1     M         1.995   2.000   2.055   2.249   2.256   2.344   2.217   2.224   2.308
2     T        -0.204  -0.180  -0.174  -0.206  -0.179  -0.155  -0.396  -0.368  -0.347
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    V        -0.295  -0.291  -0.240  -0.249  -0.240  -0.165  -0.504  -0.498  -0.427
59    P         1.995   2.000   2.055   2.231   2.242   2.326   2.217   2.224   2.308
60    R        -0.782  -0.799  -0.790  -0.415  -0.440  -0.420  -0.722  -0.740  -0.715
61    N        -0.204  -0.203  -0.181  -0.163  -0.162  -0.121  -0.396  -0.393  -0.355
62    R         0.014   0.001  -0.085   0.207   0.185   0.030  -0.069  -0.087  -0.211
63    P        -0.782  -0.793  -0.786  -0.485  -0.502  -0.507  -0.722  -0.733  -0.711
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    M        -0.782  -0.769  -0.781  -0.558  -0.543  -0.544  -0.722  -0.706  -0.705
68    A         0.014   0.001  -0.085   0.274   0.253   0.123  -0.069  -0.087  -0.211
69    P         0.014   0.001  -0.085   0.313   0.294   0.140  -0.069  -0.087  -0.211
70    F         0.014  -0.011  -0.061  -0.126  -0.163  -0.265  -0.069  -0.104  -0.177
71    G        -0.204  -0.210  -0.177  -0.474  -0.496  -0.440  -0.396  -0.401  -0.350
72    T        -0.204  -0.210  -0.195  -0.144  -0.155  -0.122  -0.396  -0.402  -0.372
73    I        -0.782  -0.769  -0.781  -0.694  -0.671  -0.695  -0.722  -0.706  -0.705
74    I        -0.204  -0.210  -0.177  -0.720  -0.735  -0.686  -0.396  -0.401  -0.350
75    K        -1.360  -1.358  -1.307  -1.058  -1.058  -0.978  -1.049  -1.046  -0.974
76    S         0.592   0.607   0.640   0.496   0.524   0.562   0.257   0.284   0.320
77    R        -0.204  -0.210  -0.195  -0.465  -0.481  -0.431  -0.396  -0.402  -0.372
78    I        -0.204  -0.210  -0.195  -0.399  -0.412  -0.422  -0.396  -0.402  -0.372
79    K         0.014   0.011  -0.052   0.103   0.099  -0.033  -0.069  -0.073  -0.163
80    Q         0.014   0.001  -0.085   0.138   0.118  -0.025  -0.069  -0.087  -0.211
81    P         0.014   0.001  -0.085   0.339   0.320   0.172  -0.069  -0.087  -0.211
82    Q         1.995   2.000   2.055   2.058   2.064   2.151   2.217   2.224   2.308
83    F         1.995   2.000   2.055   1.872   1.882   1.964   2.217   2.224   2.308
84    Y         0.952   0.951   0.849   1.077   1.077   0.901   0.910   0.909   0.713
85    W         1.995   2.000   2.055   2.339   2.346   2.433   2.217   2.224   2.308
86    F         1.995   2.000   2.055   1.872   1.882   1.964   2.217   2.224   2.308
87    I         0.014   0.049  -0.045  -0.370  -0.319  -0.460  -0.069  -0.020  -0.154
88    G         1.995   2.000   2.055   2.229   2.236   2.323   2.217   2.224   2.308
89    H         1.995   2.000   2.055   2.310   2.317   2.405   2.217   2.224   2.308
90    F        -0.204  -0.210  -0.195  -0.364  -0.366  -0.337  -0.396  -0.402  -0.372
91    L         0.014  -0.001  -0.060  -0.319  -0.339  -0.418  -0.069  -0.089  -0.175
92    T        -1.360  -1.358  -1.307  -0.853  -0.848  -0.772  -1.049  -1.046  -0.974
93    I        -0.204  -0.210  -0.183  -0.661  -0.676  -0.618  -0.396  -0.401  -0.357
94    F        -0.782  -0.769  -0.781  -0.925  -0.899  -0.970  -0.722  -0.706  -0.705
95    N        -0.782  -0.770  -0.794  -0.655  -0.635  -0.643  -0.722  -0.707  -0.719
96    F         0.014  -0.001  -0.073   0.038   0.022  -0.076  -0.069  -0.090  -0.194
97    I         0.952   0.951   0.849   0.867   0.865   0.664   0.910   0.909   0.713
98    Q        -0.204  -0.204  -0.193  -0.544  -0.550  -0.504  -0.396  -0.394  -0.370
99    F        -1.360  -1.358  -1.307  -1.298  -1.287  -1.219  -1.049  -1.046  -0.974
100   H        -0.204  -0.210  -0.182   0.099   0.090   0.133  -0.396  -0.401  -0.356
101   L         0.952   0.953   0.855   0.578   0.580   0.436   0.910   0.912   0.724
102   S         0.014  -0.001  -0.060   0.114   0.092   0.011  -0.069  -0.089  -0.175
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   I        -0.172  -0.174  -0.187  -0.578  -0.602  -0.644  -0.334  -0.336  -0.355
105   T         0.014   0.037  -0.046   0.085   0.121   0.017  -0.069  -0.037  -0.156
106   S        -0.782  -0.800  -0.772  -0.595  -0.618  -0.568  -0.722  -0.741  -0.696
107   K        -0.782  -0.770  -0.794  -0.465  -0.445  -0.482  -0.722  -0.707  -0.719
108   Q        -0.172  -0.198  -0.179  -0.034  -0.063  -0.037  -0.334  -0.372  -0.344
109   N         0.550   0.560   0.611   0.343   0.344   0.430   0.176   0.195   0.264
110   Q        -0.782  -0.770  -0.794  -0.715  -0.699  -0.729  -0.722  -0.707  -0.719
111   L        -0.782  -0.793  -0.767  -0.988  -0.999  -0.944  -0.722  -0.733  -0.690
112   S        -0.782  -0.770  -0.794  -0.573  -0.550  -0.600  -0.722  -0.707  -0.719
113   C        -0.782  -0.770  -0.794  -0.378  -0.364  -0.374  -0.722  -0.707  -0.719
114   Y         1.995   2.000   2.055   2.112   2.120   2.206   2.217   2.224   2.308
115   R         0.952   0.953   0.855   1.181   1.183   1.039   0.910   0.912   0.724
116   R        -0.782  -0.776  -0.762  -0.428  -0.420  -0.411  -0.722  -0.715  -0.685
117   S        -0.782  -0.793  -0.767  -0.612  -0.629  -0.581  -0.722  -0.733  -0.690
118   L         0.952   0.938   0.847   0.644   0.626   0.516   0.910   0.886   0.709
119   F        -0.782  -0.762  -0.760  -1.137  -1.106  -1.096  -0.722  -0.698  -0.682
120   Y         0.014   0.001  -0.085   0.190   0.168   0.023  -0.069  -0.087  -0.211
121   I        -0.782  -0.793  -0.767  -0.911  -0.929  -0.906  -0.722  -0.733  -0.690
122   S        -1.360  -1.358  -1.307  -1.498  -1.496  -1.421  -1.049  -1.046  -0.974
123   V        -0.782  -0.799  -0.790  -1.016  -1.053  -1.079  -0.722  -0.740  -0.715
124   T         0.952   0.938   0.847   1.129   1.106   0.959   0.910   0.886   0.709
125   Y         1.995   2.000   2.055   2.112   2.120   2.206   2.217   2.224   2.308
126   A         0.014   0.037  -0.046   0.186   0.216   0.056  -0.069  -0.037  -0.156
127   I         1.995   2.000   2.055   1.972   1.979   2.065   2.217   2.224   2.308
128   V         1.995   2.000   2.055   2.015   2.021   2.108   2.217   2.224   2.308
129   L         0.592   0.589   0.633   0.004   0.000   0.067   0.257   0.251   0.307
130   Y        -0.782  -0.799  -0.790  -0.441  -0.461  -0.441  -0.722  -0.740  -0.715
131   Q         1.995   2.000   2.055   2.058   2.064   2.151   2.217   2.224   2.308
132   F        -0.204  -0.210  -0.195  -0.407  -0.409  -0.381  -0.396  -0.402  -0.372
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   F         0.592   0.589   0.629   0.290   0.286   0.341   0.257   0.250   0.299
135   K         1.995   2.000   2.055   2.138   2.145   2.231   2.217   2.224   2.308
136   S         0.952   0.953   0.855   0.994   0.994   0.855   0.910   0.912   0.724
137   D        -1.360  -1.358  -1.307  -0.922  -0.925  -0.842  -1.049  -1.046  -0.974
138   Q         0.823   0.756   0.753   0.927   0.827   0.821   0.686   0.565   0.537
139   L         0.823   0.756   0.753   0.378   0.273   0.260   0.686   0.565   0.537
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   K        -0.895  -0.887  -0.841  -0.628  -0.626  -0.547  -0.845  -0.835  -0.769
146   F         0.952   0.953   0.855   0.906   0.911   0.772   0.910   0.912   0.724
147   N        -0.782  -0.769  -0.781  -0.561  -0.541  -0.554  -0.722  -0.706  -0.705
148   F        -0.782  -0.799  -0.790  -0.773  -0.793  -0.772  -0.722  -0.740  -0.715
149   T        -0.782  -0.762  -0.760  -0.620  -0.596  -0.581  -0.722  -0.698  -0.682
150   L        -1.360  -1.358  -1.307  -1.252  -1.232  -1.173  -1.049  -1.046  -0.974
151   L         0.592   0.589   0.625   0.004  -0.000   0.057   0.257   0.250   0.291
152   R         0.014  -0.011  -0.061   0.277   0.240   0.159  -0.069  -0.104  -0.177
153   Q        -0.782  -0.793  -0.786  -0.617  -0.635  -0.624  -0.722  -0.733  -0.711
154   E         0.014   0.036  -0.060   0.308   0.337   0.200  -0.069  -0.037  -0.175
155   M         0.014   0.036  -0.060  -0.284  -0.258  -0.375  -0.069  -0.037  -0.175
156   K        -0.782  -0.769  -0.764  -1.000  -0.986  -0.954  -0.722  -0.706  -0.687
157   K        -0.782  -0.770  -0.794  -0.449  -0.431  -0.463  -0.722  -0.707  -0.719
158   L         0.592   0.589   0.633   0.224   0.224   0.300   0.257   0.251   0.307
159   D         0.952   0.938   0.854   1.376   1.358   1.245   0.910   0.887   0.722
160   N         0.952   0.951   0.849   1.146   1.146   0.997   0.910   0.909   0.713
161   L         0.592   0.589   0.633   0.032   0.028   0.096   0.257   0.251   0.307
162   Q         1.995   2.000   2.055   2.058   2.064   2.151   2.217   2.224   2.308
163   Y         1.995   2.000   2.055   2.112   2.120   2.206   2.217   2.224   2.308
164   F         0.952   0.938   0.854   0.765   0.745   0.572   0.910   0.887   0.722
165   A        -0.782  -0.770  -0.794  -1.006  -0.995  -0.981  -0.722  -0.707  -0.719
166   M         0.952   0.998   0.860   0.644   0.703   0.534   0.910   0.988   0.733
167   L        -0.204  -0.210  -0.195  -0.544  -0.544  -0.532  -0.396  -0.402  -0.372
168   F        -1.360  -1.358  -1.307  -1.556  -1.546  -1.479  -1.049  -1.046  -0.974
169   I        -0.204  -0.204  -0.175  -0.357  -0.357  -0.314  -0.396  -0.394  -0.349
170   L         0.592   0.589   0.633  -0.060  -0.063  -0.002   0.257   0.251   0.307
171   F        -0.204  -0.180  -0.174  -0.604  -0.566  -0.563  -0.396  -0.368  -0.347
172   L        -0.204  -0.210  -0.183  -0.661  -0.660  -0.629  -0.396  -0.401  -0.357
173   L        -0.204  -0.210  -0.195  -0.530  -0.527  -0.480  -0.396  -0.402  -0.372
174   S         1.995   2.000   2.055   1.968   1.972   2.061   2.217   2.224   2.308
175   Q        -1.360  -1.358  -1.307  -1.393  -1.398  -1.315  -1.049  -1.046  -0.974
176   -        -0.295  -0.288  -0.240  -0.458  -0.462  -0.376  -0.504  -0.494  -0.427
177   F        -0.204  -0.180  -0.191  -0.234  -0.194  -0.221  -0.396  -0.368  -0.367
178   N         0.952   0.998   0.860   1.249   1.316   1.114   0.910   0.988   0.733
179   I        -0.295  -0.293  -0.240  -0.517  -0.510  -0.435  -0.504  -0.501  -0.427
180   I        -0.782  -0.799  -0.790  -0.622  -0.644  -0.621  -0.722  -0.740  -0.715
181   I        -1.360  -1.358  -1.307  -1.296  -1.295  -1.217  -1.049  -1.046  -0.974
182   S        -1.360  -1.358  -1.307  -1.277  -1.270  -1.199  -1.049  -1.046  -0.974
183   G        -0.782  -0.800  -0.772  -0.531  -0.563  -0.530  -0.722  -0.741  -0.696
184   S        -0.782  -0.793  -0.767  -0.660  -0.676  -0.633  -0.722  -0.733  -0.690
185   L         0.952   0.938   0.847   0.658   0.640   0.535   0.910   0.886   0.709
186   Y         0.014  -0.001  -0.073   0.182   0.158   0.033  -0.069  -0.090  -0.194
187   S         1.995   2.000   2.055   1.968   1.972   2.061   2.217   2.224   2.308
188   P        -0.782  -0.770  -0.794  -0.845  -0.828  -0.858  -0.722  -0.707  -0.719
189   V        -0.782  -0.793  -0.786  -0.521  -0.535  -0.510  -0.722  -0.733  -0.711
190   I         1.995   2.000   2.055   1.972   1.979   2.065   2.217   2.224   2.308
191   F         0.592   0.589   0.629   0.348   0.346   0.404   0.257   0.250   0.299
192   S         0.952   0.938   0.854   1.000   0.979   0.863   0.910   0.887   0.722
193   I        -0.782  -0.800  -0.772  -1.037  -1.073  -1.053  -0.722  -0.741  -0.696
194   F         1.995   2.000   2.055   1.872   1.882   1.964   2.217   2.224   2.308
195   H         1.995   2.000   2.055   2.310   2.317   2.405   2.217   2.224   2.308
196   F        -0.782  -0.770  -0.794  -0.614  -0.588  -0.623  -0.722  -0.707  -0.719
197   L         0.952   0.938   0.854   0.565   0.545   0.416   0.910   0.887   0.722
198   N         0.592   0.589   0.633   0.573   0.567   0.630   0.257   0.251   0.307
199   Y         1.995   2.000   2.055   2.112   2.120   2.206   2.217   2.224   2.308
200   F         1.995   2.000   2.055   1.872   1.882   1.964   2.217   2.224   2.308
201   K         0.592   0.589   0.633   0.543   0.536   0.597   0.257   0.251   0.307
202   E         0.014   0.001  -0.085   0.406   0.386   0.242  -0.069  -0.087  -0.211
203   N         0.952   0.938   0.854   1.188   1.171   1.063   0.910   0.887   0.722
204   L         0.952   0.938   0.847   0.578   0.558   0.423   0.910   0.886   0.709
205   L         1.995   2.000   2.055   1.578   1.584   1.669   2.217   2.224   2.308
206   P         0.014   0.001  -0.085   0.340   0.320   0.174  -0.069  -0.087  -0.211
207   F         0.014   0.001  -0.085  -0.081  -0.098  -0.246  -0.069  -0.087  -0.211
208   L        -0.782  -0.769  -0.781  -0.925  -0.888  -0.947  -0.722  -0.706  -0.705
209   P         0.014  -0.001  -0.060   0.262   0.239   0.121  -0.069  -0.089  -0.175
210   L         0.014  -0.011  -0.061  -0.192  -0.221  -0.264  -0.069  -0.104  -0.177
211   I        -0.204  -0.210  -0.182  -0.159  -0.160  -0.102  -0.396  -0.401  -0.356
212   P         0.014   0.001  -0.085   0.313   0.294   0.140  -0.069  -0.087  -0.211
213   L        -0.782  -0.800  -0.772  -0.954  -0.969  -0.911  -0.722  -0.741  -0.696
214   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   L        -0.204  -0.203  -0.181  -0.509  -0.499  -0.449  -0.396  -0.393  -0.355
216   K        -0.204  -0.204  -0.193  -0.141  -0.142  -0.115  -0.396  -0.394  -0.370
217   N        -1.360  -1.358  -1.307  -1.056  -1.054  -0.976  -1.049  -1.046  -0.974
218   L        -1.360  -1.358  -1.307  -1.331  -1.310  -1.252  -1.049  -1.046  -0.974
219   L         0.014   0.001  -0.085  -0.250  -0.268  -0.364  -0.069  -0.087  -0.211
220   N         0.592   0.585   0.622   0.475   0.458   0.501   0.257   0.243   0.286
221   S        -0.782  -0.793  -0.767  -0.672  -0.689  -0.646  -0.722  -0.733  -0.690
222   K         0.014  -0.001  -0.060   0.247   0.226   0.130  -0.069  -0.089  -0.175
223   I         1.995   2.000   2.055   1.972   1.979   2.065   2.217   2.224   2.308
224   T        -0.204  -0.203  -0.180  -0.215  -0.217  -0.178  -0.396  -0.393  -0.353
225   V        -1.360  -1.358  -1.307  -1.095  -1.087  -1.016  -1.049  -1.046  -0.974
226   F         1.995   2.000   2.055   1.872   1.882   1.964   2.217   2.224   2.308
227   I         0.592   0.589   0.633   0.450   0.446   0.511   0.257   0.251   0.307
228   Q        -0.782  -0.770  -0.794  -0.596  -0.579  -0.595  -0.722  -0.707  -0.719
229   N        -0.782  -0.793  -0.786  -0.580  -0.596  -0.592  -0.722  -0.733  -0.711
230   Y        -0.204  -0.203  -0.175  -0.357  -0.358  -0.317  -0.396  -0.393  -0.348
231   N         1.995   2.000   2.055   2.117   2.124   2.210   2.217   2.224   2.308
232   G        -0.204  -0.204  -0.193  -0.078  -0.079  -0.052  -0.396  -0.394  -0.370
233   F        -1.360  -1.358  -1.307  -1.468  -1.455  -1.390  -1.049  -1.046  -0.974
234   F        -0.204  -0.204  -0.193  -0.199  -0.193  -0.159  -0.396  -0.394  -0.370
235   L         0.952   0.938   0.847   0.539   0.519   0.367   0.910   0.886   0.709
236   Q        -1.360  -1.358  -1.307  -1.266  -1.260  -1.187  -1.049  -1.046  -0.974
237   M        -0.204  -0.203  -0.175  -0.070  -0.072  -0.030  -0.396  -0.393  -0.348
238   A         1.995   2.000   2.055   2.142   2.146   2.236   2.217   2.224   2.308
239   Q        -1.360  -1.358  -1.307  -1.064  -1.065  -0.984  -1.049  -1.046  -0.974
240   V        -0.782  -0.770  -0.794  -0.448  -0.424  -0.454  -0.722  -0.707  -0.719
241   F        -0.204  -0.210  -0.195  -0.335  -0.339  -0.325  -0.396  -0.402  -0.372
242   E         1.995   2.000   2.055   2.298   2.305   2.393   2.217   2.224   2.308
243   I        -0.782  -0.793  -0.767  -0.925  -0.946  -0.920  -0.722  -0.733  -0.690
244   I        -0.782  -0.762  -0.760  -0.972  -0.937  -0.961  -0.722  -0.698  -0.682
245   C        -0.204  -0.210  -0.195  -0.321  -0.341  -0.290  -0.396  -0.402  -0.372
246   G        -0.782  -0.770  -0.794  -0.913  -0.902  -0.877  -0.722  -0.707  -0.719
247   L        -0.295  -0.291  -0.240  -0.456  -0.443  -0.374  -0.504  -0.498  -0.427
248   R        -0.295  -0.291  -0.240  -0.280  -0.279  -0.197  -0.504  -0.498  -0.427
249   V         0.550   0.553   0.607   0.250   0.262   0.337   0.176   0.180   0.257
250   G         0.823   0.790   0.763   1.094   1.051   1.014   0.686   0.627   0.556
251   L         0.592   0.602   0.638   0.031   0.057   0.083   0.257   0.276   0.316
252   F        -0.782  -0.769  -0.781  -0.763  -0.732  -0.810  -0.722  -0.706  -0.705
253   L         0.952   0.953   0.855   0.539   0.542   0.381   0.910   0.912   0.724
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   V         0.550   0.553   0.607   0.281   0.287   0.367   0.176   0.180   0.257
256   P         0.952   0.951   0.849   1.275   1.277   1.125   0.910   0.909   0.713
257   F        -1.360  -1.358  -1.307  -1.586  -1.579  -1.509  -1.049  -1.046  -0.974
258   N        -1.360  -1.358  -1.307  -1.043  -1.042  -0.964  -1.049  -1.046  -0.974
259   F         0.592   0.585   0.622   0.031   0.012   0.038   0.257   0.243   0.286
260   F        -1.360  -1.358  -1.307  -1.575  -1.571  -1.498  -1.049  -1.046  -0.974
261   L        -0.782  -0.793  -0.767  -1.069  -1.084  -1.031  -0.722  -0.733  -0.690
262   L         0.014   0.001  -0.060  -0.370  -0.390  -0.483  -0.069  -0.088  -0.176
263   L         0.550   0.553   0.607  -0.049  -0.057   0.032   0.176   0.180   0.257
264   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   N        -0.782  -0.770  -0.794  -0.554  -0.536  -0.583  -0.722  -0.707  -0.719
269   V        -1.360  -1.358  -1.307  -1.234  -1.230  -1.155  -1.049  -1.046  -0.974
270   S        -0.204  -0.180  -0.172  -0.091  -0.054  -0.045  -0.396  -0.368  -0.344
271   F        -0.782  -0.776  -0.762  -1.158  -1.144  -1.121  -0.722  -0.715  -0.685
272   E        -1.360  -1.358  -1.307  -1.091  -1.094  -1.012  -1.049  -1.046  -0.974
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   V         0.014  -0.001  -0.073   0.098   0.073  -0.044  -0.069  -0.090  -0.194
275   V        -0.782  -0.800  -0.772  -0.896  -0.935  -0.904  -0.722  -0.741  -0.696
276   G        -0.782  -0.770  -0.794  -0.578  -0.564  -0.583  -0.722  -0.707  -0.719
277   T        -0.782  -0.793  -0.786  -0.526  -0.542  -0.536  -0.722  -0.733  -0.711
278   M        -0.782  -0.769  -0.781  -0.954  -0.946  -0.917  -0.722  -0.706  -0.705
279   L         0.014   0.011  -0.052  -0.387  -0.393  -0.491  -0.069  -0.073  -0.163
280   A        -0.782  -0.770  -0.794  -0.624  -0.610  -0.635  -0.722  -0.707  -0.719
281   G        -0.782  -0.770  -0.794  -0.738  -0.724  -0.737  -0.722  -0.707  -0.719
282   L        -0.782  -0.799  -0.790  -0.911  -0.925  -0.874  -0.722  -0.740  -0.715
283   T         0.014   0.047  -0.062   0.218   0.265   0.090  -0.069  -0.022  -0.178
284   Y         0.014   0.001  -0.085   0.152   0.131  -0.026  -0.069  -0.087  -0.211
285   V         0.014  -0.001  -0.073   0.099   0.076  -0.042  -0.069  -0.090  -0.194
286   W        -0.204  -0.210  -0.195  -0.093  -0.107  -0.084  -0.396  -0.402  -0.372
287   F         1.995   2.000   2.055   1.872   1.882   1.964   2.217   2.224   2.308
288   F         0.014   0.001  -0.085  -0.172  -0.188  -0.366  -0.069  -0.087  -0.211
289   K         1.995   2.000   2.055   2.138   2.145   2.231   2.217   2.224   2.308
290   L         1.995   2.000   2.055   1.578   1.584   1.669   2.217   2.224   2.308
291   R         1.995   2.000   2.055   2.158   2.166   2.252   2.217   2.224   2.308
292   Y         0.952   0.938   0.854   1.077   1.057   0.911   0.910   0.887   0.722
293   L        -0.782  -0.776  -0.762  -0.787  -0.760  -0.763  -0.722  -0.715  -0.685
294   Q         0.592   0.589   0.633   0.424   0.415   0.476   0.257   0.251   0.307
295   S         0.592   0.602   0.638   0.475   0.494   0.536   0.257   0.276   0.316
296   E         0.014   0.001  -0.085   0.393   0.373   0.226  -0.069  -0.087  -0.211
297   S        -0.204  -0.180  -0.191  -0.225  -0.191  -0.210  -0.396  -0.368  -0.367
298   M        -0.204  -0.204  -0.193  -0.197  -0.200  -0.215  -0.396  -0.394  -0.370
299   R         0.014   0.001  -0.085   0.259   0.239   0.097  -0.069  -0.087  -0.211
300   Q        -1.360  -1.358  -1.307  -1.261  -1.266  -1.182  -1.049  -1.046  -0.974
301   I        -0.782  -0.800  -0.772  -0.832  -0.865  -0.827  -0.722  -0.741  -0.696
302   F         0.014   0.036  -0.060   0.134   0.175   0.023  -0.069  -0.037  -0.175
303   K        -1.360  -1.358  -1.307  -0.901  -0.895  -0.820  -1.049  -1.046  -0.974
304   Q         0.952   0.951   0.849   1.132   1.131   1.001   0.910   0.909   0.713
305   Y        -1.360  -1.358  -1.307  -0.847  -0.841  -0.767  -1.049  -1.046  -0.974
306   V        -0.782  -0.770  -0.794  -0.500  -0.477  -0.551  -0.722  -0.707  -0.719
307   L        -0.204  -0.204  -0.175  -0.393  -0.383  -0.339  -0.396  -0.394  -0.349
308   R        -0.204  -0.180  -0.191  -0.011   0.022   0.018  -0.396  -0.368  -0.367
309   L        -0.204  -0.180  -0.174  -0.496  -0.450  -0.468  -0.396  -0.368  -0.347
310   D        -0.204  -0.180  -0.191   0.061   0.090   0.101  -0.396  -0.368  -0.367
311   A        -0.782  -0.770  -0.794  -0.568  -0.551  -0.579  -0.722  -0.707  -0.719
312   Y        -1.360  -1.358  -1.307  -1.170  -1.170  -1.091  -1.049  -1.046  -0.974
313   V        -0.782  -0.770  -0.794  -1.037  -1.020  -1.015  -0.722  -0.707  -0.719
314   S        -0.895  -0.894  -0.841  -1.227  -1.225  -1.149  -0.845  -0.842  -0.769
315   R        -0.782  -0.770  -0.765  -0.610  -0.596  -0.576  -0.722  -0.707  -0.688
316   T        -0.204  -0.203  -0.181  -0.172  -0.172  -0.130  -0.396  -0.393  -0.355
317   L        -1.360  -1.358  -1.307  -1.284  -1.260  -1.205  -1.049  -1.046  -0.974
318   P        -0.782  -0.770  -0.765  -0.990  -0.983  -0.944  -0.722  -0.707  -0.688
319   P         1.995   2.000   2.055   2.245   2.254   2.339   2.217   2.224   2.308
320   Y        -0.782  -0.769  -0.764  -0.593  -0.573  -0.566  -0.722  -0.706  -0.687
321   C        -0.782  -0.769  -0.764  -1.057  -1.053  -1.015  -0.722  -0.706  -0.687
322   S        -0.782  -0.793  -0.767  -0.847  -0.863  -0.835  -0.722  -0.733  -0.690
323   R        -1.360  -1.358  -1.307  -0.912  -0.909  -0.832  -1.049  -1.046  -0.974
324   L         0.014   0.001  -0.060  -0.207  -0.224  -0.281  -0.069  -0.088  -0.176
325   W         0.592   0.589   0.633   0.743   0.737   0.796   0.257   0.251   0.307
326   N        -1.360  -1.358  -1.307  -1.460  -1.466  -1.382  -1.049  -1.046  -0.974
327   G        -0.204  -0.204  -0.193  -0.103  -0.103  -0.092  -0.396  -0.394  -0.370
328   Y        -0.782  -0.770  -0.765  -0.688  -0.671  -0.660  -0.722  -0.707  -0.688
329   K         0.592   0.589   0.633   0.600   0.595   0.658   0.257   0.251   0.307
330   N        -0.782  -0.799  -0.790  -0.657  -0.682  -0.686  -0.722  -0.740  -0.715
331   F        -1.360  -1.358  -1.307  -1.331  -1.322  -1.252  -1.049  -1.046  -0.974
332   V        -0.782  -0.762  -0.760  -0.516  -0.483  -0.484  -0.722  -0.698  -0.682
333   M         0.014   0.036  -0.060  -0.225  -0.198  -0.302  -0.069  -0.037  -0.175
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   T        -0.782  -0.770  -0.794  -0.554  -0.537  -0.579  -0.722  -0.707  -0.719
337   V        -0.782  -0.799  -0.790  -0.950  -0.981  -1.003  -0.722  -0.740  -0.715
338   F        -0.204  -0.203  -0.181  -0.689  -0.689  -0.648  -0.396  -0.393  -0.355
339   W        -0.782  -0.770  -0.765  -0.346  -0.333  -0.326  -0.722  -0.707  -0.688
340   K        -1.360  -1.358  -1.307  -1.170  -1.175  -1.091  -1.049  -1.046  -0.974
341   I         0.952   0.951   0.849   1.032   1.032   0.897   0.910   0.909   0.713
342   P        -0.782  -0.799  -0.790  -0.657  -0.692  -0.710  -0.722  -0.740  -0.715
343   V        -0.204  -0.210  -0.195  -0.575  -0.591  -0.539  -0.396  -0.402  -0.372
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12144
Output conservation file - output/Q12144
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
