1     M         1.821   1.834   1.880   2.162   2.183   2.262   2.000   2.019   2.087
2     S         1.821   1.834   1.880   1.758   1.780   1.855   2.000   2.019   2.087
3     F         1.821   1.834   1.880   2.128   2.152   2.228   2.000   2.019   2.087
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     F         0.367   0.386   0.372   0.674   0.705   0.686   0.159   0.189   0.155
7     D         0.367   0.386   0.372   0.213   0.246   0.197   0.159   0.189   0.155
8     I         0.367   0.386   0.372   0.245   0.275   0.248   0.159   0.189   0.155
9     E         0.367   0.386   0.372   0.127   0.158   0.123   0.159   0.189   0.155
10    A        -0.688  -0.683  -0.641  -0.680  -0.675  -0.603  -0.762  -0.751  -0.686
11    Q         0.367   0.386   0.372   0.199   0.227   0.221   0.159   0.189   0.155
12    S        -0.688  -0.683  -0.641  -0.787  -0.772  -0.710  -0.762  -0.751  -0.686
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    S         0.367   0.386   0.372   0.177   0.209   0.177   0.159   0.189   0.155
16    K         0.367   0.386   0.372   0.195   0.227   0.188   0.159   0.189   0.155
17    G         0.367   0.386   0.372   0.493   0.525   0.490   0.159   0.189   0.155
18    N         1.821   1.834   1.880   1.902   1.924   2.000   2.000   2.019   2.087
19    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    S        -0.688  -0.683  -0.641  -0.626  -0.612  -0.548  -0.762  -0.751  -0.686
27    T        -0.688  -0.683  -0.641  -0.763  -0.761  -0.686  -0.762  -0.751  -0.686
28    N        -0.688  -0.683  -0.641  -0.801  -0.795  -0.724  -0.762  -0.751  -0.686
29    Q         0.367   0.386   0.372   0.018   0.049   0.016   0.159   0.189   0.155
30    K         0.367   0.386   0.370   0.177   0.209   0.173   0.159   0.189   0.151
31    T        -0.688  -0.683  -0.641  -0.740  -0.738  -0.663  -0.762  -0.751  -0.686
32    K         0.367   0.386   0.370   0.311   0.343   0.303   0.159   0.189   0.151
33    E         0.238   0.247   0.291  -0.033  -0.027   0.048  -0.071  -0.057   0.009
34    L        -0.554  -0.524  -0.558  -0.655  -0.616  -0.650  -0.589  -0.547  -0.581
35    S        -1.345  -1.336  -1.301  -1.175  -1.159  -1.101  -1.107  -1.092  -1.033
36    N        -0.554  -0.573  -0.584  -0.380  -0.412  -0.410  -0.589  -0.612  -0.615
37    L        -0.554  -0.588  -0.574  -0.710  -0.766  -0.735  -0.589  -0.631  -0.602
38    I         0.238   0.247   0.291  -0.134  -0.119  -0.046  -0.071  -0.057   0.009
39    E        -0.554  -0.573  -0.584  -0.692  -0.724  -0.739  -0.589  -0.612  -0.615
40    T        -0.554  -0.588  -0.574  -0.523  -0.582  -0.568  -0.589  -0.631  -0.602
41    F        -0.554  -0.565  -0.577  -0.541  -0.558  -0.545  -0.589  -0.602  -0.606
42    A        -0.554  -0.565  -0.577  -0.640  -0.669  -0.668  -0.589  -0.602  -0.606
43    E        -1.345  -1.336  -1.301  -1.523  -1.497  -1.452  -1.107  -1.092  -1.033
44    Q         0.238   0.247   0.291  -0.072  -0.062   0.007  -0.071  -0.057   0.009
45    S        -0.554  -0.565  -0.577  -0.718  -0.751  -0.776  -0.589  -0.602  -0.606
46    R         0.238   0.247   0.292  -0.037  -0.027   0.041  -0.071  -0.056   0.011
47    V         0.537   0.589   0.470   0.414   0.492   0.318   0.447   0.532   0.326
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    L         0.537   0.473   0.431   0.472   0.384   0.336   0.447   0.339   0.258
56    E        -0.554  -0.573  -0.584  -0.666  -0.699  -0.708  -0.589  -0.612  -0.615
57    K        -0.554  -0.573  -0.584  -0.455  -0.480  -0.493  -0.589  -0.612  -0.615
58    E         0.238   0.247   0.292  -0.050  -0.033   0.041  -0.071  -0.056   0.011
59    C        -1.345  -1.336  -1.301  -0.980  -0.980  -0.905  -1.107  -1.092  -1.033
60    T        -1.345  -1.336  -1.301  -1.218  -1.211  -1.145  -1.107  -1.092  -1.033
61    K         0.238   0.247   0.292  -0.090  -0.082  -0.010  -0.071  -0.056   0.011
62    I         0.537   0.552   0.461   0.551   0.576   0.437   0.447   0.471   0.310
63    G         1.821   1.834   1.880   2.040   2.063   2.139   2.000   2.019   2.087
64    S         0.238   0.247   0.291   0.052   0.066   0.135  -0.071  -0.057   0.009
65    K        -0.554  -0.524  -0.558  -0.548  -0.498  -0.558  -0.589  -0.547  -0.581
66    R         0.537   0.576   0.469   0.645   0.711   0.533   0.447   0.511   0.323
67    D         1.821   1.834   1.880   1.887   1.907   1.985   2.000   2.019   2.087
68    S        -1.345  -1.336  -1.301  -1.045  -1.012  -0.970  -1.107  -1.092  -1.033
69    K        -1.345  -1.336  -1.301  -1.315  -1.275  -1.242  -1.107  -1.092  -1.033
70    E        -1.345  -1.336  -1.301  -1.523  -1.514  -1.452  -1.107  -1.092  -1.033
71    L         1.821   1.834   1.880   1.665   1.685   1.761   2.000   2.019   2.087
72    R         1.821   1.834   1.880   1.933   1.957   2.031   2.000   2.019   2.087
73    Y        -1.345  -1.336  -1.301  -0.878  -0.876  -0.802  -1.107  -1.092  -1.033
74    K        -0.554  -0.573  -0.584  -0.528  -0.563  -0.579  -0.589  -0.612  -0.615
75    I        -0.554  -0.588  -0.574  -0.496  -0.541  -0.515  -0.589  -0.631  -0.602
76    E        -1.345  -1.336  -1.301  -1.325  -1.304  -1.252  -1.107  -1.092  -1.033
77    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    E        -0.554  -0.573  -0.584  -0.579  -0.603  -0.607  -0.589  -0.612  -0.615
79    L         0.537   0.576   0.469   0.414   0.473   0.315   0.447   0.511   0.323
80    I         1.821   1.834   1.880   1.807   1.828   1.904   2.000   2.019   2.087
81    P        -0.554  -0.588  -0.574  -0.263  -0.330  -0.308  -0.589  -0.631  -0.602
82    N        -0.554  -0.565  -0.577  -0.666  -0.688  -0.698  -0.589  -0.602  -0.606
83    C        -0.554  -0.516  -0.560  -0.418  -0.367  -0.409  -0.589  -0.536  -0.584
84    T        -0.554  -0.573  -0.584  -0.609  -0.643  -0.688  -0.589  -0.612  -0.615
85    S        -1.345  -1.336  -1.301  -1.436  -1.416  -1.364  -1.107  -1.092  -1.033
86    V        -1.345  -1.336  -1.301  -1.080  -1.046  -1.006  -1.107  -1.092  -1.033
87    R        -1.345  -1.336  -1.301  -1.234  -1.219  -1.161  -1.107  -1.092  -1.033
88    D        -1.345  -1.336  -1.301  -1.364  -1.359  -1.292  -1.107  -1.092  -1.033
89    K        -0.554  -0.588  -0.574  -0.455  -0.502  -0.478  -0.589  -0.631  -0.602
90    I        -0.554  -0.524  -0.558  -0.718  -0.665  -0.739  -0.589  -0.547  -0.581
91    E        -1.345  -1.336  -1.301  -1.364  -1.362  -1.292  -1.107  -1.092  -1.033
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    S        -0.554  -0.565  -0.577  -0.622  -0.655  -0.681  -0.589  -0.602  -0.606
96    N        -0.554  -0.524  -0.558  -0.536  -0.484  -0.547  -0.589  -0.547  -0.581
97    I        -1.345  -1.336  -1.301  -1.256  -1.256  -1.183  -1.107  -1.092  -1.033
98    L         0.238   0.247   0.292  -0.143  -0.125  -0.052  -0.071  -0.056   0.011
99    I        -0.688  -0.683  -0.641  -0.805  -0.788  -0.729  -0.762  -0.751  -0.686
100   H        -0.688  -0.683  -0.641  -0.740  -0.739  -0.663  -0.762  -0.751  -0.686
101   Q        -1.345  -1.336  -1.301  -1.302  -1.284  -1.229  -1.107  -1.092  -1.033
102   N        -0.554  -0.524  -0.558  -0.548  -0.494  -0.561  -0.589  -0.547  -0.581
103   G        -0.554  -0.573  -0.584  -0.387  -0.426  -0.451  -0.589  -0.612  -0.615
104   K         1.821   1.834   1.880   1.864   1.886   1.962   2.000   2.019   2.087
105   L        -0.554  -0.524  -0.558  -0.576  -0.539  -0.562  -0.589  -0.547  -0.581
106   S        -1.345  -1.336  -1.301  -1.141  -1.117  -1.067  -1.107  -1.092  -1.033
107   A        -1.345  -1.336  -1.301  -1.059  -1.036  -0.985  -1.107  -1.092  -1.033
108   D         0.537   0.473   0.431   0.601   0.496   0.424   0.447   0.339   0.258
109   F         0.537   0.473   0.431   0.845   0.744   0.667   0.447   0.339   0.258
110   K         0.238   0.247   0.292  -0.090  -0.079  -0.010  -0.071  -0.056   0.011
111   N        -1.345  -1.336  -1.301  -0.972  -0.951  -0.896  -1.107  -1.092  -1.033
112   L         0.537   0.473   0.431   0.406   0.310   0.245   0.447   0.339   0.258
113   K        -1.345  -1.336  -1.301  -1.405  -1.387  -1.333  -1.107  -1.092  -1.033
114   T        -1.345  -1.336  -1.301  -1.285  -1.272  -1.213  -1.107  -1.092  -1.033
115   K        -1.345  -1.336  -1.301  -1.481  -1.460  -1.409  -1.107  -1.092  -1.033
116   Y        -0.554  -0.588  -0.574  -0.430  -0.512  -0.509  -0.589  -0.631  -0.602
117   Q        -1.345  -1.336  -1.301  -1.439  -1.428  -1.367  -1.107  -1.092  -1.033
118   S        -0.554  -0.588  -0.574  -0.501  -0.544  -0.519  -0.589  -0.631  -0.602
119   L        -0.554  -0.573  -0.584  -0.716  -0.752  -0.755  -0.589  -0.612  -0.615
120   Q        -0.554  -0.499  -0.543  -0.697  -0.600  -0.687  -0.589  -0.514  -0.562
121   Q        -1.345  -1.336  -1.301  -1.325  -1.307  -1.252  -1.107  -1.092  -1.033
122   S        -1.345  -1.336  -1.301  -1.273  -1.257  -1.200  -1.107  -1.092  -1.033
123   Y        -0.554  -0.588  -0.574  -0.245  -0.324  -0.294  -0.589  -0.631  -0.602
124   N        -0.554  -0.516  -0.560  -0.635  -0.578  -0.637  -0.589  -0.536  -0.584
125   Q        -1.345  -1.336  -1.301  -1.378  -1.358  -1.306  -1.107  -1.092  -1.033
126   R         0.537   0.473   0.431   0.666   0.569   0.494   0.447   0.339   0.258
127   K        -1.345  -1.336  -1.301  -1.405  -1.408  -1.333  -1.107  -1.092  -1.033
128   S        -1.345  -1.336  -1.301  -1.187  -1.172  -1.113  -1.107  -1.092  -1.033
129   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   K         0.537   0.589   0.470   0.385   0.467   0.281   0.447   0.532   0.326
134   T        -0.554  -0.565  -0.577  -0.373  -0.378  -0.393  -0.589  -0.602  -0.606
135   P         0.537   0.473   0.431   0.876   0.779   0.699   0.447   0.339   0.258
136   I         0.537   0.552   0.461   0.458   0.482   0.316   0.447   0.471   0.310
137   S        -0.554  -0.499  -0.543  -0.455  -0.368  -0.432  -0.589  -0.514  -0.562
138   P        -1.345  -1.336  -1.301  -1.234  -1.242  -1.161  -1.107  -1.092  -1.033
139   G        -1.345  -1.336  -1.301  -1.225  -1.208  -1.151  -1.107  -1.092  -1.033
140   T        -0.554  -0.573  -0.584  -0.642  -0.688  -0.728  -0.589  -0.612  -0.615
141   S        -0.554  -0.588  -0.574  -0.635  -0.685  -0.672  -0.589  -0.631  -0.602
142   K        -0.554  -0.588  -0.574  -0.551  -0.612  -0.588  -0.589  -0.631  -0.602
143   E        -0.554  -0.524  -0.558  -0.599  -0.557  -0.594  -0.589  -0.547  -0.581
144   R        -1.345  -1.336  -1.301  -1.059  -1.029  -0.985  -1.107  -1.092  -1.033
145   K        -1.345  -1.336  -1.301  -1.279  -1.261  -1.206  -1.107  -1.092  -1.033
146   D        -0.554  -0.565  -0.577  -0.663  -0.695  -0.710  -0.589  -0.602  -0.606
147   I        -1.345  -1.336  -1.301  -1.491  -1.486  -1.420  -1.107  -1.092  -1.033
148   H         0.537   0.552   0.461   0.806   0.833   0.683   0.447   0.471   0.310
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -0.688  -0.680  -0.641  -0.544  -0.507  -0.466  -0.762  -0.748  -0.686
159   -        -0.688  -0.680  -0.641  -0.674  -0.659  -0.596  -0.762  -0.748  -0.686
160   -         0.367   0.346   0.354   0.185   0.141   0.141   0.159   0.120   0.122
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -         0.367   0.346   0.354   0.306   0.273   0.285   0.159   0.120   0.122
165   -        -0.688  -0.680  -0.641  -0.402  -0.389  -0.322  -0.762  -0.748  -0.686
166   P         0.537   0.552   0.461   0.857   0.885   0.728   0.447   0.471   0.310
167   R        -1.345  -1.336  -1.301  -1.351  -1.329  -1.279  -1.107  -1.092  -1.033
168   T        -1.345  -1.336  -1.301  -1.456  -1.437  -1.385  -1.107  -1.092  -1.033
169   E        -0.554  -0.516  -0.560  -0.581  -0.516  -0.601  -0.589  -0.536  -0.584
170   A        -0.554  -0.516  -0.560  -0.548  -0.490  -0.565  -0.589  -0.536  -0.584
171   V         0.238   0.247   0.292   0.078   0.091   0.161  -0.071  -0.056   0.011
172   R        -1.345  -1.336  -1.301  -1.098  -1.063  -1.024  -1.107  -1.092  -1.033
173   Q        -0.554  -0.516  -0.560  -0.661  -0.586  -0.697  -0.589  -0.536  -0.584
174   D        -1.345  -1.336  -1.301  -1.269  -1.271  -1.196  -1.107  -1.092  -1.033
175   P        -0.554  -0.565  -0.577  -0.467  -0.506  -0.501  -0.589  -0.602  -0.606
176   E        -0.554  -0.573  -0.584  -0.551  -0.582  -0.574  -0.589  -0.612  -0.615
177   S         0.537   0.552   0.461   0.532   0.558   0.416   0.447   0.471   0.310
178   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   N        -1.345  -1.336  -1.301  -1.273  -1.256  -1.200  -1.107  -1.092  -1.033
186   E         1.821   1.834   1.880   1.719   1.738   1.815   2.000   2.019   2.087
187   Q        -0.554  -0.499  -0.543  -0.564  -0.463  -0.555  -0.589  -0.514  -0.562
188   S         0.537   0.589   0.470   0.618   0.706   0.502   0.447   0.532   0.326
189   P         1.821   1.834   1.880   2.145   2.171   2.245   2.000   2.019   2.087
190   L         1.821   1.834   1.880   1.665   1.685   1.761   2.000   2.019   2.087
191   L         0.537   0.473   0.431   0.487   0.401   0.357   0.447   0.339   0.258
192   H         0.537   0.576   0.469   0.725   0.794   0.592   0.447   0.511   0.323
193   N        -0.554  -0.516  -0.560  -0.571  -0.509  -0.577  -0.589  -0.536  -0.584
194   E        -0.688  -0.678  -0.641  -0.844  -0.821  -0.768  -0.762  -0.746  -0.686
195   G        -0.688  -0.678  -0.641  -0.514  -0.493  -0.435  -0.762  -0.746  -0.686
196   Q         0.367   0.336   0.347   0.120   0.074   0.088   0.159   0.103   0.111
197   H        -0.688  -0.678  -0.641  -0.894  -0.896  -0.818  -0.762  -0.746  -0.686
198   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   Q         1.821   1.834   1.880   1.645   1.671   1.741   2.000   2.019   2.087
201   L        -0.688  -0.678  -0.641  -0.894  -0.878  -0.818  -0.762  -0.746  -0.686
202   Q        -0.688  -0.678  -0.641  -0.682  -0.648  -0.604  -0.762  -0.746  -0.686
203   E        -0.688  -0.678  -0.641  -0.659  -0.626  -0.581  -0.762  -0.746  -0.686
204   E        -0.688  -0.678  -0.641  -0.950  -0.921  -0.874  -0.762  -0.746  -0.686
205   Q         1.821   1.834   1.880   1.645   1.671   1.741   2.000   2.019   2.087
206   E        -0.554  -0.524  -0.558  -0.637  -0.595  -0.637  -0.589  -0.547  -0.581
207   Q         0.537   0.473   0.431   0.481   0.400   0.349   0.447   0.339   0.258
208   Q        -0.554  -0.588  -0.574  -0.617  -0.671  -0.628  -0.589  -0.631  -0.602
209   Q         0.537   0.552   0.461   0.336   0.361   0.202   0.447   0.471   0.310
210   Q        -0.554  -0.573  -0.584  -0.780  -0.807  -0.830  -0.589  -0.612  -0.615
211   G        -0.554  -0.573  -0.584  -0.359  -0.409  -0.417  -0.589  -0.612  -0.615
212   L         0.537   0.473   0.431   0.365   0.261   0.188   0.447   0.339   0.258
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   S        -0.554  -0.565  -0.577  -0.548  -0.568  -0.595  -0.589  -0.602  -0.606
215   Q        -0.554  -0.588  -0.574  -0.780  -0.843  -0.814  -0.589  -0.631  -0.602
216   E        -0.554  -0.565  -0.577  -0.564  -0.580  -0.613  -0.589  -0.602  -0.606
217   E         1.821   1.834   1.880   1.719   1.738   1.815   2.000   2.019   2.087
218   L         1.821   1.834   1.880   1.665   1.685   1.761   2.000   2.019   2.087
219   D         0.537   0.473   0.431   0.538   0.424   0.335   0.447   0.339   0.258
220   F         0.537   0.473   0.431   0.925   0.836   0.778   0.447   0.339   0.258
221   Q         0.537   0.589   0.470   0.725   0.816   0.595   0.447   0.532   0.326
222   T         0.537   0.473   0.431   0.577   0.467   0.373   0.447   0.339   0.258
223   I         0.537   0.473   0.431   0.622   0.535   0.486   0.447   0.339   0.258
224   I        -0.554  -0.588  -0.574  -0.648  -0.717  -0.689  -0.589  -0.631  -0.602
225   H        -0.554  -0.565  -0.577  -0.596  -0.613  -0.608  -0.589  -0.602  -0.606
226   Q        -0.554  -0.499  -0.543  -0.666  -0.580  -0.646  -0.589  -0.514  -0.562
227   E         0.537   0.552   0.461   0.445   0.465   0.327   0.447   0.471   0.310
228   R         1.821   1.834   1.880   1.933   1.957   2.031   2.000   2.019   2.087
229   S         0.537   0.473   0.431   0.519   0.420   0.348   0.447   0.339   0.258
230   Q         0.537   0.552   0.461   0.408   0.434   0.296   0.447   0.471   0.310
231   Q        -0.554  -0.573  -0.584  -0.702  -0.731  -0.740  -0.589  -0.612  -0.615
232   I         1.821   1.834   1.880   1.807   1.828   1.904   2.000   2.019   2.087
233   G        -0.554  -0.565  -0.577  -0.521  -0.544  -0.546  -0.589  -0.602  -0.606
234   R        -0.554  -0.573  -0.584  -0.574  -0.619  -0.647  -0.589  -0.612  -0.615
235   I         1.821   1.834   1.880   1.807   1.828   1.904   2.000   2.019   2.087
236   H         0.537   0.473   0.431   0.793   0.691   0.612   0.447   0.339   0.258
237   T        -0.554  -0.565  -0.577  -0.645  -0.676  -0.689  -0.589  -0.602  -0.606
238   A        -0.554  -0.588  -0.574  -0.375  -0.426  -0.413  -0.589  -0.631  -0.602
239   V         0.537   0.473   0.431   0.644   0.541   0.456   0.447   0.339   0.258
240   Q         0.537   0.473   0.431   0.318   0.209   0.121   0.447   0.339   0.258
241   E         1.821   1.834   1.880   1.719   1.738   1.815   2.000   2.019   2.087
242   V         0.537   0.473   0.431   0.644   0.541   0.456   0.447   0.339   0.258
243   N         1.821   1.834   1.880   1.887   1.910   1.985   2.000   2.019   2.087
244   A         0.537   0.473   0.431   0.700   0.594   0.509   0.447   0.339   0.258
245   I         1.821   1.834   1.880   1.807   1.828   1.904   2.000   2.019   2.087
246   F         1.821   1.834   1.880   2.118   2.141   2.217   2.000   2.019   2.087
247   H         0.537   0.589   0.470   0.649   0.726   0.560   0.447   0.532   0.326
248   Q         0.537   0.473   0.431   0.393   0.295   0.226   0.447   0.339   0.258
249   L         1.821   1.834   1.880   1.665   1.685   1.761   2.000   2.019   2.087
250   G         1.821   1.834   1.880   2.040   2.063   2.139   2.000   2.019   2.087
251   S        -0.554  -0.588  -0.574  -0.645  -0.710  -0.684  -0.589  -0.631  -0.602
252   L         1.821   1.834   1.880   1.665   1.685   1.761   2.000   2.019   2.087
253   V         1.821   1.834   1.880   1.950   1.975   2.048   2.000   2.019   2.087
254   K        -1.345  -1.336  -1.301  -1.354  -1.331  -1.282  -1.107  -1.092  -1.033
255   E         0.537   0.473   0.431   0.371   0.259   0.173   0.447   0.339   0.258
256   Q         1.821   1.834   1.880   1.665   1.688   1.761   2.000   2.019   2.087
257   G         1.821   1.834   1.880   2.040   2.063   2.139   2.000   2.019   2.087
258   E         0.537   0.552   0.461   0.458   0.481   0.344   0.447   0.471   0.310
259   Q         1.821   1.834   1.880   1.665   1.688   1.761   2.000   2.019   2.087
260   V         0.537   0.473   0.431   0.599   0.489   0.394   0.447   0.339   0.258
261   T         0.537   0.589   0.470   0.622   0.701   0.519   0.447   0.532   0.326
262   T         1.821   1.834   1.880   1.927   1.953   2.026   2.000   2.019   2.087
263   I         0.238   0.250   0.292   0.078   0.105   0.172  -0.071  -0.052   0.012
264   D        -0.554  -0.573  -0.584  -0.514  -0.563  -0.567  -0.589  -0.612  -0.615
265   E         0.537   0.473   0.431   0.445   0.343   0.276   0.447   0.339   0.258
266   N         1.821   1.834   1.880   1.887   1.910   1.985   2.000   2.019   2.087
267   I         0.537   0.576   0.469   0.551   0.613   0.449   0.447   0.511   0.323
268   S        -1.345  -1.336  -1.301  -1.325  -1.323  -1.252  -1.107  -1.092  -1.033
269   H        -1.345  -1.336  -1.301  -1.172  -1.181  -1.098  -1.107  -1.092  -1.033
270   L         0.537   0.552   0.461   0.472   0.493   0.379   0.447   0.471   0.310
271   H        -0.554  -0.516  -0.560  -0.504  -0.451  -0.502  -0.589  -0.536  -0.584
272   D        -0.554  -0.565  -0.577  -0.442  -0.455  -0.473  -0.589  -0.602  -0.606
273   N         1.821   1.834   1.880   1.887   1.910   1.985   2.000   2.019   2.087
274   M        -0.554  -0.573  -0.584  -0.347  -0.381  -0.429  -0.589  -0.612  -0.615
275   Q         0.537   0.552   0.461   0.458   0.483   0.362   0.447   0.471   0.310
276   N        -1.345  -1.336  -1.301  -1.354  -1.353  -1.282  -1.107  -1.092  -1.033
277   A         1.821   1.834   1.880   2.012   2.035   2.111   2.000   2.019   2.087
278   N         0.537   0.473   0.431   0.555   0.445   0.358   0.447   0.339   0.258
279   K        -0.554  -0.588  -0.574  -0.581  -0.636  -0.623  -0.589  -0.631  -0.602
280   Q         0.238   0.247   0.292  -0.201  -0.185  -0.114  -0.071  -0.056   0.011
281   L         1.821   1.834   1.880   1.665   1.685   1.761   2.000   2.019   2.087
282   T        -1.345  -1.336  -1.301  -0.972  -0.945  -0.896  -1.107  -1.092  -1.033
283   R         0.238   0.247   0.292   0.107   0.122   0.193  -0.071  -0.056   0.011
284   A         1.821   1.834   1.880   2.012   2.035   2.111   2.000   2.019   2.087
285   D        -0.554  -0.573  -0.584  -0.426  -0.449  -0.463  -0.589  -0.612  -0.615
286   Q         0.537   0.589   0.470   0.371   0.456   0.247   0.447   0.532   0.326
287   H         0.238   0.247   0.292   0.443   0.463   0.536  -0.071  -0.056   0.011
288   Q         1.821   1.834   1.880   1.665   1.688   1.761   2.000   2.019   2.087
289   R         0.537   0.473   0.431   0.645   0.544   0.466   0.447   0.339   0.258
290   D        -0.554  -0.516  -0.560  -0.624  -0.561  -0.646  -0.589  -0.536  -0.584
291   R         0.238   0.247   0.292   0.107   0.122   0.193  -0.071  -0.056   0.011
292   N         0.537   0.473   0.431   0.579   0.474   0.392   0.447   0.339   0.258
293   K         0.238   0.247   0.291   0.107   0.121   0.192  -0.071  -0.057   0.009
294   C         0.537   0.473   0.431   1.032   0.946   0.889   0.447   0.339   0.258
295   G         0.537   0.473   0.431   0.727   0.621   0.535   0.447   0.339   0.258
296   K        -1.345  -1.336  -1.301  -1.172  -1.133  -1.098  -1.107  -1.092  -1.033
297   V        -0.554  -0.516  -0.560  -0.430  -0.374  -0.422  -0.589  -0.536  -0.584
298   T         0.238   0.247   0.292  -0.042  -0.033   0.037  -0.071  -0.056   0.011
299   L         1.821   1.834   1.880   1.665   1.685   1.761   2.000   2.019   2.087
300   I        -0.554  -0.573  -0.584  -0.450  -0.467  -0.475  -0.589  -0.612  -0.615
301   I         0.238   0.247   0.292   0.124   0.146   0.218  -0.071  -0.056   0.011
302   I         0.537   0.473   0.431   0.458   0.346   0.257   0.447   0.339   0.258
303   I        -0.554  -0.573  -0.584  -0.409  -0.420  -0.427  -0.589  -0.612  -0.615
304   V         0.537   0.473   0.431   0.644   0.541   0.456   0.447   0.339   0.258
305   V        -0.554  -0.573  -0.584  -0.390  -0.407  -0.435  -0.589  -0.612  -0.615
306   C        -0.554  -0.499  -0.543  -0.300  -0.217  -0.273  -0.589  -0.514  -0.562
307   M        -0.554  -0.516  -0.560  -0.612  -0.566  -0.604  -0.589  -0.536  -0.584
308   V         0.238   0.247   0.291   0.078   0.097   0.167  -0.071  -0.057   0.009
309   V        -0.554  -0.499  -0.543  -0.533  -0.447  -0.511  -0.589  -0.514  -0.562
310   L         0.537   0.473   0.431   0.414   0.318   0.256   0.447   0.339   0.258
311   L        -0.554  -0.524  -0.558  -0.668  -0.625  -0.664  -0.589  -0.547  -0.581
312   A         1.821   1.834   1.880   2.012   2.035   2.111   2.000   2.019   2.087
313   V         0.367   0.386   0.372   0.379   0.413   0.372   0.159   0.189   0.155
314   L         0.537   0.552   0.461   0.361   0.383   0.235   0.447   0.471   0.310
315   S         1.821   1.834   1.880   1.795   1.817   1.892   2.000   2.019   2.087
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12241
Output conservation file - output/Q12241
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
