1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    M         1.217   1.277   1.327   1.319   1.409   1.483   1.286   1.366   1.438
22    V        -1.222  -1.162  -1.091  -1.301  -1.189  -1.124  -1.214  -1.111  -0.988
23    Y        -0.715  -0.705  -0.588  -0.851  -0.868  -0.711  -0.915  -0.873  -0.712
24    T        -1.327  -1.259  -1.119  -1.223  -1.165  -0.940  -1.308  -1.196  -1.013
25    G         1.217   1.277   1.327   0.865   0.962   1.079   1.286   1.366   1.438
26    F        -0.987  -1.100  -1.081  -0.726  -0.916  -0.825  -0.920  -1.035  -0.975
27    G        -0.304  -0.566  -0.549  -0.545  -0.915  -0.844  -0.331  -0.676  -0.658
28    L        -1.222  -1.281  -1.109  -1.193  -1.217  -0.964  -1.214  -1.212  -1.004
29    E        -1.743  -1.668  -1.514  -1.730  -1.630  -1.402  -1.508  -1.377  -1.179
30    Q        -2.121  -1.975  -1.836  -1.901  -1.683  -1.493  -1.655  -1.474  -1.289
31    I        -1.222  -0.894  -1.044  -1.334  -0.803  -1.059  -1.214  -0.809  -0.939
32    S        -0.701  -0.731  -0.580  -0.972  -1.026  -0.788  -0.920  -0.898  -0.702
33    P        -1.156  -1.211  -1.106  -1.149  -1.296  -1.119  -1.116  -1.145  -1.001
34    A        -0.987  -0.933  -1.046  -0.839  -0.732  -0.969  -0.920  -0.858  -0.938
35    Q        -0.987  -0.922  -1.049  -0.811  -0.753  -0.924  -0.920  -0.847  -0.941
36    K        -1.600  -1.569  -1.496  -1.415  -1.386  -1.250  -1.361  -1.296  -1.164
37    K        -0.304  -0.566  -0.549  -0.139  -0.508  -0.518  -0.331  -0.676  -0.658
38    P        -1.222  -1.163  -1.083  -1.350  -1.289  -1.125  -1.214  -1.112  -0.980
39    Y        -1.743  -1.679  -1.506  -1.621  -1.450  -1.249  -1.508  -1.383  -1.173
40    N        -1.743  -1.462  -1.479  -2.078  -1.715  -1.568  -1.508  -1.212  -1.152
41    E        -1.222  -1.275  -1.100  -1.119  -1.120  -0.896  -1.214  -1.206  -0.996
42    L        -0.608  -0.549  -0.550  -0.667  -0.536  -0.551  -0.772  -0.653  -0.662
43    T        -0.608  -0.516  -0.541  -0.557  -0.341  -0.450  -0.772  -0.606  -0.649
44    P        -0.304  -0.258  -0.501  -0.103  -0.024  -0.404  -0.331  -0.272  -0.595
45    E        -0.304  -0.023  -0.454  -0.096   0.302  -0.307  -0.331   0.048  -0.531
46    E         1.217   1.277   1.327   1.310   1.401   1.475   1.286   1.366   1.438
47    Q         0.074  -0.005   0.101   0.089  -0.074   0.062  -0.184  -0.348  -0.199
48    G        -0.701  -0.659  -0.573  -1.358  -1.192  -1.020  -0.920  -0.811  -0.694
49    E         0.434   0.236   0.214   0.531   0.207   0.115   0.404   0.077   0.006
50    R        -1.222  -1.119  -1.084  -1.143  -0.999  -0.933  -1.214  -1.062  -0.979
51    G        -0.304  -0.566  -0.549  -0.517  -0.847  -0.786  -0.331  -0.676  -0.658
52    A        -0.304  -0.566  -0.549  -0.429  -0.765  -0.721  -0.331  -0.676  -0.658
53    E        -1.600  -1.439  -1.477  -1.462  -1.303  -1.295  -1.361  -1.178  -1.148
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    M        -0.608  -0.513  -0.569  -0.609  -0.482  -0.541  -0.772  -0.665  -0.690
69    I        -0.608  -0.488  -0.563  -0.584  -0.427  -0.506  -0.772  -0.637  -0.684
70    M        -1.222  -1.147  -1.086  -1.129  -0.992  -0.903  -1.214  -1.099  -0.983
71    N        -1.222  -1.067  -1.065  -1.513  -1.270  -1.174  -1.214  -0.998  -0.960
72    F        -0.987  -1.110  -1.080  -0.890  -1.099  -1.098  -0.920  -1.045  -0.974
73    M         1.217   1.277   1.327   1.319   1.409   1.483   1.286   1.366   1.438
74    T        -1.743  -1.552  -1.490  -1.528  -1.210  -1.160  -1.508  -1.277  -1.160
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    S         1.217   1.277   1.327   1.207   1.285   1.383   1.286   1.366   1.438
80    C         1.217   1.277   1.327   1.507   1.584   1.650   1.286   1.366   1.438
81    P        -0.304  -0.566  -0.549  -0.114  -0.485  -0.505  -0.331  -0.676  -0.658
82    G        -0.304  -0.566  -0.549  -0.605  -1.002  -0.975  -0.331  -0.676  -0.658
83    K         1.217   1.277   1.327   1.289   1.384   1.456   1.286   1.366   1.438
84    S        -0.701  -0.516  -0.568  -0.879  -0.588  -0.674  -0.920  -0.686  -0.690
85    V        -0.304  -0.342  -0.509  -0.175  -0.248  -0.584  -0.331  -0.407  -0.605
86    V        -0.608  -0.299  -0.517  -0.584  -0.094  -0.427  -0.772  -0.337  -0.618
87    S        -0.087  -0.018   0.100  -0.571  -0.473  -0.256  -0.478  -0.372  -0.202
88    G         1.217   1.277   1.327   0.902   0.992   1.112   1.286   1.366   1.438
89    V        -0.304  -0.236  -0.496  -0.233  -0.137  -0.670  -0.331  -0.246  -0.588
90    T        -1.222  -1.281  -1.109  -1.280  -1.401  -1.162  -1.214  -1.212  -1.004
91    G         1.217   1.277   1.327   0.902   0.992   1.112   1.286   1.366   1.438
92    F         1.217   1.277   1.327   1.297   1.388   1.464   1.286   1.366   1.438
93    A        -0.304  -0.381  -0.513  -0.533  -0.714  -0.879  -0.331  -0.451  -0.610
94    L         1.217   1.277   1.327   1.250   1.323   1.422   1.286   1.366   1.438
95    G         1.217   1.277   1.327   0.902   0.992   1.112   1.286   1.366   1.438
96    G         1.217   1.277   1.327   0.902   0.992   1.112   1.286   1.366   1.438
97    V        -0.608  -0.640  -0.564  -0.587  -0.585  -0.509  -0.772  -0.773  -0.680
98    L         0.074   0.290   0.190  -0.010   0.358   0.160  -0.184   0.169  -0.037
99    G         1.217   1.277   1.327   0.902   0.992   1.112   1.286   1.366   1.438
100   L         0.074  -0.005   0.101  -0.028  -0.189  -0.011  -0.184  -0.348  -0.199
101   F         1.217   1.277   1.327   1.297   1.388   1.464   1.286   1.366   1.438
102   M         0.497   0.222   0.194   0.681   0.327   0.233   0.498   0.055  -0.029
103   A         0.497   0.222   0.194   0.311  -0.185  -0.119   0.498   0.055  -0.029
104   S         1.217   1.277   1.327   1.207   1.270   1.384   1.286   1.366   1.438
105   M         0.497   0.222   0.194   0.666   0.325   0.188   0.498   0.055  -0.029
106   A         0.434   0.572   0.186   0.208   0.279  -0.144   0.404   0.603  -0.045
107   Y         1.217   1.277   1.327   1.394   1.465   1.550   1.286   1.366   1.438
108   D         1.217   1.277   1.327   1.368   1.402   1.527   1.286   1.366   1.438
109   T        -0.304  -0.160  -0.513  -0.100   0.100  -0.514  -0.331  -0.130  -0.610
110   P         1.217   1.277   1.327   1.319   1.430   1.483   1.286   1.366   1.438
111   L        -1.222  -1.227  -1.109  -1.155  -1.116  -0.947  -1.214  -1.165  -1.004
112   H        -0.087   0.026   0.113  -0.295  -0.035   0.029  -0.478  -0.292  -0.178
113   T        -0.304  -0.461  -0.549  -0.053  -0.317  -0.488  -0.331  -0.548  -0.658
114   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   G         0.261   0.142   0.172  -0.080  -0.229  -0.149   0.133  -0.084  -0.069
133   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   R        -2.121  -1.965  -1.835  -1.784  -1.479  -1.384  -1.655  -1.468  -1.288
136   T        -1.637  -1.566  -1.485  -1.887  -1.792  -1.570  -1.416  -1.306  -1.157
137   V        -0.188  -0.531  -0.551   0.076  -0.365  -0.468  -0.178  -0.634  -0.661
138   Q        -1.637  -1.613  -1.498  -1.487  -1.364  -1.282  -1.416  -1.335  -1.167
139   Q        -2.424  -2.214  -2.114  -1.914  -1.650  -1.470  -1.753  -1.535  -1.370
140   I        -0.769  -0.604  -0.590  -0.836  -0.604  -0.574  -0.965  -0.729  -0.712
141   S        -1.100  -1.037  -1.074  -1.204  -1.118  -1.089  -1.078  -0.980  -0.969
142   D        -0.502  -0.633  -0.577  -0.402  -0.598  -0.562  -0.628  -0.786  -0.701
143   L        -0.188  -0.531  -0.551  -0.021  -0.494  -0.567  -0.178  -0.634  -0.661
144   P         1.217   1.277   1.327   1.325   1.449   1.489   1.286   1.366   1.438
145   F        -0.047   0.059   0.106  -0.240   0.003  -0.006  -0.403  -0.231  -0.191
146   R        -0.047  -0.008   0.100  -0.135  -0.091   0.110  -0.403  -0.353  -0.201
147   Q         0.143   0.003   0.101   0.223   0.039   0.083  -0.065  -0.334  -0.200
148   Q         1.217   1.277   1.327   1.387   1.504   1.544   1.286   1.366   1.438
149   M        -1.100  -1.078  -1.080  -0.989  -0.967  -0.946  -1.078  -1.040  -0.978
150   K         0.497   0.222   0.194   0.669   0.289   0.254   0.498   0.055  -0.029
151   L        -0.644  -0.649  -0.572  -0.675  -0.666  -0.468  -0.853  -0.811  -0.695
152   Q         0.497   0.420   0.206   0.687   0.622   0.130   0.498   0.376  -0.009
153   F         0.497   0.222   0.194   0.607   0.181   0.055   0.498   0.055  -0.029
154   T        -1.637  -1.613  -1.495  -1.543  -1.481  -1.349  -1.416  -1.335  -1.164
155   D         1.217   1.277   1.327   1.379   1.420   1.537   1.286   1.366   1.438
156   M         1.217   1.277   1.327   1.317   1.459   1.482   1.286   1.366   1.438
157   G         0.497   0.693   0.231   0.207   0.549  -0.208   0.498   0.771   0.035
158   K        -0.188  -0.531  -0.551   0.008  -0.509  -0.549  -0.178  -0.634  -0.661
159   K         0.497   0.677   0.232   0.823   1.015   0.396   0.498   0.749   0.038
160   S        -0.502  -0.202  -0.497  -0.658  -0.221  -0.625  -0.628  -0.212  -0.593
161   Y        -0.188  -0.346  -0.498   0.164  -0.101  -0.268  -0.178  -0.417  -0.590
162   S         1.217   1.277   1.327   1.207   1.270   1.384   1.286   1.366   1.438
163   S         0.143   0.003   0.101   0.080  -0.166   0.020  -0.065  -0.334  -0.200
164   A         1.217   1.277   1.327   0.971   0.967   1.174   1.286   1.366   1.438
165   K         1.217   1.277   1.327   1.290   1.370   1.457   1.286   1.366   1.438
166   N         1.217   1.277   1.327   1.452   1.522   1.601   1.286   1.366   1.438
167   F         1.217   1.277   1.327   1.298   1.435   1.464   1.286   1.366   1.438
168   G         0.497   0.420   0.206   0.207   0.162  -0.258   0.498   0.376  -0.009
169   Y        -0.833  -1.044  -1.065  -0.515  -0.879  -0.916  -0.740  -0.980  -0.958
170   I        -0.188  -0.531  -0.551   0.086  -0.486  -0.491  -0.178  -0.634  -0.661
171   G         1.217   1.277   1.327   0.904   1.069   1.114   1.286   1.366   1.438
172   M        -0.833  -1.044  -1.065  -0.731  -1.071  -1.256  -0.740  -0.980  -0.958
173   I        -0.644  -0.588  -0.559  -0.668  -0.565  -0.505  -0.853  -0.718  -0.675
174   Y         0.143   0.174   0.144   0.226   0.266   0.170  -0.065  -0.028  -0.120
175   A         0.143   0.361   0.173  -0.064   0.269  -0.071  -0.065   0.283  -0.068
176   G         1.217   1.277   1.327   0.904   1.069   1.114   1.286   1.366   1.438
177   V        -0.833  -1.044  -1.065  -0.544  -0.886  -0.900  -0.740  -0.980  -0.958
178   E         1.217   1.277   1.327   1.325   1.519   1.489   1.286   1.366   1.438
179   C         1.217   1.277   1.327   1.501   1.570   1.645   1.286   1.366   1.438
180   V        -1.762  -1.570  -1.497  -1.866  -1.487  -1.437  -1.528  -1.292  -1.167
181   I         0.143   0.382   0.171   0.210   0.514   0.218  -0.065   0.317  -0.071
182   E         1.217   1.277   1.327   1.325   1.519   1.489   1.286   1.366   1.438
183   S        -0.188  -0.531  -0.551  -0.194  -0.851  -0.924  -0.178  -0.634  -0.661
184   L         0.497   0.222   0.194   0.613   0.252   0.156   0.498   0.055  -0.029
185   R         1.217   1.277   1.327   1.471   1.510   1.618   1.286   1.366   1.438
186   A         1.217   1.277   1.327   0.971   0.967   1.174   1.286   1.366   1.438
187   K         1.217   1.277   1.327   1.290   1.370   1.457   1.286   1.366   1.438
188   N        -0.502  -0.569  -0.564  -0.206  -0.304  -0.292  -0.628  -0.681  -0.680
189   D         1.217   1.277   1.327   1.379   1.420   1.537   1.286   1.366   1.438
190   I         0.497   0.420   0.206   0.716   0.540   0.250   0.498   0.376  -0.009
191   Y        -0.188  -0.170  -0.485   0.103   0.093  -0.378  -0.178  -0.154  -0.573
192   N         1.217   1.277   1.327   1.452   1.522   1.601   1.286   1.366   1.438
193   G         0.497   0.222   0.194   0.207  -0.187  -0.282   0.498   0.055  -0.029
194   V         0.143   0.071   0.107   0.192   0.071   0.091  -0.065  -0.209  -0.187
195   T        -0.769  -0.461  -0.567  -1.158  -0.764  -0.792  -0.965  -0.531  -0.682
196   A         1.217   1.277   1.327   0.971   0.967   1.174   1.286   1.366   1.438
197   G         1.217   1.277   1.327   0.904   1.069   1.114   1.286   1.366   1.438
198   F        -0.188  -0.322  -0.530   0.223   0.015  -0.339  -0.178  -0.390  -0.633
199   F        -0.850  -0.766  -0.618  -1.018  -0.876  -0.643  -1.078  -0.942  -0.748
200   T         1.217   1.277   1.327   1.414   1.493   1.568   1.286   1.366   1.438
201   G         1.217   1.277   1.327   0.904   1.069   1.114   1.286   1.366   1.438
202   A        -0.047   0.051   0.101  -0.758  -0.555  -0.478  -0.403  -0.246  -0.198
203   G        -0.188  -0.531  -0.551  -0.425  -0.964  -0.951  -0.178  -0.634  -0.661
204   L         1.217   1.277   1.327   1.259   1.356   1.429   1.286   1.366   1.438
205   A         1.217   1.277   1.327   0.971   0.967   1.174   1.286   1.366   1.438
206   Y        -1.306  -1.233  -1.106  -1.239  -1.114  -0.932  -1.303  -1.168  -1.002
207   K        -0.502  -0.633  -0.577  -0.384  -0.572  -0.442  -0.628  -0.786  -0.700
208   A        -0.644  -0.652  -0.569  -1.160  -1.192  -0.990  -0.853  -0.815  -0.691
209   G         1.217   1.277   1.327   0.904   1.069   1.114   1.286   1.366   1.438
210   P         1.217   1.277   1.327   1.325   1.449   1.489   1.286   1.366   1.438
211   Q         0.497   0.222   0.194   0.740   0.373   0.257   0.498   0.055  -0.029
212   A         1.217   1.277   1.327   0.971   0.967   1.174   1.286   1.366   1.438
213   A         0.497   0.222   0.194   0.335  -0.151  -0.047   0.498   0.055  -0.029
214   L        -0.188  -0.531  -0.551  -0.069  -0.581  -0.689  -0.178  -0.634  -0.661
215   M        -0.188  -0.322  -0.530   0.055  -0.110  -0.482  -0.178  -0.390  -0.633
216   G         1.217   1.277   1.327   0.904   1.069   1.114   1.286   1.366   1.438
217   G         0.143   0.067   0.107   0.206   0.008  -0.059  -0.065  -0.218  -0.189
218   A         1.217   1.277   1.327   0.971   0.967   1.174   1.286   1.366   1.438
219   G         1.217   1.277   1.327   0.904   1.069   1.114   1.286   1.366   1.438
220   F         1.217   1.277   1.327   1.298   1.435   1.464   1.286   1.366   1.438
221   A         0.497   0.222   0.194   0.266  -0.256  -0.253   0.498   0.055  -0.029
222   A         0.497   0.222   0.194   0.319  -0.154  -0.096   0.498   0.055  -0.029
223   F         1.217   1.277   1.327   1.298   1.435   1.464   1.286   1.366   1.438
224   S         1.217   1.277   1.327   1.207   1.270   1.384   1.286   1.366   1.438
225   A        -1.100  -1.037  -1.080  -1.265  -1.229  -1.120  -1.078  -0.979  -0.976
226   A         0.497   0.222   0.194   0.266  -0.256  -0.253   0.498   0.055  -0.029
227   I         1.217   1.277   1.327   1.368   1.365   1.527   1.286   1.366   1.438
228   D         0.497   0.222   0.194   0.737   0.340   0.265   0.498   0.055  -0.029
229   L        -1.637  -1.638  -1.491  -1.649  -1.656  -1.429  -1.416  -1.352  -1.161
230   Y         0.497   0.420   0.206   0.794   0.694   0.406   0.498   0.376  -0.009
231   M         0.143   0.370   0.167   0.135   0.560   0.134  -0.065   0.298  -0.079
232   K        -1.100  -1.049  -1.076  -0.796  -0.719  -0.725  -1.078  -0.993  -0.971
233   S        -0.304  -0.368  -0.560  -0.181  -0.308  -0.537  -0.331  -0.440  -0.673
234   E        -0.107  -0.019   0.100  -0.256  -0.089   0.083  -0.515  -0.374  -0.202
235   D        -1.323  -1.179  -1.117  -1.371  -1.225  -1.101  -1.316  -1.121  -1.011
236   G        -0.881  -0.774  -0.618  -1.547  -1.330  -1.057  -1.116  -0.951  -0.747
237   R        -1.764  -1.645  -1.517  -1.735  -1.613  -1.423  -1.516  -1.347  -1.181
238   P         1.217   1.277   1.327   1.319   1.430   1.483   1.286   1.366   1.438
239   P         0.434   0.225   0.166   0.578   0.280   0.119   0.404   0.059  -0.081
240   Q        -1.222  -1.115  -1.092  -1.230  -0.954  -1.008  -1.214  -1.065  -0.989
241   N        -0.987  -1.005  -1.079  -0.629  -0.667  -0.808  -0.920  -0.935  -0.973
242   D         1.217   1.277   1.327   1.368   1.402   1.527   1.286   1.366   1.438
243   F        -1.222  -1.218  -1.109  -1.093  -0.963  -0.857  -1.214  -1.161  -1.004
244   K        -0.608  -0.693  -0.588  -0.667  -0.915  -0.730  -0.772  -0.849  -0.711
245   E        -0.987  -0.685  -1.031  -0.756  -0.263  -0.845  -0.920  -0.541  -0.923
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12328
Output conservation file - output/Q12328
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
