1     M         1.938   1.939   2.044   2.175   2.177   2.349   2.168   2.170   2.341
2     T        -0.569  -0.572  -0.523  -0.621  -0.627  -0.545  -0.669  -0.671  -0.594
3     V         0.669   0.655   0.745   0.389   0.356   0.496   0.283   0.254   0.371
4     -        -0.676  -0.673  -0.579  -0.748  -0.744  -0.603  -0.778  -0.775  -0.653
5     -        -0.676  -0.673  -0.579  -0.969  -0.975  -0.826  -0.778  -0.775  -0.653
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    K        -1.005  -1.012  -0.949  -0.848  -0.856  -0.776  -0.887  -0.894  -0.804
17    K        -0.097  -0.094  -0.011  -0.125  -0.119   0.000  -0.397  -0.393  -0.286
18    I        -0.097  -0.096  -0.007  -0.479  -0.478  -0.353  -0.397  -0.396  -0.281
19    A         1.938   1.939   2.044   2.020   2.022   2.192   2.168   2.170   2.341
20    I         1.165   1.160   1.029   1.206   1.201   1.006   1.206   1.199   0.936
21    L         1.165   1.153   1.025   1.077   1.063   0.891   1.206   1.187   0.929
22    Y        -0.611  -0.612  -0.550  -0.738  -0.740  -0.638  -0.718  -0.718  -0.625
23    T        -0.470  -0.472  -0.476  -0.447  -0.450  -0.450  -0.557  -0.559  -0.542
24    D         1.165   1.169   1.030   1.286   1.295   1.106   1.206   1.212   0.939
25    E        -0.238  -0.242  -0.383  -0.068  -0.076  -0.298  -0.237  -0.243  -0.418
26    D         0.436   0.442   0.254   0.699   0.708   0.438   0.405   0.413   0.118
27    N        -0.611  -0.612  -0.550  -0.709  -0.710  -0.595  -0.718  -0.718  -0.625
28    -         0.146   0.142   0.106   0.179   0.172   0.078  -0.032  -0.039  -0.110
29    E        -0.470  -0.458  -0.470  -0.596  -0.584  -0.589  -0.557  -0.545  -0.538
30    W        -0.611  -0.609  -0.544  -0.598  -0.596  -0.510  -0.718  -0.715  -0.618
31    S        -0.470  -0.461  -0.479  -0.430  -0.420  -0.424  -0.557  -0.548  -0.544
32    K        -0.984  -0.987  -0.955  -0.973  -0.976  -0.912  -0.878  -0.880  -0.813
33    P        -1.358  -1.356  -1.316  -1.137  -1.130  -1.064  -1.038  -1.036  -0.962
34    W        -0.843  -0.850  -0.907  -0.477  -0.488  -0.567  -0.718  -0.725  -0.762
35    G         1.165   1.166   1.029   1.164   1.165   0.977   1.206   1.209   0.936
36    N        -0.843  -0.838  -0.889  -0.715  -0.705  -0.805  -0.718  -0.712  -0.744
37    F         0.650   0.653   0.746   0.527   0.533   0.674   0.244   0.250   0.374
38    V        -0.470  -0.471  -0.475  -0.548  -0.552  -0.545  -0.557  -0.560  -0.543
39    D         0.436   0.427   0.249   0.568   0.557   0.275   0.405   0.390   0.110
40    M        -0.470  -0.459  -0.474  -0.338  -0.322  -0.360  -0.557  -0.545  -0.538
41    A        -0.611  -0.609  -0.544  -0.740  -0.738  -0.644  -0.718  -0.715  -0.618
42    I        -0.984  -0.979  -0.934  -1.024  -1.018  -0.939  -0.878  -0.872  -0.795
43    K        -1.358  -1.356  -1.316  -1.200  -1.196  -1.142  -1.038  -1.036  -0.962
44    L         1.938   1.939   2.044   1.779   1.781   1.949   2.168   2.170   2.341
45    L         1.165   1.166   1.029   1.077   1.080   0.897   1.206   1.209   0.936
46    E        -0.470  -0.469  -0.473  -0.524  -0.526  -0.515  -0.557  -0.557  -0.541
47    Q        -0.470  -0.478  -0.474  -0.354  -0.368  -0.357  -0.557  -0.566  -0.538
48    T         0.136   0.143   0.115   0.081   0.093   0.041  -0.076  -0.065  -0.107
49    R        -1.358  -1.361  -1.299  -1.344  -1.350  -1.259  -1.038  -1.041  -0.949
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    K        -1.005  -0.997  -0.946  -0.966  -0.952  -0.873  -0.887  -0.879  -0.801
80    L        -1.005  -0.994  -0.946  -0.909  -0.890  -0.826  -0.887  -0.876  -0.801
81    E         0.031   0.015   0.051   0.009  -0.009   0.047  -0.232  -0.250  -0.202
82    C         0.302   0.299   0.193   0.536   0.527   0.373   0.204   0.199   0.023
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    I        -1.097  -1.095  -1.001  -1.267  -1.261  -1.127  -0.974  -0.972  -0.852
87    A        -0.574  -0.554  -0.517  -0.687  -0.661  -0.601  -0.660  -0.636  -0.582
88    E        -0.574  -0.591  -0.540  -0.619  -0.650  -0.581  -0.660  -0.679  -0.609
89    D        -0.574  -0.585  -0.523  -0.578  -0.597  -0.508  -0.660  -0.672  -0.590
90    V        -0.051  -0.062   0.011  -0.440  -0.456  -0.343  -0.346  -0.359  -0.260
91    E         0.146   0.148   0.102  -0.019  -0.020  -0.116  -0.032  -0.029  -0.115
92    Y        -0.470  -0.474  -0.480  -0.272  -0.280  -0.295  -0.557  -0.562  -0.545
93    E        -1.358  -1.364  -1.315  -1.293  -1.302  -1.245  -1.038  -1.043  -0.962
94    V        -0.984  -0.979  -0.957  -0.987  -0.979  -0.925  -0.878  -0.873  -0.815
95    F         0.136   0.133   0.098   0.247   0.242   0.197  -0.076  -0.081  -0.132
96    H        -0.470  -0.471  -0.474  -0.443  -0.443  -0.441  -0.557  -0.558  -0.539
97    V         1.165   1.169   1.030   1.131   1.135   0.921   1.206   1.212   0.939
98    Q        -0.984  -0.984  -0.942  -0.843  -0.841  -0.753  -0.878  -0.877  -0.801
99    K        -0.470  -0.473  -0.471  -0.467  -0.468  -0.461  -0.557  -0.562  -0.538
100   N         0.044   0.038   0.066  -0.070  -0.078  -0.032  -0.237  -0.244  -0.192
101   -        -0.676  -0.675  -0.579  -0.864  -0.865  -0.721  -0.778  -0.777  -0.653
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.097  -1.096  -1.001  -1.016  -1.015  -0.874  -0.974  -0.973  -0.852
114   V        -0.470  -0.476  -0.489  -0.561  -0.569  -0.606  -0.557  -0.563  -0.558
115   F         0.436   0.428   0.232   0.665   0.652   0.332   0.405   0.392   0.084
116   P         0.436   0.435   0.238   0.664   0.662   0.355   0.405   0.403   0.093
117   Q        -0.470  -0.465  -0.459  -0.397  -0.393  -0.367  -0.557  -0.553  -0.524
118   L        -0.238  -0.237  -0.367  -0.332  -0.331  -0.548  -0.237  -0.236  -0.397
119   S        -0.984  -0.989  -0.935  -0.960  -0.968  -0.886  -0.878  -0.881  -0.796
120   D         0.436   0.429   0.251   0.593   0.584   0.318   0.405   0.393   0.112
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   L         0.878   0.870   0.862   0.682   0.666   0.665   0.695   0.680   0.611
123   Q        -0.023  -0.021   0.029  -0.058  -0.056   0.019  -0.287  -0.284  -0.226
124   K        -1.097  -1.091  -1.001  -1.145  -1.131  -1.004  -0.974  -0.969  -0.852
125   D        -0.574  -0.586  -0.520  -0.645  -0.659  -0.565  -0.660  -0.675  -0.586
126   E        -1.097  -1.091  -1.001  -1.248  -1.234  -1.108  -0.974  -0.969  -0.852
127   Y        -0.097  -0.096  -0.011  -0.309  -0.307  -0.190  -0.397  -0.395  -0.286
128   L        -0.984  -0.986  -0.957  -1.049  -1.053  -0.988  -0.878  -0.879  -0.815
129   G         0.650   0.653   0.746   0.360   0.364   0.506   0.244   0.250   0.374
130   I        -0.238  -0.248  -0.384  -0.200  -0.218  -0.464  -0.237  -0.250  -0.419
131   Y        -0.611  -0.609  -0.544  -0.817  -0.813  -0.720  -0.718  -0.715  -0.618
132   I         0.436   0.435   0.238   0.470   0.468   0.135   0.405   0.403   0.093
133   T         0.810   0.810   0.826   0.734   0.732   0.733   0.565   0.564   0.539
134   G         1.938   1.939   2.044   1.872   1.874   2.043   2.168   2.170   2.341
135   S         1.938   1.939   2.044   1.976   1.978   2.148   2.168   2.170   2.341
136   K         0.810   0.802   0.808   0.746   0.738   0.727   0.565   0.549   0.502
137   Y        -0.984  -0.979  -0.957  -0.804  -0.797  -0.751  -0.878  -0.873  -0.815
138   D         0.810   0.809   0.824   0.734   0.735   0.729   0.565   0.563   0.535
139   S         0.650   0.649   0.739   0.454   0.449   0.582   0.244   0.241   0.359
140   F        -0.238  -0.227  -0.384   0.011   0.027  -0.198  -0.237  -0.223  -0.419
141   D         0.878   0.870   0.862   0.890   0.876   0.849   0.695   0.680   0.611
142   N        -0.984  -0.990  -0.944  -0.908  -0.918  -0.842  -0.878  -0.882  -0.803
143   E        -0.470  -0.464  -0.476  -0.543  -0.534  -0.539  -0.557  -0.550  -0.541
144   I        -1.731  -1.731  -1.637  -1.716  -1.709  -1.580  -1.199  -1.197  -1.080
145   E        -0.238  -0.242  -0.383  -0.054  -0.062  -0.322  -0.237  -0.243  -0.418
146   W         1.938   1.939   2.044   2.219   2.222   2.394   2.168   2.170   2.341
147   I         1.938   1.939   2.044   1.933   1.935   2.104   2.168   2.170   2.341
148   M        -1.358  -1.353  -1.297  -1.341  -1.332  -1.254  -1.038  -1.033  -0.947
149   K         1.165   1.153   1.025   1.244   1.236   1.053   1.206   1.187   0.929
150   L         1.938   1.939   2.044   1.779   1.781   1.949   2.168   2.170   2.341
151   R        -0.611  -0.612  -0.550  -0.639  -0.639  -0.548  -0.718  -0.718  -0.625
152   S         0.136   0.126   0.094  -0.001  -0.015  -0.073  -0.076  -0.089  -0.143
153   F         1.165   1.153   1.025   1.275   1.262   1.057   1.206   1.187   0.929
154   L        -0.470  -0.458  -0.475  -0.730  -0.716  -0.731  -0.557  -0.544  -0.541
155   N        -0.238  -0.242  -0.383  -0.100  -0.101  -0.325  -0.237  -0.243  -0.418
156   E        -1.358  -1.356  -1.301  -1.104  -1.099  -1.015  -1.038  -1.037  -0.950
157   M        -0.843  -0.837  -0.875  -0.791  -0.785  -0.842  -0.718  -0.710  -0.730
158   L         0.436   0.421   0.251   0.365   0.343   0.085   0.405   0.382   0.112
159   T        -0.470  -0.467  -0.460  -0.441  -0.436  -0.419  -0.557  -0.554  -0.525
160   S        -0.984  -0.978  -0.934  -1.055  -1.047  -0.977  -0.878  -0.872  -0.794
161   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   T        -0.676  -0.674  -0.579  -0.755  -0.754  -0.610  -0.778  -0.775  -0.653
185   E        -0.569  -0.591  -0.516  -0.673  -0.702  -0.585  -0.669  -0.690  -0.587
186   Y        -1.358  -1.365  -1.300  -1.121  -1.127  -1.028  -1.038  -1.043  -0.950
187   P        -0.984  -0.978  -0.941  -1.086  -1.076  -1.008  -0.878  -0.872  -0.801
188   P         0.650   0.653   0.746   0.487   0.496   0.630   0.244   0.250   0.374
189   V         0.650   0.651   0.739   0.317   0.317   0.441   0.244   0.245   0.358
190   A         0.136   0.145   0.113  -0.020  -0.005  -0.051  -0.076  -0.061  -0.110
191   G         1.938   1.939   2.044   1.872   1.874   2.043   2.168   2.170   2.341
192   I         0.436   0.434   0.253   0.470   0.466   0.160   0.405   0.401   0.115
193   C         1.938   1.939   2.044   2.205   2.207   2.379   2.168   2.170   2.341
194   F         1.938   1.939   2.044   2.017   2.021   2.189   2.168   2.170   2.341
195   G         1.938   1.939   2.044   1.872   1.874   2.043   2.168   2.170   2.341
196   H         1.938   1.939   2.044   2.124   2.125   2.297   2.168   2.170   2.341
197   Q         1.938   1.939   2.044   2.017   2.018   2.189   2.168   2.170   2.341
198   V         0.136   0.129   0.100   0.045   0.032   0.004  -0.076  -0.087  -0.128
199   I         0.044   0.042   0.076  -0.298  -0.301  -0.244  -0.237  -0.238  -0.180
200   A         1.165   1.166   1.029   1.293   1.296   1.092   1.206   1.209   0.936
201   A         0.044   0.047   0.064  -0.014  -0.007   0.035  -0.237  -0.234  -0.195
202   A        -0.238  -0.248  -0.384  -0.086  -0.104  -0.341  -0.237  -0.250  -0.419
203   L         1.165   1.161   1.030   1.078   1.073   0.900   1.206   1.200   0.939
204   G         1.938   1.939   2.044   1.872   1.874   2.043   2.168   2.170   2.341
205   S        -0.984  -0.987  -0.955  -0.848  -0.852  -0.802  -0.878  -0.880  -0.813
206   S        -1.358  -1.356  -1.316  -1.223  -1.217  -1.160  -1.038  -1.036  -0.962
207   V         0.136   0.149   0.109  -0.055  -0.037  -0.112  -0.076  -0.060  -0.120
208   G         0.136   0.140   0.100  -0.061  -0.054  -0.128  -0.076  -0.068  -0.130
209   R         1.165   1.161   1.030   1.396   1.392   1.214   1.206   1.200   0.939
210   N         1.938   1.939   2.044   2.032   2.033   2.204   2.168   2.170   2.341
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   P         0.650   0.651   0.741   0.449   0.448   0.576   0.244   0.245   0.363
214   K         0.436   0.435   0.238   0.521   0.526   0.206   0.405   0.403   0.093
215   G         1.938   1.939   2.044   1.872   1.874   2.043   2.168   2.170   2.341
216   F         0.436   0.428   0.232   0.783   0.770   0.445   0.405   0.392   0.084
217   E         1.938   1.939   2.044   1.888   1.889   2.059   2.168   2.170   2.341
218   G        -0.470  -0.473  -0.489  -0.518  -0.523  -0.523  -0.557  -0.561  -0.558
219   G         0.136   0.148   0.096   0.001   0.015  -0.057  -0.076  -0.061  -0.137
220   V        -0.097  -0.094  -0.011  -0.361  -0.358  -0.234  -0.397  -0.393  -0.287
221   V         0.136   0.135   0.093   0.141   0.137   0.068  -0.076  -0.079  -0.144
222   S        -1.358  -1.356  -1.316  -1.306  -1.307  -1.262  -1.038  -1.036  -0.962
223   L         0.044   0.047   0.068  -0.251  -0.250  -0.220  -0.237  -0.234  -0.190
224   K        -0.843  -0.842  -0.879  -0.727  -0.725  -0.813  -0.718  -0.716  -0.734
225   L         1.938   1.939   2.044   1.779   1.781   1.949   2.168   2.170   2.341
226   N         0.650   0.653   0.746   0.471   0.475   0.616   0.244   0.250   0.374
227   S        -1.358  -1.362  -1.314  -1.266  -1.273  -1.195  -1.038  -1.041  -0.961
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   V        -0.470  -0.480  -0.478  -0.585  -0.601  -0.582  -0.557  -0.568  -0.543
233   G         0.436   0.435   0.238   0.448   0.446   0.138   0.405   0.403   0.093
234   Q        -1.358  -1.359  -1.299  -1.204  -1.201  -1.116  -1.038  -1.039  -0.949
235   K        -0.470  -0.474  -0.472  -0.472  -0.475  -0.463  -0.557  -0.562  -0.539
236   L        -0.470  -0.462  -0.478  -0.616  -0.606  -0.620  -0.557  -0.549  -0.543
237   F         1.938   1.939   2.044   2.017   2.021   2.189   2.168   2.170   2.341
238   G        -0.984  -0.982  -0.943  -1.149  -1.151  -1.069  -0.878  -0.875  -0.803
239   A        -1.358  -1.350  -1.296  -1.119  -1.105  -1.037  -1.038  -1.031  -0.946
240   -        -0.676  -0.675  -0.579  -0.832  -0.829  -0.688  -0.778  -0.777  -0.653
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   Q        -0.843  -0.833  -0.888  -0.758  -0.737  -0.859  -0.718  -0.706  -0.743
268   E        -0.984  -0.984  -0.945  -0.909  -0.910  -0.855  -0.878  -0.877  -0.804
269   L         1.165   1.161   1.030   1.063   1.058   0.874   1.206   1.200   0.939
270   N        -0.238  -0.233  -0.366   0.011   0.018  -0.178  -0.237  -0.231  -0.396
271   L         0.044   0.042   0.057  -0.298  -0.303  -0.276  -0.237  -0.239  -0.202
272   S        -0.984  -0.979  -0.957  -0.931  -0.927  -0.862  -0.878  -0.873  -0.815
273   E         0.650   0.653   0.746   0.371   0.375   0.517   0.244   0.250   0.374
274   V        -0.843  -0.850  -0.907  -0.611  -0.625  -0.772  -0.718  -0.725  -0.762
275   H         1.938   1.939   2.044   2.124   2.125   2.297   2.168   2.170   2.341
276   S         0.136   0.133   0.098   0.150   0.143   0.099  -0.076  -0.081  -0.132
277   D         1.938   1.939   2.044   1.989   1.994   2.161   2.168   2.170   2.341
278   C        -0.470  -0.473  -0.475  -0.330  -0.334  -0.296  -0.557  -0.561  -0.543
279   V         0.436   0.436   0.258   0.470   0.469   0.207   0.405   0.404   0.124
280   F        -1.358  -1.356  -1.310  -1.193  -1.193  -1.106  -1.038  -1.036  -0.957
281   D        -0.470  -0.467  -0.473  -0.562  -0.559  -0.556  -0.557  -0.554  -0.541
282   V         0.810   0.810   0.826   0.547   0.545   0.530   0.565   0.564   0.539
283   P         1.938   1.939   2.044   2.078   2.080   2.251   2.168   2.170   2.341
284   E         0.136   0.132   0.093   0.055   0.047  -0.004  -0.076  -0.084  -0.145
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   G         0.436   0.435   0.238   0.484   0.482   0.198   0.405   0.403   0.093
295   Y        -0.984  -0.986  -0.957  -0.788  -0.790  -0.738  -0.878  -0.879  -0.815
296   Q        -0.470  -0.470  -0.469  -0.515  -0.516  -0.499  -0.557  -0.557  -0.536
297   N        -0.097  -0.099  -0.019  -0.410  -0.414  -0.288  -0.397  -0.400  -0.297
298   W        -0.097  -0.099  -0.019  -0.330  -0.333  -0.203  -0.397  -0.400  -0.297
299   A         0.810   0.812   0.810   0.640   0.643   0.619   0.565   0.569   0.506
300   S         1.165   1.153   1.025   1.292   1.277   1.117   1.206   1.187   0.929
301   S         0.650   0.653   0.741   0.428   0.433   0.561   0.244   0.250   0.362
302   E        -0.843  -0.834  -0.882  -0.775  -0.762  -0.837  -0.718  -0.707  -0.737
303   K         0.136   0.140   0.100   0.018   0.034  -0.047  -0.076  -0.068  -0.130
304   C         1.165   1.153   1.025   1.494   1.479   1.297   1.206   1.187   0.929
305   Q        -1.358  -1.356  -1.310  -1.223  -1.218  -1.141  -1.038  -1.036  -0.957
306   N        -0.984  -0.984  -0.945  -0.897  -0.893  -0.824  -0.878  -0.877  -0.804
307   Q         1.938   1.939   2.044   2.017   2.018   2.189   2.168   2.170   2.341
308   G         1.165   1.161   1.030   1.156   1.151   0.966   1.206   1.200   0.939
309   F         0.044   0.047   0.074  -0.157  -0.153  -0.085  -0.237  -0.234  -0.183
310   Y        -0.238  -0.238  -0.375   0.036   0.034  -0.188  -0.237  -0.237  -0.408
311   R        -0.470  -0.468  -0.472  -0.484  -0.477  -0.474  -0.557  -0.555  -0.536
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   Q         0.436   0.454   0.260   0.676   0.703   0.410   0.405   0.431   0.126
317   N        -1.731  -1.731  -1.637  -1.669  -1.670  -1.534  -1.199  -1.197  -1.080
318   R        -0.238  -0.232  -0.362   0.026   0.036  -0.179  -0.237  -0.229  -0.390
319   V        -0.843  -0.837  -0.888  -0.833  -0.825  -0.914  -0.718  -0.710  -0.742
320   L         1.165   1.182   1.033   1.063   1.086   0.878   1.206   1.235   0.944
321   T         1.165   1.182   1.033   1.279   1.302   1.098   1.206   1.235   0.944
322   F         0.436   0.453   0.253   0.555   0.582   0.244   0.405   0.429   0.116
323   Q         1.938   1.939   2.044   2.017   2.018   2.189   2.168   2.170   2.341
324   G         1.938   1.939   2.044   1.872   1.874   2.043   2.168   2.170   2.341
325   H         1.938   1.939   2.044   2.124   2.125   2.297   2.168   2.170   2.341
326   P         1.938   1.939   2.044   2.078   2.080   2.251   2.168   2.170   2.341
327   E         1.938   1.939   2.044   1.888   1.889   2.059   2.168   2.170   2.341
328   F         1.938   1.939   2.044   2.017   2.021   2.189   2.168   2.170   2.341
329   N        -0.470  -0.460  -0.456  -0.495  -0.483  -0.476  -0.557  -0.547  -0.521
330   S         0.436   0.454   0.260   0.606   0.629   0.353   0.405   0.431   0.126
331   D        -0.984  -0.981  -0.934  -1.035  -1.029  -0.960  -0.878  -0.874  -0.795
332   V        -0.470  -0.481  -0.471  -0.669  -0.689  -0.697  -0.557  -0.569  -0.538
333   A        -0.470  -0.464  -0.476  -0.481  -0.472  -0.480  -0.557  -0.550  -0.541
334   Q        -1.731  -1.731  -1.637  -1.687  -1.684  -1.551  -1.199  -1.197  -1.080
335   K        -0.470  -0.471  -0.473  -0.555  -0.553  -0.562  -0.557  -0.559  -0.540
336   G        -1.358  -1.365  -1.300  -1.296  -1.306  -1.216  -1.038  -1.043  -0.950
337   L         0.436   0.422   0.253   0.359   0.337   0.079   0.405   0.384   0.116
338   L        -0.843  -0.838  -0.889  -0.809  -0.795  -0.913  -0.718  -0.712  -0.744
339   K        -0.984  -0.987  -0.945  -1.046  -1.045  -0.977  -0.878  -0.880  -0.804
340   S        -0.984  -0.992  -0.944  -0.933  -0.945  -0.887  -0.878  -0.884  -0.803
341   Q        -1.731  -1.731  -1.637  -1.404  -1.398  -1.266  -1.199  -1.197  -1.080
342   D        -0.611  -0.609  -0.543  -0.804  -0.804  -0.691  -0.718  -0.716  -0.618
343   -        -0.405  -0.384  -0.438  -0.247  -0.219  -0.286  -0.450  -0.424  -0.486
344   -         1.088   1.105   0.986   1.043   1.064   0.882   1.077   1.105   0.856
345   K        -0.470  -0.476  -0.475  -0.688  -0.698  -0.700  -0.557  -0.564  -0.543
346   L         0.650   0.649   0.739   0.331   0.327   0.449   0.244   0.241   0.359
347   T        -0.470  -0.479  -0.471  -0.448  -0.462  -0.447  -0.557  -0.567  -0.538
348   L        -0.470  -0.470  -0.467  -0.622  -0.620  -0.628  -0.557  -0.557  -0.534
349   E         0.136   0.132   0.093   0.018   0.012  -0.051  -0.076  -0.082  -0.144
350   E        -0.097  -0.094  -0.017  -0.436  -0.435  -0.333  -0.397  -0.393  -0.295
351   F        -0.470  -0.464  -0.460  -0.344  -0.335  -0.315  -0.557  -0.551  -0.525
352   N        -0.843  -0.838  -0.889  -0.805  -0.797  -0.886  -0.718  -0.712  -0.744
353   R        -0.470  -0.468  -0.472  -0.545  -0.540  -0.529  -0.557  -0.555  -0.536
354   Y        -0.843  -0.856  -0.867  -0.551  -0.572  -0.598  -0.718  -0.731  -0.721
355   E        -1.731  -1.731  -1.637  -1.573  -1.575  -1.437  -1.199  -1.197  -1.080
356   R        -0.984  -0.987  -0.955  -0.870  -0.871  -0.823  -0.878  -0.880  -0.813
357   Q        -0.470  -0.461  -0.464  -0.406  -0.391  -0.411  -0.557  -0.547  -0.530
358   C        -0.984  -0.979  -0.957  -0.770  -0.764  -0.731  -0.878  -0.873  -0.815
359   Q        -1.358  -1.362  -1.314  -1.223  -1.227  -1.147  -1.038  -1.041  -0.961
360   E        -1.358  -1.353  -1.300  -1.321  -1.313  -1.250  -1.038  -1.034  -0.950
361   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   D        -0.405  -0.419  -0.455  -0.248  -0.269  -0.327  -0.450  -0.469  -0.507
363   N        -0.238  -0.227  -0.384  -0.019  -0.004  -0.249  -0.237  -0.223  -0.419
364   N         0.136   0.138   0.105   0.127   0.132   0.084  -0.076  -0.074  -0.123
365   G         1.165   1.161   1.030   1.173   1.168   0.996   1.206   1.200   0.939
366   I        -0.470  -0.474  -0.475  -0.540  -0.545  -0.557  -0.557  -0.562  -0.543
367   Q        -0.984  -0.981  -0.952  -0.986  -0.981  -0.911  -0.878  -0.875  -0.810
368   A        -0.097  -0.100  -0.013  -0.400  -0.408  -0.292  -0.397  -0.402  -0.290
369   A         0.810   0.810   0.826   0.724   0.723   0.713   0.565   0.564   0.539
370   R        -0.470  -0.472  -0.477  -0.421  -0.422  -0.439  -0.557  -0.559  -0.542
371   N        -0.470  -0.474  -0.480  -0.535  -0.543  -0.537  -0.557  -0.562  -0.545
372   I         0.436   0.453   0.253   0.499   0.524   0.208   0.405   0.429   0.116
373   W        -0.984  -0.984  -0.956  -0.844  -0.844  -0.803  -0.878  -0.877  -0.814
374   R        -0.238  -0.226  -0.352  -0.073  -0.050  -0.238  -0.237  -0.222  -0.378
375   L         0.810   0.806   0.826   0.687   0.680   0.666   0.565   0.556   0.539
376   F        -0.238  -0.249  -0.385  -0.256  -0.272  -0.467  -0.237  -0.251  -0.420
377   L        -0.238  -0.238  -0.354  -0.204  -0.205  -0.349  -0.237  -0.237  -0.381
378   Q        -1.358  -1.358  -1.301  -1.400  -1.405  -1.344  -1.038  -1.038  -0.950
379   K        -0.023  -0.068   0.006  -0.123  -0.199  -0.095  -0.287  -0.355  -0.260
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12288
Output conservation file - output/Q12288
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
