1     M         0.807   0.808   0.817   1.019   1.019   1.026   0.829   0.830   0.839
2     H        -0.919  -0.916  -0.865  -0.848  -0.845  -0.760  -1.094  -1.089  -1.003
3     G        -0.919  -0.916  -0.865  -1.017  -1.014  -0.922  -1.094  -1.089  -1.003
4     P        -0.919  -0.916  -0.865  -0.892  -0.889  -0.803  -1.094  -1.089  -1.003
5     T        -0.919  -0.916  -0.865  -0.776  -0.773  -0.691  -1.094  -1.089  -1.003
6     S         0.807   0.808   0.817   0.688   0.694   0.709   0.829   0.830   0.839
7     K        -0.919  -0.916  -0.865  -1.177  -1.164  -1.075  -1.094  -1.089  -1.003
8     A        -0.919  -0.916  -0.865  -1.032  -1.030  -0.936  -1.094  -1.089  -1.003
9     I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    N        -0.919  -0.916  -0.865  -0.939  -0.934  -0.848  -1.094  -1.089  -1.003
13    V         0.807   0.808   0.817   0.785   0.786   0.802   0.829   0.830   0.839
14    R        -0.919  -0.916  -0.865  -1.081  -1.076  -0.983  -1.094  -1.089  -1.003
15    S        -0.919  -0.916  -0.865  -1.081  -1.076  -0.983  -1.094  -1.089  -1.003
16    V        -0.778  -0.751  -0.839  -0.772  -0.729  -0.883  -0.881  -0.841  -0.964
17    K        -0.778  -0.754  -0.838  -1.001  -0.956  -1.087  -0.881  -0.844  -0.962
18    R        -0.778  -0.815  -0.846  -0.873  -0.936  -1.016  -0.881  -0.935  -0.973
19    P        -1.928  -1.921  -1.849  -1.752  -1.750  -1.625  -1.735  -1.725  -1.617
20    R        -1.928  -1.921  -1.849  -2.043  -2.023  -1.903  -1.735  -1.725  -1.617
21    R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
22    A        -0.778  -0.815  -0.846  -0.772  -0.838  -0.895  -0.881  -0.935  -0.973
23    -        -0.919  -0.916  -0.865  -1.033  -1.029  -0.937  -1.094  -1.089  -1.003
24    P         0.807   0.808   0.817   0.954   0.956   0.964   0.829   0.830   0.839
25    R        -1.928  -1.921  -1.849  -1.774  -1.756  -1.646  -1.735  -1.725  -1.617
26    P        -1.928  -1.921  -1.849  -1.823  -1.818  -1.693  -1.735  -1.725  -1.617
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    V        -0.778  -0.815  -0.846  -0.805  -0.868  -0.912  -0.881  -0.935  -0.973
33    V        -0.778  -0.815  -0.846  -0.849  -0.914  -0.969  -0.881  -0.935  -0.973
34    S        -1.928  -1.921  -1.849  -2.031  -2.008  -1.891  -1.735  -1.725  -1.617
35    T        -0.778  -0.751  -0.839  -0.796  -0.754  -0.873  -0.881  -0.841  -0.964
36    Q        -1.928  -1.921  -1.849  -1.898  -1.898  -1.765  -1.735  -1.725  -1.617
37    A         0.807   0.808   0.817   0.843   0.843   0.857   0.829   0.830   0.839
38    M        -0.778  -0.815  -0.846  -0.588  -0.655  -0.727  -0.881  -0.935  -0.973
39    N        -0.778  -0.751  -0.839  -0.869  -0.830  -0.957  -0.881  -0.841  -0.964
40    K        -0.778  -0.815  -0.846  -0.958  -1.010  -1.043  -0.881  -0.935  -0.973
41    L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
42    S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
43    N        -0.778  -0.815  -0.846  -0.860  -0.928  -1.005  -0.881  -0.935  -0.973
44    V        -0.778  -0.815  -0.846  -0.805  -0.868  -0.912  -0.881  -0.935  -0.973
45    T        -1.928  -1.921  -1.849  -1.834  -1.811  -1.704  -1.735  -1.725  -1.617
46    L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
47    S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
48    A        -1.928  -1.921  -1.849  -1.887  -1.880  -1.754  -1.735  -1.725  -1.617
49    E         0.807   0.808   0.817   0.861   0.868   0.875   0.829   0.830   0.839
50    Q         0.807   0.808   0.817   0.945   0.944   0.955   0.829   0.830   0.839
51    E        -1.928  -1.921  -1.849  -1.783  -1.776  -1.654  -1.735  -1.725  -1.617
52    K        -0.778  -0.751  -0.839  -0.751  -0.701  -0.895  -0.881  -0.841  -0.964
53    L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
54    R        -0.778  -0.815  -0.846  -0.873  -0.936  -1.016  -0.881  -0.935  -0.973
55    E        -1.928  -1.921  -1.849  -1.814  -1.801  -1.684  -1.735  -1.725  -1.617
56    R        -0.778  -0.815  -0.846  -0.774  -0.833  -0.886  -0.881  -0.935  -0.973
57    V        -0.778  -0.754  -0.838  -0.805  -0.769  -0.899  -0.881  -0.844  -0.962
58    L        -0.778  -0.815  -0.846  -0.906  -0.961  -0.973  -0.881  -0.935  -0.973
59    S        -1.928  -1.921  -1.849  -1.952  -1.942  -1.816  -1.735  -1.725  -1.617
60    F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
61    M        -0.778  -0.751  -0.839  -0.672  -0.635  -0.751  -0.881  -0.841  -0.964
62    R        -0.778  -0.815  -0.846  -0.873  -0.936  -1.016  -0.881  -0.935  -0.973
63    S        -1.928  -1.921  -1.849  -1.958  -1.953  -1.822  -1.735  -1.725  -1.617
64    N        -0.778  -0.815  -0.846  -0.860  -0.928  -1.005  -0.881  -0.935  -0.973
65    L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
66    S        -1.928  -1.921  -1.849  -1.820  -1.802  -1.690  -1.735  -1.725  -1.617
67    Q        -1.928  -1.921  -1.849  -1.828  -1.818  -1.698  -1.735  -1.725  -1.617
68    Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
69    K        -1.928  -1.921  -1.849  -1.973  -1.963  -1.836  -1.735  -1.725  -1.617
70    S        -0.919  -0.916  -0.865  -1.197  -1.191  -1.094  -1.094  -1.089  -1.003
71    D        -0.919  -0.916  -0.865  -1.071  -1.066  -0.974  -1.094  -1.089  -1.003
72    W        -0.778  -0.751  -0.839  -0.647  -0.611  -0.719  -0.881  -0.841  -0.964
73    K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
74    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    P         0.807   0.808   0.817   0.954   0.956   0.964   0.829   0.830   0.839
76    A        -1.928  -1.921  -1.849  -1.889  -1.883  -1.757  -1.735  -1.725  -1.617
77    M         0.807   0.808   0.817   1.019   1.019   1.026   0.829   0.830   0.839
78    F        -0.778  -0.815  -0.846  -0.636  -0.701  -0.759  -0.881  -0.935  -0.973
79    V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
80    I        -0.778  -0.754  -0.838  -0.781  -0.744  -0.888  -0.881  -0.844  -0.962
81    Q        -0.778  -0.815  -0.846  -0.642  -0.704  -0.768  -0.881  -0.935  -0.973
82    G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
83    D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
84    A         0.807   0.808   0.817   0.843   0.843   0.857   0.829   0.830   0.839
85    G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
86    T         0.807   0.808   0.817   0.936   0.941   0.947   0.829   0.830   0.839
87    G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
88    K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
89    S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
90    V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
91    I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
92    L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
93    N         0.807   0.808   0.817   0.828   0.829   0.844   0.829   0.830   0.839
94    S        -0.778  -0.815  -0.846  -0.840  -0.899  -0.939  -0.881  -0.935  -0.973
95    L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
96    F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
97    N         0.807   0.808   0.817   0.828   0.829   0.844   0.829   0.830   0.839
98    E        -0.778  -0.751  -0.839  -0.853  -0.812  -0.937  -0.881  -0.841  -0.964
99    I        -1.928  -1.921  -1.849  -2.006  -2.006  -1.868  -1.735  -1.725  -1.617
100   Q         0.807   0.808   0.817   0.945   0.944   0.955   0.829   0.830   0.839
101   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
102   L        -0.778  -0.815  -0.846  -0.906  -0.961  -0.973  -0.881  -0.935  -0.973
103   S        -0.778  -0.754  -0.838  -0.840  -0.801  -0.927  -0.881  -0.844  -0.962
104   Q        -1.928  -1.921  -1.849  -1.660  -1.645  -1.537  -1.735  -1.725  -1.617
105   F        -1.928  -1.921  -1.849  -1.619  -1.602  -1.498  -1.735  -1.725  -1.617
106   S        -1.928  -1.921  -1.849  -1.898  -1.885  -1.765  -1.735  -1.725  -1.617
107   P         0.807   0.808   0.817   0.937   0.938   0.947   0.829   0.830   0.839
108   S        -0.778  -0.754  -0.838  -0.900  -0.860  -1.004  -0.881  -0.844  -0.962
109   S        -1.928  -1.921  -1.849  -1.826  -1.811  -1.695  -1.735  -1.725  -1.617
110   E        -1.928  -1.921  -1.849  -1.760  -1.747  -1.633  -1.735  -1.725  -1.617
111   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
112   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
113   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
114   H        -0.778  -0.751  -0.839  -0.833  -0.793  -0.875  -0.881  -0.841  -0.964
115   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
116   T         0.807   0.808   0.817   0.936   0.941   0.947   0.829   0.830   0.839
117   H        -0.778  -0.754  -0.838  -0.535  -0.492  -0.668  -0.881  -0.844  -0.962
118   N         0.807   0.808   0.817   0.828   0.829   0.844   0.829   0.830   0.839
119   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
120   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
121   V        -0.778  -0.754  -0.838  -0.805  -0.769  -0.899  -0.881  -0.844  -0.962
122   V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
123   N         0.807   0.808   0.817   0.828   0.829   0.844   0.829   0.830   0.839
124   H         0.807   0.808   0.817   1.087   1.087   1.091   0.829   0.830   0.839
125   P         0.807   0.808   0.817   0.954   0.956   0.964   0.829   0.830   0.839
126   E         0.807   0.808   0.817   0.861   0.868   0.875   0.829   0.830   0.839
127   M         0.807   0.808   0.817   1.019   1.019   1.026   0.829   0.830   0.839
128   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
129   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
130   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
131   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
132   I        -0.778  -0.751  -0.839  -0.526  -0.483  -0.661  -0.881  -0.841  -0.964
133   R        -0.778  -0.815  -0.846  -0.723  -0.776  -0.818  -0.881  -0.935  -0.973
134   I        -0.778  -0.754  -0.838  -0.672  -0.639  -0.749  -0.881  -0.844  -0.962
135   S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
136   D        -1.928  -1.921  -1.849  -1.857  -1.842  -1.726  -1.735  -1.725  -1.617
137   S        -0.778  -0.754  -0.838  -0.846  -0.808  -0.935  -0.881  -0.844  -0.962
138   F        -0.778  -0.754  -0.838  -0.636  -0.600  -0.745  -0.881  -0.844  -0.962
139   K        -1.928  -1.921  -1.849  -1.828  -1.802  -1.698  -1.735  -1.725  -1.617
140   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
141   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
142   S        -1.928  -1.921  -1.849  -2.034  -2.025  -1.894  -1.735  -1.725  -1.617
143   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
144   S        -0.778  -0.754  -0.838  -0.840  -0.801  -0.927  -0.881  -0.844  -0.962
145   S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
146   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
147   E         0.807   0.808   0.817   0.861   0.868   0.875   0.829   0.830   0.839
148   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
149   P         0.807   0.808   0.817   0.954   0.956   0.964   0.829   0.830   0.839
150   T         0.807   0.808   0.817   0.936   0.941   0.947   0.829   0.830   0.839
151   S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
152   L        -0.778  -0.815  -0.846  -0.985  -1.047  -1.076  -0.881  -0.935  -0.973
153   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
154   N         0.807   0.808   0.817   0.828   0.829   0.844   0.829   0.830   0.839
155   N        -0.778  -0.815  -0.846  -0.805  -0.871  -0.932  -0.881  -0.935  -0.973
156   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
157   Q        -0.778  -0.815  -0.846  -0.657  -0.723  -0.787  -0.881  -0.935  -0.973
158   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
159   R        -0.778  -0.815  -0.846  -0.727  -0.778  -0.824  -0.881  -0.935  -0.973
160   K        -0.778  -0.815  -0.846  -0.958  -1.010  -1.043  -0.881  -0.935  -0.973
161   V        -1.928  -1.921  -1.849  -1.910  -1.899  -1.776  -1.735  -1.725  -1.617
162   M        -0.778  -0.815  -0.846  -0.539  -0.601  -0.662  -0.881  -0.935  -0.973
163   A        -0.778  -0.815  -0.846  -0.624  -0.675  -0.700  -0.881  -0.935  -0.973
164   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
165   V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
166   V        -0.778  -0.815  -0.846  -0.805  -0.868  -0.912  -0.881  -0.935  -0.973
167   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
168   V        -0.778  -0.754  -0.838  -0.805  -0.769  -0.899  -0.881  -0.844  -0.962
169   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
170   E         0.807   0.808   0.817   0.861   0.868   0.875   0.829   0.830   0.839
171   A         0.807   0.808   0.817   0.843   0.843   0.857   0.829   0.830   0.839
172   H         0.807   0.808   0.817   1.087   1.087   1.091   0.829   0.830   0.839
173   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
174   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
175   A         0.807   0.808   0.817   0.843   0.843   0.857   0.829   0.830   0.839
176   T         0.807   0.808   0.817   0.936   0.941   0.947   0.829   0.830   0.839
177   S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
178   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
179   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
180   A         0.807   0.808   0.817   0.843   0.843   0.857   0.829   0.830   0.839
181   F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
182   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
183   R        -0.778  -0.815  -0.846  -0.873  -0.936  -1.016  -0.881  -0.935  -0.973
184   F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
185   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
186   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
187   E        -0.778  -0.815  -0.846  -0.785  -0.850  -0.920  -0.881  -0.935  -0.973
188   N         0.807   0.808   0.817   0.828   0.829   0.844   0.829   0.830   0.839
189   H         0.807   0.808   0.817   1.087   1.087   1.091   0.829   0.830   0.839
190   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
191   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
192   D        -0.778  -0.754  -0.838  -0.853  -0.816  -0.935  -0.881  -0.844  -0.962
193   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
194   M        -0.778  -0.754  -0.838  -0.685  -0.641  -0.835  -0.881  -0.844  -0.962
195   S        -0.778  -0.751  -0.839  -0.774  -0.724  -0.893  -0.881  -0.841  -0.964
196   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
197   C        -1.928  -1.921  -1.849  -1.721  -1.720  -1.595  -1.735  -1.725  -1.617
198   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
199   V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
200   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
201   V        -0.778  -0.815  -0.846  -0.805  -0.868  -0.912  -0.881  -0.935  -0.973
202   L        -0.778  -0.815  -0.846  -0.985  -1.047  -1.076  -0.881  -0.935  -0.973
203   V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
204   Y        -0.778  -0.815  -0.846  -0.668  -0.727  -0.771  -0.881  -0.935  -0.973
205   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
206   D        -1.928  -1.921  -1.849  -1.887  -1.871  -1.754  -1.735  -1.725  -1.617
207   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
208   Q         0.807   0.808   0.817   0.945   0.944   0.955   0.829   0.830   0.839
209   A        -0.778  -0.815  -0.846  -0.792  -0.858  -0.921  -0.881  -0.935  -0.973
210   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
211   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
212   M         0.807   0.808   0.817   1.019   1.019   1.026   0.829   0.830   0.839
213   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
214   S        -0.778  -0.754  -0.838  -0.716  -0.683  -0.770  -0.881  -0.844  -0.962
215   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
216   W         0.807   0.808   0.817   1.073   1.073   1.078   0.829   0.830   0.839
217   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
218   E        -0.778  -0.815  -0.846  -0.785  -0.850  -0.920  -0.881  -0.935  -0.973
219   G        -1.928  -1.921  -1.849  -1.823  -1.808  -1.693  -1.735  -1.725  -1.617
220   S        -0.778  -0.815  -0.846  -0.853  -0.911  -0.957  -0.881  -0.935  -0.973
221   N        -1.928  -1.921  -1.849  -1.823  -1.810  -1.693  -1.735  -1.725  -1.617
222   N         0.807   0.808   0.817   0.828   0.829   0.844   0.829   0.830   0.839
223   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
224   A        -0.778  -0.815  -0.846  -0.792  -0.858  -0.921  -0.881  -0.935  -0.973
225   T        -0.778  -0.751  -0.839  -0.714  -0.672  -0.803  -0.881  -0.841  -0.964
226   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
227   K        -0.778  -0.751  -0.839  -0.751  -0.701  -0.895  -0.881  -0.841  -0.964
228   D        -1.928  -1.921  -1.849  -1.904  -1.895  -1.771  -1.735  -1.725  -1.617
229   F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
230   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
231   N        -0.778  -0.751  -0.839  -0.869  -0.830  -0.957  -0.881  -0.841  -0.964
232   E        -0.778  -0.815  -0.846  -0.774  -0.836  -0.906  -0.881  -0.935  -0.973
233   I        -0.778  -0.815  -0.846  -0.858  -0.931  -1.004  -0.881  -0.935  -0.973
234   P         0.807   0.808   0.817   0.954   0.956   0.964   0.829   0.830   0.839
235   P        -1.928  -1.921  -1.849  -1.777  -1.769  -1.649  -1.735  -1.725  -1.617
236   K        -1.928  -1.921  -1.849  -2.012  -1.983  -1.874  -1.735  -1.725  -1.617
237   S        -1.928  -1.921  -1.849  -2.034  -2.011  -1.894  -1.735  -1.725  -1.617
238   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
239   D        -1.928  -1.921  -1.849  -2.046  -2.040  -1.906  -1.735  -1.725  -1.617
240   W         0.807   0.808   0.817   1.073   1.073   1.078   0.829   0.830   0.839
241   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
242   T        -0.778  -0.754  -0.838  -0.666  -0.622  -0.779  -0.881  -0.844  -0.962
243   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
244   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
245   Q         0.807   0.808   0.817   0.945   0.944   0.955   0.829   0.830   0.839
246   Q         0.807   0.808   0.817   0.945   0.944   0.955   0.829   0.830   0.839
247   F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
248   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
249   V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
250   A        -0.778  -0.815  -0.846  -0.772  -0.838  -0.895  -0.881  -0.935  -0.973
251   A         0.807   0.808   0.817   0.843   0.843   0.857   0.829   0.830   0.839
252   P        -0.778  -0.815  -0.846  -0.649  -0.713  -0.780  -0.881  -0.935  -0.973
253   Q        -1.928  -1.921  -1.849  -1.823  -1.823  -1.693  -1.735  -1.725  -1.617
254   N        -0.778  -0.751  -0.839  -0.869  -0.830  -0.957  -0.881  -0.841  -0.964
255   V        -0.778  -0.815  -0.846  -0.757  -0.813  -0.849  -0.881  -0.935  -0.973
256   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
257   N        -0.778  -0.751  -0.839  -0.869  -0.830  -0.957  -0.881  -0.841  -0.964
258   W         0.807   0.808   0.817   1.073   1.073   1.078   0.829   0.830   0.839
259   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
260   D        -1.928  -1.921  -1.849  -1.843  -1.826  -1.712  -1.735  -1.725  -1.617
261   Q        -1.928  -1.921  -1.849  -1.834  -1.825  -1.704  -1.735  -1.725  -1.617
262   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
263   S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
264   V        -0.778  -0.815  -0.846  -0.757  -0.813  -0.849  -0.881  -0.935  -0.973
265   A        -0.778  -0.751  -0.839  -0.727  -0.680  -0.832  -0.881  -0.841  -0.964
266   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
267   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
268   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
269   P        -0.778  -0.815  -0.846  -0.744  -0.818  -0.907  -0.881  -0.935  -0.973
270   P        -0.778  -0.754  -0.838  -0.742  -0.695  -0.885  -0.881  -0.844  -0.962
271   I        -1.928  -1.921  -1.849  -1.743  -1.731  -1.617  -1.735  -1.725  -1.617
272   E        -0.778  -0.751  -0.839  -0.634  -0.588  -0.748  -0.881  -0.841  -0.964
273   S        -0.778  -0.751  -0.839  -1.001  -0.952  -1.089  -0.881  -0.841  -0.964
274   V        -0.778  -0.751  -0.839  -0.869  -0.825  -0.966  -0.881  -0.841  -0.964
275   L        -0.919  -0.916  -0.865  -1.188  -1.186  -1.085  -1.094  -1.089  -1.003
276   S        -1.928  -1.921  -1.849  -1.820  -1.802  -1.690  -1.735  -1.725  -1.617
277   K        -0.778  -0.815  -0.846  -1.001  -1.057  -1.099  -0.881  -0.935  -0.973
278   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
279   N        -1.928  -1.921  -1.849  -1.828  -1.810  -1.698  -1.735  -1.725  -1.617
280   A        -0.919  -0.916  -0.865  -1.170  -1.164  -1.068  -1.094  -1.089  -1.003
281   D        -0.919  -0.916  -0.865  -1.076  -1.071  -0.978  -1.094  -1.089  -1.003
282   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   K        -1.928  -1.921  -1.849  -1.952  -1.937  -1.816  -1.735  -1.725  -1.617
289   N        -0.778  -0.751  -0.839  -0.958  -0.912  -1.034  -0.881  -0.841  -0.964
290   F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
291   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
292   F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
293   K        -0.778  -0.754  -0.838  -0.902  -0.863  -0.960  -0.881  -0.844  -0.962
294   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
295   W         0.807   0.808   0.817   1.073   1.073   1.078   0.829   0.830   0.839
296   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
297   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
298   C         0.807   0.808   0.817   1.105   1.106   1.108   0.829   0.830   0.839
299   G        -0.778  -0.754  -0.838  -0.759  -0.723  -0.860  -0.881  -0.844  -0.962
300   A        -0.778  -0.754  -0.838  -0.736  -0.695  -0.834  -0.881  -0.844  -0.962
301   M         0.807   0.808   0.817   1.019   1.019   1.026   0.829   0.830   0.839
302   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
303   E        -1.928  -1.921  -1.849  -1.647  -1.630  -1.524  -1.735  -1.725  -1.617
304   A        -0.778  -0.754  -0.838  -0.846  -0.801  -0.976  -0.881  -0.844  -0.962
305   I        -0.778  -0.751  -0.839  -0.960  -0.922  -1.035  -0.881  -0.841  -0.964
306   K        -0.778  -0.815  -0.846  -0.965  -1.015  -1.051  -0.881  -0.935  -0.973
307   E         0.807   0.808   0.817   0.861   0.868   0.875   0.829   0.830   0.839
308   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
309   D        -0.778  -0.751  -0.839  -0.816  -0.772  -0.933  -0.881  -0.841  -0.964
310   R        -1.928  -1.921  -1.849  -1.904  -1.894  -1.771  -1.735  -1.725  -1.617
311   Q        -1.928  -1.921  -1.849  -1.690  -1.678  -1.566  -1.735  -1.725  -1.617
312   Y        -1.928  -1.921  -1.849  -1.746  -1.740  -1.619  -1.735  -1.725  -1.617
313   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
314   Q         0.807   0.808   0.817   0.945   0.944   0.955   0.829   0.830   0.839
315   C         0.807   0.808   0.817   1.105   1.106   1.108   0.829   0.830   0.839
316   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
317   M         0.807   0.808   0.817   1.019   1.019   1.026   0.829   0.830   0.839
318   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
319   S        -0.778  -0.815  -0.846  -0.840  -0.899  -0.939  -0.881  -0.935  -0.973
320   T         0.807   0.808   0.817   0.936   0.941   0.947   0.829   0.830   0.839
321   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
322   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
323   F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
324   P         0.807   0.808   0.817   0.954   0.956   0.964   0.829   0.830   0.839
325   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
326   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
327   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
328   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
329   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
330   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
331   D        -0.778  -0.754  -0.838  -0.866  -0.832  -0.952  -0.881  -0.844  -0.962
332   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
333   Y        -0.778  -0.815  -0.846  -0.668  -0.727  -0.771  -0.881  -0.935  -0.973
334   V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
335   E        -1.928  -1.921  -1.849  -1.690  -1.673  -1.566  -1.735  -1.725  -1.617
336   C         0.807   0.808   0.817   1.105   1.106   1.108   0.829   0.830   0.839
337   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
338   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
339   N         0.807   0.808   0.817   0.849   0.849   0.864   0.829   0.830   0.839
340   F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
341   K        -0.778  -0.815  -0.846  -0.965  -1.015  -1.051  -0.881  -0.935  -0.973
342   V        -0.778  -0.754  -0.838  -0.906  -0.865  -1.029  -0.881  -0.844  -0.962
343   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
344   W         0.807   0.808   0.817   1.073   1.073   1.078   0.829   0.830   0.839
345   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
346   R        -0.778  -0.754  -0.838  -0.689  -0.650  -0.763  -0.881  -0.844  -0.962
347   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
348   T        -0.778  -0.754  -0.838  -0.659  -0.616  -0.771  -0.881  -0.844  -0.962
349   P         0.807   0.808   0.817   0.954   0.956   0.964   0.829   0.830   0.839
350   R        -0.778  -0.754  -0.838  -0.873  -0.823  -0.999  -0.881  -0.844  -0.962
351   E        -0.778  -0.751  -0.839  -0.736  -0.691  -0.836  -0.881  -0.841  -0.964
352   V        -0.778  -0.751  -0.839  -0.985  -0.945  -1.067  -0.881  -0.841  -0.964
353   T        -0.778  -0.751  -0.839  -0.911  -0.872  -0.971  -0.881  -0.841  -0.964
354   P         0.807   0.808   0.817   0.954   0.956   0.964   0.829   0.830   0.839
355   W         0.807   0.808   0.817   1.073   1.073   1.078   0.829   0.830   0.839
356   S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
357   E         0.807   0.808   0.817   0.861   0.868   0.875   0.829   0.830   0.839
358   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
359   C        -0.778  -0.751  -0.839  -0.607  -0.565  -0.678  -0.881  -0.841  -0.964
360   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
361   T         0.807   0.808   0.817   0.936   0.941   0.947   0.829   0.830   0.839
362   I        -0.778  -0.815  -0.846  -0.706  -0.766  -0.804  -0.881  -0.935  -0.973
363   D        -0.778  -0.815  -0.846  -0.853  -0.911  -0.946  -0.881  -0.935  -0.973
364   E         0.807   0.808   0.817   0.861   0.868   0.875   0.829   0.830   0.839
365   V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
366   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
367   S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
368   V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
369   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
370   T         0.807   0.808   0.817   0.936   0.941   0.947   0.829   0.830   0.839
371   I        -0.778  -0.754  -0.838  -0.781  -0.744  -0.888  -0.881  -0.844  -0.962
372   Q         0.807   0.808   0.817   0.945   0.944   0.955   0.829   0.830   0.839
373   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
374   F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
375   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
376   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
377   N         0.807   0.808   0.817   0.828   0.829   0.844   0.829   0.830   0.839
378   Y        -0.778  -0.815  -0.846  -0.609  -0.662  -0.695  -0.881  -0.935  -0.973
379   A         0.807   0.808   0.817   0.843   0.843   0.857   0.829   0.830   0.839
380   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
381   V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
382   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
383   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
384   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
385   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
386   S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
387   I        -0.778  -0.751  -0.839  -0.805  -0.765  -0.901  -0.881  -0.841  -0.964
388   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
389   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
390   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
391   A        -0.778  -0.754  -0.838  -0.846  -0.801  -0.976  -0.881  -0.844  -0.962
392   A        -0.778  -0.815  -0.846  -0.846  -0.915  -0.993  -0.881  -0.935  -0.973
393   N        -0.778  -0.815  -0.846  -0.714  -0.770  -0.813  -0.881  -0.935  -0.973
394   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
395   C        -0.778  -0.815  -0.846  -0.551  -0.622  -0.715  -0.881  -0.935  -0.973
396   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
397   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
398   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
399   R        -0.778  -0.815  -0.846  -0.873  -0.936  -1.016  -0.881  -0.935  -0.973
400   P         0.807   0.808   0.817   0.954   0.956   0.964   0.829   0.830   0.839
401   E         0.807   0.808   0.817   0.861   0.868   0.875   0.829   0.830   0.839
402   L        -0.778  -0.815  -0.846  -0.906  -0.961  -0.973  -0.881  -0.935  -0.973
403   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
404   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
405   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
406   R        -0.778  -0.751  -0.839  -0.535  -0.488  -0.671  -0.881  -0.841  -0.964
407   A         0.807   0.808   0.817   0.843   0.843   0.857   0.829   0.830   0.839
408   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
409   F         0.807   0.808   0.817   0.945   0.943   0.955   0.829   0.830   0.839
410   T         0.807   0.808   0.817   0.936   0.941   0.947   0.829   0.830   0.839
411   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
412   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
413   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
414   N         0.807   0.808   0.817   0.828   0.829   0.844   0.829   0.830   0.839
415   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
416   H        -1.928  -1.921  -1.849  -1.866  -1.865  -1.734  -1.735  -1.725  -1.617
417   N        -0.778  -0.751  -0.839  -0.869  -0.830  -0.957  -0.881  -0.841  -0.964
418   A        -0.778  -0.815  -0.846  -0.772  -0.838  -0.895  -0.881  -0.935  -0.973
419   E        -0.778  -0.754  -0.838  -0.785  -0.740  -0.904  -0.881  -0.844  -0.962
420   D        -1.928  -1.921  -1.849  -1.979  -1.972  -1.842  -1.735  -1.725  -1.617
421   V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
422   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
423   Q        -0.778  -0.815  -0.846  -0.651  -0.716  -0.779  -0.881  -0.935  -0.973
424   K         0.807   0.808   0.817   0.617   0.624   0.642   0.829   0.830   0.839
425   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
426   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
427   M         0.807   0.808   0.817   1.019   1.019   1.026   0.829   0.830   0.839
428   N         0.807   0.808   0.817   0.828   0.829   0.844   0.829   0.830   0.839
429   S         0.807   0.808   0.817   0.738   0.740   0.757   0.829   0.830   0.839
430   I         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
431   N         0.807   0.808   0.817   0.828   0.829   0.844   0.829   0.830   0.839
432   V         0.807   0.808   0.817   0.781   0.781   0.798   0.829   0.830   0.839
433   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
434   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
435   T         0.807   0.808   0.817   0.936   0.941   0.947   0.829   0.830   0.839
436   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
437   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
438   V        -0.778  -0.754  -0.838  -0.757  -0.720  -0.838  -0.881  -0.844  -0.962
439   R        -0.778  -0.751  -0.839  -0.965  -0.916  -1.042  -0.881  -0.841  -0.964
440   G         0.807   0.808   0.817   0.833   0.832   0.848   0.829   0.830   0.839
441   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
442   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
443   V        -0.778  -0.815  -0.846  -0.805  -0.868  -0.912  -0.881  -0.935  -0.973
444   Y         0.807   0.808   0.817   0.875   0.877   0.889   0.829   0.830   0.839
445   A         0.807   0.808   0.817   0.843   0.843   0.857   0.829   0.830   0.839
446   Y        -0.778  -0.751  -0.839  -0.520  -0.477  -0.648  -0.881  -0.841  -0.964
447   D         0.807   0.808   0.817   0.714   0.712   0.734   0.829   0.830   0.839
448   P         0.807   0.808   0.817   0.954   0.956   0.964   0.829   0.830   0.839
449   E         0.807   0.808   0.817   0.861   0.868   0.875   0.829   0.830   0.839
450   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
451   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
452   E         0.807   0.808   0.817   0.861   0.868   0.875   0.829   0.830   0.839
453   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
454   L         0.807   0.808   0.817   0.612   0.612   0.637   0.829   0.830   0.839
455   L        -1.928  -1.921  -1.849  -1.970  -1.954  -1.833  -1.735  -1.725  -1.617
456   R         0.807   0.808   0.817   0.814   0.820   0.830   0.829   0.830   0.839
457   P        -1.928  -1.921  -1.849  -1.820  -1.810  -1.690  -1.735  -1.725  -1.617
458   S        -0.919  -0.916  -0.865  -1.081  -1.076  -0.983  -1.094  -1.089  -1.003
459   K        -0.919  -0.916  -0.865  -1.071  -1.066  -0.974  -1.094  -1.089  -1.003
460   K        -0.919  -0.916  -0.865  -1.139  -1.133  -1.038  -1.094  -1.089  -1.003
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12179
Output conservation file - output/Q12179
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
