1     M         2.122   2.163   2.282   2.448   2.509   2.700   2.440   2.504   2.707
2     N        -0.439  -0.377  -0.362  -0.606  -0.517  -0.514  -0.605  -0.529  -0.490
3     W        -1.574  -1.546  -1.501  -1.350  -1.381  -1.235  -1.135  -1.101  -1.018
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     K        -0.354  -0.281  -0.322  -0.038   0.085   0.025  -0.500  -0.399  -0.437
9     S        -1.267  -1.245  -1.197  -0.887  -0.862  -0.777  -1.018  -0.988  -0.908
10    Y        -0.883  -0.823  -0.818  -1.030  -0.976  -0.884  -0.846  -0.779  -0.739
11    V        -1.651  -1.628  -1.545  -1.581  -1.509  -1.417  -1.191  -1.160  -1.050
12    F        -1.651  -1.628  -1.545  -1.426  -1.365  -1.258  -1.191  -1.160  -1.050
13    P         0.578   0.466   0.386   0.733   0.565   0.428   0.538   0.359   0.208
14    G        -1.267  -1.220  -1.190  -1.118  -1.053  -0.991  -1.018  -0.963  -0.902
15    G        -0.354  -0.415  -0.361  -0.605  -0.685  -0.598  -0.500  -0.560  -0.485
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    H        -0.439  -0.356  -0.361  -0.119   0.000   0.025  -0.605  -0.499  -0.489
31    P         0.376   0.352   0.300   0.261   0.136   0.071   0.189   0.113   0.050
32    P         1.391   1.477   1.273   1.487   1.614   1.281   1.513   1.651   1.257
33    A         0.040  -0.065  -0.174   0.166  -0.025  -0.239   0.057  -0.090  -0.232
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    A        -0.461  -0.485  -0.402  -0.386  -0.390  -0.272  -0.610  -0.638  -0.529
37    L         0.695   0.534   0.460   0.415   0.189   0.073   0.719   0.465   0.328
38    T         0.040  -0.027  -0.167   0.208   0.095  -0.121   0.057  -0.039  -0.223
39    T         0.233   0.255   0.265  -0.016   0.023   0.006  -0.076  -0.039  -0.021
40    G         0.695   0.534   0.460   0.806   0.578   0.424   0.719   0.465   0.328
41    L         1.031   0.952   1.009   0.526   0.380   0.445   0.851   0.670   0.714
42    V        -1.238  -1.223  -1.172  -1.415  -1.376  -1.329  -1.002  -0.978  -0.891
43    V         0.778   0.809   0.919   0.446   0.482   0.655   0.322   0.364   0.516
44    F         1.031   0.952   1.009   0.801   0.607   0.635   0.851   0.670   0.714
45    L         0.233   0.156   0.246  -0.295  -0.379  -0.246  -0.076  -0.165  -0.047
46    T        -0.230  -0.329  -0.294  -0.145  -0.255  -0.199  -0.340  -0.447  -0.402
47    A        -0.775  -0.698  -0.762  -0.776  -0.659  -0.771  -0.737  -0.656  -0.685
48    I         1.031   1.096   1.042   0.526   0.628   0.503   0.851   0.961   0.784
49    Y        -1.111  -1.133  -1.135  -1.004  -1.049  -1.054  -0.870  -0.885  -0.852
50    L        -0.230  -0.246  -0.268  -0.663  -0.680  -0.712  -0.340  -0.352  -0.369
51    L        -0.439  -0.489  -0.381  -0.867  -0.939  -0.803  -0.605  -0.645  -0.514
52    S        -0.775  -0.724  -0.772  -0.632  -0.587  -0.574  -0.737  -0.690  -0.696
53    F        -1.574  -1.561  -1.505  -1.331  -1.314  -1.249  -1.135  -1.113  -1.021
54    I        -1.238  -1.163  -1.179  -1.366  -1.222  -1.213  -1.002  -0.923  -0.896
55    F        -1.238  -1.176  -1.168  -1.040  -0.938  -0.927  -1.002  -0.938  -0.888
56    A        -1.574  -1.540  -1.502  -1.218  -1.177  -1.108  -1.135  -1.096  -1.019
57    -        -1.267  -1.227  -1.189  -0.757  -0.712  -0.630  -1.018  -0.971  -0.901
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    L        -1.238  -1.258  -1.182  -1.621  -1.634  -1.525  -1.002  -1.006  -0.899
60    R        -1.574  -1.546  -1.501  -1.274  -1.294  -1.171  -1.135  -1.101  -1.018
61    E        -1.111  -1.151  -1.137  -0.622  -0.705  -0.646  -0.870  -0.902  -0.854
62    D        -0.902  -0.845  -0.826  -0.467  -0.379  -0.335  -0.870  -0.805  -0.750
63    L        -0.230  -0.313  -0.275  -0.683  -0.795  -0.745  -0.340  -0.424  -0.381
64    S        -1.574  -1.583  -1.508  -1.631  -1.627  -1.544  -1.135  -1.129  -1.024
65    L         2.122   2.163   2.282   1.731   1.795   1.967   2.440   2.504   2.707
66    A        -1.267  -1.259  -1.212  -0.945  -0.937  -0.858  -1.018  -1.000  -0.921
67    P         1.327   1.328   1.215   1.454   1.460   1.285   1.402   1.396   1.141
68    E        -0.883  -0.850  -0.813  -0.521  -0.462  -0.399  -0.846  -0.802  -0.736
69    S         0.175   0.128   0.214   0.046   0.000   0.138  -0.154  -0.203  -0.089
70    L         0.376   0.385   0.324  -0.064  -0.039  -0.145   0.189   0.215   0.095
71    F        -0.566  -0.685  -0.710  -0.474  -0.636  -0.734  -0.473  -0.607  -0.617
72    K        -0.775  -0.752  -0.764  -0.369  -0.331  -0.332  -0.737  -0.698  -0.687
73    L        -0.775  -0.816  -0.765  -0.980  -0.992  -0.959  -0.737  -0.767  -0.687
74    Q        -0.775  -0.802  -0.767  -0.316  -0.352  -0.285  -0.737  -0.758  -0.691
75    M         1.391   1.496   1.281   1.115   1.251   1.006   1.513   1.682   1.272
76    S        -0.230  -0.181  -0.276  -0.016   0.034  -0.096  -0.340  -0.309  -0.385
77    R         0.040   0.005  -0.150   0.511   0.466   0.246   0.057   0.003  -0.199
78    L         0.839   0.924   0.968   0.337   0.513   0.506   0.454   0.612   0.624
79    S         0.695   0.534   0.460   0.826   0.593   0.498   0.719   0.465   0.328
80    L         0.106   0.080   0.154  -0.483  -0.509  -0.405  -0.208  -0.256  -0.164
81    Y         1.391   1.367   1.262   1.657   1.635   1.481   1.513   1.466   1.235
82    P         0.040  -0.006  -0.163   0.161   0.093  -0.215   0.057  -0.011  -0.217
83    L         0.695   0.534   0.460   0.409   0.188   0.061   0.719   0.465   0.328
84    I        -1.238  -1.232  -1.183  -1.306  -1.376  -1.221  -1.002  -0.986  -0.899
85    H         2.122   2.163   2.282   2.420   2.481   2.671   2.440   2.504   2.707
86    L         0.040   0.109  -0.147  -0.163  -0.063  -0.404   0.057   0.155  -0.195
87    S        -0.230  -0.197  -0.280  -0.200  -0.155  -0.264  -0.340  -0.301  -0.390
88    L        -1.111  -1.140  -1.137  -0.929  -0.937  -0.962  -0.870  -0.892  -0.854
89    P        -0.230  -0.160  -0.254  -0.458  -0.391  -0.535  -0.340  -0.267  -0.357
90    H         2.122   2.163   2.282   2.420   2.481   2.671   2.440   2.504   2.707
91    L        -0.230  -0.329  -0.294  -0.505  -0.642  -0.565  -0.340  -0.447  -0.402
92    L        -0.439  -0.417  -0.375  -0.978  -0.936  -0.861  -0.605  -0.583  -0.508
93    F         0.233   0.266   0.257  -0.150  -0.108  -0.096  -0.076  -0.033  -0.033
94    N         2.122   2.163   2.282   2.347   2.415   2.596   2.440   2.504   2.707
95    V        -0.775  -0.814  -0.775  -0.923  -1.014  -0.966  -0.737  -0.771  -0.699
96    L        -0.230  -0.106  -0.238  -0.459  -0.214  -0.480  -0.340  -0.164  -0.328
97    A        -0.230  -0.200  -0.272  -0.212  -0.197  -0.294  -0.340  -0.315  -0.380
98    I        -0.230  -0.163  -0.259  -0.686  -0.573  -0.722  -0.340  -0.236  -0.355
99    W        -1.574  -1.576  -1.505  -1.429  -1.508  -1.316  -1.135  -1.124  -1.021
100   A        -0.775  -0.640  -0.742  -0.756  -0.535  -0.701  -0.737  -0.579  -0.664
101   P        -0.566  -0.662  -0.711  -0.394  -0.575  -0.658  -0.473  -0.583  -0.618
102   L         0.040  -0.027  -0.167  -0.174  -0.245  -0.451   0.057  -0.039  -0.223
103   N        -0.902  -0.874  -0.830  -0.817  -0.785  -0.699  -0.870  -0.830  -0.753
104   L        -1.574  -1.484  -1.493  -1.190  -1.008  -1.069  -1.135  -1.047  -1.012
105   F         2.122   2.163   2.282   2.132   2.193   2.377   2.440   2.504   2.707
106   E         2.122   2.163   2.282   2.352   2.421   2.601   2.440   2.504   2.707
107   E        -1.238  -1.258  -1.188  -0.811  -0.808  -0.718  -1.002  -1.006  -0.904
108   T        -1.238  -1.283  -1.189  -1.036  -1.056  -0.917  -1.002  -1.024  -0.904
109   H         0.233   0.162   0.249   0.439   0.368   0.502  -0.076  -0.154  -0.042
110   G         2.122   2.163   2.282   2.159   2.221   2.405   2.440   2.504   2.707
111   T         2.122   2.163   2.282   2.168   2.230   2.413   2.440   2.504   2.707
112   V         0.023   0.072   0.141  -0.569  -0.525  -0.411  -0.340  -0.272  -0.186
113   Y        -1.238  -1.272  -1.188  -0.866  -0.918  -0.781  -1.002  -1.016  -0.903
114   T         0.695   0.534   0.460   0.907   0.704   0.599   0.719   0.465   0.328
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   G         0.695   0.534   0.460   0.788   0.532   0.392   0.719   0.465   0.328
117   V         0.695   0.660   0.469   0.774   0.718   0.381   0.719   0.664   0.344
118   F        -0.439  -0.377  -0.373  -0.613  -0.515  -0.519  -0.605  -0.528  -0.505
119   L         0.695   0.534   0.460   0.407   0.186   0.059   0.719   0.465   0.328
120   N         0.695   0.534   0.460   1.027   0.798   0.670   0.719   0.465   0.328
121   L        -0.230  -0.245  -0.293  -0.643  -0.659  -0.716  -0.340  -0.380  -0.407
122   S        -0.230  -0.306  -0.272  -0.645  -0.720  -0.682  -0.340  -0.413  -0.373
123   A         1.031   0.986   1.011   1.024   0.929   0.937   0.851   0.740   0.719
124   L         0.376   0.311   0.303   0.187   0.055  -0.015   0.189   0.084   0.053
125   F        -0.313  -0.270  -0.294  -0.465  -0.411  -0.422  -0.473  -0.420  -0.417
126   A         0.106   0.080   0.153  -0.013  -0.073   0.028  -0.208  -0.255  -0.165
127   G         0.839   0.885   0.944   0.636   0.708   0.778   0.454   0.528   0.573
128   I         0.839   0.870   0.946   0.337   0.374   0.439   0.454   0.497   0.575
129   L        -0.902  -0.906  -0.830  -0.864  -0.836  -0.766  -0.870  -0.861  -0.753
130   Y         0.040  -0.029  -0.158   0.468   0.387   0.211   0.057  -0.041  -0.210
131   C         0.695   0.534   0.460   1.126   0.867   0.721   0.719   0.465   0.328
132   L        -0.313  -0.285  -0.308  -0.782  -0.722  -0.751  -0.473  -0.434  -0.431
133   L         0.376   0.473   0.331   0.177   0.340   0.041   0.189   0.335   0.102
134   G        -0.230  -0.334  -0.294  -0.186  -0.311  -0.262  -0.340  -0.454  -0.405
135   K        -1.238  -1.247  -1.178  -1.000  -0.990  -0.926  -1.002  -0.997  -0.896
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   L        -0.230  -0.331  -0.296  -0.688  -0.836  -0.777  -0.340  -0.461  -0.410
138   L         1.031   1.067   1.036   0.532   0.589   0.501   0.851   0.904   0.771
139   Y        -0.775  -0.825  -0.780  -0.544  -0.586  -0.529  -0.737  -0.778  -0.703
140   P         0.040  -0.055  -0.167   0.227   0.108  -0.115   0.057  -0.077  -0.223
141   E         0.106   0.124   0.178   0.270   0.310   0.384  -0.208  -0.189  -0.127
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   A        -0.230  -0.206  -0.275  -0.180  -0.161  -0.237  -0.340  -0.322  -0.384
144   L        -1.574  -1.570  -1.504  -1.456  -1.453  -1.349  -1.135  -1.120  -1.021
145   V         1.031   1.001   1.020   0.952   0.883   0.877   0.851   0.771   0.738
146   A        -0.775  -0.754  -0.770  -0.795  -0.750  -0.796  -0.737  -0.701  -0.690
147   G         2.122   2.163   2.282   2.159   2.221   2.405   2.440   2.504   2.707
148   A         0.233   0.238   0.251  -0.162  -0.190  -0.163  -0.076  -0.072  -0.041
149   S         2.122   2.163   2.282   2.113   2.167   2.357   2.440   2.504   2.707
150   G         0.695   0.660   0.469   0.906   0.872   0.619   0.719   0.664   0.344
151   W         0.695   0.785   0.487   1.138   1.265   0.825   0.719   0.856   0.372
152   C        -0.775  -0.722  -0.754  -0.673  -0.621  -0.622  -0.737  -0.684  -0.678
153   F         2.122   2.163   2.282   2.132   2.193   2.377   2.440   2.504   2.707
154   T        -0.439  -0.473  -0.366  -0.840  -0.888  -0.745  -0.605  -0.625  -0.495
155   L         0.839   0.875   0.942   0.352   0.414   0.443   0.454   0.508   0.568
156   F        -0.439  -0.402  -0.380  -0.607  -0.581  -0.571  -0.605  -0.567  -0.513
157   A        -0.313  -0.214  -0.295  -0.433  -0.310  -0.384  -0.473  -0.365  -0.417
158   Y         0.040  -0.067  -0.166   0.427   0.279   0.135   0.057  -0.092  -0.221
159   Y        -1.574  -1.565  -1.519  -1.211  -1.193  -1.150  -1.135  -1.116  -1.031
160   S         0.376   0.412   0.318   0.524   0.565   0.449   0.189   0.217   0.078
161   F        -0.439  -0.379  -0.367  -0.538  -0.463  -0.432  -0.605  -0.536  -0.497
162   K         0.106   0.064   0.148   0.307   0.241   0.369  -0.208  -0.277  -0.175
163   E         0.695   0.534   0.460   1.033   0.806   0.676   0.719   0.465   0.328
164   S         0.040  -0.067  -0.166   0.255   0.095  -0.010   0.057  -0.092  -0.221
165   Q        -0.775  -0.717  -0.762  -0.334  -0.261  -0.292  -0.737  -0.672  -0.686
166   I        -1.267  -1.211  -1.194  -1.368  -1.246  -1.275  -1.018  -0.955  -0.906
167   R        -0.738  -0.765  -0.767  -0.298  -0.329  -0.335  -0.673  -0.698  -0.680
168   P         0.695   0.631   0.477   0.965   0.888   0.697   0.719   0.609   0.357
169   R        -1.574  -1.587  -1.520  -1.440  -1.539  -1.411  -1.135  -1.132  -1.033
170   T        -1.238  -1.192  -1.171  -1.312  -1.233  -1.214  -1.002  -0.951  -0.890
171   R        -1.910  -1.881  -1.808  -1.238  -1.237  -1.066  -1.267  -1.232  -1.128
172   I        -0.439  -0.475  -0.375  -0.863  -0.910  -0.793  -0.605  -0.628  -0.505
173   F        -0.230  -0.181  -0.269  -0.278  -0.207  -0.343  -0.340  -0.275  -0.375
174   R        -1.267  -1.275  -1.214  -0.840  -0.846  -0.756  -1.018  -1.015  -0.923
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   D        -0.775  -0.792  -0.771  -0.653  -0.722  -0.639  -0.737  -0.744  -0.692
181   Y        -1.238  -1.178  -1.168  -1.201  -1.126  -1.103  -1.002  -0.940  -0.888
182   S         0.040   0.020  -0.159   0.243   0.218  -0.016   0.057   0.033  -0.211
183   I         0.040   0.111  -0.136   0.073   0.175  -0.249   0.057   0.157  -0.180
184   P         1.391   1.444   1.273   1.569   1.645   1.434   1.513   1.596   1.257
185   T         1.391   1.274   1.262   1.517   1.365   1.352   1.513   1.299   1.235
186   L        -0.230  -0.290  -0.293  -0.387  -0.439  -0.376  -0.340  -0.419  -0.407
187   Y        -0.566  -0.654  -0.706  -0.289  -0.411  -0.554  -0.473  -0.574  -0.613
188   T        -0.775  -0.748  -0.768  -0.931  -0.902  -0.965  -0.737  -0.707  -0.692
189   P         2.122   2.163   2.282   2.205   2.268   2.452   2.440   2.504   2.707
190   L        -0.566  -0.535  -0.441  -1.081  -1.037  -0.912  -0.737  -0.696  -0.576
191   V        -0.313  -0.289  -0.297  -0.534  -0.521  -0.528  -0.473  -0.436  -0.420
192   L        -0.439  -0.413  -0.376  -0.862  -0.787  -0.730  -0.605  -0.573  -0.509
193   L         0.695   0.686   0.479   0.424   0.419   0.120   0.719   0.703   0.360
194   V        -0.313  -0.225  -0.293  -0.557  -0.430  -0.548  -0.473  -0.375  -0.415
195   A         0.040   0.048  -0.142   0.274   0.295   0.027   0.057   0.058  -0.188
196   I        -0.230  -0.140  -0.257  -0.184  -0.050  -0.206  -0.340  -0.217  -0.358
197   A         0.376   0.310   0.321   0.512   0.419   0.440   0.189   0.105   0.090
198   V        -0.230  -0.169  -0.252  -0.370  -0.258  -0.438  -0.340  -0.246  -0.351
199   V         0.839   0.904   0.958   0.221   0.324   0.389   0.454   0.569   0.602
200   I        -0.775  -0.824  -0.766  -0.946  -1.050  -0.963  -0.737  -0.775  -0.689
201   P         1.391   1.490   1.276   1.542   1.677   1.389   1.513   1.672   1.263
202   G        -0.313  -0.332  -0.300  -0.327  -0.344  -0.252  -0.473  -0.485  -0.422
203   S         1.391   1.274   1.262   1.462   1.303   1.297   1.513   1.299   1.235
204   S         2.122   2.163   2.282   2.113   2.167   2.357   2.440   2.504   2.707
205   F         1.031   1.102   1.041   0.801   0.927   0.717   0.851   0.974   0.783
206   W        -0.566  -0.535  -0.444  -0.847  -0.828  -0.674  -0.737  -0.695  -0.579
207   G         2.122   2.163   2.282   2.159   2.221   2.405   2.440   2.504   2.707
208   H         2.122   2.163   2.282   2.420   2.481   2.671   2.440   2.504   2.707
209   F        -0.230  -0.153  -0.272  -0.630  -0.525  -0.673  -0.340  -0.261  -0.379
210   F        -0.775  -0.798  -0.759  -0.899  -0.947  -0.917  -0.737  -0.748  -0.681
211   G         2.122   2.163   2.282   2.159   2.221   2.405   2.440   2.504   2.707
212   L        -0.230  -0.246  -0.268  -0.585  -0.608  -0.592  -0.340  -0.352  -0.369
213   C        -1.238  -1.221  -1.174  -1.458  -1.460  -1.336  -1.002  -0.977  -0.892
214   V        -1.111  -1.118  -1.133  -1.027  -0.999  -1.090  -0.870  -0.870  -0.850
215   G         2.122   2.163   2.282   2.159   2.221   2.405   2.440   2.504   2.707
216   Y         1.391   1.415   1.266   1.703   1.747   1.575   1.513   1.548   1.243
217   A        -1.574  -1.565  -1.519  -1.583  -1.492  -1.424  -1.135  -1.116  -1.031
218   I        -0.775  -0.817  -0.778  -0.787  -0.851  -0.814  -0.737  -0.769  -0.698
219   G        -0.230  -0.288  -0.289  -0.220  -0.302  -0.314  -0.340  -0.403  -0.399
220   Y         0.233   0.177   0.266  -0.194  -0.267  -0.129  -0.076  -0.127  -0.016
221   K         0.376   0.335   0.333   0.484   0.458   0.459   0.189   0.149   0.111
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   W         0.778   0.808   0.919   0.808   0.853   1.023   0.322   0.361   0.516
231   F        -0.902  -0.907  -0.833  -1.306  -1.331  -1.210  -0.870  -0.861  -0.756
232   N        -0.902  -0.910  -0.830  -0.507  -0.491  -0.370  -0.870  -0.864  -0.753
233   K        -0.775  -0.810  -0.773  -0.578  -0.625  -0.581  -0.737  -0.766  -0.696
234   I         0.376   0.335   0.333  -0.093  -0.133  -0.162   0.189   0.149   0.111
235   T        -0.902  -0.948  -0.837  -0.817  -0.843  -0.690  -0.870  -0.893  -0.759
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   P         2.122   2.163   2.282   2.205   2.268   2.452   2.440   2.504   2.707
238   P         1.327   1.328   1.215   1.454   1.460   1.285   1.402   1.396   1.141
239   G        -0.738  -0.709  -0.745  -0.776  -0.708  -0.821  -0.673  -0.636  -0.656
240   W         0.175   0.218   0.223   0.346   0.414   0.427  -0.154  -0.098  -0.078
241   I         0.030   0.058   0.151  -0.211  -0.170  -0.030  -0.327  -0.288  -0.170
242   I         0.269   0.233   0.243  -0.060  -0.165  -0.189   0.019  -0.044  -0.040
243   T        -0.883  -0.882  -0.818  -1.030  -1.015  -0.884  -0.846  -0.834  -0.740
244   K        -0.775  -0.834  -0.791  -0.546  -0.654  -0.573  -0.737  -0.788  -0.714
245   I         1.391   1.274   1.262   1.452   1.285   1.276   1.513   1.299   1.235
246   E         1.391   1.274   1.262   1.730   1.597   1.592   1.513   1.299   1.235
247   K        -1.574  -1.544  -1.503  -1.131  -1.116  -1.015  -1.135  -1.100  -1.020
248   S         0.376   0.408   0.315   0.655   0.688   0.561   0.189   0.208   0.073
249   L        -0.115  -0.064  -0.230  -0.471  -0.401  -0.647  -0.154  -0.082  -0.306
250   D        -0.354  -0.387  -0.355  -0.108  -0.159  -0.101  -0.500  -0.535  -0.481
251   G        -1.267  -1.268  -1.209  -1.323  -1.377  -1.261  -1.018  -1.008  -0.918
252   L         0.578   0.612   0.417   0.236   0.283  -0.007   0.538   0.588   0.259
253   I         1.327   1.236   1.212   1.393   1.265   1.222   1.402   1.229   1.136
254   R         0.269   0.241   0.250   0.494   0.458   0.485   0.019  -0.029  -0.029
255   L         0.440   0.447   0.323   0.044   0.054  -0.146   0.322   0.331   0.107
256   I         0.888   0.909   0.974   0.475   0.493   0.535   0.557   0.580   0.639
257   P         0.440   0.447   0.323   0.623   0.641   0.463   0.322   0.331   0.107
258   W        -0.456  -0.423  -0.388  -0.716  -0.683  -0.621  -0.620  -0.575  -0.517
259   G        -0.287  -0.318  -0.343  -0.453  -0.516  -0.643  -0.384  -0.421  -0.455
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   I         0.233   0.250   0.266  -0.050  -0.012  -0.024  -0.076  -0.028  -0.012
262   K        -0.230  -0.214  -0.280  -0.032  -0.002  -0.126  -0.340  -0.315  -0.388
263   Y        -0.313  -0.400  -0.307  -0.211  -0.299  -0.153  -0.473  -0.553  -0.431
264   Y         2.122   2.163   2.282   2.320   2.385   2.569   2.440   2.504   2.707
265   R        -0.230  -0.329  -0.294   0.122   0.000   0.046  -0.340  -0.447  -0.402
266   D         0.233   0.289   0.262   0.252   0.295   0.316  -0.076  -0.019  -0.028
267   E        -0.230  -0.272  -0.282  -0.074  -0.145  -0.181  -0.340  -0.392  -0.393
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -         0.279   0.399   0.307   0.554   0.751   0.580   0.067   0.255   0.080
272   -         0.817   0.861   0.947   0.776   0.854   0.964   0.406   0.478   0.578
273   -         0.279   0.226   0.259   0.405   0.282   0.310   0.067  -0.022   0.003
274   -        -0.461  -0.488  -0.406  -0.594  -0.653  -0.535  -0.610  -0.639  -0.535
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   D        -0.456  -0.502  -0.387  -0.283  -0.352  -0.183  -0.620  -0.660  -0.517
280   I         0.161   0.171   0.215  -0.055  -0.047   0.021  -0.149  -0.133  -0.082
281   D         0.076   0.040   0.166   0.183   0.122   0.316  -0.271  -0.317  -0.152
282   R         0.279   0.249   0.256   0.511   0.466   0.452   0.067   0.004  -0.001
283   T        -0.287  -0.257  -0.293  -0.261  -0.242  -0.264  -0.384  -0.353  -0.390
284   K        -0.354  -0.232  -0.321  -0.659  -0.508  -0.556  -0.500  -0.345  -0.435
285   D        -0.354  -0.234  -0.314  -0.362  -0.200  -0.268  -0.500  -0.345  -0.430
286   Y         0.578   0.427   0.386   0.837   0.606   0.527   0.538   0.292   0.208
287   E        -1.651  -1.613  -1.545  -1.285  -1.263  -1.114  -1.191  -1.149  -1.050
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   P         0.161   0.156   0.203   0.042   0.044   0.111  -0.149  -0.150  -0.096
291   L         0.161   0.187   0.203  -0.433  -0.397  -0.360  -0.149  -0.118  -0.099
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   M         0.269   0.359   0.277  -0.190  -0.067  -0.147   0.019   0.152   0.015
294   S        -0.499  -0.473  -0.404  -0.628  -0.583  -0.469  -0.673  -0.636  -0.539
295   T        -0.738  -0.676  -0.746  -0.634  -0.534  -0.645  -0.673  -0.594  -0.657
296   E        -0.499  -0.521  -0.410  -0.257  -0.286  -0.117  -0.673  -0.682  -0.545
297   T        -1.267  -1.177  -1.189  -1.142  -0.996  -1.024  -1.018  -0.922  -0.901
298   P        -1.267  -1.259  -1.212  -0.956  -0.949  -0.875  -1.018  -1.000  -0.921
299   L         0.175   0.208   0.225  -0.308  -0.228  -0.168  -0.154  -0.105  -0.074
300   P        -0.354  -0.368  -0.355  -0.388  -0.419  -0.400  -0.500  -0.515  -0.480
301   L        -0.287  -0.334  -0.324  -0.564  -0.611  -0.560  -0.384  -0.444  -0.430
302   H         0.161   0.239   0.232   0.223   0.333   0.346  -0.149  -0.034  -0.050
303   N         0.161   0.128   0.208   0.292   0.245   0.362  -0.149  -0.190  -0.092
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   D        -0.287  -0.284  -0.313  -0.194  -0.199  -0.235  -0.384  -0.377  -0.416
315   N        -0.904  -0.892  -0.833  -0.774  -0.763  -0.654  -0.855  -0.833  -0.750
316   S        -0.456  -0.461  -0.388  -0.636  -0.644  -0.534  -0.620  -0.616  -0.518
317   -        -0.461  -0.437  -0.402  -0.299  -0.257  -0.190  -0.610  -0.576  -0.529
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   -        -0.287  -0.197  -0.267  -0.267  -0.131  -0.237  -0.384  -0.260  -0.356
321   -        -0.287  -0.229  -0.280  -0.329  -0.238  -0.333  -0.384  -0.303  -0.373
322   -         1.248   1.255   1.193   1.260   1.272   1.166   1.263   1.264   1.097
323   -        -0.904  -0.833  -0.819  -0.835  -0.723  -0.704  -0.855  -0.770  -0.735
324   -         2.122   2.163   2.282   2.180   2.241   2.426   2.440   2.504   2.707
325   -        -0.461  -0.480  -0.406  -0.264  -0.282  -0.185  -0.610  -0.632  -0.535
326   G         1.391   1.444   1.273   1.501   1.578   1.347   1.513   1.596   1.257
327   T        -0.439  -0.387  -0.369  -0.220  -0.161  -0.107  -0.605  -0.546  -0.501
328   V         0.376   0.305   0.285   0.441   0.329   0.310   0.189   0.054   0.025
329   L         2.122   2.163   2.282   1.731   1.795   1.967   2.440   2.504   2.707
330   G         2.122   2.163   2.282   2.159   2.221   2.405   2.440   2.504   2.707
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   T         1.152   1.202   1.122   1.179   1.256   1.116   1.084   1.167   0.953
336   A        -1.574  -1.587  -1.520  -1.258  -1.284  -1.161  -1.135  -1.132  -1.033
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12270
Output conservation file - output/Q12270
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
