1     M         1.144   1.175   1.217   1.331   1.371   1.436   1.219   1.258   1.324
2     K        -0.422  -0.640  -0.724  -0.278  -0.575  -0.693  -0.402  -0.677  -0.793
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     Y         0.337   0.273   0.064   0.620   0.545   0.209   0.335   0.240  -0.123
9     I        -0.032  -0.039  -0.038  -0.138  -0.143  -0.151  -0.254  -0.268  -0.304
10    I         0.337   0.175   0.066   0.376   0.181   0.011   0.335   0.088  -0.120
11    E         1.144   1.175   1.217   0.974   1.013   1.108   1.219   1.258   1.324
12    H         1.144   1.175   1.217   1.421   1.461   1.518   1.219   1.258   1.324
13    M         0.337   0.175   0.066   0.584   0.344   0.097   0.335   0.088  -0.120
14    E         0.337   0.175   0.066   0.241   0.007  -0.176   0.335   0.088  -0.120
15    E         0.337   0.401   0.071   0.296   0.377  -0.037   0.335   0.429  -0.112
16    G         0.337   0.175   0.066   0.422   0.182  -0.027   0.335   0.088  -0.120
17    F         0.337   0.175   0.066   0.500   0.259   0.024   0.335   0.088  -0.120
18    S         0.337   0.175   0.066   0.518   0.295   0.103   0.335   0.088  -0.120
19    E        -0.422  -0.640  -0.724  -0.446  -0.764  -0.911  -0.402  -0.677  -0.793
20    W         1.144   1.175   1.217   1.435   1.481   1.531   1.219   1.258   1.324
21    V         0.337   0.175   0.066   0.573   0.341   0.167   0.335   0.088  -0.120
22    I        -1.367  -1.467  -1.304  -1.456  -1.609  -1.396  -1.286  -1.347  -1.144
23    L         1.144   1.175   1.217   0.903   0.967   1.044   1.219   1.258   1.324
24    E         1.144   1.175   1.217   0.974   1.013   1.108   1.219   1.258   1.324
25    Y         1.144   1.175   1.217   1.312   1.358   1.419   1.219   1.258   1.324
26    S        -1.367  -1.361  -1.284  -1.223  -1.249  -1.166  -1.286  -1.250  -1.126
27    Q        -0.032  -0.129  -0.037   0.107  -0.062   0.049  -0.254  -0.425  -0.302
28    I         1.144   1.175   1.217   1.062   1.123   1.190   1.219   1.258   1.324
29    L        -0.978  -0.940  -0.795  -1.232  -1.115  -0.951  -1.138  -1.077  -0.883
30    R        -0.735  -0.817  -0.759  -0.684  -0.821  -0.756  -0.844  -0.931  -0.842
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    E        -0.199  -0.181  -0.056  -0.641  -0.627  -0.410  -0.549  -0.520  -0.336
35    V        -0.199  -0.182  -0.056  -0.359  -0.351  -0.161  -0.549  -0.520  -0.336
36    G         1.144   1.175   1.217   1.157   1.197   1.277   1.219   1.258   1.324
37    A        -1.367  -1.259  -1.298  -1.232  -1.119  -1.086  -1.286  -1.175  -1.139
38    E        -0.199  -0.181  -0.056  -0.641  -0.627  -0.410  -0.549  -0.520  -0.336
39    N         0.258   0.052   0.020   0.530   0.218   0.095   0.216  -0.113  -0.201
40    L        -0.032  -0.129  -0.037  -0.298  -0.430  -0.282  -0.254  -0.425  -0.302
41    I        -1.124  -1.237  -1.277  -0.952  -1.055  -1.167  -0.991  -1.107  -1.116
42    L         1.144   1.175   1.217   0.903   0.967   1.044   1.219   1.258   1.324
43    S        -0.199  -0.164  -0.055  -0.352  -0.296  -0.134  -0.549  -0.488  -0.334
44    S         1.144   1.175   1.217   1.224   1.264   1.338   1.219   1.258   1.324
45    L         1.144   1.175   1.217   0.903   0.967   1.044   1.219   1.258   1.324
46    P         1.144   1.175   1.217   1.195   1.230   1.311   1.219   1.258   1.324
47    E        -1.756  -1.814  -1.719  -1.634  -1.708  -1.553  -1.433  -1.464  -1.318
48    S        -0.831  -0.762  -0.756  -0.893  -0.797  -0.797  -0.991  -0.887  -0.839
49    T        -0.422  -0.540  -0.692  -0.240  -0.395  -0.665  -0.402  -0.554  -0.751
50    T        -0.724  -0.691  -0.767  -0.571  -0.521  -0.630  -0.802  -0.744  -0.847
51    E         0.160   0.208   0.003   0.010   0.078  -0.273   0.064   0.139  -0.230
52    K        -0.179  -0.148  -0.050  -0.351  -0.304  -0.153  -0.514  -0.459  -0.326
53    D        -0.422  -0.640  -0.724  -0.448  -0.780  -0.955  -0.402  -0.677  -0.793
54    I        -0.422  -0.640  -0.724  -0.361  -0.655  -0.849  -0.402  -0.677  -0.793
55    P         1.144   1.175   1.217   1.195   1.230   1.311   1.219   1.258   1.324
56    Q        -1.367  -1.217  -1.279  -1.435  -1.233  -1.259  -1.286  -1.100  -1.120
57    R        -1.756  -1.810  -1.713  -1.550  -1.623  -1.595  -1.433  -1.461  -1.314
58    L         1.144   1.175   1.217   0.903   0.967   1.044   1.219   1.258   1.324
59    L        -1.514  -1.530  -1.313  -1.654  -1.611  -1.338  -1.433  -1.408  -1.153
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    K        -0.735  -0.634  -0.740  -0.920  -0.752  -0.966  -0.844  -0.689  -0.816
66    L        -0.978  -0.956  -0.798  -1.129  -1.060  -0.830  -1.138  -1.094  -0.886
67    G        -0.032  -0.129  -0.037  -0.160  -0.375  -0.245  -0.254  -0.425  -0.302
68    L        -0.422  -0.640  -0.724  -0.423  -0.671  -0.765  -0.402  -0.677  -0.793
69    R        -0.735  -0.680  -0.743  -0.569  -0.499  -0.636  -0.844  -0.781  -0.822
70    W        -0.032  -0.129  -0.037   0.171  -0.029   0.068  -0.254  -0.425  -0.302
71    T         0.337   0.175   0.066   0.470   0.263   0.091   0.335   0.088  -0.120
72    T        -0.032  -0.129  -0.037  -0.160  -0.366  -0.245  -0.254  -0.425  -0.302
73    K        -1.367  -1.393  -1.291  -1.434  -1.505  -1.311  -1.286  -1.289  -1.133
74    D        -1.299  -1.129  -1.282  -1.286  -1.044  -1.254  -1.187  -0.974  -1.121
75    L        -0.845  -0.933  -0.782  -0.982  -1.100  -0.874  -0.987  -1.063  -0.868
76    K        -2.379  -2.295  -2.076  -2.251  -2.131  -1.846  -1.789  -1.689  -1.446
77    G        -1.470  -1.362  -1.300  -1.534  -1.375  -1.257  -1.388  -1.251  -1.141
78    I         0.258   0.052   0.020   0.241  -0.033  -0.099   0.216  -0.113  -0.201
79    N        -1.470  -1.481  -1.319  -1.463  -1.522  -1.271  -1.388  -1.370  -1.159
80    E        -0.845  -0.933  -0.782  -1.042  -1.164  -0.927  -0.987  -1.063  -0.868
81    D        -1.470  -1.475  -1.320  -1.343  -1.341  -1.157  -1.388  -1.365  -1.159
82    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    L        -0.930  -0.834  -0.788  -1.133  -0.969  -0.862  -1.091  -0.959  -0.876
86    E        -0.930  -0.949  -0.776  -1.088  -1.083  -0.819  -1.091  -1.085  -0.860
87    L        -2.379  -2.322  -2.076  -2.178  -2.043  -1.780  -1.789  -1.710  -1.446
88    L        -1.367  -1.468  -1.309  -1.507  -1.578  -1.339  -1.286  -1.349  -1.149
89    K        -1.367  -1.222  -1.283  -1.485  -1.274  -1.346  -1.286  -1.104  -1.124
90    D        -1.124  -0.913  -1.250  -0.949  -0.666  -1.138  -0.991  -0.731  -1.088
91    G        -0.735  -0.594  -0.737  -0.628  -0.405  -0.628  -0.844  -0.633  -0.811
92    R        -0.032   0.059   0.003  -0.057   0.095  -0.051  -0.254  -0.102  -0.231
93    V         0.337   0.392   0.071   0.547   0.607   0.114   0.335   0.416  -0.111
94    C         1.144   1.175   1.217   1.449   1.493   1.544   1.219   1.258   1.324
95    L         1.144   1.175   1.217   0.903   0.967   1.044   1.219   1.258   1.324
96    L         1.144   1.175   1.217   0.903   0.967   1.044   1.219   1.258   1.324
97    D         1.144   1.175   1.217   1.001   1.044   1.133   1.219   1.258   1.324
98    P         1.144   1.175   1.217   1.195   1.230   1.311   1.219   1.258   1.324
99    R        -0.831  -0.846  -0.761  -0.748  -0.754  -0.634  -0.991  -0.974  -0.844
100   A         1.144   1.175   1.217   1.287   1.318   1.396   1.219   1.258   1.324
101   T        -0.735  -0.687  -0.745  -0.932  -0.904  -0.936  -0.844  -0.799  -0.826
102   I        -2.293  -2.265  -2.064  -2.251  -2.227  -1.983  -1.728  -1.674  -1.438
103   D        -0.422  -0.454  -0.696  -0.432  -0.473  -0.871  -0.402  -0.435  -0.757
104   L         1.144   1.175   1.217   0.903   0.967   1.044   1.219   1.258   1.324
105   Q        -1.903  -1.777  -1.726  -1.613  -1.433  -1.409  -1.580  -1.436  -1.324
106   P         1.144   1.175   1.217   1.195   1.230   1.311   1.219   1.258   1.324
107   E        -0.422  -0.279  -0.680  -0.374  -0.196  -0.700  -0.402  -0.207  -0.735
108   D         1.144   1.175   1.217   1.001   1.044   1.133   1.219   1.258   1.324
109   A        -1.903  -1.759  -1.725  -1.647  -1.461  -1.420  -1.580  -1.424  -1.323
110   T        -1.903  -1.750  -1.720  -1.852  -1.660  -1.560  -1.580  -1.419  -1.320
111   K        -1.756  -1.746  -1.689  -1.534  -1.537  -1.450  -1.433  -1.401  -1.294
112   F         0.337   0.401   0.071   0.566   0.646   0.190   0.335   0.429  -0.112
113   D         1.144   1.175   1.217   1.001   1.044   1.133   1.219   1.258   1.324
114   Y        -0.422  -0.640  -0.724  -0.083  -0.391  -0.591  -0.402  -0.677  -0.793
115   F         1.144   1.175   1.217   1.246   1.286   1.358   1.219   1.258   1.324
116   V        -0.032  -0.129  -0.037  -0.078  -0.311  -0.196  -0.254  -0.425  -0.302
117   F         1.144   1.175   1.217   1.246   1.286   1.358   1.219   1.258   1.324
118   G         1.144   1.175   1.217   1.157   1.197   1.277   1.219   1.258   1.324
119   G         1.144   1.175   1.217   1.157   1.197   1.277   1.219   1.258   1.324
120   I         1.144   1.175   1.217   1.062   1.123   1.190   1.219   1.258   1.324
121   L         1.144   1.175   1.217   0.903   0.967   1.044   1.219   1.258   1.324
122   G         1.144   1.175   1.217   1.157   1.197   1.277   1.219   1.258   1.324
123   D        -0.032   0.059   0.003  -0.213  -0.076  -0.161  -0.254  -0.102  -0.231
124   H         0.337   0.175   0.066   0.689   0.451   0.211   0.335   0.088  -0.120
125   P         1.144   1.175   1.217   1.195   1.230   1.311   1.219   1.258   1.324
126   P        -0.032   0.059   0.003  -0.030   0.106  -0.005  -0.254  -0.102  -0.231
127   R        -0.032   0.059   0.003  -0.063   0.098  -0.058  -0.254  -0.102  -0.231
128   D         1.144   1.175   1.217   1.001   1.044   1.133   1.219   1.258   1.324
129   R         1.144   1.175   1.217   1.224   1.272   1.338   1.219   1.258   1.324
130   T         1.144   1.175   1.217   1.157   1.206   1.277   1.219   1.258   1.324
131   K        -1.367  -1.378  -1.290  -1.307  -1.301  -1.184  -1.286  -1.260  -1.130
132   E        -0.422  -0.287  -0.685  -0.494  -0.300  -0.942  -0.402  -0.217  -0.741
133   L         1.144   1.175   1.217   0.903   0.967   1.044   1.219   1.258   1.324
134   K        -1.124  -0.913  -1.250  -0.765  -0.480  -0.965  -0.991  -0.731  -1.088
135   T        -1.367  -1.170  -1.279  -1.501  -1.194  -1.374  -1.286  -1.053  -1.120
136   A        -1.367  -1.320  -1.285  -1.206  -1.137  -1.057  -1.286  -1.198  -1.125
137   Y         1.144   1.175   1.217   1.312   1.355   1.419   1.219   1.258   1.324
138   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   L        -0.199  -0.119  -0.041  -0.550  -0.378  -0.296  -0.549  -0.408  -0.309
141   L        -0.199  -0.189  -0.057  -0.546  -0.495  -0.288  -0.549  -0.533  -0.338
142   I        -1.903  -1.849  -1.715  -1.676  -1.651  -1.466  -1.580  -1.506  -1.316
143   S         0.337   0.471   0.077   0.463   0.625   0.091   0.335   0.526  -0.101
144   R         0.337   0.401   0.071   0.505   0.595   0.081   0.335   0.429  -0.112
145   R         0.337   0.273   0.064   0.554   0.489   0.186   0.335   0.240  -0.123
146   L         1.144   1.175   1.217   0.903   0.967   1.044   1.219   1.258   1.324
147   G         0.337   0.273   0.064   0.426   0.336  -0.019   0.335   0.240  -0.123
148   D        -1.367  -1.468  -1.309  -1.405  -1.544  -1.307  -1.286  -1.349  -1.149
149   K        -1.367  -1.468  -1.309  -1.453  -1.557  -1.323  -1.286  -1.349  -1.149
150   Q         1.144   1.175   1.217   1.316   1.371   1.422   1.219   1.258   1.324
151   M         1.144   1.175   1.217   1.331   1.371   1.436   1.219   1.258   1.324
152   T         1.144   1.175   1.217   1.157   1.206   1.277   1.219   1.258   1.324
153   T         1.144   1.175   1.217   1.157   1.206   1.277   1.219   1.258   1.324
154   D         1.144   1.175   1.217   1.001   1.044   1.133   1.219   1.258   1.324
155   T         1.144   1.175   1.217   1.157   1.206   1.277   1.219   1.258   1.324
156   A         1.144   1.175   1.217   1.287   1.318   1.396   1.219   1.258   1.324
157   I        -0.032  -0.129  -0.037  -0.138  -0.289  -0.150  -0.254  -0.425  -0.302
158   R         1.144   1.175   1.217   1.224   1.272   1.338   1.219   1.258   1.324
159   T        -0.032  -0.129  -0.037  -0.048  -0.217  -0.079  -0.254  -0.425  -0.302
160   T         1.144   1.175   1.217   1.157   1.206   1.277   1.219   1.258   1.324
161   Q        -0.422  -0.640  -0.724  -0.085  -0.387  -0.601  -0.402  -0.677  -0.793
162   L        -1.367  -1.275  -1.281  -1.574  -1.437  -1.414  -1.286  -1.176  -1.124
163   I        -0.032  -0.129  -0.037  -0.138  -0.289  -0.150  -0.254  -0.425  -0.302
164   I        -0.199  -0.188  -0.057  -0.401  -0.371  -0.163  -0.549  -0.531  -0.337
165   K        -0.831  -0.847  -0.755  -1.139  -1.166  -1.013  -0.991  -0.975  -0.837
166   D        -1.124  -1.144  -1.248  -1.021  -1.071  -1.189  -0.991  -1.005  -1.086
167   R        -1.367  -1.259  -1.295  -1.193  -1.098  -1.122  -1.286  -1.174  -1.136
168   I        -1.514  -1.434  -1.305  -1.536  -1.427  -1.255  -1.433  -1.333  -1.146
169   A        -0.978  -0.940  -0.796  -1.070  -1.033  -0.799  -1.138  -1.076  -0.884
170   F        -0.422  -0.640  -0.724  -0.148  -0.459  -0.641  -0.402  -0.677  -0.793
171   E        -0.032  -0.129  -0.037  -0.328  -0.525  -0.374  -0.254  -0.425  -0.302
172   D        -0.735  -0.772  -0.765  -0.890  -0.982  -0.913  -0.844  -0.899  -0.847
173   I         0.337   0.401   0.071   0.376   0.475   0.018   0.335   0.429  -0.112
174   K        -0.735  -0.772  -0.765  -0.822  -0.907  -0.899  -0.844  -0.899  -0.847
175   F        -0.032  -0.129  -0.037   0.052  -0.115   0.012  -0.254  -0.425  -0.302
176   I        -0.978  -0.957  -0.798  -1.242  -1.165  -0.967  -1.138  -1.096  -0.887
177   D         1.144   1.175   1.217   1.001   1.044   1.133   1.219   1.258   1.324
178   Y         0.337   0.175   0.066   0.649   0.453   0.280   0.335   0.088  -0.120
179   P         1.144   1.175   1.217   1.195   1.230   1.311   1.219   1.258   1.324
180   E         1.144   1.175   1.217   0.974   1.013   1.108   1.219   1.258   1.324
181   F        -0.978  -0.957  -0.798  -1.204  -1.209  -0.980  -1.138  -1.096  -0.887
182   R        -0.199  -0.189  -0.057  -0.387  -0.396  -0.188  -0.549  -0.533  -0.338
183   F        -0.032   0.059   0.003   0.052   0.187   0.078  -0.254  -0.102  -0.231
184   N        -0.199  -0.189  -0.057  -0.176  -0.177   0.006  -0.549  -0.533  -0.338
185   K         0.337   0.175   0.066   0.342   0.102  -0.096   0.335   0.088  -0.120
186   N        -1.367  -1.359  -1.290  -1.009  -0.968  -0.923  -1.286  -1.248  -1.131
187   E         1.144   1.175   1.217   0.974   1.013   1.108   1.219   1.258   1.324
188   A        -0.199  -0.189  -0.057  -0.246  -0.256  -0.050  -0.549  -0.533  -0.338
189   T         1.144   1.175   1.217   1.157   1.206   1.277   1.219   1.258   1.324
190   E         0.337   0.175   0.066   0.296   0.094  -0.044   0.335   0.088  -0.120
191   M         1.144   1.175   1.217   1.331   1.371   1.436   1.219   1.258   1.324
192   P         1.144   1.175   1.217   1.195   1.230   1.311   1.219   1.258   1.324
193   F         1.144   1.175   1.217   1.246   1.286   1.358   1.219   1.258   1.324
194   R         1.144   1.175   1.217   1.224   1.272   1.338   1.219   1.258   1.324
195   Y         1.144   1.175   1.217   1.312   1.358   1.419   1.219   1.258   1.324
196   V         0.337   0.392   0.071   0.547   0.607   0.114   0.335   0.416  -0.111
197   L        -1.367  -1.241  -1.283  -1.384  -1.146  -1.229  -1.286  -1.116  -1.123
198   D        -0.422  -0.340  -0.686  -0.349  -0.239  -0.690  -0.402  -0.283  -0.744
199   K        -1.367  -1.304  -1.276  -1.232  -1.153  -1.065  -1.286  -1.190  -1.117
200   E        -0.735  -0.610  -0.740  -0.929  -0.757  -0.904  -0.844  -0.674  -0.817
201   G         0.337   0.392   0.071   0.426   0.498  -0.006   0.335   0.416  -0.111
202   K        -1.367  -1.245  -1.279  -1.165  -1.009  -1.015  -1.286  -1.121  -1.120
203   P         1.144   1.175   1.217   1.195   1.230   1.311   1.219   1.258   1.324
204   I         1.144   1.175   1.217   1.062   1.123   1.190   1.219   1.258   1.324
205   L        -0.032  -0.129  -0.037  -0.263  -0.382  -0.232  -0.254  -0.425  -0.302
206   P         1.144   1.175   1.217   1.195   1.230   1.311   1.219   1.258   1.324
207   E        -0.422  -0.640  -0.724  -0.411  -0.714  -0.835  -0.402  -0.677  -0.793
208   G         1.144   1.175   1.217   1.157   1.197   1.277   1.219   1.258   1.324
209   M         1.144   1.175   1.217   1.331   1.371   1.436   1.219   1.258   1.324
210   L        -0.422  -0.640  -0.724  -0.450  -0.719  -0.822  -0.402  -0.677  -0.793
211   D        -0.735  -0.570  -0.738  -0.854  -0.620  -0.859  -0.844  -0.617  -0.813
212   L         1.144   1.175   1.217   0.903   0.967   1.044   1.219   1.258   1.324
213   I         1.144   1.175   1.217   1.062   1.123   1.190   1.219   1.258   1.324
214   K         1.144   1.175   1.217   1.078   1.116   1.204   1.219   1.258   1.324
215   K        -1.124  -1.078  -1.253  -0.821  -0.768  -0.941  -0.991  -0.922  -1.091
216   D         1.144   1.175   1.217   1.001   1.044   1.133   1.219   1.258   1.324
217   S        -0.032   0.059   0.003   0.021   0.154   0.049  -0.254  -0.102  -0.231
218   A        -1.124  -1.092  -1.246  -1.049  -1.056  -1.209  -0.991  -0.951  -1.085
219   Q        -0.032  -0.129  -0.037   0.030  -0.165  -0.065  -0.254  -0.425  -0.302
220   S         0.337   0.175   0.066   0.540   0.326   0.154   0.335   0.088  -0.120
221   L        -0.199  -0.182  -0.056  -0.667  -0.615  -0.420  -0.549  -0.521  -0.335
222   D         1.144   1.175   1.217   1.001   1.044   1.133   1.219   1.258   1.324
223   D         1.144   1.175   1.217   1.001   1.044   1.133   1.219   1.258   1.324
224   L        -0.032  -0.129  -0.037  -0.263  -0.382  -0.232  -0.254  -0.425  -0.302
225   L        -0.032  -0.085  -0.043  -0.298  -0.364  -0.289  -0.254  -0.348  -0.313
226   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12314
Output conservation file - output/Q12314
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
