1     M         1.104   1.111   1.144   1.343   1.356   1.392   1.183   1.192   1.240
2     S        -0.268  -0.167  -0.551  -0.134  -0.004  -0.489  -0.276  -0.140  -0.662
3     S        -0.543  -0.541  -0.617  -0.403  -0.430  -0.537  -0.674  -0.688  -0.758
4     D        -0.688  -0.607  -0.635  -0.799  -0.660  -0.723  -0.848  -0.737  -0.775
5     T        -0.688  -0.607  -0.634  -0.779  -0.630  -0.700  -0.848  -0.737  -0.775
6     S        -0.688  -0.607  -0.634  -0.917  -0.763  -0.838  -0.848  -0.737  -0.775
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    E         0.135   0.010   0.038   0.359   0.169   0.198  -0.036  -0.258  -0.234
23    S        -1.192  -1.156  -1.117  -1.391  -1.325  -1.286  -1.157  -1.115  -1.051
24    S        -1.192  -1.135  -1.130  -1.024  -0.931  -0.937  -1.157  -1.091  -1.065
25    L        -1.192  -1.135  -1.130  -1.058  -0.948  -0.997  -1.157  -1.091  -1.065
26    L        -1.192  -1.216  -1.138  -1.255  -1.280  -1.169  -1.157  -1.181  -1.073
27    K        -1.192  -1.157  -1.115  -0.953  -0.905  -0.823  -1.157  -1.116  -1.049
28    E        -1.192  -1.157  -1.115  -1.034  -0.975  -0.939  -1.157  -1.116  -1.049
29    E        -0.688  -0.662  -0.634  -0.616  -0.569  -0.558  -0.848  -0.811  -0.775
30    S        -1.285  -1.281  -1.149  -1.386  -1.380  -1.171  -1.255  -1.247  -1.083
31    G        -0.688  -0.673  -0.652  -0.892  -0.864  -0.869  -0.848  -0.826  -0.797
32    S        -0.091  -0.085  -0.002  -0.563  -0.557  -0.399  -0.442  -0.434  -0.309
33    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    K        -1.226  -1.219  -1.137  -1.474  -1.473  -1.309  -1.205  -1.194  -1.072
42    S        -1.909  -1.936  -1.816  -1.766  -1.846  -1.699  -1.470  -1.487  -1.339
43    N        -0.885  -0.867  -1.066  -0.712  -0.682  -0.932  -0.807  -0.784  -0.998
44    P        -1.439  -1.402  -1.457  -1.440  -1.388  -1.433  -1.205  -1.166  -1.186
45    V        -1.097  -1.153  -1.110  -1.195  -1.288  -1.229  -1.072  -1.123  -1.046
46    R        -1.567  -1.540  -1.498  -1.582  -1.551  -1.492  -1.338  -1.312  -1.223
47    E        -0.756  -0.745  -0.664  -0.712  -0.706  -0.598  -0.940  -0.925  -0.813
48    N         0.073   0.032   0.022   0.261   0.193   0.146  -0.144  -0.218  -0.263
49    I        -1.567  -1.550  -1.492  -1.599  -1.565  -1.450  -1.338  -1.318  -1.218
50    K        -0.268  -0.343  -0.579  -0.039  -0.134  -0.448  -0.276  -0.379  -0.700
51    S         0.397   0.411   0.130   0.381   0.403  -0.056   0.387   0.408  -0.067
52    F         0.073   0.079   0.042   0.022   0.035  -0.065  -0.144  -0.134  -0.227
53    V        -0.073  -0.081  -0.002  -0.497  -0.523  -0.362  -0.409  -0.427  -0.308
54    A         0.397   0.454   0.130   0.280   0.347  -0.117   0.387   0.471  -0.067
55    G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
56    G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
57    V        -0.073  -0.069   0.001  -0.293  -0.287  -0.178  -0.409  -0.403  -0.302
58    G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
59    G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
60    V        -0.073  -0.044   0.013  -0.305  -0.257  -0.157  -0.409  -0.357  -0.280
61    C         1.104   1.111   1.144   1.418   1.430   1.462   1.183   1.192   1.240
62    A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
63    V         1.104   1.111   1.144   1.038   1.045   1.105   1.183   1.192   1.240
64    F        -0.268  -0.363  -0.568  -0.194  -0.331  -0.661  -0.276  -0.404  -0.686
65    T         0.073   0.032   0.022  -0.024  -0.101  -0.153  -0.144  -0.218  -0.263
66    G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
67    H         1.104   1.111   1.144   1.412   1.422   1.456   1.183   1.192   1.240
68    P         1.104   1.111   1.144   1.240   1.251   1.295   1.183   1.192   1.240
69    F         1.104   1.111   1.144   1.169   1.182   1.228   1.183   1.192   1.240
70    D         1.104   1.111   1.144   1.306   1.318   1.356   1.183   1.192   1.240
71    L         1.104   1.111   1.144   1.076   1.089   1.141   1.183   1.192   1.240
72    I        -0.543  -0.617  -0.619  -0.671  -0.792  -0.804  -0.674  -0.760  -0.757
73    K         1.104   1.111   1.144   1.146   1.158   1.207   1.183   1.192   1.240
74    V         1.104   1.111   1.144   1.038   1.045   1.105   1.183   1.192   1.240
75    R         1.104   1.111   1.144   1.315   1.324   1.365   1.183   1.192   1.240
76    C        -0.073  -0.069   0.001  -0.132  -0.122  -0.001  -0.409  -0.403  -0.302
77    Q         1.104   1.111   1.144   1.301   1.310   1.352   1.183   1.192   1.240
78    N        -0.543  -0.543  -0.627  -0.552  -0.546  -0.655  -0.674  -0.672  -0.768
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    G         0.073   0.079   0.042  -0.081  -0.073  -0.104  -0.144  -0.134  -0.227
83    Q        -0.543  -0.576  -0.611  -0.458  -0.493  -0.600  -0.674  -0.700  -0.745
84    A        -0.073  -0.069   0.001  -0.212  -0.212  -0.115  -0.409  -0.403  -0.302
85    N        -1.097  -1.153  -1.110  -0.865  -0.944  -0.892  -1.072  -1.123  -1.046
86    S         0.073   0.032   0.022  -0.140  -0.220  -0.271  -0.144  -0.218  -0.263
87    T        -0.756  -0.723  -0.648  -1.107  -1.057  -0.917  -0.940  -0.895  -0.792
88    V        -0.627  -0.683  -0.632  -0.626  -0.687  -0.600  -0.807  -0.861  -0.776
89    H        -0.543  -0.500  -0.597  -0.274  -0.198  -0.328  -0.674  -0.605  -0.727
90    A        -0.756  -0.745  -0.664  -0.954  -0.968  -0.795  -0.940  -0.925  -0.813
91    I         0.397   0.396   0.128   0.414   0.412   0.034   0.387   0.385  -0.071
92    T        -1.097  -1.088  -1.115  -1.175  -1.153  -1.220  -1.072  -1.060  -1.051
93    N        -2.250  -2.238  -2.075  -1.815  -1.792  -1.573  -1.603  -1.591  -1.415
94    I        -0.543  -0.576  -0.611  -0.526  -0.557  -0.649  -0.674  -0.700  -0.745
95    I        -0.627  -0.612  -0.622  -0.673  -0.644  -0.606  -0.807  -0.788  -0.765
96    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   F        -1.567  -1.540  -1.498  -1.699  -1.665  -1.589  -1.338  -1.312  -1.223
115   T        -0.543  -0.541  -0.612  -0.565  -0.554  -0.683  -0.674  -0.668  -0.751
116   N        -0.073  -0.069   0.001  -0.002   0.008   0.106  -0.409  -0.403  -0.302
117   S        -0.543  -0.543  -0.626  -0.821  -0.824  -0.967  -0.674  -0.672  -0.766
118   V        -0.627  -0.613  -0.639  -0.813  -0.796  -0.772  -0.807  -0.791  -0.785
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   K        -1.097  -1.025  -1.099  -0.901  -0.795  -0.905  -1.072  -0.998  -1.035
121   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
122   F         0.073   0.049   0.025   0.022  -0.021  -0.099  -0.144  -0.188  -0.257
123   Y         1.104   1.111   1.144   1.341   1.352   1.390   1.183   1.192   1.240
124   K        -0.627  -0.682  -0.643  -0.634  -0.726  -0.682  -0.807  -0.860  -0.789
125   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
126   V         1.104   1.111   1.144   1.038   1.045   1.105   1.183   1.192   1.240
127   I        -1.567  -1.594  -1.508  -1.503  -1.540  -1.399  -1.338  -1.355  -1.230
128   P         0.073   0.032   0.022   0.036  -0.053  -0.128  -0.144  -0.218  -0.263
129   P         1.104   1.111   1.144   1.240   1.251   1.295   1.183   1.192   1.240
130   L         1.104   1.111   1.144   1.076   1.089   1.141   1.183   1.192   1.240
131   L        -0.543  -0.566  -0.624  -0.648  -0.698  -0.762  -0.674  -0.713  -0.764
132   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
133   V         1.104   1.111   1.144   1.038   1.045   1.105   1.183   1.192   1.240
134   T         1.104   1.111   1.144   1.137   1.150   1.198   1.183   1.192   1.240
135   P         1.104   1.111   1.144   1.240   1.251   1.295   1.183   1.192   1.240
136   I        -0.073  -0.069   0.001  -0.055  -0.045   0.047  -0.409  -0.403  -0.302
137   F         1.104   1.111   1.144   1.169   1.182   1.228   1.183   1.192   1.240
138   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
139   V         1.104   1.111   1.144   1.038   1.045   1.105   1.183   1.192   1.240
140   S         1.104   1.111   1.144   1.050   1.063   1.117   1.183   1.192   1.240
141   F         1.104   1.111   1.144   1.169   1.182   1.228   1.183   1.192   1.240
142   W         1.104   1.111   1.144   1.423   1.434   1.466   1.183   1.192   1.240
143   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
144   Y         1.104   1.111   1.144   1.341   1.352   1.390   1.183   1.192   1.240
145   D         1.104   1.111   1.144   1.306   1.318   1.356   1.183   1.192   1.240
146   V        -0.268  -0.350  -0.566  -0.219  -0.339  -0.663  -0.276  -0.387  -0.683
147   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
148   K         1.104   1.111   1.144   1.146   1.158   1.207   1.183   1.192   1.240
149   K        -0.756  -0.756  -0.668  -0.713  -0.711  -0.567  -0.940  -0.939  -0.818
150   L        -0.073  -0.075  -0.001  -0.274  -0.273  -0.148  -0.409  -0.415  -0.305
151   V         1.104   1.111   1.144   1.038   1.045   1.105   1.183   1.192   1.240
152   T        -0.543  -0.591  -0.623  -0.557  -0.598  -0.657  -0.674  -0.722  -0.763
153   F        -1.439  -1.462  -1.471  -1.327  -1.382  -1.363  -1.205  -1.228  -1.199
154   N        -1.909  -1.900  -1.801  -1.667  -1.662  -1.484  -1.470  -1.461  -1.329
155   N        -1.567  -1.561  -1.502  -1.409  -1.395  -1.256  -1.338  -1.326  -1.226
156   K        -1.909  -1.936  -1.816  -1.962  -1.996  -1.786  -1.470  -1.487  -1.339
157   Q        -1.226  -1.219  -1.136  -1.342  -1.334  -1.164  -1.205  -1.194  -1.072
158   G        -1.567  -1.520  -1.484  -1.560  -1.521  -1.434  -1.338  -1.296  -1.212
159   G        -1.439  -1.436  -1.473  -1.522  -1.520  -1.560  -1.205  -1.203  -1.201
160   S        -1.188  -1.134  -1.127  -1.231  -1.147  -1.146  -1.164  -1.112  -1.063
161   N        -0.688  -0.675  -0.637  -0.835  -0.814  -0.728  -0.848  -0.829  -0.777
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   E        -1.567  -1.532  -1.495  -1.230  -1.178  -1.146  -1.338  -1.306  -1.220
169   L        -0.073  -0.044   0.013  -0.290  -0.235  -0.143  -0.409  -0.357  -0.280
170   T        -0.627  -0.588  -0.635  -0.740  -0.693  -0.689  -0.807  -0.767  -0.780
171   M        -0.885  -0.885  -1.087  -0.630  -0.622  -0.946  -0.807  -0.804  -1.020
172   G        -0.885  -0.848  -1.057  -0.995  -0.951  -1.279  -0.807  -0.763  -0.988
173   Q        -0.268  -0.167  -0.551   0.114   0.242  -0.280  -0.276  -0.140  -0.662
174   M        -0.073  -0.069   0.001  -0.085  -0.074   0.034  -0.409  -0.403  -0.302
175   A        -0.073  -0.069   0.001  -0.463  -0.460  -0.338  -0.409  -0.403  -0.302
176   A        -0.073  -0.046   0.008  -0.432  -0.395  -0.284  -0.409  -0.360  -0.289
177   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
178   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
179   F         1.104   1.111   1.144   1.169   1.182   1.228   1.183   1.192   1.240
180   I        -0.268  -0.343  -0.579  -0.068  -0.169  -0.566  -0.276  -0.379  -0.700
181   S         1.104   1.111   1.144   1.050   1.063   1.117   1.183   1.192   1.240
182   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
183   I         1.104   1.111   1.144   1.195   1.209   1.252   1.183   1.192   1.240
184   P         1.104   1.111   1.144   1.240   1.251   1.295   1.183   1.192   1.240
185   T         0.397   0.298   0.114   0.537   0.418   0.157   0.387   0.233  -0.096
186   T         1.104   1.111   1.144   1.137   1.150   1.198   1.183   1.192   1.240
187   L         0.073   0.032   0.022  -0.124  -0.209  -0.263  -0.144  -0.218  -0.263
188   V         0.397   0.298   0.114   0.414   0.281   0.010   0.387   0.233  -0.096
189   T        -0.073  -0.044   0.013  -0.388  -0.321  -0.237  -0.409  -0.357  -0.280
190   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
191   P         1.104   1.111   1.144   1.240   1.251   1.295   1.183   1.192   1.240
192   T        -0.073  -0.069   0.001  -0.233  -0.222  -0.115  -0.409  -0.403  -0.302
193   E         1.104   1.111   1.144   1.319   1.329   1.369   1.183   1.192   1.240
194   R         1.104   1.111   1.144   1.315   1.324   1.365   1.183   1.192   1.240
195   V         0.073   0.109   0.031  -0.058  -0.001  -0.128  -0.144  -0.082  -0.246
196   K         1.104   1.111   1.144   1.146   1.158   1.207   1.183   1.192   1.240
197   V         1.104   1.111   1.144   1.038   1.045   1.105   1.183   1.192   1.240
198   V        -0.756  -0.745  -0.664  -0.832  -0.823  -0.676  -0.940  -0.925  -0.813
199   L         0.073   0.135   0.067   0.037   0.133   0.036  -0.144  -0.036  -0.180
200   Q         1.104   1.111   1.144   1.301   1.310   1.352   1.183   1.192   1.240
201   T        -1.097  -1.120  -1.120  -1.094  -1.123  -1.144  -1.072  -1.086  -1.055
202   S        -0.885  -0.885  -1.087  -0.537  -0.536  -0.883  -0.807  -0.804  -1.020
203   S        -1.188  -1.110  -1.131  -1.271  -1.190  -1.117  -1.164  -1.091  -1.066
204   -        -0.639  -0.622  -0.624  -0.620  -0.547  -0.564  -0.803  -0.766  -0.761
205   -        -1.586  -1.567  -1.497  -1.525  -1.492  -1.354  -1.345  -1.328  -1.221
206   K         1.104   1.111   1.144   1.146   1.158   1.207   1.183   1.192   1.240
207   -        -0.688  -0.691  -0.655  -0.771  -0.770  -0.745  -0.848  -0.857  -0.801
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   G        -1.909  -1.897  -1.812  -1.955  -1.952  -1.777  -1.470  -1.459  -1.336
217   S         0.073   0.032   0.022  -0.140  -0.220  -0.271  -0.144  -0.218  -0.263
218   F        -1.097  -1.120  -1.120  -1.043  -1.090  -1.139  -1.072  -1.086  -1.055
219   I        -1.439  -1.436  -1.474  -1.303  -1.271  -1.414  -1.205  -1.203  -1.201
220   Q        -1.439  -1.366  -1.465  -1.157  -1.026  -1.257  -1.205  -1.131  -1.193
221   A        -0.073  -0.069   0.001  -0.473  -0.476  -0.347  -0.409  -0.403  -0.302
222   A        -0.073  -0.069   0.001  -0.473  -0.476  -0.347  -0.409  -0.403  -0.302
223   K        -0.268  -0.309  -0.566  -0.115  -0.162  -0.581  -0.276  -0.335  -0.683
224   T        -1.226  -1.218  -1.126  -0.923  -0.910  -0.788  -1.205  -1.192  -1.062
225   I        -0.756  -0.745  -0.664  -0.774  -0.767  -0.644  -0.940  -0.925  -0.813
226   V        -0.073  -0.069   0.001  -0.149  -0.145  -0.049  -0.409  -0.403  -0.302
227   K        -0.543  -0.515  -0.608  -0.488  -0.442  -0.586  -0.674  -0.632  -0.744
228   E        -0.073  -0.081  -0.003  -0.146  -0.152  -0.022  -0.409  -0.426  -0.309
229   G         0.397   0.397   0.127   0.349   0.348   0.001   0.387   0.386  -0.073
230   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
231   I        -1.226  -1.220  -1.128  -1.338  -1.328  -1.167  -1.205  -1.195  -1.065
232   A        -1.097  -1.096  -1.111  -0.938  -0.933  -0.989  -1.072  -1.066  -1.048
233   S         1.104   1.111   1.144   1.050   1.063   1.117   1.183   1.192   1.240
234   L        -0.756  -0.745  -0.664  -0.964  -0.954  -0.819  -0.940  -0.925  -0.813
235   F         1.104   1.111   1.144   1.169   1.182   1.228   1.183   1.192   1.240
236   K        -0.268  -0.350  -0.566  -0.036  -0.139  -0.425  -0.276  -0.387  -0.683
237   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
238   S         1.104   1.111   1.144   1.050   1.063   1.117   1.183   1.192   1.240
239   L        -0.756  -0.749  -0.671  -1.108  -1.096  -0.977  -0.940  -0.929  -0.822
240   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
241   T         1.104   1.111   1.144   1.137   1.150   1.198   1.183   1.192   1.240
242   L         1.104   1.111   1.144   1.076   1.089   1.141   1.183   1.192   1.240
243   A         0.397   0.397   0.127   0.280   0.271  -0.124   0.387   0.386  -0.073
244   R         1.104   1.111   1.144   1.315   1.324   1.365   1.183   1.192   1.240
245   D         1.104   1.111   1.144   1.306   1.318   1.356   1.183   1.192   1.240
246   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
247   P         1.104   1.111   1.144   1.240   1.251   1.295   1.183   1.192   1.240
248   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
249   S         1.104   1.111   1.144   1.050   1.063   1.117   1.183   1.192   1.240
250   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
251   L         0.397   0.298   0.114   0.407   0.264  -0.064   0.387   0.233  -0.096
252   Y         1.104   1.111   1.144   1.341   1.352   1.390   1.183   1.192   1.240
253   F         1.104   1.111   1.144   1.169   1.182   1.228   1.183   1.192   1.240
254   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
255   S        -0.627  -0.682  -0.643  -0.836  -0.921  -0.864  -0.807  -0.860  -0.789
256   Y         1.104   1.111   1.144   1.341   1.352   1.390   1.183   1.192   1.240
257   E         1.104   1.111   1.144   1.319   1.329   1.369   1.183   1.192   1.240
258   I        -1.097  -1.082  -1.115  -0.888  -0.862  -0.945  -1.072  -1.055  -1.051
259   S        -1.567  -1.582  -1.502  -1.420  -1.431  -1.252  -1.338  -1.346  -1.226
260   K         1.104   1.111   1.144   1.146   1.158   1.207   1.183   1.192   1.240
261   N        -1.567  -1.564  -1.496  -1.323  -1.321  -1.217  -1.338  -1.330  -1.221
262   Y        -1.909  -1.891  -1.808  -1.533  -1.542  -1.421  -1.470  -1.454  -1.334
263   L         1.104   1.111   1.144   1.076   1.089   1.141   1.183   1.192   1.240
264   N        -0.756  -0.748  -0.671  -0.785  -0.764  -0.683  -0.940  -0.929  -0.822
265   S        -1.226  -1.199  -1.133  -1.268  -1.216  -1.116  -1.205  -1.179  -1.069
266   R        -1.439  -1.498  -1.492  -1.219  -1.320  -1.361  -1.205  -1.261  -1.217
267   Q        -1.285  -1.280  -1.149  -1.353  -1.334  -1.140  -1.255  -1.246  -1.083
268   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   D        -1.670  -1.660  -1.518  -1.675  -1.647  -1.442  -1.417  -1.405  -1.238
272   A        -0.534  -0.472  -0.607  -0.756  -0.659  -0.896  -0.637  -0.551  -0.738
273   G        -1.670  -1.660  -1.518  -1.557  -1.525  -1.331  -1.417  -1.405  -1.238
274   K        -1.192  -1.135  -1.130  -1.323  -1.256  -1.179  -1.157  -1.091  -1.065
275   D        -1.567  -1.528  -1.484  -1.582  -1.524  -1.483  -1.338  -1.302  -1.212
276   E        -1.567  -1.530  -1.484  -1.392  -1.363  -1.249  -1.338  -1.303  -1.212
277   P        -1.226  -1.256  -1.131  -1.014  -1.053  -0.883  -1.205  -1.225  -1.067
278   V         0.073   0.079   0.046  -0.082  -0.072  -0.154  -0.144  -0.135  -0.220
279   N         0.073   0.079   0.046   0.009   0.022  -0.022  -0.144  -0.135  -0.220
280   I         0.073   0.072   0.039  -0.022  -0.021  -0.084  -0.144  -0.148  -0.231
281   L        -1.567  -1.603  -1.497  -1.724  -1.803  -1.627  -1.338  -1.362  -1.222
282   N        -0.073  -0.069   0.001  -0.302  -0.301  -0.158  -0.409  -0.403  -0.302
283   V        -0.073  -0.069   0.001  -0.272  -0.265  -0.159  -0.409  -0.403  -0.302
284   C        -1.097  -1.063  -1.115  -0.816  -0.779  -0.875  -1.072  -1.041  -1.051
285   L        -1.909  -1.897  -1.812  -1.735  -1.732  -1.574  -1.470  -1.459  -1.336
286   A         0.397   0.397   0.127   0.280   0.271  -0.124   0.387   0.386  -0.073
287   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
288   G         0.397   0.298   0.114   0.284   0.136  -0.175   0.387   0.233  -0.096
289   I        -1.567  -1.558  -1.496  -1.287  -1.299  -1.186  -1.338  -1.329  -1.221
290   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
291   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
292   M         0.073   0.079   0.046   0.001   0.009  -0.026  -0.144  -0.135  -0.220
293   S         0.073   0.032   0.022  -0.149  -0.233  -0.285  -0.144  -0.218  -0.263
294   M         1.104   1.111   1.144   1.343   1.356   1.392   1.183   1.192   1.240
295   W         1.104   1.111   1.144   1.423   1.434   1.466   1.183   1.192   1.240
296   L        -0.543  -0.614  -0.628  -0.648  -0.742  -0.771  -0.674  -0.756  -0.770
297   A        -1.226  -1.219  -1.136  -1.462  -1.432  -1.312  -1.205  -1.194  -1.072
298   V         1.104   1.111   1.144   1.038   1.045   1.105   1.183   1.192   1.240
299   F         1.104   1.111   1.144   1.169   1.182   1.228   1.183   1.192   1.240
300   P         1.104   1.111   1.144   1.240   1.251   1.295   1.183   1.192   1.240
301   I         1.104   1.111   1.144   1.195   1.209   1.252   1.183   1.192   1.240
302   D         1.104   1.111   1.144   1.306   1.318   1.356   1.183   1.192   1.240
303   T         1.104   1.111   1.144   1.137   1.150   1.198   1.183   1.192   1.240
304   I         0.073   0.023   0.013   0.032  -0.064  -0.128  -0.144  -0.235  -0.280
305   K         1.104   1.111   1.144   1.146   1.158   1.207   1.183   1.192   1.240
306   T        -0.073  -0.069   0.001  -0.332  -0.321  -0.203  -0.409  -0.403  -0.302
307   K        -1.567  -1.557  -1.491  -1.363  -1.328  -1.242  -1.338  -1.323  -1.217
308   L         0.073   0.135   0.067   0.020   0.117   0.015  -0.144  -0.036  -0.180
309   Q         1.104   1.111   1.144   1.301   1.310   1.352   1.183   1.192   1.240
310   A        -0.885  -0.958  -1.079  -0.884  -0.998  -1.235  -0.807  -0.893  -1.011
311   S         0.073   0.029   0.014  -0.149  -0.240  -0.305  -0.144  -0.224  -0.278
312   S        -1.226  -1.213  -1.136  -1.106  -1.084  -0.976  -1.205  -1.189  -1.071
313   T        -0.885  -0.923  -1.072  -0.788  -0.858  -1.136  -0.807  -0.854  -1.003
314   R        -0.756  -0.767  -0.664  -0.628  -0.640  -0.489  -0.940  -0.953  -0.813
315   Q        -0.627  -0.683  -0.630  -0.585  -0.659  -0.588  -0.807  -0.860  -0.774
316   N        -0.268  -0.363  -0.568  -0.166  -0.292  -0.573  -0.276  -0.404  -0.686
317   M        -0.073  -0.069   0.001  -0.085  -0.074   0.034  -0.409  -0.403  -0.302
318   L        -1.097  -1.132  -1.105  -1.271  -1.329  -1.299  -1.072  -1.101  -1.042
319   S        -1.439  -1.473  -1.469  -1.155  -1.232  -1.262  -1.205  -1.238  -1.197
320   A        -0.756  -0.723  -0.648  -1.084  -1.034  -0.905  -0.940  -0.895  -0.792
321   T         0.397   0.298   0.114   0.486   0.350   0.033   0.387   0.233  -0.096
322   K        -0.268  -0.223  -0.551  -0.043   0.017  -0.417  -0.276  -0.216  -0.663
323   E        -1.909  -1.936  -1.816  -1.388  -1.417  -1.272  -1.470  -1.487  -1.339
324   I         0.397   0.298   0.114   0.550   0.417   0.100   0.387   0.233  -0.096
325   Y         1.104   1.111   1.144   1.341   1.352   1.390   1.183   1.192   1.240
326   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   Q        -1.567  -1.582  -1.502  -1.469  -1.468  -1.348  -1.338  -1.346  -1.226
328   R        -0.543  -0.576  -0.611  -0.438  -0.484  -0.598  -0.674  -0.700  -0.745
329   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
330   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
331   I         0.397   0.298   0.114   0.594   0.474   0.205   0.387   0.233  -0.096
332   K         1.104   1.111   1.144   1.146   1.158   1.207   1.183   1.192   1.240
333   G        -0.073  -0.069   0.001  -0.552  -0.556  -0.415  -0.409  -0.403  -0.302
334   F         1.104   1.111   1.144   1.169   1.182   1.228   1.183   1.192   1.240
335   F         1.104   1.111   1.144   1.169   1.182   1.228   1.183   1.192   1.240
336   P         1.104   1.111   1.144   1.240   1.251   1.295   1.183   1.192   1.240
337   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
338   L        -1.097  -1.144  -1.114  -1.175  -1.238  -1.159  -1.072  -1.117  -1.049
339   G         0.397   0.298   0.114   0.284   0.136  -0.175   0.387   0.233  -0.096
340   P         1.104   1.111   1.144   1.240   1.251   1.295   1.183   1.192   1.240
341   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
342   L         0.397   0.397   0.127   0.452   0.455   0.065   0.387   0.386  -0.073
343   L        -0.073  -0.069   0.001  -0.472  -0.472  -0.332  -0.409  -0.403  -0.302
344   R         1.104   1.111   1.144   1.315   1.324   1.365   1.183   1.192   1.240
345   S         0.397   0.298   0.114   0.381   0.239  -0.088   0.387   0.233  -0.096
346   F         0.397   0.298   0.114   0.519   0.382   0.062   0.387   0.233  -0.096
347   P         1.104   1.111   1.144   1.240   1.251   1.295   1.183   1.192   1.240
348   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
349   N         1.104   1.111   1.144   1.335   1.347   1.383   1.183   1.192   1.240
350   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
351   A         1.104   1.111   1.144   0.930   0.931   1.004   1.183   1.192   1.240
352   T         1.104   1.111   1.144   1.137   1.150   1.198   1.183   1.192   1.240
353   F         1.104   1.111   1.144   1.169   1.182   1.228   1.183   1.192   1.240
354   L         0.397   0.419   0.128   0.425   0.457   0.005   0.387   0.419  -0.071
355   G         1.104   1.111   1.144   0.955   0.962   1.027   1.183   1.192   1.240
356   V         1.104   1.111   1.144   1.038   1.045   1.105   1.183   1.192   1.240
357   E         1.104   1.111   1.144   1.319   1.329   1.369   1.183   1.192   1.240
358   M         0.397   0.396   0.128   0.477   0.481   0.126   0.387   0.385  -0.071
359   T        -0.073  -0.069   0.001  -0.432  -0.431  -0.291  -0.409  -0.403  -0.302
360   H         0.073   0.135   0.067   0.337   0.438   0.298  -0.144  -0.036  -0.180
361   S        -1.567  -1.576  -1.500  -1.506  -1.510  -1.374  -1.338  -1.342  -1.224
362   L        -0.756  -0.766  -0.663  -1.009  -1.041  -0.874  -0.940  -0.952  -0.812
363   F        -0.268  -0.309  -0.566  -0.059  -0.103  -0.495  -0.276  -0.335  -0.683
364   K        -1.097  -1.120  -1.120  -0.925  -0.939  -0.930  -1.072  -1.086  -1.055
365   K         0.073   0.115   0.042  -0.010   0.068  -0.097  -0.144  -0.071  -0.227
366   Y        -1.567  -1.580  -1.502  -1.447  -1.482  -1.371  -1.338  -1.345  -1.226
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   G        -1.285  -1.252  -1.149  -1.364  -1.281  -1.150  -1.255  -1.217  -1.083
374   I        -1.439  -1.451  -1.474  -1.252  -1.253  -1.345  -1.205  -1.217  -1.202
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12289
Output conservation file - output/Q12289
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
