1     M         2.346   2.365   2.507   2.574   2.605   2.829   2.704   2.733   2.996
2     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    P        -1.010  -1.033  -0.977  -0.840  -0.876  -0.783  -0.885  -0.900  -0.816
43    P         1.458   1.449   1.344   1.648   1.637   1.498   1.571   1.551   1.333
44    N        -0.848  -0.820  -0.871  -0.507  -0.473  -0.525  -0.696  -0.663  -0.699
45    L        -1.439  -1.450  -1.394  -1.452  -1.443  -1.395  -1.074  -1.081  -0.996
46    P        -0.848  -0.919  -0.920  -0.488  -0.596  -0.600  -0.696  -0.772  -0.752
47    A        -0.419  -0.479  -0.435  -0.505  -0.597  -0.525  -0.507  -0.574  -0.507
48    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    D         0.095   0.094   0.159   0.174   0.165   0.246  -0.189  -0.193  -0.115
52    K         0.156   0.169   0.204   0.017   0.041   0.062  -0.124  -0.101  -0.059
53    S        -1.010  -0.988  -0.963  -0.848  -0.814  -0.774  -0.885  -0.862  -0.804
54    L        -0.848  -0.824  -0.876  -1.043  -1.001  -1.087  -0.696  -0.670  -0.705
55    V        -0.581  -0.576  -0.499  -0.718  -0.705  -0.597  -0.696  -0.687  -0.582
56    Q        -0.419  -0.413  -0.417  -0.206  -0.212  -0.177  -0.507  -0.507  -0.486
57    R         0.622   0.601   0.433   0.871   0.842   0.609   0.626   0.594   0.321
58    F        -0.419  -0.466  -0.439  -0.790  -0.874  -0.858  -0.507  -0.561  -0.512
59    M        -0.848  -0.828  -0.874  -0.834  -0.816  -0.829  -0.696  -0.673  -0.703
60    A        -0.581  -0.585  -0.499  -0.537  -0.532  -0.397  -0.696  -0.696  -0.582
61    V         0.172   0.160   0.209  -0.327  -0.341  -0.268  -0.130  -0.141  -0.065
62    A        -0.848  -0.919  -0.920  -0.813  -0.936  -0.957  -0.696  -0.772  -0.752
63    K         1.051   1.040   1.071   1.025   1.006   1.035   0.815   0.784   0.776
64    S         0.277   0.296   0.288   0.263   0.321   0.306   0.059   0.108   0.079
65    L         0.277   0.254   0.242  -0.067  -0.106  -0.098   0.059   0.014  -0.007
66    Q         1.458   1.449   1.344   1.683   1.676   1.546   1.571   1.551   1.333
67    F         2.346   2.365   2.507   2.189   2.220   2.431   2.704   2.733   2.996
68    A         0.622   0.572   0.431   0.668   0.591   0.380   0.626   0.548   0.318
69    W         2.346   2.365   2.507   2.581   2.610   2.835   2.704   2.733   2.996
70    F         2.346   2.365   2.507   2.189   2.220   2.431   2.704   2.733   2.996
71    T        -1.010  -1.011  -0.964  -1.102  -1.112  -1.033  -0.885  -0.883  -0.805
72    G         2.346   2.365   2.507   2.488   2.515   2.739   2.704   2.733   2.996
73    H         1.458   1.402   1.334   1.835   1.769   1.696   1.571   1.469   1.314
74    S        -1.010  -0.976  -0.962  -1.315  -1.256  -1.271  -0.885  -0.851  -0.804
75    V        -0.848  -0.864  -0.881  -1.082  -1.108  -1.143  -0.696  -0.714  -0.711
76    V         0.622   0.590   0.435   0.586   0.547   0.281   0.626   0.577   0.324
77    L         1.051   1.095   1.098   0.536   0.609   0.570   0.815   0.894   0.834
78    I        -0.581  -0.586  -0.498  -0.899  -0.900  -0.766  -0.696  -0.697  -0.582
79    S         0.010   0.004   0.097   0.017   0.017   0.170  -0.319  -0.329  -0.212
80    S        -0.152  -0.179  -0.300   0.006  -0.032  -0.196  -0.130  -0.164  -0.319
81    I        -1.010  -0.998  -0.964  -1.220  -1.193  -1.176  -0.885  -0.873  -0.805
82    L         0.277   0.270   0.251  -0.156  -0.167  -0.197   0.059   0.048   0.010
83    Y         1.458   1.435   1.341   1.632   1.604   1.469   1.571   1.527   1.327
84    L        -1.010  -1.020  -0.975  -1.188  -1.166  -1.087  -0.885  -0.888  -0.814
85    L         1.051   1.103   1.092   0.529   0.615   0.550   0.815   0.910   0.822
86    -        -0.539  -0.522  -0.475  -0.599  -0.571  -0.513  -0.628  -0.607  -0.544
87    -        -1.139  -1.131  -1.041  -1.285  -1.291  -1.147  -0.999  -0.988  -0.874
88    -         0.845   0.858   0.979   0.320   0.342   0.513   0.390   0.407   0.578
89    -         0.095   0.108   0.170   0.092   0.112   0.196  -0.189  -0.170  -0.099
90    -         0.095   0.108   0.170  -0.015   0.002   0.094  -0.189  -0.170  -0.099
91    -        -0.656  -0.648  -0.549  -0.602  -0.589  -0.443  -0.767  -0.757  -0.632
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -         0.095   0.084   0.157   0.008  -0.016   0.073  -0.189  -0.207  -0.119
95    K         0.010   0.016   0.107  -0.133  -0.137  -0.006  -0.319  -0.313  -0.196
96    M        -0.419  -0.456  -0.409  -0.504  -0.563  -0.504  -0.507  -0.543  -0.475
97    S        -1.439  -1.452  -1.391  -1.044  -1.069  -0.943  -1.074  -1.083  -0.993
98    E        -0.848  -0.911  -0.925  -0.356  -0.451  -0.475  -0.696  -0.763  -0.758
99    F         0.622   0.690   0.462   0.636   0.728   0.414   0.626   0.725   0.367
100   Y        -0.419  -0.373  -0.406  -0.266  -0.195  -0.234  -0.507  -0.454  -0.472
101   Y         1.458   1.402   1.334   1.632   1.558   1.459   1.571   1.469   1.314
102   R         0.622   0.536   0.416   0.893   0.775   0.618   0.626   0.494   0.294
103   S        -1.439  -1.426  -1.384  -1.218  -1.233  -1.128  -1.074  -1.060  -0.987
104   A         0.277   0.270   0.251   0.154   0.135   0.108   0.059   0.048   0.010
105   Y        -0.419  -0.438  -0.407  -0.586  -0.621  -0.601  -0.507  -0.515  -0.467
106   L         0.277   0.314   0.257  -0.210  -0.174  -0.265   0.059   0.087   0.018
107   G         1.051   1.060   1.084   1.064   1.074   1.070   0.815   0.825   0.804
108   V         0.172   0.164   0.214  -0.120  -0.123  -0.043  -0.130  -0.132  -0.057
109   I        -0.152  -0.103  -0.266  -0.040   0.040  -0.228  -0.130  -0.065  -0.275
110   E        -0.419  -0.440  -0.407  -0.381  -0.404  -0.404  -0.507  -0.522  -0.473
111   S         0.277   0.230   0.244   0.156   0.085   0.096   0.059  -0.005   0.002
112   F         1.051   1.023   1.062   0.852   0.809   0.850   0.815   0.750   0.758
113   G         1.458   1.402   1.334   1.691   1.615   1.525   1.571   1.469   1.314
114   I         1.458   1.449   1.344   1.493   1.480   1.335   1.571   1.551   1.333
115   I         0.010  -0.008   0.092  -0.463  -0.518  -0.396  -0.319  -0.347  -0.218
116   I        -0.581  -0.534  -0.499  -0.981  -0.943  -0.865  -0.696  -0.650  -0.582
117   Y         1.458   1.475   1.347   1.632   1.659   1.480   1.571   1.597   1.340
118   Q         0.277   0.258   0.241   0.425   0.389   0.381   0.059   0.022  -0.006
119   Q         0.277   0.322   0.303   0.236   0.309   0.254   0.059   0.145   0.101
120   F        -0.848  -0.774  -0.864  -0.481  -0.373  -0.500  -0.696  -0.613  -0.692
121   F        -1.868  -1.855  -1.782  -1.749  -1.697  -1.624  -1.263  -1.251  -1.150
122   T        -1.439  -1.400  -1.381  -1.027  -0.986  -0.927  -1.074  -1.038  -0.984
123   R        -1.010  -1.003  -0.965  -0.769  -0.767  -0.685  -0.885  -0.877  -0.806
124   N        -1.010  -0.987  -0.954  -1.005  -1.013  -0.916  -0.885  -0.860  -0.796
125   E        -0.419  -0.420  -0.407  -0.620  -0.628  -0.566  -0.507  -0.511  -0.475
126   P        -1.010  -0.979  -0.956  -0.848  -0.811  -0.747  -0.885  -0.855  -0.798
127   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   T         0.095   0.101   0.167   0.164   0.171   0.256  -0.189  -0.181  -0.104
136   K         0.095   0.123   0.169  -0.234  -0.196  -0.140  -0.189  -0.148  -0.101
137   A        -0.656  -0.647  -0.549  -0.791  -0.780  -0.638  -0.767  -0.756  -0.632
138   S         0.095   0.101   0.167   0.103   0.119   0.200  -0.189  -0.181  -0.104
139   I        -0.656  -0.647  -0.549  -0.845  -0.823  -0.693  -0.767  -0.756  -0.632
140   K         0.845   0.858   0.979   0.743   0.761   0.942   0.390   0.406   0.577
141   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   V         0.156   0.168   0.201  -0.066  -0.058  -0.004  -0.124  -0.115  -0.069
144   A        -1.033  -1.019  -0.976  -0.920  -0.900  -0.823  -0.896  -0.878  -0.811
145   G        -1.010  -1.000  -0.958  -0.835  -0.818  -0.743  -0.885  -0.873  -0.800
146   L        -0.152  -0.199  -0.302  -0.342  -0.409  -0.563  -0.130  -0.191  -0.322
147   L        -0.152  -0.215  -0.302  -0.292  -0.372  -0.491  -0.130  -0.212  -0.322
148   K        -0.581  -0.598  -0.500  -0.677  -0.717  -0.573  -0.696  -0.708  -0.583
149   S         0.622   0.774   0.479   1.036   1.236   0.848   0.626   0.855   0.393
150   E         0.867   0.866   0.981   0.943   0.937   1.112   0.437   0.423   0.582
151   D         1.458   1.541   1.363   1.768   1.868   1.683   1.571   1.707   1.371
152   V         1.458   1.435   1.341   1.426   1.404   1.279   1.571   1.527   1.327
153   L         0.172   0.188   0.210  -0.124  -0.070  -0.025  -0.130  -0.106  -0.062
154   Y         2.346   2.365   2.507   2.439   2.467   2.689   2.704   2.733   2.996
155   L         0.867   0.890   0.997   0.253   0.300   0.424   0.437   0.475   0.616
156   V        -0.152  -0.078  -0.271  -0.394  -0.289  -0.591  -0.130  -0.035  -0.281
157   L         1.458   1.475   1.347   1.152   1.177   0.994   1.571   1.597   1.340
158   A         0.622   0.578   0.429   0.716   0.653   0.452   0.626   0.558   0.313
159   N        -0.848  -0.837  -0.880  -1.045  -1.043  -1.094  -0.696  -0.682  -0.709
160   F        -0.848  -0.856  -0.876  -0.952  -0.961  -1.044  -0.696  -0.705  -0.705
161   W         0.622   0.536   0.416   1.004   0.889   0.694   0.626   0.494   0.294
162   L         1.458   1.560   1.365   1.149   1.282   1.016   1.571   1.738   1.374
163   F        -0.419  -0.450  -0.431  -0.687  -0.744  -0.742  -0.507  -0.547  -0.503
164   T        -1.439  -1.482  -1.417  -1.212  -1.275  -1.184  -1.074  -1.108  -1.015
165   -         0.095   0.109   0.169   0.017   0.034   0.109  -0.189  -0.170  -0.100
166   P         2.346   2.365   2.507   2.446   2.471   2.696   2.704   2.733   2.996
167   R         0.289   0.218   0.225   0.461   0.351   0.357   0.112  -0.001  -0.012
168   F        -1.010  -1.014  -0.969  -1.044  -1.037  -0.963  -0.885  -0.882  -0.808
169   S        -1.010  -1.008  -0.975  -1.190  -1.208  -1.127  -0.885  -0.877  -0.814
170   F        -0.419  -0.357  -0.399  -0.569  -0.469  -0.554  -0.507  -0.438  -0.464
171   S        -0.419  -0.440  -0.429  -0.476  -0.511  -0.479  -0.507  -0.531  -0.501
172   L        -0.152  -0.169  -0.293  -0.294  -0.313  -0.482  -0.130  -0.150  -0.311
173   I        -0.419  -0.390  -0.412  -0.807  -0.772  -0.800  -0.507  -0.472  -0.479
174   P         2.346   2.365   2.507   2.446   2.471   2.696   2.704   2.733   2.996
175   F         1.051   1.068   1.080   0.852   0.881   0.878   0.815   0.841   0.795
176   F         0.867   0.904   1.009   0.452   0.518   0.660   0.437   0.505   0.643
177   A        -0.152  -0.051  -0.253  -0.040   0.085  -0.206  -0.130   0.002  -0.257
178   F         0.277   0.239   0.239   0.153   0.098   0.102   0.059  -0.004  -0.009
179   A         1.051   1.059   1.077   0.836   0.845   0.834   0.815   0.823   0.790
180   V         0.172   0.142   0.207  -0.327  -0.365  -0.271  -0.130  -0.159  -0.066
181   F         2.346   2.365   2.507   2.189   2.220   2.431   2.704   2.733   2.996
182   H         2.346   2.365   2.507   2.600   2.629   2.855   2.704   2.733   2.996
183   V         0.622   0.548   0.423   0.633   0.534   0.336   0.626   0.512   0.304
184   L         0.622   0.560   0.425   0.372   0.284   0.073   0.626   0.531   0.307
185   I        -0.152  -0.051  -0.253   0.001   0.144  -0.170  -0.130   0.002  -0.257
186   Y         2.346   2.365   2.507   2.439   2.467   2.689   2.704   2.733   2.996
187   V        -0.581  -0.581  -0.500  -0.962  -0.955  -0.847  -0.696  -0.693  -0.583
188   E        -0.419  -0.373  -0.401  -0.284  -0.224  -0.246  -0.507  -0.450  -0.467
189   K        -1.010  -1.006  -0.968  -0.847  -0.848  -0.787  -0.885  -0.879  -0.808
190   V        -1.439  -1.426  -1.384  -1.168  -1.140  -1.068  -1.074  -1.060  -0.987
191   L         1.051   1.053   1.075   0.574   0.572   0.578   0.815   0.810   0.784
192   L         0.622   0.602   0.441   0.382   0.354   0.114   0.626   0.595   0.333
193   P         1.458   1.449   1.344   1.648   1.637   1.498   1.571   1.551   1.333
194   K        -1.033  -0.972  -0.973  -0.880  -0.810  -0.774  -0.896  -0.831  -0.808
195   V         0.172   0.188   0.210  -0.168  -0.136  -0.126  -0.130  -0.106  -0.062
196   F        -0.848  -0.903  -0.913  -0.731  -0.806  -0.815  -0.696  -0.755  -0.745
197   H        -1.439  -1.393  -1.383  -0.842  -0.792  -0.735  -1.074  -1.031  -0.986
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   L        -1.439  -1.422  -1.392  -1.198  -1.163  -1.142  -1.074  -1.058  -0.994
200   S        -1.010  -1.026  -0.960  -0.858  -0.881  -0.763  -0.885  -0.895  -0.802
201   S        -0.848  -0.747  -0.861  -0.429  -0.264  -0.461  -0.696  -0.582  -0.689
202   K        -1.010  -0.954  -0.956  -0.942  -0.887  -0.839  -0.885  -0.834  -0.797
203   D        -1.010  -0.943  -0.955  -0.769  -0.686  -0.681  -0.885  -0.823  -0.796
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   S        -0.539  -0.544  -0.488  -0.571  -0.589  -0.520  -0.628  -0.637  -0.560
219   S         0.889   0.887   0.990   0.684   0.683   0.846   0.482   0.468   0.601
220   K         0.062   0.040   0.139   0.037   0.009   0.159  -0.258  -0.283  -0.153
221   I        -1.010  -1.017  -0.960  -1.035  -1.037  -0.955  -0.885  -0.887  -0.801
222   L         0.277   0.372   0.275  -0.037   0.115  -0.083   0.059   0.193   0.048
223   S        -1.868  -1.855  -1.782  -1.441  -1.422  -1.307  -1.263  -1.251  -1.150
224   F        -0.419  -0.466  -0.439  -0.573  -0.649  -0.625  -0.507  -0.561  -0.512
225   I         1.458   1.402   1.334   1.453   1.368   1.249   1.571   1.469   1.314
226   D        -0.152  -0.234  -0.317   0.400   0.291   0.196  -0.130  -0.237  -0.341
227   K        -1.010  -1.038  -0.981  -0.756  -0.784  -0.699  -0.885  -0.905  -0.820
228   F         0.622   0.548   0.423   0.587   0.490   0.273   0.626   0.512   0.304
229   V         0.622   0.536   0.416   0.653   0.541   0.359   0.626   0.494   0.294
230   V        -1.010  -0.966  -0.960  -1.100  -1.015  -1.045  -0.885  -0.845  -0.801
231   Q        -1.010  -1.042  -0.967  -0.687  -0.740  -0.624  -0.885  -0.910  -0.808
232   Y         0.277   0.211   0.232   0.448   0.356   0.397   0.059  -0.038  -0.021
233   N        -0.152  -0.224  -0.310   0.271   0.163   0.048  -0.130  -0.224  -0.332
234   D        -0.419  -0.463  -0.420  -0.042  -0.097  -0.026  -0.507  -0.550  -0.487
235   L        -1.439  -1.411  -1.390  -1.298  -1.242  -1.240  -1.074  -1.048  -0.992
236   C        -0.419  -0.413  -0.399  -0.341  -0.346  -0.326  -0.507  -0.486  -0.456
237   M         0.622   0.578   0.429   0.945   0.883   0.622   0.626   0.558   0.313
238   H        -1.439  -1.381  -1.383  -1.006  -0.928  -0.915  -1.074  -1.020  -0.986
239   W        -1.010  -1.033  -0.977  -0.978  -1.053  -0.978  -0.885  -0.900  -0.816
240   V         0.277   0.255   0.245   0.079   0.043   0.015   0.059   0.024   0.002
241   G        -0.419  -0.373  -0.401  -0.374  -0.312  -0.312  -0.507  -0.450  -0.467
242   T        -0.419  -0.438  -0.407  -0.358  -0.381  -0.364  -0.507  -0.515  -0.467
243   A        -0.848  -0.765  -0.870  -1.066  -0.952  -1.107  -0.696  -0.603  -0.698
244   E         2.346   2.365   2.507   2.565   2.595   2.819   2.704   2.733   2.996
245   L        -0.152  -0.225  -0.317  -0.371  -0.476  -0.629  -0.130  -0.225  -0.341
246   L        -0.848  -0.911  -0.925  -0.970  -1.056  -1.056  -0.696  -0.763  -0.758
247   I        -1.010  -0.997  -0.958  -0.923  -0.930  -0.832  -0.885  -0.870  -0.799
248   F         0.172   0.175   0.216  -0.276  -0.268  -0.184  -0.130  -0.123  -0.057
249   I         0.010   0.035   0.109  -0.567  -0.535  -0.433  -0.319  -0.283  -0.194
250   L        -1.010  -1.020  -0.975  -0.934  -0.902  -0.806  -0.885  -0.888  -0.814
251   V        -0.152  -0.118  -0.260  -0.321  -0.269  -0.472  -0.130  -0.085  -0.266
252   L        -0.419  -0.420  -0.404  -0.744  -0.729  -0.729  -0.507  -0.502  -0.469
253   F        -0.581  -0.577  -0.498  -0.960  -0.952  -0.861  -0.696  -0.689  -0.582
254   R         0.468   0.444   0.340   0.648   0.613   0.439   0.390   0.352   0.171
255   A        -0.152  -0.244  -0.321  -0.120  -0.264  -0.416  -0.130  -0.250  -0.346
256   I         0.277   0.271   0.255   0.066   0.055  -0.022   0.059   0.054   0.016
257   L        -0.419  -0.464  -0.430  -0.763  -0.826  -0.770  -0.507  -0.557  -0.501
258   C         0.622   0.630   0.450   0.635   0.630   0.392   0.626   0.633   0.347
259   F         0.010   0.060   0.136  -0.113  -0.019   0.083  -0.319  -0.246  -0.153
260   Q        -0.581  -0.542  -0.501  -0.588  -0.541  -0.456  -0.696  -0.658  -0.584
261   R         0.622   0.572   0.431   0.927   0.860   0.695   0.626   0.548   0.318
262   S         2.346   2.365   2.507   2.250   2.277   2.494   2.704   2.733   2.996
263   W        -0.152  -0.244  -0.321   0.156   0.003  -0.175  -0.130  -0.250  -0.346
264   I         1.458   1.402   1.334   1.500   1.423   1.332   1.571   1.469   1.314
265   I        -1.868  -1.855  -1.782  -1.792  -1.762  -1.668  -1.263  -1.251  -1.150
266   L         0.622   0.578   0.429   0.432   0.378   0.176   0.626   0.558   0.313
267   V         0.622   0.601   0.433   0.633   0.608   0.353   0.626   0.594   0.321
268   V        -1.010  -1.048  -0.982  -1.056  -1.097  -1.005  -0.885  -0.915  -0.821
269   Y         0.277   0.303   0.270   0.247   0.308   0.207   0.059   0.109   0.040
270   A        -0.581  -0.598  -0.500  -0.786  -0.815  -0.668  -0.696  -0.708  -0.583
271   I        -0.419  -0.398  -0.413  -0.779  -0.734  -0.792  -0.507  -0.479  -0.479
272   F         2.346   2.365   2.507   2.189   2.220   2.431   2.704   2.733   2.996
273   I         0.277   0.333   0.297  -0.155  -0.061  -0.131   0.059   0.160   0.093
274   K         0.867   0.901   1.006   0.696   0.752   0.903   0.437   0.498   0.636
275   L        -1.010  -0.978  -0.960  -1.089  -0.999  -1.015  -0.885  -0.853  -0.802
276   R         1.051   1.095   1.098   1.035   1.102   1.082   0.815   0.894   0.834
277   Y         0.622   0.602   0.441   0.925   0.904   0.690   0.626   0.595   0.333
278   E        -0.419  -0.469  -0.432  -0.216  -0.295  -0.238  -0.507  -0.562  -0.503
279   N        -0.419  -0.382  -0.401  -0.166  -0.119  -0.129  -0.507  -0.467  -0.465
280   S         2.346   2.365   2.507   2.250   2.277   2.494   2.704   2.733   2.996
281   K        -1.439  -1.482  -1.417  -1.321  -1.386  -1.317  -1.074  -1.108  -1.015
282   Y         0.010   0.053   0.130  -0.084  -0.022   0.101  -0.319  -0.257  -0.163
283   M         0.172   0.180   0.210   0.201   0.206   0.255  -0.130  -0.115  -0.062
284   K         0.010   0.048   0.113  -0.026   0.032   0.123  -0.319  -0.262  -0.187
285   A        -0.419  -0.435  -0.430  -0.364  -0.389  -0.359  -0.507  -0.526  -0.501
286   A        -0.419  -0.392  -0.394  -0.520  -0.459  -0.466  -0.507  -0.460  -0.450
287   F         0.277   0.254   0.242   0.064   0.020  -0.012   0.059   0.014  -0.007
288   A        -0.419  -0.436  -0.437  -0.428  -0.461  -0.437  -0.507  -0.533  -0.509
289   Q        -1.010  -1.038  -0.981  -0.898  -0.952  -0.862  -0.885  -0.905  -0.820
290   W        -0.152  -0.234  -0.317   0.135  -0.002  -0.199  -0.130  -0.237  -0.341
291   R         0.277   0.296   0.288   0.470   0.518   0.491   0.059   0.108   0.079
292   V         0.277   0.240   0.235  -0.069  -0.155  -0.198   0.059  -0.006  -0.016
293   R         1.458   1.435   1.341   1.651   1.621   1.520   1.571   1.527   1.327
294   M        -0.419  -0.429  -0.428  -0.438  -0.476  -0.511  -0.507  -0.521  -0.500
295   D         2.346   2.365   2.507   2.571   2.599   2.825   2.704   2.733   2.996
296   G        -0.152  -0.234  -0.317   0.306   0.194   0.100  -0.130  -0.237  -0.341
297   I        -0.419  -0.377  -0.402  -0.837  -0.778  -0.813  -0.507  -0.454  -0.466
298   I         0.277   0.250   0.235   0.066   0.002  -0.065   0.059   0.006  -0.016
299   S        -0.419  -0.457  -0.431  -0.417  -0.477  -0.407  -0.507  -0.554  -0.504
300   H        -0.152  -0.234  -0.317   0.341   0.227   0.097  -0.130  -0.237  -0.341
301   P        -0.152  -0.234  -0.317   0.216   0.100  -0.010  -0.130  -0.237  -0.341
302   S        -1.010  -1.043  -0.978  -0.888  -0.922  -0.799  -0.885  -0.910  -0.817
303   I         0.468   0.527   0.380   0.426   0.513   0.292   0.390   0.479   0.236
304   P         1.458   1.435   1.341   1.692   1.665   1.567   1.571   1.527   1.327
305   P         1.458   1.449   1.344   1.706   1.698   1.597   1.571   1.551   1.333
306   F        -1.010  -1.010  -0.959  -0.939  -0.947  -0.867  -0.885  -0.882  -0.801
307   V         0.277   0.282   0.259   0.090   0.100   0.049   0.059   0.068   0.022
308   K         1.458   1.463   1.347   1.594   1.603   1.467   1.571   1.575   1.340
309   R        -1.439  -1.422  -1.392  -0.969  -0.934  -0.889  -1.074  -1.058  -0.994
310   A        -0.848  -0.824  -0.876  -0.831  -0.784  -0.903  -0.696  -0.670  -0.705
311   Y         0.867   0.904   1.009   0.878   0.947   1.098   0.437   0.505   0.643
312   N        -1.439  -1.482  -1.417  -0.959  -1.021  -0.925  -1.074  -1.108  -1.015
313   A        -0.848  -0.783  -0.872  -0.550  -0.461  -0.576  -0.696  -0.623  -0.701
314   I        -1.010  -0.966  -0.960  -1.272  -1.198  -1.224  -0.885  -0.845  -0.801
315   K         2.346   2.365   2.507   2.364   2.392   2.611   2.704   2.733   2.996
316   M        -1.439  -1.406  -1.385  -1.097  -1.054  -1.022  -1.074  -1.043  -0.988
317   S        -1.010  -1.015  -0.959  -1.120  -1.137  -1.045  -0.885  -0.887  -0.800
318   L        -0.152  -0.234  -0.317  -0.394  -0.520  -0.664  -0.130  -0.237  -0.341
319   I        -0.152  -0.078  -0.271   0.062   0.164  -0.141  -0.130  -0.035  -0.281
320   R        -0.581  -0.585  -0.499  -0.448  -0.453  -0.312  -0.696  -0.696  -0.582
321   L        -0.581  -0.564  -0.499  -1.026  -0.978  -0.880  -0.696  -0.675  -0.581
322   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -         0.289   0.331   0.283   0.401   0.474   0.368   0.112   0.177   0.081
346   -         0.062   0.080   0.146   0.017   0.042   0.146  -0.258  -0.235  -0.146
347   -        -0.539  -0.523  -0.474  -0.604  -0.584  -0.510  -0.628  -0.608  -0.542
348   -        -0.539  -0.535  -0.481  -0.527  -0.518  -0.446  -0.628  -0.623  -0.551
349   -        -0.539  -0.512  -0.477  -0.600  -0.568  -0.515  -0.628  -0.595  -0.546
350   -        -1.033  -1.027  -0.976  -1.115  -1.102  -1.039  -0.896  -0.887  -0.811
351   -        -0.533  -0.515  -0.467  -0.398  -0.374  -0.302  -0.639  -0.618  -0.544
352   -        -0.344  -0.313  -0.367  -0.212  -0.163  -0.245  -0.381  -0.340  -0.406
353   -        -1.033  -1.027  -0.976  -0.888  -0.883  -0.815  -0.896  -0.887  -0.811
354   -        -0.344  -0.349  -0.374  -0.253  -0.267  -0.307  -0.381  -0.387  -0.416
355   -         0.156   0.169   0.201   0.133   0.148   0.215  -0.124  -0.106  -0.066
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   K        -0.848  -0.852  -0.884  -0.499  -0.497  -0.534  -0.696  -0.702  -0.714
368   K         0.622   0.572   0.431   0.813   0.742   0.542   0.626   0.548   0.318
369   Q        -1.868  -1.855  -1.782  -1.585  -1.609  -1.456  -1.263  -1.251  -1.150
370   N        -1.010  -0.968  -0.959  -0.693  -0.658  -0.601  -0.885  -0.845  -0.801
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12164
Output conservation file - output/Q12164
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
