1     M         2.047   2.116   2.258   2.251   2.346   2.579   2.254   2.361   2.599
2     F        -0.337  -0.425  -0.389  -0.228  -0.371  -0.278  -0.436  -0.536  -0.480
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     S        -0.080   0.028   0.111  -0.474  -0.313  -0.204  -0.436  -0.294  -0.192
6     F        -0.549  -0.489  -0.451  -0.811  -0.753  -0.678  -0.692  -0.638  -0.555
7     V        -0.678  -0.725  -0.811  -0.656  -0.747  -0.904  -0.564  -0.615  -0.682
8     Q        -0.337  -0.416  -0.369  -0.321  -0.420  -0.394  -0.436  -0.505  -0.448
9     R         2.047   2.116   2.258   2.123   2.218   2.447   2.254   2.361   2.599
10    F        -0.890  -0.935  -0.861  -0.854  -0.922  -0.820  -0.820  -0.852  -0.743
11    Q         0.601   0.540   0.362   0.775   0.682   0.410   0.589   0.483   0.204
12    N        -1.359  -1.313  -1.266  -1.137  -1.100  -0.992  -1.076  -1.026  -0.931
13    V        -0.337  -0.340  -0.354  -0.452  -0.457  -0.484  -0.436  -0.418  -0.429
14    S         0.004   0.150   0.167  -0.234  -0.008  -0.017  -0.308  -0.096  -0.102
15    N         0.132   0.098   0.175  -0.108  -0.156  -0.043  -0.179  -0.220  -0.113
16    Q        -1.230  -1.267  -1.241  -1.109  -1.198  -1.209  -0.948  -0.975  -0.906
17    A         0.601   0.400   0.335   0.698   0.401   0.295   0.589   0.285   0.162
18    F        -1.018  -0.980  -0.906  -1.245  -1.205  -1.100  -0.948  -0.895  -0.788
19    S         0.278   0.402   0.256   0.102   0.278   0.030   0.077   0.252   0.025
20    M        -0.890  -0.727  -0.826  -0.808  -0.582  -0.644  -0.820  -0.627  -0.702
21    G        -0.549  -0.562  -0.462  -0.763  -0.791  -0.644  -0.692  -0.693  -0.565
22    I        -0.420  -0.312  -0.373  -0.504  -0.347  -0.418  -0.564  -0.428  -0.465
23    V        -0.337  -0.390  -0.368  -0.462  -0.535  -0.525  -0.436  -0.481  -0.452
24    M        -0.337  -0.404  -0.388  -0.353  -0.497  -0.441  -0.436  -0.523  -0.480
25    V        -0.890  -0.878  -0.858  -0.844  -0.787  -0.774  -0.820  -0.794  -0.737
26    V        -0.337  -0.095  -0.302  -0.393  -0.045  -0.341  -0.436  -0.128  -0.367
27    F        -0.678  -0.636  -0.513  -0.973  -0.923  -0.750  -0.820  -0.767  -0.616
28    I         0.685   0.754   0.882   0.275   0.390   0.566   0.205   0.307   0.476
29    M        -0.890  -0.858  -0.850  -0.802  -0.776  -0.721  -0.820  -0.769  -0.727
30    A        -0.420  -0.437  -0.395  -0.603  -0.627  -0.554  -0.564  -0.569  -0.491
31    S        -0.890  -0.892  -0.857  -1.043  -1.036  -1.007  -0.820  -0.811  -0.739
32    S        -0.063  -0.171  -0.285  -0.000  -0.151  -0.320  -0.051  -0.201  -0.336
33    Y        -1.359  -1.389  -1.288  -1.208  -1.269  -1.083  -1.076  -1.081  -0.947
34    Y        -0.337  -0.264  -0.366  -0.363  -0.294  -0.382  -0.436  -0.372  -0.455
35    Q         1.306   1.268   1.191   1.420   1.379   1.266   1.357   1.283   1.102
36    L         0.601   0.400   0.335   0.655   0.401   0.310   0.589   0.285   0.162
37    I        -0.678  -0.606  -0.505  -0.775  -0.665  -0.535  -0.820  -0.734  -0.608
38    N        -1.699  -1.668  -1.598  -1.577  -1.522  -1.431  -1.204  -1.165  -1.054
39    N        -0.890  -0.956  -0.859  -0.798  -0.891  -0.756  -0.820  -0.864  -0.739
40    N         0.601   0.400   0.335   0.712   0.458   0.341   0.589   0.285   0.162
41    A         0.132   0.093   0.200  -0.153  -0.206  -0.052  -0.179  -0.201  -0.072
42    F        -0.420  -0.524  -0.415  -0.321  -0.454  -0.282  -0.564  -0.652  -0.513
43    S        -0.337  -0.342  -0.397  -0.433  -0.489  -0.514  -0.436  -0.466  -0.491
44    V         0.601   0.549   0.380   0.625   0.565   0.321   0.589   0.494   0.233
45    -        -1.116  -1.062  -0.962  -1.148  -1.096  -0.933  -1.025  -0.962  -0.834
46    P        -0.890  -0.879  -0.867  -0.816  -0.807  -0.764  -0.820  -0.803  -0.749
47    S        -0.420  -0.469  -0.405  -0.663  -0.749  -0.640  -0.564  -0.601  -0.503
48    N        -0.337  -0.402  -0.370  -0.380  -0.436  -0.396  -0.436  -0.498  -0.456
49    I        -0.678  -0.827  -0.841  -0.525  -0.755  -0.811  -0.564  -0.724  -0.714
50    D        -1.020  -0.984  -0.916  -1.114  -1.068  -0.969  -0.934  -0.886  -0.790
51    N        -0.395  -0.446  -0.438  -0.356  -0.426  -0.424  -0.478  -0.540  -0.528
52    V         0.059   0.064   0.126  -0.154  -0.146  -0.052  -0.251  -0.242  -0.168
53    K        -0.566  -0.551  -0.463  -0.677  -0.643  -0.532  -0.706  -0.678  -0.563
54    T         0.059   0.082   0.124  -0.059  -0.070  -0.018  -0.251  -0.234  -0.175
55    L        -1.388  -1.324  -1.279  -1.404  -1.291  -1.282  -1.092  -1.019  -0.939
56    I        -0.890  -0.790  -0.834  -0.936  -0.810  -0.871  -0.820  -0.710  -0.717
57    N        -1.699  -1.684  -1.614  -1.662  -1.652  -1.572  -1.204  -1.177  -1.065
58    V        -1.359  -1.309  -1.273  -1.248  -1.152  -1.114  -1.076  -1.021  -0.936
59    R        -0.337  -0.300  -0.343  -0.240  -0.145  -0.240  -0.436  -0.364  -0.415
60    T        -1.699  -1.684  -1.614  -1.484  -1.506  -1.351  -1.204  -1.177  -1.065
61    S        -0.063  -0.252  -0.321   0.027  -0.237  -0.323  -0.051  -0.296  -0.382
62    R        -0.337  -0.300  -0.343  -0.184  -0.099  -0.179  -0.436  -0.364  -0.415
63    Y        -1.230  -1.185  -1.232  -0.821  -0.790  -0.822  -0.948  -0.900  -0.898
64    F         1.306   1.436   1.222   1.466   1.626   1.373   1.357   1.558   1.161
65    G         0.601   0.400   0.335   0.835   0.575   0.466   0.589   0.285   0.162
66    S         0.278   0.236   0.201   0.136   0.046   0.012   0.077  -0.009  -0.064
67    Q        -1.388  -1.377  -1.291  -1.464  -1.456  -1.343  -1.092  -1.070  -0.948
68    R        -0.999  -0.935  -0.904  -0.945  -0.813  -0.798  -0.924  -0.845  -0.781
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    G        -0.999  -1.038  -0.933  -0.934  -1.018  -0.883  -0.924  -0.943  -0.808
71    K        -0.063  -0.129  -0.294  -0.018  -0.121  -0.375  -0.051  -0.144  -0.348
72    A        -0.678  -0.773  -0.809  -0.323  -0.475  -0.540  -0.564  -0.670  -0.680
73    K        -0.063  -0.252  -0.321   0.012  -0.239  -0.361  -0.051  -0.296  -0.382
74    E         1.306   1.184   1.167   1.448   1.294   1.279   1.357   1.138   1.056
75    N         0.278   0.202   0.186   0.239   0.108   0.076   0.077  -0.069  -0.088
76    M        -0.549  -0.448  -0.425  -0.621  -0.485  -0.459  -0.692  -0.560  -0.522
77    K        -0.890  -0.958  -0.859  -0.874  -0.968  -0.827  -0.820  -0.866  -0.741
78    I         0.601   0.497   0.363   0.675   0.528   0.301   0.589   0.423   0.205
79    K        -0.890  -0.833  -0.842  -0.839  -0.747  -0.750  -0.820  -0.739  -0.718
80    F         2.047   2.116   2.258   1.992   2.079   2.311   2.254   2.361   2.599
81    D         0.278   0.163   0.185   0.262   0.063   0.056   0.077  -0.105  -0.090
82    L         0.601   0.475   0.337   0.662   0.515   0.327   0.589   0.393   0.166
83    N        -0.063   0.208  -0.186   0.151   0.519  -0.036  -0.051   0.307  -0.207
84    T        -0.337  -0.167  -0.315  -0.397  -0.137  -0.378  -0.436  -0.207  -0.386
85    D         2.047   2.116   2.258   2.051   2.148   2.372   2.254   2.361   2.599
86    L         1.306   1.353   1.192   1.248   1.321   1.106   1.357   1.426   1.104
87    T         0.942   1.093   1.017   0.691   0.916   0.762   0.717   0.973   0.759
88    P        -0.063  -0.252  -0.321   0.269  -0.009  -0.123  -0.051  -0.296  -0.382
89    L         2.047   2.116   2.258   1.888   1.989   2.204   2.254   2.361   2.599
90    F         1.306   1.184   1.167   1.378   1.224   1.225   1.357   1.138   1.056
91    N         0.601   0.400   0.335   0.698   0.436   0.312   0.589   0.285   0.162
92    W         2.047   2.116   2.258   2.166   2.262   2.491   2.254   2.361   2.599
93    N         2.047   2.116   2.258   1.970   2.080   2.289   2.254   2.361   2.599
94    T         2.047   2.116   2.258   1.921   2.011   2.238   2.254   2.361   2.599
95    K         2.047   2.116   2.258   1.880   1.985   2.196   2.254   2.361   2.599
96    Q         0.601   0.497   0.363   0.820   0.697   0.498   0.589   0.423   0.205
97    V         0.601   0.836   0.425   0.591   0.891   0.334   0.589   0.929   0.302
98    F         1.306   1.184   1.167   1.337   1.161   1.136   1.357   1.138   1.056
99    V         0.278   0.400   0.257   0.126   0.277   0.078   0.077   0.237   0.023
100   Y         2.047   2.116   2.258   2.105   2.194   2.428   2.254   2.361   2.599
101   L         0.942   0.935   0.953   0.696   0.665   0.637   0.717   0.674   0.627
102   T         1.306   1.184   1.167   1.266   1.094   1.064   1.357   1.138   1.056
103   A         2.047   2.116   2.258   1.985   2.071   2.304   2.254   2.361   2.599
104   E         0.278   0.272   0.216   0.258   0.209   0.099   0.077   0.044  -0.043
105   Y         1.306   1.268   1.191   1.490   1.447   1.373   1.357   1.283   1.102
106   N        -0.890  -0.923  -0.875  -0.727  -0.781  -0.715  -0.820  -0.835  -0.754
107   S        -0.063  -0.188  -0.284   0.160  -0.038  -0.212  -0.051  -0.221  -0.335
108   T        -0.890  -0.978  -0.892  -0.939  -1.042  -0.922  -0.820  -0.885  -0.771
109   E        -0.890  -0.951  -0.879  -0.819  -0.902  -0.796  -0.820  -0.858  -0.757
110   K        -1.018  -0.927  -0.911  -0.916  -0.746  -0.736  -0.948  -0.849  -0.791
111   -        -0.566  -0.536  -0.463  -0.581  -0.548  -0.430  -0.706  -0.658  -0.562
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   I        -1.018  -1.062  -0.919  -1.146  -1.180  -0.984  -0.948  -0.963  -0.798
116   T        -1.018  -1.035  -0.913  -1.185  -1.207  -1.011  -0.948  -0.941  -0.793
117   S         1.306   1.436   1.222   1.313   1.498   1.202   1.357   1.558   1.161
118   E        -0.337  -0.305  -0.341  -0.301  -0.221  -0.306  -0.436  -0.379  -0.413
119   V         0.132   0.124   0.195  -0.135  -0.139  -0.033  -0.179  -0.174  -0.083
120   T         0.942   0.854   0.931   0.729   0.534   0.624   0.717   0.512   0.581
121   F        -0.890  -0.817  -0.838  -0.881  -0.793  -0.814  -0.820  -0.734  -0.719
122   W         2.047   2.116   2.258   2.166   2.262   2.491   2.254   2.361   2.599
123   D         2.047   2.116   2.258   2.051   2.148   2.372   2.254   2.361   2.599
124   K         0.601   0.572   0.393   0.612   0.583   0.322   0.589   0.542   0.253
125   I         2.047   2.116   2.258   1.981   2.085   2.300   2.254   2.361   2.599
126   I         1.306   1.184   1.167   1.327   1.172   1.127   1.357   1.138   1.056
127   K        -0.337  -0.384  -0.374  -0.439  -0.506  -0.501  -0.436  -0.473  -0.457
128   S        -0.063   0.117  -0.196  -0.024   0.221  -0.222  -0.051   0.188  -0.220
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   K         0.132   0.151   0.179  -0.004   0.047   0.120  -0.179  -0.163  -0.108
157   D        -0.420  -0.401  -0.387  -0.419  -0.387  -0.371  -0.564  -0.534  -0.485
158   D        -0.337  -0.414  -0.396  -0.214  -0.329  -0.301  -0.436  -0.529  -0.491
159   A         0.278   0.171   0.198   0.202   0.007   0.040   0.077  -0.092  -0.069
160   V        -1.359  -1.245  -1.265  -1.337  -1.175  -1.186  -1.076  -0.960  -0.930
161   I        -0.337  -0.402  -0.370  -0.368  -0.420  -0.391  -0.436  -0.498  -0.456
162   D        -1.699  -1.668  -1.598  -1.585  -1.570  -1.446  -1.204  -1.165  -1.054
163   V         0.601   0.549   0.380   0.644   0.593   0.357   0.589   0.494   0.233
164   N        -0.678  -0.488  -0.736  -0.632  -0.351  -0.743  -0.564  -0.337  -0.601
165   D        -0.420  -0.337  -0.376  -0.385  -0.269  -0.272  -0.564  -0.467  -0.472
166   L        -0.890  -0.904  -0.869  -0.835  -0.867  -0.835  -0.820  -0.821  -0.750
167   R        -0.890  -0.915  -0.853  -0.814  -0.839  -0.778  -0.820  -0.824  -0.734
168   S        -0.337  -0.320  -0.345  -0.345  -0.302  -0.328  -0.436  -0.391  -0.424
169   K         1.306   1.184   1.167   1.238   1.092   1.051   1.357   1.138   1.056
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   Y         1.306   1.184   1.167   1.499   1.348   1.355   1.357   1.138   1.056
174   S        -0.337  -0.414  -0.396  -0.380  -0.488  -0.449  -0.436  -0.529  -0.491
175   I        -0.549  -0.606  -0.466  -0.810  -0.887  -0.696  -0.692  -0.737  -0.571
176   W        -0.063  -0.233  -0.302   0.279   0.018  -0.095  -0.051  -0.274  -0.358
177   D         0.601   0.400   0.335   0.833   0.574   0.499   0.589   0.285   0.162
178   I        -1.018  -1.063  -0.916  -1.100  -1.120  -0.930  -0.948  -0.963  -0.796
179   E         0.942   0.854   0.931   0.877   0.679   0.760   0.717   0.512   0.581
180   D        -1.699  -1.684  -1.614  -1.437  -1.420  -1.328  -1.204  -1.177  -1.065
181   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   K         0.132   0.087   0.185  -0.188  -0.207  -0.087  -0.179  -0.212  -0.092
183   F         0.601   0.550   0.368   0.703   0.628   0.354   0.589   0.510   0.214
184   E        -0.890  -0.901  -0.874  -0.744  -0.784  -0.756  -0.820  -0.824  -0.757
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   G        -0.678  -0.637  -0.763  -0.383  -0.330  -0.525  -0.564  -0.513  -0.630
187   K         0.132   0.101   0.176   0.020  -0.029   0.078  -0.179  -0.214  -0.112
188   D         0.132   0.216   0.214   0.016   0.164   0.168  -0.179  -0.045  -0.051
189   L         0.132   0.126   0.184  -0.127  -0.131  -0.058  -0.179  -0.170  -0.097
190   V         0.942   1.101   1.031   0.729   0.968   0.822   0.717   0.989   0.787
191   F        -0.420  -0.524  -0.415  -0.569  -0.702  -0.541  -0.564  -0.652  -0.513
192   K        -0.337  -0.385  -0.371  -0.367  -0.445  -0.405  -0.436  -0.491  -0.460
193   L         2.047   2.116   2.258   1.888   1.989   2.204   2.254   2.361   2.599
194   H         0.278   0.478   0.311   0.498   0.787   0.564   0.077   0.381   0.119
195   W         1.306   1.268   1.191   1.542   1.502   1.416   1.357   1.283   1.102
196   N         1.306   1.184   1.167   1.321   1.171   1.126   1.357   1.138   1.056
197   V         0.132   0.230   0.195  -0.134  -0.034  -0.059  -0.179  -0.082  -0.089
198   Q         1.306   1.184   1.167   1.413   1.251   1.211   1.357   1.138   1.056
199   P         2.047   2.116   2.258   2.141   2.239   2.466   2.254   2.361   2.599
200   W        -0.337  -0.316  -0.362  -0.072  -0.067  -0.107  -0.436  -0.401  -0.444
201   V        -0.063  -0.092  -0.271   0.045   0.009  -0.229  -0.051  -0.101  -0.318
202   G         2.047   2.116   2.258   2.087   2.190   2.410   2.254   2.361   2.599
203   L        -1.018  -0.940  -0.903  -1.020  -0.933  -0.869  -0.948  -0.862  -0.783
204   L         1.306   1.378   1.212   1.232   1.338   1.104   1.357   1.466   1.141
205   T         0.132   0.058   0.171  -0.112  -0.222  -0.068  -0.179  -0.261  -0.116
206   Y        -0.549  -0.533  -0.465  -0.520  -0.486  -0.383  -0.692  -0.668  -0.569
207   G         1.306   1.268   1.191   1.456   1.422   1.322   1.357   1.283   1.102
208   E        -0.549  -0.591  -0.455  -0.620  -0.679  -0.493  -0.692  -0.719  -0.558
209   T        -0.063  -0.233  -0.302   0.045  -0.192  -0.309  -0.051  -0.274  -0.358
210   V        -1.018  -1.002  -0.912  -1.045  -1.024  -0.877  -0.948  -0.919  -0.792
211   G        -0.063  -0.005  -0.221   0.224   0.303   0.001  -0.051   0.022  -0.253
212   N        -1.230  -1.091  -1.194  -1.154  -0.950  -1.113  -0.948  -0.803  -0.863
213   Y        -0.999  -0.905  -0.886  -0.876  -0.746  -0.719  -0.924  -0.826  -0.767
214   T        -0.999  -0.932  -0.890  -0.990  -0.896  -0.827  -0.924  -0.851  -0.770
215   L        -0.999  -0.926  -0.901  -1.025  -0.897  -0.886  -0.924  -0.840  -0.778
216   T        -0.852  -0.827  -0.835  -0.791  -0.741  -0.766  -0.757  -0.730  -0.708
217   V        -0.463  -0.450  -0.415  -0.623  -0.603  -0.568  -0.590  -0.557  -0.506
218   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -         0.179   0.398   0.216  -0.015   0.308   0.005  -0.041   0.283  -0.024
245   -        -0.571  -0.552  -0.471  -0.668  -0.635  -0.519  -0.697  -0.675  -0.568
246   -         0.482   0.410   0.328   0.471   0.389   0.251   0.414   0.293   0.151
247   -         1.241   1.324   1.192   1.155   1.280   1.093   1.250   1.377   1.103
248   -        -0.999  -0.957  -0.901  -0.921  -0.851  -0.764  -0.924  -0.874  -0.780
249   -        -1.388  -1.346  -1.290  -1.396  -1.355  -1.265  -1.092  -1.044  -0.948
250   -        -0.999  -0.949  -0.889  -0.954  -0.910  -0.806  -0.924  -0.866  -0.769
251   -         0.169   0.108   0.170  -0.012  -0.100  -0.023  -0.088  -0.185  -0.111
252   -        -1.020  -1.022  -0.923  -0.940  -0.927  -0.803  -0.934  -0.924  -0.797
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   V        -0.999  -0.932  -0.890  -1.162  -1.063  -1.004  -0.924  -0.848  -0.770
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12133
Output conservation file - output/Q12133
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
