1     M         2.268   2.283   2.344   2.563   2.586   2.688   2.559   2.583   2.678
2     I        -0.339  -0.298  -0.375  -0.299  -0.235  -0.350  -0.333  -0.281  -0.372
3     K        -0.522  -0.522  -0.513  -0.401  -0.405  -0.362  -0.574  -0.571  -0.545
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -         0.087   0.157   0.118   0.071   0.189   0.110  -0.152  -0.048  -0.116
6     -        -1.109  -1.102  -1.048  -1.013  -0.990  -0.920  -0.911  -0.903  -0.831
7     L         2.268   2.283   2.344   1.930   1.951   2.050   2.559   2.583   2.678
8     H        -0.522  -0.492  -0.494  -0.349  -0.310  -0.300  -0.574  -0.542  -0.525
9     E        -0.339  -0.401  -0.409  -0.025  -0.133  -0.151  -0.333  -0.410  -0.414
10    V         1.323   1.297   1.208   1.365   1.327   1.163   1.354   1.308   1.125
11    P        -1.006  -1.028  -0.981  -0.900  -0.920  -0.851  -0.815  -0.834  -0.769
12    P         2.268   2.283   2.344   2.389   2.412   2.512   2.559   2.583   2.678
13    E        -0.522  -0.522  -0.497  -0.431  -0.439  -0.391  -0.574  -0.571  -0.528
14    P         2.268   2.283   2.344   2.389   2.412   2.512   2.559   2.583   2.678
15    V        -1.006  -1.018  -0.978  -1.171  -1.197  -1.110  -0.815  -0.825  -0.766
16    D        -0.522  -0.533  -0.499  -0.365  -0.381  -0.316  -0.574  -0.583  -0.531
17    P        -0.527  -0.569  -0.529  -0.305  -0.363  -0.293  -0.564  -0.612  -0.557
18    A        -0.640  -0.627  -0.578  -0.558  -0.522  -0.460  -0.694  -0.678  -0.612
19    S        -0.640  -0.627  -0.578  -0.571  -0.550  -0.474  -0.694  -0.678  -0.612
20    L        -0.640  -0.627  -0.578  -0.897  -0.860  -0.803  -0.694  -0.678  -0.612
21    P         0.087   0.044   0.083   0.085   0.001   0.074  -0.152  -0.217  -0.167
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    H        -1.109  -1.101  -1.048  -0.811  -0.797  -0.716  -0.911  -0.902  -0.831
25    D         0.856   0.841   0.894   0.735   0.687   0.759   0.477   0.440   0.508
26    V        -1.109  -1.101  -1.048  -1.121  -1.085  -1.029  -0.911  -0.902  -0.831
27    N         1.218   1.141   1.124   1.421   1.300   1.266   1.171   1.026   0.968
28    A         0.274   0.327   0.243   0.269   0.360   0.192   0.130   0.208   0.073
29    H        -0.527  -0.562  -0.533  -0.529  -0.578  -0.521  -0.564  -0.604  -0.562
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    S        -0.527  -0.474  -0.497  -0.563  -0.466  -0.532  -0.564  -0.499  -0.520
36    P         2.268   2.283   2.344   2.400   2.422   2.524   2.559   2.583   2.678
37    E        -0.527  -0.499  -0.516  -0.369  -0.325  -0.370  -0.564  -0.530  -0.543
38    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    G         0.087   0.104   0.118   0.052   0.075   0.092  -0.152  -0.127  -0.116
41    N        -0.640  -0.638  -0.578  -0.470  -0.461  -0.372  -0.694  -0.689  -0.612
42    P         1.088   1.111   1.072   1.134   1.170   1.097   0.933   0.970   0.866
43    D        -0.640  -0.638  -0.578  -0.449  -0.449  -0.351  -0.694  -0.689  -0.612
44    K         1.088   1.111   1.072   0.944   0.984   0.875   0.933   0.970   0.866
45    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    S         0.055   0.020   0.072  -0.039  -0.087  -0.002  -0.217  -0.258  -0.190
57    R        -0.527  -0.501  -0.512  -0.335  -0.289  -0.317  -0.564  -0.531  -0.538
58    S        -0.527  -0.475  -0.492  -0.522  -0.453  -0.462  -0.564  -0.500  -0.514
59    S        -0.527  -0.495  -0.506  -0.379  -0.311  -0.370  -0.564  -0.524  -0.530
60    C         0.274   0.284   0.190   0.053   0.067  -0.047   0.130   0.144  -0.007
61    R        -1.006  -1.018  -0.978  -0.993  -0.997  -0.959  -0.815  -0.825  -0.766
62    R        -0.522  -0.489  -0.487  -0.380  -0.329  -0.317  -0.574  -0.538  -0.519
63    F        -1.491  -1.485  -1.432  -1.353  -1.374  -1.263  -1.056  -1.048  -0.978
64    L         2.268   2.283   2.344   1.930   1.951   2.050   2.559   2.583   2.678
65    W        -1.006  -1.030  -1.009  -0.614  -0.656  -0.602  -0.815  -0.836  -0.795
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    N        -1.006  -1.028  -0.981  -0.736  -0.768  -0.685  -0.815  -0.834  -0.769
70    C        -1.006  -0.942  -0.976  -0.927  -0.814  -0.891  -0.815  -0.746  -0.764
71    Q         2.268   2.283   2.344   2.589   2.614   2.715   2.559   2.583   2.678
72    K         1.323   1.354   1.213   1.446   1.492   1.303   1.354   1.406   1.135
73    I        -0.339  -0.319  -0.427  -0.218  -0.173  -0.395  -0.333  -0.306  -0.436
74    S         2.268   2.283   2.344   2.209   2.234   2.331   2.559   2.583   2.678
75    V        -0.339  -0.319  -0.427  -0.335  -0.319  -0.536  -0.333  -0.306  -0.436
76    L        -0.522  -0.487  -0.505  -0.540  -0.474  -0.533  -0.574  -0.534  -0.536
77    P        -0.339  -0.344  -0.429  -0.314  -0.349  -0.508  -0.333  -0.341  -0.438
78    M         0.146   0.143   0.130   0.180   0.170   0.127  -0.092  -0.089  -0.108
79    A        -1.006  -1.024  -1.005  -0.940  -0.969  -0.958  -0.815  -0.830  -0.792
80    L        -0.522  -0.569  -0.524  -0.878  -0.933  -0.851  -0.574  -0.619  -0.557
81    Y         0.814   0.822   0.883   0.731   0.741   0.840   0.390   0.401   0.485
82    F         0.814   0.822   0.883   0.372   0.378   0.477   0.390   0.401   0.485
83    P         0.814   0.822   0.883   0.585   0.595   0.693   0.390   0.401   0.485
84    L         0.448   0.495   0.333   0.138   0.211  -0.042   0.390   0.461   0.210
85    H         2.268   2.283   2.344   2.515   2.539   2.640   2.559   2.583   2.678
86    A         0.448   0.466   0.338   0.535   0.556   0.332   0.390   0.416   0.218
87    A        -0.339  -0.319  -0.427  -0.173  -0.151  -0.335  -0.333  -0.306  -0.436
88    N         0.146   0.111   0.130   0.143   0.109   0.124  -0.092  -0.129  -0.108
89    T         0.146   0.143   0.130   0.129   0.126   0.115  -0.092  -0.089  -0.108
90    L        -0.522  -0.487  -0.504  -0.856  -0.807  -0.800  -0.574  -0.537  -0.536
91    I         0.448   0.400   0.309   0.341   0.275   0.091   0.390   0.316   0.174
92    T        -0.522  -0.569  -0.524  -0.518  -0.592  -0.524  -0.574  -0.619  -0.557
93    P         2.268   2.283   2.344   2.389   2.412   2.512   2.559   2.583   2.678
94    A        -0.522  -0.484  -0.495  -0.860  -0.827  -0.837  -0.574  -0.534  -0.526
95    V         0.146   0.107   0.147  -0.250  -0.294  -0.227  -0.092  -0.136  -0.084
96    S        -1.006  -0.983  -0.990  -0.842  -0.799  -0.809  -0.815  -0.789  -0.777
97    P        -0.339  -0.344  -0.429  -0.151  -0.146  -0.299  -0.333  -0.341  -0.438
98    D        -0.339  -0.312  -0.376  -0.024   0.016  -0.088  -0.333  -0.298  -0.373
99    S        -1.006  -1.000  -0.994  -0.767  -0.773  -0.721  -0.815  -0.807  -0.781
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   A        -0.527  -0.550  -0.529  -0.624  -0.664  -0.675  -0.564  -0.590  -0.557
102   P         0.146   0.158   0.128   0.137   0.143   0.107  -0.092  -0.081  -0.115
103   D         0.146   0.158   0.141   0.363   0.364   0.368  -0.092  -0.090  -0.099
104   D        -0.522  -0.545  -0.517  -0.342  -0.378  -0.349  -0.574  -0.596  -0.549
105   V        -1.006  -1.026  -0.980  -0.868  -0.895  -0.827  -0.815  -0.832  -0.768
106   L         0.933   0.976   0.985   0.494   0.557   0.574   0.631   0.710   0.694
107   M        -1.006  -1.000  -0.994  -0.656  -0.668  -0.645  -0.815  -0.807  -0.781
108   M         0.448   0.395   0.314   0.840   0.760   0.639   0.390   0.310   0.180
109   V        -0.339  -0.344  -0.429  -0.220  -0.228  -0.371  -0.333  -0.341  -0.438
110   R         0.448   0.495   0.333   0.748   0.820   0.579   0.390   0.461   0.210
111   E         0.146   0.154   0.151   0.259   0.261   0.266  -0.092  -0.086  -0.081
112   I        -0.522  -0.523  -0.503  -0.690  -0.705  -0.667  -0.574  -0.572  -0.533
113   L        -0.339  -0.319  -0.427  -0.234  -0.195  -0.416  -0.333  -0.306  -0.436
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   P         1.323   1.297   1.208   1.470   1.436   1.294   1.354   1.308   1.125
118   S        -1.491  -1.485  -1.432  -1.371  -1.354  -1.281  -1.056  -1.048  -0.978
119   I        -1.006  -0.969  -0.970  -0.998  -0.954  -0.952  -0.815  -0.775  -0.758
120   T        -0.339  -0.319  -0.427  -0.014   0.013  -0.169  -0.333  -0.306  -0.436
121   T        -0.339  -0.254  -0.374  -0.255  -0.132  -0.297  -0.333  -0.224  -0.370
122   K         0.146   0.169   0.128  -0.153  -0.119  -0.224  -0.092  -0.070  -0.115
123   L         0.146   0.189   0.153  -0.267  -0.204  -0.228  -0.092  -0.027  -0.080
124   L         0.146   0.107   0.147  -0.295  -0.334  -0.287  -0.092  -0.136  -0.084
125   V        -0.339  -0.392  -0.412  -0.242  -0.307  -0.331  -0.333  -0.399  -0.417
126   A         0.146   0.143   0.130   0.085   0.077   0.074  -0.092  -0.089  -0.108
127   G         0.146   0.093   0.138  -0.052  -0.129  -0.055  -0.092  -0.159  -0.099
128   I        -0.339  -0.268  -0.385  -0.533  -0.403  -0.641  -0.333  -0.241  -0.384
129   T        -1.491  -1.485  -1.432  -1.632  -1.619  -1.544  -1.056  -1.048  -0.978
130   L        -1.006  -0.972  -0.984  -0.910  -0.866  -0.886  -0.815  -0.777  -0.772
131   H         2.268   2.283   2.344   2.515   2.539   2.640   2.559   2.583   2.678
132   V         0.146   0.089   0.136  -0.131  -0.242  -0.183  -0.092  -0.165  -0.103
133   S        -1.006  -0.942  -0.976  -1.031  -0.974  -0.961  -0.815  -0.746  -0.764
134   A         0.933   0.971   0.951   0.726   0.786   0.745   0.631   0.702   0.624
135   G         2.268   2.283   2.344   2.291   2.311   2.414   2.559   2.583   2.678
136   V        -0.522  -0.569  -0.524  -0.511  -0.547  -0.476  -0.574  -0.619  -0.557
137   L        -0.522  -0.522  -0.513  -0.898  -0.886  -0.865  -0.574  -0.571  -0.545
138   L         0.933   0.976   0.985   0.364   0.440   0.438   0.631   0.710   0.694
139   R         2.268   2.283   2.344   2.471   2.496   2.596   2.559   2.583   2.678
140   I         0.448   0.516   0.345   0.329   0.444   0.141   0.390   0.491   0.228
141   V        -1.491  -1.485  -1.432  -1.079  -1.051  -0.987  -1.056  -1.048  -0.978
142   N         0.146   0.182   0.158   0.162   0.212   0.194  -0.092  -0.045  -0.073
143   N        -1.006  -0.994  -0.970  -0.993  -0.951  -0.943  -0.815  -0.801  -0.758
144   W        -1.491  -1.485  -1.432  -1.142  -1.164  -1.050  -1.056  -1.048  -0.978
145   N        -1.491  -1.485  -1.432  -1.315  -1.278  -1.225  -1.056  -1.048  -0.978
146   K        -0.640  -0.634  -0.578  -0.593  -0.562  -0.496  -0.694  -0.685  -0.612
147   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   R        -0.339  -0.319  -0.427  -0.303  -0.269  -0.467  -0.333  -0.306  -0.436
150   N        -1.006  -1.018  -0.978  -0.810  -0.834  -0.760  -0.815  -0.825  -0.766
151   R        -1.006  -0.983  -0.990  -0.848  -0.821  -0.814  -0.815  -0.789  -0.777
152   H        -0.522  -0.490  -0.505  -0.410  -0.358  -0.379  -0.574  -0.540  -0.536
153   R        -1.491  -1.485  -1.432  -1.317  -1.348  -1.227  -1.056  -1.048  -0.978
154   H         1.323   1.244   1.199   1.616   1.502   1.433   1.354   1.213   1.109
155   L        -1.006  -1.024  -1.005  -1.161  -1.174  -1.118  -0.815  -0.830  -0.792
156   K        -1.006  -0.983  -0.990  -0.870  -0.841  -0.828  -0.815  -0.789  -0.777
157   -         0.087   0.072   0.101   0.125   0.110   0.154  -0.152  -0.176  -0.140
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   I        -0.527  -0.537  -0.501  -0.779  -0.819  -0.747  -0.564  -0.574  -0.525
164   S        -1.109  -1.105  -1.048  -1.281  -1.300  -1.191  -0.911  -0.905  -0.831
165   A        -1.109  -1.105  -1.048  -0.779  -0.767  -0.683  -0.911  -0.905  -0.831
166   E         0.087   0.114   0.115   0.084   0.119   0.131  -0.152  -0.113  -0.120
167   Q         0.087   0.079   0.097   0.110   0.063   0.091  -0.152  -0.166  -0.147
168   D        -1.109  -1.105  -1.048  -0.837  -0.843  -0.742  -0.911  -0.905  -0.831
169   L         0.055   0.070   0.077  -0.214  -0.203  -0.182  -0.217  -0.198  -0.182
170   S        -0.527  -0.550  -0.529  -0.433  -0.457  -0.407  -0.564  -0.590  -0.557
171   Q         0.274   0.284   0.189   0.642   0.660   0.505   0.130   0.145  -0.009
172   D         1.218   1.169   1.124   1.440   1.360   1.273   1.171   1.078   0.968
173   S        -0.527  -0.537  -0.503  -0.309  -0.318  -0.278  -0.564  -0.575  -0.527
174   I         2.268   2.283   2.344   2.161   2.181   2.283   2.559   2.583   2.678
175   G         2.268   2.283   2.344   2.307   2.327   2.430   2.559   2.583   2.678
176   L         1.218   1.221   1.134   0.898   0.899   0.782   1.171   1.172   0.986
177   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   G         2.268   2.283   2.344   2.307   2.327   2.430   2.559   2.583   2.678
179   G         2.268   2.283   2.344   2.307   2.327   2.430   2.559   2.583   2.678
180   I         1.218   1.169   1.124   1.012   0.918   0.817   1.171   1.078   0.968
181   S         1.218   1.241   1.141   1.181   1.218   1.069   1.171   1.209   0.999
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   G         2.268   2.283   2.344   2.307   2.327   2.430   2.559   2.583   2.678
188   Y         2.268   2.283   2.344   2.454   2.477   2.578   2.559   2.583   2.678
189   L         0.055   0.032   0.072  -0.247  -0.265  -0.208  -0.217  -0.244  -0.190
190   F         0.055   0.032   0.072  -0.078  -0.124  -0.065  -0.217  -0.244  -0.190
191   G         0.856   0.866   0.913   0.563   0.576   0.642   0.477   0.491   0.547
192   L        -0.527  -0.502  -0.511  -0.708  -0.662  -0.685  -0.564  -0.532  -0.536
193   Y        -0.527  -0.550  -0.529  -0.482  -0.527  -0.510  -0.564  -0.590  -0.557
194   K        -0.527  -0.550  -0.529  -0.559  -0.588  -0.570  -0.564  -0.590  -0.557
195   T        -0.527  -0.527  -0.500  -0.188  -0.187  -0.148  -0.564  -0.564  -0.523
196   F         0.856   0.851   0.900   0.533   0.501   0.557   0.477   0.461   0.520
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   R        -1.006  -1.030  -1.009  -0.730  -0.760  -0.707  -0.815  -0.836  -0.795
200   I         0.146   0.115   0.138  -0.345  -0.385  -0.341  -0.092  -0.135  -0.104
201   P        -0.339  -0.315  -0.387  -0.255  -0.216  -0.316  -0.333  -0.301  -0.387
202   P         1.323   1.244   1.199   1.490   1.378   1.309   1.354   1.213   1.109
203   Q         0.146   0.093   0.138  -0.169  -0.241  -0.167  -0.092  -0.159  -0.099
204   V        -1.006  -0.969  -0.970  -0.992  -0.916  -0.933  -0.815  -0.775  -0.758
205   I        -0.522  -0.487  -0.505  -0.715  -0.697  -0.700  -0.574  -0.534  -0.536
206   S         0.933   0.892   0.930   0.736   0.662   0.721   0.631   0.543   0.582
207   G         2.268   2.283   2.344   2.291   2.311   2.414   2.559   2.583   2.678
208   Y         0.448   0.348   0.298   0.790   0.654   0.597   0.390   0.241   0.156
209   I        -0.522  -0.538  -0.492  -0.802  -0.805  -0.747  -0.574  -0.588  -0.524
210   L         1.323   1.244   1.199   1.062   0.955   0.899   1.354   1.213   1.109
211   V        -0.339  -0.254  -0.374  -0.315  -0.163  -0.406  -0.333  -0.224  -0.370
212   P         2.268   2.283   2.344   2.389   2.412   2.512   2.559   2.583   2.678
213   V        -0.522  -0.543  -0.502  -0.847  -0.872  -0.816  -0.574  -0.593  -0.534
214   L        -0.522  -0.498  -0.507  -0.902  -0.867  -0.857  -0.574  -0.548  -0.539
215   I        -1.006  -1.026  -0.980  -1.146  -1.164  -1.111  -0.815  -0.832  -0.768
216   Y         0.448   0.348   0.298   0.688   0.532   0.456   0.390   0.241   0.156
217   H         2.268   2.283   2.344   2.515   2.539   2.640   2.559   2.583   2.678
218   L        -1.006  -1.024  -1.005  -1.184  -1.220  -1.143  -0.815  -0.830  -0.792
219   L        -0.522  -0.480  -0.504  -0.721  -0.654  -0.653  -0.574  -0.528  -0.535
220   I        -0.522  -0.569  -0.524  -0.813  -0.887  -0.841  -0.574  -0.619  -0.557
221   M         0.146   0.111   0.130   0.337   0.294   0.320  -0.092  -0.129  -0.108
222   K         0.814   0.822   0.883   0.661   0.677   0.770   0.390   0.401   0.485
223   W        -0.339  -0.344  -0.429   0.009  -0.030  -0.164  -0.333  -0.341  -0.438
224   V         0.146   0.147   0.158  -0.131  -0.118  -0.129  -0.092  -0.081  -0.067
225   P         2.268   2.283   2.344   2.389   2.412   2.512   2.559   2.583   2.678
226   N        -1.006  -1.000  -0.994  -0.814  -0.831  -0.809  -0.815  -0.807  -0.781
227   S        -1.006  -1.024  -1.005  -1.005  -1.017  -0.996  -0.815  -0.830  -0.792
228   I        -1.006  -1.036  -0.980  -1.110  -1.149  -1.073  -0.815  -0.841  -0.768
229   -         0.087   0.034   0.079   0.073  -0.042   0.016  -0.152  -0.231  -0.174
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   S         0.448   0.441   0.319   0.500   0.493   0.319   0.390   0.380   0.188
233   T        -0.339  -0.319  -0.427  -0.302  -0.272  -0.433  -0.333  -0.306  -0.436
234   E        -1.006  -1.030  -1.009  -1.017  -1.037  -0.959  -0.815  -0.836  -0.795
235   V         0.146   0.152   0.143  -0.032  -0.024  -0.027  -0.092  -0.089  -0.096
236   D        -0.522  -0.545  -0.517  -0.383  -0.427  -0.389  -0.574  -0.596  -0.549
237   F         0.814   0.822   0.883   0.372   0.378   0.477   0.390   0.401   0.485
238   A         0.448   0.512   0.337   0.815   0.907   0.659   0.390   0.486   0.215
239   S         0.146   0.175   0.129   0.172   0.213   0.137  -0.092  -0.057  -0.114
240   I         0.933   0.935   0.952   0.683   0.688   0.699   0.631   0.629   0.626
241   K        -0.339  -0.344  -0.429  -0.277  -0.292  -0.435  -0.333  -0.341  -0.438
242   Q        -0.522  -0.569  -0.524  -0.172  -0.226  -0.149  -0.574  -0.619  -0.557
243   L         0.448   0.521   0.333   0.202   0.304   0.042   0.390   0.499   0.209
244   L         1.323   1.244   1.199   1.050   0.938   0.882   1.354   1.213   1.109
245   S        -0.522  -0.487  -0.505  -0.325  -0.264  -0.297  -0.574  -0.534  -0.536
246   S        -1.006  -1.005  -0.977  -1.051  -1.030  -1.016  -0.815  -0.812  -0.765
247   K        -0.522  -0.569  -0.495  -0.528  -0.570  -0.467  -0.574  -0.619  -0.527
248   N        -0.339  -0.275  -0.390   0.053   0.149  -0.011  -0.333  -0.250  -0.390
249   R        -1.109  -1.105  -1.048  -1.078  -1.080  -0.986  -0.911  -0.905  -0.831
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   W         0.087   0.046   0.083   0.030  -0.064  -0.042  -0.152  -0.213  -0.167
252   W         0.087   0.114   0.112  -0.007   0.023   0.038  -0.152  -0.112  -0.125
253   K         0.087   0.086   0.103   0.063   0.055   0.070  -0.152  -0.155  -0.138
254   W         0.087   0.046   0.083   0.232   0.155   0.196  -0.152  -0.213  -0.167
255   L        -1.006  -0.978  -0.972  -1.121  -1.097  -1.052  -0.815  -0.784  -0.760
256   G        -1.006  -0.942  -0.976  -1.187  -1.112  -1.125  -0.815  -0.746  -0.764
257   G         0.933   0.976   0.985   0.841   0.908   0.921   0.631   0.710   0.694
258   L        -1.006  -1.005  -0.977  -0.996  -0.971  -0.969  -0.815  -0.812  -0.765
259   V        -0.522  -0.522  -0.497  -0.534  -0.525  -0.501  -0.574  -0.571  -0.528
260   P         0.814   0.822   0.883   0.664   0.667   0.772   0.390   0.401   0.485
261   L         2.268   2.283   2.344   1.930   1.951   2.050   2.559   2.583   2.678
262   A        -1.491  -1.485  -1.432  -1.242  -1.235  -1.151  -1.056  -1.048  -0.978
263   I        -0.522  -0.490  -0.505  -0.557  -0.521  -0.529  -0.574  -0.540  -0.536
264   L         1.323   1.244   1.199   1.006   0.889   0.815   1.354   1.213   1.109
265   L        -0.339  -0.335  -0.380  -0.468  -0.453  -0.555  -0.333  -0.329  -0.378
266   E        -1.491  -1.485  -1.432  -1.255  -1.247  -1.164  -1.056  -1.048  -0.978
267   S        -0.522  -0.524  -0.499  -0.867  -0.880  -0.842  -0.574  -0.573  -0.531
268   G        -0.339  -0.364  -0.393  -0.153  -0.200  -0.221  -0.333  -0.364  -0.394
269   V         0.448   0.412   0.322   0.444   0.388   0.247   0.390   0.333   0.192
270   Y         1.323   1.244   1.199   1.459   1.328   1.241   1.354   1.213   1.109
271   H         2.268   2.283   2.344   2.515   2.539   2.640   2.559   2.583   2.678
272   I        -0.339  -0.344  -0.429  -0.337  -0.346  -0.474  -0.333  -0.341  -0.438
273   G        -1.006  -1.028  -0.981  -1.011  -1.060  -0.983  -0.815  -0.834  -0.769
274   S         0.146   0.196   0.160   0.089   0.170   0.115  -0.092  -0.017  -0.071
275   G         2.268   2.283   2.344   2.291   2.311   2.414   2.559   2.583   2.678
276   L        -0.339  -0.312  -0.376  -0.532  -0.502  -0.568  -0.333  -0.298  -0.373
277   C        -1.006  -1.024  -1.005  -0.726  -0.756  -0.764  -0.815  -0.830  -0.792
278   R         0.146   0.143   0.130   0.191   0.197   0.196  -0.092  -0.089  -0.108
279   Y         0.146   0.093   0.138  -0.191  -0.254  -0.175  -0.092  -0.159  -0.099
280   F        -1.006  -0.969  -0.970  -1.046  -1.005  -0.972  -0.815  -0.775  -0.758
281   G        -0.522  -0.546  -0.493  -0.347  -0.373  -0.288  -0.574  -0.596  -0.525
282   V         0.933   0.976   0.985   0.802   0.881   0.878   0.631   0.710   0.694
283   R        -0.037  -0.029   0.033  -0.101  -0.094   0.002  -0.333  -0.322  -0.240
284   K         0.448   0.507   0.321   0.495   0.583   0.316   0.390   0.479   0.192
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   M        -0.037  -0.030   0.031  -0.344  -0.340  -0.263  -0.333  -0.323  -0.243
289   T        -0.037  -0.031   0.029  -0.099  -0.090   0.003  -0.333  -0.324  -0.246
290   S        -1.491  -1.485  -1.432  -1.401  -1.429  -1.311  -1.056  -1.048  -0.978
291   R         0.146   0.111   0.130   0.196   0.161   0.181  -0.092  -0.129  -0.108
292   K         2.268   2.283   2.344   2.312   2.336   2.435   2.559   2.583   2.678
293   K        -1.006  -1.030  -1.009  -0.886  -0.906  -0.864  -0.815  -0.836  -0.795
294   W        -0.339  -0.319  -0.427  -0.207  -0.190  -0.338  -0.333  -0.306  -0.436
295   S        -0.522  -0.510  -0.509  -0.809  -0.801  -0.763  -0.574  -0.560  -0.541
296   T        -1.006  -1.036  -0.980  -0.683  -0.732  -0.636  -0.815  -0.841  -0.768
297   A        -0.522  -0.498  -0.488  -0.475  -0.446  -0.427  -0.574  -0.548  -0.520
298   I         0.448   0.400   0.309   0.465   0.401   0.262   0.390   0.316   0.174
299   N        -1.006  -1.026  -0.980  -0.977  -1.017  -0.959  -0.815  -0.832  -0.768
300   L         0.146   0.093   0.138  -0.187  -0.275  -0.205  -0.092  -0.159  -0.099
301   L         0.448   0.400   0.309   0.194   0.122  -0.004   0.390   0.316   0.174
302   T         0.146   0.115   0.138  -0.036  -0.083  -0.048  -0.092  -0.135  -0.104
303   L        -0.522  -0.569  -0.495  -0.814  -0.852  -0.750  -0.574  -0.619  -0.527
304   V        -1.006  -1.030  -1.009  -1.211  -1.245  -1.175  -0.815  -0.836  -0.795
305   G         1.323   1.244   1.199   1.411   1.295   1.239   1.354   1.213   1.109
306   F        -1.006  -1.024  -1.005  -0.614  -0.664  -0.600  -0.815  -0.830  -0.792
307   V         0.448   0.507   0.321   0.341   0.439   0.113   0.390   0.479   0.192
308   S         0.448   0.348   0.298   0.509   0.374   0.299   0.390   0.241   0.156
309   L        -0.522  -0.542  -0.499  -0.910  -0.914  -0.864  -0.574  -0.592  -0.531
310   I        -1.006  -1.036  -0.980  -1.152  -1.180  -1.119  -0.815  -0.841  -0.768
311   R         1.323   1.360   1.214   1.501   1.560   1.311   1.354   1.415   1.138
312   L         0.146   0.111   0.130  -0.143  -0.180  -0.128  -0.092  -0.129  -0.108
313   M        -0.522  -0.487  -0.505  -0.562  -0.515  -0.525  -0.574  -0.534  -0.536
314   K        -1.109  -1.102  -1.048  -0.891  -0.872  -0.797  -0.911  -0.902  -0.831
315   E        -0.527  -0.546  -0.516  -0.269  -0.305  -0.262  -0.564  -0.586  -0.543
316   D        -0.527  -0.470  -0.506  -0.529  -0.441  -0.502  -0.564  -0.494  -0.530
317   S         0.274   0.228   0.209   0.250   0.182   0.156   0.130   0.059   0.021
318   T        -0.527  -0.502  -0.511  -0.563  -0.516  -0.564  -0.564  -0.532  -0.536
319   K        -1.109  -1.105  -1.048  -1.250  -1.245  -1.159  -0.911  -0.905  -0.831
320   L        -0.527  -0.547  -0.502  -0.771  -0.779  -0.712  -0.564  -0.586  -0.525
321   G         0.087   0.089   0.079   0.043   0.046   0.027  -0.152  -0.149  -0.174
322   P        -0.640  -0.639  -0.578  -0.388  -0.384  -0.289  -0.694  -0.690  -0.612
323   N         0.274   0.284   0.190   0.278   0.293   0.130   0.130   0.144  -0.007
324   Q         0.856   0.866   0.910   0.896   0.911   0.982   0.477   0.491   0.541
325   F        -0.527  -0.519  -0.529  -0.670  -0.643  -0.724  -0.564  -0.555  -0.557
326   E        -0.339  -0.319  -0.427  -0.106  -0.078  -0.211  -0.333  -0.306  -0.436
327   S         0.146   0.162   0.143   0.111   0.135   0.109  -0.092  -0.080  -0.097
328   I        -0.522  -0.522  -0.513  -0.962  -0.961  -0.940  -0.574  -0.571  -0.545
329   F         0.933   0.892   0.930   0.960   0.878   0.935   0.631   0.543   0.582
330   K        -0.339  -0.392  -0.412  -0.071  -0.150  -0.182  -0.333  -0.399  -0.417
331   K        -0.339  -0.385  -0.406  -0.109  -0.169  -0.191  -0.333  -0.392  -0.410
332   I         0.146   0.166   0.129  -0.047  -0.012  -0.118  -0.092  -0.066  -0.112
333   R        -1.006  -0.994  -0.970  -1.190  -1.187  -1.123  -0.815  -0.801  -0.758
334   L        -1.006  -0.994  -0.970  -0.834  -0.812  -0.785  -0.815  -0.801  -0.758
335   L        -1.006  -1.024  -1.005  -1.234  -1.250  -1.198  -0.815  -0.830  -0.792
336   L        -0.339  -0.364  -0.393  -0.496  -0.530  -0.548  -0.333  -0.364  -0.394
337   H        -1.109  -1.103  -1.048  -0.754  -0.754  -0.658  -0.911  -0.904  -0.831
338   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   N        -1.491  -1.485  -1.432  -1.442  -1.423  -1.353  -1.056  -1.048  -0.978
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12106
Output conservation file - output/Q12106
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
