1     M         1.933   1.934   1.949   2.257   2.258   2.284   2.097   2.098   2.118
2     S         1.933   1.934   1.949   1.810   1.812   1.836   2.097   2.098   2.118
3     K        -1.169  -1.169  -1.158  -0.961  -0.957  -0.941  -0.985  -0.983  -0.964
4     D         0.136   0.157   0.103  -0.263  -0.233  -0.309   0.043   0.076  -0.010
5     N        -1.169  -1.169  -1.158  -1.016  -1.013  -0.996  -0.985  -0.983  -0.964
6     R        -1.169  -1.169  -1.158  -0.974  -0.974  -0.954  -0.985  -0.983  -0.964
7     L         0.136   0.130   0.095  -0.259  -0.267  -0.315   0.043   0.034  -0.022
8     A        -0.024  -0.024  -0.011   0.082   0.083   0.105  -0.214  -0.214  -0.194
9     S        -0.024  -0.024  -0.011  -0.187  -0.186  -0.165  -0.214  -0.214  -0.194
10    I        -0.024  -0.024  -0.011   0.060   0.061   0.083  -0.214  -0.214  -0.194
11    L        -0.024  -0.024  -0.011  -0.581  -0.581  -0.560  -0.214  -0.214  -0.194
12    L        -0.024  -0.024  -0.011  -0.514  -0.514  -0.493  -0.214  -0.214  -0.194
13    Q        -0.024  -0.024  -0.011  -0.126  -0.125  -0.104  -0.214  -0.214  -0.194
14    P        -0.024  -0.024  -0.011   0.002   0.002   0.024  -0.214  -0.214  -0.194
15    V        -0.024  -0.024  -0.011  -0.065  -0.065  -0.043  -0.214  -0.214  -0.194
16    A        -0.024  -0.024  -0.011   0.046   0.046   0.068  -0.214  -0.214  -0.194
17    S        -0.024  -0.024  -0.011  -0.171  -0.171  -0.150  -0.214  -0.214  -0.194
18    S        -0.024  -0.024  -0.011  -0.065  -0.065  -0.043  -0.214  -0.214  -0.194
19    S        -0.024  -0.024  -0.011  -0.156  -0.156  -0.134  -0.214  -0.214  -0.194
20    G        -0.024  -0.024  -0.011   0.133   0.133   0.155  -0.214  -0.214  -0.194
21    N         1.933   1.934   1.949   1.914   1.916   1.940   2.097   2.098   2.118
22    C        -0.024  -0.024  -0.011  -0.296  -0.295  -0.274  -0.214  -0.214  -0.194
23    T        -0.024  -0.024  -0.011  -0.194  -0.194  -0.173  -0.214  -0.214  -0.194
24    E        -0.024  -0.024  -0.011  -0.465  -0.465  -0.444  -0.214  -0.214  -0.194
25    F         1.933   1.934   1.949   1.966   1.968   1.993   2.097   2.098   2.118
26    H        -0.024  -0.024  -0.011   0.053   0.054   0.075  -0.214  -0.214  -0.194
27    D        -0.024  -0.024  -0.011   0.118   0.119   0.141  -0.214  -0.214  -0.194
28    S         1.933   1.934   1.949   1.830   1.831   1.856   2.097   2.098   2.118
29    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    H         1.933   1.934   1.949   2.181   2.183   2.208   2.097   2.098   2.118
32    T        -0.024  -0.024  -0.011  -0.432  -0.432  -0.411  -0.214  -0.214  -0.194
33    L        -0.024  -0.024  -0.011  -0.440  -0.440  -0.419  -0.214  -0.214  -0.194
34    Q        -0.024  -0.024  -0.011   0.053   0.054   0.075  -0.214  -0.214  -0.194
35    E        -0.024  -0.024  -0.011  -0.080  -0.080  -0.058  -0.214  -0.214  -0.194
36    E        -0.024  -0.024  -0.011  -0.164  -0.163  -0.142  -0.214  -0.214  -0.194
37    L        -0.024  -0.024  -0.011  -0.473  -0.473  -0.452  -0.214  -0.214  -0.194
38    N        -0.024  -0.024  -0.011  -0.126  -0.125  -0.104  -0.214  -0.214  -0.194
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    F        -0.024  -0.024  -0.011  -0.103  -0.102  -0.081  -0.214  -0.214  -0.194
43    L         1.933   1.934   1.949   1.503   1.505   1.528   2.097   2.098   2.118
44    P         1.933   1.934   1.949   2.141   2.143   2.167   2.097   2.098   2.118
45    L        -0.024  -0.024  -0.011  -0.335  -0.335  -0.314  -0.214  -0.214  -0.194
46    E        -0.024  -0.024  -0.011  -0.225  -0.225  -0.204  -0.214  -0.214  -0.194
47    G        -0.024  -0.024  -0.011  -0.021  -0.020   0.002  -0.214  -0.214  -0.194
48    V        -0.024  -0.024  -0.011  -0.073  -0.072  -0.051  -0.214  -0.214  -0.194
49    A        -0.024  -0.024  -0.011   0.038   0.039   0.061  -0.214  -0.214  -0.194
50    S        -0.024  -0.024  -0.011  -0.202  -0.202  -0.180  -0.214  -0.214  -0.194
51    N        -0.024  -0.024  -0.011  -0.133  -0.133  -0.111  -0.214  -0.214  -0.194
52    V        -0.024  -0.024  -0.011  -0.408  -0.407  -0.386  -0.214  -0.214  -0.194
53    C        -0.024  -0.024  -0.011   0.089   0.090   0.112  -0.214  -0.214  -0.194
54    P        -0.024  -0.024  -0.011   0.031   0.032   0.053  -0.214  -0.214  -0.194
55    P        -0.024  -0.024  -0.011   0.053   0.054   0.075  -0.214  -0.214  -0.194
56    M        -0.024  -0.024  -0.011  -0.233  -0.233  -0.212  -0.214  -0.214  -0.194
57    F        -0.024  -0.024  -0.011   0.009   0.010   0.031  -0.214  -0.214  -0.194
58    R         1.933   1.934   1.949   2.049   2.051   2.075   2.097   2.098   2.118
59    G        -0.024  -0.024  -0.011   0.082   0.083   0.105  -0.214  -0.214  -0.194
60    H        -0.024  -0.024  -0.011  -0.073  -0.072  -0.051  -0.214  -0.214  -0.194
61    K        -1.169  -1.169  -1.158  -0.983  -0.982  -0.963  -0.985  -0.983  -0.964
62    N         1.933   1.934   1.949   1.927   1.928   1.953   2.097   2.098   2.118
63    Y         0.136   0.122   0.100   0.200   0.175   0.139   0.043   0.022  -0.015
64    V        -1.169  -1.169  -1.158  -1.090  -1.090  -1.071  -0.985  -0.983  -0.964
65    F        -1.169  -1.169  -1.158  -1.350  -1.352  -1.331  -0.985  -0.983  -0.964
66    V         0.136   0.130   0.095  -0.046  -0.058  -0.139   0.043   0.034  -0.022
67    L        -1.169  -1.169  -1.158  -1.295  -1.283  -1.275  -0.985  -0.983  -0.964
68    Y        -1.169  -1.169  -1.158  -0.731  -0.727  -0.710  -0.985  -0.983  -0.964
69    C        -1.169  -1.169  -1.158  -1.225  -1.231  -1.206  -0.985  -0.983  -0.964
70    L         1.933   1.934   1.949   1.514   1.516   1.539   2.097   2.098   2.118
71    N         1.933   1.934   1.949   1.927   1.928   1.953   2.097   2.098   2.118
72    Q        -1.169  -1.169  -1.158  -0.853  -0.853  -0.832  -0.985  -0.983  -0.964
73    V        -1.169  -1.169  -1.158  -0.853  -0.849  -0.832  -0.985  -0.983  -0.964
74    D        -1.169  -1.169  -1.158  -1.100  -1.100  -1.080  -0.985  -0.983  -0.964
75    L         0.136   0.130   0.095  -0.248  -0.256  -0.303   0.043   0.034  -0.022
76    V        -0.024  -0.024  -0.011  -0.090  -0.089  -0.068  -0.214  -0.214  -0.194
77    T         0.136   0.122   0.100   0.224   0.203   0.165   0.043   0.022  -0.015
78    N        -1.169  -1.169  -1.158  -1.391  -1.392  -1.372  -0.985  -0.983  -0.964
79    L        -1.169  -1.169  -1.158  -1.330  -1.319  -1.311  -0.985  -0.983  -0.964
80    Q         0.136   0.122   0.100   0.357   0.338   0.303   0.043   0.022  -0.015
81    D        -1.169  -1.169  -1.158  -1.109  -1.111  -1.090  -0.985  -0.983  -0.964
82    S         0.136   0.122   0.100   0.030   0.010  -0.024   0.043   0.022  -0.015
83    T        -1.169  -1.169  -1.158  -0.862  -0.858  -0.841  -0.985  -0.983  -0.964
84    K        -1.169  -1.169  -1.158  -0.791  -0.787  -0.771  -0.985  -0.983  -0.964
85    R        -0.024  -0.024  -0.011  -0.028  -0.027  -0.006  -0.214  -0.214  -0.194
86    Y        -0.024  -0.024  -0.011  -0.028  -0.027  -0.006  -0.214  -0.214  -0.194
87    Y        -0.024  -0.024  -0.011  -0.050  -0.050  -0.028  -0.214  -0.214  -0.194
88    P         1.933   1.934   1.949   2.141   2.143   2.167   2.097   2.098   2.118
89    L        -1.169  -1.169  -1.158  -1.162  -1.148  -1.142  -0.985  -0.983  -0.964
90    Q         0.136   0.122   0.100   0.357   0.338   0.303   0.043   0.022  -0.015
91    I        -1.169  -1.169  -1.158  -1.335  -1.341  -1.316  -0.985  -0.983  -0.964
92    F         0.136   0.122   0.100   0.196   0.174   0.138   0.043   0.022  -0.015
93    K        -1.169  -1.169  -1.158  -0.974  -0.972  -0.954  -0.985  -0.983  -0.964
94    D         0.136   0.130   0.095   0.276   0.267   0.219   0.043   0.034  -0.022
95    C         0.136   0.130   0.095   0.394   0.384   0.326   0.043   0.034  -0.022
96    Q         0.136   0.122   0.100   0.404   0.386   0.354   0.043   0.022  -0.015
97    L        -0.024  -0.024  -0.011  -0.340  -0.340  -0.319  -0.214  -0.214  -0.194
98    S        -0.024  -0.024  -0.011  -0.147  -0.146  -0.125  -0.214  -0.214  -0.194
99    S        -0.024  -0.024  -0.011  -0.188  -0.188  -0.166  -0.214  -0.214  -0.194
100   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   Q        -1.169  -1.169  -1.158  -1.002  -1.001  -0.982  -0.985  -0.983  -0.964
103   K        -1.169  -1.169  -1.158  -1.090  -1.091  -1.071  -0.985  -0.983  -0.964
104   D        -1.169  -1.169  -1.158  -1.235  -1.236  -1.216  -0.985  -0.983  -0.964
105   F         0.136   0.157   0.103   0.207   0.239   0.152   0.043   0.076  -0.010
106   S        -1.169  -1.169  -1.158  -1.100  -1.094  -1.080  -0.985  -0.983  -0.964
107   H         0.136   0.122   0.100   0.316   0.292   0.243   0.043   0.022  -0.015
108   Y         1.933   1.934   1.949   2.018   2.017   2.045   2.097   2.098   2.118
109   F         0.136   0.130   0.095  -0.031  -0.043  -0.125   0.043   0.034  -0.022
110   Q        -1.169  -1.169  -1.158  -1.315  -1.322  -1.296  -0.985  -0.983  -0.964
111   L        -0.024  -0.024  -0.011  -0.440  -0.440  -0.419  -0.214  -0.214  -0.194
112   S        -0.024  -0.024  -0.011  -0.171  -0.171  -0.150  -0.214  -0.214  -0.194
113   R        -0.024  -0.024  -0.011   0.053   0.054   0.075  -0.214  -0.214  -0.194
114   Q        -0.024  -0.024  -0.011  -0.088  -0.087  -0.066  -0.214  -0.214  -0.194
115   K        -0.024  -0.024  -0.011  -0.202  -0.202  -0.180  -0.214  -0.214  -0.194
116   E        -0.024  -0.024  -0.011  -0.050  -0.050  -0.028  -0.214  -0.214  -0.194
117   G        -0.024  -0.024  -0.011   0.211   0.212   0.234  -0.214  -0.214  -0.194
118   E        -0.024  -0.024  -0.011  -0.080  -0.080  -0.058  -0.214  -0.214  -0.194
119   D        -1.169  -1.169  -1.158  -0.993  -0.991  -0.973  -0.985  -0.983  -0.964
120   R        -1.169  -1.169  -1.158  -1.039  -1.040  -1.019  -0.985  -0.983  -0.964
121   N        -1.169  -1.169  -1.158  -1.076  -1.074  -1.057  -0.985  -0.983  -0.964
122   D         0.136   0.130   0.095   0.094   0.083   0.017   0.043   0.034  -0.022
123   S        -1.169  -1.169  -1.158  -0.988  -0.982  -0.968  -0.985  -0.983  -0.964
124   D         1.933   1.934   1.949   1.988   1.989   2.014   2.097   2.098   2.118
125   T        -1.169  -1.169  -1.158  -0.961  -0.960  -0.941  -0.985  -0.983  -0.964
126   T         1.933   1.934   1.949   2.026   2.028   2.052   2.097   2.098   2.118
127   L         1.933   1.934   1.949   1.514   1.516   1.539   2.097   2.098   2.118
128   V         1.933   1.934   1.949   1.980   1.982   2.007   2.097   2.098   2.118
129   N        -1.169  -1.169  -1.158  -1.095  -1.093  -1.075  -0.985  -0.983  -0.964
130   V        -1.169  -1.169  -1.158  -1.090  -1.090  -1.071  -0.985  -0.983  -0.964
131   V        -1.169  -1.169  -1.158  -1.030  -1.027  -1.010  -0.985  -0.983  -0.964
132   N        -1.169  -1.169  -1.158  -1.206  -1.205  -1.186  -0.985  -0.983  -0.964
133   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   G        -0.024  -0.024  -0.011   0.225   0.226   0.248  -0.214  -0.214  -0.194
135   V        -0.024  -0.024  -0.011   0.161   0.162   0.184  -0.214  -0.214  -0.194
136   S        -0.024  -0.024  -0.011  -0.103  -0.102  -0.081  -0.214  -0.214  -0.194
137   R        -0.024  -0.024  -0.011  -0.028  -0.027  -0.006  -0.214  -0.214  -0.194
138   H         1.933   1.934   1.949   2.181   2.183   2.208   2.097   2.098   2.118
139   R        -1.169  -1.169  -1.158  -1.270  -1.279  -1.250  -0.985  -0.983  -0.964
140   S         0.136   0.122   0.100   0.073   0.053   0.023   0.043   0.022  -0.015
141   Q        -0.024  -0.024  -0.011   0.078   0.078   0.100  -0.214  -0.214  -0.194
142   L        -0.024  -0.024  -0.011  -0.357  -0.357  -0.336  -0.214  -0.214  -0.194
143   L         0.136   0.157   0.103  -0.010   0.031  -0.086   0.043   0.076  -0.010
144   K        -1.169  -1.169  -1.158  -1.030  -1.029  -1.010  -0.985  -0.983  -0.964
145   M        -1.169  -1.169  -1.158  -0.774  -0.776  -0.753  -0.985  -0.983  -0.964
146   C        -1.169  -1.169  -1.158  -1.081  -1.086  -1.061  -0.985  -0.983  -0.964
147   I         0.136   0.122   0.100   0.200   0.178   0.139   0.043   0.022  -0.015
148   I        -1.169  -1.169  -1.158  -1.039  -1.038  -1.019  -0.985  -0.983  -0.964
149   P         1.933   1.934   1.949   2.205   2.208   2.232   2.097   2.098   2.118
150   R         0.136   0.122   0.100   0.048   0.020  -0.036   0.043   0.022  -0.015
151   I        -1.169  -1.169  -1.158  -1.335  -1.338  -1.316  -0.985  -0.983  -0.964
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   C         1.933   1.934   1.949   2.199   2.201   2.226   2.097   2.098   2.118
154   S        -0.024  -0.024  -0.011  -0.147  -0.146  -0.125  -0.214  -0.214  -0.194
155   F        -1.169  -1.169  -1.158  -1.350  -1.352  -1.331  -0.985  -0.983  -0.964
156   D        -1.169  -1.169  -1.158  -0.970  -0.966  -0.950  -0.985  -0.983  -0.964
157   K         0.136   0.122   0.100   0.282   0.263   0.230   0.043   0.022  -0.015
158   S        -1.169  -1.169  -1.158  -1.148  -1.143  -1.128  -0.985  -0.983  -0.964
159   N         0.136   0.122   0.100   0.119   0.097   0.061   0.043   0.022  -0.015
160   S        -1.169  -1.169  -1.158  -1.138  -1.135  -1.118  -0.985  -0.983  -0.964
161   K         0.136   0.130   0.095   0.203   0.195   0.135   0.043   0.034  -0.022
162   T        -0.024  -0.024  -0.011   0.060   0.061   0.083  -0.214  -0.214  -0.194
163   Y        -0.024  -0.024  -0.011  -0.058  -0.057  -0.036  -0.214  -0.214  -0.194
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   K        -0.024  -0.024  -0.011  -0.043  -0.042  -0.021  -0.214  -0.214  -0.194
168   L         1.933   1.934   1.949   1.503   1.505   1.528   2.097   2.098   2.118
169   I         0.136   0.130   0.095   0.293   0.284   0.234   0.043   0.034  -0.022
170   Q         0.136   0.157   0.103   0.241   0.275   0.191   0.043   0.076  -0.010
171   E         0.136   0.122   0.100   0.203   0.182   0.144   0.043   0.022  -0.015
172   Y         0.136   0.122   0.100   0.207   0.183   0.146   0.043   0.022  -0.015
173   V         0.136   0.130   0.095   0.210   0.201   0.147   0.043   0.034  -0.022
174   N         0.136   0.157   0.103   0.252   0.290   0.192   0.043   0.076  -0.010
175   R        -1.169  -1.169  -1.158  -0.929  -0.927  -0.909  -0.985  -0.983  -0.964
176   F         1.933   1.934   1.949   1.995   1.998   2.022   2.097   2.098   2.118
177   E        -1.169  -1.169  -1.158  -1.006  -1.005  -0.986  -0.985  -0.983  -0.964
178   T        -1.169  -1.169  -1.158  -0.938  -0.936  -0.918  -0.985  -0.983  -0.964
179   V         0.136   0.130   0.095   0.182   0.173   0.116   0.043   0.034  -0.022
180   L        -1.169  -1.169  -1.158  -1.090  -1.079  -1.071  -0.985  -0.983  -0.964
181   T        -1.169  -1.169  -1.158  -0.947  -0.946  -0.927  -0.985  -0.983  -0.964
182   K         0.136   0.130   0.095   0.175   0.167   0.104   0.043   0.034  -0.022
183   F         0.136   0.122   0.100   0.196   0.174   0.138   0.043   0.022  -0.015
184   G        -1.169  -1.169  -1.158  -0.924  -0.926  -0.904  -0.985  -0.983  -0.964
185   P         0.136   0.157   0.103   0.390   0.421   0.343   0.043   0.076  -0.010
186   E        -1.169  -1.169  -1.158  -0.817  -0.812  -0.797  -0.985  -0.983  -0.964
187   K         1.933   1.934   1.949   2.008   2.009   2.034   2.097   2.098   2.118
188   D        -0.024  -0.024  -0.011   0.038   0.039   0.061  -0.214  -0.214  -0.194
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   F         0.136   0.157   0.103   0.207   0.239   0.152   0.043   0.076  -0.010
194   T        -1.169  -1.169  -1.158  -1.062  -1.064  -1.042  -0.985  -0.983  -0.964
195   K        -1.169  -1.169  -1.158  -0.893  -0.889  -0.873  -0.985  -0.983  -0.964
196   V         0.136   0.130   0.095   0.182   0.173   0.116   0.043   0.034  -0.022
197   Y         1.933   1.934   1.949   2.018   2.017   2.045   2.097   2.098   2.118
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   A        -1.169  -1.169  -1.158  -0.809  -0.808  -0.788  -0.985  -0.983  -0.964
201   N         1.933   1.934   1.949   1.927   1.928   1.953   2.097   2.098   2.118
202   W         0.136   0.130   0.095   0.224   0.211   0.126   0.043   0.034  -0.022
203   S        -1.169  -1.169  -1.158  -1.350  -1.352  -1.331  -0.985  -0.983  -0.964
204   K         0.136   0.130   0.095  -0.010  -0.020  -0.103   0.043   0.034  -0.022
205   L         1.933   1.934   1.949   1.514   1.516   1.539   2.097   2.098   2.118
206   I        -1.169  -1.169  -1.158  -1.305  -1.310  -1.286  -0.985  -0.983  -0.964
207   E         0.136   0.130   0.095   0.231   0.222   0.167   0.043   0.034  -0.022
208   S         0.136   0.130   0.095   0.073   0.064   0.016   0.043   0.034  -0.022
209   F         0.136   0.157   0.103   0.207   0.239   0.152   0.043   0.076  -0.010
210   N        -1.169  -1.169  -1.158  -0.956  -0.951  -0.936  -0.985  -0.983  -0.964
211   E        -0.024  -0.024  -0.011  -0.065  -0.065  -0.043  -0.214  -0.214  -0.194
212   L        -0.024  -0.024  -0.011  -0.424  -0.424  -0.403  -0.214  -0.214  -0.194
213   I        -1.169  -1.169  -1.158  -1.310  -1.314  -1.291  -0.985  -0.983  -0.964
214   L         0.136   0.157   0.103  -0.031   0.012  -0.108   0.043   0.076  -0.010
215   H        -1.169  -1.169  -1.158  -0.997  -1.004  -0.977  -0.985  -0.983  -0.964
216   D         0.136   0.122   0.100   0.094   0.070   0.026   0.043   0.022  -0.015
217   L        -1.169  -1.169  -1.158  -1.449  -1.440  -1.430  -0.985  -0.983  -0.964
218   L         0.136   0.130   0.095  -0.244  -0.252  -0.298   0.043   0.034  -0.022
219   V         0.136   0.130   0.095   0.172   0.163   0.105   0.043   0.034  -0.022
220   K         1.933   1.934   1.949   2.008   2.009   2.034   2.097   2.098   2.118
221   W         0.136   0.130   0.095   0.440   0.428   0.368   0.043   0.034  -0.022
222   Q        -1.169  -1.169  -1.158  -0.947  -0.944  -0.927  -0.985  -0.983  -0.964
223   Q        -1.169  -1.169  -1.158  -0.947  -0.948  -0.927  -0.985  -0.983  -0.964
224   W         1.933   1.934   1.949   2.264   2.265   2.291   2.097   2.098   2.118
225   S         1.933   1.934   1.949   1.810   1.812   1.836   2.097   2.098   2.118
226   E        -0.024  -0.024  -0.011  -0.098  -0.097  -0.076  -0.214  -0.214  -0.194
227   L        -0.024  -0.024  -0.011  -0.221  -0.221  -0.200  -0.214  -0.214  -0.194
228   T        -0.024  -0.024  -0.011   0.086   0.086   0.108  -0.214  -0.214  -0.194
229   Q         1.933   1.934   1.949   2.123   2.125   2.150   2.097   2.098   2.118
230   P        -0.024  -0.024  -0.011  -0.057  -0.057  -0.035  -0.214  -0.214  -0.194
231   N         1.933   1.934   1.949   1.946   1.947   1.972   2.097   2.098   2.118
232   A        -0.024  -0.024  -0.011   0.078   0.078   0.100  -0.214  -0.214  -0.194
233   T        -0.024  -0.024  -0.011  -0.196  -0.196  -0.175  -0.214  -0.214  -0.194
234   V        -0.024  -0.024  -0.011  -0.323  -0.322  -0.301  -0.214  -0.214  -0.194
235   H        -0.024  -0.024  -0.011   0.062   0.063   0.084  -0.214  -0.214  -0.194
236   Q        -0.024  -0.024  -0.011  -0.340  -0.340  -0.319  -0.214  -0.214  -0.194
237   N         0.136   0.122   0.100   0.119   0.097   0.061   0.043   0.022  -0.015
238   I        -0.024  -0.024  -0.011   0.038   0.039   0.061  -0.214  -0.214  -0.194
239   P         0.136   0.157   0.103   0.303   0.336   0.257   0.043   0.076  -0.010
240   N        -1.169  -1.169  -1.158  -1.039  -1.037  -1.019  -0.985  -0.983  -0.964
241   V        -1.169  -1.169  -1.158  -1.330  -1.331  -1.311  -0.985  -0.983  -0.964
242   L        -1.169  -1.169  -1.158  -1.443  -1.435  -1.424  -0.985  -0.983  -0.964
243   R         0.136   0.122   0.100   0.276   0.254   0.216   0.043   0.022  -0.015
244   E        -1.169  -1.169  -1.158  -1.034  -1.035  -1.014  -0.985  -0.983  -0.964
245   L         0.136   0.130   0.095  -0.256  -0.264  -0.311   0.043   0.034  -0.022
246   V        -1.169  -1.169  -1.158  -1.335  -1.338  -1.316  -0.985  -0.983  -0.964
247   I        -1.169  -1.169  -1.158  -1.330  -1.333  -1.311  -0.985  -0.983  -0.964
248   K         0.136   0.130   0.095   0.245   0.237   0.181   0.043   0.034  -0.022
249   L         0.136   0.130   0.095  -0.352  -0.362  -0.419   0.043   0.034  -0.022
250   T        -1.169  -1.169  -1.158  -1.305  -1.307  -1.286  -0.985  -0.983  -0.964
251   Q         0.136   0.122   0.100   0.337   0.317   0.280   0.043   0.022  -0.015
252   R         0.136   0.122   0.100   0.231   0.208   0.166   0.043   0.022  -0.015
253   Y         1.933   1.934   1.949   2.018   2.017   2.045   2.097   2.098   2.118
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   F        -1.169  -1.169  -1.158  -1.325  -1.332  -1.306  -0.985  -0.983  -0.964
258   T         0.136   0.122   0.100   0.224   0.203   0.165   0.043   0.022  -0.015
259   F         0.136   0.122   0.100  -0.031  -0.058  -0.114   0.043   0.022  -0.015
260   Q        -0.024  -0.024  -0.011   0.078   0.078   0.100  -0.214  -0.214  -0.194
261   P        -0.024  -0.024  -0.011   0.109   0.110   0.131  -0.214  -0.214  -0.194
262   S         0.136   0.130   0.095   0.027   0.018  -0.036   0.043   0.034  -0.022
263   Y        -1.169  -1.169  -1.158  -0.911  -0.912  -0.891  -0.985  -0.983  -0.964
264   S         0.136   0.122   0.100   0.066   0.048   0.015   0.043   0.022  -0.015
265   C         0.136   0.122   0.100   0.367   0.343   0.304   0.043   0.022  -0.015
266   S         0.136   0.130   0.095   0.012   0.003  -0.052   0.043   0.034  -0.022
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   I         1.933   1.934   1.949   2.018   2.020   2.045   2.097   2.098   2.118
269   D         1.933   1.934   1.949   1.988   1.989   2.014   2.097   2.098   2.118
270   E        -1.169  -1.169  -1.158  -1.016  -1.012  -0.996  -0.985  -0.983  -0.964
271   F         1.933   1.934   1.949   1.995   1.998   2.022   2.097   2.098   2.118
272   T         1.933   1.934   1.949   2.026   2.028   2.052   2.097   2.098   2.118
273   T         0.136   0.130   0.095   0.217   0.208   0.149   0.043   0.034  -0.022
274   I        -1.169  -1.169  -1.158  -1.025  -1.024  -1.005  -0.985  -0.983  -0.964
275   L         1.933   1.934   1.949   1.514   1.516   1.539   2.097   2.098   2.118
276   L        -1.169  -1.169  -1.158  -1.330  -1.319  -1.311  -0.985  -0.983  -0.964
277   N         0.136   0.130   0.095   0.231   0.223   0.177   0.043   0.034  -0.022
278   K        -0.024  -0.024  -0.011  -0.041  -0.041  -0.019  -0.214  -0.214  -0.194
279   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   L         1.933   1.934   1.949   1.503   1.505   1.528   2.097   2.098   2.118
282   S        -0.024  -0.024  -0.011  -0.194  -0.194  -0.173  -0.214  -0.214  -0.194
283   L        -1.169  -1.169  -1.158  -1.048  -1.034  -1.028  -0.985  -0.983  -0.964
284   L         1.933   1.934   1.949   1.514   1.516   1.539   2.097   2.098   2.118
285   D        -1.169  -1.169  -1.158  -1.039  -1.037  -1.019  -0.985  -0.983  -0.964
286   V        -1.169  -1.169  -1.158  -1.025  -1.025  -1.005  -0.985  -0.983  -0.964
287   F        -1.169  -1.169  -1.158  -0.956  -0.956  -0.936  -0.985  -0.983  -0.964
288   R        -1.169  -1.169  -1.158  -1.148  -1.150  -1.128  -0.985  -0.983  -0.964
289   K         0.136   0.122   0.100   0.123   0.100   0.054   0.043   0.022  -0.015
290   P        -0.024  -0.024  -0.011   0.101   0.102   0.124  -0.214  -0.214  -0.194
291   R         1.933   1.934   1.949   2.123   2.125   2.150   2.097   2.098   2.118
292   K         1.933   1.934   1.949   1.934   1.936   1.961   2.097   2.098   2.118
293   Y        -0.024  -0.024  -0.011   0.062   0.063   0.084  -0.214  -0.214  -0.194
294   K        -0.024  -0.024  -0.011  -0.106  -0.105  -0.084  -0.214  -0.214  -0.194
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -0.024  -0.024  -0.011  -0.100  -0.100  -0.078  -0.214  -0.214  -0.194
302   -        -0.024  -0.024  -0.011  -0.143  -0.142  -0.121  -0.214  -0.214  -0.194
303   -        -0.024  -0.024  -0.011  -0.109  -0.108  -0.087  -0.214  -0.214  -0.194
304   -         1.933   1.934   1.949   1.930   1.932   1.957   2.097   2.098   2.118
305   -        -0.024  -0.024  -0.011   0.107   0.107   0.129  -0.214  -0.214  -0.194
306   -        -0.024  -0.024  -0.011  -0.109  -0.108  -0.087  -0.214  -0.214  -0.194
307   L         1.933   1.934   1.949   1.514   1.516   1.539   2.097   2.098   2.118
308   N         0.136   0.130   0.095   0.137   0.128   0.072   0.043   0.034  -0.022
309   F         0.136   0.157   0.103   0.207   0.239   0.152   0.043   0.076  -0.010
310   G         1.933   1.934   1.949   2.161   2.161   2.188   2.097   2.098   2.118
311   L         0.136   0.157   0.103  -0.010   0.033  -0.086   0.043   0.076  -0.010
312   W         1.933   1.934   1.949   2.264   2.265   2.291   2.097   2.098   2.118
313   L        -1.169  -1.169  -1.158  -1.325  -1.314  -1.306  -0.985  -0.983  -0.964
314   D         0.136   0.130   0.095   0.147   0.137   0.076   0.043   0.034  -0.022
315   C        -1.169  -1.169  -1.158  -1.138  -1.148  -1.118  -0.985  -0.983  -0.964
316   Q        -1.169  -1.169  -1.158  -1.086  -1.088  -1.066  -0.985  -0.983  -0.964
317   N         0.136   0.130   0.095   0.231   0.223   0.177   0.043   0.034  -0.022
318   G         1.933   1.934   1.949   2.161   2.161   2.188   2.097   2.098   2.118
319   I         0.136   0.130   0.095  -0.010  -0.022  -0.103   0.043   0.034  -0.022
320   L        -1.169  -1.169  -1.158  -1.335  -1.325  -1.316  -0.985  -0.983  -0.964
321   I         0.136   0.157   0.103  -0.248  -0.217  -0.292   0.043   0.076  -0.010
322   F         0.136   0.130   0.095  -0.031  -0.043  -0.125   0.043   0.034  -0.022
323   T        -1.169  -1.169  -1.158  -0.897  -0.895  -0.877  -0.985  -0.983  -0.964
324   N         1.933   1.934   1.949   1.927   1.928   1.953   2.097   2.098   2.118
325   G         0.136   0.122   0.100   0.420   0.399   0.366   0.043   0.022  -0.015
326   I         0.136   0.122   0.100   0.210   0.188   0.150   0.043   0.022  -0.015
327   V        -1.169  -1.169  -1.158  -1.270  -1.275  -1.250  -0.985  -0.983  -0.964
328   Q        -1.169  -1.169  -1.158  -0.769  -0.767  -0.749  -0.985  -0.983  -0.964
329   M        -1.169  -1.169  -1.158  -0.920  -0.925  -0.900  -0.985  -0.983  -0.964
330   A        -1.169  -1.169  -1.158  -0.791  -0.792  -0.771  -0.985  -0.983  -0.964
331   D         0.136   0.122   0.100   0.189   0.167   0.131   0.043   0.022  -0.015
332   E         0.136   0.130   0.095  -0.024  -0.036  -0.118   0.043   0.034  -0.022
333   I         0.136   0.157   0.103  -0.248  -0.217  -0.292   0.043   0.076  -0.010
334   T        -1.169  -1.169  -1.158  -1.002  -1.000  -0.982  -0.985  -0.983  -0.964
335   S        -0.024  -0.024  -0.011  -0.188  -0.188  -0.166  -0.214  -0.214  -0.194
336   E        -0.024  -0.024  -0.011   0.140   0.141   0.162  -0.214  -0.214  -0.194
337   R        -0.024  -0.024  -0.011  -0.041  -0.041  -0.019  -0.214  -0.214  -0.194
338   V        -0.024  -0.024  -0.011  -0.542  -0.542  -0.521  -0.214  -0.214  -0.194
339   K        -0.024  -0.024  -0.011   0.062   0.063   0.084  -0.214  -0.214  -0.194
340   S         1.933   1.934   1.949   1.809   1.811   1.835   2.097   2.098   2.118
341   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   R        -0.024  -0.024  -0.011  -0.043  -0.042  -0.021  -0.214  -0.214  -0.194
344   P         1.933   1.934   1.949   2.141   2.143   2.167   2.097   2.098   2.118
345   A         0.136   0.157   0.103   0.073   0.103   0.027   0.043   0.076  -0.010
346   H         0.136   0.122   0.100   0.397   0.375   0.333   0.043   0.022  -0.015
347   L        -1.169  -1.169  -1.158  -1.350  -1.340  -1.331  -0.985  -0.983  -0.964
348   L        -1.169  -1.169  -1.158  -1.245  -1.236  -1.226  -0.985  -0.983  -0.964
349   V        -1.169  -1.169  -1.158  -0.875  -0.869  -0.855  -0.985  -0.983  -0.964
350   L        -1.169  -1.169  -1.158  -1.371  -1.360  -1.352  -0.985  -0.983  -0.964
351   E         0.136   0.157   0.103   0.182   0.216   0.128   0.043   0.076  -0.010
352   D         0.136   0.122   0.100   0.182   0.160   0.123   0.043   0.022  -0.015
353   H        -0.024  -0.024  -0.011  -0.230  -0.229  -0.208  -0.214  -0.214  -0.194
354   S        -1.169  -1.169  -1.158  -1.067  -1.059  -1.047  -0.985  -0.983  -0.964
355   N         0.136   0.157   0.103   0.175   0.211   0.117   0.043   0.076  -0.010
356   D         0.136   0.130   0.095   0.193   0.183   0.127   0.043   0.034  -0.022
357   E        -1.169  -1.169  -1.158  -1.340  -1.343  -1.321  -0.985  -0.983  -0.964
358   A        -1.169  -1.169  -1.158  -1.260  -1.268  -1.241  -0.985  -0.983  -0.964
359   V         1.933   1.934   1.949   1.980   1.982   2.007   2.097   2.098   2.118
360   K        -1.169  -1.169  -1.158  -0.961  -0.958  -0.941  -0.985  -0.983  -0.964
361   K         1.933   1.934   1.949   2.018   2.021   2.045   2.097   2.098   2.118
362   L         0.136   0.130   0.095  -0.248  -0.257  -0.303   0.043   0.034  -0.022
363   M         0.136   0.122   0.100   0.217   0.188   0.130   0.043   0.022  -0.015
364   F        -1.169  -1.169  -1.158  -1.350  -1.352  -1.331  -0.985  -0.983  -0.964
365   F         1.933   1.934   1.949   1.995   1.998   2.022   2.097   2.098   2.118
366   T         0.136   0.157   0.103   0.370   0.406   0.313   0.043   0.076  -0.010
367   F         0.136   0.157   0.103   0.123   0.157   0.069   0.043   0.076  -0.010
368   S         0.136   0.157   0.103   0.343   0.383   0.276   0.043   0.076  -0.010
369   A         0.136   0.157   0.103   0.073   0.103   0.027   0.043   0.076  -0.010
370   I        -1.169  -1.169  -1.158  -1.335  -1.341  -1.316  -0.985  -0.983  -0.964
371   L         0.136   0.122   0.100  -0.267  -0.286  -0.317   0.043   0.022  -0.015
372   Q         0.136   0.157   0.103   0.241   0.275   0.191   0.043   0.076  -0.010
373   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   C         1.933   1.934   1.949   2.183   2.185   2.210   2.097   2.098   2.118
375   F         0.136   0.157   0.103  -0.259  -0.228  -0.305   0.043   0.076  -0.010
376   T        -1.169  -1.169  -1.158  -0.709  -0.705  -0.689  -0.985  -0.983  -0.964
377   D        -0.024  -0.024  -0.011  -0.001  -0.001   0.021  -0.214  -0.214  -0.194
378   E         1.933   1.934   1.949   2.046   2.048   2.073   2.097   2.098   2.118
379   I        -0.024  -0.024  -0.011  -0.017  -0.017   0.005  -0.214  -0.214  -0.194
380   L        -0.024  -0.024  -0.011  -0.587  -0.587  -0.567  -0.214  -0.214  -0.194
381   N        -0.024  -0.024  -0.011  -0.049  -0.049  -0.027  -0.214  -0.214  -0.194
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   -         1.933   1.934   1.949   2.023   2.025   2.050   2.097   2.098   2.118
384   C        -1.169  -1.169  -1.158  -1.039  -1.043  -1.019  -0.985  -0.983  -0.964
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12366
Output conservation file - output/Q12366
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
