.905  -0.995  -1.018  -1.002  -0.800  -0.807  -0.789
204   N        -0.105  -0.147  -0.217   0.018  -0.055  -0.164  -0.161  -0.219  -0.315
205   F        -0.899  -0.914  -0.906  -0.792  -0.821  -0.816  -0.800  -0.815  -0.790
206   V         1.870   1.878   1.923   1.909   1.921   1.995   2.076   2.089   2.158
207   D        -0.899  -0.924  -0.911  -0.730  -0.768  -0.739  -0.800  -0.825  -0.795
208   T        -0.105  -0.114  -0.192   0.009  -0.002  -0.107  -0.161  -0.173  -0.280
209   Y         0.830   0.797   0.707   1.095   1.050   0.912   0.798   0.743   0.573
210   V         0.471   0.466   0.496   0.245   0.228   0.270   0.158   0.147   0.183
211   S        -0.105  -0.070  -0.184   0.123   0.177   0.000  -0.161  -0.110  -0.268
212   T         1.870   1.878   1.923   1.872   1.884   1.957   2.076   2.089   2.158
213   D         1.870   1.878   1.923   1.943   1.956   2.028   2.076   2.089   2.158
214   Q         1.870   1.878   1.923   2.009   2.020   2.095   2.076   2.089   2.158
215   K        -0.105  -0.116  -0.201   0.110   0.095  -0.028  -0.161  -0.174  -0.292
216   G        -0.323  -0.307  -0.310  -0.192  -0.165  -0.166  -0.481  -0.460  -0.449
217   I        -0.105  -0.147  -0.217  -0.228  -0.299  -0.440  -0.161  -0.219  -0.315
218   L         1.870   1.878   1.923   1.605   1.630   1.691   2.076   2.089   2.158
219   N        -0.323  -0.307  -0.310  -0.281  -0.262  -0.243  -0.481  -0.460  -0.449
220   K        -0.899  -0.865  -0.898  -0.980  -0.927  -0.946  -0.800  -0.759  -0.781
221   L         0.830   0.815   0.701   0.587   0.578   0.391   0.798   0.773   0.563
222   K         0.830   0.797   0.707   1.014   0.970   0.837   0.798   0.743   0.573
223   D        -0.323  -0.328  -0.304  -0.313  -0.320  -0.272  -0.481  -0.484  -0.443
224   N         1.870   1.878   1.923   1.958   1.967   2.043   2.076   2.089   2.158
225   I         1.870   1.878   1.923   1.826   1.837   1.912   2.076   2.089   2.158
226   M        -0.899  -0.865  -0.898  -0.686  -0.645  -0.662  -0.800  -0.759  -0.781
227   E        -0.323  -0.328  -0.304  -0.437  -0.446  -0.400  -0.481  -0.484  -0.443
228   N         1.870   1.878   1.923   1.958   1.967   2.043   2.076   2.089   2.158
229   L        -0.105  -0.114  -0.192  -0.310  -0.314  -0.428  -0.161  -0.173  -0.280
230   S         0.830   0.839   0.710   0.795   0.805   0.617   0.798   0.812   0.579
231   Q        -1.476  -1.473  -1.422  -1.383  -1.373  -1.296  -1.120  -1.114  -1.044
232   L        -1.476  -1.473  -1.422  -1.264  -1.242  -1.176  -1.120  -1.114  -1.044
233   T        -0.899  -0.895  -0.887  -0.780  -0.775  -0.750  -0.800  -0.793  -0.769
234   R        -0.323  -0.316  -0.311  -0.375  -0.374  -0.350  -0.481  -0.470  -0.451
235   K        -0.323  -0.300  -0.309  -0.230  -0.198  -0.201  -0.481  -0.452  -0.449
236   R        -0.899  -0.886  -0.889  -1.015  -0.992  -1.008  -0.800  -0.784  -0.772
237   C        -0.899  -0.886  -0.889  -0.998  -0.981  -0.984  -0.800  -0.784  -0.772
238   I        -1.476  -1.473  -1.422  -1.252  -1.243  -1.165  -1.120  -1.114  -1.044
239   S         0.830   0.797   0.707   0.807   0.757   0.628   0.798   0.743   0.573
240   R        -1.476  -1.473  -1.422  -1.288  -1.290  -1.200  -1.120  -1.114  -1.044
241   S         0.471   0.484   0.512   0.172   0.190   0.236   0.158   0.180   0.214
242   L         0.547   0.544   0.541   0.086   0.087   0.067   0.300   0.293   0.269
243   R        -0.414  -0.410  -0.360  -0.404  -0.400  -0.317  -0.587  -0.581  -0.510
244   L         0.547   0.547   0.536   0.086   0.092   0.058   0.300   0.298   0.260
245   E        -0.414  -0.410  -0.360  -0.655  -0.653  -0.568  -0.587  -0.581  -0.510
246   L        -0.414  -0.410  -0.360  -0.732  -0.718  -0.645  -0.587  -0.581  -0.510
247   P        -0.414  -0.410  -0.360  -0.717  -0.716  -0.630  -0.587  -0.581  -0.510
248   T        -0.414  -0.410  -0.360  -0.474  -0.468  -0.387  -0.587  -0.581  -0.510
249   V        -0.414  -0.410  -0.360  -0.529  -0.524  -0.442  -0.587  -0.581  -0.510
250   E        -0.414  -0.410  -0.360  -0.450  -0.444  -0.363  -0.587  -0.581  -0.510
251   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   P         0.547   0.505   0.541   0.634   0.556   0.609   0.300   0.220   0.269
264   S        -1.476  -1.473  -1.422  -1.449  -1.440  -1.361  -1.120  -1.114  -1.044
265   K        -0.105  -0.114  -0.192   0.027   0.012  -0.119  -0.161  -0.173  -0.280
266   S        -0.899  -0.877  -0.884  -0.834  -0.784  -0.829  -0.800  -0.773  -0.767
267   T        -0.899  -0.914  -0.906  -0.793  -0.810  -0.790  -0.800  -0.815  -0.790
268   L        -1.476  -1.473  -1.422  -1.305  -1.284  -1.217  -1.120  -1.114  -1.044
269   H        -0.899  -0.907  -0.905  -0.756  -0.779  -0.771  -0.800  -0.807  -0.789
270   L         0.471   0.471   0.501  -0.023  -0.015   0.025   0.158   0.157   0.192
271   E         0.471   0.471   0.501   0.283   0.281   0.326   0.158   0.157   0.192
272   V        -0.105  -0.100  -0.191   0.012   0.023  -0.113  -0.161  -0.153  -0.278
273   A        -0.105  -0.147  -0.217   0.162   0.095  -0.004  -0.161  -0.219  -0.315
274   A        -0.899  -0.865  -0.898  -1.010  -0.948  -1.019  -0.800  -0.759  -0.781
275   L         0.830   0.797   0.707   0.629   0.597   0.461   0.798   0.743   0.573
276   D         1.870   1.878   1.923   1.943   1.956   2.028   2.076   2.089   2.158
277   W         1.870   1.878   1.923   2.197   2.211   2.282   2.076   2.089   2.158
278   E         1.870   1.878   1.923   1.875   1.889   1.961   2.076   2.089   2.158
279   K        -1.476  -1.473  -1.422  -1.502  -1.488  -1.414  -1.120  -1.114  -1.044
280   I        -0.323  -0.330  -0.304  -0.360  -0.373  -0.322  -0.481  -0.486  -0.443
281   N        -0.899  -0.865  -0.898  -0.851  -0.800  -0.844  -0.800  -0.759  -0.781
282   L        -1.476  -1.473  -1.422  -1.325  -1.298  -1.238  -1.120  -1.114  -1.044
283   Q        -0.105  -0.103  -0.188  -0.092  -0.093  -0.206  -0.161  -0.157  -0.274
284   D        -0.899  -0.887  -0.890  -0.711  -0.689  -0.694  -0.800  -0.785  -0.773
285   K        -0.105  -0.147  -0.217   0.075   0.009  -0.099  -0.161  -0.219  -0.315
286   K        -0.323  -0.338  -0.307  -0.441  -0.466  -0.403  -0.481  -0.496  -0.446
287   T        -0.899  -0.865  -0.898  -0.848  -0.798  -0.833  -0.800  -0.759  -0.781
288   H        -1.476  -1.473  -1.422  -1.234  -1.238  -1.147  -1.120  -1.114  -1.044
289   S         0.471   0.477   0.499   0.214   0.219   0.258   0.158   0.167   0.189
290   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   P        -0.323  -0.337  -0.307  -0.373  -0.405  -0.366  -0.481  -0.494  -0.446
293   E        -0.899  -0.896  -0.886  -0.903  -0.900  -0.886  -0.800  -0.795  -0.769
294   L        -0.105  -0.147  -0.217  -0.200  -0.242  -0.321  -0.161  -0.219  -0.315
295   S        -0.899  -0.887  -0.890  -0.867  -0.848  -0.867  -0.800  -0.785  -0.773
296   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   G        -0.414  -0.410  -0.360  -0.313  -0.305  -0.226  -0.587  -0.581  -0.510
299   E        -0.414  -0.410  -0.360  -0.481  -0.474  -0.394  -0.587  -0.581  -0.510
300   T        -0.899  -0.907  -0.905  -0.664  -0.677  -0.683  -0.800  -0.807  -0.789
301   C        -0.899  -0.886  -0.889  -0.576  -0.564  -0.563  -0.800  -0.784  -0.772
302   S        -1.476  -1.473  -1.422  -1.150  -1.137  -1.063  -1.120  -1.114  -1.044
303   S        -0.899  -0.865  -0.898  -0.692  -0.635  -0.700  -0.800  -0.759  -0.781
304   V        -0.899  -0.865  -0.898  -1.008  -0.939  -1.028  -0.800  -0.759  -0.781
305   Y        -1.476  -1.473  -1.422  -1.473  -1.478  -1.385  -1.120  -1.114  -1.044
306   V        -0.323  -0.318  -0.302  -0.604  -0.595  -0.580  -0.481  -0.473  -0.440
307   I         0.830   0.839   0.710   0.742   0.757   0.525   0.798   0.812   0.579
308   A         1.870   1.878   1.923   2.039   2.049   2.124   2.076   2.089   2.158
309   M        -0.323  -0.316  -0.311  -0.136  -0.119  -0.139  -0.481  -0.470  -0.451
310   D         1.870   1.878   1.923   1.943   1.956   2.028   2.076   2.089   2.158
311   V         0.471   0.460   0.497   0.271   0.244   0.300   0.158   0.136   0.184
312   I         1.870   1.878   1.923   1.826   1.837   1.912   2.076   2.089   2.158
313   Y         1.870   1.878   1.923   2.079   2.093   2.164   2.076   2.089   2.158
314   N         1.870   1.878   1.923   1.958   1.967   2.043   2.076   2.089   2.158
315   E         1.870   1.878   1.923   1.875   1.889   1.961   2.076   2.089   2.158
316   Y         1.870   1.878   1.923   2.079   2.093   2.164   2.076   2.089   2.158
317   L         1.870   1.878   1.923   1.605   1.630   1.691   2.076   2.089   2.158
318   I         1.870   1.878   1.923   1.826   1.837   1.912   2.076   2.089   2.158
319   D        -0.899  -0.903  -0.893  -0.751  -0.756  -0.736  -0.800  -0.802  -0.776
320   P         0.830   0.797   0.707   1.133   1.089   0.961   0.798   0.743   0.573
321   F         1.870   1.878   1.923   2.031   2.043   2.117   2.076   2.089   2.158
322   L         0.471   0.460   0.497   0.029   0.021   0.076   0.158   0.136   0.184
323   K        -1.476  -1.473  -1.422  -1.238  -1.235  -1.150  -1.120  -1.114  -1.044
324   T         0.830   0.797   0.707   0.834   0.782   0.631   0.798   0.743   0.573
325   L         1.870   1.878   1.923   1.605   1.630   1.691   2.076   2.089   2.158
326   K        -0.899  -0.903  -0.893  -0.713  -0.721  -0.699  -0.800  -0.802  -0.776
327   Q        -0.899  -0.907  -0.905  -0.998  -1.016  -1.006  -0.800  -0.807  -0.789
328   L        -0.105  -0.116  -0.201  -0.373  -0.378  -0.522  -0.161  -0.174  -0.292
329   K        -0.291  -0.231  -0.279  -0.022   0.081  -0.010  -0.421  -0.336  -0.400
330   H        -1.012  -1.001  -0.958  -0.772  -0.753  -0.685  -0.920  -0.906  -0.844
331   W         0.547   0.547   0.536   0.770   0.768   0.736   0.300   0.298   0.260
332   L         0.547   0.567   0.542   0.436   0.480   0.381   0.300   0.335   0.270
333   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   T        -0.899  -0.924  -0.911  -0.887  -0.930  -0.903  -0.800  -0.825  -0.795
335   T        -1.476  -1.473  -1.422  -1.312  -1.306  -1.225  -1.120  -1.114  -1.044
336   Y        -0.899  -0.887  -0.890  -0.590  -0.574  -0.566  -0.800  -0.785  -0.773
337   N        -0.899  -0.886  -0.889  -0.777  -0.759  -0.750  -0.800  -0.784  -0.772
338   L        -0.899  -0.865  -0.898  -1.072  -1.002  -1.088  -0.800  -0.759  -0.781
339   Q        -0.105  -0.054  -0.183  -0.032   0.045  -0.154  -0.161  -0.088  -0.267
340   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   V        -0.105  -0.089  -0.191   0.045   0.066  -0.109  -0.161  -0.137  -0.279
343   L         0.830   0.815   0.701   0.676   0.671   0.522   0.798   0.773   0.563
344   V         0.830   0.858   0.718   0.879   0.920   0.698   0.798   0.844   0.593
345   G         0.471   0.460   0.497   0.457   0.434   0.492   0.158   0.136   0.184
346   I         0.830   0.815   0.701   0.842   0.820   0.657   0.798   0.773   0.563
347   H         0.471   0.488   0.514   0.504   0.529   0.573   0.158   0.189   0.216
348   L         1.870   1.878   1.923   1.605   1.630   1.691   2.076   2.089   2.158
349   R         1.870   1.878   1.923   2.064   2.081   2.150   2.076   2.089   2.158
350   S        -0.899  -0.914  -0.906  -1.104  -1.132  -1.126  -0.800  -0.815  -0.790
351   Q        -0.323  -0.316  -0.311  -0.431  -0.433  -0.406  -0.481  -0.470  -0.451
352   E        -0.105  -0.103  -0.188  -0.056  -0.055  -0.204  -0.161  -0.157  -0.274
353   V        -0.323  -0.337  -0.307  -0.508  -0.533  -0.479  -0.481  -0.494  -0.446
354   T        -0.899  -0.865  -0.898  -0.911  -0.840  -0.934  -0.800  -0.759  -0.781
355   T        -0.105  -0.070  -0.184  -0.063  -0.009  -0.186  -0.161  -0.110  -0.268
356   L        -1.476  -1.473  -1.422  -1.443  -1.431  -1.355  -1.120  -1.114  -1.044
357   F         1.870   1.878   1.923   2.031   2.043   2.117   2.076   2.089   2.158
358   L        -0.105  -0.147  -0.217  -0.373  -0.428  -0.548  -0.161  -0.219  -0.315
359   E         0.471   0.460   0.497   0.242   0.217   0.272   0.158   0.136   0.184
360   K         0.429   0.436   0.484   0.245   0.254   0.331   0.079   0.089   0.159
361   A         0.471   0.466   0.496   0.403   0.386   0.428   0.158   0.147   0.183
362   I        -0.899  -0.924  -0.911  -1.092  -1.136  -1.128  -0.800  -0.825  -0.795
363   I        -0.105  -0.129  -0.197  -0.110  -0.149  -0.252  -0.161  -0.194  -0.287
364   E         0.830   0.797   0.707   0.838   0.787   0.635   0.798   0.743   0.573
365   Y        -1.476  -1.473  -1.422  -1.071  -1.069  -0.984  -1.120  -1.114  -1.044
366   D        -1.476  -1.473  -1.422  -1.209  -1.208  -1.121  -1.120  -1.114  -1.044
367   F         0.471   0.460   0.497   0.228   0.197   0.233   0.158   0.136   0.184
368   T        -1.476  -1.473  -1.422  -1.407  -1.402  -1.319  -1.120  -1.114  -1.044
369   V         0.471   0.466   0.496   0.119   0.105   0.128   0.158   0.147   0.183
370   Y        -0.323  -0.330  -0.304  -0.122  -0.131  -0.086  -0.481  -0.486  -0.443
371   D        -0.899  -0.896  -0.886  -0.735  -0.735  -0.719  -0.800  -0.795  -0.769
372   I         0.830   0.872   0.718   0.879   0.941   0.697   0.798   0.868   0.592
373   V        -0.323  -0.300  -0.309  -0.281  -0.244  -0.255  -0.481  -0.452  -0.449
374   D         0.471   0.477   0.499   0.302   0.310   0.335   0.158   0.167   0.189
375   Q        -0.899  -0.903  -0.893  -0.599  -0.605  -0.578  -0.800  -0.802  -0.776
376   V        -0.899  -0.865  -0.898  -1.104  -1.047  -1.081  -0.800  -0.759  -0.781
377   I        -0.899  -0.887  -0.890  -0.906  -0.876  -0.859  -0.800  -0.785  -0.773
378   Q        -0.899  -0.877  -0.884  -0.861  -0.835  -0.826  -0.800  -0.773  -0.767
379   E        -0.899  -0.903  -0.893  -0.763  -0.771  -0.740  -0.800  -0.802  -0.776
380   S         0.471   0.460   0.497   0.214   0.191   0.254   0.158   0.136   0.184
381   R        -0.105  -0.147  -0.217   0.042  -0.027  -0.171  -0.161  -0.219  -0.315
382   F        -0.899  -0.924  -0.911  -0.624  -0.665  -0.635  -0.800  -0.825  -0.795
383   N        -0.899  -0.895  -0.887  -0.813  -0.808  -0.796  -0.800  -0.793  -0.769
384   F        -0.899  -0.865  -0.898  -0.891  -0.824  -0.909  -0.800  -0.759  -0.781
385   Y         0.830   0.858   0.718   0.995   1.045   0.789   0.798   0.844   0.593
386   L        -1.476  -1.473  -1.422  -1.413  -1.403  -1.325  -1.120  -1.114  -1.044
387   I        -0.323  -0.329  -0.306  -0.604  -0.613  -0.586  -0.481  -0.485  -0.445
388   T        -0.899  -0.914  -0.906  -0.723  -0.741  -0.712  -0.800  -0.815  -0.790
389   -         0.701   0.706   0.643   0.523   0.530   0.456   0.578   0.586   0.459
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12367
Output conservation file - output/Q12367
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
