1     M         1.541   1.543   1.562   1.922   1.926   1.950   1.629   1.631   1.654
2     S         1.541   1.543   1.562   1.614   1.615   1.643   1.629   1.631   1.654
3     E        -0.005   0.010  -0.042  -0.471  -0.452  -0.508  -0.127  -0.103  -0.184
4     Q        -1.127  -1.125  -1.105  -0.874  -0.866  -0.834  -1.006  -1.002  -0.966
5     E        -0.005  -0.030  -0.054  -0.462  -0.498  -0.511  -0.127  -0.167  -0.204
6     S        -1.127  -1.125  -1.105  -1.147  -1.130  -1.105  -1.006  -1.002  -0.966
7     D        -0.005  -0.030  -0.054  -0.189  -0.245  -0.317  -0.127  -0.167  -0.204
8     E         1.541   1.543   1.562   0.992   0.994   1.023   1.629   1.631   1.654
9     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    K        -0.005  -0.030  -0.054  -0.478  -0.535  -0.596  -0.127  -0.167  -0.204
11    R         1.541   1.543   1.562   1.877   1.880   1.905   1.629   1.631   1.654
12    M        -0.005   0.010  -0.044   0.284   0.307   0.239  -0.127  -0.103  -0.189
13    K        -0.005  -0.030  -0.054  -0.055  -0.084  -0.097  -0.127  -0.167  -0.204
14    Q        -0.005  -0.030  -0.054   0.010  -0.040  -0.097  -0.127  -0.167  -0.204
15    L         1.541   1.543   1.562   1.679   1.682   1.708   1.629   1.631   1.654
16    E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
17    E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
18    A         1.541   1.543   1.562   1.661   1.666   1.690   1.629   1.631   1.654
19    R        -0.005  -0.030  -0.054   0.207   0.155   0.092  -0.127  -0.167  -0.204
20    K        -0.005  -0.030  -0.054  -0.098  -0.129  -0.147  -0.127  -0.167  -0.204
21    R         1.541   1.543   1.562   1.877   1.880   1.905   1.629   1.631   1.654
22    V         1.541   1.543   1.562   1.709   1.709   1.737   1.629   1.631   1.654
23    E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
24    E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
25    L         1.541   1.543   1.562   1.679   1.682   1.708   1.629   1.631   1.654
26    K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
27    K        -0.005   0.010  -0.042  -0.212  -0.187  -0.263  -0.127  -0.103  -0.184
28    K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
31    N         1.541   1.543   1.562   1.559   1.566   1.589   1.629   1.631   1.654
32    K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
33    K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
34    N         1.541   1.543   1.562   1.571   1.574   1.600   1.629   1.631   1.654
35    K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
36    G        -1.127  -1.125  -1.105  -1.000  -1.004  -0.959  -1.006  -1.002  -0.966
37    K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
38    K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
39    N        -1.127  -1.125  -1.105  -1.170  -1.157  -1.129  -1.006  -1.002  -0.966
40    K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
41    N        -0.005  -0.030  -0.054  -0.224  -0.279  -0.352  -0.127  -0.167  -0.204
42    S        -1.127  -1.125  -1.105  -1.135  -1.126  -1.093  -1.006  -1.002  -0.966
43    S        -1.127  -1.125  -1.105  -0.903  -0.896  -0.863  -1.006  -1.002  -0.966
44    A        -1.127  -1.125  -1.105  -1.489  -1.503  -1.446  -1.006  -1.002  -0.966
45    T        -1.127  -1.125  -1.105  -1.289  -1.272  -1.247  -1.006  -1.002  -0.966
46    G        -0.005  -0.030  -0.054   0.339   0.300   0.252  -0.127  -0.167  -0.204
47    S        -1.127  -1.125  -1.105  -1.319  -1.336  -1.276  -1.006  -1.002  -0.966
48    I        -0.143  -0.141  -0.121   0.043   0.045   0.079  -0.347  -0.345  -0.311
49    G        -0.143  -0.141  -0.121  -0.162  -0.160  -0.125  -0.347  -0.345  -0.311
50    S        -1.127  -1.125  -1.105  -0.958  -0.952  -0.918  -1.006  -1.002  -0.966
51    E        -0.005   0.010  -0.042  -0.625  -0.603  -0.684  -0.127  -0.103  -0.184
52    T        -0.005   0.010  -0.042   0.099   0.127   0.044  -0.127  -0.103  -0.184
53    P        -0.143  -0.141  -0.121   0.058   0.060   0.094  -0.347  -0.345  -0.311
54    D        -0.143  -0.141  -0.121  -0.164  -0.161  -0.127  -0.347  -0.345  -0.311
55    L        -0.143  -0.141  -0.121   0.010   0.012   0.046  -0.347  -0.345  -0.311
56    E         1.541   1.543   1.562   1.075   1.078   1.107   1.629   1.631   1.654
57    G        -0.143  -0.141  -0.121   0.022   0.024   0.058  -0.347  -0.345  -0.311
58    T        -0.143  -0.141  -0.121  -0.286  -0.284  -0.248  -0.347  -0.345  -0.311
59    P        -0.143  -0.141  -0.121   0.022   0.024   0.058  -0.347  -0.345  -0.311
60    G        -0.143  -0.141  -0.121   0.046   0.048   0.082  -0.347  -0.345  -0.311
61    E        -0.143  -0.141  -0.121  -0.523  -0.521  -0.484  -0.347  -0.345  -0.311
62    E        -0.005   0.010  -0.042  -0.490  -0.470  -0.530  -0.127  -0.103  -0.184
63    S        -1.127  -1.125  -1.105  -1.323  -1.310  -1.281  -1.006  -1.002  -0.966
64    T        -1.127  -1.125  -1.105  -1.199  -1.216  -1.157  -1.006  -1.002  -0.966
65    Q        -1.127  -1.125  -1.105  -0.874  -0.866  -0.834  -1.006  -1.002  -0.966
66    E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
67    E        -1.127  -1.125  -1.105  -1.115  -1.097  -1.074  -1.006  -1.002  -0.966
68    T         1.541   1.543   1.562   1.590   1.596   1.619   1.629   1.631   1.654
69    V        -1.127  -1.125  -1.105  -1.252  -1.242  -1.210  -1.006  -1.002  -0.966
70    K        -0.005   0.010  -0.044  -0.064  -0.032  -0.147  -0.127  -0.103  -0.189
71    A        -0.005  -0.030  -0.054   0.118   0.079   0.032  -0.127  -0.167  -0.204
72    N        -1.127  -1.125  -1.105  -0.918  -0.908  -0.877  -1.006  -1.002  -0.966
73    S         1.541   1.543   1.562   1.614   1.615   1.643   1.629   1.631   1.654
74    T        -0.005  -0.030  -0.054  -0.195  -0.250  -0.323  -0.127  -0.167  -0.204
75    K        -0.143  -0.141  -0.121  -0.378  -0.376  -0.340  -0.347  -0.345  -0.311
76    S        -0.143  -0.141  -0.121  -0.014  -0.011   0.023  -0.347  -0.345  -0.311
77    E        -0.005  -0.030  -0.054  -0.411  -0.445  -0.452  -0.127  -0.167  -0.204
78    N        -1.127  -1.125  -1.105  -0.708  -0.690  -0.669  -1.006  -1.002  -0.966
79    N        -1.127  -1.125  -1.105  -0.925  -0.920  -0.885  -1.006  -1.002  -0.966
80    D        -0.005   0.010  -0.042  -0.189  -0.155  -0.287  -0.127  -0.103  -0.184
81    Q        -1.127  -1.125  -1.105  -1.203  -1.224  -1.161  -1.006  -1.002  -0.966
82    N        -1.127  -1.125  -1.105  -0.792  -0.788  -0.752  -1.006  -1.002  -0.966
83    D        -0.005  -0.030  -0.054   0.188   0.156   0.129  -0.127  -0.167  -0.204
84    V        -1.127  -1.125  -1.105  -0.767  -0.761  -0.728  -1.006  -1.002  -0.966
85    D        -1.127  -1.125  -1.105  -1.072  -1.060  -1.031  -1.006  -1.002  -0.966
86    E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
87    E        -0.005   0.010  -0.042  -0.436  -0.418  -0.468  -0.127  -0.103  -0.184
88    S        -0.005   0.010  -0.044   0.077   0.104   0.015  -0.127  -0.103  -0.189
89    E        -1.127  -1.125  -1.105  -1.353  -1.357  -1.310  -1.006  -1.002  -0.966
90    E        -0.005   0.010  -0.044  -0.124  -0.090  -0.231  -0.127  -0.103  -0.189
91    K        -0.005   0.010  -0.044  -0.625  -0.603  -0.688  -0.127  -0.103  -0.189
92    E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
93    I        -1.127  -1.125  -1.105  -0.947  -0.958  -0.907  -1.006  -1.002  -0.966
94    E        -1.127  -1.125  -1.105  -1.489  -1.468  -1.446  -1.006  -1.002  -0.966
95    Q        -0.005  -0.030  -0.054  -0.118  -0.178  -0.250  -0.127  -0.167  -0.204
96    V        -1.127  -1.125  -1.105  -0.781  -0.772  -0.742  -1.006  -1.002  -0.966
97    K        -1.127  -1.125  -1.105  -1.567  -1.548  -1.524  -1.006  -1.002  -0.966
98    S        -1.127  -1.125  -1.105  -0.914  -0.907  -0.874  -1.006  -1.002  -0.966
99    D        -0.005   0.010  -0.042  -0.189  -0.155  -0.287  -0.127  -0.103  -0.184
100   P        -1.127  -1.125  -1.105  -1.115  -1.105  -1.074  -1.006  -1.002  -0.966
101   S        -1.127  -1.125  -1.105  -1.007  -1.016  -0.966  -1.006  -1.002  -0.966
102   G        -0.005   0.010  -0.042   0.063   0.098  -0.043  -0.127  -0.103  -0.184
103   T        -0.005  -0.030  -0.054   0.052   0.015  -0.030  -0.127  -0.167  -0.204
104   T        -1.127  -1.125  -1.105  -1.151  -1.138  -1.109  -1.006  -1.002  -0.966
105   E        -1.127  -1.125  -1.105  -1.357  -1.342  -1.315  -1.006  -1.002  -0.966
106   K        -1.127  -1.125  -1.105  -1.170  -1.159  -1.129  -1.006  -1.002  -0.966
107   D        -0.005  -0.030  -0.054  -0.189  -0.245  -0.317  -0.127  -0.167  -0.204
108   I        -1.127  -1.125  -1.105  -1.139  -1.158  -1.097  -1.006  -1.002  -0.966
109   E        -1.127  -1.125  -1.105  -1.485  -1.485  -1.442  -1.006  -1.002  -0.966
110   E        -0.005  -0.030  -0.054  -0.312  -0.339  -0.336  -0.127  -0.167  -0.204
111   I        -0.005   0.010  -0.044  -0.367  -0.352  -0.392  -0.127  -0.103  -0.189
112   N        -1.127  -1.125  -1.105  -1.158  -1.162  -1.117  -1.006  -1.002  -0.966
113   S        -1.127  -1.125  -1.105  -1.239  -1.261  -1.198  -1.006  -1.002  -0.966
114   T        -1.127  -1.125  -1.105  -0.889  -0.886  -0.848  -1.006  -1.002  -0.966
115   S        -1.127  -1.125  -1.105  -0.845  -0.840  -0.805  -1.006  -1.002  -0.966
116   S        -1.127  -1.125  -1.105  -1.319  -1.336  -1.276  -1.006  -1.002  -0.966
117   N        -1.127  -1.125  -1.105  -1.174  -1.175  -1.133  -1.006  -1.002  -0.966
118   V        -1.127  -1.125  -1.105  -1.061  -1.056  -1.019  -1.006  -1.002  -0.966
119   G        -0.005   0.010  -0.044  -0.333  -0.318  -0.354  -0.127  -0.103  -0.189
120   K        -0.005   0.010  -0.042  -0.478  -0.448  -0.568  -0.127  -0.103  -0.184
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   D        -0.005  -0.030  -0.054  -0.189  -0.245  -0.317  -0.127  -0.167  -0.204
132   D        -1.127  -1.125  -1.105  -1.319  -1.306  -1.276  -1.006  -1.002  -0.966
133   A         1.541   1.543   1.562   1.661   1.666   1.690   1.629   1.631   1.654
134   E        -0.005   0.010  -0.042  -0.433  -0.416  -0.465  -0.127  -0.103  -0.184
135   N        -0.005   0.010  -0.042  -0.092  -0.060  -0.170  -0.127  -0.103  -0.184
136   T        -0.005  -0.030  -0.054  -0.064  -0.110  -0.167  -0.127  -0.167  -0.204
137   K         1.541   1.543   1.562   1.332   1.335   1.362   1.629   1.631   1.654
138   K        -1.127  -1.125  -1.105  -1.018  -1.011  -0.978  -1.006  -1.002  -0.966
139   E        -0.005  -0.030  -0.054  -0.462  -0.498  -0.511  -0.127  -0.167  -0.204
140   E        -0.005   0.010  -0.042  -0.471  -0.452  -0.508  -0.127  -0.103  -0.184
141   V         1.541   1.543   1.562   1.738   1.741   1.766   1.629   1.631   1.654
142   Q        -0.005   0.010  -0.044  -0.433  -0.416  -0.467  -0.127  -0.103  -0.189
143   E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
144   V        -0.005   0.010  -0.042   0.215   0.238   0.157  -0.127  -0.103  -0.184
145   I        -1.127  -1.125  -1.105  -0.799  -0.793  -0.759  -1.006  -1.002  -0.966
146   K        -0.143  -0.141  -0.121  -0.138  -0.136  -0.101  -0.347  -0.345  -0.311
147   N        -0.143  -0.141  -0.121  -0.623  -0.620  -0.583  -0.347  -0.345  -0.311
148   N        -0.143  -0.141  -0.121  -0.126  -0.123  -0.089  -0.347  -0.345  -0.311
149   N        -0.143  -0.141  -0.121  -0.623  -0.620  -0.583  -0.347  -0.345  -0.311
150   D        -1.127  -1.125  -1.105  -1.336  -1.349  -1.293  -1.006  -1.002  -0.966
151   E        -0.005   0.010  -0.044  -0.478  -0.448  -0.574  -0.127  -0.103  -0.189
152   Q        -1.127  -1.125  -1.105  -1.223  -1.242  -1.181  -1.006  -1.002  -0.966
153   T        -1.127  -1.125  -1.105  -0.885  -0.877  -0.845  -1.006  -1.002  -0.966
154   A        -1.127  -1.125  -1.105  -0.771  -0.767  -0.731  -1.006  -1.002  -0.966
155   D         1.541   1.543   1.562   1.596   1.601   1.625   1.629   1.631   1.654
156   A        -0.005   0.010  -0.044   0.281   0.309   0.214  -0.127  -0.103  -0.189
157   G        -1.127  -1.125  -1.105  -0.681  -0.671  -0.642  -1.006  -1.002  -0.966
158   K        -1.127  -1.125  -1.105  -1.567  -1.548  -1.524  -1.006  -1.002  -0.966
159   T        -1.127  -1.125  -1.105  -0.988  -0.971  -0.948  -1.006  -1.002  -0.966
160   I        -1.127  -1.125  -1.105  -1.022  -1.015  -0.981  -1.006  -1.002  -0.966
161   E        -0.005   0.010  -0.042  -0.436  -0.418  -0.468  -0.127  -0.103  -0.184
162   P        -1.127  -1.125  -1.105  -1.115  -1.136  -1.074  -1.006  -1.002  -0.966
163   Q        -1.127  -1.125  -1.105  -1.203  -1.190  -1.161  -1.006  -1.002  -0.966
164   E        -0.005  -0.030  -0.054  -0.462  -0.498  -0.511  -0.127  -0.167  -0.204
165   E        -0.005  -0.030  -0.054  -0.625  -0.671  -0.704  -0.127  -0.167  -0.204
166   K        -0.143  -0.141  -0.121  -0.824  -0.822  -0.784  -0.347  -0.345  -0.311
167   K        -0.143  -0.141  -0.121  -0.268  -0.266  -0.231  -0.347  -0.345  -0.311
168   I        -0.143  -0.141  -0.121   0.189   0.192   0.225  -0.347  -0.345  -0.311
169   V        -0.143  -0.141  -0.121  -0.020  -0.018   0.016  -0.347  -0.345  -0.311
170   Q        -1.127  -1.125  -1.105  -0.617  -0.617  -0.578  -1.006  -1.002  -0.966
171   T        -0.005  -0.030  -0.054   0.102   0.066   0.028  -0.127  -0.167  -0.204
172   Q        -0.005   0.010  -0.042   0.140   0.166   0.078  -0.127  -0.103  -0.184
173   E        -0.005   0.010  -0.044  -0.478  -0.448  -0.574  -0.127  -0.103  -0.189
174   G        -1.127  -1.125  -1.105  -1.344  -1.360  -1.302  -1.006  -1.002  -0.966
175   N        -0.005   0.010  -0.044  -0.490  -0.470  -0.533  -0.127  -0.103  -0.189
176   E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
177   P         1.541   1.543   1.562   1.842   1.844   1.870   1.629   1.631   1.654
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   S        -0.143  -0.141  -0.121  -0.103  -0.101  -0.066  -0.347  -0.345  -0.311
181   N        -0.005   0.010  -0.044  -0.212  -0.187  -0.267  -0.127  -0.103  -0.189
182   T        -1.127  -1.125  -1.105  -0.918  -0.912  -0.877  -1.006  -1.002  -0.966
183   S        -1.127  -1.125  -1.105  -0.914  -0.911  -0.874  -1.006  -1.002  -0.966
184   E        -0.005   0.010  -0.044  -0.189  -0.155  -0.293  -0.127  -0.103  -0.189
185   A        -1.127  -1.125  -1.105  -1.107  -1.126  -1.066  -1.006  -1.002  -0.966
186   A        -1.127  -1.125  -1.105  -0.806  -0.801  -0.766  -1.006  -1.002  -0.966
187   D        -0.005  -0.030  -0.054  -0.189  -0.245  -0.317  -0.127  -0.167  -0.204
188   D        -0.005  -0.030  -0.054  -0.189  -0.245  -0.317  -0.127  -0.167  -0.204
189   L        -0.005   0.010  -0.042   0.300   0.322   0.258  -0.127  -0.103  -0.184
190   F         1.541   1.543   1.562   1.894   1.896   1.922   1.629   1.631   1.654
191   A        -0.005   0.010  -0.044   0.339   0.367   0.269  -0.127  -0.103  -0.189
192   N        -0.005  -0.030  -0.054   0.161   0.133   0.104  -0.127  -0.167  -0.204
193   D        -0.005  -0.030  -0.054   0.057   0.020  -0.025  -0.127  -0.167  -0.204
194   G        -0.005   0.010  -0.044   0.194   0.218   0.148  -0.127  -0.103  -0.189
195   N        -0.005  -0.030  -0.054   0.041   0.005  -0.037  -0.127  -0.167  -0.204
196   E        -0.143  -0.141  -0.121  -0.824  -0.822  -0.784  -0.347  -0.345  -0.311
197   E        -0.005   0.010  -0.042  -0.462  -0.445  -0.497  -0.127  -0.103  -0.184
198   S        -1.127  -1.125  -1.105  -1.158  -1.162  -1.117  -1.006  -1.002  -0.966
199   D         1.541   1.543   1.562   1.596   1.601   1.625   1.629   1.631   1.654
200   F         1.541   1.543   1.562   1.894   1.896   1.922   1.629   1.631   1.654
201   L        -0.005   0.010  -0.042   0.239   0.263   0.189  -0.127  -0.103  -0.184
202   T        -0.005   0.010  -0.044   0.088   0.113   0.023  -0.127  -0.103  -0.189
203   T         1.541   1.543   1.562   1.590   1.596   1.619   1.629   1.631   1.654
204   I         1.541   1.543   1.562   1.790   1.794   1.819   1.629   1.631   1.654
205   K        -1.127  -1.125  -1.105  -1.123  -1.109  -1.082  -1.006  -1.002  -0.966
206   K        -0.005  -0.030  -0.054  -0.478  -0.535  -0.596  -0.127  -0.167  -0.204
207   Q        -0.005   0.010  -0.042  -0.118  -0.086  -0.219  -0.127  -0.103  -0.184
208   K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
209   E        -0.005  -0.030  -0.054  -0.462  -0.498  -0.511  -0.127  -0.167  -0.204
210   E        -1.127  -1.125  -1.105  -1.235  -1.221  -1.193  -1.006  -1.002  -0.966
211   D         1.541   1.543   1.562   1.596   1.601   1.625   1.629   1.631   1.654
212   E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
213   L        -1.127  -1.125  -1.105  -0.729  -0.727  -0.690  -1.006  -1.002  -0.966
214   T        -1.127  -1.125  -1.105  -0.838  -0.827  -0.798  -1.006  -1.002  -0.966
215   K        -1.127  -1.125  -1.105  -1.567  -1.548  -1.524  -1.006  -1.002  -0.966
216   L         1.541   1.543   1.562   1.679   1.682   1.708   1.629   1.631   1.654
217   R        -0.005   0.010  -0.044  -0.055  -0.036  -0.087  -0.127  -0.103  -0.189
218   A        -1.127  -1.125  -1.105  -1.489  -1.503  -1.446  -1.006  -1.002  -0.966
219   E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
220   N        -1.127  -1.125  -1.105  -0.799  -0.793  -0.759  -1.006  -1.002  -0.966
221   E        -0.005  -0.030  -0.054  -0.462  -0.498  -0.511  -0.127  -0.167  -0.204
222   K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
223   L         1.541   1.543   1.562   1.679   1.682   1.708   1.629   1.631   1.654
224   T        -1.127  -1.125  -1.105  -1.022  -1.028  -0.981  -1.006  -1.002  -0.966
225   Q        -1.127  -1.125  -1.105  -0.881  -0.877  -0.841  -1.006  -1.002  -0.966
226   E        -0.005  -0.030  -0.054  -0.433  -0.467  -0.478  -0.127  -0.167  -0.204
227   N        -0.005  -0.030  -0.054   0.093   0.059   0.025  -0.127  -0.167  -0.204
228   K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
229   Q        -0.005   0.010  -0.042   0.137   0.164   0.075  -0.127  -0.103  -0.184
230   L         1.541   1.543   1.562   1.679   1.682   1.708   1.629   1.631   1.654
231   K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
232   F         1.541   1.543   1.562   1.894   1.896   1.922   1.629   1.631   1.654
233   L        -1.127  -1.125  -1.105  -0.806  -0.801  -0.766  -1.006  -1.002  -0.966
234   N         1.541   1.543   1.562   1.559   1.566   1.589   1.629   1.631   1.654
235   M        -0.005   0.010  -0.044   0.398   0.421   0.348  -0.127  -0.103  -0.189
236   E        -0.005   0.010  -0.044  -0.189  -0.155  -0.293  -0.127  -0.103  -0.189
237   N        -1.127  -1.125  -1.105  -0.705  -0.702  -0.666  -1.006  -1.002  -0.966
238   E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
239   T        -0.005  -0.030  -0.054   0.077   0.039  -0.001  -0.127  -0.167  -0.204
240   T        -1.127  -1.125  -1.105  -0.889  -0.886  -0.848  -1.006  -1.002  -0.966
241   V        -0.005   0.010  -0.044   0.302   0.327   0.238  -0.127  -0.103  -0.189
242   D        -0.005   0.010  -0.044  -0.471  -0.452  -0.511  -0.127  -0.103  -0.189
243   D        -0.005   0.010  -0.044  -0.471  -0.452  -0.511  -0.127  -0.103  -0.189
244   L         1.541   1.543   1.562   1.679   1.682   1.708   1.629   1.631   1.654
245   Q        -0.005  -0.030  -0.054  -0.118  -0.178  -0.250  -0.127  -0.167  -0.204
246   D        -0.005   0.010  -0.044  -0.471  -0.452  -0.511  -0.127  -0.103  -0.189
247   Q        -0.005   0.010  -0.042  -0.118  -0.086  -0.219  -0.127  -0.103  -0.184
248   L        -1.127  -1.125  -1.105  -0.817  -0.805  -0.777  -1.006  -1.002  -0.966
249   Q        -1.127  -1.125  -1.105  -0.903  -0.899  -0.863  -1.006  -1.002  -0.966
250   E        -1.127  -1.125  -1.105  -1.392  -1.367  -1.349  -1.006  -1.002  -0.966
251   K        -1.127  -1.125  -1.105  -0.691  -0.679  -0.652  -1.006  -1.002  -0.966
252   E        -0.005   0.010  -0.044  -0.478  -0.448  -0.574  -0.127  -0.103  -0.189
253   D        -1.127  -1.125  -1.105  -1.319  -1.306  -1.276  -1.006  -1.002  -0.966
254   I        -1.127  -1.125  -1.105  -0.610  -0.611  -0.571  -1.006  -1.002  -0.966
255   I        -0.005   0.010  -0.044   0.239   0.263   0.185  -0.127  -0.103  -0.189
256   N        -0.005   0.010  -0.042  -0.224  -0.189  -0.322  -0.127  -0.103  -0.184
257   G        -1.127  -1.125  -1.105  -0.757  -0.755  -0.717  -1.006  -1.002  -0.966
258   L        -1.127  -1.125  -1.105  -1.095  -1.100  -1.054  -1.006  -1.002  -0.966
259   Q        -0.005  -0.030  -0.054   0.137   0.097   0.054  -0.127  -0.167  -0.204
260   N        -0.005  -0.030  -0.054   0.093   0.059   0.025  -0.127  -0.167  -0.204
261   D        -0.005  -0.030  -0.054   0.107   0.071   0.033  -0.127  -0.167  -0.204
262   L         1.541   1.543   1.562   1.679   1.682   1.708   1.629   1.631   1.654
263   Q        -0.005  -0.030  -0.054   0.178   0.139   0.101  -0.127  -0.167  -0.204
264   T        -1.127  -1.125  -1.105  -0.914  -0.910  -0.874  -1.006  -1.002  -0.966
265   A        -0.005   0.010  -0.042   0.186   0.211   0.131  -0.127  -0.103  -0.184
266   R        -1.127  -1.125  -1.105  -0.918  -0.912  -0.877  -1.006  -1.002  -0.966
267   D        -1.127  -1.125  -1.105  -0.944  -0.933  -0.903  -1.006  -1.002  -0.966
268   E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
269   L         1.541   1.543   1.562   1.679   1.682   1.708   1.629   1.631   1.654
270   I        -0.143  -0.141  -0.121   0.028   0.030   0.064  -0.347  -0.345  -0.311
271   A        -0.143  -0.141  -0.121  -0.082  -0.080  -0.045  -0.347  -0.345  -0.311
272   A        -1.127  -1.125  -1.105  -0.918  -0.912  -0.877  -1.006  -1.002  -0.966
273   V        -1.127  -1.125  -1.105  -0.856  -0.854  -0.816  -1.006  -1.002  -0.966
274   E        -1.127  -1.125  -1.105  -1.239  -1.232  -1.198  -1.006  -1.002  -0.966
275   K        -0.005  -0.030  -0.054  -0.055  -0.084  -0.097  -0.127  -0.167  -0.204
276   L        -0.005  -0.030  -0.054   0.183   0.144   0.105  -0.127  -0.167  -0.204
277   K        -1.127  -1.125  -1.105  -1.567  -1.578  -1.524  -1.006  -1.002  -0.966
278   L        -1.127  -1.125  -1.105  -1.195  -1.182  -1.153  -1.006  -1.002  -0.966
279   A        -1.127  -1.125  -1.105  -1.207  -1.227  -1.165  -1.006  -1.002  -0.966
280   E        -1.127  -1.125  -1.105  -1.268  -1.256  -1.226  -1.006  -1.002  -0.966
281   A        -1.127  -1.125  -1.105  -0.831  -0.825  -0.791  -1.006  -1.002  -0.966
282   K        -1.127  -1.125  -1.105  -0.985  -0.964  -0.944  -1.006  -1.002  -0.966
283   A        -0.005   0.010  -0.042   0.118   0.148   0.054  -0.127  -0.103  -0.184
284   A        -1.127  -1.125  -1.105  -0.951  -0.942  -0.910  -1.006  -1.002  -0.966
285   R        -1.127  -1.125  -1.105  -0.918  -0.912  -0.877  -1.006  -1.002  -0.966
286   N        -1.127  -1.125  -1.105  -0.824  -0.822  -0.784  -1.006  -1.002  -0.966
287   T        -1.127  -1.125  -1.105  -0.750  -0.741  -0.710  -1.006  -1.002  -0.966
288   T        -1.127  -1.125  -1.105  -0.947  -0.936  -0.907  -1.006  -1.002  -0.966
289   A        -0.005  -0.030  -0.054   0.172   0.135   0.096  -0.127  -0.167  -0.204
290   T        -0.005   0.010  -0.042   0.077   0.104   0.019  -0.127  -0.103  -0.184
291   P         1.541   1.543   1.562   1.842   1.844   1.870   1.629   1.631   1.654
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   I        -1.127  -1.125  -1.105  -0.729  -0.727  -0.690  -1.006  -1.002  -0.966
294   Q        -0.005  -0.030  -0.054  -0.118  -0.178  -0.250  -0.127  -0.167  -0.204
295   F         1.541   1.543   1.562   1.894   1.896   1.922   1.629   1.631   1.654
296   A        -0.005  -0.030  -0.054   0.143   0.103   0.061  -0.127  -0.167  -0.204
297   D        -1.127  -1.125  -1.105  -1.135  -1.126  -1.093  -1.006  -1.002  -0.966
298   F         1.541   1.543   1.562   1.894   1.896   1.922   1.629   1.631   1.654
299   N        -0.005  -0.030  -0.054   0.041   0.005  -0.037  -0.127  -0.167  -0.204
300   T        -1.127  -1.125  -1.105  -0.785  -0.772  -0.745  -1.006  -1.002  -0.966
301   S        -1.127  -1.125  -1.105  -0.736  -0.719  -0.696  -1.006  -1.002  -0.966
302   S         1.541   1.543   1.562   1.614   1.615   1.643   1.629   1.631   1.654
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -0.143  -0.141  -0.121   0.035   0.038   0.072  -0.347  -0.345  -0.311
305   N        -0.005   0.010  -0.044   0.074   0.100   0.007  -0.127  -0.103  -0.189
306   N        -0.005  -0.030  -0.054  -0.092  -0.137  -0.195  -0.127  -0.167  -0.204
307   L        -1.127  -1.125  -1.105  -0.506  -0.500  -0.467  -1.006  -1.002  -0.966
308   T        -1.127  -1.125  -1.105  -1.289  -1.304  -1.247  -1.006  -1.002  -0.966
309   P         1.541   1.543   1.562   1.842   1.844   1.870   1.629   1.631   1.654
310   S         1.541   1.543   1.562   1.614   1.615   1.643   1.629   1.631   1.654
311   Q        -1.127  -1.125  -1.105  -0.771  -0.757  -0.731  -1.006  -1.002  -0.966
312   S        -0.005  -0.030  -0.054   0.123   0.083   0.049  -0.127  -0.167  -0.204
313   V        -1.127  -1.125  -1.105  -0.781  -0.772  -0.742  -1.006  -1.002  -0.966
314   T        -0.143  -0.141  -0.121  -0.045  -0.043  -0.009  -0.347  -0.345  -0.311
315   N        -0.143  -0.141  -0.121  -0.170  -0.168  -0.133  -0.347  -0.345  -0.311
316   S        -0.143  -0.141  -0.121  -0.170  -0.168  -0.133  -0.347  -0.345  -0.311
317   G        -0.143  -0.141  -0.121   0.199   0.202   0.235  -0.347  -0.345  -0.311
318   T        -0.143  -0.141  -0.121  -0.413  -0.411  -0.375  -0.347  -0.345  -0.311
319   Q        -0.143  -0.141  -0.121  -0.033  -0.030   0.004  -0.347  -0.345  -0.311
320   V        -0.143  -0.141  -0.121  -0.126  -0.123  -0.089  -0.347  -0.345  -0.311
321   A        -0.143  -0.141  -0.121  -0.195  -0.193  -0.158  -0.347  -0.345  -0.311
322   H        -0.143  -0.141  -0.121   0.391   0.394   0.426  -0.347  -0.345  -0.311
323   G         1.541   1.543   1.562   1.821   1.824   1.849   1.629   1.631   1.654
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   N        -0.005   0.010  -0.044   0.123   0.151   0.055  -0.127  -0.103  -0.189
327   N        -1.127  -1.125  -1.105  -0.750  -0.730  -0.710  -1.006  -1.002  -0.966
328   M        -1.127  -1.125  -1.105  -0.581  -0.576  -0.542  -1.006  -1.002  -0.966
329   E        -0.005   0.010  -0.044  -0.195  -0.160  -0.299  -0.127  -0.103  -0.189
330   V        -0.005  -0.030  -0.054   0.175   0.132   0.090  -0.127  -0.167  -0.204
331   D         1.541   1.543   1.562   1.596   1.601   1.625   1.629   1.631   1.654
332   R        -0.005  -0.030  -0.054   0.439   0.401   0.365  -0.127  -0.167  -0.204
333   V        -0.005   0.010  -0.042   0.207   0.231   0.148  -0.127  -0.103  -0.184
334   M         1.541   1.543   1.562   1.922   1.926   1.950   1.629   1.631   1.654
335   L         1.541   1.543   1.562   1.679   1.682   1.708   1.629   1.631   1.654
336   N        -1.127  -1.125  -1.105  -0.903  -0.894  -0.863  -1.006  -1.002  -0.966
337   K         1.541   1.543   1.562   1.306   1.308   1.336   1.629   1.631   1.654
338   W         1.541   1.543   1.562   1.962   1.965   1.989   1.629   1.631   1.654
339   R        -0.005  -0.030  -0.054   0.207   0.155   0.092  -0.127  -0.167  -0.204
340   Q        -0.005   0.010  -0.044   0.074   0.102   0.017  -0.127  -0.103  -0.189
341   W         1.541   1.543   1.562   1.962   1.965   1.989   1.629   1.631   1.654
342   N         1.541   1.543   1.562   1.559   1.566   1.589   1.629   1.631   1.654
343   V        -0.005   0.010  -0.042   0.266   0.287   0.214  -0.127  -0.103  -0.184
344   D         1.541   1.543   1.562   1.596   1.601   1.625   1.629   1.631   1.654
345   M         1.541   1.543   1.562   1.922   1.926   1.950   1.629   1.631   1.654
346   T         1.541   1.543   1.562   1.590   1.596   1.619   1.629   1.631   1.654
347   T        -0.005  -0.030  -0.054   0.052   0.015  -0.030  -0.127  -0.167  -0.204
348   W         1.541   1.543   1.562   1.962   1.965   1.989   1.629   1.631   1.654
349   R         1.541   1.543   1.562   1.877   1.880   1.905   1.629   1.631   1.654
350   S         1.541   1.543   1.562   1.614   1.615   1.643   1.629   1.631   1.654
351   I        -0.005  -0.030  -0.054   0.302   0.262   0.222  -0.127  -0.167  -0.204
352   G         1.541   1.543   1.562   1.854   1.859   1.882   1.629   1.631   1.654
353   S        -0.005  -0.030  -0.054   0.143   0.102   0.071  -0.127  -0.167  -0.204
354   G         1.541   1.543   1.562   1.854   1.859   1.882   1.629   1.631   1.654
355   P         1.541   1.543   1.562   1.842   1.844   1.870   1.629   1.631   1.654
356   I        -0.005  -0.030  -0.054   0.302   0.262   0.222  -0.127  -0.167  -0.204
357   M        -0.005   0.010  -0.044   0.326   0.346   0.279  -0.127  -0.103  -0.189
358   E         1.541   1.543   1.562   1.012   1.012   1.044   1.629   1.631   1.654
359   F         1.541   1.543   1.562   1.894   1.896   1.922   1.629   1.631   1.654
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12191
Output conservation file - output/Q12191
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
