1     M         2.024   2.038   2.078   2.371   2.392   2.459   2.254   2.275   2.338
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -         2.024   2.038   2.078   1.929   1.945   2.023   2.254   2.275   2.338
21    -        -0.469  -0.443  -0.391  -0.710  -0.653  -0.584  -0.615  -0.580  -0.508
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    K        -0.370  -0.376  -0.351  -0.276  -0.255  -0.215  -0.501  -0.498  -0.459
29    L         0.497   0.489   0.528   0.068   0.069   0.146   0.188   0.167   0.219
30    L        -0.370  -0.374  -0.325  -0.738  -0.745  -0.639  -0.501  -0.500  -0.429
31    T         0.889   0.836   0.751   0.979   0.903   0.751   0.877   0.787   0.626
32    F         0.497   0.489   0.528   0.605   0.594   0.658   0.188   0.167   0.219
33    P         2.024   2.038   2.078   2.223   2.249   2.313   2.254   2.275   2.338
34    G         2.024   2.038   2.078   2.189   2.204   2.279   2.254   2.275   2.338
35    Q         2.024   2.038   2.078   2.238   2.260   2.328   2.254   2.275   2.338
36    G         2.024   2.038   2.078   2.189   2.204   2.279   2.254   2.275   2.338
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    T        -0.999  -1.051  -1.016  -1.115  -1.227  -1.197  -0.845  -0.896  -0.843
43    S        -0.999  -0.921  -0.985  -1.251  -1.135  -1.201  -0.845  -0.758  -0.810
44    I        -0.370  -0.365  -0.329  -0.496  -0.479  -0.402  -0.501  -0.486  -0.430
45    S        -0.370  -0.296  -0.317  -0.665  -0.566  -0.579  -0.501  -0.414  -0.422
46    I        -0.999  -0.982  -0.949  -1.024  -1.012  -0.954  -0.845  -0.825  -0.772
47    S        -0.999  -0.985  -0.953  -0.881  -0.852  -0.816  -0.845  -0.828  -0.776
48    I        -1.628  -1.597  -1.540  -1.452  -1.390  -1.315  -1.189  -1.155  -1.078
49    L        -0.132  -0.187  -0.278  -0.289  -0.352  -0.453  -0.156  -0.231  -0.356
50    K         0.497   0.485   0.527   0.406   0.385   0.460   0.188   0.159   0.217
51    A        -0.999  -1.051  -1.016  -0.760  -0.835  -0.786  -0.845  -0.896  -0.843
52    I        -0.999  -0.982  -0.949  -1.029  -0.970  -0.929  -0.845  -0.825  -0.772
53    I        -0.370  -0.376  -0.351  -0.391  -0.373  -0.331  -0.501  -0.498  -0.459
54    R        -0.370  -0.376  -0.351  -0.205  -0.204  -0.169  -0.501  -0.498  -0.459
55    N        -0.132  -0.187  -0.278   0.000  -0.065  -0.193  -0.156  -0.231  -0.356
56    K        -0.999  -1.051  -1.016  -0.917  -1.001  -0.943  -0.845  -0.896  -0.843
57    S        -0.370  -0.313  -0.342  -0.782  -0.712  -0.706  -0.501  -0.433  -0.449
58    R        -1.122  -1.097  -1.038  -0.912  -0.875  -0.782  -0.974  -0.943  -0.864
59    E        -0.335  -0.316  -0.295  -0.330  -0.314  -0.270  -0.436  -0.409  -0.380
60    F        -0.335  -0.377  -0.367  -0.436  -0.539  -0.571  -0.436  -0.491  -0.476
61    Q        -0.335  -0.246  -0.332  -0.227  -0.066  -0.235  -0.436  -0.312  -0.429
62    T        -0.335  -0.377  -0.367  -0.314  -0.385  -0.368  -0.436  -0.491  -0.476
63    I        -0.335  -0.377  -0.367  -0.471  -0.548  -0.527  -0.436  -0.491  -0.476
64    L         2.024   2.038   2.078   1.707   1.734   1.803   2.254   2.275   2.338
65    S         0.748   0.820   0.704   0.690   0.821   0.606   0.640   0.759   0.543
66    Q        -1.122  -1.097  -1.038  -0.811  -0.768  -0.683  -0.974  -0.943  -0.864
67    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    G         0.497   0.489   0.528   0.410   0.379   0.443   0.188   0.167   0.219
69    K        -0.132   0.028  -0.195  -0.020   0.250  -0.156  -0.156   0.066  -0.243
70    E        -0.999  -0.921  -0.985  -0.946  -0.846  -0.904  -0.845  -0.758  -0.810
71    S        -0.132   0.028  -0.195   0.075   0.326  -0.032  -0.156   0.066  -0.243
72    N        -0.999  -0.921  -0.985  -0.894  -0.778  -0.869  -0.845  -0.758  -0.810
73    D        -0.370  -0.376  -0.351  -0.683  -0.720  -0.676  -0.501  -0.498  -0.459
74    L         0.889   0.855   0.743   0.667   0.630   0.478   0.877   0.818   0.613
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    L        -0.370  -0.376  -0.351  -0.765  -0.739  -0.700  -0.501  -0.498  -0.459
84    Q        -0.370  -0.386  -0.318  -0.286  -0.303  -0.197  -0.501  -0.513  -0.422
85    Y        -0.370  -0.376  -0.351  -0.044  -0.031   0.001  -0.501  -0.498  -0.459
86    I        -0.370  -0.376  -0.351  -0.733  -0.740  -0.674  -0.501  -0.498  -0.459
87    F        -0.999  -1.051  -1.016  -0.899  -1.005  -0.972  -0.845  -0.896  -0.843
88    Q        -1.628  -1.597  -1.540  -1.194  -1.157  -1.061  -1.189  -1.155  -1.078
89    N         0.497   0.574   0.598   0.312   0.470   0.492   0.188   0.325   0.349
90    P        -0.999  -1.051  -1.016  -0.989  -1.107  -1.080  -0.845  -0.896  -0.843
91    S        -0.370  -0.376  -0.351  -0.596  -0.580  -0.540  -0.501  -0.498  -0.459
92    S        -0.370  -0.376  -0.351  -0.443  -0.419  -0.373  -0.501  -0.498  -0.459
93    P         0.497   0.489   0.528   0.533   0.518   0.577   0.188   0.167   0.219
94    G        -0.370  -0.376  -0.351  -0.278  -0.278  -0.241  -0.501  -0.498  -0.459
95    S        -0.370  -0.376  -0.351  -0.489  -0.468  -0.431  -0.501  -0.498  -0.459
96    I         2.024   2.038   2.078   1.993   2.009   2.085   2.254   2.275   2.338
97    A         0.497   0.489   0.528   0.199   0.161   0.202   0.188   0.167   0.219
98    V         0.497   0.574   0.598   0.413   0.554   0.589   0.188   0.325   0.349
99    C        -0.132  -0.187  -0.278   0.176   0.082  -0.109  -0.156  -0.231  -0.356
100   S         0.497   0.489   0.528   0.223   0.213   0.278   0.188   0.167   0.219
101   N        -0.132  -0.187  -0.278   0.038  -0.023  -0.141  -0.156  -0.231  -0.356
102   L        -0.370  -0.313  -0.342  -0.733  -0.652  -0.657  -0.501  -0.433  -0.449
103   F        -0.132  -0.068  -0.182  -0.373  -0.286  -0.432  -0.156  -0.071  -0.224
104   Y        -0.132  -0.187  -0.278   0.173   0.090  -0.073  -0.156  -0.231  -0.356
105   Q        -0.999  -0.985  -0.953  -0.926  -0.925  -0.859  -0.845  -0.828  -0.776
106   L        -0.999  -0.997  -0.951  -1.184  -1.192  -1.092  -0.845  -0.840  -0.774
107   Y        -0.999  -1.051  -1.016  -0.676  -0.762  -0.716  -0.845  -0.896  -0.843
108   Q        -1.628  -1.597  -1.540  -1.450  -1.431  -1.313  -1.189  -1.155  -1.078
109   I        -1.122  -1.097  -1.038  -1.403  -1.339  -1.268  -0.974  -0.943  -0.864
110   L        -0.335  -0.246  -0.332  -0.548  -0.380  -0.582  -0.436  -0.312  -0.429
111   S        -0.335  -0.377  -0.367  -0.308  -0.355  -0.314  -0.436  -0.491  -0.476
112   N        -1.122  -1.097  -1.038  -1.008  -0.955  -0.878  -0.974  -0.943  -0.864
113   P        -0.335  -0.246  -0.332  -0.346  -0.217  -0.327  -0.436  -0.312  -0.429
114   S        -0.335  -0.316  -0.295  -0.590  -0.537  -0.531  -0.436  -0.409  -0.380
115   D        -1.122  -1.097  -1.038  -1.221  -1.212  -1.087  -0.974  -0.943  -0.864
116   P         0.748   0.712   0.666   0.849   0.783   0.691   0.640   0.574   0.474
117   Q         0.580   0.678   0.614   0.734   0.891   0.786   0.341   0.513   0.379
118   D        -0.469  -0.412  -0.391  -0.448  -0.371  -0.325  -0.615  -0.539  -0.508
119   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   N        -0.370  -0.313  -0.342  -0.365  -0.276  -0.302  -0.501  -0.433  -0.449
136   E        -1.628  -1.597  -1.540  -1.422  -1.382  -1.286  -1.189  -1.155  -1.078
137   Q        -1.628  -1.597  -1.540  -1.456  -1.415  -1.319  -1.189  -1.155  -1.078
138   C        -1.628  -1.597  -1.540  -1.620  -1.574  -1.482  -1.189  -1.155  -1.078
139   Y        -0.132  -0.092  -0.193   0.149   0.219   0.042  -0.156  -0.102  -0.240
140   L         0.889   0.836   0.751   0.634   0.563   0.441   0.877   0.787   0.626
141   L         0.889   0.836   0.751   0.603   0.529   0.396   0.877   0.787   0.626
142   G         2.024   2.038   2.078   2.189   2.204   2.279   2.254   2.275   2.338
143   H         2.024   2.038   2.078   2.311   2.335   2.399   2.254   2.275   2.338
144   S         2.024   2.038   2.078   1.945   1.967   2.038   2.254   2.275   2.338
145   L         2.024   2.038   2.078   1.723   1.750   1.819   2.254   2.275   2.338
146   G         2.024   2.038   2.078   2.189   2.204   2.279   2.254   2.275   2.338
147   E         2.024   2.038   2.078   2.123   2.143   2.214   2.254   2.275   2.338
148   L         0.497   0.489   0.528   0.132   0.140   0.219   0.188   0.167   0.219
149   T         0.889   0.836   0.751   0.996   0.925   0.776   0.877   0.787   0.626
150   C         0.497   0.574   0.598   0.554   0.677   0.716   0.188   0.325   0.349
151   L         2.024   2.038   2.078   1.723   1.750   1.819   2.254   2.275   2.338
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   S        -0.999  -0.989  -0.983  -1.207  -1.205  -1.192  -0.845  -0.831  -0.808
155   V         0.497   0.489   0.528   0.143   0.100   0.151   0.188   0.167   0.219
156   N        -0.132  -0.187  -0.278  -0.127  -0.206  -0.370  -0.156  -0.231  -0.356
157   S        -0.132   0.028  -0.195   0.022   0.271  -0.094  -0.156   0.066  -0.243
158   L        -0.132  -0.187  -0.278  -0.417  -0.500  -0.632  -0.156  -0.231  -0.356
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   F        -0.132  -0.187  -0.278  -0.044  -0.147  -0.360  -0.156  -0.231  -0.356
161   S        -0.999  -0.921  -0.985  -0.845  -0.707  -0.837  -0.845  -0.758  -0.810
162   L        -0.999  -1.000  -0.952  -1.043  -1.012  -0.945  -0.845  -0.843  -0.775
163   K         0.497   0.489   0.528   0.332   0.315   0.377   0.188   0.167   0.219
164   D        -0.999  -0.989  -0.983  -0.774  -0.760  -0.755  -0.845  -0.831  -0.808
165   L        -0.999  -1.051  -1.016  -1.200  -1.255  -1.168  -0.845  -0.896  -0.843
166   F         0.497   0.574   0.598   0.335   0.454   0.500   0.188   0.325   0.349
167   D        -0.999  -0.973  -0.977  -0.793  -0.758  -0.755  -0.845  -0.815  -0.802
168   I        -0.132  -0.187  -0.278  -0.240  -0.343  -0.519  -0.156  -0.231  -0.356
169   A         0.497   0.489   0.528   0.413   0.387   0.450   0.188   0.167   0.219
170   N        -0.370  -0.376  -0.351  -0.433  -0.414  -0.397  -0.501  -0.498  -0.459
171   F        -0.999  -0.989  -0.983  -0.659  -0.644  -0.633  -0.845  -0.831  -0.808
172   R         2.024   2.038   2.078   2.257   2.284   2.347   2.254   2.275   2.338
173   N         0.497   0.489   0.528   0.330   0.320   0.386   0.188   0.167   0.219
174   K        -0.999  -0.908  -0.950  -0.701  -0.552  -0.628  -0.845  -0.742  -0.773
175   L         2.024   2.038   2.078   1.723   1.750   1.819   2.254   2.275   2.338
176   M         2.024   2.038   2.078   2.371   2.392   2.459   2.254   2.275   2.338
177   V         0.497   0.489   0.528   0.369   0.343   0.412   0.188   0.167   0.219
178   T        -0.999  -0.911  -0.953  -0.852  -0.711  -0.782  -0.845  -0.745  -0.776
179   S        -0.999  -0.921  -0.985  -1.182  -1.064  -1.124  -0.845  -0.758  -0.810
180   T         2.024   2.038   2.078   2.067   2.095   2.159   2.254   2.275   2.338
181   E         0.580   0.510   0.546   0.644   0.534   0.585   0.341   0.208   0.253
182   K        -0.469  -0.429  -0.391  -0.393  -0.327  -0.270  -0.615  -0.561  -0.508
183   Y         2.024   2.038   2.078   2.269   2.299   2.358   2.254   2.275   2.338
184   L         2.024   2.038   2.078   1.752   1.787   1.848   2.254   2.275   2.338
185   V        -0.469  -0.429  -0.391  -0.455  -0.385  -0.332  -0.615  -0.561  -0.508
186   A         0.580   0.510   0.546   0.603   0.465   0.521   0.341   0.208   0.253
187   H        -0.469  -0.429  -0.391  -0.238  -0.165  -0.117  -0.615  -0.561  -0.508
188   N         0.580   0.510   0.546   0.424   0.308   0.375   0.341   0.208   0.253
189   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   N        -1.628  -1.597  -1.540  -1.354  -1.306  -1.219  -1.189  -1.155  -1.078
191   R        -0.370  -0.365  -0.329  -0.367  -0.363  -0.319  -0.501  -0.486  -0.430
192   S        -0.999  -0.982  -0.949  -0.888  -0.855  -0.817  -0.845  -0.825  -0.772
193   N        -0.999  -1.000  -0.952  -0.938  -0.917  -0.860  -0.845  -0.843  -0.775
194   K        -0.999  -1.051  -1.016  -0.985  -1.076  -1.026  -0.845  -0.896  -0.843
195   F         0.497   0.489   0.528   0.558   0.546   0.604   0.188   0.167   0.219
196   E        -0.132  -0.187  -0.278  -0.020  -0.111  -0.271  -0.156  -0.231  -0.356
197   M         0.889   0.836   0.751   1.185   1.096   0.923   0.877   0.787   0.626
198   W        -0.132  -0.187  -0.278   0.247   0.147  -0.038  -0.156  -0.231  -0.356
199   A         2.024   2.038   2.078   2.169   2.191   2.260   2.254   2.275   2.338
200   L         0.889   0.836   0.751   0.634   0.563   0.441   0.877   0.787   0.626
201   S        -0.999  -1.051  -1.016  -1.068  -1.141  -1.083  -0.845  -0.896  -0.843
202   S        -0.999  -1.051  -1.016  -1.060  -1.135  -1.073  -0.845  -0.896  -0.843
203   P        -0.370  -0.376  -0.351  -0.363  -0.378  -0.333  -0.501  -0.498  -0.459
204   R        -0.370  -0.313  -0.342  -0.248  -0.158  -0.203  -0.501  -0.433  -0.449
205   A        -0.370  -0.365  -0.329  -0.503  -0.506  -0.445  -0.501  -0.486  -0.430
206   T         0.580   0.510   0.546   0.490   0.366   0.421   0.341   0.208   0.253
207   D         0.580   0.510   0.546   0.485   0.324   0.382   0.341   0.208   0.253
208   L         0.497   0.489   0.528   0.106   0.111   0.189   0.188   0.167   0.219
209   P        -0.999  -1.051  -1.016  -0.664  -0.734  -0.687  -0.845  -0.896  -0.843
210   Q        -0.999  -0.908  -0.950  -0.796  -0.673  -0.714  -0.845  -0.742  -0.773
211   E         0.889   0.836   0.751   1.053   0.978   0.853   0.877   0.787   0.626
212   V        -0.370  -0.386  -0.318  -0.639  -0.683  -0.560  -0.501  -0.513  -0.422
213   Q        -1.628  -1.597  -1.540  -1.618  -1.622  -1.480  -1.189  -1.155  -1.078
214   K        -0.999  -1.051  -1.016  -1.044  -1.140  -1.097  -0.845  -0.896  -0.843
215   L        -0.132  -0.201  -0.237  -0.285  -0.372  -0.398  -0.156  -0.250  -0.300
216   L        -0.132  -0.187  -0.278  -0.411  -0.488  -0.624  -0.156  -0.231  -0.356
217   N        -0.999  -0.921  -0.985  -0.780  -0.642  -0.773  -0.845  -0.758  -0.810
218   S         0.497   0.520   0.557   0.281   0.322   0.377   0.188   0.225   0.273
219   P        -0.469  -0.429  -0.391  -0.700  -0.649  -0.573  -0.615  -0.561  -0.508
220   N        -0.469  -0.429  -0.391  -0.653  -0.587  -0.526  -0.615  -0.561  -0.508
221   L         0.580   0.669   0.588   0.315   0.505   0.296   0.341   0.497   0.332
222   L        -0.469  -0.429  -0.391  -0.818  -0.747  -0.689  -0.615  -0.561  -0.508
223   S         0.580   0.641   0.583   0.407   0.507   0.417   0.341   0.447   0.321
224   S         0.580   0.641   0.583   0.401   0.494   0.410   0.341   0.447   0.321
225   S         0.580   0.510   0.546   0.371   0.249   0.316   0.341   0.208   0.253
226   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   N        -0.469  -0.429  -0.391  -0.415  -0.325  -0.292  -0.615  -0.561  -0.508
230   T        -0.999  -1.051  -1.016  -0.843  -0.919  -0.867  -0.845  -0.896  -0.843
231   I        -0.132  -0.187  -0.278  -0.142  -0.231  -0.380  -0.156  -0.231  -0.356
232   S        -0.370  -0.376  -0.351  -0.549  -0.542  -0.496  -0.501  -0.498  -0.459
233   V         0.497   0.574   0.598   0.029   0.151   0.196   0.188   0.325   0.349
234   A         0.889   0.855   0.743   1.096   1.048   0.880   0.877   0.818   0.613
235   N         2.024   2.038   2.078   2.016   2.046   2.109   2.254   2.275   2.338
236   A        -0.999  -1.051  -1.016  -0.848  -0.942  -0.891  -0.845  -0.896  -0.843
237   N         2.024   2.038   2.078   2.016   2.046   2.109   2.254   2.275   2.338
238   S         0.889   0.836   0.751   0.870   0.798   0.675   0.877   0.787   0.626
239   V        -0.132  -0.187  -0.278   0.015  -0.071  -0.215  -0.156  -0.231  -0.356
240   K        -0.999  -1.051  -1.016  -0.833  -0.903  -0.843  -0.845  -0.896  -0.843
241   Q         2.024   2.038   2.078   2.238   2.260   2.328   2.254   2.275   2.338
242   C        -0.132  -0.187  -0.278   0.188   0.090  -0.091  -0.156  -0.231  -0.356
243   V         2.024   2.038   2.078   2.107   2.121   2.198   2.254   2.275   2.338
244   V        -0.370  -0.362  -0.327  -0.639  -0.645  -0.592  -0.501  -0.482  -0.427
245   T         0.497   0.489   0.528   0.271   0.248   0.299   0.188   0.167   0.219
246   G         2.024   2.038   2.078   2.189   2.204   2.279   2.254   2.275   2.338
247   L        -0.132  -0.187  -0.278  -0.384  -0.460  -0.586  -0.156  -0.231  -0.356
248   V        -0.370  -0.365  -0.329  -0.577  -0.583  -0.517  -0.501  -0.486  -0.430
249   D        -1.628  -1.597  -1.540  -1.527  -1.491  -1.390  -1.189  -1.155  -1.078
250   D         0.497   0.489   0.528   0.420   0.394   0.452   0.188   0.167   0.219
251   L         0.497   0.485   0.527  -0.042  -0.060   0.019   0.188   0.159   0.217
252   E        -0.999  -1.051  -1.016  -0.801  -0.878  -0.820  -0.845  -0.896  -0.843
253   S        -0.999  -0.911  -0.953  -0.954  -0.812  -0.884  -0.845  -0.745  -0.776
254   L        -0.132  -0.187  -0.278  -0.333  -0.398  -0.514  -0.156  -0.231  -0.356
255   R        -0.370  -0.376  -0.351  -0.393  -0.417  -0.368  -0.501  -0.498  -0.459
256   T        -0.999  -1.051  -1.016  -0.818  -0.890  -0.837  -0.845  -0.896  -0.843
257   E        -0.132  -0.205  -0.238  -0.029  -0.151  -0.214  -0.156  -0.256  -0.302
258   L        -0.132  -0.201  -0.237  -0.329  -0.416  -0.455  -0.156  -0.250  -0.300
259   N        -0.999  -1.000  -0.952  -0.832  -0.831  -0.750  -0.845  -0.843  -0.775
260   L        -0.999  -1.051  -1.016  -1.180  -1.222  -1.144  -0.845  -0.896  -0.843
261   R        -0.999  -0.911  -0.953  -0.899  -0.768  -0.831  -0.845  -0.745  -0.776
262   F        -1.628  -1.597  -1.540  -1.510  -1.469  -1.374  -1.189  -1.155  -1.078
263   P        -0.370  -0.376  -0.351  -0.495  -0.522  -0.503  -0.501  -0.498  -0.459
264   R         0.748   0.620   0.630   1.020   0.839   0.845   0.640   0.409   0.409
265   L        -0.999  -1.051  -1.016  -1.108  -1.141  -1.060  -0.845  -0.896  -0.843
266   R        -0.999  -1.051  -1.016  -0.980  -1.103  -1.082  -0.845  -0.896  -0.843
267   I        -0.132  -0.201  -0.237  -0.198  -0.314  -0.386  -0.156  -0.250  -0.300
268   T        -0.370  -0.313  -0.342  -0.500  -0.411  -0.457  -0.501  -0.433  -0.449
269   E        -0.999  -1.051  -1.016  -0.865  -0.950  -0.897  -0.845  -0.896  -0.843
270   L         0.497   0.489   0.528   0.029   0.022   0.101   0.188   0.167   0.219
271   T        -0.999  -1.051  -1.016  -0.810  -0.881  -0.827  -0.845  -0.896  -0.843
272   N        -0.370  -0.376  -0.351  -0.828  -0.842  -0.803  -0.501  -0.498  -0.459
273   P         2.024   2.038   2.078   2.223   2.249   2.313   2.254   2.275   2.338
274   Y        -0.999  -0.921  -0.985  -0.692  -0.594  -0.651  -0.845  -0.758  -0.810
275   N        -0.370  -0.362  -0.327  -0.615  -0.595  -0.534  -0.501  -0.482  -0.427
276   I         0.889   0.977   0.783   0.807   0.942   0.619   0.877   1.017   0.683
277   P         2.024   2.038   2.078   2.223   2.249   2.313   2.254   2.275   2.338
278   F         2.024   2.038   2.078   2.231   2.254   2.321   2.254   2.275   2.338
279   H         2.024   2.038   2.078   2.311   2.335   2.399   2.254   2.275   2.338
280   N         0.889   0.855   0.743   0.885   0.842   0.647   0.877   0.818   0.613
281   S        -0.469  -0.429  -0.391  -0.834  -0.761  -0.706  -0.615  -0.561  -0.508
282   T        -0.132  -0.205  -0.238  -0.029  -0.141  -0.210  -0.156  -0.256  -0.302
283   V         0.497   0.489   0.528   0.295   0.260   0.327   0.188   0.167   0.219
284   L         2.024   2.038   2.078   1.723   1.750   1.819   2.254   2.275   2.338
285   R        -0.132  -0.187  -0.278   0.183   0.104  -0.052  -0.156  -0.231  -0.356
286   P        -0.132  -0.201  -0.237   0.055  -0.060  -0.139  -0.156  -0.250  -0.300
287   V         0.497   0.526   0.539   0.262   0.304   0.331   0.188   0.237   0.240
288   Q        -0.132  -0.187  -0.278   0.118   0.028  -0.134  -0.156  -0.231  -0.356
289   E         0.497   0.489   0.528   0.440   0.426   0.490   0.188   0.167   0.219
290   P        -0.132  -0.187  -0.278   0.093   0.007  -0.161  -0.156  -0.231  -0.356
291   L         2.024   2.038   2.078   1.723   1.750   1.819   2.254   2.275   2.338
292   Y        -0.132  -0.187  -0.278   0.021  -0.077  -0.288  -0.156  -0.231  -0.356
293   D        -0.132  -0.187  -0.278   0.069  -0.019  -0.184  -0.156  -0.231  -0.356
294   Y        -0.370  -0.298  -0.340  -0.537  -0.456  -0.457  -0.501  -0.417  -0.447
295   I        -0.132  -0.187  -0.278  -0.219  -0.318  -0.489  -0.156  -0.231  -0.356
296   W         0.748   0.620   0.630   1.116   0.896   0.897   0.640   0.409   0.409
297   D        -0.999  -0.989  -0.983  -0.794  -0.778  -0.778  -0.845  -0.831  -0.808
298   I        -0.999  -1.051  -1.016  -0.908  -0.975  -0.908  -0.845  -0.896  -0.843
299   L         0.889   0.977   0.783   0.705   0.827   0.589   0.877   1.017   0.683
300   K        -0.132  -0.187  -0.278  -0.029  -0.113  -0.260  -0.156  -0.231  -0.356
301   K        -0.469  -0.429  -0.391  -0.606  -0.528  -0.480  -0.615  -0.561  -0.508
302   N         2.024   2.038   2.078   1.960   1.974   2.053   2.254   2.275   2.338
303   G         2.024   2.038   2.078   2.202   2.217   2.293   2.254   2.275   2.338
304   T         0.580   0.510   0.546   0.490   0.366   0.421   0.341   0.208   0.253
305   H         2.024   2.038   2.078   2.287   2.312   2.376   2.254   2.275   2.338
306   T         0.580   0.510   0.546   0.561   0.460   0.513   0.341   0.208   0.253
307   L        -0.469  -0.429  -0.391  -0.526  -0.436  -0.401  -0.615  -0.561  -0.508
308   M        -0.469  -0.429  -0.391  -0.481  -0.441  -0.357  -0.615  -0.561  -0.508
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   E        -0.999  -0.911  -0.953  -0.873  -0.738  -0.799  -0.845  -0.745  -0.776
312   L        -0.999  -1.051  -1.016  -1.101  -1.139  -1.051  -0.845  -0.896  -0.843
313   N        -0.999  -1.051  -1.016  -0.972  -1.044  -0.992  -0.845  -0.896  -0.843
314   H        -0.999  -1.051  -1.016  -0.819  -0.931  -0.902  -0.845  -0.896  -0.843
315   P         0.889   0.836   0.751   1.148   1.076   0.943   0.877   0.787   0.626
316   I         2.024   2.038   2.078   1.993   2.009   2.085   2.254   2.275   2.338
317   I        -0.370  -0.386  -0.318  -0.457  -0.476  -0.363  -0.501  -0.513  -0.422
318   A         0.497   0.529   0.542   0.257   0.310   0.336   0.188   0.241   0.245
319   N         2.024   2.038   2.078   2.016   2.046   2.109   2.254   2.275   2.338
320   L         0.889   0.836   0.751   0.603   0.529   0.396   0.877   0.787   0.626
321   D        -0.132  -0.187  -0.278   0.091   0.008  -0.154  -0.156  -0.231  -0.356
322   G         2.024   2.038   2.078   2.189   2.204   2.279   2.254   2.275   2.338
323   N        -0.999  -0.973  -0.977  -0.896  -0.848  -0.859  -0.845  -0.815  -0.802
324   I        -0.999  -0.921  -0.985  -1.090  -0.982  -1.097  -0.845  -0.758  -0.810
325   S         0.497   0.512   0.553   0.223   0.251   0.318   0.188   0.210   0.266
326   Y        -0.132  -0.092  -0.193   0.170   0.238   0.068  -0.156  -0.102  -0.240
327   Y        -1.628  -1.597  -1.540  -1.196  -1.156  -1.063  -1.189  -1.155  -1.078
328   I        -0.999  -1.051  -1.016  -0.899  -0.966  -0.897  -0.845  -0.896  -0.843
329   H        -0.999  -1.051  -1.016  -0.636  -0.721  -0.679  -0.845  -0.896  -0.843
330   H        -0.370  -0.365  -0.329  -0.330  -0.331  -0.288  -0.501  -0.486  -0.430
331   A        -0.132  -0.187  -0.278   0.127   0.051  -0.088  -0.156  -0.231  -0.356
332   L        -0.132  -0.187  -0.278  -0.416  -0.494  -0.630  -0.156  -0.231  -0.356
333   D        -0.335  -0.412  -0.367  -0.214  -0.325  -0.266  -0.436  -0.541  -0.476
334   R        -0.335  -0.158  -0.294  -0.393  -0.110  -0.324  -0.436  -0.191  -0.379
335   F         0.748   0.620   0.630   0.883   0.647   0.652   0.640   0.409   0.409
336   V        -0.132  -0.187  -0.278  -0.165  -0.276  -0.470  -0.156  -0.231  -0.356
337   K        -0.999  -1.051  -1.016  -0.826  -0.896  -0.834  -0.845  -0.896  -0.843
338   C        -0.370  -0.376  -0.351  -0.178  -0.194  -0.150  -0.501  -0.498  -0.459
339   S         0.497   0.489   0.528   0.167   0.154   0.214   0.188   0.167   0.219
340   S        -0.132  -0.205  -0.238  -0.028  -0.119  -0.148  -0.156  -0.256  -0.302
341   R        -1.628  -1.597  -1.540  -1.373  -1.332  -1.238  -1.189  -1.155  -1.078
342   T        -0.370  -0.376  -0.351  -0.376  -0.370  -0.344  -0.501  -0.498  -0.459
343   V         2.024   2.038   2.078   2.107   2.121   2.198   2.254   2.275   2.338
344   Q         0.889   0.836   0.751   1.122   1.044   0.897   0.877   0.787   0.626
345   F         0.497   0.489   0.528   0.641   0.632   0.698   0.188   0.167   0.219
346   T        -0.132  -0.205  -0.238   0.035  -0.073  -0.125  -0.156  -0.256  -0.302
347   M        -0.132  -0.088  -0.194   0.070   0.121  -0.003  -0.156  -0.100  -0.241
348   C         0.497   0.574   0.598   0.368   0.479   0.525   0.188   0.325   0.349
349   Y        -0.999  -1.051  -1.016  -0.599  -0.675  -0.624  -0.845  -0.896  -0.843
350   D        -0.999  -1.051  -1.016  -0.798  -0.889  -0.840  -0.845  -0.896  -0.843
351   T        -0.370  -0.376  -0.351  -0.332  -0.318  -0.297  -0.501  -0.498  -0.459
352   I         0.497   0.489   0.528   0.039   0.001   0.055   0.188   0.167   0.219
353   N        -0.999  -1.051  -1.016  -1.027  -1.112  -1.058  -0.845  -0.896  -0.843
354   S        -0.999  -0.989  -0.983  -0.997  -0.983  -0.958  -0.845  -0.831  -0.808
355   G        -0.469  -0.429  -0.391  -0.789  -0.763  -0.661  -0.615  -0.561  -0.508
356   T        -0.999  -0.908  -0.950  -1.036  -0.900  -0.954  -0.845  -0.742  -0.773
357   P        -0.999  -0.997  -0.951  -0.891  -0.899  -0.827  -0.845  -0.840  -0.774
358   V         0.889   0.977   0.783   1.030   1.148   0.880   0.877   1.017   0.683
359   E        -0.370  -0.377  -0.327  -0.464  -0.472  -0.397  -0.501  -0.503  -0.432
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   K        -0.999  -0.989  -0.983  -0.854  -0.839  -0.822  -0.845  -0.831  -0.808
369   S        -0.999  -0.973  -0.977  -0.952  -0.914  -0.938  -0.845  -0.815  -0.802
370   I        -0.132  -0.205  -0.238  -0.024  -0.127  -0.160  -0.156  -0.256  -0.302
371   C        -0.370  -0.376  -0.351  -0.237  -0.248  -0.200  -0.501  -0.498  -0.459
372   F        -0.370  -0.313  -0.342  -0.642  -0.570  -0.588  -0.501  -0.433  -0.449
373   G         2.024   2.038   2.078   2.189   2.204   2.279   2.254   2.275   2.338
374   P         2.024   2.038   2.078   2.223   2.249   2.313   2.254   2.275   2.338
375   G         2.024   2.038   2.078   2.189   2.204   2.279   2.254   2.275   2.338
376   N        -0.999  -1.051  -1.016  -0.918  -0.982  -0.927  -0.845  -0.896  -0.843
377   V        -0.132  -0.205  -0.238  -0.041  -0.168  -0.223  -0.156  -0.256  -0.302
378   I         0.497   0.489   0.528   0.039   0.001   0.055   0.188   0.167   0.219
379   Y        -0.999  -1.051  -1.016  -0.595  -0.671  -0.619  -0.845  -0.896  -0.843
380   N        -0.370  -0.376  -0.351  -0.439  -0.428  -0.391  -0.501  -0.498  -0.459
381   L         0.889   0.855   0.743   0.603   0.558   0.383   0.877   0.818   0.613
382   I         0.497   0.489   0.528   0.209   0.189   0.252   0.188   0.167   0.219
383   R        -0.999  -1.051  -1.016  -0.840  -0.943  -0.909  -0.845  -0.896  -0.843
384   R         0.497   0.489   0.528   0.469   0.445   0.497   0.188   0.167   0.219
385   N        -0.132  -0.187  -0.278  -0.002  -0.067  -0.196  -0.156  -0.231  -0.356
386   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   Q        -1.122  -1.097  -1.038  -1.168  -1.120  -1.035  -0.974  -0.943  -0.864
389   V         0.748   0.815   0.705   0.682   0.795   0.580   0.640   0.752   0.546
390   D        -0.335  -0.313  -0.293  -0.262  -0.220  -0.191  -0.436  -0.406  -0.377
391   T        -1.122  -1.097  -1.038  -1.061  -1.033  -0.929  -0.974  -0.943  -0.864
392   I        -0.335  -0.313  -0.293  -0.312  -0.277  -0.247  -0.436  -0.406  -0.377
393   E         0.451   0.474   0.528   0.175   0.200   0.296   0.102   0.140   0.217
394   Y        -0.335  -0.377  -0.367  -0.370  -0.469  -0.493  -0.436  -0.491  -0.476
395   T        -0.335  -0.246  -0.332  -0.306  -0.143  -0.326  -0.436  -0.312  -0.429
396   S         0.748   0.712   0.666   0.697   0.644   0.576   0.640   0.574   0.474
397   L        -0.370  -0.313  -0.342  -0.592  -0.515  -0.510  -0.501  -0.433  -0.449
398   A        -0.370  -0.362  -0.327  -0.396  -0.386  -0.323  -0.501  -0.482  -0.427
399   T         0.497   0.489   0.528   0.271   0.248   0.299   0.188   0.167   0.219
400   I        -0.999  -1.051  -1.016  -0.921  -0.989  -0.923  -0.845  -0.896  -0.843
401   D         0.889   0.861   0.748   1.084   1.046   0.856   0.877   0.828   0.622
402   A        -1.628  -1.597  -1.540  -1.577  -1.538  -1.439  -1.189  -1.155  -1.078
403   Y        -0.335  -0.412  -0.367  -0.320  -0.490  -0.435  -0.436  -0.541  -0.476
404   H         0.748   0.620   0.630   0.938   0.700   0.695   0.640   0.409   0.409
405   K        -1.122  -1.068  -1.038  -1.099  -1.020  -0.967  -0.974  -0.915  -0.864
406   A        -0.335  -0.158  -0.294  -0.203   0.093  -0.143  -0.436  -0.191  -0.379
407   A        -1.122  -1.068  -1.038  -0.859  -0.771  -0.730  -0.974  -0.915  -0.864
408   E         0.451   0.469   0.522   0.343   0.374   0.460   0.102   0.130   0.208
409   E         0.580   0.680   0.616   0.154   0.302   0.221   0.341   0.516   0.384
410   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
411   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
412   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
413   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
414   N        -0.469  -0.445  -0.391  -0.555  -0.520  -0.430  -0.615  -0.582  -0.508
415   K        -0.469  -0.445  -0.391  -0.686  -0.639  -0.559  -0.615  -0.582  -0.508
416   D        -0.469  -0.445  -0.391  -0.490  -0.444  -0.366  -0.615  -0.582  -0.508
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12283
Output conservation file - output/Q12283
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
