1     M         1.861   1.865   1.891   2.221   2.226   2.267   1.999   2.003   2.037
2     A        -0.999  -0.997  -0.981  -0.794  -0.789  -0.761  -0.897  -0.893  -0.863
3     Q        -0.999  -0.997  -0.981  -0.787  -0.798  -0.754  -0.897  -0.893  -0.863
4     N        -0.999  -0.997  -0.981  -0.692  -0.686  -0.659  -0.897  -0.893  -0.863
5     F         1.861   1.865   1.891   2.123   2.126   2.168   1.999   2.003   2.037
6     G         0.204   0.211   0.175   0.540   0.548   0.502   0.068   0.080   0.019
7     K         0.204   0.231   0.182   0.035   0.092  -0.025   0.068   0.112   0.032
8     I         0.204   0.211   0.175   0.017   0.022  -0.057   0.068   0.080   0.019
9     P        -0.999  -0.997  -0.981  -0.651  -0.653  -0.618  -0.897  -0.893  -0.863
10    S         0.204   0.211   0.175   0.303   0.317   0.256   0.068   0.080   0.019
11    H         1.861   1.865   1.891   2.152   2.156   2.197   1.999   2.003   2.037
12    K         0.204   0.231   0.182  -0.017   0.034  -0.076   0.068   0.112   0.032
13    S        -0.999  -0.997  -0.981  -1.182  -1.177  -1.151  -0.897  -0.893  -0.863
14    Y         0.204   0.178   0.162   0.397   0.358   0.337   0.068   0.026  -0.001
15    V         1.861   1.865   1.891   2.070   2.084   2.115   1.999   2.003   2.037
16    L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
17    S        -0.999  -0.997  -0.981  -0.844  -0.843  -0.812  -0.897  -0.893  -0.863
18    L         0.204   0.178   0.162   0.020  -0.015  -0.018   0.068   0.026  -0.001
19    Y         1.861   1.865   1.891   1.999   2.007   2.044   1.999   2.003   2.037
20    R         1.861   1.865   1.891   1.873   1.868   1.918   1.999   2.003   2.037
21    T        -0.999  -0.997  -0.981  -0.648  -0.648  -0.614  -0.897  -0.893  -0.863
22    V         0.204   0.231   0.182   0.316   0.367   0.284   0.068   0.112   0.032
23    L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
24    R         1.861   1.865   1.891   1.873   1.868   1.918   1.999   2.003   2.037
25    N         1.861   1.865   1.891   1.922   1.928   1.966   1.999   2.003   2.037
26    I         0.204   0.211   0.175   0.262   0.271   0.219   0.068   0.080   0.019
27    P        -0.999  -0.997  -0.981  -0.841  -0.848  -0.808  -0.897  -0.893  -0.863
28    K        -0.999  -0.997  -0.981  -1.154  -1.135  -1.123  -0.897  -0.893  -0.863
29    C         0.057   0.058   0.079   0.222   0.218   0.259  -0.173  -0.171  -0.138
30    C        -0.999  -0.997  -0.981  -0.661  -0.660  -0.628  -0.897  -0.893  -0.863
31    H        -0.999  -0.997  -0.981  -0.692  -0.691  -0.659  -0.897  -0.893  -0.863
32    S         0.204   0.178   0.162   0.330   0.293   0.268   0.068   0.026  -0.001
33    Y        -0.999  -0.997  -0.981  -0.661  -0.658  -0.628  -0.897  -0.893  -0.863
34    A        -0.999  -0.997  -0.981  -0.745  -0.747  -0.712  -0.897  -0.893  -0.863
35    F        -0.999  -0.997  -0.981  -0.951  -0.962  -0.919  -0.897  -0.893  -0.863
36    Q         0.204   0.211   0.175   0.143   0.161   0.064   0.068   0.080   0.019
37    Y        -0.999  -0.997  -0.981  -0.769  -0.773  -0.736  -0.897  -0.893  -0.863
38    E         0.204   0.211   0.175   0.035   0.052  -0.042   0.068   0.080   0.019
39    I        -0.999  -0.997  -0.981  -0.999  -1.015  -0.968  -0.897  -0.893  -0.863
40    K         0.204   0.178   0.162  -0.014  -0.031  -0.051   0.068   0.026  -0.001
41    K         0.204   0.178   0.162  -0.172  -0.195  -0.232   0.068   0.026  -0.001
42    T         0.204   0.211   0.175   0.449   0.462   0.401   0.068   0.080   0.019
43    L         0.204   0.211   0.175  -0.151  -0.147  -0.196   0.068   0.080   0.019
44    S        -0.999  -0.997  -0.981  -0.841  -0.845  -0.808  -0.897  -0.893  -0.863
45    I        -0.999  -0.997  -0.981  -0.884  -0.881  -0.852  -0.897  -0.893  -0.863
46    Q        -0.999  -0.997  -0.981  -0.790  -0.793  -0.758  -0.897  -0.893  -0.863
47    L        -0.999  -0.997  -0.981  -1.003  -0.985  -0.971  -0.897  -0.893  -0.863
48    F         0.204   0.231   0.182   0.270   0.300   0.242   0.068   0.112   0.032
49    K         0.204   0.178   0.162  -0.196  -0.227  -0.260   0.068   0.026  -0.001
50    H         0.204   0.178   0.162   0.431   0.383   0.350   0.068   0.026  -0.001
51    K         0.204   0.178   0.162  -0.196  -0.227  -0.260   0.068   0.026  -0.001
52    H         0.204   0.231   0.182   0.327   0.368   0.299   0.068   0.112   0.032
53    D         0.204   0.178   0.162   0.507   0.461   0.443   0.068   0.026  -0.001
54    K         1.861   1.865   1.891   1.498   1.520   1.541   1.999   2.003   2.037
55    S         0.204   0.178   0.162   0.303   0.264   0.237   0.068   0.026  -0.001
56    S         0.204   0.178   0.162   0.332   0.295   0.271   0.068   0.026  -0.001
57    W         1.861   1.865   1.891   2.232   2.236   2.278   1.999   2.003   2.037
58    S         0.204   0.178   0.162   0.284   0.246   0.215   0.068   0.026  -0.001
59    V         0.204   0.211   0.175   0.343   0.360   0.286   0.068   0.080   0.019
60    Y         0.204   0.178   0.162   0.270   0.220   0.191   0.068   0.026  -0.001
61    T        -0.999  -0.997  -0.981  -0.748  -0.753  -0.715  -0.897  -0.893  -0.863
62    L         0.204   0.211   0.175  -0.160  -0.157  -0.206   0.068   0.080   0.019
63    L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
64    N        -0.999  -0.997  -0.981  -1.198  -1.183  -1.167  -0.897  -0.893  -0.863
65    E         0.204   0.178   0.162   0.319   0.274   0.259   0.068   0.026  -0.001
66    F         0.204   0.231   0.182  -0.035  -0.003  -0.056   0.068   0.112   0.032
67    S         0.204   0.211   0.175   0.058   0.084  -0.020   0.068   0.080   0.019
68    L         0.204   0.178   0.162  -0.020  -0.058  -0.064   0.068   0.026  -0.001
69    L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
70    N         0.204   0.211   0.175   0.234   0.250   0.184   0.068   0.080   0.019
71    N        -0.999  -0.997  -0.981  -1.068  -1.069  -1.037  -0.897  -0.893  -0.863
72    C        -0.999  -0.997  -0.981  -0.928  -0.918  -0.896  -0.897  -0.893  -0.863
73    L         0.204   0.178   0.162  -0.151  -0.199  -0.214   0.068   0.026  -0.001
74    L        -0.999  -0.997  -0.981  -1.076  -1.057  -1.044  -0.897  -0.893  -0.863
75    E        -0.999  -0.997  -0.981  -0.703  -0.702  -0.669  -0.897  -0.893  -0.863
76    G         0.204   0.231   0.182   0.486   0.524   0.452   0.068   0.112   0.032
77    K        -0.999  -0.997  -0.981  -0.992  -0.967  -0.960  -0.897  -0.893  -0.863
78    L        -0.999  -0.997  -0.981  -1.099  -1.089  -1.068  -0.897  -0.893  -0.863
79    Q        -0.999  -0.997  -0.981  -0.884  -0.889  -0.852  -0.897  -0.893  -0.863
80    E        -0.999  -0.997  -0.981  -1.064  -1.070  -1.033  -0.897  -0.893  -0.863
81    I        -0.999  -0.997  -0.981  -1.119  -1.136  -1.088  -0.897  -0.893  -0.863
82    K        -0.999  -0.997  -0.981  -1.053  -1.017  -1.021  -0.897  -0.893  -0.863
83    N         0.204   0.178   0.162   0.276   0.233   0.210   0.068   0.026  -0.001
84    L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
85    -         0.057   0.058   0.079  -0.573  -0.572  -0.540  -0.173  -0.171  -0.138
86    -         0.057   0.058   0.079   0.052   0.055   0.089  -0.173  -0.171  -0.138
87    -         0.057   0.058   0.079  -0.245  -0.243  -0.210  -0.173  -0.171  -0.138
88    -         0.057   0.058   0.079   0.187   0.190   0.224  -0.173  -0.171  -0.138
89    M         0.204   0.178   0.162   0.571   0.525   0.501   0.068   0.026  -0.001
90    K         0.204   0.178   0.162  -0.169  -0.195  -0.228   0.068   0.026  -0.001
91    P        -0.999  -0.997  -0.981  -0.741  -0.739  -0.708  -0.897  -0.893  -0.863
92    L        -0.999  -0.997  -0.981  -1.099  -1.089  -1.068  -0.897  -0.893  -0.863
93    K         1.861   1.865   1.891   1.416   1.425   1.458   1.999   2.003   2.037
94    K         0.204   0.178   0.162  -0.169  -0.195  -0.228   0.068   0.026  -0.001
95    M         0.204   0.231   0.182   0.517   0.555   0.489   0.068   0.112   0.032
96    K         0.204   0.178   0.162  -0.112  -0.134  -0.163   0.068   0.026  -0.001
97    K        -0.999  -0.997  -0.981  -1.084  -1.055  -1.052  -0.897  -0.893  -0.863
98    Q         0.204   0.231   0.182   0.281   0.318   0.248   0.068   0.112   0.032
99    L         0.204   0.178   0.162  -0.047  -0.087  -0.094   0.068   0.026  -0.001
100   K         0.204   0.178   0.162  -0.364  -0.401  -0.454   0.068   0.026  -0.001
101   -         0.057   0.058   0.079   0.169   0.172   0.206  -0.173  -0.171  -0.138
102   -         0.057   0.058   0.079   0.212   0.214   0.249  -0.173  -0.171  -0.138
103   T        -0.999  -0.997  -0.981  -0.984  -0.986  -0.952  -0.897  -0.893  -0.863
104   T        -0.999  -0.997  -0.981  -0.651  -0.654  -0.618  -0.897  -0.893  -0.863
105   K         1.861   1.865   1.891   1.498   1.520   1.541   1.999   2.003   2.037
106   I         0.204   0.178   0.162   0.276   0.228   0.216   0.068   0.026  -0.001
107   L        -0.999  -0.997  -0.981  -1.231  -1.232  -1.200  -0.897  -0.893  -0.863
108   N        -0.999  -0.997  -0.981  -0.812  -0.806  -0.779  -0.897  -0.893  -0.863
109   S        -0.999  -0.997  -0.981  -0.805  -0.798  -0.772  -0.897  -0.893  -0.863
110   L        -0.999  -0.997  -0.981  -1.099  -1.081  -1.068  -0.897  -0.893  -0.863
111   T        -0.999  -0.997  -0.981  -0.737  -0.733  -0.704  -0.897  -0.893  -0.863
112   S        -0.999  -0.997  -0.981  -0.723  -0.711  -0.690  -0.897  -0.893  -0.863
113   L        -0.999  -0.997  -0.981  -1.061  -1.045  -1.029  -0.897  -0.893  -0.863
114   G        -0.999  -0.997  -0.981  -1.076  -1.069  -1.044  -0.897  -0.893  -0.863
115   D         0.204   0.231   0.182   0.314   0.354   0.284   0.068   0.112   0.032
116   V        -0.999  -0.997  -0.981  -0.685  -0.676  -0.652  -0.897  -0.893  -0.863
117   K        -0.999  -0.997  -0.981  -1.003  -0.978  -0.971  -0.897  -0.893  -0.863
118   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   D         1.861   1.865   1.891   2.123   2.124   2.168   1.999   2.003   2.037
121   P        -0.999  -0.997  -0.981  -1.080  -1.073  -1.048  -0.897  -0.893  -0.863
122   E        -0.999  -0.997  -0.981  -0.808  -0.806  -0.776  -0.897  -0.893  -0.863
123   E         0.204   0.231   0.182   0.179   0.212   0.141   0.068   0.112   0.032
124   V        -0.999  -0.997  -0.981  -1.111  -1.114  -1.080  -0.897  -0.893  -0.863
125   R        -0.999  -0.997  -0.981  -0.855  -0.862  -0.823  -0.897  -0.893  -0.863
126   R         0.204   0.178   0.162  -0.017  -0.076  -0.121   0.068   0.026  -0.001
127   F        -0.999  -0.997  -0.981  -1.317  -1.323  -1.287  -0.897  -0.893  -0.863
128   H        -0.999  -0.997  -0.981  -1.049  -1.053  -1.017  -0.897  -0.893  -0.863
129   V        -0.999  -0.997  -0.981  -1.111  -1.114  -1.080  -0.897  -0.893  -0.863
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
140   S        -0.999  -0.997  -0.981  -0.734  -0.726  -0.701  -0.897  -0.893  -0.863
141   A         0.204   0.231   0.182   0.232   0.262   0.199   0.068   0.112   0.032
142   Y         1.861   1.865   1.891   1.999   2.007   2.044   1.999   2.003   2.037
143   I         0.204   0.178   0.162   0.017  -0.047  -0.083   0.068   0.026  -0.001
144   K        -0.999  -0.997  -0.981  -1.377  -1.369  -1.346  -0.897  -0.893  -0.863
145   R         0.204   0.211   0.175  -0.017  -0.006  -0.093   0.068   0.080   0.019
146   K         0.204   0.178   0.162  -0.133  -0.153  -0.187   0.068   0.026  -0.001
147   Q         0.204   0.178   0.162   0.365   0.319   0.293   0.068   0.026  -0.001
148   D        -0.999  -0.997  -0.981  -0.992  -1.000  -0.960  -0.897  -0.893  -0.863
149   L        -0.999  -0.997  -0.981  -1.198  -1.192  -1.167  -0.897  -0.893  -0.863
150   G        -0.999  -0.997  -0.981  -0.710  -0.711  -0.676  -0.897  -0.893  -0.863
151   L         0.204   0.178   0.162  -0.044  -0.084  -0.091   0.068   0.026  -0.001
152   L         0.204   0.178   0.162  -0.047  -0.087  -0.094   0.068   0.026  -0.001
153   P         0.204   0.231   0.182   0.463   0.501   0.429   0.068   0.112   0.032
154   A         0.204   0.231   0.182  -0.112  -0.060  -0.137   0.068   0.112   0.032
155   Y        -0.999  -0.997  -0.981  -0.648  -0.643  -0.614  -0.897  -0.893  -0.863
156   I         1.861   1.865   1.891   1.891   1.890   1.936   1.999   2.003   2.037
157   P         1.861   1.865   1.891   2.099   2.101   2.145   1.999   2.003   2.037
158   K        -0.999  -0.997  -0.981  -1.099  -1.087  -1.068  -0.897  -0.893  -0.863
159   T        -0.999  -0.997  -0.981  -1.080  -1.088  -1.048  -0.897  -0.893  -0.863
160   Y         0.204   0.178   0.162   0.397   0.358   0.337   0.068   0.026  -0.001
161   Q        -0.999  -0.997  -0.981  -1.143  -1.137  -1.111  -0.897  -0.893  -0.863
162   H        -0.999  -0.997  -0.981  -0.675  -0.677  -0.642  -0.897  -0.893  -0.863
163   K         0.204   0.178   0.162  -0.169  -0.195  -0.228   0.068   0.026  -0.001
164   L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
165   L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
166   L         0.204   0.178   0.162  -0.160  -0.210  -0.225   0.068   0.026  -0.001
167   P         1.861   1.865   1.891   2.099   2.101   2.145   1.999   2.003   2.037
168   L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
169   A         1.861   1.865   1.891   2.041   2.042   2.086   1.999   2.003   2.037
170   L         0.204   0.178   0.162  -0.151  -0.199  -0.214   0.068   0.026  -0.001
171   N         0.204   0.231   0.182   0.431   0.478   0.388   0.068   0.112   0.032
172   E         1.861   1.865   1.891   1.928   1.928   1.972   1.999   2.003   2.037
173   H        -0.999  -0.997  -0.981  -1.080  -1.079  -1.048  -0.897  -0.893  -0.863
174   A        -0.999  -0.997  -0.981  -0.710  -0.710  -0.676  -0.897  -0.893  -0.863
175   C         0.204   0.211   0.175   0.517   0.527   0.456   0.068   0.080   0.019
176   L         0.204   0.178   0.162  -0.345  -0.393  -0.439   0.068   0.026  -0.001
177   K        -0.999  -0.997  -0.981  -1.255  -1.242  -1.225  -0.897  -0.893  -0.863
178   L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
179   F        -0.999  -0.997  -0.981  -0.699  -0.700  -0.666  -0.897  -0.893  -0.863
180   H        -0.999  -0.997  -0.981  -0.755  -0.768  -0.722  -0.897  -0.893  -0.863
181   I         1.861   1.865   1.891   1.891   1.890   1.936   1.999   2.003   2.037
182   Q        -0.999  -0.997  -0.981  -0.892  -0.901  -0.859  -0.897  -0.893  -0.863
183   Q        -0.999  -0.997  -0.981  -0.819  -0.815  -0.786  -0.897  -0.893  -0.863
184   K        -0.999  -0.997  -0.981  -1.154  -1.141  -1.123  -0.897  -0.893  -0.863
185   L        -0.999  -0.997  -0.981  -1.064  -1.061  -1.033  -0.897  -0.893  -0.863
186   K         0.204   0.178   0.162  -0.112  -0.134  -0.163   0.068   0.026  -0.001
187   N         0.204   0.231   0.182  -0.172  -0.114  -0.203   0.068   0.112   0.032
188   G         1.861   1.865   1.891   2.105   2.107   2.151   1.999   2.003   2.037
189   P         0.204   0.211   0.175   0.465   0.472   0.419   0.068   0.080   0.019
190   P         0.204   0.211   0.175   0.418   0.428   0.366   0.068   0.080   0.019
191   S        -0.999  -0.997  -0.981  -1.030  -1.028  -0.998  -0.897  -0.893  -0.863
192   A         0.204   0.178   0.162   0.397   0.355   0.330   0.068   0.026  -0.001
193   G        -0.999  -0.997  -0.981  -1.061  -1.046  -1.029  -0.897  -0.893  -0.863
194   L         0.204   0.178   0.162  -0.151  -0.199  -0.214   0.068   0.026  -0.001
195   S         0.204   0.178   0.162   0.248   0.209   0.174   0.068   0.026  -0.001
196   Y         0.204   0.211   0.175   0.383   0.395   0.340   0.068   0.080   0.019
197   T         1.861   1.865   1.891   2.099   2.101   2.145   1.999   2.003   2.037
198   K        -0.999  -0.997  -0.981  -1.003  -0.980  -0.971  -0.897  -0.893  -0.863
199   E         0.204   0.231   0.182   0.332   0.373   0.292   0.068   0.112   0.032
200   G         1.861   1.865   1.891   2.105   2.107   2.151   1.999   2.003   2.037
201   R        -0.999  -0.997  -0.981  -1.154  -1.141  -1.123  -0.897  -0.893  -0.863
202   N        -0.999  -0.997  -0.981  -0.812  -0.806  -0.779  -0.897  -0.893  -0.863
203   Q         0.204   0.231   0.182   0.232   0.263   0.199   0.068   0.112   0.032
204   I         1.861   1.865   1.891   1.891   1.890   1.936   1.999   2.003   2.037
205   W         1.861   1.865   1.891   2.232   2.236   2.278   1.999   2.003   2.037
206   F         1.861   1.865   1.891   2.123   2.126   2.168   1.999   2.003   2.037
207   V         0.204   0.231   0.182   0.262   0.301   0.231   0.068   0.112   0.032
208   R         1.861   1.865   1.891   1.873   1.868   1.918   1.999   2.003   2.037
209   S         1.861   1.865   1.891   1.952   1.962   1.996   1.999   2.003   2.037
210   P         0.204   0.211   0.175   0.517   0.525   0.477   0.068   0.080   0.019
211   I        -0.999  -0.997  -0.981  -1.064  -1.059  -1.033  -0.897  -0.893  -0.863
212   N         1.861   1.865   1.891   1.922   1.928   1.966   1.999   2.003   2.037
213   K         0.204   0.178   0.162  -0.196  -0.227  -0.260   0.068   0.026  -0.001
214   G        -0.999  -0.997  -0.981  -1.111  -1.123  -1.080  -0.897  -0.893  -0.863
215   R        -0.999  -0.997  -0.981  -1.154  -1.142  -1.123  -0.897  -0.893  -0.863
216   Q        -0.999  -0.997  -0.981  -1.154  -1.151  -1.123  -0.897  -0.893  -0.863
217   Q         1.861   1.865   1.891   2.041   2.043   2.086   1.999   2.003   2.037
218   S         1.861   1.865   1.891   1.952   1.962   1.996   1.999   2.003   2.037
219   K         0.204   0.211   0.175  -0.364  -0.336  -0.430   0.068   0.080   0.019
220   K         0.204   0.211   0.175  -0.196  -0.174  -0.241   0.068   0.080   0.019
221   L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
222   G        -0.999  -0.997  -0.981  -0.748  -0.753  -0.715  -0.897  -0.893  -0.863
223   I        -0.999  -0.997  -0.981  -0.844  -0.839  -0.812  -0.897  -0.893  -0.863
224   L         0.204   0.178   0.162  -0.151  -0.199  -0.214   0.068   0.026  -0.001
225   I         1.861   1.865   1.891   1.891   1.890   1.936   1.999   2.003   2.037
226   R        -0.999  -0.997  -0.981  -0.877  -0.886  -0.844  -0.897  -0.893  -0.863
227   K         0.204   0.211   0.175  -0.157  -0.128  -0.197   0.068   0.080   0.019
228   E         0.204   0.178   0.162   0.281   0.233   0.216   0.068   0.026  -0.001
229   R         0.204   0.211   0.175  -0.017  -0.006  -0.093   0.068   0.080   0.019
230   K        -0.999  -0.997  -0.981  -1.499  -1.495  -1.469  -0.897  -0.893  -0.863
231   D         0.204   0.231   0.182   0.270   0.299   0.242   0.068   0.112   0.032
232   S        -0.999  -0.997  -0.981  -0.801  -0.793  -0.768  -0.897  -0.893  -0.863
233   Q         0.204   0.211   0.175   0.160   0.169   0.083   0.068   0.080   0.019
234   K        -0.999  -0.997  -0.981  -1.064  -1.039  -1.033  -0.897  -0.893  -0.863
235   N         0.204   0.211   0.175   0.289   0.306   0.245   0.068   0.080   0.019
236   I        -0.999  -0.997  -0.981  -0.973  -0.989  -0.941  -0.897  -0.893  -0.863
237   D         0.204   0.211   0.175   0.221   0.238   0.140   0.068   0.080   0.019
238   N        -0.999  -0.997  -0.981  -0.988  -0.996  -0.956  -0.897  -0.893  -0.863
239   L        -0.999  -0.997  -0.981  -0.951  -0.930  -0.919  -0.897  -0.893  -0.863
240   N        -0.999  -0.997  -0.981  -0.966  -0.972  -0.934  -0.897  -0.893  -0.863
241   F        -0.999  -0.997  -0.981  -0.794  -0.796  -0.761  -0.897  -0.893  -0.863
242   C         0.204   0.211   0.175   0.367   0.380   0.287   0.068   0.080   0.019
243   E         0.204   0.211   0.175   0.226   0.235   0.174   0.068   0.080   0.019
244   I        -0.999  -0.997  -0.981  -0.936  -0.934  -0.904  -0.897  -0.893  -0.863
245   N         0.204   0.178   0.162   0.029  -0.019  -0.075   0.068   0.026  -0.001
246   A         0.204   0.178   0.162   0.160   0.097   0.055   0.068   0.026  -0.001
247   A        -0.999  -0.997  -0.981  -0.745  -0.740  -0.712  -0.897  -0.893  -0.863
248   W         0.204   0.178   0.162   0.538   0.490   0.460   0.068   0.026  -0.001
249   A         1.861   1.865   1.891   2.041   2.042   2.086   1.999   2.003   2.037
250   L         0.204   0.178   0.162  -0.035  -0.074  -0.081   0.068   0.026  -0.001
251   H         0.204   0.178   0.162   0.483   0.436   0.411   0.068   0.026  -0.001
252   E         1.861   1.865   1.891   1.928   1.928   1.972   1.999   2.003   2.037
253   A         1.861   1.865   1.891   2.041   2.042   2.086   1.999   2.003   2.037
254   I         0.204   0.178   0.162   0.248   0.199   0.184   0.068   0.026  -0.001
255   W         1.861   1.865   1.891   2.232   2.236   2.278   1.999   2.003   2.037
256   E         1.861   1.865   1.891   1.928   1.928   1.972   1.999   2.003   2.037
257   E        -0.999  -0.997  -0.981  -0.917  -0.918  -0.885  -0.897  -0.893  -0.863
258   Y         0.204   0.178   0.162   0.373   0.332   0.309   0.068   0.026  -0.001
259   L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
260   E         0.057   0.058   0.079   0.151   0.152   0.188  -0.173  -0.171  -0.138
261   S         0.057   0.058   0.079   0.114   0.114   0.151  -0.173  -0.171  -0.138
262   K         0.057   0.058   0.079  -0.239  -0.235  -0.204  -0.173  -0.171  -0.138
263   K         0.057   0.058   0.079  -0.329  -0.319  -0.294  -0.173  -0.171  -0.138
264   I         0.204   0.211   0.175   0.017   0.022  -0.057   0.068   0.080   0.019
265   I         0.204   0.231   0.182   0.418   0.462   0.373   0.068   0.112   0.032
266   K         0.204   0.211   0.175  -0.112  -0.088  -0.147   0.068   0.080   0.019
267   V        -0.999  -0.997  -0.981  -0.672  -0.668  -0.638  -0.897  -0.893  -0.863
268   N        -0.999  -0.997  -0.981  -0.812  -0.801  -0.779  -0.897  -0.893  -0.863
269   L        -0.999  -0.997  -0.981  -0.936  -0.911  -0.904  -0.897  -0.893  -0.863
270   P        -0.999  -0.997  -0.981  -1.064  -1.050  -1.033  -0.897  -0.893  -0.863
271   K        -0.999  -0.997  -0.981  -1.111  -1.098  -1.080  -0.897  -0.893  -0.863
272   Y         0.204   0.178   0.162   0.103   0.055  -0.003   0.068   0.026  -0.001
273   L         0.204   0.178   0.162  -0.035  -0.074  -0.081   0.068   0.026  -0.001
274   E        -0.999  -0.997  -0.981  -1.198  -1.183  -1.167  -0.897  -0.893  -0.863
275   Y        -0.999  -0.997  -0.981  -0.593  -0.589  -0.560  -0.897  -0.893  -0.863
276   A         0.204   0.231   0.182   0.410   0.460   0.374   0.068   0.112   0.032
277   A        -0.999  -0.997  -0.981  -0.773  -0.767  -0.740  -0.897  -0.893  -0.863
278   N        -0.999  -0.997  -0.981  -0.848  -0.844  -0.815  -0.897  -0.893  -0.863
279   I        -0.999  -0.997  -0.981  -0.881  -0.881  -0.848  -0.897  -0.893  -0.863
280   P        -0.999  -0.997  -0.981  -0.727  -0.738  -0.694  -0.897  -0.893  -0.863
281   K         0.204   0.211   0.175  -0.172  -0.144  -0.214   0.068   0.080   0.019
282   S         1.861   1.865   1.891   1.952   1.962   1.996   1.999   2.003   2.037
283   T        -0.999  -0.997  -0.981  -0.634  -0.629  -0.600  -0.897  -0.893  -0.863
284   K         1.861   1.865   1.891   1.498   1.520   1.541   1.999   2.003   2.037
285   C        -0.999  -0.997  -0.981  -0.936  -0.937  -0.904  -0.897  -0.893  -0.863
286   N         0.204   0.211   0.175   0.276   0.287   0.230   0.068   0.080   0.019
287   P        -0.999  -0.997  -0.981  -0.710  -0.708  -0.676  -0.897  -0.893  -0.863
288   S        -0.999  -0.997  -0.981  -0.866  -0.867  -0.833  -0.897  -0.893  -0.863
289   S        -0.999  -0.997  -0.981  -0.812  -0.801  -0.779  -0.897  -0.893  -0.863
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   Q         0.057   0.058   0.079  -0.308  -0.305  -0.273  -0.173  -0.171  -0.138
296   Y         0.057   0.058   0.079   0.280   0.288   0.318  -0.173  -0.171  -0.138
297   Q         0.204   0.178   0.162   0.383   0.336   0.314   0.068   0.026  -0.001
298   K        -0.999  -0.997  -0.981  -1.135  -1.105  -1.103  -0.897  -0.893  -0.863
299   V        -0.999  -0.997  -0.981  -0.951  -0.940  -0.919  -0.897  -0.893  -0.863
300   K        -0.999  -0.997  -0.981  -1.143  -1.126  -1.111  -0.897  -0.893  -0.863
301   E        -0.999  -0.997  -0.981  -0.741  -0.739  -0.708  -0.897  -0.893  -0.863
302   W         1.861   1.865   1.891   2.232   2.236   2.278   1.999   2.003   2.037
303   V        -0.999  -0.997  -0.981  -1.099  -1.100  -1.068  -0.897  -0.893  -0.863
304   D        -0.999  -0.997  -0.981  -1.049  -1.052  -1.017  -0.897  -0.893  -0.863
305   P         1.861   1.865   1.891   2.099   2.101   2.145   1.999   2.003   2.037
306   V         0.204   0.231   0.182   0.262   0.301   0.231   0.068   0.112   0.032
307   R        -0.999  -0.997  -0.981  -1.131  -1.149  -1.099  -0.897  -0.893  -0.863
308   E         0.204   0.211   0.175   0.240   0.250   0.189   0.068   0.080   0.019
309   I        -0.999  -0.997  -0.981  -0.815  -0.808  -0.783  -0.897  -0.893  -0.863
310   M         0.204   0.211   0.175   0.481   0.490   0.420   0.068   0.080   0.019
311   F        -0.999  -0.997  -0.981  -0.917  -0.916  -0.885  -0.897  -0.893  -0.863
312   E        -0.999  -0.997  -0.981  -0.936  -0.937  -0.904  -0.897  -0.893  -0.863
313   L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
314   H        -0.999  -0.997  -0.981  -0.794  -0.798  -0.761  -0.897  -0.893  -0.863
315   S        -0.999  -0.997  -0.981  -0.951  -0.951  -0.919  -0.897  -0.893  -0.863
316   K        -0.999  -0.997  -0.981  -1.170  -1.150  -1.139  -0.897  -0.893  -0.863
317   S        -0.999  -0.997  -0.981  -1.158  -1.151  -1.127  -0.897  -0.893  -0.863
318   F        -0.999  -0.997  -0.981  -0.745  -0.744  -0.712  -0.897  -0.893  -0.863
319   Q         0.204   0.178   0.162   0.330   0.281   0.253   0.068   0.026  -0.001
320   R         0.204   0.178   0.162   0.259   0.209   0.200   0.068   0.026  -0.001
321   V         0.204   0.231   0.182   0.397   0.441   0.362   0.068   0.112   0.032
322   E        -0.999  -0.997  -0.981  -0.780  -0.788  -0.747  -0.897  -0.893  -0.863
323   Y         0.204   0.231   0.182  -0.133  -0.077  -0.160   0.068   0.112   0.032
324   F         0.204   0.211   0.175   0.439   0.450   0.386   0.068   0.080   0.019
325   N        -0.999  -0.997  -0.981  -0.759  -0.754  -0.726  -0.897  -0.893  -0.863
326   K         0.204   0.178   0.162  -0.169  -0.195  -0.228   0.068   0.026  -0.001
327   Y        -0.999  -0.997  -0.981  -1.107  -1.099  -1.076  -0.897  -0.893  -0.863
328   K         0.204   0.178   0.162  -0.196  -0.227  -0.260   0.068   0.026  -0.001
329   E        -0.999  -0.997  -0.981  -0.706  -0.705  -0.673  -0.897  -0.893  -0.863
330   K         0.204   0.178   0.162  -0.055  -0.074  -0.098   0.068   0.026  -0.001
331   L         0.204   0.211   0.175  -0.151  -0.147  -0.196   0.068   0.080   0.019
332   L         0.204   0.178   0.162  -0.151  -0.199  -0.214   0.068   0.026  -0.001
333   K        -0.999  -0.997  -0.981  -1.064  -1.039  -1.033  -0.897  -0.893  -0.863
334   N         0.057   0.058   0.079   0.120   0.126   0.157  -0.173  -0.171  -0.138
335   G         0.204   0.211   0.175   0.204   0.222   0.124   0.068   0.080   0.019
336   G         0.204   0.178   0.162   0.204   0.150   0.095   0.068   0.026  -0.001
337   Q         0.204   0.211   0.175   0.397   0.409   0.350   0.068   0.080   0.019
338   L         0.204   0.231   0.182   0.120   0.175   0.062   0.068   0.112   0.032
339   A        -0.999  -0.997  -0.981  -0.741  -0.748  -0.708  -0.897  -0.893  -0.863
340   Y         1.861   1.865   1.891   1.999   2.007   2.044   1.999   2.003   2.037
341   F         0.204   0.231   0.182   0.383   0.426   0.352   0.068   0.112   0.032
342   D        -0.999  -0.997  -0.981  -0.992  -1.000  -0.960  -0.897  -0.893  -0.863
343   K         0.204   0.178   0.162  -0.112  -0.134  -0.163   0.068   0.026  -0.001
344   K         0.204   0.178   0.162  -0.364  -0.401  -0.454   0.068   0.026  -0.001
345   S         0.204   0.178   0.162   0.248   0.209   0.174   0.068   0.026  -0.001
346   K         0.204   0.178   0.162  -0.112  -0.134  -0.163   0.068   0.026  -0.001
347   E         0.204   0.231   0.182   0.179   0.212   0.141   0.068   0.112   0.032
348   M        -0.999  -0.997  -0.981  -0.888  -0.901  -0.855  -0.897  -0.893  -0.863
349   Y         0.204   0.211   0.175   0.383   0.395   0.340   0.068   0.080   0.019
350   A        -0.999  -0.997  -0.981  -1.045  -1.052  -1.013  -0.897  -0.893  -0.863
351   K         0.204   0.211   0.175  -0.172  -0.144  -0.214   0.068   0.080   0.019
352   R         0.204   0.211   0.175   0.284   0.284   0.245   0.068   0.080   0.019
353   L         0.204   0.211   0.175   0.015   0.020  -0.011   0.068   0.080   0.019
354   T        -0.999  -0.997  -0.981  -1.080  -1.073  -1.048  -0.897  -0.893  -0.863
355   L        -0.999  -0.997  -0.981  -1.092  -1.092  -1.060  -0.897  -0.893  -0.863
356   F         0.204   0.211   0.175   0.439   0.450   0.386   0.068   0.080   0.019
357   R        -0.999  -0.997  -0.981  -1.499  -1.503  -1.469  -0.897  -0.893  -0.863
358   K        -0.999  -0.997  -0.981  -1.111  -1.089  -1.080  -0.897  -0.893  -0.863
359   M         0.204   0.178   0.162   0.330   0.268   0.221   0.068   0.026  -0.001
360   S         0.057   0.058   0.079   0.057   0.063   0.094  -0.173  -0.171  -0.138
361   K         1.861   1.865   1.891   1.498   1.520   1.541   1.999   2.003   2.037
362   E        -0.999  -0.997  -0.981  -0.862  -0.859  -0.830  -0.897  -0.893  -0.863
363   T         0.204   0.231   0.182   0.308   0.344   0.278   0.068   0.112   0.032
364   L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
365   P         1.861   1.865   1.891   2.099   2.101   2.145   1.999   2.003   2.037
366   Y        -0.999  -0.997  -0.981  -0.665  -0.661  -0.631  -0.897  -0.893  -0.863
367   V         0.204   0.178   0.162   0.436   0.400   0.371   0.068   0.026  -0.001
368   T         0.204   0.231   0.182   0.303   0.344   0.272   0.068   0.112   0.032
369   L         0.204   0.231   0.182   0.215   0.266   0.155   0.068   0.112   0.032
370   F         1.861   1.865   1.891   2.123   2.126   2.168   1.999   2.003   2.037
371   I         0.204   0.178   0.162   0.276   0.228   0.216   0.068   0.026  -0.001
372   E         1.861   1.865   1.891   1.928   1.928   1.972   1.999   2.003   2.037
373   G        -0.999  -0.997  -0.981  -0.851  -0.863  -0.819  -0.897  -0.893  -0.863
374   R        -0.999  -0.997  -0.981  -1.499  -1.504  -1.469  -0.897  -0.893  -0.863
375   D        -0.999  -0.997  -0.981  -0.798  -0.797  -0.765  -0.897  -0.893  -0.863
376   L         0.204   0.211   0.175  -0.151  -0.147  -0.196   0.068   0.080   0.019
377   P         0.204   0.231   0.182   0.468   0.507   0.434   0.068   0.112   0.032
378   S         0.204   0.178   0.162   0.303   0.264   0.237   0.068   0.026  -0.001
379   V        -0.999  -0.997  -0.981  -1.099  -1.113  -1.068  -0.897  -0.893  -0.863
380   L         1.861   1.865   1.891   1.537   1.538   1.580   1.999   2.003   2.037
381   A        -0.999  -0.997  -0.981  -1.026  -1.005  -0.994  -0.897  -0.893  -0.863
382   K         0.204   0.211   0.175  -0.196  -0.174  -0.241   0.068   0.080   0.019
383   Y        -0.999  -0.997  -0.981  -0.703  -0.691  -0.669  -0.897  -0.893  -0.863
384   G         0.204   0.178   0.162   0.367   0.311   0.285   0.068   0.026  -0.001
385   F         0.204   0.211   0.175   0.391   0.399   0.333   0.068   0.080   0.019
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   -         0.057   0.058   0.079  -0.313  -0.311  -0.278  -0.173  -0.171  -0.138
394   -         1.861   1.865   1.891   2.041   2.046   2.086   1.999   2.003   2.037
395   -         1.861   1.865   1.891   1.569   1.574   1.612   1.999   2.003   2.037
396   -         0.057   0.058   0.079   0.071   0.073   0.107  -0.173  -0.171  -0.138
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12167
Output conservation file - output/Q12167
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
