1     M         1.781   1.785   1.796   2.050   2.054   2.074   1.912   1.916   1.932
2     -        -0.084  -0.082  -0.070  -0.170  -0.167  -0.147  -0.268  -0.264  -0.245
3     -         1.781   1.785   1.796   1.732   1.738   1.757   1.912   1.916   1.932
4     -        -0.084  -0.082  -0.070  -0.001   0.002   0.022  -0.268  -0.264  -0.245
5     -        -0.084  -0.082  -0.070  -0.267  -0.264  -0.244  -0.268  -0.264  -0.245
6     -        -0.084  -0.082  -0.070  -0.085  -0.082  -0.062  -0.268  -0.264  -0.245
7     -        -0.084  -0.082  -0.070   0.063   0.066   0.086  -0.268  -0.264  -0.245
8     -        -0.084  -0.082  -0.070  -0.306  -0.303  -0.283  -0.268  -0.264  -0.245
9     -        -0.084  -0.082  -0.070   0.090   0.093   0.113  -0.268  -0.264  -0.245
10    -        -0.084  -0.082  -0.070  -0.189  -0.186  -0.166  -0.268  -0.264  -0.245
11    -         1.781   1.785   1.796   1.447   1.453   1.471   1.912   1.916   1.932
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -         1.781   1.785   1.796   1.639   1.645   1.663   1.912   1.916   1.932
14    -        -0.084  -0.082  -0.070   0.232   0.235   0.255  -0.268  -0.264  -0.245
15    -        -0.084  -0.082  -0.070  -0.189  -0.186  -0.166  -0.268  -0.264  -0.245
16    -        -0.084  -0.082  -0.070  -0.316  -0.313  -0.293  -0.268  -0.264  -0.245
17    -        -0.084  -0.082  -0.070   0.063   0.066   0.086  -0.268  -0.264  -0.245
18    -         1.781   1.785   1.796   1.625   1.631   1.649   1.912   1.916   1.932
19    -        -0.084  -0.082  -0.070  -0.001   0.002   0.022  -0.268  -0.264  -0.245
20    -        -0.084  -0.082  -0.070  -0.218  -0.215  -0.195  -0.268  -0.264  -0.245
21    -        -0.084  -0.082  -0.070  -0.286  -0.284  -0.263  -0.268  -0.264  -0.245
22    -        -0.084  -0.082  -0.070  -0.426  -0.423  -0.403  -0.268  -0.264  -0.245
23    -        -0.084  -0.082  -0.070  -0.477  -0.475  -0.454  -0.268  -0.264  -0.245
24    -        -0.084  -0.082  -0.070  -0.257  -0.254  -0.234  -0.268  -0.264  -0.245
25    -        -0.084  -0.082  -0.070  -0.602  -0.600  -0.580  -0.268  -0.264  -0.245
26    -        -0.084  -0.082  -0.070  -0.385  -0.383  -0.363  -0.268  -0.264  -0.245
27    -         1.781   1.785   1.796   1.447   1.453   1.471   1.912   1.916   1.932
28    -        -0.084  -0.082  -0.070  -0.122  -0.120  -0.100  -0.268  -0.264  -0.245
29    -         1.781   1.785   1.796   1.447   1.453   1.471   1.912   1.916   1.932
30    -         1.781   1.785   1.796   1.639   1.645   1.663   1.912   1.916   1.932
31    -        -0.084  -0.082  -0.070  -0.104  -0.101  -0.081  -0.268  -0.264  -0.245
32    -        -0.084  -0.082  -0.070  -0.416  -0.413  -0.393  -0.268  -0.264  -0.245
33    -         1.781   1.785   1.796   1.625   1.631   1.649   1.912   1.916   1.932
34    S        -1.174  -1.171  -1.161  -1.227  -1.220  -1.205  -0.994  -0.989  -0.971
35    F        -1.174  -1.171  -1.161  -1.238  -1.224  -1.216  -0.994  -0.989  -0.971
36    M        -1.174  -1.171  -1.161  -0.999  -0.989  -0.977  -0.994  -0.989  -0.971
37    D         0.069   0.040   0.013   0.111   0.062   0.027  -0.026  -0.070  -0.113
38    Q         0.069   0.074   0.042   0.027   0.039  -0.030  -0.026  -0.017  -0.067
39    I         0.069   0.040   0.013  -0.088  -0.137  -0.184  -0.026  -0.070  -0.113
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    P        -1.174  -1.171  -1.161  -0.968  -0.956  -0.946  -0.994  -0.989  -0.971
43    G         0.069   0.074   0.042   0.158   0.169   0.105  -0.026  -0.017  -0.067
44    G         0.069   0.040   0.013   0.027  -0.012  -0.052  -0.026  -0.070  -0.113
45    G         0.069   0.040   0.013  -0.080  -0.116  -0.155  -0.026  -0.070  -0.113
46    N        -1.174  -1.171  -1.161  -1.068  -1.071  -1.046  -0.994  -0.989  -0.971
47    Y        -1.174  -1.171  -1.161  -1.138  -1.126  -1.116  -0.994  -0.989  -0.971
48    P        -1.174  -1.171  -1.161  -0.999  -0.990  -0.977  -0.994  -0.989  -0.971
49    K         0.069   0.040   0.013  -0.018  -0.073  -0.123  -0.026  -0.070  -0.113
50    L         0.069   0.040   0.013  -0.224  -0.269  -0.321  -0.026  -0.070  -0.113
51    P        -1.174  -1.171  -1.161  -0.911  -0.904  -0.889  -0.994  -0.989  -0.971
52    V        -1.174  -1.171  -1.161  -0.942  -0.931  -0.920  -0.994  -0.989  -0.971
53    E        -1.174  -1.171  -1.161  -1.341  -1.344  -1.319  -0.994  -0.989  -0.971
54    C         0.069   0.040   0.013   0.291   0.250   0.215  -0.026  -0.070  -0.113
55    L         1.781   1.785   1.796   1.669   1.674   1.693   1.912   1.916   1.932
56    P        -1.174  -1.171  -1.161  -0.786  -0.783  -0.763  -0.994  -0.989  -0.971
57    N         0.069   0.102   0.039   0.139   0.185   0.096  -0.026   0.026  -0.072
58    F        -1.174  -1.171  -1.161  -1.005  -1.002  -0.982  -0.994  -0.989  -0.971
59    P        -1.174  -1.171  -1.161  -1.031  -1.021  -1.009  -0.994  -0.989  -0.971
60    I         0.069   0.074   0.042   0.111   0.121   0.076  -0.026  -0.017  -0.067
61    Q        -0.084  -0.082  -0.070  -0.069  -0.066  -0.046  -0.268  -0.264  -0.245
62    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    T         0.069   0.102   0.039   0.205   0.250   0.164  -0.026   0.026  -0.072
66    F         0.069   0.040   0.013   0.260   0.211   0.164  -0.026  -0.070  -0.113
67    R         0.069   0.040   0.013   0.051   0.001  -0.047  -0.026  -0.070  -0.113
68    G         1.781   1.785   1.796   1.965   1.973   1.990   1.912   1.916   1.932
69    R         0.069   0.040   0.013   0.051   0.001  -0.047  -0.026  -0.070  -0.113
70    N        -1.174  -1.171  -1.161  -1.233  -1.228  -1.210  -0.994  -0.989  -0.971
71    D         0.069   0.040   0.013   0.119   0.071   0.035  -0.026  -0.070  -0.113
72    S        -1.174  -1.171  -1.161  -1.057  -1.061  -1.035  -0.994  -0.989  -0.971
73    H        -1.174  -1.171  -1.161  -0.901  -0.889  -0.879  -0.994  -0.989  -0.971
74    K         0.069   0.040   0.013  -0.018  -0.073  -0.123  -0.026  -0.070  -0.113
75    L         0.069   0.040   0.013  -0.055  -0.106  -0.159  -0.026  -0.070  -0.113
76    K         1.781   1.785   1.796   1.678   1.687   1.702   1.912   1.916   1.932
77    N        -1.174  -1.171  -1.161  -0.911  -0.914  -0.889  -0.994  -0.989  -0.971
78    F         1.781   1.785   1.796   1.888   1.894   1.913   1.912   1.916   1.932
79    I         0.069   0.074   0.042   0.006   0.016  -0.038  -0.026  -0.017  -0.067
80    S         0.069   0.074   0.042  -0.047  -0.035  -0.102  -0.026  -0.017  -0.067
81    E         1.781   1.785   1.796   1.561   1.572   1.585   1.912   1.916   1.932
82    I         1.781   1.785   1.796   1.740   1.748   1.764   1.912   1.916   1.932
83    M         0.069   0.040   0.013   0.059   0.018  -0.014  -0.026  -0.070  -0.113
84    L         0.069   0.102   0.039  -0.072  -0.021  -0.122  -0.026   0.026  -0.072
85    N         0.069   0.040   0.013  -0.002  -0.051  -0.097  -0.026  -0.070  -0.113
86    M         0.069   0.040   0.013   0.178   0.137   0.100  -0.026  -0.070  -0.113
87    S         0.069   0.040   0.013  -0.160  -0.200  -0.247  -0.026  -0.070  -0.113
88    M        -1.174  -1.171  -1.161  -0.999  -0.993  -0.977  -0.994  -0.989  -0.971
89    I         0.069   0.040   0.013   0.115   0.064   0.011  -0.026  -0.070  -0.113
90    S         0.069   0.074   0.042  -0.047  -0.035  -0.102  -0.026  -0.017  -0.067
91    W         0.069   0.040   0.013   0.115   0.078   0.051  -0.026  -0.070  -0.113
92    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    N         0.069   0.074   0.042   0.119   0.122   0.080  -0.026  -0.017  -0.067
94    D         1.781   1.785   1.796   1.957   1.960   1.981   1.912   1.916   1.932
95    A        -1.174  -1.171  -1.161  -1.074  -1.072  -1.051  -0.994  -0.989  -0.971
96    S         0.069   0.040   0.013   0.135   0.087   0.036  -0.026  -0.070  -0.113
97    R         0.069   0.040   0.013  -0.072  -0.123  -0.165  -0.026  -0.070  -0.113
98    I         1.781   1.785   1.796   1.740   1.748   1.764   1.912   1.916   1.932
99    V        -1.174  -1.171  -1.161  -1.005  -0.993  -0.982  -0.994  -0.989  -0.971
100   Y        -1.174  -1.171  -1.161  -1.138  -1.124  -1.116  -0.994  -0.989  -0.971
101   C        -1.174  -1.171  -1.161  -0.881  -0.866  -0.858  -0.994  -0.989  -0.971
102   R         0.069   0.040   0.013   0.202   0.149   0.098  -0.026  -0.070  -0.113
103   R         1.781   1.785   1.796   1.775   1.777   1.799   1.912   1.916   1.932
104   H         0.069   0.040   0.013   0.139   0.094   0.058  -0.026  -0.070  -0.113
105   L         0.069   0.040   0.013   0.233   0.174   0.118  -0.026  -0.070  -0.113
106   L         0.069   0.040   0.013   0.035  -0.021  -0.072  -0.026  -0.070  -0.113
107   N         0.069   0.040   0.013   0.205   0.153   0.102  -0.026  -0.070  -0.113
108   P         0.069   0.040   0.013   0.151   0.104   0.073  -0.026  -0.070  -0.113
109   A         1.781   1.785   1.796   1.880   1.885   1.904   1.912   1.916   1.932
110   A        -1.174  -1.171  -1.161  -1.306  -1.287  -1.284  -0.994  -0.989  -0.971
111   Q        -1.174  -1.171  -1.161  -1.266  -1.247  -1.244  -0.994  -0.989  -0.971
112   W         1.781   1.785   1.796   2.167   2.172   2.191   1.912   1.916   1.932
113   A         0.069   0.040   0.013   0.178   0.130   0.085  -0.026  -0.070  -0.113
114   N         0.069   0.102   0.039   0.139   0.185   0.096  -0.026   0.026  -0.072
115   D        -1.174  -1.171  -1.161  -1.127  -1.119  -1.105  -0.994  -0.989  -0.971
116   F        -1.174  -1.171  -1.161  -0.850  -0.848  -0.828  -0.994  -0.989  -0.971
117   V        -1.174  -1.171  -1.161  -0.984  -0.974  -0.961  -0.994  -0.989  -0.971
118   Q        -1.174  -1.171  -1.161  -0.835  -0.837  -0.813  -0.994  -0.989  -0.971
119   E        -1.174  -1.171  -1.161  -1.295  -1.297  -1.273  -0.994  -0.989  -0.971
120   Q        -1.174  -1.171  -1.161  -1.177  -1.168  -1.155  -0.994  -0.989  -0.971
121   G        -1.174  -1.171  -1.161  -1.249  -1.229  -1.227  -0.994  -0.989  -0.971
122   I        -1.174  -1.171  -1.161  -0.963  -0.968  -0.940  -0.994  -0.989  -0.971
123   L        -1.174  -1.171  -1.161  -1.177  -1.178  -1.155  -0.994  -0.989  -0.971
124   E        -1.174  -1.171  -1.161  -1.177  -1.182  -1.155  -0.994  -0.989  -0.971
125   I         0.069   0.040   0.013  -0.189  -0.232  -0.281  -0.026  -0.070  -0.113
126   T         1.781   1.785   1.796   1.836   1.840   1.861   1.912   1.916   1.932
127   F         1.781   1.785   1.796   1.888   1.894   1.913   1.912   1.916   1.932
128   D         0.069   0.102   0.039   0.240   0.293   0.189  -0.026   0.026  -0.072
129   T         0.069   0.040   0.013   0.151   0.102   0.054  -0.026  -0.070  -0.113
130   F         1.781   1.785   1.796   1.888   1.894   1.913   1.912   1.916   1.932
131   I         0.069   0.102   0.039   0.022   0.075  -0.026  -0.026   0.026  -0.072
132   Q         0.069   0.102   0.039   0.225   0.278   0.181  -0.026   0.026  -0.072
133   G        -1.174  -1.171  -1.161  -0.860  -0.855  -0.838  -0.994  -0.989  -0.971
134   L         1.781   1.785   1.796   1.669   1.674   1.693   1.912   1.916   1.932
135   Y        -1.174  -1.171  -1.161  -1.205  -1.188  -1.182  -0.994  -0.989  -0.971
136   Q        -1.174  -1.171  -1.161  -1.036  -1.033  -1.014  -0.994  -0.989  -0.971
137   H         0.069   0.074   0.042   0.279   0.290   0.233  -0.026  -0.017  -0.067
138   F         1.781   1.785   1.796   1.888   1.894   1.913   1.912   1.916   1.932
139   Y        -1.174  -1.171  -1.161  -0.973  -0.965  -0.951  -0.994  -0.989  -0.971
140   K        -1.174  -1.171  -1.161  -1.249  -1.248  -1.227  -0.994  -0.989  -0.971
141   P        -1.174  -1.171  -1.161  -1.074  -1.062  -1.051  -0.994  -0.989  -0.971
142   P        -1.174  -1.171  -1.161  -0.886  -0.878  -0.863  -0.994  -0.989  -0.971
143   D         1.781   1.785   1.796   1.957   1.960   1.981   1.912   1.916   1.932
144   I        -1.174  -1.171  -1.161  -1.221  -1.214  -1.199  -0.994  -0.989  -0.971
145   N        -1.174  -1.171  -1.161  -0.968  -0.967  -0.946  -0.994  -0.989  -0.971
146   K        -1.174  -1.171  -1.161  -1.015  -1.013  -0.993  -0.994  -0.989  -0.971
147   I         0.069   0.040   0.013   0.107   0.058   0.004  -0.026  -0.070  -0.113
148   F         0.069   0.102   0.039   0.244   0.295   0.201  -0.026   0.026  -0.072
149   N        -1.174  -1.171  -1.161  -1.266  -1.257  -1.244  -0.994  -0.989  -0.971
150   A        -1.174  -1.171  -1.161  -1.057  -1.055  -1.035  -0.994  -0.989  -0.971
151   I         0.069   0.074   0.042  -0.055  -0.046  -0.105  -0.026  -0.017  -0.067
152   T        -1.174  -1.171  -1.161  -1.047  -1.048  -1.024  -0.994  -0.989  -0.971
153   Q         0.069   0.040   0.013   0.083   0.035  -0.007  -0.026  -0.070  -0.113
154   L         1.781   1.785   1.796   1.669   1.674   1.693   1.912   1.916   1.932
155   S        -1.174  -1.171  -1.161  -1.221  -1.213  -1.199  -0.994  -0.989  -0.971
156   E         0.069   0.040   0.013   0.027  -0.027  -0.090  -0.026  -0.070  -0.113
157   A        -1.174  -1.171  -1.161  -1.127  -1.121  -1.105  -0.994  -0.989  -0.971
158   K        -1.174  -1.171  -1.161  -1.111  -1.110  -1.089  -0.994  -0.989  -0.971
159   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   G        -1.174  -1.171  -1.161  -1.117  -1.106  -1.094  -0.994  -0.989  -0.971
161   I         0.069   0.040   0.013   0.240   0.191   0.132  -0.026  -0.070  -0.113
162   E        -1.174  -1.171  -1.161  -1.318  -1.314  -1.296  -0.994  -0.989  -0.971
163   R        -1.174  -1.171  -1.161  -1.272  -1.264  -1.250  -0.994  -0.989  -0.971
164   L        -1.174  -1.171  -1.161  -1.047  -1.053  -1.024  -0.994  -0.989  -0.971
165   N         0.069   0.102   0.039   0.047   0.099  -0.004  -0.026   0.026  -0.072
166   Q        -1.174  -1.171  -1.161  -1.090  -1.083  -1.067  -0.994  -0.989  -0.971
167   R        -1.174  -1.171  -1.161  -1.031  -1.037  -1.009  -0.994  -0.989  -0.971
168   F         1.781   1.785   1.796   1.888   1.894   1.913   1.912   1.916   1.932
169   R        -1.174  -1.171  -1.161  -1.193  -1.185  -1.171  -0.994  -0.989  -0.971
170   K        -1.174  -1.171  -1.161  -1.359  -1.351  -1.336  -0.994  -0.989  -0.971
171   I        -1.174  -1.171  -1.161  -1.193  -1.193  -1.171  -0.994  -0.989  -0.971
172   W         0.069   0.040   0.013   0.115   0.078   0.051  -0.026  -0.070  -0.113
173   D        -1.174  -1.171  -1.161  -1.127  -1.118  -1.105  -0.994  -0.989  -0.971
174   R         0.069   0.040   0.013  -0.064  -0.111  -0.157  -0.026  -0.070  -0.113
175   M         0.069   0.040   0.013   0.059   0.018  -0.014  -0.026  -0.070  -0.113
176   P         1.781   1.785   1.796   2.042   2.045   2.066   1.912   1.916   1.932
177   P        -1.174  -1.171  -1.161  -1.052  -1.035  -1.030  -0.994  -0.989  -0.971
178   D         1.781   1.785   1.796   1.957   1.960   1.981   1.912   1.916   1.932
179   F         0.069   0.074   0.042   0.221   0.228   0.181  -0.026  -0.017  -0.067
180   M         0.069   0.040   0.013   0.256   0.212   0.175  -0.026  -0.070  -0.113
181   T         0.069   0.074   0.042   0.095   0.101   0.049  -0.026  -0.017  -0.067
182   E         1.781   1.785   1.796   1.561   1.572   1.585   1.912   1.916   1.932
183   K         0.069   0.040   0.013  -0.219  -0.263  -0.316  -0.026  -0.070  -0.113
184   A         0.069   0.102   0.039   0.170   0.224   0.121  -0.026   0.026  -0.072
185   A         0.069   0.040   0.013  -0.014  -0.056  -0.100  -0.026  -0.070  -0.113
186   I        -1.174  -1.171  -1.161  -1.106  -1.107  -1.084  -0.994  -0.989  -0.971
187   M        -1.174  -1.171  -1.161  -1.090  -1.076  -1.067  -0.994  -0.989  -0.971
188   T        -1.174  -1.171  -1.161  -1.133  -1.132  -1.111  -0.994  -0.989  -0.971
189   Y         1.781   1.785   1.796   1.974   1.979   1.998   1.912   1.916   1.932
190   T        -1.174  -1.171  -1.161  -1.227  -1.220  -1.205  -0.994  -0.989  -0.971
191   R        -1.174  -1.171  -1.161  -1.122  -1.122  -1.100  -0.994  -0.989  -0.971
192   L        -1.174  -1.171  -1.161  -1.182  -1.185  -1.160  -0.994  -0.989  -0.971
193   L         1.781   1.785   1.796   1.669   1.674   1.693   1.912   1.916   1.932
194   T        -1.174  -1.171  -1.161  -1.079  -1.070  -1.057  -0.994  -0.989  -0.971
195   K         0.069   0.102   0.039   0.063   0.111   0.025  -0.026   0.026  -0.072
196   E        -1.174  -1.171  -1.161  -1.210  -1.204  -1.188  -0.994  -0.989  -0.971
197   T         0.069   0.102   0.039   0.067   0.121   0.012  -0.026   0.026  -0.072
198   Y         0.069   0.040   0.013   0.031  -0.009  -0.048  -0.026  -0.070  -0.113
199   N        -1.174  -1.171  -1.161  -1.255  -1.248  -1.233  -0.994  -0.989  -0.971
200   I        -1.174  -1.171  -1.161  -1.266  -1.252  -1.244  -0.994  -0.989  -0.971
201   V         1.781   1.785   1.796   2.025   2.034   2.049   1.912   1.916   1.932
202   R        -1.174  -1.171  -1.161  -1.106  -1.109  -1.084  -0.994  -0.989  -0.971
203   M        -1.174  -1.171  -1.161  -0.855  -0.848  -0.833  -0.994  -0.989  -0.971
204   H        -1.174  -1.171  -1.161  -1.227  -1.202  -1.205  -0.994  -0.989  -0.971
205   K         0.069   0.102   0.039   0.043   0.094   0.003  -0.026   0.026  -0.072
206   P         1.781   1.785   1.796   2.042   2.045   2.066   1.912   1.916   1.932
207   E        -1.174  -1.171  -1.161  -1.341  -1.340  -1.319  -0.994  -0.989  -0.971
208   T         0.069   0.074   0.042   0.095   0.101   0.049  -0.026  -0.017  -0.067
209   L         1.781   1.785   1.796   1.669   1.674   1.693   1.912   1.916   1.932
210   K        -1.174  -1.171  -1.161  -1.244  -1.237  -1.222  -0.994  -0.989  -0.971
211   D        -1.174  -1.171  -1.161  -1.127  -1.111  -1.105  -0.994  -0.989  -0.971
212   A         1.781   1.785   1.796   1.880   1.885   1.904   1.912   1.916   1.932
213   M        -1.174  -1.171  -1.161  -1.084  -1.069  -1.062  -0.994  -0.989  -0.971
214   E         0.069   0.074   0.042  -0.172  -0.163  -0.214  -0.026  -0.017  -0.067
215   E        -1.174  -1.171  -1.161  -1.261  -1.259  -1.239  -0.994  -0.989  -0.971
216   A         0.069   0.102   0.039   0.135   0.190   0.082  -0.026   0.026  -0.072
217   -        -0.084  -0.082  -0.070  -0.011  -0.008   0.012  -0.268  -0.264  -0.245
218   -        -0.084  -0.082  -0.070  -0.316  -0.313  -0.293  -0.268  -0.264  -0.245
219   Y         1.781   1.785   1.796   1.974   1.979   1.998   1.912   1.916   1.932
220   Q        -1.174  -1.171  -1.161  -1.122  -1.104  -1.100  -0.994  -0.989  -0.971
221   T        -1.174  -1.171  -1.161  -1.020  -1.020  -0.998  -0.994  -0.989  -0.971
222   T        -0.084  -0.082  -0.070  -0.245  -0.242  -0.222  -0.268  -0.264  -0.245
223   A        -0.084  -0.082  -0.070  -0.219  -0.216  -0.196  -0.268  -0.264  -0.245
224   L        -0.084  -0.082  -0.070  -0.288  -0.285  -0.265  -0.268  -0.264  -0.245
225   T        -0.084  -0.082  -0.070  -0.028  -0.025  -0.005  -0.268  -0.264  -0.245
226   E        -0.084  -0.082  -0.070  -0.245  -0.242  -0.222  -0.268  -0.264  -0.245
227   R        -0.084  -0.082  -0.070  -0.236  -0.233  -0.213  -0.268  -0.264  -0.245
228   F         1.781   1.785   1.796   1.883   1.889   1.907   1.912   1.916   1.932
229   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   G         1.781   1.785   1.796   1.917   1.923   1.941   1.912   1.916   1.932
239   D        -0.084  -0.082  -0.070  -0.135  -0.132  -0.112  -0.268  -0.264  -0.245
240   T        -0.084  -0.082  -0.070  -0.202  -0.199  -0.179  -0.268  -0.264  -0.245
241   I        -0.084  -0.082  -0.070  -0.219  -0.216  -0.196  -0.268  -0.264  -0.245
242   I        -0.084  -0.082  -0.070  -0.118  -0.115  -0.095  -0.268  -0.264  -0.245
243   G        -0.084  -0.082  -0.070  -0.168  -0.166  -0.145  -0.268  -0.264  -0.245
244   A        -0.084  -0.082  -0.070  -0.202  -0.199  -0.179  -0.268  -0.264  -0.245
245   T         1.781   1.785   1.796   1.837   1.843   1.861   1.912   1.916   1.932
246   T        -0.084  -0.082  -0.070  -0.028  -0.025  -0.005  -0.268  -0.264  -0.245
247   H        -0.084  -0.082  -0.070  -0.210  -0.208  -0.188  -0.268  -0.264  -0.245
248   L         1.781   1.785   1.796   1.756   1.762   1.780   1.912   1.916   1.932
249   Q        -0.084  -0.082  -0.070  -0.060  -0.057  -0.037  -0.268  -0.264  -0.245
250   E        -0.084  -0.082  -0.070  -0.219  -0.216  -0.196  -0.268  -0.264  -0.245
251   E        -0.084  -0.082  -0.070  -0.279  -0.276  -0.256  -0.268  -0.264  -0.245
252   Y        -0.084  -0.082  -0.070  -0.118  -0.115  -0.095  -0.268  -0.264  -0.245
253   D        -0.084  -0.082  -0.070  -0.160  -0.157  -0.137  -0.268  -0.264  -0.245
254   S        -0.084  -0.082  -0.070  -0.060  -0.057  -0.037  -0.268  -0.264  -0.245
255   D        -0.084  -0.082  -0.070  -0.236  -0.233  -0.213  -0.268  -0.264  -0.245
256   Y        -0.084  -0.082  -0.070   0.101   0.104   0.124  -0.268  -0.264  -0.245
257   D        -0.084  -0.082  -0.070  -0.135  -0.132  -0.112  -0.268  -0.264  -0.245
258   S        -0.084  -0.082  -0.070  -0.262  -0.259  -0.239  -0.268  -0.264  -0.245
259   E        -0.084  -0.082  -0.070  -0.219  -0.216  -0.196  -0.268  -0.264  -0.245
260   D        -0.084  -0.082  -0.070  -0.118  -0.115  -0.095  -0.268  -0.264  -0.245
261   N        -0.084  -0.082  -0.070  -0.135  -0.132  -0.112  -0.268  -0.264  -0.245
262   L        -0.084  -0.082  -0.070  -0.185  -0.182  -0.162  -0.268  -0.264  -0.245
263   T        -0.084  -0.082  -0.070  -0.202  -0.199  -0.179  -0.268  -0.264  -0.245
264   Q        -0.084  -0.082  -0.070  -0.279  -0.276  -0.256  -0.268  -0.264  -0.245
265   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   R         1.781   1.785   1.796   1.768   1.774   1.792   1.912   1.916   1.932
273   T         1.781   1.785   1.796   1.837   1.843   1.861   1.912   1.916   1.932
274   R        -0.084  -0.082  -0.070  -0.143  -0.140  -0.120  -0.268  -0.264  -0.245
275   R        -0.084  -0.082  -0.070  -0.110  -0.107  -0.087  -0.268  -0.264  -0.245
276   S        -0.084  -0.082  -0.070  -0.118  -0.115  -0.095  -0.268  -0.264  -0.245
277   Y        -0.084  -0.082  -0.070  -0.219  -0.216  -0.196  -0.268  -0.264  -0.245
278   N        -0.084  -0.082  -0.070  -0.069  -0.066  -0.046  -0.268  -0.264  -0.245
279   K         1.781   1.785   1.796   1.733   1.739   1.757   1.912   1.916   1.932
280   P        -0.084  -0.082  -0.070  -0.160  -0.157  -0.137  -0.268  -0.264  -0.245
281   M        -0.084  -0.082  -0.070   0.037   0.040   0.060  -0.268  -0.264  -0.245
282   S         1.781   1.785   1.796   1.791   1.797   1.815   1.912   1.916   1.932
283   N        -0.084  -0.082  -0.070  -0.077  -0.074  -0.054  -0.268  -0.264  -0.245
284   H        -0.084  -0.082  -0.070  -0.110  -0.107  -0.087  -0.268  -0.264  -0.245
285   R        -0.084  -0.082  -0.070  -0.296  -0.294  -0.273  -0.268  -0.264  -0.245
286   N        -0.084  -0.082  -0.070  -0.357  -0.355  -0.334  -0.268  -0.264  -0.245
287   R        -0.084  -0.082  -0.070  -0.118  -0.115  -0.095  -0.268  -0.264  -0.245
288   R        -0.084  -0.082  -0.070  -0.177  -0.174  -0.154  -0.268  -0.264  -0.245
289   N        -0.084  -0.082  -0.070  -0.143  -0.140  -0.120  -0.268  -0.264  -0.245
290   N         1.781   1.785   1.796   1.768   1.774   1.792   1.912   1.916   1.932
291   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   K         1.781   1.785   1.796   1.733   1.739   1.757   1.912   1.916   1.932
300   N        -0.084  -0.082  -0.070  -0.279  -0.276  -0.256  -0.268  -0.264  -0.245
301   R        -0.084  -0.082  -0.070  -0.118  -0.115  -0.095  -0.268  -0.264  -0.245
302   L        -0.084  -0.082  -0.070  -0.305  -0.302  -0.282  -0.268  -0.264  -0.245
303   C         1.781   1.785   1.796   2.074   2.081   2.098   1.912   1.916   1.932
304   F        -0.084  -0.082  -0.070  -0.036  -0.033  -0.013  -0.268  -0.264  -0.245
305   Y        -0.084  -0.082  -0.070  -0.118  -0.115  -0.095  -0.268  -0.264  -0.245
306   C         1.781   1.785   1.796   2.074   2.081   2.098   1.912   1.916   1.932
307   K        -0.084  -0.082  -0.070  -0.262  -0.259  -0.239  -0.268  -0.264  -0.245
308   K         1.781   1.785   1.796   1.733   1.739   1.757   1.912   1.916   1.932
309   E         1.781   1.785   1.796   1.627   1.633   1.651   1.912   1.916   1.932
310   G         1.781   1.785   1.796   1.917   1.923   1.941   1.912   1.916   1.932
311   H         1.781   1.785   1.796   1.962   1.969   1.987   1.912   1.916   1.932
312   R        -0.084  -0.082  -0.070  -0.168  -0.166  -0.145  -0.268  -0.264  -0.245
313   L        -0.084  -0.082  -0.070  -0.185  -0.182  -0.162  -0.268  -0.264  -0.245
314   N        -0.084  -0.082  -0.070  -0.236  -0.233  -0.213  -0.268  -0.264  -0.245
315   E        -0.084  -0.082  -0.070  -0.279  -0.276  -0.256  -0.268  -0.264  -0.245
316   C         1.781   1.785   1.796   2.074   2.081   2.098   1.912   1.916   1.932
317   R        -0.084  -0.082  -0.070  -0.262  -0.259  -0.239  -0.268  -0.264  -0.245
318   A        -0.084  -0.082  -0.070  -0.279  -0.276  -0.256  -0.268  -0.264  -0.245
319   R        -0.084  -0.082  -0.070  -0.236  -0.233  -0.213  -0.268  -0.264  -0.245
320   K        -0.084  -0.082  -0.070  -0.202  -0.199  -0.179  -0.268  -0.264  -0.245
321   A        -0.084  -0.082  -0.070  -0.185  -0.182  -0.162  -0.268  -0.264  -0.245
322   S         0.069   0.040   0.013   0.095   0.044  -0.002  -0.026  -0.070  -0.113
323   S        -1.174  -1.171  -1.161  -0.958  -0.952  -0.935  -0.994  -0.989  -0.971
324   N         1.781   1.785   1.796   1.784   1.787   1.808   1.912   1.916   1.932
325   R        -1.174  -1.171  -1.161  -1.015  -1.021  -0.993  -0.994  -0.989  -0.971
326   S         0.069   0.102   0.039   0.006   0.067  -0.051  -0.026   0.026  -0.072
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12173
Output conservation file - output/Q12173
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
