1     M         2.336   2.409   2.481   2.585   2.712   2.835   2.695   2.814   2.954
2     K         0.648   0.646   0.715   0.250   0.203   0.321   0.309   0.282   0.384
3     R        -0.048  -0.193  -0.197   0.208  -0.015  -0.033  -0.088  -0.291  -0.301
4     F        -1.006  -1.066  -1.023  -0.834  -0.959  -0.875  -0.883  -0.935  -0.871
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     N        -1.006  -1.066  -1.023  -0.966  -1.007  -0.965  -0.883  -0.935  -0.871
10    V        -1.006  -1.030  -0.996  -1.129  -1.170  -1.122  -0.883  -0.898  -0.842
11    S         0.648   0.646   0.715   0.216   0.189   0.300   0.309   0.282   0.384
12    Y         1.081   1.014   0.966   1.427   1.355   1.293   1.104   0.977   0.874
13    V        -0.048  -0.193  -0.197   0.071  -0.114  -0.104  -0.088  -0.291  -0.301
14    E        -0.048  -0.193  -0.197   0.082  -0.136  -0.137  -0.088  -0.291  -0.301
15    V        -0.310  -0.330  -0.246  -0.682  -0.716  -0.588  -0.486  -0.494  -0.381
16    I        -1.006  -1.066  -1.023  -0.837  -0.898  -0.801  -0.883  -0.935  -0.871
17    K        -1.006  -1.066  -1.023  -0.948  -1.011  -0.944  -0.883  -0.935  -0.871
18    N         0.648   0.671   0.725   0.425   0.462   0.553   0.309   0.330   0.404
19    G        -0.310  -0.320  -0.251  -0.356  -0.378  -0.269  -0.486  -0.479  -0.384
20    E        -1.006  -0.821  -0.961  -0.897  -0.584  -0.822  -0.883  -0.649  -0.802
21    T        -1.006  -0.958  -0.955  -1.082  -0.999  -1.014  -0.883  -0.816  -0.795
22    I        -0.048   0.188  -0.062  -0.271   0.093  -0.304  -0.088   0.261  -0.103
23    S        -0.048  -0.193  -0.197   0.026  -0.157  -0.135  -0.088  -0.291  -0.301
24    S        -0.048  -0.193  -0.197  -0.077  -0.296  -0.285  -0.088  -0.291  -0.301
25    C         0.739   0.725   0.750   1.023   1.006   1.042   0.486   0.438   0.455
26    F         0.739   0.818   0.772   0.818   0.953   0.856   0.486   0.615   0.499
27    Q        -0.420  -0.381  -0.320  -0.502  -0.442  -0.339  -0.618  -0.558  -0.475
28    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    Q        -1.701  -1.660  -1.622  -1.334  -1.216  -1.195  -1.281  -1.222  -1.161
32    K        -1.006  -0.960  -0.953  -0.993  -0.896  -0.914  -0.883  -0.818  -0.793
33    N        -0.048  -0.011  -0.099  -0.081  -0.001  -0.162  -0.088  -0.038  -0.158
34    E        -0.048  -0.015  -0.106  -0.089  -0.044  -0.162  -0.088  -0.043  -0.167
35    N        -0.310  -0.212  -0.237  -0.561  -0.421  -0.438  -0.486  -0.360  -0.372
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    Y         0.926   0.805   0.833   1.093   0.880   0.904   0.831   0.592   0.620
38    G         0.926   0.805   0.833   1.164   0.985   1.036   0.831   0.592   0.620
39    T        -1.142  -1.085  -1.053  -1.234  -1.211  -1.092  -1.033  -0.953  -0.903
40    I        -0.272  -0.281  -0.262  -0.386  -0.414  -0.406  -0.411  -0.427  -0.395
41    T        -0.272  -0.171  -0.211  -0.465  -0.309  -0.365  -0.411  -0.261  -0.321
42    S        -1.142  -1.085  -1.053  -1.437  -1.373  -1.300  -1.033  -0.953  -0.903
43    A        -0.272  -0.281  -0.262  -0.194  -0.269  -0.194  -0.411  -0.427  -0.395
44    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    E        -0.420  -0.381  -0.320  -0.574  -0.528  -0.413  -0.618  -0.559  -0.475
46    Q        -1.006  -1.033  -1.002  -0.771  -0.829  -0.763  -0.883  -0.901  -0.849
47    I        -1.006  -0.914  -0.959  -0.878  -0.730  -0.797  -0.883  -0.766  -0.799
48    T        -1.701  -1.660  -1.622  -1.143  -1.035  -0.998  -1.281  -1.222  -1.161
49    P        -0.310  -0.320  -0.251  -0.352  -0.403  -0.293  -0.486  -0.479  -0.384
50    V        -1.006  -0.821  -0.961  -0.916  -0.613  -0.838  -0.883  -0.649  -0.802
51    I         0.648   0.671   0.725   0.268   0.301   0.371   0.309   0.330   0.404
52    F         0.648   0.646   0.715   0.496   0.460   0.558   0.309   0.282   0.384
53    H         0.926   0.805   0.833   1.137   0.888   0.927   0.831   0.592   0.620
54    N        -1.142  -1.085  -1.053  -1.206  -1.065  -1.062  -1.033  -0.953  -0.903
55    L         0.926   0.805   0.833   0.732   0.518   0.572   0.831   0.592   0.620
56    I        -0.272  -0.264  -0.256  -0.605  -0.626  -0.605  -0.411  -0.405  -0.385
57    M        -0.272  -0.092  -0.205  -0.146   0.166  -0.035  -0.411  -0.146  -0.312
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    D        -0.048  -0.193  -0.197   0.071  -0.161  -0.187  -0.088  -0.291  -0.301
63    M        -0.048  -0.193  -0.197   0.124  -0.146  -0.188  -0.088  -0.291  -0.301
64    V         1.081   1.014   0.966   1.074   0.985   0.911   1.104   0.977   0.874
65    L        -0.048   0.122  -0.066  -0.271  -0.009  -0.311  -0.088   0.164  -0.110
66    P        -1.006  -1.066  -1.023  -0.649  -0.759  -0.691  -0.883  -0.935  -0.871
67    K        -0.048  -0.074  -0.130  -0.014  -0.052  -0.124  -0.088  -0.123  -0.203
68    V        -0.048  -0.193  -0.197  -0.167  -0.419  -0.454  -0.088  -0.291  -0.301
69    V        -0.310  -0.331  -0.247  -0.659  -0.689  -0.563  -0.486  -0.495  -0.382
70    P         1.081   1.175   1.005   1.426   1.590   1.311   1.104   1.259   0.946
71    I        -1.006  -0.958  -0.955  -1.148  -1.048  -1.070  -0.883  -0.816  -0.795
72    K        -1.006  -0.961  -0.955  -1.016  -0.951  -0.922  -0.883  -0.819  -0.795
73    G         0.648   0.646   0.715   0.454   0.386   0.505   0.309   0.282   0.384
74    N        -0.048  -0.193  -0.197  -0.159  -0.410  -0.442  -0.088  -0.291  -0.301
75    K         1.081   1.014   0.966   1.036   0.934   0.853   1.104   0.977   0.874
76    V        -0.048  -0.193  -0.197  -0.008  -0.218  -0.219  -0.088  -0.291  -0.301
77    T        -0.048  -0.193  -0.197  -0.022  -0.285  -0.318  -0.088  -0.291  -0.301
78    K         1.081   1.012   0.968   1.004   0.885   0.805   1.104   0.974   0.877
79    M        -0.048  -0.074  -0.130   0.170   0.114   0.013  -0.088  -0.123  -0.203
80    S         1.081   1.012   0.968   1.047   0.954   0.908   1.104   0.974   0.877
81    M        -1.006  -0.958  -0.955  -0.761  -0.665  -0.677  -0.883  -0.816  -0.795
82    N        -1.006  -0.914  -0.959  -0.747  -0.580  -0.655  -0.883  -0.766  -0.799
83    L         1.081   1.014   0.966   0.969   0.873   0.820   1.104   0.977   0.874
84    I        -0.048  -0.193  -0.197  -0.079  -0.294  -0.310  -0.088  -0.291  -0.301
85    D        -1.006  -1.066  -1.023  -1.003  -1.117  -1.062  -0.883  -0.935  -0.871
86    G        -0.048  -0.193  -0.197   0.204  -0.024  -0.027  -0.088  -0.291  -0.301
87    F        -0.310  -0.320  -0.251  -0.274  -0.287  -0.181  -0.486  -0.479  -0.384
88    D        -0.048  -0.193  -0.197  -0.029  -0.286  -0.336  -0.088  -0.291  -0.301
89    C        -0.048  -0.193  -0.197   0.264   0.007  -0.023  -0.088  -0.291  -0.301
90    F        -1.006  -1.033  -1.002  -0.759  -0.816  -0.761  -0.883  -0.901  -0.849
91    Y         0.648   0.646   0.715   0.680   0.659   0.773   0.309   0.282   0.384
92    S        -1.006  -1.033  -1.002  -0.899  -0.923  -0.894  -0.883  -0.901  -0.849
93    T         1.081   1.014   0.966   1.242   1.150   1.089   1.104   0.977   0.874
94    D        -1.006  -0.821  -0.961  -0.944  -0.687  -0.851  -0.883  -0.649  -0.802
95    D        -0.048  -0.074  -0.130   0.128   0.113   0.009  -0.088  -0.123  -0.203
96    H        -1.006  -0.961  -0.955  -0.813  -0.738  -0.721  -0.883  -0.819  -0.795
97    D         0.739   0.681   0.750   0.750   0.671   0.776   0.486   0.351   0.455
98    P        -0.420  -0.354  -0.320  -0.390  -0.321  -0.224  -0.618  -0.521  -0.475
99    K        -1.006  -1.033  -1.002  -1.127  -1.176  -1.129  -0.883  -0.901  -0.849
100   T        -1.006  -1.066  -1.023  -1.054  -1.176  -1.121  -0.883  -0.935  -0.871
101   V         0.648   0.646   0.715   0.377   0.371   0.483   0.309   0.282   0.384
102   Y        -1.006  -1.033  -1.002  -1.046  -1.085  -1.005  -0.883  -0.901  -0.849
103   V         0.648   0.671   0.725   0.275   0.305   0.375   0.309   0.330   0.404
104   C        -0.048  -0.193  -0.197   0.276   0.019  -0.004  -0.088  -0.291  -0.301
105   F         0.648   0.646   0.715   0.483   0.446   0.541   0.309   0.282   0.384
106   T        -0.048  -0.074  -0.130   0.086   0.052  -0.043  -0.088  -0.123  -0.203
107   L        -1.006  -0.914  -0.959  -0.951  -0.789  -0.862  -0.883  -0.766  -0.799
108   V         0.648   0.689   0.730   0.373   0.435   0.484   0.309   0.365   0.415
109   D        -1.006  -1.066  -1.023  -0.861  -0.945  -0.884  -0.883  -0.935  -0.871
110   M        -1.701  -1.660  -1.622  -1.371  -1.258  -1.233  -1.281  -1.222  -1.161
111   P        -0.048  -0.193  -0.197   0.308   0.074   0.043  -0.088  -0.291  -0.301
112   K         1.081   1.012   0.968   1.101   1.011   0.955   1.104   0.974   0.877
113   I        -1.006  -1.066  -1.023  -1.026  -1.109  -1.032  -0.883  -0.935  -0.871
114   L         1.081   1.012   0.968   0.972   0.869   0.827   1.104   0.974   0.877
115   P         1.081   1.014   0.966   1.426   1.335   1.241   1.104   0.977   0.874
116   I        -0.310  -0.321  -0.245  -0.639  -0.634  -0.516  -0.486  -0.480  -0.375
117   R        -0.048  -0.193  -0.197   0.069  -0.195  -0.240  -0.088  -0.291  -0.301
118   I        -1.006  -0.961  -0.955  -1.064  -0.951  -0.981  -0.883  -0.819  -0.795
119   L         2.336   2.409   2.481   2.142   2.242   2.380   2.695   2.814   2.954
120   S        -0.048  -0.193  -0.197  -0.245  -0.518  -0.534  -0.088  -0.291  -0.301
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   G         1.081   1.253   1.025   1.189   1.439   1.130   1.104   1.389   0.983
129   L         1.081   1.014   0.966   0.986   0.893   0.846   1.104   0.977   0.874
130   Q        -0.048  -0.015  -0.106  -0.031   0.005  -0.108  -0.088  -0.043  -0.167
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   E        -0.272  -0.224  -0.211  -0.261  -0.208  -0.158  -0.411  -0.341  -0.321
133   Y        -0.272  -0.111  -0.218  -0.192   0.094  -0.105  -0.411  -0.172  -0.331
134   E        -0.272  -0.330  -0.285  -0.362  -0.461  -0.405  -0.411  -0.487  -0.427
135   S        -1.006  -0.958  -0.955  -0.856  -0.799  -0.748  -0.883  -0.816  -0.795
136   N        -1.006  -0.958  -0.955  -0.961  -0.888  -0.868  -0.883  -0.816  -0.795
137   A        -1.701  -1.660  -1.622  -1.515  -1.440  -1.381  -1.281  -1.222  -1.161
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   T        -0.310  -0.194  -0.252  -0.610  -0.445  -0.507  -0.486  -0.328  -0.388
141   N        -1.006  -1.033  -1.002  -1.088  -1.156  -1.121  -0.883  -0.901  -0.849
142   E        -1.006  -1.030  -0.996  -1.018  -1.063  -1.012  -0.883  -0.898  -0.842
143   L        -1.142  -1.085  -1.053  -1.199  -1.079  -1.055  -1.033  -0.954  -0.903
144   L         0.926   0.804   0.833   0.689   0.463   0.503   0.831   0.589   0.620
145   S        -0.310  -0.227  -0.253  -0.494  -0.328  -0.373  -0.486  -0.362  -0.387
146   S        -0.048  -0.010  -0.105  -0.045  -0.002  -0.106  -0.088  -0.035  -0.167
147   H        -1.701  -1.660  -1.622  -1.357  -1.334  -1.218  -1.281  -1.222  -1.161
148   V        -0.310  -0.227  -0.253  -0.675  -0.543  -0.586  -0.486  -0.362  -0.387
149   G        -0.310  -0.227  -0.253  -0.390  -0.282  -0.298  -0.486  -0.362  -0.387
150   Q        -1.006  -1.033  -1.002  -0.899  -0.919  -0.861  -0.883  -0.901  -0.849
151   I        -1.006  -1.066  -1.023  -1.121  -1.239  -1.149  -0.883  -0.935  -0.871
152   L         2.336   2.409   2.481   2.142   2.242   2.380   2.695   2.814   2.954
153   D        -0.048  -0.193  -0.197   0.091  -0.129  -0.157  -0.088  -0.291  -0.301
154   S        -1.006  -0.914  -0.959  -1.161  -1.001  -1.093  -0.883  -0.766  -0.799
155   F         2.336   2.409   2.481   2.510   2.636   2.757   2.695   2.814   2.954
156   H        -0.048  -0.193  -0.197   0.256   0.003  -0.027  -0.088  -0.291  -0.301
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   E        -0.310  -0.331  -0.247  -0.462  -0.472  -0.348  -0.486  -0.495  -0.382
161   E         1.081   1.014   0.966   1.189   1.101   1.037   1.104   0.977   0.874
162   L        -0.048  -0.193  -0.197  -0.165  -0.382  -0.382  -0.088  -0.291  -0.301
163   V        -0.310  -0.258  -0.235  -0.682  -0.593  -0.569  -0.486  -0.411  -0.369
164   E        -1.701  -1.660  -1.622  -1.639  -1.589  -1.508  -1.281  -1.222  -1.161
165   Y         1.081   1.012   0.968   1.305   1.196   1.106   1.104   0.974   0.877
166   R        -1.006  -1.030  -0.996  -0.914  -0.964  -0.922  -0.883  -0.898  -0.842
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   N         1.081   1.175   1.005   1.074   1.228   0.974   1.104   1.259   0.946
174   Q        -0.048  -0.075  -0.136   0.095   0.030  -0.070  -0.088  -0.125  -0.211
175   T        -1.142  -1.103  -1.053  -1.028  -0.931  -0.879  -1.033  -0.974  -0.903
176   L        -1.142  -1.103  -1.053  -1.369  -1.322  -1.231  -1.033  -0.974  -0.903
177   N        -0.272  -0.111  -0.218  -0.267   0.044  -0.198  -0.411  -0.172  -0.331
178   S        -0.420  -0.363  -0.320  -0.912  -0.839  -0.761  -0.618  -0.533  -0.475
179   S        -0.420  -0.363  -0.320  -0.512  -0.385  -0.350  -0.618  -0.533  -0.475
180   G         2.336   2.409   2.481   2.507   2.626   2.754   2.695   2.814   2.954
181   N         0.739   0.691   0.750   0.320   0.180   0.283   0.486   0.371   0.455
182   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   G         2.336   2.409   2.481   2.530   2.649   2.778   2.695   2.814   2.954
190   Q        -0.272  -0.290  -0.256  -0.132  -0.151  -0.097  -0.411  -0.430  -0.385
191   N        -1.142  -1.118  -1.053  -0.975  -0.909  -0.825  -1.033  -0.988  -0.903
192   T        -0.272  -0.290  -0.256  -0.276  -0.304  -0.254  -0.411  -0.430  -0.385
193   I        -0.272  -0.250  -0.215  -0.227  -0.185  -0.143  -0.411  -0.375  -0.327
194   S        -1.142  -1.118  -1.053  -1.191  -1.151  -1.048  -1.033  -0.988  -0.903
195   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   A        -1.701  -1.660  -1.622  -1.780  -1.764  -1.653  -1.281  -1.222  -1.161
203   T         0.648   0.748   0.775   0.590   0.760   0.804   0.309   0.482   0.505
204   E        -0.048  -0.193  -0.197   0.030  -0.197  -0.214  -0.088  -0.291  -0.301
205   D        -0.310  -0.321  -0.245  -0.453  -0.472  -0.354  -0.486  -0.480  -0.375
206   Q        -0.048   0.188  -0.062   0.080   0.437   0.074  -0.088   0.261  -0.103
207   I        -1.006  -0.957  -0.953  -1.111  -1.044  -1.026  -0.883  -0.814  -0.792
208   K        -1.006  -1.033  -1.002  -0.907  -0.954  -0.921  -0.883  -0.901  -0.849
209   D        -1.006  -0.961  -0.955  -1.021  -0.951  -0.942  -0.883  -0.819  -0.795
210   V         1.081   1.175   1.005   1.030   1.184   0.911   1.104   1.259   0.946
211   I         0.648   0.646   0.715   0.418   0.437   0.543   0.309   0.282   0.384
212   Q        -0.048  -0.075  -0.136   0.212   0.169   0.086  -0.088  -0.125  -0.211
213   I         1.081   1.014   0.966   0.980   0.876   0.778   1.104   0.977   0.874
214   M         2.336   2.409   2.481   2.585   2.712   2.835   2.695   2.814   2.954
215   N        -0.048  -0.193  -0.197  -0.179  -0.433  -0.472  -0.088  -0.291  -0.301
216   D         0.648   0.646   0.715   0.485   0.467   0.568   0.309   0.282   0.384
217   N         2.336   2.409   2.481   2.271   2.395   2.512   2.695   2.814   2.954
218   I         1.081   1.012   0.968   1.012   0.918   0.831   1.104   0.974   0.877
219   D        -0.048  -0.193  -0.197   0.048  -0.181  -0.220  -0.088  -0.291  -0.301
220   K         1.081   1.012   0.968   1.095   1.000   0.946   1.104   0.974   0.877
221   F        -0.048  -0.193  -0.197   0.045  -0.219  -0.267  -0.088  -0.291  -0.301
222   L         2.336   2.409   2.481   2.142   2.242   2.380   2.695   2.814   2.954
223   E        -0.048  -0.074  -0.130   0.009  -0.050  -0.127  -0.088  -0.123  -0.203
224   R         2.336   2.409   2.481   2.527   2.652   2.775   2.695   2.814   2.954
225   Q         0.648   0.646   0.715   0.621   0.595   0.720   0.309   0.282   0.384
226   E         1.081   1.014   0.966   1.172   1.085   1.010   1.104   0.977   0.874
227   R         1.081   1.014   0.966   1.289   1.194   1.105   1.104   0.977   0.874
228   V         0.648   0.782   0.813   0.268   0.518   0.545   0.309   0.548   0.579
229   S         1.081   1.014   0.966   0.969   0.861   0.786   1.104   0.977   0.874
230   L         1.081   1.014   0.966   0.891   0.769   0.698   1.104   0.977   0.874
231   L         2.336   2.409   2.481   2.142   2.242   2.380   2.695   2.814   2.954
232   V         2.336   2.409   2.481   2.271   2.390   2.512   2.695   2.814   2.954
233   D         1.081   1.012   0.968   1.197   1.108   1.015   1.104   0.974   0.877
234   K        -1.006  -1.066  -1.023  -0.963  -1.018  -0.962  -0.883  -0.935  -0.871
235   T         2.336   2.409   2.481   2.421   2.536   2.666   2.695   2.814   2.954
236   S        -0.310  -0.227  -0.253  -0.546  -0.366  -0.430  -0.486  -0.362  -0.387
237   Q        -1.006  -1.030  -0.996  -0.678  -0.729  -0.641  -0.883  -0.898  -0.842
238   L         1.081   1.012   0.968   0.989   0.895   0.853   1.104   0.974   0.877
239   N         1.081   1.012   0.968   1.074   0.987   0.913   1.104   0.974   0.877
240   S        -1.006  -1.066  -1.023  -1.124  -1.214  -1.139  -0.883  -0.935  -0.871
241   S         0.648   0.689   0.730   0.250   0.309   0.357   0.309   0.365   0.415
242   S         1.081   1.012   0.968   1.033   0.932   0.887   1.104   0.974   0.877
243   N        -1.701  -1.660  -1.622  -1.630  -1.586  -1.498  -1.281  -1.222  -1.161
244   K        -1.006  -1.030  -0.996  -1.093  -1.123  -1.079  -0.883  -0.898  -0.842
245   F         2.336   2.409   2.481   2.510   2.636   2.757   2.695   2.814   2.954
246   R        -0.310  -0.212  -0.233  -0.268  -0.113  -0.139  -0.486  -0.360  -0.367
247   R         0.648   0.646   0.715   0.512   0.466   0.572   0.309   0.282   0.384
248   K         0.648   0.646   0.715   0.439   0.447   0.561   0.309   0.282   0.384
249   A         0.648   0.671   0.725   0.469   0.470   0.555   0.309   0.330   0.404
250   V        -1.701  -1.660  -1.622  -1.704  -1.592  -1.574  -1.281  -1.222  -1.161
251   N        -0.310  -0.194  -0.252  -0.447  -0.239  -0.339  -0.486  -0.328  -0.388
252   I        -0.048  -0.011  -0.099  -0.120  -0.044  -0.204  -0.088  -0.038  -0.158
253   K         1.081   1.175   1.005   1.116   1.257   1.035   1.104   1.259   0.946
254   E         0.648   0.782   0.813   0.565   0.821   0.855   0.309   0.548   0.579
255   I        -1.006  -0.915  -0.949  -1.072  -0.934  -0.980  -0.883  -0.767  -0.788
256   M         1.081   1.012   0.968   1.317   1.209   1.118   1.104   0.974   0.877
257   W         2.336   2.409   2.481   2.711   2.839   2.965   2.695   2.814   2.954
258   W         1.081   1.014   0.966   1.526   1.448   1.371   1.104   0.977   0.874
259   Q        -1.701  -1.660  -1.622  -1.438  -1.369  -1.301  -1.281  -1.222  -1.161
260   K        -0.310  -0.212  -0.237  -0.522  -0.386  -0.393  -0.486  -0.360  -0.372
261   V        -0.048  -0.010  -0.105   0.013   0.066  -0.052  -0.088  -0.035  -0.167
262   K         2.336   2.409   2.481   2.271   2.382   2.512   2.695   2.814   2.954
263   N        -0.310  -0.321  -0.245  -0.331  -0.284  -0.173  -0.486  -0.480  -0.375
264   I        -1.006  -1.033  -1.002  -0.880  -0.943  -0.905  -0.883  -0.901  -0.849
265   T        -1.006  -1.066  -1.023  -1.018  -1.144  -1.077  -0.883  -0.935  -0.871
266   L        -0.048  -0.074  -0.130  -0.294  -0.359  -0.451  -0.088  -0.123  -0.203
267   L        -1.006  -0.957  -0.953  -1.156  -1.105  -1.066  -0.883  -0.814  -0.792
268   T        -0.310  -0.330  -0.248  -0.440  -0.441  -0.312  -0.486  -0.495  -0.383
269   F        -1.006  -1.066  -1.023  -0.822  -0.908  -0.860  -0.883  -0.935  -0.871
270   T        -1.006  -0.821  -0.961  -0.811  -0.515  -0.735  -0.883  -0.649  -0.802
271   I         0.648   0.782   0.813   0.275   0.527   0.555   0.309   0.548   0.579
272   I        -0.310  -0.321  -0.245  -0.635  -0.637  -0.511  -0.486  -0.480  -0.375
273   L        -0.048  -0.075  -0.136  -0.102  -0.153  -0.205  -0.088  -0.125  -0.211
274   F        -1.006  -0.915  -0.949  -0.973  -0.876  -0.871  -0.883  -0.767  -0.788
275   V        -0.048  -0.074  -0.130  -0.187  -0.242  -0.354  -0.088  -0.123  -0.203
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   S         1.081   1.175   1.005   0.969   1.107   0.852   1.104   1.259   0.946
282   A        -1.006  -1.066  -1.023  -0.929  -1.051  -0.996  -0.883  -0.935  -0.871
283   A        -1.006  -0.821  -0.961  -0.747  -0.409  -0.682  -0.883  -0.649  -0.802
284   F        -0.310  -0.194  -0.252  -0.408  -0.216  -0.280  -0.486  -0.328  -0.388
285   M        -0.310  -0.227  -0.253  -0.266  -0.120  -0.188  -0.486  -0.362  -0.387
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   F        -0.048  -0.075  -0.136   0.124   0.093  -0.033  -0.088  -0.125  -0.211
289   F        -0.048  -0.074  -0.130   0.031  -0.020  -0.146  -0.088  -0.123  -0.203
290   Y        -0.272  -0.330  -0.285   0.002  -0.080  -0.007  -0.411  -0.487  -0.427
291   L         0.648   0.646   0.715   0.413   0.441   0.569   0.309   0.282   0.384
292   W        -1.006  -1.066  -1.023  -0.658  -0.794  -0.716  -0.883  -0.935  -0.871
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12255
Output conservation file - output/Q12255
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
