1     M         1.661   1.689   1.816   1.783   1.831   2.027   1.822   1.863   2.079
2     S         0.928   0.884   0.715   0.980   0.943   0.736   0.978   0.906   0.583
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     A        -1.470  -1.436  -1.276  -1.347  -1.307  -1.076  -1.265  -1.225  -1.031
6     S        -0.824  -0.748  -0.771  -0.776  -0.675  -0.688  -0.856  -0.769  -0.758
7     K         0.332   0.348   0.485   0.103   0.118   0.322  -0.068  -0.052   0.137
8     E         0.230   0.228  -0.062   0.422   0.437   0.024   0.254   0.250  -0.175
9     E        -0.293  -0.335  -0.239  -0.371  -0.401  -0.238  -0.541  -0.579  -0.442
10    I        -0.362  -0.406  -0.281  -0.259  -0.345  -0.176  -0.590  -0.654  -0.493
11    A         0.928   0.811   0.718   0.663   0.522   0.440   0.978   0.788   0.588
12    A        -0.235  -0.215  -0.208  -0.645  -0.626  -0.535  -0.469  -0.436  -0.403
13    L        -1.373  -1.331  -1.239  -1.658  -1.654  -1.467  -1.193  -1.142  -1.001
14    I         0.928   1.020   0.740   1.238   1.355   1.008   0.978   1.115   0.629
15    V        -0.235  -0.249  -0.197  -0.022  -0.016   0.084  -0.469  -0.471  -0.391
16    N        -0.428  -0.295  -0.633  -0.123   0.046  -0.394  -0.349  -0.181  -0.588
17    Y         0.374   0.376   0.498   0.507   0.504   0.676   0.013   0.003   0.162
18    F         0.928   0.997   0.733   1.064   1.148   0.845   0.978   1.080   0.617
19    S        -0.699  -0.674  -0.738  -0.686  -0.622  -0.759  -0.710  -0.666  -0.719
20    S        -0.909  -0.869  -0.803  -0.796  -0.725  -0.659  -0.952  -0.905  -0.793
21    I        -0.584  -0.623  -0.723  -0.502  -0.596  -0.748  -0.541  -0.590  -0.696
22    V         0.112  -0.017  -0.116   0.460   0.288   0.115   0.089  -0.096  -0.255
23    E        -0.909  -0.876  -0.795  -1.125  -1.032  -0.946  -0.952  -0.918  -0.786
24    K        -1.246  -1.269  -1.208  -1.118  -1.128  -1.060  -1.072  -1.090  -0.974
25    K        -0.782  -0.676  -0.748  -0.911  -0.772  -0.854  -0.831  -0.718  -0.737
26    E        -0.909  -0.905  -0.805  -1.004  -0.994  -0.893  -0.952  -0.948  -0.797
27    I        -0.235  -0.236  -0.188  -0.091  -0.075  -0.011  -0.469  -0.450  -0.376
28    S        -1.710  -1.656  -1.577  -1.633  -1.544  -1.480  -1.313  -1.260  -1.126
29    E         0.928   0.884   0.715   0.961   0.908   0.591   0.978   0.906   0.583
30    D         0.928   0.811   0.718   1.041   0.896   0.749   0.978   0.788   0.588
31    G        -0.699  -0.771  -0.756  -0.446  -0.576  -0.600  -0.710  -0.794  -0.741
32    A        -1.246  -1.220  -1.202  -1.351  -1.293  -1.183  -1.072  -1.049  -0.969
33    D         0.312   0.337   0.484   0.051   0.092   0.310  -0.108  -0.074   0.136
34    S         0.928   0.884   0.715   0.949   0.905   0.664   0.978   0.906   0.583
35    L        -0.909  -0.893  -0.796  -0.777  -0.743  -0.587  -0.952  -0.919  -0.785
36    N        -0.782  -0.843  -0.776  -0.736  -0.819  -0.694  -0.831  -0.879  -0.765
37    V         0.928   0.884   0.715   1.227   1.187   0.960   0.978   0.906   0.583
38    A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
39    M        -0.428  -0.542  -0.680  -0.043  -0.239  -0.476  -0.349  -0.492  -0.644
40    D         0.230   0.061  -0.086   0.451   0.234   0.020   0.254   0.017  -0.210
41    C         1.661   1.689   1.816   2.013   2.057   2.254   1.822   1.863   2.079
42    I         0.928   0.937   0.728   1.214   1.232   0.935   0.978   0.989   0.607
43    S        -1.583  -1.628  -1.567  -1.686  -1.745  -1.610  -1.193  -1.227  -1.115
44    E         0.312   0.337   0.484   0.051   0.092   0.309  -0.108  -0.074   0.136
45    A        -0.091  -0.138  -0.177  -0.466  -0.550  -0.561  -0.228  -0.306  -0.357
46    F         1.661   1.689   1.816   1.903   1.947   2.146   1.822   1.863   2.079
47    G        -0.909  -0.886  -0.805  -1.005  -0.987  -0.849  -0.952  -0.932  -0.796
48    F        -0.362  -0.356  -0.258  -0.166  -0.162  -0.025  -0.590  -0.587  -0.462
49    E        -0.699  -0.774  -0.744  -0.641  -0.731  -0.716  -0.710  -0.775  -0.724
50    R        -0.909  -0.898  -0.809  -0.733  -0.718  -0.619  -0.952  -0.934  -0.799
51    E        -1.246  -1.233  -1.184  -1.169  -1.131  -1.091  -1.072  -1.043  -0.952
52    A        -0.699  -0.692  -0.735  -0.745  -0.743  -0.883  -0.710  -0.709  -0.719
53    V        -1.373  -1.368  -1.247  -1.128  -1.108  -0.915  -1.193  -1.176  -1.007
54    S        -0.699  -0.783  -0.735  -0.761  -0.887  -0.896  -0.710  -0.787  -0.718
55    G        -1.209  -1.171  -1.194  -1.300  -1.282  -1.359  -1.013  -0.971  -0.956
56    I        -0.824  -0.736  -0.756  -0.516  -0.387  -0.417  -0.856  -0.745  -0.737
57    L        -0.584  -0.585  -0.712  -0.275  -0.275  -0.424  -0.541  -0.544  -0.683
58    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    K        -0.307  -0.290  -0.241  -0.510  -0.485  -0.440  -0.536  -0.524  -0.443
60    S        -1.470  -1.450  -1.276  -1.693  -1.677  -1.419  -1.265  -1.237  -1.031
61    E        -1.739  -1.667  -1.589  -1.614  -1.520  -1.448  -1.328  -1.258  -1.133
62    F        -0.584  -0.718  -0.736  -0.189  -0.399  -0.483  -0.541  -0.706  -0.711
63    K        -1.583  -1.531  -1.550  -1.322  -1.282  -1.255  -1.193  -1.141  -1.101
64    G        -0.091  -0.105  -0.181  -0.225  -0.249  -0.393  -0.228  -0.251  -0.363
65    Q        -0.235  -0.312  -0.205  -0.246  -0.335  -0.172  -0.469  -0.552  -0.402
66    H        -2.047  -2.053  -1.911  -1.620  -1.600  -1.396  -1.434  -1.426  -1.246
67    L         1.661   1.689   1.816   1.661   1.700   1.906   1.822   1.863   2.079
68    A        -1.710  -1.675  -1.581  -1.780  -1.682  -1.566  -1.313  -1.275  -1.128
69    D        -0.909  -0.935  -0.805  -1.140  -1.199  -0.997  -0.952  -0.968  -0.797
70    I        -0.782  -0.817  -0.747  -0.673  -0.748  -0.608  -0.831  -0.854  -0.736
71    L        -0.091  -0.193  -0.196   0.061  -0.077  -0.043  -0.228  -0.378  -0.383
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    N        -1.739  -1.694  -1.590  -1.672  -1.563  -1.496  -1.328  -1.281  -1.133
81    S        -0.584  -0.595  -0.709  -0.534  -0.549  -0.754  -0.541  -0.556  -0.679
82    A        -0.824  -0.829  -0.774  -1.155  -1.150  -1.015  -0.856  -0.848  -0.758
83    S        -0.931  -0.899  -0.801  -1.081  -1.063  -0.907  -0.956  -0.916  -0.786
84    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    P        -0.931  -0.929  -0.809  -0.995  -0.994  -0.831  -0.956  -0.950  -0.795
87    E        -0.931  -0.923  -0.809  -1.123  -1.103  -0.891  -0.956  -0.944  -0.795
88    S        -1.036  -1.063  -1.140  -0.918  -0.954  -1.118  -0.831  -0.860  -0.902
89    N        -0.699  -0.684  -0.738  -0.746  -0.741  -0.824  -0.710  -0.709  -0.722
90    K        -1.373  -1.379  -1.240  -1.339  -1.336  -1.142  -1.193  -1.185  -1.002
91    K        -1.710  -1.726  -1.581  -1.618  -1.571  -1.432  -1.313  -1.313  -1.129
92    D        -1.246  -1.181  -1.193  -0.950  -0.853  -0.905  -1.072  -0.999  -0.958
93    D        -1.373  -1.398  -1.232  -1.479  -1.491  -1.291  -1.193  -1.197  -0.996
94    A        -1.036  -1.055  -1.149  -1.020  -1.045  -1.299  -0.831  -0.852  -0.911
95    E         0.928   0.884   0.715   1.005   0.962   0.695   0.978   0.906   0.583
96    N        -1.373  -1.301  -1.230  -1.511  -1.452  -1.299  -1.193  -1.125  -0.994
97    V        -0.235  -0.311  -0.212  -0.461  -0.593  -0.474  -0.469  -0.549  -0.409
98    E        -1.373  -1.379  -1.240  -1.431  -1.404  -1.215  -1.193  -1.185  -1.002
99    I        -0.699  -0.566  -0.716  -0.842  -0.691  -0.786  -0.710  -0.548  -0.693
100   N        -0.926  -0.929  -0.806  -0.859  -0.878  -0.725  -0.965  -0.958  -0.794
101   I        -0.909  -0.914  -0.812  -0.905  -0.921  -0.792  -0.952  -0.951  -0.804
102   P        -1.209  -1.219  -1.226  -1.060  -1.115  -1.239  -1.013  -1.021  -0.986
103   E        -0.824  -0.854  -0.779  -0.955  -1.006  -0.876  -0.856  -0.885  -0.767
104   D        -1.739  -1.726  -1.607  -1.750  -1.775  -1.600  -1.328  -1.308  -1.146
105   D         0.112  -0.013  -0.138   0.291   0.114  -0.080   0.089  -0.090  -0.286
106   A         0.863   0.778   0.675   0.558   0.439   0.312   0.877   0.734   0.508
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   E        -0.198  -0.091  -0.187  -0.444  -0.257  -0.479  -0.383  -0.234  -0.368
112   T        -1.036  -1.131  -1.173  -0.618  -0.777  -0.927  -0.831  -0.930  -0.935
113   K         1.661   1.689   1.816   1.653   1.705   1.898   1.822   1.863   2.079
114   A        -0.699  -0.766  -0.756  -0.969  -1.057  -0.974  -0.710  -0.785  -0.743
115   K        -0.091  -0.219  -0.194  -0.023  -0.197  -0.177  -0.228  -0.401  -0.378
116   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
117   E         0.374   0.432   0.518   0.168   0.273   0.374   0.013   0.111   0.204
118   D        -1.373  -1.347  -1.233  -1.658  -1.586  -1.453  -1.193  -1.157  -0.997
119   L         1.661   1.689   1.816   1.661   1.700   1.906   1.822   1.863   2.079
120   K         1.661   1.689   1.816   1.653   1.705   1.898   1.822   1.863   2.079
121   M        -1.036  -0.936  -1.130  -0.845  -0.705  -1.045  -0.831  -0.720  -0.893
122   Q        -0.235  -0.231  -0.186  -0.254  -0.231  -0.165  -0.469  -0.442  -0.374
123   G         1.661   1.689   1.816   1.544   1.586   1.789   1.822   1.863   2.079
124   N         1.661   1.689   1.816   1.687   1.721   1.932   1.822   1.863   2.079
125   K        -0.699  -0.774  -0.744  -0.616  -0.738  -0.736  -0.710  -0.775  -0.724
126   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
127   M         0.230   0.108  -0.073   0.557   0.407   0.134   0.254   0.081  -0.191
128   A         0.928   0.937   0.728   0.613   0.622   0.337   0.978   0.989   0.607
129   N        -1.373  -1.311  -1.232  -1.521  -1.467  -1.330  -1.193  -1.133  -0.996
130   K         0.928   0.937   0.728   1.057   1.085   0.832   0.978   0.989   0.607
131   D        -0.091   0.003  -0.143  -0.056   0.077  -0.151  -0.228  -0.100  -0.305
132   Y         0.312   0.341   0.487   0.395   0.439   0.655  -0.108  -0.067   0.140
133   E        -1.246  -1.233  -1.201  -1.048  -1.015  -0.979  -1.072  -1.056  -0.967
134   L        -0.699  -0.799  -0.745  -0.601  -0.722  -0.647  -0.710  -0.808  -0.726
135   A         0.928   0.937   0.728   0.613   0.622   0.337   0.978   0.989   0.607
136   I         0.928   0.811   0.718   1.214   1.066   0.917   0.978   0.788   0.588
137   N        -1.246  -1.099  -1.186  -1.375  -1.117  -1.302  -1.072  -0.918  -0.953
138   K        -0.091  -0.193  -0.196  -0.038  -0.190  -0.185  -0.228  -0.378  -0.383
139   Y         1.661   1.689   1.816   1.901   1.946   2.144   1.822   1.863   2.079
140   T         0.928   0.976   0.732   1.252   1.316   0.962   0.978   1.049   0.614
141   E        -0.699  -0.761  -0.755  -0.666  -0.750  -0.803  -0.710  -0.785  -0.740
142   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
143   I         0.928   0.884   0.715   1.214   1.164   0.912   0.978   0.906   0.583
144   K        -1.036  -0.997  -1.141  -0.784  -0.711  -0.960  -0.831  -0.785  -0.903
145   V        -0.444  -0.448  -0.293  -0.442  -0.444  -0.216  -0.710  -0.712  -0.510
146   L        -0.699  -0.662  -0.738  -0.643  -0.584  -0.722  -0.710  -0.658  -0.718
147   P         0.230   0.299  -0.042   0.489   0.578   0.002   0.254   0.349  -0.145
148   T        -0.699  -0.692  -0.728  -0.485  -0.456  -0.582  -0.710  -0.683  -0.709
149   N         0.928   0.811   0.718   1.043   0.883   0.737   0.978   0.788   0.588
150   A        -0.091  -0.119  -0.143  -0.357  -0.384  -0.373  -0.228  -0.245  -0.299
151   I         0.567   0.629   0.594   0.740   0.839   0.761   0.375   0.477   0.353
152   Y         1.661   1.689   1.816   1.901   1.946   2.144   1.822   1.863   2.079
153   Y         0.374   0.414   0.512   0.384   0.451   0.564   0.013   0.077   0.191
154   A         0.567   0.629   0.594   0.304   0.416   0.261   0.375   0.477   0.353
155   N         1.661   1.689   1.816   1.687   1.721   1.932   1.822   1.863   2.079
156   R         1.661   1.689   1.816   1.909   1.949   2.152   1.822   1.863   2.079
157   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
158   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
159   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
160   H         0.374   0.371   0.492   0.590   0.574   0.739   0.013  -0.007   0.151
161   S         0.928   0.811   0.718   0.949   0.809   0.668   0.978   0.788   0.588
162   S        -0.091  -0.193  -0.196  -0.167  -0.328  -0.376  -0.228  -0.378  -0.383
163   L        -0.091  -0.059  -0.145  -0.185  -0.128  -0.349  -0.228  -0.165  -0.302
164   K        -1.246  -1.290  -1.221  -1.057  -1.116  -1.018  -1.072  -1.103  -0.985
165   E        -1.036  -0.997  -1.141  -0.643  -0.590  -0.859  -0.831  -0.785  -0.903
166   Y        -0.235  -0.291  -0.211   0.115   0.066   0.185  -0.469  -0.517  -0.404
167   D         0.312   0.340   0.486   0.051   0.097   0.313  -0.108  -0.068   0.139
168   Q        -1.246  -1.187  -1.193  -1.072  -0.996  -1.019  -1.072  -1.003  -0.958
169   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
170   V         0.230   0.174  -0.081   0.645   0.588   0.249   0.254   0.176  -0.203
171   K        -0.909  -0.904  -0.804  -1.150  -1.175  -0.998  -0.952  -0.946  -0.795
172   D         1.661   1.689   1.816   1.675   1.719   1.920   1.822   1.863   2.079
173   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
174   E         0.230   0.108  -0.073   0.394   0.238  -0.048   0.254   0.081  -0.191
175   S        -1.246  -1.258  -1.210  -1.297  -1.335  -1.235  -1.072  -1.081  -0.975
176   A         0.928   0.811   0.718   0.683   0.550   0.485   0.978   0.788   0.588
177   I         0.230   0.061  -0.086   0.616   0.393   0.165   0.254   0.017  -0.210
178   S        -1.246  -1.251  -1.200  -1.259  -1.294  -1.225  -1.072  -1.074  -0.967
179   I        -0.444  -0.414  -0.287  -0.439  -0.399  -0.203  -0.710  -0.670  -0.503
180   D         0.928   1.020   0.740   1.047   1.164   0.799   0.978   1.115   0.629
181   P         1.661   1.689   1.816   1.827   1.867   2.070   1.822   1.863   2.079
182   S        -1.710  -1.690  -1.583  -1.530  -1.471  -1.351  -1.313  -1.287  -1.130
183   Y        -0.091  -0.119  -0.143   0.298   0.291   0.257  -0.228  -0.245  -0.299
184   F        -0.428  -0.542  -0.680  -0.272  -0.459  -0.643  -0.349  -0.492  -0.644
185   R         0.567   0.532   0.544   0.589   0.543   0.553   0.375   0.299   0.255
186   G        -0.235  -0.140  -0.187  -0.789  -0.666  -0.699  -0.469  -0.345  -0.371
187   Y        -0.091  -0.167  -0.182   0.304   0.205   0.201  -0.228  -0.337  -0.363
188   S         0.928   0.811   0.718   0.928   0.782   0.619   0.978   0.788   0.588
189   R         1.661   1.689   1.816   1.909   1.949   2.152   1.822   1.863   2.079
190   L         1.661   1.689   1.816   1.661   1.700   1.906   1.822   1.863   2.079
191   G         1.661   1.689   1.816   1.544   1.586   1.789   1.822   1.863   2.079
192   F        -0.235  -0.291  -0.211  -0.146  -0.202  -0.056  -0.469  -0.517  -0.404
193   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
194   K         0.928   0.884   0.715   1.057   1.022   0.812   0.978   0.906   0.583
195   Y         0.230   0.061  -0.086   0.681   0.460   0.237   0.254   0.017  -0.210
196   A         0.928   0.811   0.718   0.613   0.454   0.320   0.978   0.788   0.588
197   Q        -0.091  -0.050  -0.145  -0.029   0.031  -0.119  -0.228  -0.163  -0.303
198   G         0.567   0.638   0.591   0.410   0.515   0.421   0.375   0.491   0.347
199   K         0.374   0.434   0.522   0.180   0.287   0.391   0.013   0.114   0.210
200   P         0.374   0.434   0.522  -0.089  -0.019   0.144   0.013   0.114   0.210
201   E        -1.246  -1.273  -1.221  -1.262  -1.338  -1.278  -1.072  -1.091  -0.985
202   E        -0.444  -0.437  -0.288  -0.923  -0.939  -0.744  -0.710  -0.698  -0.503
203   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
204   L        -0.235  -0.301  -0.209  -0.350  -0.466  -0.352  -0.469  -0.534  -0.404
205   E        -0.091  -0.058  -0.162  -0.085  -0.052  -0.213  -0.228  -0.205  -0.334
206   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
207   Y         1.661   1.689   1.816   1.901   1.946   2.144   1.822   1.863   2.079
208   K        -0.091  -0.103  -0.174  -0.057  -0.048  -0.181  -0.228  -0.233  -0.349
209   K         0.928   0.937   0.728   1.039   1.067   0.790   0.978   0.989   0.607
210   V         0.374   0.434   0.522   0.162   0.254   0.384   0.013   0.114   0.210
211   L        -0.091  -0.123  -0.179   0.005  -0.032  -0.105  -0.228  -0.265  -0.358
212   D        -0.235  -0.215  -0.208  -0.345  -0.303  -0.291  -0.469  -0.436  -0.403
213   I        -1.246  -1.304  -1.217  -0.793  -0.846  -0.732  -1.072  -1.112  -0.981
214   E         0.928   0.811   0.718   1.019   0.881   0.733   0.978   0.788   0.588
215   G         0.928   0.811   0.718   0.936   0.798   0.685   0.978   0.788   0.588
216   D        -0.362  -0.359  -0.268  -0.473  -0.483  -0.363  -0.590  -0.594  -0.475
217   N        -0.824  -0.834  -0.775  -0.785  -0.821  -0.707  -0.856  -0.865  -0.763
218   A        -0.824  -0.875  -0.800  -1.188  -1.264  -1.109  -0.856  -0.895  -0.787
219   T        -0.235  -0.291  -0.211  -0.262  -0.330  -0.202  -0.469  -0.517  -0.404
220   E         0.374   0.359   0.487   0.178   0.138   0.315   0.013  -0.031   0.140
221   A        -0.091  -0.094  -0.167  -0.353  -0.367  -0.389  -0.228  -0.247  -0.342
222   M         0.928   0.811   0.718   1.151   1.008   0.857   0.978   0.788   0.588
223   K         0.230   0.380  -0.032   0.478   0.666   0.176   0.254   0.461  -0.131
224   R         0.374   0.414   0.512   0.386   0.456   0.566   0.013   0.077   0.191
225   D         0.374   0.434   0.522   0.075   0.172   0.291   0.013   0.114   0.210
226   Y        -0.091  -0.187  -0.179   0.237   0.102   0.089  -0.228  -0.350  -0.356
227   E         1.661   1.689   1.816   1.649   1.700   1.894   1.822   1.863   2.079
228   S         0.230   0.162  -0.061   0.563   0.440   0.040   0.254   0.152  -0.173
229   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
230   K         0.928   0.811   0.718   1.025   0.886   0.741   0.978   0.788   0.588
231   K         0.567   0.586   0.558   0.589   0.625   0.574   0.375   0.400   0.282
232   K        -0.235  -0.291  -0.211  -0.114  -0.160  -0.047  -0.469  -0.517  -0.404
233   V         0.928   0.811   0.718   1.201   1.058   0.904   0.978   0.788   0.588
234   E         0.230   0.108  -0.073   0.399   0.243  -0.039   0.254   0.081  -0.191
235   Q        -0.235  -0.183  -0.205  -0.204  -0.142  -0.106  -0.469  -0.416  -0.402
236   S        -0.782  -0.871  -0.777  -0.833  -0.921  -0.780  -0.831  -0.904  -0.766
237   L        -1.036  -1.131  -1.173  -0.892  -1.071  -1.200  -0.831  -0.930  -0.935
238   N        -1.246  -1.317  -1.230  -1.200  -1.323  -1.222  -1.072  -1.121  -0.991
239   L        -1.246  -1.272  -1.220  -1.188  -1.257  -1.210  -1.072  -1.090  -0.984
240   E        -0.782  -0.806  -0.771  -0.809  -0.827  -0.739  -0.831  -0.842  -0.760
241   K        -1.246  -1.317  -1.230  -1.093  -1.235  -1.098  -1.072  -1.121  -0.991
242   T        -1.246  -1.205  -1.196  -1.062  -1.002  -1.045  -1.072  -1.018  -0.963
243   V        -1.825  -1.797  -1.626  -1.707  -1.725  -1.432  -1.394  -1.360  -1.160
244   P        -0.926  -0.887  -0.801  -0.728  -0.672  -0.577  -0.965  -0.918  -0.790
245   E        -0.926  -0.873  -0.800  -1.368  -1.313  -1.177  -0.965  -0.905  -0.789
246   Q        -1.825  -1.797  -1.626  -1.674  -1.642  -1.401  -1.394  -1.360  -1.160
247   S        -0.307  -0.297  -0.239  -0.696  -0.698  -0.657  -0.536  -0.530  -0.441
248   R        -0.931  -0.896  -0.810  -1.158  -1.111  -1.000  -0.956  -0.912  -0.796
249   D        -0.391  -0.382  -0.267  -0.581  -0.567  -0.397  -0.648  -0.632  -0.477
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   A        -0.391  -0.363  -0.260  -0.765  -0.723  -0.605  -0.648  -0.611  -0.468
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   D        -1.246  -1.220  -1.191  -1.374  -1.327  -1.318  -1.072  -1.046  -0.959
260   V        -0.428  -0.432  -0.649  -0.548  -0.590  -0.805  -0.349  -0.361  -0.608
261   D        -0.782  -0.688  -0.748  -1.130  -1.049  -1.023  -0.831  -0.728  -0.737
262   A        -1.036  -1.131  -1.173  -1.172  -1.308  -1.333  -0.831  -0.930  -0.935
263   S         0.230   0.162  -0.061   0.301   0.220  -0.100   0.254   0.152  -0.173
264   Q        -0.428  -0.381  -0.653  -0.568  -0.529  -0.845  -0.349  -0.291  -0.612
265   G         0.230   0.061  -0.086   0.264   0.037  -0.220   0.254   0.017  -0.210
266   A        -0.091  -0.219  -0.194  -0.466  -0.643  -0.573  -0.228  -0.401  -0.378
267   S        -0.091  -0.131  -0.174  -0.301  -0.382  -0.519  -0.228  -0.294  -0.352
268   A         0.230   0.258  -0.050   0.008   0.041  -0.365   0.254   0.294  -0.157
269   G        -0.091  -0.010  -0.152  -0.363  -0.252  -0.538  -0.228  -0.125  -0.319
270   G         0.928   0.811   0.718   0.855   0.683   0.492   0.978   0.788   0.588
271   L        -1.246  -1.297  -1.208  -1.161  -1.280  -1.141  -1.072  -1.110  -0.973
272   P         0.928   0.976   0.732   1.229   1.291   0.999   0.978   1.049   0.614
273   D         1.661   1.689   1.816   1.675   1.719   1.920   1.822   1.863   2.079
274   L         0.230   0.339  -0.034   0.466   0.599   0.143   0.254   0.405  -0.133
275   G         0.374   0.369   0.491   0.033   0.011   0.175   0.013  -0.012   0.148
276   S         0.928   0.937   0.728   0.888   0.910   0.545   0.978   0.989   0.607
277   L        -0.699  -0.695  -0.722  -0.489  -0.479  -0.479  -0.710  -0.696  -0.704
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   L         0.312   0.346   0.489   0.227   0.294   0.504  -0.108  -0.056   0.144
282   G         0.928   0.976   0.732   0.899   0.967   0.623   0.978   1.049   0.614
283   G         1.661   1.689   1.816   1.544   1.586   1.789   1.822   1.863   2.079
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -         1.661   1.689   1.816   1.503   1.542   1.749   1.822   1.863   2.079
301   -         1.661   1.689   1.816   1.503   1.542   1.749   1.822   1.863   2.079
302   -         0.784   0.791   0.666   0.707   0.720   0.523   0.750   0.755   0.491
303   -         0.784   0.791   0.666   0.939   0.954   0.719   0.750   0.755   0.491
304   -         0.784   0.791   0.666   0.978   0.985   0.757   0.750   0.755   0.491
305   G        -0.782  -0.669  -0.754  -0.894  -0.731  -0.830  -0.831  -0.712  -0.741
306   L         0.567   0.586   0.558   0.595   0.619   0.578   0.375   0.400   0.282
307   G        -0.091  -0.025  -0.150  -0.363  -0.256  -0.529  -0.228  -0.134  -0.315
308   G        -1.246  -1.149  -1.196  -1.432  -1.300  -1.405  -1.072  -0.990  -0.963
309   L        -0.091  -0.059  -0.145   0.005   0.067  -0.048  -0.228  -0.165  -0.302
310   M         0.928   1.011   0.737   1.151   1.264   0.889   0.978   1.101   0.623
311   N         1.661   1.689   1.816   1.687   1.721   1.932   1.822   1.863   2.079
312   N         1.661   1.689   1.816   1.687   1.721   1.932   1.822   1.863   2.079
313   P         1.661   1.689   1.816   1.827   1.867   2.070   1.822   1.863   2.079
314   Q        -0.091  -0.193  -0.196  -0.038  -0.252  -0.306  -0.228  -0.378  -0.383
315   L        -0.909  -0.879  -0.790  -0.690  -0.618  -0.507  -0.952  -0.900  -0.779
316   M         0.567   0.543   0.547   0.511   0.452   0.338   0.375   0.321   0.260
317   Q         0.928   0.811   0.718   1.200   1.050   0.909   0.978   0.788   0.588
318   A         0.374   0.351   0.487  -0.115  -0.136   0.098   0.013  -0.047   0.141
319   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
320   Q         0.230   0.175  -0.061   0.610   0.544   0.212   0.254   0.169  -0.173
321   K        -1.246  -1.169  -1.194  -1.131  -1.037  -1.058  -1.072  -1.007  -0.962
322   M        -0.235  -0.239  -0.206  -0.196  -0.215  -0.123  -0.469  -0.477  -0.404
323   M         1.661   1.689   1.816   1.783   1.831   2.027   1.822   1.863   2.079
324   S         0.567   0.538   0.547   0.489   0.450   0.449   0.375   0.311   0.260
325   N        -0.091  -0.161  -0.169  -0.063  -0.168  -0.216  -0.228  -0.310  -0.342
326   P         1.661   1.689   1.816   1.837   1.881   2.080   1.822   1.863   2.079
327   G        -1.246  -1.201  -1.199  -1.305  -1.238  -1.257  -1.072  -1.020  -0.965
328   A         0.230   0.241  -0.059   0.021   0.032  -0.351   0.254   0.267  -0.170
329   M         0.374   0.365   0.490   0.280   0.245   0.415   0.013  -0.019   0.147
330   Q        -0.091  -0.193  -0.196   0.076  -0.106  -0.145  -0.228  -0.378  -0.383
331   N         0.230   0.327  -0.040   0.461   0.578   0.098   0.254   0.389  -0.142
332   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   M        -0.235  -0.291  -0.211  -0.233  -0.285  -0.151  -0.469  -0.517  -0.404
336   M         0.928   1.023   0.739   1.186   1.308   0.970   0.978   1.119   0.628
337   Q        -0.362  -0.381  -0.263  -0.478  -0.520  -0.340  -0.590  -0.622  -0.470
338   D         0.374   0.376   0.498   0.202   0.186   0.366   0.013   0.003   0.162
339   P         1.661   1.689   1.816   1.827   1.867   2.070   1.822   1.863   2.079
340   S        -0.699  -0.799  -0.745  -0.994  -1.116  -0.988  -0.710  -0.808  -0.726
341   I        -0.699  -0.668  -0.728  -0.373  -0.328  -0.422  -0.710  -0.667  -0.710
342   R        -0.362  -0.346  -0.260  -0.441  -0.468  -0.386  -0.590  -0.573  -0.465
343   Q        -0.091  -0.193  -0.196   0.089  -0.090  -0.121  -0.228  -0.378  -0.383
344   M         1.661   1.689   1.816   1.783   1.831   2.027   1.822   1.863   2.079
345   A         1.661   1.689   1.816   1.260   1.294   1.509   1.822   1.863   2.079
346   E        -1.373  -1.371  -1.236  -1.171  -1.152  -0.955  -1.193  -1.179  -0.999
347   G        -0.699  -0.729  -0.730  -0.400  -0.450  -0.468  -0.710  -0.736  -0.712
348   F         0.567   0.620   0.568   0.787   0.871   0.746   0.375   0.461   0.301
349   A        -1.246  -1.114  -1.189  -1.145  -0.904  -1.097  -1.072  -0.928  -0.953
350   S        -0.198  -0.139  -0.207  -0.393  -0.314  -0.431  -0.383  -0.314  -0.397
351   G         1.661   1.689   1.816   1.544   1.586   1.789   1.822   1.863   2.079
352   G         0.928   0.976   0.732   0.915   0.980   0.659   0.978   1.049   0.614
353   G         0.230   0.302  -0.043   0.289   0.384  -0.097   0.254   0.353  -0.146
354   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   T        -0.909  -0.878  -0.783  -0.818  -0.750  -0.631  -0.952  -0.900  -0.769
358   P         1.661   1.689   1.816   1.827   1.867   2.070   1.822   1.863   2.079
359   N        -0.091  -0.050  -0.145  -0.070  -0.005  -0.175  -0.228  -0.163  -0.303
360   L         0.374   0.382   0.490   0.237   0.242   0.402   0.013   0.014   0.148
361   S         0.928   0.976   0.732   0.947   1.020   0.687   0.978   1.049   0.614
362   D        -1.373  -1.319  -1.239  -1.339  -1.279  -1.136  -1.193  -1.134  -1.001
363   L        -0.091   0.009  -0.147   0.005   0.133  -0.059  -0.228  -0.095  -0.312
364   M         0.928   0.811   0.718   1.098   0.932   0.730   0.978   0.788   0.588
365   N         0.928   0.976   0.732   1.043   1.102   0.762   0.978   1.049   0.614
366   N         0.374   0.389   0.493   0.202   0.211   0.355   0.013   0.029   0.152
367   P         1.661   1.689   1.816   1.827   1.867   2.070   1.822   1.863   2.079
368   A        -1.246  -1.276  -1.207  -1.398  -1.432  -1.301  -1.072  -1.086  -0.970
369   L        -0.091  -0.018  -0.161   0.040   0.121  -0.028  -0.228  -0.141  -0.333
370   R        -0.699  -0.707  -0.745  -0.421  -0.473  -0.568  -0.710  -0.726  -0.731
371   N        -0.198  -0.182  -0.194  -0.223  -0.205  -0.239  -0.383  -0.359  -0.380
372   M         0.332   0.340   0.485   0.192   0.186   0.400  -0.068  -0.068   0.136
373   A         1.661   1.689   1.816   1.251   1.286   1.499   1.822   1.863   2.079
374   G        -0.969  -0.913  -0.813  -1.033  -0.921  -0.800  -1.013  -0.952  -0.804
375   N        -0.909  -0.875  -0.794  -0.912  -0.874  -0.762  -0.952  -0.905  -0.784
376   L        -0.091   0.007  -0.157   0.195   0.342   0.072  -0.228  -0.089  -0.321
377   F        -0.235  -0.203  -0.198  -0.122  -0.068  -0.072  -0.469  -0.415  -0.386
378   G         0.928   0.811   0.718   0.915   0.768   0.636   0.978   0.788   0.588
379   G         0.230   0.108  -0.073   0.224   0.052  -0.284   0.254   0.081  -0.191
380   A        -0.307  -0.320  -0.226  -0.791  -0.796  -0.672  -0.536  -0.543  -0.420
381   G         0.423   0.426   0.517   0.149   0.144   0.269   0.107   0.101   0.201
382   A         0.352   0.363   0.495  -0.238  -0.232  -0.011  -0.030  -0.024   0.156
383   Q        -0.931  -0.832  -0.795  -0.935  -0.804  -0.734  -0.956  -0.837  -0.779
384   S        -0.391  -0.334  -0.250  -0.674  -0.596  -0.471  -0.648  -0.578  -0.455
385   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   E         0.352   0.350   0.488   0.068   0.047   0.260  -0.030  -0.049   0.143
394   T        -0.188  -0.108  -0.206  -0.078   0.017  -0.093  -0.339  -0.225  -0.386
395   P        -1.354  -1.284  -1.225  -1.448  -1.357  -1.239  -1.171  -1.102  -0.988
396   D         0.928   0.997   0.733   0.913   1.004   0.658   0.978   1.080   0.617
397   N        -0.909  -0.860  -0.797  -1.011  -0.952  -0.859  -0.952  -0.894  -0.786
398   E        -1.710  -1.679  -1.584  -1.837  -1.796  -1.607  -1.313  -1.278  -1.130
399   N        -1.373  -1.321  -1.232  -1.368  -1.291  -1.155  -1.193  -1.140  -0.996
400   K        -1.354  -1.322  -1.230  -1.290  -1.242  -1.088  -1.171  -1.134  -0.992
401   Q        -1.036  -0.951  -1.135  -0.582  -0.458  -0.757  -0.831  -0.736  -0.897
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12118
Output conservation file - output/Q12118
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
