1     M         1.259   1.264   1.280   1.456   1.464   1.485   1.315   1.320   1.338
2     F        -0.405  -0.400  -0.368  -0.298  -0.290  -0.237  -0.592  -0.583  -0.529
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     R         1.259   1.264   1.280   1.330   1.338   1.362   1.315   1.320   1.338
5     V        -0.405  -0.400  -0.368  -0.512  -0.504  -0.447  -0.592  -0.583  -0.529
6     K        -0.405  -0.400  -0.368  -0.601  -0.594  -0.535  -0.592  -0.583  -0.529
7     I        -0.405  -0.400  -0.368  -0.498  -0.490  -0.433  -0.592  -0.583  -0.529
8     I        -0.405  -0.400  -0.368  -0.447  -0.439  -0.383  -0.592  -0.583  -0.529
9     S         1.259   1.264   1.280   1.117   1.125   1.152   1.315   1.320   1.338
10    Q        -0.405  -0.400  -0.368  -0.479  -0.472  -0.415  -0.592  -0.583  -0.529
11    K        -0.405  -0.400  -0.368  -0.465  -0.458  -0.401  -0.592  -0.583  -0.529
12    R         1.259   1.264   1.280   1.330   1.338   1.362   1.315   1.320   1.338
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    T        -0.405  -0.400  -0.368  -0.479  -0.472  -0.415  -0.592  -0.583  -0.529
22    K        -0.405  -0.400  -0.368  -0.456  -0.448  -0.392  -0.592  -0.583  -0.529
23    S         1.259   1.264   1.280   1.117   1.125   1.152   1.315   1.320   1.338
24    V        -0.405  -0.400  -0.368  -0.512  -0.504  -0.447  -0.592  -0.583  -0.529
25    Q        -0.405  -0.400  -0.368  -0.324  -0.317  -0.263  -0.592  -0.583  -0.529
26    M        -0.405  -0.400  -0.368  -0.320  -0.313  -0.259  -0.592  -0.583  -0.529
27    L        -0.269  -0.316  -0.329  -0.241  -0.339  -0.398  -0.380  -0.451  -0.468
28    E        -1.378  -1.367  -1.331  -1.236  -1.229  -1.159  -1.228  -1.210  -1.151
29    N        -1.378  -1.367  -1.331  -1.250  -1.236  -1.172  -1.228  -1.210  -1.151
30    D        -1.378  -1.367  -1.331  -1.365  -1.349  -1.285  -1.228  -1.210  -1.151
31    Q        -0.269  -0.316  -0.329  -0.188  -0.257  -0.280  -0.380  -0.451  -0.468
32    L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
33    D        -0.269  -0.243  -0.307  -0.241  -0.207  -0.307  -0.380  -0.339  -0.435
34    I         1.259   1.264   1.280   1.248   1.263   1.280   1.315   1.320   1.338
35    L        -0.269  -0.243  -0.307  -0.516  -0.489  -0.551  -0.380  -0.339  -0.435
36    G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
37    Q         1.259   1.264   1.280   1.400   1.418   1.430   1.315   1.320   1.338
38    Q        -0.269  -0.243  -0.307  -0.143  -0.091  -0.212  -0.380  -0.339  -0.435
39    P        -0.269  -0.224  -0.303  -0.312  -0.229  -0.387  -0.380  -0.311  -0.428
40    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    Y        -0.269  -0.316  -0.329  -0.461  -0.533  -0.508  -0.380  -0.451  -0.468
43    K        -1.378  -1.367  -1.331  -1.229  -1.213  -1.151  -1.228  -1.210  -1.151
44    L        -0.269  -0.316  -0.329  -0.450  -0.550  -0.590  -0.380  -0.451  -0.468
45    Y        -0.269  -0.224  -0.303  -0.021   0.053  -0.085  -0.380  -0.311  -0.428
46    T         1.259   1.264   1.280   1.168   1.175   1.202   1.315   1.320   1.338
47    Q         1.259   1.264   1.280   1.400   1.418   1.430   1.315   1.320   1.338
48    I         1.259   1.264   1.280   1.248   1.263   1.280   1.315   1.320   1.338
49    C         1.259   1.264   1.280   1.548   1.554   1.576   1.315   1.320   1.338
50    S        -1.378  -1.367  -1.331  -1.575  -1.561  -1.492  -1.228  -1.210  -1.151
51    I        -0.269  -0.316  -0.329  -0.042  -0.130  -0.172  -0.380  -0.451  -0.468
52    Y         1.259   1.264   1.280   1.502   1.507   1.530   1.315   1.320   1.338
53    R        -0.269  -0.316  -0.329  -0.415  -0.467  -0.496  -0.380  -0.451  -0.468
54    V        -0.269  -0.316  -0.329  -0.086  -0.157  -0.202  -0.380  -0.451  -0.468
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    P        -0.405  -0.400  -0.368  -0.437  -0.438  -0.374  -0.592  -0.583  -0.529
57    D         1.259   1.264   1.280   1.305   1.307   1.336   1.315   1.320   1.338
58    P        -1.378  -1.367  -1.331  -1.236  -1.225  -1.159  -1.228  -1.210  -1.151
59    S        -1.378  -1.367  -1.331  -1.398  -1.395  -1.318  -1.228  -1.210  -1.151
60    A        -1.378  -1.367  -1.331  -1.379  -1.341  -1.299  -1.228  -1.210  -1.151
61    H        -1.378  -1.367  -1.331  -1.098  -1.058  -1.023  -1.228  -1.210  -1.151
62    D        -0.269  -0.243  -0.307  -0.332  -0.286  -0.414  -0.380  -0.339  -0.435
63    H        -0.269  -0.316  -0.329  -0.127  -0.198  -0.200  -0.380  -0.451  -0.468
64    I         1.259   1.264   1.280   1.248   1.263   1.280   1.315   1.320   1.338
65    V        -0.269  -0.224  -0.303  -0.388  -0.309  -0.473  -0.380  -0.311  -0.428
66    N        -1.378  -1.367  -1.331  -1.098  -1.087  -1.023  -1.228  -1.210  -1.151
67    T        -0.269  -0.243  -0.307  -0.392  -0.346  -0.453  -0.380  -0.339  -0.435
68    L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
69    T        -1.378  -1.367  -1.331  -1.295  -1.274  -1.216  -1.228  -1.210  -1.151
70    R        -1.378  -1.367  -1.331  -1.373  -1.331  -1.293  -1.228  -1.210  -1.151
71    G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
72    L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
73    E        -0.269  -0.243  -0.307  -0.239  -0.203  -0.303  -0.380  -0.339  -0.435
74    T        -0.269  -0.316  -0.329  -0.277  -0.351  -0.398  -0.380  -0.451  -0.468
75    L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
76    A        -0.269  -0.316  -0.329  -0.353  -0.431  -0.440  -0.380  -0.451  -0.468
77    K        -0.269  -0.316  -0.329  -0.227  -0.309  -0.325  -0.380  -0.451  -0.468
78    N        -1.378  -1.367  -1.331  -1.354  -1.328  -1.275  -1.228  -1.210  -1.151
79    F         1.259   1.264   1.280   1.391   1.409   1.421   1.315   1.320   1.338
80    Q        -0.269  -0.316  -0.329  -0.176  -0.247  -0.269  -0.380  -0.451  -0.468
81    W         1.259   1.264   1.280   1.574   1.579   1.600   1.315   1.320   1.338
82    L        -1.378  -1.367  -1.331  -1.531  -1.542  -1.448  -1.228  -1.210  -1.151
83    A         1.259   1.264   1.280   1.331   1.330   1.362   1.315   1.320   1.338
84    G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
85    N        -0.269  -0.316  -0.329  -0.123  -0.193  -0.226  -0.380  -0.451  -0.468
86    V         1.259   1.264   1.280   1.313   1.320   1.345   1.315   1.320   1.338
87    V         1.259   1.264   1.280   1.313   1.320   1.345   1.315   1.320   1.338
88    N        -0.269  -0.243  -0.307  -0.168  -0.119  -0.235  -0.380  -0.339  -0.435
89    E        -0.269  -0.243  -0.307  -0.243  -0.209  -0.308  -0.380  -0.339  -0.435
90    G        -0.405  -0.400  -0.368  -0.433  -0.419  -0.370  -0.592  -0.583  -0.529
91    A        -0.405  -0.400  -0.368  -0.410  -0.400  -0.347  -0.592  -0.583  -0.529
92    D        -0.405  -0.400  -0.368  -0.470  -0.471  -0.407  -0.592  -0.583  -0.529
93    E        -0.405  -0.400  -0.368  -0.327  -0.316  -0.266  -0.592  -0.583  -0.529
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    G        -0.269  -0.316  -0.329  -0.227  -0.315  -0.327  -0.380  -0.451  -0.468
96    N        -1.378  -1.367  -1.331  -1.314  -1.295  -1.235  -1.228  -1.210  -1.151
97    T        -0.269  -0.243  -0.307  -0.461  -0.410  -0.535  -0.380  -0.339  -0.435
98    G        -0.269  -0.224  -0.303  -0.104  -0.049  -0.145  -0.380  -0.311  -0.428
99    T        -1.378  -1.367  -1.331  -1.584  -1.577  -1.500  -1.228  -1.210  -1.151
100   Y        -0.269  -0.316  -0.329  -0.071  -0.134  -0.158  -0.380  -0.451  -0.468
101   R        -0.269  -0.316  -0.329  -0.196  -0.264  -0.298  -0.380  -0.451  -0.468
102   I         1.259   1.264   1.280   1.248   1.263   1.280   1.315   1.320   1.338
103   V        -1.378  -1.367  -1.331  -1.343  -1.322  -1.264  -1.228  -1.210  -1.151
104   P        -0.269  -0.316  -0.329  -0.355  -0.430  -0.443  -0.380  -0.451  -0.468
105   S        -0.269  -0.316  -0.329  -0.660  -0.750  -0.758  -0.380  -0.451  -0.468
106   D        -1.378  -1.367  -1.331  -1.273  -1.269  -1.195  -1.228  -1.210  -1.151
107   K        -0.269  -0.224  -0.303  -0.196  -0.114  -0.254  -0.380  -0.311  -0.428
108   I        -0.269  -0.243  -0.307  -0.355  -0.303  -0.428  -0.380  -0.339  -0.435
109   P         1.259   1.264   1.280   1.326   1.332   1.358   1.315   1.320   1.338
110   -         1.259   1.264   1.280   1.329   1.348   1.361   1.315   1.320   1.338
111   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
112   I        -0.269  -0.243  -0.307  -0.287  -0.239  -0.348  -0.380  -0.339  -0.435
113   V         1.259   1.264   1.280   1.313   1.320   1.345   1.315   1.320   1.338
114   Q        -0.269  -0.316  -0.329  -0.164  -0.231  -0.259  -0.380  -0.451  -0.468
115   D         1.259   1.264   1.280   1.305   1.307   1.336   1.315   1.320   1.338
116   L        -0.269  -0.316  -0.329  -0.388  -0.497  -0.533  -0.380  -0.451  -0.468
117   R        -1.378  -1.367  -1.331  -1.482  -1.432  -1.401  -1.228  -1.210  -1.151
118   E        -0.269  -0.316  -0.329  -0.241  -0.329  -0.344  -0.380  -0.451  -0.468
119   D        -1.378  -1.367  -1.331  -1.311  -1.292  -1.232  -1.228  -1.210  -1.151
120   L        -0.405  -0.400  -0.368  -0.693  -0.698  -0.625  -0.592  -0.583  -0.529
121   S        -0.269  -0.243  -0.307  -0.415  -0.367  -0.464  -0.380  -0.339  -0.435
122   A        -1.378  -1.367  -1.331  -1.520  -1.500  -1.437  -1.228  -1.210  -1.151
123   P         1.259   1.264   1.280   1.326   1.332   1.358   1.315   1.320   1.338
124   T        -0.405  -0.400  -0.368  -0.758  -0.750  -0.689  -0.592  -0.583  -0.529
125   M         1.259   1.264   1.280   1.468   1.491   1.497   1.315   1.320   1.338
126   D        -0.269  -0.316  -0.329  -0.243  -0.331  -0.345  -0.380  -0.451  -0.468
127   S        -1.378  -1.367  -1.331  -1.354  -1.342  -1.275  -1.228  -1.210  -1.151
128   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
129   E        -1.378  -1.367  -1.331  -1.252  -1.231  -1.174  -1.228  -1.210  -1.151
130   K        -1.378  -1.367  -1.331  -1.210  -1.183  -1.133  -1.228  -1.210  -1.151
131   A        -0.269  -0.243  -0.307  -0.211  -0.177  -0.278  -0.380  -0.339  -0.435
132   D        -1.378  -1.367  -1.331  -1.351  -1.319  -1.272  -1.228  -1.210  -1.151
133   F         1.259   1.264   1.280   1.391   1.409   1.421   1.315   1.320   1.338
134   P         1.259   1.264   1.280   1.326   1.332   1.358   1.315   1.320   1.338
135   I        -1.378  -1.367  -1.331  -1.169  -1.145  -1.092  -1.228  -1.210  -1.151
136   Y        -0.269  -0.316  -0.329  -0.125  -0.182  -0.207  -0.380  -0.451  -0.468
137   M         1.259   1.264   1.280   1.468   1.491   1.497   1.315   1.320   1.338
138   L        -0.269  -0.243  -0.307  -0.478  -0.449  -0.506  -0.380  -0.339  -0.435
139   D        -0.269  -0.243  -0.307  -0.123  -0.092  -0.168  -0.380  -0.339  -0.435
140   E         1.259   1.264   1.280   1.300   1.301   1.332   1.315   1.320   1.338
141   K        -1.378  -1.367  -1.331  -1.477  -1.435  -1.395  -1.228  -1.210  -1.151
142   T        -1.378  -1.367  -1.331  -1.316  -1.309  -1.237  -1.228  -1.210  -1.151
143   F        -1.378  -1.367  -1.331  -1.437  -1.408  -1.356  -1.228  -1.210  -1.151
144   A         1.259   1.264   1.280   1.331   1.330   1.362   1.315   1.320   1.338
145   P         1.259   1.264   1.280   1.326   1.332   1.358   1.315   1.320   1.338
146   C        -0.269  -0.316  -0.329  -0.104  -0.157  -0.180  -0.380  -0.451  -0.468
147   M        -0.269  -0.316  -0.329  -0.349  -0.394  -0.413  -0.380  -0.451  -0.468
148   T         1.259   1.264   1.280   1.168   1.175   1.202   1.315   1.320   1.338
149   I        -0.269  -0.224  -0.303  -0.287  -0.210  -0.342  -0.380  -0.311  -0.428
150   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   P         1.259   1.264   1.280   1.326   1.332   1.358   1.315   1.320   1.338
153   G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
154   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   I        -0.269  -0.243  -0.307  -0.450  -0.400  -0.541  -0.380  -0.339  -0.435
157   G        -0.269  -0.316  -0.329  -0.148  -0.225  -0.255  -0.380  -0.451  -0.468
158   M        -0.269  -0.316  -0.329  -0.349  -0.394  -0.413  -0.380  -0.451  -0.468
159   A        -0.269  -0.316  -0.329  -0.231  -0.319  -0.330  -0.380  -0.451  -0.468
160   A        -0.269  -0.316  -0.329  -0.415  -0.480  -0.496  -0.380  -0.451  -0.468
161   K        -1.378  -1.367  -1.331  -1.393  -1.359  -1.312  -1.228  -1.210  -1.151
162   S        -1.378  -1.367  -1.331  -1.252  -1.250  -1.174  -1.228  -1.210  -1.151
163   G        -1.378  -1.367  -1.331  -1.226  -1.216  -1.149  -1.228  -1.210  -1.151
164   P         1.259   1.264   1.280   1.326   1.332   1.358   1.315   1.320   1.338
165   V         1.259   1.264   1.280   1.313   1.320   1.345   1.315   1.320   1.338
166   F         1.259   1.264   1.280   1.391   1.409   1.421   1.315   1.320   1.338
167   A        -1.378  -1.367  -1.331  -1.520  -1.500  -1.437  -1.228  -1.210  -1.151
168   V        -0.269  -0.316  -0.329  -0.555  -0.638  -0.626  -0.380  -0.451  -0.468
169   Q         1.259   1.264   1.280   1.400   1.418   1.430   1.315   1.320   1.338
170   A         1.259   1.264   1.280   1.331   1.330   1.362   1.315   1.320   1.338
171   N        -0.269  -0.316  -0.329  -0.334  -0.406  -0.417  -0.380  -0.451  -0.468
172   F        -0.269  -0.243  -0.307  -0.071  -0.024  -0.126  -0.380  -0.339  -0.435
173   I         1.259   1.264   1.280   1.248   1.263   1.280   1.315   1.320   1.338
174   S        -1.378  -1.367  -1.331  -1.390  -1.381  -1.310  -1.228  -1.210  -1.151
175   G        -0.269  -0.224  -0.303  -0.186  -0.124  -0.241  -0.380  -0.311  -0.428
176   G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
177   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
178   V        -0.269  -0.316  -0.329  -0.555  -0.638  -0.626  -0.380  -0.451  -0.468
179   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
180   T         1.259   1.264   1.280   1.168   1.175   1.202   1.315   1.320   1.338
181   I        -0.269  -0.316  -0.329  -0.186  -0.258  -0.302  -0.380  -0.451  -0.468
182   V        -0.269  -0.316  -0.329  -0.555  -0.638  -0.626  -0.380  -0.451  -0.468
183   G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
184   Q        -0.269  -0.243  -0.307  -0.038   0.008  -0.090  -0.380  -0.339  -0.435
185   H         1.259   1.264   1.280   1.557   1.563   1.584   1.315   1.320   1.338
186   N        -0.269  -0.316  -0.329  -0.123  -0.193  -0.226  -0.380  -0.451  -0.468
187   I        -1.378  -1.367  -1.331  -1.300  -1.288  -1.221  -1.228  -1.210  -1.151
188   M        -0.269  -0.243  -0.307  -0.115  -0.053  -0.195  -0.380  -0.339  -0.435
189   D         1.259   1.264   1.280   1.305   1.307   1.336   1.315   1.320   1.338
190   I        -0.269  -0.316  -0.329  -0.241  -0.329  -0.353  -0.380  -0.451  -0.468
191   T         1.259   1.264   1.280   1.168   1.175   1.202   1.315   1.320   1.338
192   G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
193   Q        -0.269  -0.243  -0.307  -0.306  -0.252  -0.405  -0.380  -0.339  -0.435
194   E        -0.269  -0.316  -0.329  -0.217  -0.308  -0.323  -0.380  -0.451  -0.468
195   S        -1.378  -1.367  -1.331  -1.195  -1.190  -1.118  -1.228  -1.210  -1.151
196   I        -0.269  -0.224  -0.303  -0.287  -0.210  -0.342  -0.380  -0.311  -0.428
197   I        -0.269  -0.243  -0.307  -0.287  -0.239  -0.348  -0.380  -0.339  -0.435
198   N        -0.269  -0.316  -0.329  -0.396  -0.455  -0.473  -0.380  -0.451  -0.468
199   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
200   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
201   N        -0.269  -0.316  -0.329  -0.396  -0.455  -0.473  -0.380  -0.451  -0.468
202   K         1.259   1.264   1.280   1.339   1.350   1.370   1.315   1.320   1.338
203   S        -0.269  -0.316  -0.329  -0.308  -0.401  -0.437  -0.380  -0.451  -0.468
204   C         1.259   1.264   1.280   1.548   1.554   1.576   1.315   1.320   1.338
205   H        -1.378  -1.367  -1.331  -1.080  -1.043  -1.005  -1.228  -1.210  -1.151
206   Q        -0.269  -0.316  -0.329  -0.172  -0.249  -0.266  -0.380  -0.451  -0.468
207   K        -0.269  -0.316  -0.329  -0.227  -0.309  -0.325  -0.380  -0.451  -0.468
208   P        -0.269  -0.224  -0.303  -0.176  -0.105  -0.228  -0.380  -0.311  -0.428
209   F         1.259   1.264   1.280   1.391   1.409   1.421   1.315   1.320   1.338
210   S        -0.269  -0.316  -0.329  -0.461  -0.542  -0.576  -0.380  -0.451  -0.468
211   D        -1.378  -1.367  -1.331  -1.273  -1.256  -1.195  -1.228  -1.210  -1.151
212   E         1.259   1.264   1.280   1.300   1.301   1.332   1.315   1.320   1.338
213   E         1.259   1.264   1.280   1.300   1.301   1.332   1.315   1.320   1.338
214   L        -0.269  -0.243  -0.307  -0.542  -0.517  -0.581  -0.380  -0.339  -0.435
215   L        -1.378  -1.367  -1.331  -1.540  -1.554  -1.457  -1.228  -1.210  -1.151
216   I        -1.378  -1.367  -1.331  -1.303  -1.273  -1.224  -1.228  -1.210  -1.151
217   G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
218   N         1.259   1.264   1.280   1.370   1.376   1.400   1.315   1.320   1.338
219   I        -0.269  -0.243  -0.307  -0.215  -0.163  -0.264  -0.380  -0.339  -0.435
220   D        -0.269  -0.243  -0.307  -0.241  -0.207  -0.307  -0.380  -0.339  -0.435
221   K        -0.269  -0.316  -0.329  -0.200  -0.262  -0.300  -0.380  -0.451  -0.468
222   S        -1.378  -1.367  -1.331  -1.415  -1.410  -1.334  -1.228  -1.210  -1.151
223   K        -1.378  -1.367  -1.331  -1.210  -1.197  -1.133  -1.228  -1.210  -1.151
224   S        -0.269  -0.316  -0.329  -0.386  -0.463  -0.508  -0.380  -0.451  -0.468
225   I        -0.269  -0.243  -0.307  -0.287  -0.239  -0.348  -0.380  -0.339  -0.435
226   P         1.259   1.264   1.280   1.326   1.332   1.358   1.315   1.320   1.338
227   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
228   F        -0.269  -0.224  -0.303  -0.314  -0.224  -0.403  -0.380  -0.311  -0.428
229   D        -1.378  -1.367  -1.331  -1.500  -1.468  -1.417  -1.228  -1.210  -1.151
230   E         1.259   1.264   1.280   1.300   1.301   1.332   1.315   1.320   1.338
231   T        -1.378  -1.367  -1.331  -1.409  -1.398  -1.329  -1.228  -1.210  -1.151
232   W        -0.269  -0.316  -0.329  -0.119  -0.190  -0.190  -0.380  -0.451  -0.468
233   E        -1.378  -1.367  -1.331  -1.234  -1.216  -1.156  -1.228  -1.210  -1.151
234   P        -1.378  -1.367  -1.331  -1.575  -1.552  -1.492  -1.228  -1.210  -1.151
235   D        -1.378  -1.367  -1.331  -1.231  -1.212  -1.154  -1.228  -1.210  -1.151
236   -        -0.405  -0.400  -0.368  -0.582  -0.587  -0.516  -0.592  -0.583  -0.529
237   -         1.259   1.264   1.280   1.323   1.335   1.354   1.315   1.320   1.338
238   -         1.259   1.264   1.280   1.329   1.335   1.361   1.315   1.320   1.338
239   -         1.259   1.264   1.280   0.940   0.934   0.979   1.315   1.320   1.338
240   -        -0.405  -0.400  -0.368  -0.145  -0.141  -0.087  -0.592  -0.583  -0.529
241   T        -1.378  -1.367  -1.331  -1.314  -1.307  -1.235  -1.228  -1.210  -1.151
242   T        -1.378  -1.367  -1.331  -1.332  -1.314  -1.253  -1.228  -1.210  -1.151
243   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
244   V        -1.378  -1.367  -1.331  -1.244  -1.232  -1.167  -1.228  -1.210  -1.151
245   H         1.259   1.264   1.280   1.557   1.563   1.584   1.315   1.320   1.338
246   E        -0.269  -0.316  -0.329  -0.154  -0.231  -0.266  -0.380  -0.451  -0.468
247   I         1.259   1.264   1.280   1.248   1.263   1.280   1.315   1.320   1.338
248   V        -0.269  -0.224  -0.303  -0.257  -0.180  -0.320  -0.380  -0.311  -0.428
249   E        -1.378  -1.367  -1.331  -1.488  -1.471  -1.406  -1.228  -1.210  -1.151
250   T        -1.378  -1.367  -1.331  -1.308  -1.302  -1.229  -1.228  -1.210  -1.151
251   S        -1.378  -1.367  -1.331  -1.273  -1.270  -1.195  -1.228  -1.210  -1.151
252   R        -1.378  -1.367  -1.331  -1.482  -1.432  -1.401  -1.228  -1.210  -1.151
253   N        -1.378  -1.367  -1.331  -1.357  -1.323  -1.277  -1.228  -1.210  -1.151
254   T        -0.269  -0.224  -0.303  -0.461  -0.377  -0.527  -0.380  -0.311  -0.428
255   S        -0.269  -0.243  -0.307  -0.493  -0.438  -0.556  -0.380  -0.339  -0.435
256   G        -1.378  -1.367  -1.331  -1.354  -1.333  -1.275  -1.228  -1.210  -1.151
257   E        -0.269  -0.224  -0.303  -0.233  -0.169  -0.290  -0.380  -0.311  -0.428
258   E        -0.269  -0.243  -0.307  -0.213  -0.179  -0.273  -0.380  -0.339  -0.435
259   K        -0.269  -0.316  -0.329  -0.203  -0.282  -0.304  -0.380  -0.451  -0.468
260   E        -0.269  -0.316  -0.329  -0.221  -0.307  -0.326  -0.380  -0.451  -0.468
261   Q        -0.269  -0.243  -0.307  -0.243  -0.181  -0.331  -0.380  -0.339  -0.435
262   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   S        -0.269  -0.316  -0.329  -0.106  -0.200  -0.252  -0.380  -0.451  -0.468
268   T        -0.269  -0.243  -0.307  -0.461  -0.410  -0.535  -0.380  -0.339  -0.435
269   W         1.259   1.264   1.280   1.574   1.579   1.600   1.315   1.320   1.338
270   A        -1.378  -1.367  -1.331  -1.338  -1.310  -1.259  -1.228  -1.210  -1.151
271   Y        -0.269  -0.224  -0.303   0.048   0.112  -0.004  -0.380  -0.311  -0.428
272   V        -0.269  -0.316  -0.329  -0.156  -0.229  -0.265  -0.380  -0.451  -0.468
273   E        -1.378  -1.367  -1.331  -1.284  -1.269  -1.206  -1.228  -1.210  -1.151
274   F         1.259   1.264   1.280   1.391   1.409   1.421   1.315   1.320   1.338
275   S         1.259   1.264   1.280   1.100   1.120   1.135   1.315   1.320   1.338
276   A        -1.378  -1.367  -1.331  -1.379  -1.356  -1.299  -1.228  -1.210  -1.151
277   I        -1.378  -1.367  -1.331  -1.448  -1.417  -1.367  -1.228  -1.210  -1.151
278   S         1.259   1.264   1.280   1.100   1.120   1.135   1.315   1.320   1.338
279   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
280   Q        -1.378  -1.367  -1.331  -1.311  -1.272  -1.232  -1.228  -1.210  -1.151
281   N        -0.269  -0.316  -0.329  -0.178  -0.252  -0.276  -0.380  -0.451  -0.468
282   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
283   R        -0.269  -0.316  -0.329  -0.196  -0.264  -0.298  -0.380  -0.451  -0.468
284   I        -1.378  -1.367  -1.331  -1.387  -1.349  -1.307  -1.228  -1.210  -1.151
285   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
286   A         1.259   1.264   1.280   1.331   1.330   1.362   1.315   1.320   1.338
287   M        -0.269  -0.316  -0.329  -0.349  -0.394  -0.413  -0.380  -0.451  -0.468
288   Q        -0.269  -0.224  -0.303  -0.137  -0.054  -0.198  -0.380  -0.311  -0.428
289   T        -1.378  -1.367  -1.331  -1.330  -1.326  -1.251  -1.228  -1.210  -1.151
290   C        -0.269  -0.316  -0.329  -0.438  -0.506  -0.480  -0.380  -0.451  -0.468
291   T        -0.269  -0.224  -0.303  -0.527  -0.450  -0.604  -0.380  -0.311  -0.428
292   S        -0.269  -0.243  -0.307  -0.493  -0.438  -0.556  -0.380  -0.339  -0.435
293   G        -0.269  -0.224  -0.303  -0.308  -0.231  -0.383  -0.380  -0.311  -0.428
294   T        -0.269  -0.243  -0.307  -0.392  -0.346  -0.453  -0.380  -0.339  -0.435
295   K        -1.378  -1.367  -1.331  -1.376  -1.341  -1.296  -1.228  -1.210  -1.151
296   F        -0.269  -0.224  -0.303  -0.071   0.004  -0.120  -0.380  -0.311  -0.428
297   V        -0.269  -0.224  -0.303  -0.257  -0.180  -0.320  -0.380  -0.311  -0.428
298   S        -0.269  -0.224  -0.303  -0.493  -0.407  -0.549  -0.380  -0.311  -0.428
299   T         1.259   1.264   1.280   1.168   1.175   1.202   1.315   1.320   1.338
300   D         1.259   1.264   1.280   1.305   1.307   1.336   1.315   1.320   1.338
301   D         1.259   1.264   1.280   1.305   1.307   1.336   1.315   1.320   1.338
302   I        -1.378  -1.367  -1.331  -1.432  -1.407  -1.351  -1.228  -1.210  -1.151
303   V        -0.269  -0.316  -0.329  -0.555  -0.638  -0.626  -0.380  -0.451  -0.468
304   T         1.259   1.264   1.280   1.168   1.175   1.202   1.315   1.320   1.338
305   A         1.259   1.264   1.280   1.331   1.330   1.362   1.315   1.320   1.338
306   F         1.259   1.264   1.280   1.391   1.409   1.421   1.315   1.320   1.338
307   I        -0.269  -0.316  -0.329  -0.257  -0.337  -0.367  -0.380  -0.451  -0.468
308   W         1.259   1.264   1.280   1.574   1.579   1.600   1.315   1.320   1.338
309   K        -0.269  -0.316  -0.329  -0.137  -0.207  -0.243  -0.380  -0.451  -0.468
310   S        -0.269  -0.243  -0.307  -0.415  -0.367  -0.464  -0.380  -0.339  -0.435
311   V         1.259   1.264   1.280   1.313   1.320   1.345   1.315   1.320   1.338
312   S         1.259   1.264   1.280   1.100   1.120   1.135   1.315   1.320   1.338
313   R         1.259   1.264   1.280   1.331   1.354   1.362   1.315   1.320   1.338
314   A        -0.269  -0.224  -0.303  -0.241  -0.171  -0.305  -0.380  -0.311  -0.428
315   R         1.259   1.264   1.280   1.331   1.354   1.362   1.315   1.320   1.338
316   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
317   S        -0.269  -0.243  -0.307  -0.382  -0.327  -0.425  -0.380  -0.339  -0.435
318   R         1.259   1.264   1.280   1.331   1.354   1.362   1.315   1.320   1.338
319   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
320   K        -1.378  -1.367  -1.331  -1.393  -1.359  -1.312  -1.228  -1.210  -1.151
321   P        -0.269  -0.243  -0.307  -0.203  -0.162  -0.267  -0.380  -0.339  -0.435
322   E        -0.269  -0.316  -0.329  -0.182  -0.268  -0.290  -0.380  -0.451  -0.468
323   T        -0.269  -0.224  -0.303  -0.349  -0.278  -0.396  -0.380  -0.311  -0.428
324   K        -0.269  -0.224  -0.303  -0.178  -0.105  -0.233  -0.380  -0.311  -0.428
325   S        -0.269  -0.316  -0.329  -0.461  -0.542  -0.576  -0.380  -0.451  -0.468
326   N        -0.269  -0.316  -0.329  -0.334  -0.406  -0.417  -0.380  -0.451  -0.468
327   L        -0.269  -0.243  -0.307  -0.587  -0.558  -0.635  -0.380  -0.339  -0.435
328   G        -0.269  -0.224  -0.303  -0.203  -0.143  -0.261  -0.380  -0.311  -0.428
329   R         1.259   1.264   1.280   1.331   1.354   1.362   1.315   1.320   1.338
330   A         1.259   1.264   1.280   1.331   1.330   1.362   1.315   1.320   1.338
331   V        -0.269  -0.243  -0.307  -0.257  -0.211  -0.328  -0.380  -0.339  -0.435
332   D        -0.269  -0.316  -0.329  -0.180  -0.265  -0.288  -0.380  -0.451  -0.468
333   V         1.259   1.264   1.280   1.313   1.320   1.345   1.315   1.320   1.338
334   R         1.259   1.264   1.280   1.331   1.354   1.362   1.315   1.320   1.338
335   K        -0.269  -0.316  -0.329  -0.203  -0.282  -0.304  -0.380  -0.451  -0.468
336   R        -1.378  -1.367  -1.331  -1.008  -0.996  -0.935  -1.228  -1.210  -1.151
337   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
338   G        -0.269  -0.224  -0.303  -0.186  -0.124  -0.241  -0.380  -0.311  -0.428
339   L        -1.378  -1.367  -1.331  -1.531  -1.542  -1.448  -1.228  -1.210  -1.151
340   P        -0.269  -0.243  -0.307  -0.207  -0.160  -0.272  -0.380  -0.339  -0.435
341   E        -1.378  -1.367  -1.331  -1.373  -1.348  -1.293  -1.228  -1.210  -1.151
342   T         1.259   1.264   1.280   1.168   1.175   1.202   1.315   1.320   1.338
343   Y         1.259   1.264   1.280   1.502   1.507   1.530   1.315   1.320   1.338
344   P         1.259   1.264   1.280   1.326   1.332   1.358   1.315   1.320   1.338
345   G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
346   L        -0.269  -0.316  -0.329  -0.241  -0.339  -0.398  -0.380  -0.451  -0.468
347   L        -1.378  -1.367  -1.331  -1.531  -1.542  -1.448  -1.228  -1.210  -1.151
348   V        -1.378  -1.367  -1.331  -1.305  -1.283  -1.227  -1.228  -1.210  -1.151
349   N         1.259   1.264   1.280   1.370   1.376   1.400   1.315   1.320   1.338
350   M         1.259   1.264   1.280   1.468   1.491   1.497   1.315   1.320   1.338
351   T        -0.269  -0.243  -0.307  -0.353  -0.315  -0.407  -0.380  -0.339  -0.435
352   F        -0.269  -0.316  -0.329  -0.021  -0.099  -0.131  -0.380  -0.451  -0.468
353   N        -0.269  -0.243  -0.307  -0.271  -0.220  -0.357  -0.380  -0.339  -0.435
354   T        -1.378  -1.367  -1.331  -1.330  -1.326  -1.251  -1.228  -1.210  -1.151
355   G        -1.378  -1.367  -1.331  -1.179  -1.166  -1.103  -1.228  -1.210  -1.151
356   S        -0.269  -0.316  -0.329  -0.461  -0.542  -0.576  -0.380  -0.451  -0.468
357   L        -0.269  -0.224  -0.303  -0.587  -0.530  -0.629  -0.380  -0.311  -0.428
358   K        -0.269  -0.316  -0.329  -0.411  -0.470  -0.491  -0.380  -0.451  -0.468
359   S        -1.378  -1.367  -1.331  -1.354  -1.344  -1.275  -1.228  -1.210  -1.151
360   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
361   D        -1.378  -1.367  -1.331  -1.365  -1.346  -1.285  -1.228  -1.210  -1.151
362   H        -1.378  -1.367  -1.331  -1.213  -1.179  -1.136  -1.228  -1.210  -1.151
363   K        -1.378  -1.367  -1.331  -1.284  -1.261  -1.206  -1.228  -1.210  -1.151
364   S        -0.269  -0.316  -0.329  -0.312  -0.400  -0.440  -0.380  -0.451  -0.468
365   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
366   G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
367   V        -1.378  -1.367  -1.331  -1.161  -1.145  -1.085  -1.228  -1.210  -1.151
368   L        -1.378  -1.367  -1.331  -1.531  -1.541  -1.448  -1.228  -1.210  -1.151
369   A         1.259   1.264   1.280   1.331   1.330   1.362   1.315   1.320   1.338
370   S         1.259   1.264   1.280   1.100   1.120   1.135   1.315   1.320   1.338
371   Q        -0.269  -0.243  -0.307  -0.123  -0.072  -0.189  -0.380  -0.339  -0.435
372   I        -0.269  -0.316  -0.329  -0.587  -0.670  -0.666  -0.380  -0.451  -0.468
373   R         1.259   1.264   1.280   1.331   1.354   1.362   1.315   1.320   1.338
374   R        -0.269  -0.316  -0.329  -0.415  -0.467  -0.496  -0.380  -0.451  -0.468
375   K        -0.269  -0.224  -0.303  -0.178  -0.105  -0.233  -0.380  -0.311  -0.428
376   L        -0.269  -0.224  -0.303  -0.516  -0.463  -0.546  -0.380  -0.311  -0.428
377   D         1.259   1.264   1.280   1.305   1.307   1.336   1.315   1.320   1.338
378   P        -0.269  -0.243  -0.307  -0.312  -0.262  -0.395  -0.380  -0.339  -0.435
379   K        -0.269  -0.243  -0.307  -0.209  -0.166  -0.277  -0.380  -0.339  -0.435
380   V        -0.405  -0.400  -0.368  -0.527  -0.510  -0.462  -0.592  -0.583  -0.529
381   F        -0.405  -0.400  -0.368  -0.585  -0.573  -0.519  -0.592  -0.583  -0.529
382   D        -1.378  -1.367  -1.331  -1.373  -1.358  -1.293  -1.228  -1.210  -1.151
383   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
384   A        -1.378  -1.367  -1.331  -1.210  -1.199  -1.133  -1.228  -1.210  -1.151
385   Y        -0.269  -0.316  -0.329  -0.063  -0.127  -0.151  -0.380  -0.451  -0.468
386   N        -0.269  -0.224  -0.303  -0.180  -0.110  -0.242  -0.380  -0.311  -0.428
387   T         1.259   1.264   1.280   1.168   1.175   1.202   1.315   1.320   1.338
388   C        -0.269  -0.316  -0.329  -0.104  -0.157  -0.180  -0.380  -0.451  -0.468
389   A         1.259   1.264   1.280   1.331   1.330   1.362   1.315   1.320   1.338
390   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
391   A         1.259   1.264   1.280   1.331   1.330   1.362   1.315   1.320   1.338
392   T         1.259   1.264   1.280   1.168   1.175   1.202   1.315   1.320   1.338
393   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
394   L        -0.269  -0.243  -0.307  -0.587  -0.558  -0.635  -0.380  -0.339  -0.435
395   S        -1.378  -1.367  -1.331  -1.371  -1.364  -1.291  -1.228  -1.210  -1.151
396   R        -1.378  -1.367  -1.331  -1.231  -1.208  -1.154  -1.228  -1.210  -1.151
397   C        -1.378  -1.367  -1.331  -1.179  -1.145  -1.103  -1.228  -1.210  -1.151
398   P        -1.378  -1.367  -1.331  -1.463  -1.446  -1.381  -1.228  -1.210  -1.151
399   D        -1.378  -1.367  -1.331  -1.231  -1.227  -1.154  -1.228  -1.210  -1.151
400   K        -0.269  -0.243  -0.307  -0.269  -0.221  -0.348  -0.380  -0.339  -0.435
401   T        -1.378  -1.367  -1.331  -1.485  -1.463  -1.403  -1.228  -1.210  -1.151
402   K        -0.269  -0.316  -0.329  -0.275  -0.343  -0.369  -0.380  -0.451  -0.468
403   V        -0.269  -0.316  -0.329  -0.361  -0.436  -0.450  -0.380  -0.451  -0.468
404   S         1.259   1.264   1.280   1.100   1.120   1.135   1.315   1.320   1.338
405   I        -1.378  -1.367  -1.331  -1.255  -1.236  -1.177  -1.228  -1.210  -1.151
406   P        -0.269  -0.316  -0.329  -0.355  -0.430  -0.443  -0.380  -0.451  -0.468
407   Q        -0.269  -0.316  -0.329  -0.172  -0.249  -0.266  -0.380  -0.451  -0.468
408   P        -0.269  -0.316  -0.329  -0.355  -0.430  -0.443  -0.380  -0.451  -0.468
409   I        -1.378  -1.367  -1.331  -1.429  -1.398  -1.348  -1.228  -1.210  -1.151
410   D         1.259   1.264   1.280   1.305   1.307   1.336   1.315   1.320   1.338
411   T        -1.378  -1.367  -1.331  -1.215  -1.199  -1.138  -1.228  -1.210  -1.151
412   L        -0.269  -0.316  -0.329  -0.592  -0.684  -0.720  -0.380  -0.451  -0.468
413   S         1.259   1.264   1.280   1.100   1.120   1.135   1.315   1.320   1.338
414   G        -0.269  -0.316  -0.329  -0.227  -0.315  -0.327  -0.380  -0.451  -0.468
415   I         1.259   1.264   1.280   1.248   1.263   1.280   1.315   1.320   1.338
416   M        -0.269  -0.316  -0.329  -0.141  -0.211  -0.226  -0.380  -0.451  -0.468
417   V        -0.269  -0.316  -0.329  -0.555  -0.638  -0.626  -0.380  -0.451  -0.468
418   S         1.259   1.264   1.280   1.100   1.120   1.135   1.315   1.320   1.338
419   S         1.259   1.264   1.280   1.100   1.120   1.135   1.315   1.320   1.338
420   W         1.259   1.264   1.280   1.574   1.579   1.600   1.315   1.320   1.338
421   A        -0.269  -0.224  -0.303  -0.211  -0.147  -0.271  -0.380  -0.311  -0.428
422   K        -0.269  -0.243  -0.307  -0.164  -0.116  -0.224  -0.380  -0.339  -0.435
423   V        -0.269  -0.316  -0.329  -0.148  -0.222  -0.258  -0.380  -0.451  -0.468
424   S        -0.269  -0.316  -0.329  -0.271  -0.360  -0.404  -0.380  -0.451  -0.468
425   L        -1.378  -1.367  -1.331  -1.575  -1.571  -1.492  -1.228  -1.210  -1.151
426   Y         1.259   1.264   1.280   1.502   1.507   1.530   1.315   1.320   1.338
427   D        -1.378  -1.367  -1.331  -1.395  -1.372  -1.315  -1.228  -1.210  -1.151
428   V        -0.269  -0.316  -0.329  -0.555  -0.638  -0.626  -0.380  -0.451  -0.468
429   D         1.259   1.264   1.280   1.305   1.307   1.336   1.315   1.320   1.338
430   F         1.259   1.264   1.280   1.391   1.409   1.421   1.315   1.320   1.338
431   N        -0.269  -0.316  -0.329  -0.186  -0.271  -0.283  -0.380  -0.451  -0.468
432   L        -0.269  -0.224  -0.303  -0.587  -0.530  -0.629  -0.380  -0.311  -0.428
433   G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
434   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
435   G        -0.269  -0.224  -0.303  -0.125  -0.069  -0.170  -0.380  -0.311  -0.428
436   K        -1.378  -1.367  -1.331  -1.434  -1.417  -1.353  -1.228  -1.210  -1.151
437   P         1.259   1.264   1.280   1.326   1.332   1.358   1.315   1.320   1.338
438   K        -0.269  -0.316  -0.329  -0.227  -0.309  -0.325  -0.380  -0.451  -0.468
439   S         1.259   1.264   1.280   1.100   1.120   1.135   1.315   1.320   1.338
440   V         1.259   1.264   1.280   1.313   1.320   1.345   1.315   1.320   1.338
441   R         1.259   1.264   1.280   1.331   1.354   1.362   1.315   1.320   1.338
442   R         1.259   1.264   1.280   1.331   1.354   1.362   1.315   1.320   1.338
443   P         1.259   1.264   1.280   1.326   1.332   1.358   1.315   1.320   1.338
444   R        -1.378  -1.367  -1.331  -1.215  -1.188  -1.138  -1.228  -1.210  -1.151
445   F         1.259   1.264   1.280   1.391   1.409   1.421   1.315   1.320   1.338
446   I        -0.269  -0.316  -0.329  -0.392  -0.467  -0.489  -0.380  -0.451  -0.468
447   S        -0.269  -0.316  -0.329  -0.312  -0.400  -0.440  -0.380  -0.451  -0.468
448   L        -0.269  -0.316  -0.329  -0.388  -0.497  -0.533  -0.380  -0.451  -0.468
449   E         1.259   1.264   1.280   1.300   1.301   1.332   1.315   1.320   1.338
450   S         1.259   1.264   1.280   1.100   1.120   1.135   1.315   1.320   1.338
451   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
452   I        -0.269  -0.316  -0.329  -0.115  -0.186  -0.238  -0.380  -0.451  -0.468
453   Y         1.259   1.264   1.280   1.502   1.507   1.530   1.315   1.320   1.338
454   F        -0.269  -0.224  -0.303  -0.314  -0.224  -0.403  -0.380  -0.311  -0.428
455   M        -0.269  -0.316  -0.329  -0.478  -0.542  -0.529  -0.380  -0.451  -0.468
456   P         1.259   1.264   1.280   1.326   1.332   1.358   1.315   1.320   1.338
457   R        -0.269  -0.316  -0.329  -0.196  -0.264  -0.298  -0.380  -0.451  -0.468
458   S        -0.269  -0.316  -0.329  -0.461  -0.542  -0.576  -0.380  -0.451  -0.468
459   S        -1.378  -1.367  -1.331  -1.376  -1.365  -1.296  -1.228  -1.210  -1.151
460   R        -1.378  -1.367  -1.331  -1.210  -1.183  -1.133  -1.228  -1.210  -1.151
461   G         1.259   1.264   1.280   1.331   1.329   1.362   1.315   1.320   1.338
462   E        -0.269  -0.316  -0.329  -0.241  -0.329  -0.344  -0.380  -0.451  -0.468
463   M        -0.269  -0.316  -0.329  -0.156  -0.219  -0.241  -0.380  -0.451  -0.468
464   V        -0.269  -0.316  -0.329  -0.211  -0.299  -0.315  -0.380  -0.451  -0.468
465   V        -0.269  -0.316  -0.329  -0.555  -0.638  -0.626  -0.380  -0.451  -0.468
466   A         1.259   1.264   1.280   1.331   1.330   1.362   1.315   1.320   1.338
467   L        -0.269  -0.316  -0.329  -0.450  -0.550  -0.590  -0.380  -0.451  -0.468
468   C         1.259   1.264   1.280   1.548   1.554   1.576   1.315   1.320   1.338
469   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
470   R         1.259   1.264   1.280   1.331   1.354   1.362   1.315   1.320   1.338
471   D        -0.269  -0.243  -0.307  -0.241  -0.207  -0.307  -0.380  -0.339  -0.435
472   K        -1.378  -1.367  -1.331  -1.351  -1.328  -1.272  -1.228  -1.210  -1.151
473   D         1.259   1.264   1.280   1.305   1.307   1.336   1.315   1.320   1.338
474   W        -0.269  -0.316  -0.329   0.030  -0.028  -0.057  -0.380  -0.451  -0.468
475   E        -0.269  -0.224  -0.303  -0.336  -0.257  -0.410  -0.380  -0.311  -0.428
476   C        -1.378  -1.367  -1.331  -1.324  -1.292  -1.245  -1.228  -1.210  -1.151
477   L         1.259   1.264   1.280   0.958   0.950   0.996   1.315   1.320   1.338
478   N        -1.378  -1.367  -1.331  -1.210  -1.181  -1.133  -1.228  -1.210  -1.151
479   A        -1.378  -1.367  -1.331  -1.373  -1.344  -1.293  -1.228  -1.210  -1.151
480   D         1.259   1.264   1.280   1.305   1.307   1.336   1.315   1.320   1.338
481   K        -1.378  -1.367  -1.331  -1.252  -1.240  -1.174  -1.228  -1.210  -1.151
482   E        -0.269  -0.224  -0.303  -0.200  -0.132  -0.250  -0.380  -0.311  -0.428
483   W        -1.378  -1.367  -1.331  -0.979  -0.941  -0.906  -1.228  -1.210  -1.151
484   T        -1.378  -1.367  -1.331  -1.303  -1.282  -1.224  -1.228  -1.210  -1.151
485   N        -0.269  -0.316  -0.329  -0.178  -0.252  -0.276  -0.380  -0.451  -0.468
486   Y         1.259   1.264   1.280   1.502   1.507   1.530   1.315   1.320   1.338
487   A         1.259   1.264   1.280   1.331   1.330   1.362   1.315   1.320   1.338
488   T         1.259   1.264   1.280   1.168   1.175   1.202   1.315   1.320   1.338
489   H        -0.269  -0.243  -0.307   0.028   0.074  -0.047  -0.380  -0.339  -0.435
490   I         1.259   1.264   1.280   1.248   1.263   1.280   1.315   1.320   1.338
491   G        -1.378  -1.367  -1.331  -1.357  -1.342  -1.277  -1.228  -1.210  -1.151
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12226
Output conservation file - output/Q12226
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
