1     M         1.808   1.867   1.955   1.903   1.986   2.130   2.017   2.109   2.264
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     K        -1.062  -1.055  -1.010  -1.074  -1.052  -1.001  -0.956  -0.936  -0.857
5     Q        -0.328  -0.141  -0.431  -0.114   0.148  -0.276  -0.330  -0.077  -0.447
6     I         0.334   0.481   0.174   0.497   0.697   0.251   0.296   0.516   0.047
7     V        -0.659  -0.573  -0.574  -0.770  -0.644  -0.660  -0.743  -0.632  -0.624
8     K        -0.659  -0.683  -0.616  -0.763  -0.775  -0.692  -0.743  -0.765  -0.674
9     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    S        -0.117  -0.139  -0.077  -0.365  -0.429  -0.359  -0.379  -0.415  -0.334
14    H        -0.117  -0.139  -0.077  -0.068  -0.128  -0.030  -0.379  -0.415  -0.334
15    A        -0.759  -0.716  -0.642  -0.777  -0.694  -0.606  -0.858  -0.799  -0.702
16    I         0.767   0.858   0.764   0.725   0.861   0.691   0.580   0.732   0.509
17    R        -1.062  -1.024  -1.002  -0.962  -0.915  -0.881  -0.956  -0.901  -0.849
18    I        -1.062  -0.990  -0.997  -1.067  -0.959  -0.954  -0.956  -0.874  -0.845
19    V         0.038   0.066   0.003  -0.057  -0.068  -0.146  -0.173  -0.159  -0.229
20    A        -1.062  -1.086  -1.017  -1.105  -1.130  -1.042  -0.956  -0.960  -0.862
21    A        -0.051  -0.016  -0.003  -0.266  -0.199  -0.187  -0.330  -0.272  -0.241
22    L         1.049   1.084   0.917   0.978   1.035   0.820   1.078   1.131   0.811
23    G        -0.557  -0.463  -0.519  -0.682  -0.543  -0.616  -0.643  -0.514  -0.566
24    I        -0.557  -0.470  -0.522  -0.582  -0.444  -0.512  -0.643  -0.522  -0.570
25    I        -0.051  -0.125  -0.017  -0.185  -0.307  -0.137  -0.330  -0.404  -0.262
26    G         0.334   0.196   0.112   0.418   0.217   0.079   0.296   0.086  -0.048
27    L        -0.328  -0.412  -0.487  -0.285  -0.397  -0.497  -0.330  -0.437  -0.518
28    -        -0.065   0.002  -0.002  -0.174  -0.079  -0.095  -0.325  -0.228  -0.235
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    W        -0.065  -0.084  -0.046  -0.030  -0.099  -0.053  -0.325  -0.355  -0.297
32    M        -0.654  -0.658  -0.593  -0.441  -0.433  -0.329  -0.751  -0.746  -0.651
33    F        -0.493  -0.561  -0.559  -0.295  -0.422  -0.422  -0.538  -0.622  -0.605
34    F         0.974   1.043   0.886   1.156   1.257   1.042   0.952   1.063   0.751
35    S        -0.493  -0.541  -0.551  -0.422  -0.507  -0.500  -0.538  -0.600  -0.597
36    S        -0.065   0.021  -0.010  -0.211  -0.102  -0.123  -0.325  -0.205  -0.245
37    N        -1.082  -1.068  -1.020  -0.981  -0.974  -0.881  -0.964  -0.941  -0.863
38    -         0.525   0.570   0.662   0.299   0.371   0.512   0.100   0.167   0.297
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    E        -0.654  -0.594  -0.594  -0.858  -0.784  -0.757  -0.751  -0.675  -0.652
43    L        -1.082  -1.088  -1.038  -1.064  -1.074  -0.975  -0.964  -0.955  -0.879
44    S         0.974   1.037   0.863   0.969   1.058   0.810   0.952   1.052   0.705
45    I        -0.493  -0.502  -0.551  -0.391  -0.412  -0.504  -0.538  -0.543  -0.597
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    A        -1.062  -1.079  -1.010  -1.029  -1.043  -0.940  -0.956  -0.955  -0.856
77    T        -1.429  -1.405  -1.364  -1.335  -1.328  -1.242  -1.112  -1.077  -1.002
78    P         0.334   0.196   0.103   0.478   0.272   0.124   0.296   0.087  -0.061
79    G        -0.923  -0.901  -0.954  -0.719  -0.667  -0.756  -0.799  -0.770  -0.797
80    L        -0.557  -0.524  -0.558  -0.652  -0.603  -0.635  -0.643  -0.610  -0.614
81    I        -1.429  -1.437  -1.377  -1.314  -1.363  -1.246  -1.112  -1.103  -1.013
82    K        -1.429  -1.430  -1.369  -1.280  -1.247  -1.173  -1.112  -1.097  -1.007
83    A        -1.795  -1.760  -1.690  -1.520  -1.432  -1.364  -1.269  -1.222  -1.125
84    K        -1.062  -1.051  -1.019  -1.152  -1.127  -1.077  -0.956  -0.932  -0.864
85    S        -0.557  -0.456  -0.520  -0.642  -0.492  -0.563  -0.643  -0.507  -0.564
86    G        -1.429  -1.414  -1.366  -1.293  -1.276  -1.208  -1.112  -1.084  -1.004
87    I        -1.062  -1.075  -1.009  -1.169  -1.218  -1.100  -0.956  -0.952  -0.855
88    D        -0.328  -0.339  -0.468  -0.185  -0.223  -0.407  -0.330  -0.349  -0.494
89    -        -0.659  -0.571  -0.572  -0.756  -0.634  -0.631  -0.743  -0.626  -0.622
90    -        -1.172  -1.143  -1.060  -1.129  -1.087  -0.965  -1.050  -1.005  -0.899
91    -        -1.172  -1.143  -1.060  -1.263  -1.207  -1.102  -1.050  -1.005  -0.899
92    -        -0.145  -0.101  -0.053  -0.293  -0.233  -0.152  -0.436  -0.373  -0.307
93    -         0.049   0.004   0.011  -0.022  -0.122  -0.129  -0.130  -0.202  -0.203
94    E        -0.051  -0.017  -0.001  -0.244  -0.175  -0.133  -0.330  -0.272  -0.239
95    V        -1.429  -1.339  -1.351  -1.232  -1.076  -1.131  -1.112  -1.014  -0.992
96    Q        -0.923  -0.741  -0.931  -0.847  -0.559  -0.882  -0.799  -0.582  -0.773
97    G        -1.062  -1.086  -1.014  -1.015  -1.043  -0.929  -0.956  -0.960  -0.859
98    A        -1.062  -0.982  -1.007  -1.101  -0.984  -1.004  -0.956  -0.863  -0.853
99    A        -0.923  -0.889  -0.960  -0.885  -0.834  -0.937  -0.799  -0.759  -0.803
100   A        -0.923  -0.941  -0.967  -0.875  -0.906  -0.963  -0.799  -0.812  -0.811
101   E        -1.062  -0.967  -0.996  -1.147  -1.013  -1.049  -0.956  -0.855  -0.844
102   K        -1.082  -1.084  -1.026  -0.993  -1.009  -0.940  -0.964  -0.950  -0.869
103   N        -1.082  -1.029  -1.024  -0.986  -0.906  -0.915  -0.964  -0.895  -0.867
104   D         0.202   0.176   0.048   0.210   0.167  -0.085   0.100   0.063  -0.145
105   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   R        -0.659  -0.641  -0.589  -0.798  -0.778  -0.696  -0.743  -0.711  -0.642
107   L        -0.659  -0.621  -0.601  -0.688  -0.637  -0.619  -0.743  -0.687  -0.656
108   K        -0.659  -0.665  -0.619  -0.785  -0.793  -0.716  -0.743  -0.740  -0.676
109   E        -1.172  -1.155  -1.060  -1.337  -1.312  -1.177  -1.050  -1.017  -0.899
110   I        -0.659  -0.665  -0.619  -0.726  -0.744  -0.700  -0.743  -0.740  -0.676
111   E        -0.659  -0.646  -0.601  -0.908  -0.908  -0.846  -0.743  -0.719  -0.656
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   K        -0.659  -0.553  -0.599  -0.822  -0.651  -0.755  -0.743  -0.604  -0.654
135   Q        -0.659  -0.616  -0.594  -0.703  -0.645  -0.609  -0.743  -0.685  -0.648
136   T         0.562   0.571   0.660   0.313   0.298   0.432   0.177   0.169   0.294
137   I         0.334   0.247   0.113   0.517   0.391   0.227   0.296   0.157  -0.046
138   M         1.049   1.084   0.917   1.221   1.275   1.032   1.078   1.131   0.811
139   P         0.334   0.196   0.112   0.464   0.251   0.112   0.296   0.086  -0.048
140   L         0.038  -0.012   0.026  -0.210  -0.252  -0.233  -0.173  -0.223  -0.186
141   M         0.334   0.196   0.103   0.519   0.300   0.122   0.296   0.087  -0.061
142   G        -1.062  -1.063  -1.004  -1.048  -1.024  -0.948  -0.956  -0.942  -0.851
143   D         0.544   0.586   0.664   0.357   0.410   0.531   0.140   0.201   0.302
144   D        -1.429  -1.401  -1.369  -1.347  -1.295  -1.254  -1.112  -1.074  -1.007
145   K        -0.923  -0.889  -0.960  -0.783  -0.738  -0.855  -0.799  -0.759  -0.803
146   V        -0.557  -0.590  -0.561  -0.689  -0.736  -0.692  -0.643  -0.671  -0.615
147   K         1.049   0.910   0.889   0.981   0.809   0.772   1.078   0.828   0.756
148   K        -0.557  -0.562  -0.553  -0.659  -0.643  -0.632  -0.643  -0.636  -0.604
149   E        -0.328  -0.362  -0.472  -0.308  -0.387  -0.538  -0.330  -0.377  -0.499
150   V         0.334   0.263   0.121   0.333   0.239   0.050   0.296   0.179  -0.033
151   G         1.049   0.910   0.889   1.091   0.912   0.872   1.078   0.828   0.756
152   R         0.700   0.667   0.696   0.688   0.606   0.644   0.453   0.365   0.369
153   A         1.808   1.867   1.955   1.713   1.807   1.936   2.017   2.109   2.264
154   S         1.049   0.910   0.889   1.064   0.882   0.858   1.078   0.828   0.756
155   W         1.808   1.867   1.955   1.991   2.079   2.220   2.017   2.109   2.264
156   K         1.049   1.084   0.917   0.980   1.044   0.813   1.078   1.131   0.811
157   Y         0.544   0.626   0.694   0.246   0.366   0.463   0.140   0.282   0.364
158   F         1.049   0.910   0.889   1.234   1.047   1.010   1.078   0.828   0.756
159   H         1.808   1.867   1.955   1.910   1.996   2.137   2.017   2.109   2.264
160   T         1.808   1.867   1.955   1.776   1.860   2.000   2.017   2.109   2.264
161   L        -0.557  -0.634  -0.579  -0.629  -0.731  -0.622  -0.643  -0.715  -0.636
162   L         0.038  -0.073  -0.013  -0.083  -0.235  -0.138  -0.173  -0.319  -0.248
163   A         1.049   0.910   0.889   1.032   0.847   0.797   1.078   0.828   0.756
164   R         0.334   0.196   0.112   0.558   0.357   0.255   0.296   0.086  -0.048
165   F         0.544   0.565   0.657   0.469   0.489   0.628   0.140   0.156   0.287
166   P         1.808   1.867   1.955   1.816   1.897   2.041   2.017   2.109   2.264
167   D         0.038  -0.073  -0.013  -0.035  -0.202  -0.128  -0.173  -0.319  -0.248
168   E        -0.557  -0.593  -0.565  -0.665  -0.711  -0.673  -0.643  -0.678  -0.620
169   P         1.808   1.867   1.955   1.816   1.897   2.041   2.017   2.109   2.264
170   T         1.049   1.143   0.927   1.095   1.224   0.923   1.078   1.229   0.829
171   P        -1.429  -1.414  -1.360  -1.490  -1.484  -1.396  -1.112  -1.084  -0.999
172   E        -0.051  -0.124  -0.019  -0.171  -0.264  -0.106  -0.330  -0.403  -0.264
173   E         1.808   1.867   1.955   1.672   1.756   1.894   2.017   2.109   2.264
174   R        -0.328  -0.278  -0.457  -0.132  -0.059  -0.346  -0.330  -0.255  -0.480
175   E        -1.429  -1.404  -1.360  -1.285  -1.266  -1.189  -1.112  -1.077  -0.999
176   K        -0.557  -0.634  -0.579  -0.689  -0.786  -0.711  -0.643  -0.715  -0.636
177   L         1.808   1.867   1.955   1.626   1.714   1.848   2.017   2.109   2.264
178   H        -0.557  -0.492  -0.541  -0.624  -0.539  -0.581  -0.643  -0.573  -0.596
179   T        -0.557  -0.596  -0.560  -0.506  -0.557  -0.502  -0.643  -0.677  -0.615
180   F         0.544   0.626   0.694   0.465   0.600   0.694   0.140   0.282   0.364
181   I         0.544   0.572   0.660   0.225   0.243   0.374   0.140   0.170   0.294
182   G        -1.429  -1.404  -1.360  -1.092  -1.041  -0.990  -1.112  -1.077  -0.999
183   L         1.049   0.910   0.889   0.946   0.755   0.711   1.078   0.828   0.756
184   Y        -0.051  -0.122  -0.026  -0.032  -0.131   0.014  -0.330  -0.399  -0.271
185   A         1.049   1.083   0.928   1.032   1.094   0.863   1.078   1.130   0.832
186   E        -0.557  -0.634  -0.579  -0.555  -0.663  -0.555  -0.643  -0.715  -0.636
187   L         0.038  -0.054  -0.007  -0.136  -0.266  -0.200  -0.173  -0.289  -0.239
188   Y         1.049   0.910   0.889   1.230   1.055   1.025   1.078   0.828   0.756
189   P         1.808   1.867   1.955   1.816   1.897   2.041   2.017   2.109   2.264
190   C         1.808   1.867   1.955   1.921   2.013   2.148   2.017   2.109   2.264
191   G         1.808   1.867   1.955   1.757   1.850   1.981   2.017   2.109   2.264
192   E         0.700   0.760   0.729   0.493   0.581   0.507   0.453   0.547   0.438
193   C         1.049   0.910   0.889   1.266   1.093   1.056   1.078   0.828   0.756
194   S         0.544   0.571   0.661   0.213   0.242   0.373   0.140   0.168   0.296
195   Y        -0.923  -0.992  -0.998  -0.693  -0.821  -0.844  -0.799  -0.863  -0.842
196   H         1.049   0.910   0.889   1.222   1.023   0.977   1.078   0.828   0.756
197   F         1.049   0.910   0.889   1.207   1.008   0.955   1.078   0.828   0.756
198   V        -0.051   0.026  -0.009  -0.079   0.037   0.007  -0.330  -0.222  -0.248
199   K         1.808   1.867   1.955   1.638   1.734   1.859   2.017   2.109   2.264
200   L         0.334   0.254   0.126   0.330   0.211   0.053   0.296   0.166  -0.026
201   I         0.334   0.502   0.181   0.330   0.552   0.134   0.296   0.546   0.059
202   E        -0.695  -0.641  -0.603  -0.923  -0.829  -0.787  -0.799  -0.734  -0.663
203   K         1.049   0.910   0.889   0.972   0.798   0.754   1.078   0.828   0.756
204   Y         0.038   0.008  -0.009   0.169   0.115   0.106  -0.173  -0.229  -0.247
205   P         1.808   1.867   1.955   1.816   1.897   2.041   2.017   2.109   2.264
206   V         1.049   1.162   0.932   1.150   1.297   0.998   1.078   1.259   0.838
207   Q         1.808   1.867   1.955   1.892   1.978   2.119   2.017   2.109   2.264
208   T         0.700   0.764   0.732   0.600   0.692   0.618   0.453   0.555   0.443
209   S         0.334   0.464   0.171   0.350   0.532   0.091   0.296   0.491   0.043
210   S         0.334   0.402   0.156   0.402   0.492   0.154   0.296   0.399   0.020
211   R         1.808   1.867   1.955   1.849   1.927   2.074   2.017   2.109   2.264
212   T        -0.190  -0.190  -0.100  -0.394  -0.421  -0.286  -0.486  -0.486  -0.369
213   A         0.544   0.600   0.670   0.250   0.339   0.431   0.140   0.228   0.315
214   A         1.808   1.867   1.955   1.713   1.807   1.936   2.017   2.109   2.264
215   A         0.334   0.196   0.112   0.374   0.181   0.037   0.296   0.086  -0.048
216   M        -0.923  -0.982  -0.977  -0.837  -0.927  -0.890  -0.799  -0.853  -0.821
217   W         1.808   1.867   1.955   1.991   2.079   2.220   2.017   2.109   2.264
218   G         0.544   0.564   0.657   0.247   0.266   0.396   0.140   0.153   0.287
219   C         1.808   1.867   1.955   1.921   2.013   2.148   2.017   2.109   2.264
220   H        -0.557  -0.634  -0.579  -0.395  -0.526  -0.435  -0.643  -0.715  -0.636
221   I         0.700   0.808   0.776   0.624   0.785   0.721   0.453   0.639   0.533
222   H         1.808   1.867   1.955   1.910   1.996   2.137   2.017   2.109   2.264
223   N         1.808   1.867   1.955   1.856   1.930   2.082   2.017   2.109   2.264
224   K        -1.062  -0.984  -1.001  -1.043  -0.901  -0.973  -0.956  -0.864  -0.849
225   V         1.049   0.910   0.889   1.110   0.904   0.859   1.078   0.828   0.756
226   N         1.808   1.867   1.955   1.856   1.930   2.082   2.017   2.109   2.264
227   E         0.334   0.409   0.152   0.319   0.426   0.039   0.296   0.410   0.014
228   Y        -0.695  -0.638  -0.605  -0.704  -0.651  -0.570  -0.799  -0.729  -0.665
229   L         1.049   0.910   0.889   0.978   0.805   0.777   1.078   0.828   0.756
230   K        -0.557  -0.534  -0.554  -0.664  -0.625  -0.651  -0.643  -0.617  -0.610
231   K         1.049   0.910   0.889   0.987   0.822   0.785   1.078   0.828   0.756
232   D         0.038   0.113   0.029  -0.022   0.069  -0.050  -0.173  -0.077  -0.186
233   I        -1.062  -1.083  -1.007  -1.043  -1.095  -0.949  -0.956  -0.958  -0.854
234   Y         0.038  -0.073  -0.013   0.138  -0.026   0.055  -0.173  -0.319  -0.248
235   D         1.049   0.910   0.889   1.102   0.910   0.867   1.078   0.828   0.756
236   C         1.808   1.867   1.955   1.921   2.013   2.148   2.017   2.109   2.264
237   A        -0.923  -0.894  -0.958  -0.732  -0.709  -0.814  -0.799  -0.764  -0.801
238   T        -0.328  -0.455  -0.509  -0.202  -0.401  -0.498  -0.330  -0.487  -0.545
239   I         0.334   0.196   0.112   0.497   0.305   0.191   0.296   0.086  -0.048
240   L         0.038  -0.073  -0.013  -0.140  -0.290  -0.207  -0.173  -0.319  -0.248
241   E         1.049   1.084   0.917   1.002   1.056   0.825   1.078   1.131   0.811
242   D        -0.328  -0.455  -0.509  -0.097  -0.276  -0.333  -0.330  -0.487  -0.545
243   Y         1.808   1.867   1.955   1.881   1.970   2.108   2.017   2.109   2.264
244   D         0.334   0.196   0.112   0.435   0.238   0.087   0.296   0.086  -0.048
245   C         1.049   0.910   0.889   1.252   1.068   1.028   1.078   0.828   0.756
246   G         1.808   1.867   1.955   1.757   1.850   1.981   2.017   2.109   2.264
247   C         1.049   0.910   0.889   1.239   1.050   1.002   1.078   0.828   0.756
248   S        -0.923  -0.943  -0.959  -0.813  -0.846  -0.884  -0.799  -0.814  -0.802
249   D         0.334   0.196   0.112   0.435   0.234   0.088   0.296   0.086  -0.048
250   S        -1.062  -1.046  -1.009  -1.053  -1.018  -0.966  -0.956  -0.929  -0.855
251   D        -1.429  -1.401  -1.369  -1.315  -1.276  -1.219  -1.112  -1.074  -1.007
252   G        -1.062  -0.982  -1.007  -1.148  -1.031  -1.076  -0.956  -0.863  -0.853
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -         0.049   0.001   0.016  -0.066  -0.157  -0.137  -0.130  -0.205  -0.194
262   -        -1.172  -1.147  -1.060  -1.309  -1.271  -1.149  -1.050  -1.009  -0.899
263   -        -1.172  -1.147  -1.060  -1.184  -1.143  -1.021  -1.050  -1.009  -0.899
264   -        -0.659  -0.595  -0.580  -0.776  -0.679  -0.667  -0.743  -0.655  -0.631
265   -        -1.172  -1.147  -1.060  -1.163  -1.125  -0.999  -1.050  -1.009  -0.899
266   -        -0.659  -0.654  -0.597  -0.823  -0.813  -0.732  -0.743  -0.729  -0.651
267   -        -1.082  -1.080  -1.032  -1.141  -1.139  -1.068  -0.964  -0.949  -0.875
268   -        -1.510  -1.483  -1.401  -1.275  -1.268  -1.115  -1.177  -1.136  -1.031
269   K        -0.695  -0.728  -0.610  -0.771  -0.814  -0.642  -0.799  -0.813  -0.671
270   R        -0.923  -0.982  -0.977  -0.825  -0.909  -0.879  -0.799  -0.853  -0.821
271   V        -0.557  -0.610  -0.578  -0.555  -0.639  -0.581  -0.643  -0.695  -0.635
272   S        -0.923  -0.948  -0.973  -0.765  -0.817  -0.852  -0.799  -0.819  -0.816
273   L        -1.429  -1.433  -1.382  -1.394  -1.394  -1.311  -1.112  -1.099  -1.016
274   E        -0.190  -0.180  -0.095  -0.475  -0.459  -0.338  -0.486  -0.472  -0.362
275   K        -0.328  -0.455  -0.509  -0.347  -0.541  -0.638  -0.330  -0.487  -0.545
276   E         0.544   0.565   0.657   0.220   0.244   0.384   0.140   0.156   0.287
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   A        -1.795  -1.760  -1.690  -1.740  -1.623  -1.588  -1.269  -1.222  -1.125
284   K        -1.062  -0.982  -1.007  -1.077  -0.949  -0.974  -0.956  -0.863  -0.853
285   Q        -0.923  -0.992  -0.998  -0.683  -0.797  -0.835  -0.799  -0.863  -0.842
286   H        -1.429  -1.441  -1.383  -1.170  -1.214  -1.126  -1.112  -1.105  -1.018
287   G         0.334   0.348   0.143   0.411   0.442   0.119   0.296   0.321  -0.000
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12284
Output conservation file - output/Q12284
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
