1     M         2.005   2.036   2.118   2.304   2.352   2.489   2.269   2.315   2.463
2     T         0.025   0.079   0.092   0.023   0.116   0.121  -0.249  -0.169  -0.165
3     T        -0.635  -0.605  -0.538  -0.483  -0.430  -0.336  -0.752  -0.712  -0.628
4     L        -0.635  -0.605  -0.538  -0.737  -0.710  -0.592  -0.752  -0.712  -0.628
5     M        -0.635  -0.605  -0.538  -0.564  -0.506  -0.417  -0.752  -0.712  -0.628
6     G        -0.635  -0.605  -0.538  -0.582  -0.543  -0.435  -0.752  -0.712  -0.628
7     K        -0.635  -0.605  -0.538  -0.974  -0.953  -0.833  -0.752  -0.712  -0.628
8     F         0.685   0.710   0.792   0.645   0.694   0.817   0.255   0.290   0.406
9     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    L         0.934   0.869   0.906   0.861   0.742   0.798   0.759   0.618   0.648
39    H         0.025  -0.017   0.045  -0.032  -0.151  -0.047  -0.249  -0.314  -0.237
40    C        -0.635  -0.605  -0.538  -0.650  -0.595  -0.505  -0.752  -0.712  -0.628
41    K         0.934   1.015   0.949   0.513   0.630   0.524   0.759   0.901   0.735
42    K        -0.635  -0.605  -0.538  -0.886  -0.868  -0.744  -0.752  -0.712  -0.628
43    Q        -0.635  -0.605  -0.538  -0.850  -0.815  -0.707  -0.752  -0.712  -0.628
44    Q         0.025   0.068   0.088  -0.218  -0.130  -0.149  -0.249  -0.185  -0.172
45    F         0.685   0.710   0.792   0.435   0.465   0.595   0.255   0.290   0.406
46    V         0.025  -0.017   0.045   0.125   0.041   0.124  -0.249  -0.314  -0.237
47    E         0.025  -0.017   0.045   0.103   0.047   0.119  -0.249  -0.314  -0.237
48    E        -0.635  -0.605  -0.538  -0.592  -0.533  -0.446  -0.752  -0.712  -0.628
49    A        -0.635  -0.605  -0.538  -0.729  -0.670  -0.584  -0.752  -0.712  -0.628
50    V         0.025  -0.017   0.045  -0.099  -0.181  -0.077  -0.249  -0.314  -0.237
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    R         0.934   0.869   0.906   0.793   0.642   0.668   0.759   0.618   0.648
66    L        -0.804  -0.751  -0.834  -0.308  -0.190  -0.358  -0.690  -0.632  -0.703
67    I        -0.192  -0.019  -0.281  -0.018   0.235  -0.132  -0.197   0.035  -0.309
68    S        -0.804  -0.881  -0.864  -0.803  -0.930  -0.900  -0.690  -0.769  -0.734
69    N        -0.192  -0.129  -0.303   0.010   0.097  -0.161  -0.197  -0.114  -0.337
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    K        -0.004   0.007   0.061  -0.368  -0.331  -0.242  -0.309  -0.291  -0.219
72    K        -0.192  -0.088  -0.295  -0.358  -0.229  -0.489  -0.197  -0.057  -0.327
73    I        -1.700  -1.669  -1.610  -1.584  -1.532  -1.450  -1.184  -1.148  -1.069
74    G        -1.323  -1.270  -1.261  -0.991  -0.919  -0.889  -1.019  -0.961  -0.928
75    K        -1.323  -1.335  -1.293  -1.188  -1.161  -1.168  -1.019  -1.020  -0.954
76    K        -0.427  -0.459  -0.448  -0.699  -0.745  -0.758  -0.526  -0.564  -0.532
77    -        -1.060  -1.031  -0.965  -0.988  -0.934  -0.847  -0.954  -0.917  -0.834
78    S        -0.804  -0.819  -0.843  -0.644  -0.696  -0.733  -0.690  -0.707  -0.712
79    D        -1.323  -1.335  -1.293  -1.144  -1.182  -1.100  -1.019  -1.020  -0.954
80    F        -0.427  -0.512  -0.455  -0.460  -0.596  -0.534  -0.526  -0.610  -0.537
81    V        -1.323  -1.304  -1.280  -1.077  -1.031  -1.030  -1.019  -0.995  -0.944
82    Q        -1.323  -1.335  -1.293  -1.423  -1.423  -1.323  -1.019  -1.020  -0.954
83    A        -0.804  -0.846  -0.852  -0.439  -0.489  -0.514  -0.690  -0.734  -0.721
84    R        -0.427  -0.499  -0.449  -0.718  -0.800  -0.743  -0.526  -0.592  -0.528
85    N        -0.946  -0.850  -0.889  -1.047  -0.961  -0.951  -0.855  -0.759  -0.766
86    W         2.005   2.036   2.118   2.284   2.338   2.468   2.269   2.315   2.463
87    V        -0.946  -0.931  -0.906  -0.920  -0.948  -0.863  -0.855  -0.833  -0.781
88    G        -0.804  -0.868  -0.876  -0.710  -0.831  -0.858  -0.690  -0.756  -0.746
89    A        -0.946  -0.887  -0.892  -0.847  -0.766  -0.753  -0.855  -0.791  -0.769
90    L         0.079   0.032   0.082   0.021  -0.020   0.021  -0.193  -0.250  -0.189
91    N        -0.967  -0.918  -0.908  -1.206  -1.135  -1.130  -0.864  -0.805  -0.779
92    V        -0.527  -0.478  -0.479  -0.428  -0.355  -0.347  -0.640  -0.581  -0.565
93    T         0.079   0.091   0.091  -0.098  -0.114  -0.102  -0.193  -0.187  -0.179
94    G        -0.361  -0.309  -0.418  -0.170  -0.109  -0.263  -0.416  -0.345  -0.484
95    L         0.079   0.114   0.100   0.036   0.096   0.062  -0.193  -0.155  -0.166
96    P         2.005   2.036   2.118   2.180   2.241   2.363   2.269   2.315   2.463
97    L        -1.323  -1.335  -1.283  -1.354  -1.442  -1.311  -1.019  -1.020  -0.947
98    N        -1.323  -1.343  -1.274  -1.190  -1.236  -1.129  -1.019  -1.026  -0.939
99    Q        -0.569  -0.572  -0.495  -0.606  -0.597  -0.482  -0.690  -0.680  -0.586
100   F         0.489   0.376   0.289   0.757   0.649   0.489   0.461   0.286   0.143
101   I        -1.700  -1.669  -1.610  -1.442  -1.395  -1.307  -1.184  -1.148  -1.069
102   L        -0.804  -0.760  -0.844  -0.528  -0.435  -0.579  -0.690  -0.636  -0.713
103   R         0.093   0.143   0.116  -0.194  -0.135  -0.140  -0.197  -0.136  -0.151
104   Y         0.866   0.796   0.845   0.995   0.896   0.921   0.625   0.469   0.520
105   D         0.705   0.722   0.799   0.441   0.446   0.572   0.296   0.316   0.422
106   R         1.224   1.187   1.096   1.184   1.132   0.967   1.283   1.212   1.025
107   A         1.224   1.322   1.119   1.212   1.327   1.093   1.283   1.441   1.070
108   S         1.224   1.299   1.115   1.172   1.265   1.021   1.283   1.403   1.061
109   G         2.005   2.036   2.118   2.149   2.199   2.332   2.269   2.315   2.463
110   P         1.224   1.299   1.115   1.411   1.524   1.230   1.283   1.403   1.061
111   G         2.005   2.036   2.118   2.149   2.199   2.332   2.269   2.315   2.463
112   G         2.005   2.036   2.118   2.149   2.199   2.332   2.269   2.315   2.463
113   Q         2.005   2.036   2.118   2.098   2.127   2.280   2.269   2.315   2.463
114   N         0.185   0.206   0.176   0.088   0.169   0.100  -0.033   0.015  -0.043
115   V         2.005   2.036   2.118   2.102   2.162   2.284   2.269   2.315   2.463
116   N         2.005   2.036   2.118   2.085   2.139   2.267   2.269   2.315   2.463
117   K         2.005   2.036   2.118   1.666   1.694   1.843   2.269   2.315   2.463
118   V         0.093   0.032   0.105   0.021  -0.055   0.048  -0.197  -0.261  -0.165
119   N         0.705   0.748   0.810   0.430   0.512   0.592   0.296   0.371   0.446
120   S         0.705   0.708   0.790   0.383   0.381   0.520   0.296   0.286   0.403
121   K         2.005   2.036   2.118   1.666   1.694   1.843   2.269   2.315   2.463
122   C         0.093   0.032   0.105   0.247   0.187   0.283  -0.197  -0.261  -0.165
123   T         1.224   1.111   1.089   1.367   1.216   1.187   1.283   1.078   1.011
124   L         0.185   0.223   0.150   0.129   0.175   0.077  -0.033   0.001  -0.094
125   T        -0.804  -0.833  -0.866  -0.722  -0.805  -0.867  -0.690  -0.720  -0.736
126   L         0.489   0.443   0.296   0.638   0.593   0.391   0.461   0.390   0.153
127   S        -1.323  -1.230  -1.256  -0.993  -0.838  -0.895  -1.019  -0.925  -0.924
128   -         0.025  -0.024   0.045   0.100   0.044   0.118  -0.249  -0.325  -0.237
129   -         0.025   0.144   0.088  -0.331  -0.199  -0.228  -0.249  -0.068  -0.172
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   G        -0.946  -0.979  -0.913  -0.752  -0.802  -0.694  -0.855  -0.874  -0.788
134   L        -0.427  -0.353  -0.410  -0.375  -0.253  -0.336  -0.526  -0.424  -0.481
135   S        -0.427  -0.450  -0.442  -0.584  -0.634  -0.596  -0.526  -0.551  -0.525
136   N        -1.323  -1.206  -1.261  -1.431  -1.235  -1.346  -1.019  -0.901  -0.928
137   C         1.224   1.187   1.096   1.538   1.504   1.348   1.283   1.212   1.025
138   A        -0.967  -0.972  -0.941  -0.869  -0.872  -0.848  -0.864  -0.861  -0.811
139   W         2.005   2.036   2.118   2.276   2.321   2.460   2.269   2.315   2.463
140   I         0.866   0.908   0.895   0.839   0.933   0.869   0.625   0.695   0.625
141   P         2.005   2.036   2.118   2.179   2.231   2.362   2.269   2.315   2.463
142   Q        -0.804  -0.804  -0.833  -0.653  -0.643  -0.725  -0.690  -0.688  -0.701
143   E        -0.427  -0.499  -0.449  -0.291  -0.359  -0.296  -0.526  -0.592  -0.528
144   V         0.093   0.035   0.107   0.018  -0.040   0.052  -0.197  -0.256  -0.160
145   R        -0.192  -0.288  -0.344  -0.185  -0.350  -0.455  -0.197  -0.323  -0.390
146   N        -1.323  -1.270  -1.260  -1.234  -1.130  -1.152  -1.019  -0.961  -0.927
147   I        -0.192  -0.234  -0.336   0.082   0.020  -0.125  -0.197  -0.255  -0.380
148   L         0.185   0.102   0.143   0.123   0.029   0.063  -0.033  -0.142  -0.102
149   S        -1.323  -1.259  -1.258  -1.459  -1.369  -1.347  -1.019  -0.952  -0.925
150   S        -0.946  -0.926  -0.896  -1.239  -1.246  -1.148  -0.855  -0.827  -0.773
151   G        -0.427  -0.424  -0.429  -0.461  -0.411  -0.455  -0.526  -0.513  -0.508
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   R        -1.323  -1.327  -1.275  -1.093  -1.039  -1.033  -1.019  -1.013  -0.940
175   F        -0.427  -0.470  -0.429  -0.412  -0.438  -0.427  -0.526  -0.560  -0.504
176   R         0.489   0.443   0.296   0.551   0.498   0.268   0.461   0.390   0.153
177   Y         0.489   0.333   0.274   0.849   0.658   0.534   0.461   0.222   0.118
178   Y         0.185   0.206   0.176   0.313   0.386   0.296  -0.033   0.015  -0.043
179   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   K        -0.427  -0.439  -0.440  -0.450  -0.469  -0.506  -0.526  -0.535  -0.520
181   G        -1.323  -1.335  -1.293  -1.455  -1.456  -1.359  -1.019  -1.020  -0.954
182   S        -1.323  -1.343  -1.274  -1.337  -1.364  -1.262  -1.019  -1.026  -0.939
183   D        -0.427  -0.499  -0.449  -0.296  -0.398  -0.315  -0.526  -0.592  -0.528
184   S        -0.427  -0.387  -0.429  -0.478  -0.433  -0.509  -0.526  -0.475  -0.509
185   I         0.093   0.105   0.129  -0.038   0.002   0.036  -0.197  -0.177  -0.136
186   V        -0.427  -0.470  -0.441  -0.541  -0.632  -0.586  -0.526  -0.560  -0.520
187   I         0.705   0.726   0.795   0.542   0.590   0.676   0.296   0.324   0.413
188   Q         0.489   0.376   0.289   0.715   0.557   0.431   0.461   0.286   0.143
189   S         1.224   1.238   1.103   1.212   1.225   1.070   1.283   1.301   1.039
190   D         1.224   1.111   1.089   1.398   1.237   1.222   1.283   1.078   1.011
191   E        -0.804  -0.833  -0.866  -0.826  -0.934  -0.996  -0.690  -0.720  -0.736
192   T         0.489   0.498   0.322   0.654   0.678   0.402   0.461   0.471   0.194
193   R         2.005   2.036   2.118   1.954   2.008   2.134   2.269   2.315   2.463
194   S         0.866   0.955   0.935   0.666   0.799   0.767   0.625   0.787   0.707
195   R         0.866   0.796   0.845   0.726   0.597   0.669   0.625   0.469   0.520
196   E        -0.192  -0.271  -0.336   0.061  -0.040  -0.129  -0.197  -0.304  -0.380
197   T        -0.427  -0.425  -0.422  -0.387  -0.436  -0.383  -0.526  -0.510  -0.500
198   N         2.005   2.036   2.118   2.085   2.139   2.267   2.269   2.315   2.463
199   K        -0.946  -0.970  -0.923  -1.036  -1.042  -1.020  -0.855  -0.867  -0.796
200   L        -0.427  -0.338  -0.404  -0.434  -0.290  -0.402  -0.526  -0.407  -0.478
201   K        -0.946  -0.842  -0.889  -1.018  -0.842  -0.944  -0.855  -0.748  -0.767
202   C         1.224   1.111   1.089   1.584   1.454   1.415   1.283   1.078   1.011
203   F         0.185   0.188   0.140   0.200   0.207   0.110  -0.033  -0.053  -0.110
204   E        -0.804  -0.804  -0.841  -0.627  -0.630  -0.692  -0.690  -0.688  -0.710
205   K         0.866   0.880   0.874   0.391   0.395   0.377   0.625   0.641   0.580
206   L         1.224   1.111   1.089   1.276   1.127   1.097   1.283   1.078   1.011
207   V        -0.192  -0.271  -0.336   0.035  -0.090  -0.195  -0.197  -0.304  -0.380
208   Q        -1.323  -1.343  -1.274  -1.265  -1.299  -1.216  -1.019  -1.026  -0.939
209   E         0.489   0.333   0.274   0.659   0.437   0.349   0.461   0.222   0.118
210   I         0.185   0.175   0.133   0.160   0.115   0.065  -0.033  -0.077  -0.118
211   R        -0.427  -0.495  -0.450  -0.774  -0.863  -0.767  -0.526  -0.595  -0.534
212   Q        -0.569  -0.530  -0.495  -0.856  -0.855  -0.753  -0.690  -0.644  -0.586
213   T        -1.323  -1.313  -1.282  -1.359  -1.364  -1.336  -1.019  -1.002  -0.946
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   C        -0.569  -0.572  -0.498  -0.485  -0.477  -0.385  -0.690  -0.680  -0.588
217   Q        -0.946  -0.872  -0.898  -0.838  -0.723  -0.758  -0.855  -0.773  -0.775
218   F         0.489   0.333   0.274   0.771   0.612   0.490   0.461   0.222   0.118
219   P        -0.427  -0.499  -0.449  -0.208  -0.297  -0.230  -0.526  -0.592  -0.528
220   N        -0.804  -0.833  -0.848  -0.569  -0.612  -0.661  -0.690  -0.720  -0.717
221   D        -0.427  -0.469  -0.446  -0.339  -0.391  -0.347  -0.526  -0.569  -0.530
222   T        -0.192  -0.194  -0.316   0.081   0.087  -0.084  -0.197  -0.198  -0.354
223   T        -0.804  -0.804  -0.857  -0.702  -0.706  -0.760  -0.690  -0.689  -0.727
224   A        -0.946  -0.931  -0.896  -0.680  -0.662  -0.579  -0.855  -0.833  -0.773
225   E         0.489   0.543   0.321   0.643   0.726   0.398   0.461   0.542   0.192
226   T        -0.427  -0.499  -0.449  -0.513  -0.679  -0.598  -0.526  -0.592  -0.528
227   S        -0.427  -0.405  -0.447  -0.760  -0.704  -0.754  -0.526  -0.509  -0.531
228   K        -1.323  -1.343  -1.274  -1.501  -1.491  -1.405  -1.019  -1.026  -0.939
229   K         0.866   0.849   0.865   0.391   0.341   0.362   0.625   0.578   0.563
230   W         1.224   1.111   1.089   1.577   1.433   1.395   1.283   1.078   1.011
231   N        -0.569  -0.592  -0.502  -0.601  -0.657  -0.504  -0.690  -0.698  -0.591
232   K        -0.427  -0.495  -0.450  -0.670  -0.792  -0.749  -0.526  -0.595  -0.534
233   I         0.866   0.840   0.859   0.789   0.743   0.735   0.625   0.559   0.550
234   K         0.489   0.498   0.322   0.295   0.296   0.078   0.461   0.471   0.194
235   E         0.185   0.315   0.182  -0.181  -0.013  -0.171  -0.033   0.163  -0.041
236   K        -0.946  -0.962  -0.914  -1.128  -1.178  -1.087  -0.855  -0.858  -0.788
237   A        -1.323  -1.259  -1.263  -1.180  -1.101  -1.078  -1.019  -0.952  -0.930
238   N         0.185   0.206   0.176   0.036   0.108   0.024  -0.033   0.015  -0.043
239   K         0.705   0.726   0.797   0.256   0.274   0.371   0.296   0.324   0.418
240   E        -0.804  -0.687  -0.810  -1.008  -0.848  -1.008  -0.690  -0.552  -0.677
241   R         1.224   1.300   1.123   1.184   1.299   1.015   1.283   1.404   1.076
242   L         1.224   1.300   1.123   1.210   1.319   1.042   1.283   1.404   1.076
243   L        -0.946  -0.925  -0.909  -0.920  -0.876  -0.864  -0.855  -0.823  -0.784
244   D        -0.946  -0.925  -0.909  -0.766  -0.726  -0.690  -0.855  -0.823  -0.784
245   K         2.005   2.036   2.118   1.666   1.694   1.843   2.269   2.315   2.463
246   K         1.224   1.238   1.103   0.941   0.947   0.771   1.283   1.301   1.039
247   V        -1.323  -1.296  -1.263  -1.241  -1.146  -1.150  -1.019  -0.987  -0.930
248   H        -0.946  -0.925  -0.909  -1.015  -1.051  -0.950  -0.855  -0.823  -0.784
249   S         1.224   1.111   1.089   1.197   1.031   1.022   1.283   1.078   1.011
250   D        -0.192  -0.332  -0.367  -0.048  -0.319  -0.371  -0.197  -0.377  -0.419
251   K         2.005   2.036   2.118   1.666   1.694   1.843   2.269   2.315   2.463
252   K         2.005   2.036   2.118   1.666   1.694   1.843   2.269   2.315   2.463
253   K        -0.804  -0.881  -0.864  -1.081  -1.207  -1.173  -0.690  -0.769  -0.734
254   N        -1.323  -1.335  -1.269  -0.982  -1.006  -0.893  -1.019  -1.020  -0.935
255   R         2.005   2.036   2.118   1.954   2.008   2.134   2.269   2.315   2.463
256   S        -0.427  -0.418  -0.439  -0.703  -0.721  -0.748  -0.526  -0.522  -0.522
257   K        -0.192  -0.288  -0.352  -0.339  -0.480  -0.537  -0.197  -0.324  -0.400
258   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   K        -0.192  -0.233  -0.319  -0.406  -0.486  -0.590  -0.197  -0.255  -0.358
260   F        -0.427  -0.516  -0.445  -0.300  -0.361  -0.297  -0.526  -0.616  -0.526
261   N         0.489   0.517   0.317   0.704   0.738   0.456   0.461   0.499   0.186
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   Y        -0.527  -0.478  -0.479  -0.317  -0.231  -0.234  -0.640  -0.581  -0.565
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12322
Output conservation file - output/Q12322
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
