1     M         2.029   2.040   2.111   2.313   2.330   2.444   2.287   2.303   2.421
2     I        -0.859  -0.842  -0.846  -0.816  -0.784  -0.809  -0.784  -0.762  -0.748
3     F         0.810   0.832   0.775   0.712   0.745   0.666   0.688   0.724   0.602
4     N         0.649   0.634   0.665   0.437   0.401   0.437   0.391   0.360   0.391
5     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    S         0.944   0.972   0.858   0.906   0.948   0.783   0.922   0.968   0.754
15    L        -0.859  -0.891  -0.876  -0.928  -0.977  -0.939  -0.784  -0.817  -0.781
16    I        -0.859  -0.828  -0.850  -1.063  -1.013  -1.053  -0.784  -0.745  -0.753
17    W        -0.859  -0.838  -0.840  -0.510  -0.480  -0.476  -0.784  -0.757  -0.742
18    A        -0.258  -0.224  -0.225  -0.558  -0.514  -0.497  -0.442  -0.402  -0.386
19    M        -0.031  -0.021  -0.103  -0.073  -0.068  -0.174  -0.101  -0.088  -0.201
20    E        -0.859  -0.838  -0.840  -0.861  -0.828  -0.820  -0.784  -0.757  -0.742
21    P        -0.258  -0.250  -0.239  -0.348  -0.345  -0.316  -0.442  -0.430  -0.402
22    -        -0.225  -0.210  -0.215  -0.350  -0.313  -0.351  -0.379  -0.356  -0.361
23    S        -0.859  -0.871  -0.855  -0.843  -0.849  -0.821  -0.784  -0.795  -0.759
24    F        -0.258  -0.253  -0.227  -0.360  -0.358  -0.315  -0.442  -0.435  -0.389
25    V         2.029   2.040   2.111   1.923   1.938   2.049   2.287   2.303   2.421
26    R        -1.460  -1.456  -1.409  -1.102  -1.082  -1.013  -1.125  -1.117  -1.046
27    G        -0.031  -0.021  -0.103   0.083   0.092  -0.035  -0.101  -0.088  -0.201
28    K         0.944   0.952   0.845   0.993   1.004   0.855   0.922   0.934   0.730
29    N         0.944   0.952   0.845   1.031   1.043   0.893   0.922   0.934   0.730
30    V         0.944   0.972   0.858   0.863   0.903   0.729   0.922   0.968   0.754
31    V        -0.258  -0.250  -0.239  -0.564  -0.548  -0.533  -0.442  -0.430  -0.402
32    N        -0.859  -0.882  -0.858  -0.835  -0.876  -0.833  -0.784  -0.807  -0.762
33    L        -0.031  -0.028  -0.100  -0.051  -0.049  -0.142  -0.101  -0.097  -0.197
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    I        -0.225  -0.254  -0.241  -0.323  -0.361  -0.351  -0.379  -0.419  -0.398
60    T        -0.225  -0.254  -0.241  -0.223  -0.280  -0.283  -0.379  -0.419  -0.398
61    F        -0.225  -0.254  -0.241  -0.138  -0.187  -0.189  -0.379  -0.419  -0.398
62    K        -0.225  -0.181  -0.213  -0.372  -0.301  -0.352  -0.379  -0.315  -0.359
63    D         0.944   0.901   0.837   0.919   0.858   0.770   0.922   0.846   0.716
64    S        -0.859  -0.882  -0.858  -0.915  -0.946  -0.906  -0.784  -0.807  -0.762
65    N        -0.859  -0.891  -0.876  -0.764  -0.808  -0.779  -0.784  -0.817  -0.781
66    G        -0.859  -0.891  -0.876  -0.794  -0.852  -0.843  -0.784  -0.817  -0.781
67    K        -0.031  -0.083  -0.132   0.072  -0.003  -0.062  -0.101  -0.175  -0.244
68    L         0.570   0.562   0.609   0.244   0.229   0.298   0.240   0.222   0.282
69    H         0.570   0.562   0.609   0.611   0.590   0.650   0.240   0.222   0.282
70    K         0.944   0.972   0.858   0.993   1.031   0.876   0.922   0.968   0.754
71    R         2.029   2.040   2.111   2.191   2.211   2.320   2.287   2.303   2.421
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    L         0.810   0.753   0.746   0.738   0.662   0.654   0.688   0.583   0.546
79    A        -0.225  -0.254  -0.241  -0.281  -0.332  -0.332  -0.379  -0.419  -0.398
80    P        -0.225  -0.254  -0.241  -0.246  -0.306  -0.309  -0.379  -0.419  -0.398
81    E         0.810   0.753   0.746   0.811   0.721   0.712   0.688   0.583   0.546
82    E        -0.225  -0.254  -0.241  -0.326  -0.383  -0.358  -0.379  -0.419  -0.398
83    I        -0.225  -0.243  -0.222  -0.303  -0.347  -0.298  -0.379  -0.405  -0.372
84    -        -0.353  -0.348  -0.292  -0.333  -0.331  -0.234  -0.556  -0.549  -0.469
85    -        -0.353  -0.348  -0.292  -0.422  -0.414  -0.324  -0.556  -0.549  -0.469
86    -         0.649   0.642   0.669   0.586   0.568   0.589   0.391   0.374   0.400
87    -         0.649   0.648   0.674   0.709   0.703   0.723   0.391   0.386   0.408
88    -        -0.353  -0.348  -0.292  -0.758  -0.746  -0.664  -0.556  -0.549  -0.469
89    -        -0.353  -0.348  -0.292  -0.558  -0.547  -0.461  -0.556  -0.549  -0.469
90    -        -0.353  -0.348  -0.292  -0.422  -0.414  -0.324  -0.556  -0.549  -0.469
91    -        -0.353  -0.348  -0.292  -0.384  -0.384  -0.286  -0.556  -0.549  -0.469
92    -         0.649   0.679   0.683   0.412   0.468   0.447   0.391   0.445   0.426
93    P        -0.225  -0.181  -0.213  -0.326  -0.258  -0.309  -0.379  -0.315  -0.359
94    P         0.810   0.852   0.778   0.966   1.036   0.917   0.688   0.760   0.606
95    R        -0.976  -0.970  -0.921  -1.140  -1.127  -1.051  -0.912  -0.902  -0.830
96    L        -0.258  -0.263  -0.238  -0.441  -0.436  -0.394  -0.442  -0.445  -0.400
97    H        -1.460  -1.456  -1.409  -1.127  -1.135  -1.038  -1.125  -1.117  -1.046
98    N        -0.859  -0.858  -0.841  -0.743  -0.736  -0.704  -0.784  -0.779  -0.743
99    S        -0.859  -0.815  -0.852  -0.960  -0.888  -0.944  -0.784  -0.731  -0.755
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   Q        -0.859  -0.871  -0.855  -0.701  -0.723  -0.702  -0.784  -0.795  -0.759
118   V        -0.859  -0.863  -0.854  -0.966  -0.962  -0.953  -0.784  -0.787  -0.758
119   N        -0.031  -0.028  -0.100   0.054   0.059  -0.048  -0.101  -0.097  -0.197
120   S        -0.859  -0.828  -0.850  -0.802  -0.751  -0.768  -0.784  -0.745  -0.753
121   Y        -0.859  -0.871  -0.855  -0.580  -0.604  -0.579  -0.784  -0.795  -0.759
122   P        -0.031  -0.066  -0.130   0.189   0.133   0.026  -0.101  -0.150  -0.240
123   L        -0.258  -0.264  -0.228  -0.326  -0.320  -0.260  -0.442  -0.447  -0.390
124   G        -0.859  -0.852  -0.853  -0.939  -0.932  -0.923  -0.784  -0.774  -0.757
125   Y        -0.859  -0.863  -0.854  -0.806  -0.823  -0.779  -0.784  -0.787  -0.758
126   K        -0.859  -0.838  -0.840  -0.918  -0.878  -0.879  -0.784  -0.757  -0.742
127   G        -0.258  -0.263  -0.238  -0.328  -0.338  -0.303  -0.442  -0.445  -0.400
128   M        -1.460  -1.456  -1.409  -1.311  -1.309  -1.224  -1.125  -1.117  -1.046
129   R        -0.859  -0.882  -0.858  -0.623  -0.658  -0.617  -0.784  -0.807  -0.762
130   D        -0.859  -0.871  -0.855  -0.969  -0.993  -0.960  -0.784  -0.795  -0.759
131   F        -0.859  -0.852  -0.853  -0.798  -0.793  -0.770  -0.784  -0.774  -0.757
132   S        -0.258  -0.243  -0.232  -0.502  -0.479  -0.454  -0.442  -0.423  -0.394
133   R         0.570   0.557   0.609   0.563   0.540   0.617   0.240   0.211   0.282
134   P         0.570   0.562   0.609   0.441   0.418   0.475   0.240   0.222   0.282
135   A        -1.460  -1.456  -1.409  -1.341  -1.332  -1.254  -1.125  -1.117  -1.046
136   V        -0.258  -0.243  -0.232  -0.278  -0.250  -0.214  -0.442  -0.423  -0.394
137   N        -0.859  -0.863  -0.854  -0.825  -0.837  -0.835  -0.784  -0.787  -0.758
138   L        -1.460  -1.456  -1.409  -1.057  -1.028  -0.967  -1.125  -1.117  -1.046
139   D        -0.859  -0.828  -0.850  -0.831  -0.773  -0.835  -0.784  -0.745  -0.753
140   D        -0.031  -0.066  -0.130  -0.037  -0.092  -0.176  -0.101  -0.150  -0.240
141   I        -0.031   0.002  -0.095  -0.171  -0.122  -0.287  -0.101  -0.055  -0.190
142   L        -0.225  -0.236  -0.222  -0.511  -0.531  -0.518  -0.379  -0.394  -0.372
143   G        -0.225  -0.216  -0.213  -0.353  -0.340  -0.330  -0.379  -0.364  -0.359
144   T        -0.225  -0.216  -0.213  -0.214  -0.200  -0.186  -0.379  -0.364  -0.359
145   Q        -0.225  -0.218  -0.203  -0.067  -0.055  -0.029  -0.379  -0.367  -0.345
146   Q        -0.225  -0.236  -0.222  -0.204  -0.227  -0.216  -0.379  -0.394  -0.372
147   R        -0.976  -0.974  -0.921  -0.825  -0.822  -0.733  -0.912  -0.906  -0.830
148   K         0.649   0.634   0.665   0.651   0.630   0.682   0.391   0.360   0.391
149   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   E        -0.976  -0.974  -0.921  -1.212  -1.210  -1.124  -0.912  -0.906  -0.830
156   L        -0.976  -0.974  -0.921  -1.118  -1.108  -1.029  -0.912  -0.906  -0.830
157   S        -1.460  -1.456  -1.409  -1.164  -1.137  -1.076  -1.125  -1.117  -1.046
158   P        -0.859  -0.871  -0.855  -0.640  -0.652  -0.633  -0.784  -0.795  -0.759
159   L        -1.460  -1.456  -1.409  -1.501  -1.484  -1.416  -1.125  -1.117  -1.046
160   S        -0.859  -0.852  -0.853  -0.743  -0.729  -0.756  -0.784  -0.774  -0.757
161   L         2.029   2.040   2.111   1.908   1.925   2.034   2.287   2.303   2.421
162   E        -0.859  -0.863  -0.854  -0.812  -0.813  -0.786  -0.784  -0.787  -0.758
163   S         0.944   0.929   0.845   0.923   0.905   0.787   0.922   0.895   0.730
164   K        -1.460  -1.456  -1.409  -1.226  -1.219  -1.138  -1.125  -1.117  -1.046
165   L         0.944   0.972   0.858   0.848   0.890   0.714   0.922   0.968   0.754
166   S        -0.859  -0.891  -0.876  -0.897  -0.938  -0.909  -0.784  -0.817  -0.781
167   L        -0.859  -0.815  -0.852  -0.841  -0.756  -0.851  -0.784  -0.731  -0.755
168   V        -0.031   0.002  -0.095  -0.206  -0.152  -0.326  -0.101  -0.055  -0.190
169   N        -0.859  -0.828  -0.850  -0.599  -0.546  -0.579  -0.784  -0.745  -0.753
170   E        -0.859  -0.891  -0.876  -0.861  -0.917  -0.896  -0.784  -0.817  -0.781
171   V        -0.031   0.036  -0.098  -0.116  -0.006  -0.246  -0.101  -0.004  -0.194
172   Q        -0.859  -0.842  -0.846  -0.863  -0.838  -0.831  -0.784  -0.762  -0.748
173   I         0.944   0.952   0.845   0.922   0.933   0.754   0.922   0.934   0.730
174   F         2.029   2.040   2.111   2.247   2.265   2.378   2.287   2.303   2.421
175   A        -0.031  -0.066  -0.130   0.084   0.034  -0.080  -0.101  -0.150  -0.240
176   S        -0.258  -0.250  -0.239  -0.367  -0.342  -0.320  -0.442  -0.430  -0.402
177   Y         2.029   2.040   2.111   2.299   2.319   2.430   2.287   2.303   2.421
178   V        -1.460  -1.456  -1.409  -1.564  -1.552  -1.481  -1.125  -1.117  -1.046
179   R         2.029   2.040   2.111   2.191   2.211   2.320   2.287   2.303   2.421
180   N         0.570   0.601   0.639   0.265   0.318   0.372   0.240   0.297   0.341
181   D         0.944   0.952   0.845   0.852   0.863   0.686   0.922   0.934   0.730
182   V        -0.859  -0.842  -0.846  -0.713  -0.674  -0.695  -0.784  -0.762  -0.748
183   E         0.944   0.972   0.858   1.005   1.047   0.870   0.922   0.968   0.754
184   T        -0.859  -0.815  -0.852  -1.012  -0.945  -0.999  -0.784  -0.731  -0.755
185   Y        -0.859  -0.891  -0.876  -0.680  -0.738  -0.735  -0.784  -0.817  -0.781
186   N        -1.460  -1.456  -1.409  -1.313  -1.294  -1.227  -1.125  -1.117  -1.046
187   K        -0.859  -0.858  -0.841  -0.650  -0.649  -0.601  -0.784  -0.779  -0.743
188   V        -1.460  -1.456  -1.409  -1.192  -1.178  -1.104  -1.125  -1.117  -1.046
189   S        -1.460  -1.456  -1.409  -1.346  -1.329  -1.260  -1.125  -1.117  -1.046
190   D         2.029   2.040   2.111   1.933   1.947   2.059   2.287   2.303   2.421
191   P        -0.859  -0.891  -0.876  -0.650  -0.704  -0.680  -0.784  -0.817  -0.781
192   N        -1.460  -1.456  -1.409  -1.548  -1.546  -1.464  -1.125  -1.117  -1.046
193   E        -0.258  -0.224  -0.231  -0.346  -0.295  -0.296  -0.442  -0.402  -0.393
194   D        -0.859  -0.891  -0.876  -0.878  -0.923  -0.886  -0.784  -0.817  -0.781
195   L        -0.031  -0.083  -0.132   0.006  -0.060  -0.114  -0.101  -0.175  -0.244
196   I         0.944   0.929   0.845   0.926   0.901   0.760   0.922   0.895   0.730
197   I         0.570   0.577   0.613   0.234   0.243   0.291   0.240   0.250   0.290
198   I         0.944   0.929   0.845   0.922   0.898   0.755   0.922   0.895   0.730
199   A         2.029   2.040   2.111   2.119   2.136   2.248   2.287   2.303   2.421
200   P         2.029   2.040   2.111   2.210   2.228   2.340   2.287   2.303   2.421
201   T         0.570   0.557   0.609   0.423   0.387   0.458   0.240   0.211   0.282
202   N         0.944   0.901   0.837   0.967   0.899   0.789   0.922   0.846   0.716
203   R        -0.258  -0.224  -0.231  -0.371  -0.329  -0.315  -0.442  -0.402  -0.393
204   A         0.944   0.901   0.837   1.041   0.976   0.862   0.922   0.846   0.716
205   V         0.570   0.586   0.624   0.258   0.286   0.331   0.240   0.268   0.311
206   S        -0.031  -0.028  -0.100  -0.029  -0.024  -0.123  -0.101  -0.097  -0.197
207   Q        -0.859  -0.815  -0.852  -0.861  -0.801  -0.837  -0.784  -0.731  -0.755
208   L         0.944   0.901   0.837   0.848   0.785   0.680   0.922   0.846   0.716
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   T        -0.859  -0.852  -0.853  -0.780  -0.774  -0.774  -0.784  -0.774  -0.757
212   L        -0.031  -0.010  -0.095  -0.051  -0.017  -0.135  -0.101  -0.070  -0.191
213   K         2.029   2.040   2.111   2.007   2.020   2.134   2.287   2.303   2.421
214   P         2.029   2.040   2.111   2.210   2.228   2.340   2.287   2.303   2.421
215   W         2.029   2.040   2.111   2.387   2.404   2.519   2.287   2.303   2.421
216   Q         0.944   0.901   0.837   1.161   1.095   0.995   0.922   0.846   0.716
217   F         2.029   2.040   2.111   2.247   2.265   2.378   2.287   2.303   2.421
218   P         2.029   2.040   2.111   2.210   2.228   2.340   2.287   2.303   2.421
219   N         0.944   0.972   0.858   1.062   1.099   0.957   0.922   0.968   0.754
220   N        -0.859  -0.882  -0.858  -0.863  -0.899  -0.865  -0.784  -0.807  -0.762
221   I         0.944   0.901   0.837   0.922   0.853   0.741   0.922   0.846   0.716
222   D         2.029   2.040   2.111   1.916   1.927   2.043   2.287   2.303   2.421
223   K        -0.353  -0.346  -0.292  -0.395  -0.384  -0.297  -0.556  -0.546  -0.469
224   L         0.649   0.682   0.669   0.676   0.741   0.676   0.391   0.450   0.400
225   E         2.029   2.040   2.111   2.042   2.059   2.170   2.287   2.303   2.421
226   S         0.649   0.682   0.669   0.645   0.708   0.651   0.391   0.450   0.400
227   D        -0.859  -0.815  -0.852  -0.798  -0.716  -0.800  -0.784  -0.731  -0.755
228   G         0.944   0.952   0.845   1.128   1.141   0.973   0.922   0.934   0.730
229   A        -0.859  -0.882  -0.858  -0.855  -0.895  -0.867  -0.784  -0.807  -0.762
230   T        -0.031   0.020  -0.098  -0.047   0.029  -0.142  -0.101  -0.027  -0.195
231   E         0.810   0.792   0.748   0.857   0.839   0.758   0.688   0.654   0.550
232   K         0.810   0.846   0.766   0.840   0.897   0.770   0.688   0.750   0.584
233   E        -0.031   0.020  -0.098  -0.043   0.032  -0.137  -0.101  -0.027  -0.195
234   L        -0.859  -0.863  -0.854  -1.014  -1.025  -1.020  -0.784  -0.787  -0.758
235   D         2.029   2.040   2.111   1.933   1.947   2.059   2.287   2.303   2.421
236   T        -1.460  -1.456  -1.409  -1.286  -1.276  -1.199  -1.125  -1.117  -1.046
237   A        -0.031  -0.083  -0.132   0.019  -0.069  -0.171  -0.101  -0.175  -0.244
238   I        -0.031  -0.083  -0.132  -0.048  -0.136  -0.220  -0.101  -0.175  -0.244
239   Q        -1.460  -1.456  -1.409  -1.259  -1.270  -1.172  -1.125  -1.117  -1.046
240   E         0.944   0.972   0.858   1.014   1.056   0.883   0.922   0.968   0.754
241   N         2.029   2.040   2.111   2.046   2.060   2.174   2.287   2.303   2.421
242   I        -0.031  -0.066  -0.130  -0.116  -0.179  -0.306  -0.101  -0.150  -0.240
243   S        -0.859  -0.871  -0.855  -0.986  -1.004  -0.980  -0.784  -0.795  -0.759
244   K        -0.859  -0.838  -0.840  -0.798  -0.766  -0.764  -0.784  -0.757  -0.742
245   F         2.029   2.040   2.111   2.247   2.265   2.378   2.287   2.303   2.421
246   V         0.944   0.901   0.837   0.838   0.771   0.658   0.922   0.846   0.716
247   R        -0.859  -0.891  -0.876  -0.721  -0.775  -0.759  -0.784  -0.817  -0.781
248   S        -0.031  -0.083  -0.132  -0.054  -0.130  -0.204  -0.101  -0.175  -0.244
249   H         2.029   2.040   2.111   2.322   2.340   2.454   2.287   2.303   2.421
250   I         0.570   0.594   0.625   0.234   0.275   0.313   0.240   0.283   0.312
251   V         0.944   0.901   0.837   0.863   0.798   0.694   0.922   0.846   0.716
252   V         0.570   0.583   0.623   0.300   0.320   0.380   0.240   0.261   0.309
253   Y        -0.258  -0.250  -0.239  -0.195  -0.196  -0.151  -0.442  -0.430  -0.402
254   N        -1.460  -1.456  -1.409  -1.209  -1.193  -1.121  -1.125  -1.117  -1.046
255   D        -0.258  -0.264  -0.228  -0.444  -0.450  -0.381  -0.442  -0.447  -0.390
256   D         0.944   0.929   0.845   0.848   0.824   0.681   0.922   0.895   0.730
257   K        -0.859  -0.858  -0.841  -0.794  -0.797  -0.756  -0.784  -0.779  -0.743
258   N        -1.460  -1.456  -1.409  -1.313  -1.295  -1.227  -1.125  -1.117  -1.046
259   S         0.649   0.689   0.670   0.542   0.610   0.552   0.391   0.464   0.401
260   Y        -0.353  -0.344  -0.292  -0.368  -0.348  -0.269  -0.556  -0.543  -0.469
261   K         0.649   0.612   0.647   0.478   0.403   0.448   0.391   0.318   0.357
262   K        -0.353  -0.344  -0.292  -0.682  -0.681  -0.587  -0.556  -0.543  -0.469
263   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   L         0.649   0.603   0.647   0.352   0.263   0.318   0.391   0.301   0.357
270   L         0.810   0.753   0.746   0.711   0.631   0.618   0.688   0.583   0.546
271   Q        -0.225  -0.254  -0.241  -0.238  -0.304  -0.296  -0.379  -0.419  -0.398
272   S         0.810   0.753   0.746   0.690   0.597   0.576   0.688   0.583   0.546
273   I        -0.225  -0.181  -0.213  -0.461  -0.389  -0.450  -0.379  -0.315  -0.359
274   D        -0.225  -0.181  -0.213  -0.323  -0.253  -0.308  -0.379  -0.315  -0.359
275   F        -0.225  -0.181  -0.213  -0.153  -0.092  -0.116  -0.379  -0.315  -0.359
276   T        -0.353  -0.347  -0.292  -0.243  -0.245  -0.143  -0.556  -0.548  -0.469
277   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   S         0.649   0.624   0.647   0.543   0.508   0.550   0.391   0.340   0.357
279   K        -0.225  -0.218  -0.218  -0.229  -0.225  -0.217  -0.379  -0.368  -0.366
280   K        -0.976  -0.969  -0.921  -0.862  -0.843  -0.769  -0.912  -0.901  -0.830
281   S        -0.031   0.036  -0.098   0.128   0.235   0.029  -0.101  -0.004  -0.194
282   D        -0.859  -0.882  -0.858  -0.934  -0.964  -0.927  -0.784  -0.807  -0.762
283   S        -0.859  -0.842  -0.846  -0.839  -0.810  -0.833  -0.784  -0.762  -0.748
284   E        -1.460  -1.456  -1.409  -1.531  -1.533  -1.447  -1.125  -1.117  -1.046
285   T        -1.460  -1.456  -1.409  -1.408  -1.409  -1.322  -1.125  -1.117  -1.046
286   G         0.944   0.952   0.845   1.119   1.131   0.959   0.922   0.934   0.730
287   G        -0.031  -0.083  -0.132   0.078  -0.011  -0.114  -0.101  -0.175  -0.244
288   D        -0.031  -0.083  -0.132  -0.043  -0.120  -0.188  -0.101  -0.175  -0.244
289   I         0.570   0.567   0.611   0.258   0.246   0.303   0.240   0.231   0.286
290   L        -0.859  -0.891  -0.876  -1.036  -1.086  -1.064  -0.784  -0.817  -0.781
291   L         0.570   0.557   0.609   0.220   0.194   0.272   0.240   0.211   0.282
292   K         0.944   0.929   0.845   1.007   0.986   0.876   0.922   0.895   0.730
293   K        -0.859  -0.863  -0.854  -0.629  -0.627  -0.617  -0.784  -0.787  -0.758
294   E         0.944   0.952   0.845   1.055   1.068   0.918   0.922   0.934   0.730
295   G         0.570   0.570   0.612   0.480   0.475   0.530   0.240   0.236   0.288
296   E        -0.258  -0.277  -0.235  -0.420  -0.450  -0.386  -0.442  -0.462  -0.398
297   V        -0.859  -0.852  -0.853  -0.981  -0.972  -0.982  -0.784  -0.774  -0.757
298   Y        -0.031  -0.083  -0.132   0.220   0.132   0.031  -0.101  -0.175  -0.244
299   Y        -0.859  -0.828  -0.850  -0.490  -0.449  -0.464  -0.784  -0.745  -0.753
300   V         0.944   0.901   0.837   0.863   0.798   0.694   0.922   0.846   0.716
301   A        -0.031  -0.083  -0.132   0.049  -0.037  -0.130  -0.101  -0.175  -0.244
302   S         2.029   2.040   2.111   1.938   1.955   2.064   2.287   2.303   2.421
303   S        -0.976  -0.970  -0.921  -1.014  -0.982  -0.923  -0.912  -0.902  -0.830
304   R        -0.353  -0.346  -0.292  -0.627  -0.622  -0.531  -0.556  -0.546  -0.469
305   D        -0.258  -0.277  -0.235  -0.427  -0.445  -0.369  -0.442  -0.462  -0.398
306   E        -0.258  -0.250  -0.239  -0.364  -0.357  -0.310  -0.442  -0.430  -0.402
307   K        -0.859  -0.858  -0.841  -1.038  -1.038  -1.021  -0.784  -0.779  -0.743
308   F        -0.031  -0.083  -0.132   0.340   0.270   0.206  -0.101  -0.175  -0.244
309   H        -0.859  -0.891  -0.876  -0.700  -0.766  -0.762  -0.784  -0.817  -0.781
310   A        -1.460  -1.456  -1.409  -1.455  -1.448  -1.370  -1.125  -1.117  -1.046
311   V         2.029   2.040   2.111   1.923   1.938   2.049   2.287   2.303   2.421
312   E        -0.859  -0.858  -0.841  -0.729  -0.727  -0.691  -0.784  -0.779  -0.743
313   S        -0.859  -0.828  -0.850  -0.798  -0.740  -0.796  -0.784  -0.745  -0.753
314   I         0.570   0.562   0.609   0.258   0.235   0.298   0.240   0.222   0.282
315   E        -1.460  -1.456  -1.409  -1.369  -1.370  -1.283  -1.125  -1.117  -1.046
316   N        -0.859  -0.815  -0.852  -0.812  -0.733  -0.819  -0.784  -0.731  -0.755
317   G        -0.859  -0.852  -0.853  -0.703  -0.701  -0.697  -0.784  -0.774  -0.757
318   S        -1.460  -1.456  -1.409  -1.517  -1.510  -1.433  -1.125  -1.117  -1.046
319   N         2.029   2.040   2.111   2.046   2.060   2.174   2.287   2.303   2.421
320   G         2.029   2.040   2.111   2.181   2.198   2.311   2.287   2.303   2.421
321   V        -0.031  -0.083  -0.132  -0.006  -0.075  -0.135  -0.101  -0.175  -0.244
322   I         2.029   2.040   2.111   2.007   2.021   2.134   2.287   2.303   2.421
323   L        -0.031  -0.083  -0.132   0.051  -0.013  -0.056  -0.101  -0.175  -0.244
324   M        -0.031   0.020  -0.098  -0.037   0.032  -0.126  -0.101  -0.027  -0.195
325   V        -0.031   0.002  -0.095   0.016   0.071  -0.077  -0.101  -0.055  -0.190
326   D         0.944   0.901   0.837   0.883   0.818   0.719   0.922   0.846   0.716
327   F        -1.460  -1.456  -1.409  -1.374  -1.380  -1.288  -1.125  -1.117  -1.046
328   T        -0.258  -0.277  -0.235  -0.414  -0.452  -0.391  -0.442  -0.462  -0.398
329   L         2.029   2.040   2.111   1.908   1.925   2.034   2.287   2.303   2.421
330   V        -0.031  -0.010  -0.095  -0.162  -0.128  -0.276  -0.101  -0.070  -0.191
331   G        -0.859  -0.815  -0.852  -0.713  -0.653  -0.683  -0.784  -0.731  -0.755
332   P         2.029   2.040   2.111   2.210   2.228   2.340   2.287   2.303   2.421
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12331
Output conservation file - output/Q12331
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
