1     M         1.829   1.863   1.953   2.100   2.149   2.295   2.050   2.102   2.250
2     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    Q        -0.459  -0.308  -0.418  -0.523  -0.318  -0.438  -0.595  -0.437  -0.515
11    A         0.188   0.227   0.139   0.135   0.184   0.063   0.006   0.071  -0.083
12    K         1.829   1.863   1.953   1.788   1.837   1.985   2.050   2.102   2.250
13    L         0.804   0.724   0.769   0.454   0.320   0.383   0.608   0.433   0.460
14    A        -0.894  -0.921  -0.878  -0.882  -0.945  -0.848  -0.835  -0.858  -0.780
15    K         0.565   0.602   0.703   0.347   0.414   0.572   0.127   0.180   0.321
16    T         0.488   0.326   0.226   0.745   0.508   0.341   0.487   0.242   0.068
17    L         0.053   0.046   0.090  -0.247  -0.177  -0.135  -0.234  -0.210  -0.157
18    Q        -0.382  -0.468  -0.455  -0.389  -0.556  -0.575  -0.475  -0.580  -0.547
19    R         1.829   1.863   1.953   2.024   2.068   2.219   2.050   2.102   2.250
20    F         0.188   0.113   0.082   0.093  -0.085  -0.151   0.006  -0.129  -0.171
21    E        -1.329  -1.313  -1.244  -1.177  -1.124  -1.038  -1.076  -1.048  -0.946
22    N        -1.014  -0.971  -0.910  -1.166  -1.118  -1.007  -0.956  -0.908  -0.811
23    K         0.584   0.613   0.708   0.370   0.411   0.561   0.166   0.205   0.333
24    I         1.829   1.863   1.953   1.913   1.965   2.108   2.050   2.102   2.250
25    K        -0.499  -0.417  -0.455  -0.625  -0.515  -0.565  -0.619  -0.521  -0.548
26    A         0.087   0.004   0.055  -0.066  -0.214  -0.136  -0.148  -0.263  -0.205
27    G         1.829   1.863   1.953   1.898   1.944   2.093   2.050   2.102   2.250
28    D        -0.698  -0.749  -0.830  -0.517  -0.592  -0.761  -0.595  -0.648  -0.723
29    Y         0.053  -0.011   0.065  -0.013  -0.081   0.035  -0.234  -0.310  -0.206
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    Y         1.829   1.863   1.953   1.897   1.955   2.093   2.050   2.102   2.250
34    E         1.142   1.154   0.997   1.241   1.259   1.047   1.209   1.222   0.915
35    A         1.142   1.050   0.983   1.185   1.045   0.970   1.209   1.047   0.888
36    H         1.142   1.084   0.991   1.478   1.408   1.268   1.209   1.105   0.903
37    Q         1.829   1.863   1.953   1.965   2.018   2.160   2.050   2.102   2.250
38    T        -0.128  -0.285  -0.378   0.195  -0.028  -0.182  -0.114  -0.320  -0.441
39    L         0.488   0.418   0.244   0.345   0.258   0.021   0.487   0.380   0.095
40    R         1.829   1.863   1.953   2.024   2.068   2.219   2.050   2.102   2.250
41    T         1.142   1.084   0.991   1.315   1.230   1.061   1.209   1.105   0.903
42    I         0.188   0.071   0.083   0.189  -0.013  -0.041   0.006  -0.166  -0.167
43    A         0.188   0.116   0.117   0.157   0.041   0.059   0.006  -0.091  -0.110
44    N         1.142   1.084   0.991   1.310   1.237   1.090   1.209   1.105   0.903
45    R         1.829   1.863   1.953   2.024   2.068   2.219   2.050   2.102   2.250
46    Y         1.142   1.050   0.983   1.292   1.185   1.083   1.209   1.047   0.888
47    V         1.142   1.084   0.991   1.333   1.263   1.137   1.209   1.105   0.903
48    R         0.623   0.738   0.784   0.423   0.606   0.673   0.247   0.461   0.492
49    S         0.053   0.106   0.105  -0.166  -0.076  -0.053  -0.234  -0.141  -0.143
50    K         0.488   0.439   0.260   0.567   0.501   0.240   0.487   0.411   0.121
51    S        -1.014  -1.014  -0.920  -1.099  -1.084  -0.958  -0.956  -0.939  -0.818
52    Y         0.488   0.326   0.226   0.750   0.557   0.426   0.487   0.242   0.068
53    E        -0.894  -0.868  -0.866  -0.792  -0.744  -0.750  -0.835  -0.806  -0.768
54    H        -0.579  -0.535  -0.476  -0.588  -0.529  -0.451  -0.715  -0.645  -0.571
55    A         1.142   1.238   1.010   1.172   1.279   0.989   1.209   1.358   0.939
56    I         0.488   0.400   0.253   0.731   0.619   0.407   0.487   0.351   0.110
57    E         0.053   0.025   0.087  -0.091  -0.113  -0.027  -0.234  -0.247  -0.169
58    L         0.488   0.418   0.244   0.338   0.249   0.007   0.487   0.380   0.095
59    I         0.623   0.738   0.784   0.158   0.343   0.407   0.247   0.461   0.492
60    S         0.053   0.167   0.085  -0.090   0.080  -0.022  -0.234  -0.092  -0.176
61    Q        -0.382  -0.386  -0.446  -0.286  -0.340  -0.402  -0.475  -0.502  -0.538
62    G         0.488   0.494   0.271   0.671   0.679   0.348   0.487   0.488   0.138
63    A         0.623   0.630   0.714   0.320   0.301   0.437   0.247   0.240   0.344
64    L        -1.645  -1.663  -1.560  -1.760  -1.745  -1.580  -1.196  -1.196  -1.069
65    S        -0.579  -0.621  -0.509  -0.724  -0.778  -0.612  -0.715  -0.749  -0.611
66    F         0.623   0.738   0.784   0.144   0.333   0.395   0.247   0.461   0.492
67    L         0.488   0.408   0.254   0.311   0.206  -0.027   0.487   0.362   0.111
68    K        -0.128  -0.145  -0.314  -0.023  -0.060  -0.302  -0.114  -0.142  -0.359
69    A        -0.382  -0.396  -0.424  -0.413  -0.444  -0.474  -0.475  -0.490  -0.505
70    K         0.488   0.326   0.226   0.561   0.332   0.173   0.487   0.242   0.068
71    Q         0.188   0.143   0.127   0.241   0.170   0.119   0.006  -0.054  -0.095
72    G        -0.382  -0.448  -0.448  -0.308  -0.395  -0.410  -0.475  -0.549  -0.540
73    G         0.623   0.647   0.720   0.403   0.423   0.527   0.247   0.276   0.358
74    S         1.142   1.084   0.991   1.186   1.113   0.969   1.209   1.105   0.903
75    G         0.623   0.669   0.732   0.367   0.421   0.526   0.247   0.321   0.383
76    T        -0.128  -0.193  -0.332   0.001  -0.113  -0.312  -0.114  -0.209  -0.382
77    D         1.829   1.863   1.953   1.902   1.956   2.097   2.050   2.102   2.250
78    L         1.829   1.863   1.953   1.549   1.597   1.746   2.050   2.102   2.250
79    I         0.188   0.113   0.082   0.208   0.048   0.006   0.006  -0.129  -0.171
80    F        -0.894  -0.903  -0.904  -0.906  -0.917  -0.965  -0.835  -0.841  -0.803
81    Y         1.142   1.084   0.991   1.234   1.158   0.981   1.209   1.105   0.903
82    L         0.488   0.387   0.241   0.368   0.247   0.058   0.487   0.332   0.090
83    L         0.188   0.143   0.127  -0.103  -0.156  -0.174   0.006  -0.054  -0.095
84    E        -0.382  -0.417  -0.453  -0.334  -0.406  -0.429  -0.475  -0.532  -0.546
85    V         1.142   1.168   1.006   1.325   1.366   1.147   1.209   1.246   0.932
86    Y         1.829   1.863   1.953   1.897   1.955   2.093   2.050   2.102   2.250
87    D        -0.382  -0.466  -0.452  -0.352  -0.497  -0.482  -0.475  -0.577  -0.546
88    L        -1.014  -1.049  -0.926  -1.235  -1.253  -1.074  -0.956  -0.968  -0.824
89    A        -0.128  -0.174  -0.336  -0.037  -0.124  -0.369  -0.114  -0.175  -0.387
90    E        -1.014  -1.015  -0.909  -1.113  -1.114  -0.958  -0.956  -0.941  -0.810
91    V        -0.459  -0.496  -0.438  -0.417  -0.456  -0.363  -0.595  -0.623  -0.534
92    K        -0.382  -0.429  -0.417  -0.457  -0.543  -0.537  -0.475  -0.521  -0.503
93    V        -0.382  -0.476  -0.428  -0.160  -0.299  -0.211  -0.475  -0.573  -0.516
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    D        -0.066  -0.028   0.009  -0.200  -0.133  -0.110  -0.354  -0.301  -0.268
100   D        -1.329  -1.334  -1.265  -1.488  -1.557  -1.438  -1.076  -1.067  -0.963
101   I        -1.210  -1.090  -1.199  -1.014  -0.846  -1.020  -0.956  -0.835  -0.905
102   S        -0.128  -0.201  -0.348  -0.008  -0.109  -0.353  -0.114  -0.212  -0.403
103   V        -0.144  -0.121  -0.023  -0.320  -0.292  -0.136  -0.475  -0.442  -0.316
104   A        -1.014  -0.972  -0.910  -1.296  -1.245  -1.109  -0.956  -0.910  -0.811
105   R         0.804   0.833   0.831   0.871   0.909   0.871   0.608   0.649   0.588
106   L         0.488   0.387   0.241   0.313   0.166  -0.045   0.487   0.332   0.090
107   V        -0.579  -0.510  -0.504  -0.806  -0.766  -0.721  -0.715  -0.650  -0.606
108   R        -1.329  -1.255  -1.248  -1.117  -1.006  -1.004  -1.076  -0.999  -0.950
109   L         1.142   1.084   0.991   0.976   0.916   0.820   1.209   1.105   0.903
110   I         0.565   0.596   0.698   0.101   0.139   0.300   0.127   0.169   0.311
111   A        -1.329  -1.336  -1.265  -1.209  -1.208  -1.104  -1.076  -1.069  -0.963
112   E         0.488   0.603   0.300   0.325   0.480   0.069   0.487   0.651   0.183
113   L        -0.144  -0.064  -0.003  -0.547  -0.394  -0.324  -0.475  -0.367  -0.291
114   D         0.053   0.009   0.058   0.044  -0.010   0.069  -0.234  -0.287  -0.215
115   P        -1.645  -1.635  -1.535  -1.388  -1.404  -1.232  -1.196  -1.177  -1.051
116   S        -1.329  -1.255  -1.248  -1.121  -1.012  -0.994  -1.076  -0.999  -0.950
117   E         0.804   0.833   0.831   0.744   0.785   0.761   0.608   0.649   0.588
118   P         1.142   1.050   0.983   1.440   1.313   1.218   1.209   1.047   0.888
119   N        -0.579  -0.628  -0.525  -0.640  -0.719  -0.572  -0.715  -0.757  -0.628
120   L         0.804   0.724   0.769   0.488   0.361   0.436   0.608   0.433   0.460
121   K        -0.128  -0.118  -0.332   0.000   0.016  -0.293  -0.114  -0.099  -0.382
122   D         0.188   0.071   0.083   0.187   0.004  -0.006   0.006  -0.166  -0.167
123   V        -1.014  -1.049  -0.926  -1.174  -1.216  -1.021  -0.956  -0.968  -0.824
124   I        -0.382  -0.300  -0.403  -0.351  -0.244  -0.390  -0.475  -0.377  -0.480
125   T         0.053   0.123   0.099  -0.078   0.039   0.019  -0.234  -0.110  -0.143
126   G        -1.210  -1.301  -1.254  -0.990  -1.126  -1.078  -0.956  -1.032  -0.954
127   M        -0.894  -0.984  -0.918  -0.803  -1.000  -0.929  -0.835  -0.910  -0.815
128   N        -0.894  -0.939  -0.901  -0.978  -1.090  -1.041  -0.835  -0.872  -0.800
129   N        -0.698  -0.824  -0.846  -0.454  -0.649  -0.715  -0.595  -0.733  -0.739
130   W         1.829   1.863   1.953   2.142   2.191   2.337   2.050   2.102   2.250
131   S         1.829   1.863   1.953   1.815   1.870   2.011   2.050   2.102   2.250
132   I        -1.329  -1.301  -1.246  -1.189  -1.146  -1.056  -1.076  -1.037  -0.948
133   K         0.488   0.408   0.254   0.567   0.454   0.229   0.487   0.362   0.111
134   F        -0.894  -0.897  -0.860  -0.756  -0.769  -0.724  -0.835  -0.819  -0.758
135   S        -0.459  -0.410  -0.452  -0.527  -0.425  -0.474  -0.595  -0.523  -0.545
136   E        -0.499  -0.567  -0.501  -0.469  -0.555  -0.453  -0.619  -0.691  -0.600
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   Y        -0.274  -0.225  -0.364  -0.133  -0.054  -0.290  -0.305  -0.244  -0.424
139   K         0.377   0.248   0.153   0.442   0.264   0.105   0.323   0.121  -0.046
140   F        -0.128  -0.285  -0.378   0.066  -0.165  -0.344  -0.114  -0.320  -0.441
141   G         1.829   1.863   1.953   1.902   1.952   2.097   2.050   2.102   2.250
142   D         1.829   1.863   1.953   1.902   1.956   2.097   2.050   2.102   2.250
143   P        -0.382  -0.453  -0.448  -0.114  -0.238  -0.245  -0.475  -0.553  -0.536
144   Y        -1.014  -0.943  -0.908  -0.999  -0.900  -0.831  -0.956  -0.884  -0.809
145   L         1.142   1.050   0.983   0.938   0.823   0.735   1.209   1.047   0.888
146   H         1.829   1.863   1.953   2.094   2.145   2.289   2.050   2.102   2.250
147   N        -0.459  -0.456  -0.451  -0.334  -0.304  -0.313  -0.595  -0.582  -0.547
148   T        -0.579  -0.501  -0.485  -0.860  -0.784  -0.712  -0.715  -0.634  -0.585
149   I        -0.144  -0.138  -0.027  -0.292  -0.277  -0.118  -0.475  -0.466  -0.323
150   G         0.804   0.795   0.778   0.756   0.723   0.655   0.608   0.574   0.480
151   S        -0.382  -0.241  -0.388  -0.280  -0.058  -0.294  -0.475  -0.294  -0.466
152   K        -0.128  -0.285  -0.378  -0.042  -0.275  -0.439  -0.114  -0.320  -0.441
153   L         0.053   0.071   0.093  -0.280  -0.178  -0.169  -0.234  -0.178  -0.152
154   L        -0.066  -0.086  -0.012  -0.518  -0.564  -0.425  -0.354  -0.390  -0.301
155   E        -0.459  -0.366  -0.432  -0.608  -0.489  -0.552  -0.595  -0.494  -0.528
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   G        -0.894  -0.976  -0.905  -0.812  -0.931  -0.817  -0.835  -0.904  -0.804
182   D        -0.579  -0.542  -0.495  -0.674  -0.591  -0.522  -0.715  -0.653  -0.594
183   F        -0.894  -0.744  -0.853  -1.037  -0.776  -0.976  -0.835  -0.668  -0.755
184   V        -1.014  -1.024  -0.922  -0.889  -0.880  -0.732  -0.956  -0.948  -0.820
185   Y         0.053   0.009   0.058  -0.108  -0.185  -0.095  -0.234  -0.287  -0.215
186   E        -0.128  -0.201  -0.348   0.032  -0.081  -0.316  -0.114  -0.212  -0.403
187   A         1.829   1.863   1.953   1.800   1.827   1.996   2.050   2.102   2.250
188   E         1.829   1.863   1.953   1.855   1.900   2.051   2.050   2.102   2.250
189   R        -0.459  -0.410  -0.452  -0.571  -0.518  -0.611  -0.595  -0.523  -0.545
190   Y         0.053   0.123   0.099   0.119   0.278   0.232  -0.234  -0.110  -0.143
191   F         0.188   0.282   0.135  -0.122  -0.000  -0.193   0.006   0.119  -0.092
192   M        -0.382  -0.285  -0.364  -0.273  -0.122  -0.268  -0.475  -0.330  -0.427
193   L         1.829   1.863   1.953   1.549   1.597   1.746   2.050   2.102   2.250
194   G         1.829   1.863   1.953   1.902   1.952   2.097   2.050   2.102   2.250
195   T         1.142   1.050   0.983   1.368   1.251   1.154   1.209   1.047   0.888
196   H        -0.382  -0.473  -0.452  -0.211  -0.384  -0.370  -0.475  -0.586  -0.544
197   D         0.188   0.194   0.158   0.152   0.176   0.096   0.006   0.037  -0.045
198   S         1.829   1.863   1.953   1.815   1.870   2.011   2.050   2.102   2.250
199   M        -0.579  -0.479  -0.486  -0.681  -0.561  -0.569  -0.715  -0.584  -0.583
200   I        -1.210  -1.148  -1.207  -0.867  -0.787  -0.903  -0.956  -0.897  -0.913
201   K        -1.645  -1.663  -1.560  -1.627  -1.673  -1.507  -1.196  -1.196  -1.069
202   Y         0.804   0.774   0.784   0.673   0.604   0.545   0.608   0.533   0.492
203   V        -0.579  -0.615  -0.523  -0.580  -0.629  -0.493  -0.715  -0.746  -0.626
204   D        -0.894  -0.984  -0.918  -0.753  -0.870  -0.771  -0.835  -0.910  -0.815
205   L        -0.698  -0.815  -0.845  -0.749  -0.886  -0.906  -0.595  -0.723  -0.739
206   L         0.488   0.326   0.226   0.355   0.146   0.014   0.487   0.242   0.068
207   W        -0.459  -0.426  -0.441  -0.301  -0.260  -0.281  -0.595  -0.539  -0.531
208   D        -0.894  -0.922  -0.883  -0.814  -0.850  -0.809  -0.835  -0.858  -0.782
209   W         1.829   1.863   1.953   2.136   2.185   2.330   2.050   2.102   2.250
210   L        -0.459  -0.388  -0.415  -0.583  -0.459  -0.530  -0.595  -0.518  -0.511
211   C        -1.329  -1.272  -1.230  -1.146  -1.110  -0.990  -1.076  -1.020  -0.937
212   Q        -0.499  -0.567  -0.502  -0.515  -0.631  -0.553  -0.619  -0.692  -0.601
213   V        -0.382  -0.243  -0.388  -0.423  -0.214  -0.425  -0.475  -0.296  -0.467
214   D        -1.014  -0.992  -0.907  -1.057  -1.026  -0.896  -0.956  -0.925  -0.809
215   D        -1.210  -1.260  -1.223  -0.962  -1.041  -0.992  -0.956  -0.997  -0.927
216   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   D        -1.014  -0.937  -0.914  -0.960  -0.851  -0.809  -0.956  -0.879  -0.813
219   S        -0.894  -0.984  -0.918  -0.785  -0.876  -0.770  -0.835  -0.910  -0.815
220   T        -0.144  -0.118  -0.030  -0.347  -0.300  -0.171  -0.475  -0.440  -0.327
221   V        -0.579  -0.483  -0.492  -0.554  -0.432  -0.432  -0.715  -0.606  -0.590
222   A        -0.579  -0.609  -0.505  -0.636  -0.688  -0.505  -0.715  -0.734  -0.606
223   E        -1.329  -1.297  -1.251  -1.410  -1.375  -1.281  -1.076  -1.036  -0.953
224   F         1.142   1.276   1.019   1.286   1.466   1.127   1.209   1.417   0.957
225   F        -1.014  -0.939  -0.915  -1.204  -1.123  -1.040  -0.956  -0.877  -0.814
226   S         0.188   0.089   0.099   0.116  -0.048  -0.046   0.006  -0.147  -0.146
227   R         1.829   1.863   1.953   2.024   2.068   2.219   2.050   2.102   2.250
228   L        -0.894  -0.859  -0.868  -0.989  -0.900  -0.880  -0.835  -0.781  -0.765
229   V         0.623   0.643   0.714   0.500   0.527   0.617   0.247   0.267   0.344
230   F        -0.894  -0.761  -0.858  -1.029  -0.859  -0.930  -0.835  -0.680  -0.756
231   N         0.488   0.418   0.244   0.744   0.661   0.404   0.487   0.380   0.095
232   Y         1.829   1.863   1.953   1.897   1.955   2.093   2.050   2.102   2.250
233   L         0.488   0.516   0.262   0.293   0.332  -0.048   0.487   0.527   0.124
234   F        -0.579  -0.586  -0.524  -0.820  -0.880  -0.779  -0.715  -0.719  -0.626
235   I        -0.459  -0.497  -0.462  -0.719  -0.798  -0.721  -0.595  -0.617  -0.556
236   S        -1.329  -1.228  -1.245  -1.355  -1.228  -1.225  -1.076  -0.986  -0.948
237   N         1.829   1.863   1.953   1.939   1.995   2.134   2.050   2.102   2.250
238   I         0.188   0.080   0.096   0.189   0.003  -0.016   0.006  -0.152  -0.151
239   S        -1.329  -1.240  -1.249  -1.267  -1.124  -1.152  -1.076  -0.997  -0.951
240   F        -0.894  -0.954  -0.880  -0.865  -0.951  -0.859  -0.835  -0.876  -0.779
241   A         0.804   0.833   0.831   0.702   0.724   0.724   0.608   0.649   0.588
242   H        -1.961  -1.914  -1.812  -1.633  -1.520  -1.421  -1.316  -1.271  -1.144
243   E        -0.128  -0.285  -0.378   0.075  -0.149  -0.289  -0.114  -0.320  -0.441
244   S        -0.382  -0.286  -0.379  -0.385  -0.231  -0.361  -0.475  -0.346  -0.456
245   K        -1.645  -1.663  -1.560  -1.702  -1.770  -1.595  -1.196  -1.196  -1.069
246   D        -1.329  -1.315  -1.232  -1.198  -1.159  -1.049  -1.076  -1.051  -0.938
247   I        -1.329  -1.262  -1.235  -1.340  -1.218  -1.234  -1.076  -1.010  -0.941
248   F         1.142   1.238   1.010   1.238   1.379   1.020   1.209   1.358   0.939
249   L        -0.128  -0.267  -0.352  -0.194  -0.379  -0.464  -0.114  -0.297  -0.408
250   E        -0.382  -0.330  -0.407  -0.469  -0.408  -0.514  -0.475  -0.425  -0.493
251   R        -1.014  -1.017  -0.918  -1.008  -1.014  -0.860  -0.956  -0.941  -0.817
252   F         0.188   0.172   0.106   0.091   0.046  -0.108   0.006  -0.029  -0.135
253   I        -0.459  -0.435  -0.434  -0.416  -0.362  -0.362  -0.595  -0.554  -0.529
254   E        -1.210  -1.148  -1.207  -1.033  -0.975  -1.072  -0.956  -0.897  -0.913
255   K        -1.329  -1.366  -1.252  -1.168  -1.240  -1.075  -1.076  -1.089  -0.953
256   F        -0.894  -0.710  -0.842  -0.698  -0.434  -0.624  -0.835  -0.647  -0.744
257   H        -1.329  -1.290  -1.244  -1.267  -1.245  -1.116  -1.076  -1.035  -0.947
258   P        -0.382  -0.398  -0.418  -0.215  -0.236  -0.304  -0.475  -0.480  -0.505
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   K        -0.436  -0.556  -0.511  -0.482  -0.682  -0.631  -0.515  -0.664  -0.606
261   Y        -0.499  -0.426  -0.445  -0.462  -0.346  -0.381  -0.619  -0.530  -0.537
262   E         0.087   0.117   0.093   0.050   0.100   0.059  -0.148  -0.101  -0.155
263   K        -0.860  -0.679  -0.843  -0.781  -0.480  -0.804  -0.777  -0.574  -0.736
264   I        -0.499  -0.486  -0.455  -0.392  -0.362  -0.312  -0.619  -0.601  -0.548
265   D         0.087   0.121   0.132  -0.020   0.054   0.048  -0.148  -0.075  -0.084
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   K        -1.210  -1.301  -1.254  -1.150  -1.304  -1.236  -0.956  -1.032  -0.954
268   N        -0.894  -0.938  -0.855  -0.867  -0.913  -0.826  -0.835  -0.859  -0.752
269   G        -1.210  -1.098  -1.172  -1.025  -0.855  -0.990  -0.956  -0.839  -0.881
270   Y        -0.894  -0.847  -0.869  -0.895  -0.817  -0.850  -0.835  -0.774  -0.767
271   E        -0.459  -0.373  -0.430  -0.560  -0.418  -0.490  -0.595  -0.494  -0.526
272   I         0.188   0.241   0.131   0.175   0.240   0.035   0.006   0.045  -0.097
273   V        -1.961  -1.914  -1.812  -1.501  -1.411  -1.290  -1.316  -1.271  -1.144
274   F        -0.894  -0.971  -0.876  -0.778  -0.865  -0.741  -0.835  -0.895  -0.778
275   F         0.623   0.647   0.720   0.455   0.497   0.585   0.247   0.276   0.358
276   E        -1.645  -1.596  -1.552  -1.407  -1.334  -1.291  -1.196  -1.150  -1.063
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   D        -0.894  -0.950  -0.879  -0.889  -0.983  -0.884  -0.835  -0.881  -0.781
280   Y         0.488   0.494   0.271   0.661   0.658   0.336   0.487   0.488   0.138
281   S        -0.382  -0.220  -0.375  -0.220   0.055  -0.199  -0.475  -0.252  -0.441
282   D        -1.329  -1.307  -1.254  -1.438  -1.412  -1.321  -1.076  -1.043  -0.954
283   L        -0.128  -0.213  -0.337  -0.211  -0.312  -0.473  -0.114  -0.227  -0.389
284   N         1.829   1.863   1.953   1.939   1.995   2.134   2.050   2.102   2.250
285   F         1.142   1.084   0.991   1.238   1.161   0.986   1.209   1.105   0.903
286   L         1.829   1.863   1.953   1.549   1.597   1.746   2.050   2.102   2.250
287   Q         0.488   0.326   0.226   0.776   0.566   0.413   0.487   0.242   0.068
288   L         1.829   1.863   1.953   1.549   1.597   1.746   2.050   2.102   2.250
289   L         1.829   1.863   1.953   1.549   1.597   1.746   2.050   2.102   2.250
290   L        -0.459  -0.431  -0.433  -0.726  -0.654  -0.643  -0.595  -0.556  -0.528
291   I         0.053  -0.005   0.069  -0.237  -0.318  -0.227  -0.234  -0.299  -0.200
292   T         0.623   0.639   0.712   0.471   0.471   0.569   0.247   0.260   0.340
293   C        -0.382  -0.498  -0.455  -0.244  -0.451  -0.421  -0.475  -0.602  -0.544
294   Q        -0.128  -0.213  -0.337   0.190   0.071  -0.117  -0.114  -0.227  -0.389
295   T        -0.459  -0.497  -0.462  -0.492  -0.538  -0.482  -0.595  -0.617  -0.556
296   K        -0.579  -0.516  -0.483  -0.732  -0.650  -0.575  -0.715  -0.645  -0.581
297   D        -0.894  -0.892  -0.853  -0.721  -0.709  -0.651  -0.835  -0.828  -0.756
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   K        -0.894  -0.854  -0.875  -0.820  -0.763  -0.776  -0.835  -0.794  -0.776
302   S        -1.329  -1.239  -1.231  -1.183  -1.055  -1.030  -1.076  -0.992  -0.938
303   Y        -0.579  -0.522  -0.502  -0.934  -0.845  -0.783  -0.715  -0.663  -0.603
304   F         1.142   1.050   0.983   1.286   1.176   1.068   1.209   1.047   0.888
305   L        -1.329  -1.335  -1.243  -1.308  -1.324  -1.175  -1.076  -1.065  -0.946
306   N        -0.894  -0.984  -0.918  -0.814  -0.947  -0.847  -0.835  -0.910  -0.815
307   L         1.829   1.863   1.953   1.549   1.597   1.746   2.050   2.102   2.250
308   K        -0.382  -0.453  -0.448  -0.375  -0.464  -0.437  -0.475  -0.553  -0.536
309   N        -0.894  -0.861  -0.876  -0.803  -0.758  -0.767  -0.835  -0.807  -0.777
310   H        -0.579  -0.548  -0.497  -0.519  -0.506  -0.402  -0.715  -0.675  -0.596
311   Y         1.829   1.863   1.953   1.897   1.955   2.093   2.050   2.102   2.250
312   L        -1.329  -1.297  -1.251  -1.394  -1.318  -1.278  -1.076  -1.036  -0.953
313   D        -1.645  -1.567  -1.526  -1.507  -1.403  -1.336  -1.196  -1.126  -1.045
314   F        -1.961  -1.914  -1.812  -1.776  -1.677  -1.564  -1.316  -1.271  -1.144
315   S        -0.382  -0.306  -0.403  -0.707  -0.579  -0.718  -0.475  -0.368  -0.479
316   Q        -1.329  -1.345  -1.238  -1.232  -1.259  -1.099  -1.076  -1.075  -0.943
317   A        -0.499  -0.504  -0.474  -0.599  -0.614  -0.563  -0.619  -0.630  -0.570
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   Y        -0.459  -0.410  -0.452  -0.406  -0.283  -0.403  -0.595  -0.523  -0.545
323   K        -1.014  -1.046  -0.924  -1.277  -1.308  -1.110  -0.956  -0.966  -0.822
324   S        -1.014  -0.942  -0.908  -1.053  -0.965  -0.872  -0.956  -0.884  -0.809
325   E        -0.144  -0.093  -0.006  -0.353  -0.297  -0.138  -0.475  -0.402  -0.292
326   L         0.804   0.833   0.831   0.458   0.501   0.490   0.608   0.649   0.588
327   E        -0.128  -0.064  -0.298   0.020   0.088  -0.252  -0.114  -0.041  -0.339
328   F        -0.579  -0.587  -0.502  -0.647  -0.644  -0.519  -0.715  -0.713  -0.602
329   L         0.623   0.606   0.702   0.158   0.141   0.295   0.247   0.189   0.319
330   G         0.488   0.326   0.226   0.657   0.418   0.247   0.487   0.242   0.068
331   Q        -0.894  -0.903  -0.904  -0.729  -0.763  -0.740  -0.835  -0.841  -0.803
332   E        -0.894  -0.939  -0.901  -0.865  -0.912  -0.875  -0.835  -0.872  -0.800
333   Y         1.829   1.863   1.953   1.897   1.955   2.093   2.050   2.102   2.250
334   F         1.829   1.863   1.953   1.902   1.958   2.097   2.050   2.102   2.250
335   N         0.804   0.886   0.814   0.801   0.932   0.790   0.608   0.748   0.554
336   I         0.488   0.516   0.262   0.655   0.704   0.285   0.487   0.527   0.124
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   V        -1.329  -1.309  -1.250  -1.099  -1.054  -0.974  -1.076  -1.050  -0.952
341   A        -1.014  -1.009  -0.911  -0.935  -0.909  -0.760  -0.956  -0.935  -0.811
342   P        -1.210  -1.227  -1.214  -0.904  -0.952  -0.963  -0.956  -0.964  -0.919
343   K        -0.894  -0.945  -0.907  -0.808  -0.857  -0.786  -0.835  -0.878  -0.806
344   Q         0.488   0.580   0.289   0.775   0.902   0.509   0.487   0.621   0.165
345   T        -1.329  -1.282  -1.232  -1.156  -1.081  -0.998  -1.076  -1.029  -0.939
346   N         1.829   1.863   1.953   1.939   1.995   2.134   2.050   2.102   2.250
347   F        -0.459  -0.536  -0.471  -0.295  -0.362  -0.264  -0.595  -0.657  -0.566
348   L         1.829   1.863   1.953   1.549   1.597   1.746   2.050   2.102   2.250
349   Q        -0.459  -0.478  -0.464  -0.598  -0.660  -0.643  -0.595  -0.595  -0.558
350   D         0.623   0.623   0.712   0.476   0.469   0.594   0.247   0.224   0.340
351   M         0.053   0.062   0.068  -0.080  -0.112  -0.100  -0.234  -0.228  -0.202
352   M         1.829   1.863   1.953   2.100   2.149   2.295   2.050   2.102   2.250
353   S         0.623   0.627   0.708   0.381   0.380   0.495   0.247   0.234   0.333
354   G         0.623   0.606   0.702   0.411   0.353   0.491   0.247   0.189   0.319
355   F         0.565   0.610   0.706   0.082   0.129   0.279   0.127   0.198   0.328
356   L         0.804   0.954   0.891   0.678   0.951   0.790   0.608   0.876   0.709
357   G         0.917   0.820   0.834   0.935   0.769   0.760   0.819   0.622   0.595
358   G         1.829   1.863   1.953   1.889   1.939   2.084   2.050   2.102   2.250
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
376   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   K         0.488   0.326   0.226   0.561   0.333   0.173   0.487   0.242   0.068
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12125
Output conservation file - output/Q12125
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
