1     M         1.874   1.951   1.995   2.044   2.181   2.244   2.094   2.196   2.279
2     S        -0.275  -0.438  -0.408  -0.268  -0.546  -0.493  -0.332  -0.539  -0.502
3     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     F         0.434   0.528   0.468   0.271   0.425   0.324   0.169   0.320   0.186
5     E         0.434   0.477   0.460   0.377   0.454   0.440   0.169   0.226   0.171
6     T         0.434   0.477   0.460   0.440   0.505   0.435   0.169   0.226   0.171
7     L         1.874   1.951   1.995   1.823   1.941   2.024   2.094   2.196   2.279
8     I        -0.512  -0.505  -0.419  -0.757  -0.760  -0.625  -0.678  -0.632  -0.521
9     K         0.742   0.664   0.624   0.832   0.722   0.629   0.708   0.560   0.476
10    R         0.352   0.374   0.437   0.203   0.151   0.273   0.015   0.033   0.126
11    G        -0.275  -0.438  -0.408  -0.238  -0.472  -0.448  -0.332  -0.539  -0.502
12    G        -0.275  -0.438  -0.408  -0.201  -0.430  -0.391  -0.332  -0.539  -0.502
13    N         0.742   0.643   0.625   0.930   0.775   0.744   0.708   0.524   0.477
14    E        -0.275  -0.438  -0.408   0.056  -0.195  -0.169  -0.332  -0.539  -0.502
15    A        -0.275  -0.438  -0.408  -0.407  -0.639  -0.583  -0.332  -0.539  -0.502
16    I        -0.275  -0.247  -0.331  -0.421  -0.407  -0.532  -0.332  -0.287  -0.396
17    K        -0.275  -0.438  -0.408  -0.151  -0.412  -0.381  -0.332  -0.539  -0.502
18    I        -0.275  -0.438  -0.408  -0.362  -0.589  -0.566  -0.332  -0.539  -0.502
19    N        -0.275  -0.438  -0.408   0.060  -0.151  -0.102  -0.332  -0.539  -0.502
20    P         0.742   0.643   0.625   0.808   0.658   0.607   0.708   0.524   0.477
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    P         1.874   1.951   1.995   1.929   2.069   2.130   2.094   2.196   2.279
23    T        -0.275  -0.438  -0.408  -0.057  -0.237  -0.201  -0.332  -0.539  -0.502
24    G         0.742   0.643   0.625   0.740   0.599   0.550   0.708   0.524   0.477
25    A         0.742   0.664   0.624   0.638   0.542   0.509   0.708   0.560   0.476
26    D         0.602   0.460   0.505   0.731   0.441   0.511   0.470   0.195   0.257
27    F         0.602   0.460   0.505   0.579   0.377   0.457   0.470   0.195   0.257
28    H         0.742   0.643   0.625   1.043   0.909   0.868   0.708   0.524   0.477
29    I         0.742   0.664   0.624   0.618   0.504   0.423   0.708   0.560   0.476
30    T         0.352   0.374   0.437   0.145   0.166   0.265   0.015   0.033   0.126
31    S         0.602   0.461   0.505   0.564   0.295   0.370   0.470   0.197   0.257
32    R         0.602   0.461   0.505   0.808   0.583   0.663   0.470   0.197   0.257
33    G         1.874   1.951   1.995   1.819   1.949   2.021   2.094   2.196   2.279
34    S         1.874   1.951   1.995   1.848   1.952   2.049   2.094   2.196   2.279
35    D         0.742   0.643   0.625   1.017   0.890   0.854   0.708   0.524   0.477
36    W         0.742   0.643   0.625   0.971   0.826   0.798   0.708   0.524   0.477
37    F        -1.139  -1.024  -1.049  -1.329  -1.143  -1.181  -1.025  -0.869  -0.875
38    W         1.874   1.951   1.995   2.040   2.157   2.240   2.094   2.196   2.279
39    T         0.742   0.915   0.684   0.583   0.833   0.516   0.708   0.977   0.583
40    C        -0.512  -0.396  -0.409  -0.779  -0.631  -0.590  -0.678  -0.516  -0.514
41    F         0.742   0.664   0.624   0.719   0.619   0.549   0.708   0.560   0.476
42    C         0.352   0.374   0.437   0.219   0.173   0.270   0.015   0.033   0.126
43    C        -0.275  -0.247  -0.331  -0.302  -0.304  -0.373  -0.332  -0.287  -0.396
44    Y        -0.275   0.002  -0.259  -0.222   0.184  -0.173  -0.332   0.067  -0.296
45    L        -0.275  -0.208  -0.321  -0.469  -0.416  -0.559  -0.332  -0.238  -0.382
46    L         0.352   0.411   0.445  -0.038   0.032   0.110   0.015   0.104   0.143
47    F        -1.139  -1.024  -1.044  -0.948  -0.729  -0.806  -1.025  -0.867  -0.870
48    G        -0.275  -0.247  -0.331  -0.431  -0.377  -0.503  -0.332  -0.287  -0.396
49    L         0.352   0.400   0.441  -0.066   0.003   0.066   0.015   0.084   0.136
50    I         0.742   0.915   0.684   0.652   0.904   0.565   0.708   0.977   0.583
51    L        -0.512  -0.367  -0.409  -0.737  -0.557  -0.553  -0.678  -0.486  -0.514
52    T        -1.139  -1.153  -1.105  -1.190  -1.187  -1.119  -1.025  -1.003  -0.935
53    F        -0.275  -0.247  -0.331  -0.469  -0.475  -0.577  -0.332  -0.287  -0.396
54    L         0.742   0.643   0.625   0.609   0.424   0.425   0.708   0.524   0.477
55    M        -0.275  -0.438  -0.408  -0.048  -0.297  -0.280  -0.332  -0.539  -0.502
56    F         0.742   0.643   0.625   0.680   0.530   0.488   0.708   0.524   0.477
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    R        -0.275  -0.438  -0.408   0.029  -0.193  -0.163  -0.332  -0.539  -0.502
62    K         0.742   0.664   0.624   0.818   0.710   0.606   0.708   0.560   0.476
63    P        -1.139  -1.132  -1.098  -0.963  -0.918  -0.886  -1.025  -0.984  -0.927
64    V        -1.139  -1.132  -1.098  -1.197  -1.133  -1.117  -1.025  -0.984  -0.927
65    N        -0.275  -0.438  -0.408  -0.073  -0.331  -0.304  -0.332  -0.539  -0.502
66    D        -1.139  -1.139  -1.102  -0.700  -0.668  -0.618  -1.025  -0.991  -0.932
67    R         1.874   1.951   1.995   2.044   2.164   2.244   2.094   2.196   2.279
68    F         0.352   0.411   0.445  -0.015   0.061   0.121   0.015   0.104   0.143
69    F        -1.139  -0.994  -1.044  -1.229  -0.965  -1.074  -1.025  -0.836  -0.869
70    Y        -0.275  -0.438  -0.408  -0.094  -0.339  -0.286  -0.332  -0.539  -0.502
71    L        -0.512  -0.513  -0.423  -0.743  -0.732  -0.576  -0.678  -0.643  -0.527
72    T        -0.275  -0.438  -0.408  -0.298  -0.584  -0.569  -0.332  -0.539  -0.502
73    G        -0.478  -0.477  -0.454  -0.699  -0.659  -0.627  -0.613  -0.602  -0.565
74    I         1.874   1.951   1.995   1.729   1.867   1.931   2.094   2.196   2.279
75    A         0.602   0.461   0.505   0.333   0.064   0.160   0.470   0.197   0.257
76    P         0.602   0.461   0.505   0.594   0.356   0.406   0.470   0.197   0.257
77    N        -0.275  -0.224  -0.317  -0.025   0.023  -0.080  -0.332  -0.263  -0.376
78    F        -0.512  -0.342  -0.413  -0.852  -0.604  -0.679  -0.678  -0.431  -0.513
79    F         0.352   0.374   0.437   0.013   0.018   0.134   0.015   0.033   0.126
80    M        -0.275  -0.438  -0.408  -0.136  -0.436  -0.417  -0.332  -0.539  -0.502
81    C        -1.139  -0.994  -1.044  -1.001  -0.721  -0.861  -1.025  -0.836  -0.869
82    I        -0.275  -0.438  -0.408  -0.430  -0.708  -0.671  -0.332  -0.539  -0.502
83    A         1.874   1.951   1.995   1.658   1.767   1.860   2.094   2.196   2.279
84    Y         1.874   1.951   1.995   1.941   2.059   2.142   2.094   2.196   2.279
85    F         1.874   1.951   1.995   1.795   1.914   1.996   2.094   2.196   2.279
86    T        -0.275  -0.221  -0.325  -0.281  -0.205  -0.383  -0.332  -0.254  -0.387
87    M         0.352   0.530   0.533   0.214   0.583   0.542   0.015   0.324   0.308
88    A         1.874   1.951   1.995   1.658   1.767   1.860   2.094   2.196   2.279
89    S        -0.275  -0.438  -0.408  -0.242  -0.502  -0.453  -0.332  -0.539  -0.502
90    N         1.874   1.951   1.995   2.020   2.140   2.221   2.094   2.196   2.279
91    L         0.742   0.643   0.625   0.654   0.490   0.497   0.708   0.524   0.477
92    G         0.742   0.664   0.624   0.714   0.602   0.506   0.708   0.560   0.476
93    W         0.742   0.643   0.625   0.918   0.743   0.712   0.708   0.524   0.477
94    I         0.602   0.460   0.505   0.436   0.227   0.282   0.470   0.195   0.257
95    P        -0.275  -0.438  -0.408  -0.066  -0.264  -0.236  -0.332  -0.539  -0.502
96    V         1.874   1.951   1.995   1.766   1.871   1.968   2.094   2.196   2.279
97    K        -1.139  -1.153  -1.105  -1.001  -1.073  -0.979  -1.025  -1.003  -0.935
98    A         0.352   0.374   0.437  -0.058  -0.026   0.101   0.015   0.033   0.126
99    K        -0.275  -0.438  -0.408  -0.085  -0.311  -0.281  -0.332  -0.539  -0.502
100   Y        -0.275  -0.438  -0.408  -0.172  -0.450  -0.406  -0.332  -0.539  -0.502
101   N         0.742   0.643   0.625   0.930   0.775   0.744   0.708   0.524   0.477
102   H        -0.275  -0.438  -0.408   0.044  -0.217  -0.182  -0.332  -0.539  -0.502
103   V         0.742   0.643   0.625   0.666   0.502   0.484   0.708   0.524   0.477
104   Q         0.742   0.915   0.684   1.014   1.264   0.956   0.708   0.977   0.583
105   T         1.874   1.951   1.995   1.816   1.937   2.018   2.094   2.196   2.279
106   S         1.874   1.951   1.995   1.887   2.007   2.088   2.094   2.196   2.279
107   T         1.874   1.951   1.995   1.816   1.937   2.018   2.094   2.196   2.279
108   Q         1.874   1.951   1.995   2.109   2.231   2.309   2.094   2.196   2.279
109   K         0.434   0.477   0.460   0.514   0.579   0.514   0.169   0.226   0.171
110   E         0.602   0.748   0.572   0.888   1.115   0.853   0.470   0.704   0.380
111   H         0.742   0.643   0.625   1.082   0.955   0.931   0.708   0.524   0.477
112   P        -0.275  -0.438  -0.408  -0.213  -0.474  -0.461  -0.332  -0.539  -0.502
113   G        -0.275  -0.438  -0.408  -0.238  -0.472  -0.448  -0.332  -0.539  -0.502
114   Y        -0.275  -0.247  -0.331  -0.298  -0.259  -0.368  -0.332  -0.287  -0.396
115   R         1.874   1.951   1.995   2.044   2.164   2.244   2.094   2.196   2.279
116   Q         0.742   0.643   0.625   1.057   0.931   0.895   0.708   0.524   0.477
117   I         0.742   0.643   0.625   0.630   0.490   0.445   0.708   0.524   0.477
118   F         0.742   0.643   0.625   0.731   0.594   0.570   0.708   0.524   0.477
119   Y         0.742   0.664   0.624   0.899   0.798   0.744   0.708   0.560   0.476
120   S        -0.275  -0.263  -0.335  -0.474  -0.485  -0.565  -0.332  -0.311  -0.401
121   R         0.742   0.664   0.624   0.978   0.879   0.805   0.708   0.560   0.476
122   F         0.742   0.915   0.684   0.839   1.099   0.753   0.708   0.977   0.583
123   V         0.742   0.643   0.625   0.652   0.488   0.461   0.708   0.524   0.477
124   G        -0.275  -0.438  -0.408  -0.223  -0.460  -0.424  -0.332  -0.539  -0.502
125   W         1.874   1.951   1.995   2.040   2.157   2.240   2.094   2.196   2.279
126   F        -0.275  -0.438  -0.408  -0.383  -0.692  -0.637  -0.332  -0.539  -0.502
127   L        -1.139  -1.153  -1.105  -1.120  -1.190  -1.126  -1.025  -1.003  -0.935
128   A        -0.275  -0.438  -0.408  -0.388  -0.622  -0.555  -0.332  -0.539  -0.502
129   L         0.352   0.374   0.437  -0.038  -0.027   0.100   0.015   0.033   0.126
130   P         1.874   1.951   1.995   1.929   2.069   2.130   2.094   2.196   2.279
131   W        -0.275  -0.438  -0.408  -0.180  -0.522  -0.483  -0.332  -0.539  -0.502
132   P        -0.275  -0.438  -0.408  -0.281  -0.569  -0.567  -0.332  -0.539  -0.502
133   I        -0.275   0.031  -0.250  -0.440   0.054  -0.403  -0.332   0.108  -0.283
134   I        -0.275  -0.438  -0.408  -0.440  -0.727  -0.686  -0.332  -0.539  -0.502
135   Q        -0.275  -0.438  -0.408  -0.021  -0.297  -0.276  -0.332  -0.539  -0.502
136   I        -1.139  -1.153  -1.105  -1.333  -1.322  -1.254  -1.025  -1.003  -0.935
137   C        -1.139  -1.153  -1.105  -0.941  -0.931  -0.845  -1.025  -1.003  -0.935
138   M        -1.139  -1.024  -1.049  -1.134  -0.923  -0.974  -1.025  -0.869  -0.875
139   L        -0.275  -0.224  -0.317  -0.311  -0.261  -0.345  -0.332  -0.263  -0.376
140   A        -1.139  -1.153  -1.105  -1.268  -1.302  -1.241  -1.025  -1.003  -0.935
141   G         0.352   0.530   0.533   0.167   0.497   0.470   0.015   0.324   0.308
142   T         0.352   0.374   0.437   0.099   0.105   0.203   0.015   0.033   0.126
143   P         0.352   0.374   0.437   0.176   0.190   0.290   0.015   0.033   0.126
144   F        -1.139  -1.024  -1.044  -1.220  -0.998  -1.060  -1.025  -0.867  -0.870
145   W        -0.275  -0.438  -0.408  -0.180  -0.522  -0.483  -0.332  -0.539  -0.502
146   Q        -1.139  -1.139  -1.102  -0.721  -0.717  -0.652  -1.025  -0.991  -0.932
147   M        -0.275  -0.013  -0.252  -0.332   0.084  -0.281  -0.332   0.047  -0.287
148   A         0.742   0.664   0.624   0.551   0.420   0.368   0.708   0.560   0.476
149   F         0.742   0.643   0.625   0.731   0.594   0.570   0.708   0.524   0.477
150   N         0.742   0.643   0.625   0.910   0.748   0.713   0.708   0.524   0.477
151   V        -0.512  -0.376  -0.409  -0.723  -0.533  -0.535  -0.678  -0.495  -0.514
152   C        -1.139  -0.994  -1.044  -1.022  -0.761  -0.884  -1.025  -0.836  -0.869
153   I        -1.139  -1.153  -1.105  -1.049  -1.095  -1.037  -1.025  -1.003  -0.935
154   T        -1.139  -1.139  -1.102  -1.149  -1.164  -1.104  -1.025  -0.991  -0.932
155   E        -1.139  -1.139  -1.102  -0.807  -0.866  -0.760  -1.025  -0.991  -0.932
156   F        -0.512  -0.495  -0.418  -0.816  -0.771  -0.649  -0.678  -0.620  -0.519
157   F        -0.275  -0.438  -0.408  -0.312  -0.577  -0.526  -0.332  -0.539  -0.502
158   T        -1.139  -1.139  -1.102  -1.196  -1.220  -1.161  -1.025  -0.991  -0.932
159   V         0.742   0.664   0.624   0.652   0.524   0.459   0.708   0.560   0.476
160   C         0.742   0.664   0.624   1.007   0.909   0.816   0.708   0.560   0.476
161   W        -1.139  -1.153  -1.105  -1.130  -1.181  -1.056  -1.025  -1.003  -0.935
162   L         1.874   1.951   1.995   1.716   1.806   1.918   2.094   2.196   2.279
163   I        -0.275  -0.438  -0.408  -0.459  -0.746  -0.716  -0.332  -0.539  -0.502
164   A         1.874   1.951   1.995   1.658   1.767   1.860   2.094   2.196   2.279
165   A         1.874   1.951   1.995   1.658   1.767   1.860   2.094   2.196   2.279
166   C        -0.275  -0.438  -0.408  -0.039  -0.333  -0.302  -0.332  -0.539  -0.502
167   V         0.742   0.643   0.625   0.691   0.544   0.523   0.708   0.524   0.477
168   H        -0.275  -0.438  -0.408   0.007  -0.267  -0.239  -0.332  -0.539  -0.502
169   S         1.874   1.951   1.995   1.848   1.952   2.049   2.094   2.196   2.279
170   T        -0.275  -0.438  -0.408  -0.142  -0.348  -0.329  -0.332  -0.539  -0.502
171   Y         1.874   1.951   1.995   1.941   2.059   2.142   2.094   2.196   2.279
172   K         1.874   1.951   1.995   1.953   2.096   2.153   2.094   2.196   2.279
173   W         1.874   1.951   1.995   2.040   2.157   2.240   2.094   2.196   2.279
174   G         0.742   0.643   0.625   0.714   0.565   0.507   0.708   0.524   0.477
175   Y         0.742   0.664   0.624   0.820   0.685   0.617   0.708   0.560   0.476
176   Y        -0.512  -0.366  -0.409  -0.578  -0.370  -0.396  -0.678  -0.485  -0.514
177   T        -0.275  -0.438  -0.408  -0.281  -0.548  -0.543  -0.332  -0.539  -0.502
178   I         0.352   0.374   0.437  -0.020   0.022   0.115   0.015   0.033   0.126
179   G        -0.275  -0.438  -0.408  -0.324  -0.606  -0.580  -0.332  -0.539  -0.502
180   L        -1.139  -1.153  -1.105  -1.093  -1.187  -1.112  -1.025  -1.003  -0.935
181   G        -0.275  -0.438  -0.408  -0.332  -0.627  -0.592  -0.332  -0.539  -0.502
182   A         0.352   0.404   0.444  -0.058   0.031   0.097   0.015   0.090   0.141
183   A        -1.139  -1.139  -1.102  -1.158  -1.088  -1.043  -1.025  -0.991  -0.932
184   I         0.742   0.643   0.625   0.637   0.505   0.456   0.708   0.524   0.477
185   V        -0.275  -0.438  -0.408  -0.395  -0.678  -0.636  -0.332  -0.539  -0.502
186   V        -1.139  -1.024  -1.044  -1.410  -1.273  -1.255  -1.025  -0.867  -0.870
187   S        -1.766  -1.652  -1.629  -1.855  -1.742  -1.632  -1.371  -1.220  -1.172
188   I        -0.275  -0.438  -0.408  -0.449  -0.726  -0.701  -0.332  -0.539  -0.502
189   S        -0.275  -0.438  -0.408  -0.095  -0.300  -0.231  -0.332  -0.539  -0.502
190   V        -1.139  -1.139  -1.102  -1.259  -1.253  -1.197  -1.025  -0.991  -0.932
191   M        -0.275  -0.438  -0.408  -0.144  -0.456  -0.429  -0.332  -0.539  -0.502
192   T        -0.275  -0.438  -0.408  -0.264  -0.536  -0.516  -0.332  -0.539  -0.502
193   T        -0.275  -0.438  -0.408  -0.200  -0.454  -0.418  -0.332  -0.539  -0.502
194   S        -1.139  -1.153  -1.105  -1.082  -1.090  -1.028  -1.025  -1.003  -0.935
195   Y        -0.512  -0.513  -0.423  -0.439  -0.402  -0.274  -0.678  -0.643  -0.527
196   N        -1.766  -1.652  -1.629  -1.434  -1.269  -1.214  -1.371  -1.220  -1.172
197   L        -0.275  -0.438  -0.408  -0.359  -0.628  -0.548  -0.332  -0.539  -0.502
198   V        -0.512  -0.328  -0.414  -0.917  -0.635  -0.755  -0.678  -0.419  -0.515
199   K        -1.139  -1.132  -1.098  -0.917  -0.907  -0.838  -1.025  -0.984  -0.927
200   Q        -1.139  -0.840  -1.037  -0.920  -0.421  -0.759  -1.025  -0.647  -0.863
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   R        -1.262  -1.134  -1.126  -1.252  -1.084  -1.032  -1.155  -0.978  -0.956
203   D         0.602   0.460   0.505   0.843   0.628   0.694   0.470   0.195   0.257
204   N        -1.766  -1.652  -1.629  -1.604  -1.424  -1.383  -1.371  -1.220  -1.172
205   D        -1.139  -1.153  -1.105  -0.844  -0.909  -0.811  -1.025  -1.003  -0.935
206   I        -0.275  -0.224  -0.317  -0.475  -0.409  -0.567  -0.332  -0.263  -0.376
207   R        -1.139  -0.994  -1.044  -0.807  -0.581  -0.650  -1.025  -0.836  -0.869
208   L        -0.512  -0.366  -0.409  -0.591  -0.400  -0.416  -0.678  -0.485  -0.514
209   T        -1.139  -1.024  -1.044  -0.941  -0.731  -0.774  -1.025  -0.867  -0.870
210   F         0.742   0.664   0.624   0.731   0.627   0.569   0.708   0.560   0.476
211   L        -0.275  -0.208  -0.321  -0.318  -0.246  -0.361  -0.332  -0.238  -0.382
212   V        -1.139  -1.153  -1.105  -1.114  -1.047  -1.017  -1.025  -1.003  -0.935
213   F        -1.139  -1.153  -1.105  -1.151  -1.229  -1.129  -1.025  -1.003  -0.935
214   F        -1.139  -1.139  -1.102  -1.280  -1.292  -1.232  -1.025  -0.991  -0.932
215   S        -1.139  -1.033  -1.049  -1.080  -0.938  -0.930  -1.025  -0.879  -0.876
216   I        -1.766  -1.652  -1.629  -1.662  -1.420  -1.440  -1.371  -1.220  -1.172
217   I        -1.139  -1.132  -1.098  -1.320  -1.303  -1.255  -1.025  -0.984  -0.927
218   M        -1.139  -1.139  -1.102  -0.861  -0.806  -0.803  -1.025  -0.991  -0.932
219   F        -0.512  -0.501  -0.420  -0.823  -0.824  -0.669  -0.678  -0.628  -0.523
220   L        -0.275  -0.224  -0.317  -0.444  -0.401  -0.518  -0.332  -0.263  -0.376
221   W         0.742   0.949   0.693   0.971   1.269   0.911   0.708   1.030   0.598
222   I        -1.139  -1.024  -1.049  -1.422  -1.242  -1.282  -1.025  -0.869  -0.875
223   I        -0.512  -0.328  -0.414  -0.885  -0.599  -0.712  -0.678  -0.419  -0.515
224   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   Y         0.742   0.949   0.693   0.899   1.191   0.851   0.708   1.030   0.598
226   P         0.742   0.643   0.625   0.863   0.743   0.695   0.708   0.524   0.477
227   T        -1.139  -1.033  -1.049  -1.345  -1.184  -1.203  -1.025  -0.879  -0.876
228   C         0.742   0.664   0.624   0.963   0.841   0.745   0.708   0.560   0.476
229   F         0.352   0.374   0.437   0.173   0.235   0.344   0.015   0.033   0.126
230   G         0.742   0.643   0.625   0.733   0.600   0.539   0.708   0.524   0.477
231   I        -0.275  -0.438  -0.408  -0.440  -0.728  -0.686  -0.332  -0.539  -0.502
232   T         0.352   0.374   0.437   0.145   0.166   0.265   0.015   0.033   0.126
233   D         0.742   0.643   0.625   1.041   0.922   0.892   0.708   0.524   0.477
234   G         1.874   1.951   1.995   1.848   1.986   2.049   2.094   2.196   2.279
235   G         0.742   0.643   0.625   0.728   0.578   0.530   0.708   0.524   0.477
236   N         1.874   1.951   1.995   2.020   2.140   2.221   2.094   2.196   2.279
237   V         1.874   1.951   1.995   1.766   1.871   1.968   2.094   2.196   2.279
238   L         0.352   0.374   0.437  -0.072  -0.059   0.055   0.015   0.033   0.126
239   Q        -0.275  -0.438  -0.408  -0.025  -0.307  -0.282  -0.332  -0.539  -0.502
240   P         0.742   0.664   0.624   0.820   0.716   0.625   0.708   0.560   0.476
241   D        -0.275  -0.438  -0.408  -0.077  -0.344  -0.340  -0.332  -0.539  -0.502
242   S        -0.275  -0.438  -0.408  -0.231  -0.473  -0.436  -0.332  -0.539  -0.502
243   A        -0.512  -0.501  -0.420  -0.614  -0.553  -0.416  -0.678  -0.628  -0.523
244   G        -1.139  -1.014  -1.047  -1.284  -1.057  -1.123  -1.025  -0.857  -0.873
245   I         1.874   1.951   1.995   1.737   1.874   1.939   2.094   2.196   2.279
246   F         1.874   1.951   1.995   1.795   1.914   1.996   2.094   2.196   2.279
247   Y         0.742   0.664   0.624   0.839   0.720   0.648   0.708   0.560   0.476
248   G         0.742   0.643   0.625   0.760   0.627   0.583   0.708   0.524   0.477
249   I         1.874   1.951   1.995   1.737   1.874   1.939   2.094   2.196   2.279
250   I         0.352   0.507   0.518  -0.072   0.188   0.214   0.015   0.282   0.280
251   D         1.874   1.951   1.995   2.067   2.196   2.267   2.094   2.196   2.279
252   L        -0.275  -0.208  -0.321  -0.453  -0.383  -0.538  -0.332  -0.238  -0.382
253   I        -0.512  -0.511  -0.422  -0.874  -0.864  -0.712  -0.678  -0.640  -0.525
254   L        -0.275  -0.438  -0.408  -0.317  -0.559  -0.484  -0.332  -0.539  -0.502
255   M        -1.766  -1.652  -1.629  -1.730  -1.571  -1.508  -1.371  -1.220  -1.172
256   C        -1.139  -1.014  -1.047  -1.105  -0.874  -0.952  -1.025  -0.857  -0.873
257   F        -0.275  -0.221  -0.325  -0.336  -0.231  -0.419  -0.332  -0.254  -0.387
258   I        -0.512  -0.396  -0.411  -0.852  -0.682  -0.682  -0.678  -0.516  -0.516
259   P        -0.275  -0.438  -0.408  -0.187  -0.438  -0.422  -0.332  -0.539  -0.502
260   T        -1.139  -1.014  -1.047  -1.144  -0.967  -0.974  -1.025  -0.857  -0.873
261   L         0.352   0.374   0.437  -0.119  -0.142  -0.007   0.015   0.033   0.126
262   L        -1.139  -0.840  -1.037  -1.130  -0.683  -0.961  -1.025  -0.647  -0.863
263   V         0.742   0.643   0.625   0.679   0.516   0.505   0.708   0.524   0.477
264   P        -0.275  -0.438  -0.408  -0.152  -0.395  -0.367  -0.332  -0.539  -0.502
265   I        -0.512  -0.501  -0.420  -0.660  -0.601  -0.484  -0.678  -0.628  -0.523
266   A        -0.275  -0.438  -0.408  -0.490  -0.785  -0.711  -0.332  -0.539  -0.502
267   N        -1.139  -1.153  -1.105  -0.912  -0.891  -0.811  -1.025  -1.003  -0.935
268   H        -1.139  -1.132  -1.098  -0.873  -0.912  -0.829  -1.025  -0.984  -0.927
269   F        -1.139  -1.014  -1.047  -1.208  -0.985  -1.053  -1.025  -0.857  -0.873
270   G         0.742   0.664   0.624   0.815   0.742   0.670   0.708   0.560   0.476
271   A        -0.512  -0.396  -0.409  -0.757  -0.557  -0.591  -0.678  -0.516  -0.514
272   D        -0.512  -0.396  -0.411  -0.411  -0.245  -0.233  -0.678  -0.516  -0.516
273   K        -0.275  -0.247  -0.331  -0.010   0.047  -0.084  -0.332  -0.287  -0.396
274   L        -1.139  -1.004  -1.045  -1.248  -1.071  -1.089  -1.025  -0.849  -0.871
275   G        -0.478  -0.463  -0.451  -0.555  -0.497  -0.502  -0.613  -0.586  -0.560
276   Y         0.602   0.461   0.505   0.624   0.361   0.410   0.470   0.197   0.257
277   H        -1.262  -1.135  -1.126  -1.239  -1.114  -1.019  -1.155  -0.978  -0.956
278   F         0.602   0.774   0.580   0.470   0.757   0.415   0.470   0.748   0.395
279   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   S         0.434   0.504   0.464   0.277   0.391   0.293   0.169   0.275   0.178
282   D         1.874   1.951   1.995   2.059   2.180   2.259   2.094   2.196   2.279
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   A         1.874   1.951   1.995   1.691   1.814   1.893   2.094   2.196   2.279
290   E         0.434   0.504   0.464   0.534   0.651   0.539   0.169   0.275   0.178
291   A         0.434   0.504   0.464   0.094   0.213   0.127   0.169   0.275   0.178
292   V         0.434   0.477   0.460   0.211   0.280   0.231   0.169   0.226   0.171
293   M         1.874   1.951   1.995   2.002   2.126   2.203   2.094   2.196   2.279
294   A         0.434   0.528   0.468   0.100   0.262   0.143   0.169   0.320   0.186
295   P        -0.611  -0.549  -0.479  -0.660  -0.548  -0.445  -0.794  -0.688  -0.597
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   K        -0.512  -0.495  -0.418  -0.451  -0.380  -0.297  -0.678  -0.620  -0.519
300   A        -1.139  -1.139  -1.102  -1.107  -1.079  -0.983  -1.025  -0.991  -0.932
301   P        -1.139  -0.994  -1.044  -1.073  -0.800  -0.922  -1.025  -0.836  -0.869
302   V        -1.139  -1.139  -1.102  -1.000  -0.973  -0.888  -1.025  -0.991  -0.932
303   A        -1.139  -1.139  -1.102  -1.182  -1.149  -1.071  -1.025  -0.991  -0.932
304   S        -0.275  -0.438  -0.408  -0.325  -0.626  -0.582  -0.332  -0.539  -0.502
305   P         1.874   1.951   1.995   1.929   2.069   2.130   2.094   2.196   2.279
306   R        -1.766  -1.652  -1.629  -1.745  -1.611  -1.523  -1.371  -1.220  -1.172
307   P        -1.766  -1.652  -1.629  -1.681  -1.531  -1.459  -1.371  -1.220  -1.172
308   A        -0.275  -0.208  -0.321  -0.446  -0.352  -0.507  -0.332  -0.238  -0.382
309   A        -1.139  -1.024  -1.049  -1.054  -0.811  -0.905  -1.025  -0.869  -0.875
310   T        -0.512  -0.501  -0.420  -0.613  -0.570  -0.448  -0.678  -0.628  -0.523
311   P         0.742   0.949   0.693   0.840   1.162   0.774   0.708   1.030   0.598
312   N        -1.766  -1.652  -1.629  -1.502  -1.334  -1.281  -1.371  -1.220  -1.172
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   K         0.434   0.492   0.523   0.445   0.545   0.586   0.169   0.255   0.290
321   D         0.434   0.498   0.525   0.585   0.695   0.732   0.169   0.265   0.293
322   K        -1.139  -1.153  -1.105  -1.067  -1.066  -1.010  -1.025  -1.003  -0.935
323   K        -1.139  -1.153  -1.105  -0.915  -0.877  -0.839  -1.025  -1.003  -0.935
324   K        -1.139  -1.139  -1.102  -1.158  -1.172  -1.134  -1.025  -0.991  -0.932
325   K        -1.766  -1.652  -1.629  -1.415  -1.168  -1.195  -1.371  -1.220  -1.172
326   S        -0.275  -0.263  -0.335  -0.134  -0.089  -0.219  -0.332  -0.311  -0.401
327   K        -1.139  -1.139  -1.102  -0.841  -0.769  -0.753  -1.025  -0.991  -0.932
328   K        -1.766  -1.652  -1.629  -1.706  -1.557  -1.485  -1.371  -1.220  -1.172
329   S        -1.766  -1.652  -1.629  -1.522  -1.299  -1.301  -1.371  -1.220  -1.172
330   K        -1.139  -1.153  -1.105  -1.206  -1.183  -1.102  -1.025  -1.003  -0.935
331   K        -1.139  -1.033  -1.049  -1.125  -0.963  -0.983  -1.025  -0.879  -0.876
332   S        -1.766  -1.652  -1.629  -1.769  -1.560  -1.547  -1.371  -1.220  -1.172
333   K        -0.275  -0.438  -0.408  -0.165  -0.415  -0.402  -0.332  -0.539  -0.502
334   K        -0.275  -0.438  -0.408  -0.001  -0.185  -0.152  -0.332  -0.539  -0.502
335   S        -1.139  -0.840  -1.037  -1.159  -0.632  -0.999  -1.025  -0.647  -0.863
336   K        -0.275  -0.438  -0.408  -0.161  -0.412  -0.396  -0.332  -0.539  -0.502
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   K         0.742   0.664   0.624   0.818   0.710   0.606   0.708   0.560   0.476
349   S        -1.139  -1.139  -1.102  -1.100  -1.067  -1.032  -1.025  -0.991  -0.932
350   E        -1.766  -1.652  -1.629  -1.446  -1.304  -1.225  -1.371  -1.220  -1.172
351   E        -1.766  -1.652  -1.629  -1.541  -1.337  -1.320  -1.371  -1.220  -1.172
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12117
Output conservation file - output/Q12117
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
