1     M         0.844   0.845   0.893   0.984   0.987   1.044   0.893   0.896   0.964
2     S        -1.232  -1.204  -1.030  -1.414  -1.368  -1.115  -1.426  -1.393  -1.145
3     -        -0.116  -0.122  -0.288  -0.197  -0.204  -0.475  -0.238  -0.248  -0.558
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     F         0.057   0.002  -0.243   0.256   0.182  -0.266   0.028  -0.054  -0.479
7     D        -0.304  -0.328  -0.298  -0.430  -0.466  -0.420  -0.549  -0.592  -0.577
8     R         0.844   0.845   0.893   0.872   0.872   0.946   0.893   0.896   0.964
9     E        -1.025  -1.012  -0.999  -1.193  -1.176  -1.123  -1.205  -1.196  -1.110
10    E        -2.812  -2.810  -2.516  -2.639  -2.635  -2.221  -2.089  -2.085  -1.751
11    D         0.121   0.078  -0.227   0.158   0.110  -0.303   0.120   0.057  -0.451
12    Q        -2.480  -2.486  -2.248  -2.274  -2.292  -1.998  -1.978  -1.979  -1.677
13    K        -1.025  -1.034  -0.999  -1.144  -1.143  -1.042  -1.205  -1.203  -1.109
14    L        -0.567  -0.586  -0.953  -0.537  -0.564  -1.147  -0.543  -0.568  -1.046
15    K        -1.025  -1.013  -1.009  -1.141  -1.137  -1.081  -1.205  -1.198  -1.120
16    F         0.121   0.078  -0.227   0.346   0.290  -0.224   0.120   0.057  -0.451
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    K        -0.567  -0.586  -0.953  -0.473  -0.499  -1.047  -0.543  -0.568  -1.046
20    T        -0.425  -0.405  -0.313  -0.653  -0.615  -0.482  -0.763  -0.728  -0.604
21    S        -0.235  -0.178  -0.268  -0.297  -0.208  -0.389  -0.432  -0.339  -0.524
22    K         0.121   0.078  -0.227   0.150   0.097  -0.343   0.120   0.057  -0.451
23    K        -2.022  -1.955  -1.917  -1.975  -1.893  -1.782  -1.757  -1.701  -1.563
24    L        -1.232  -1.204  -1.030  -1.616  -1.569  -1.289  -1.426  -1.393  -1.145
25    K        -1.215  -1.217  -1.487  -1.066  -1.066  -1.477  -1.095  -1.098  -1.363
26    V        -0.567  -0.633  -0.950  -0.500  -0.585  -1.070  -0.543  -0.628  -1.043
27    S        -1.564  -1.571  -1.519  -1.427  -1.448  -1.397  -1.536  -1.538  -1.397
28    S        -1.690  -1.664  -1.521  -1.590  -1.562  -1.356  -1.647  -1.623  -1.398
29    T         0.121   0.078  -0.227   0.185   0.133  -0.325   0.120   0.057  -0.451
30    F         0.844   0.845   0.893   0.982   0.984   1.043   0.893   0.896   0.964
31    E         0.844   0.845   0.893   0.871   0.873   0.945   0.893   0.896   0.964
32    S         0.121   0.078  -0.227   0.223   0.167  -0.284   0.120   0.057  -0.451
33    M         0.844   0.845   0.893   0.984   0.987   1.044   0.893   0.896   0.964
34    N        -0.883  -0.867  -0.986  -0.779  -0.762  -0.995  -0.984  -0.969  -1.092
35    L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
36    K         0.844   0.845   0.893   0.767   0.769   0.853   0.893   0.896   0.964
37    D        -1.690  -1.645  -1.522  -1.665  -1.600  -1.425  -1.647  -1.607  -1.399
38    D        -0.567  -0.571  -0.947  -0.471  -0.474  -1.018  -0.543  -0.549  -1.038
39    L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
40    L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
41    R        -0.235  -0.178  -0.268  -0.288  -0.195  -0.390  -0.432  -0.339  -0.524
42    G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
43    I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
44    Y         0.844   0.845   0.893   1.006   1.008   1.064   0.893   0.896   0.964
45    S        -1.483  -1.476  -1.511  -1.326  -1.320  -1.365  -1.426  -1.422  -1.387
46    Y         0.844   0.845   0.893   1.006   1.008   1.064   0.893   0.896   0.964
47    G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
48    F        -0.235  -0.246  -0.277  -0.096  -0.114  -0.202  -0.432  -0.452  -0.540
49    E         0.844   0.845   0.893   0.871   0.873   0.945   0.893   0.896   0.964
50    A        -1.483  -1.508  -1.499  -1.341  -1.376  -1.369  -1.426  -1.453  -1.377
51    P         0.844   0.845   0.893   1.036   1.037   1.090   0.893   0.896   0.964
52    S         0.844   0.845   0.893   0.840   0.839   0.917   0.893   0.896   0.964
53    S        -0.235  -0.254  -0.285  -0.228  -0.262  -0.359  -0.432  -0.466  -0.554
54    I        -0.235  -0.246  -0.277  -0.435  -0.453  -0.530  -0.432  -0.452  -0.540
55    Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
56    S         0.844   0.845   0.893   0.840   0.839   0.917   0.893   0.896   0.964
57    R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
58    A         0.844   0.845   0.893   0.900   0.902   0.970   0.893   0.896   0.964
59    I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
60    T        -2.022  -2.039  -1.908  -1.927  -1.952  -1.804  -1.757  -1.765  -1.556
61    Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
62    I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
63    I        -0.235  -0.246  -0.277  -0.319  -0.333  -0.357  -0.432  -0.452  -0.540
64    S        -0.425  -0.424  -0.312  -0.661  -0.663  -0.496  -0.763  -0.762  -0.601
65    G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
66    K        -0.486  -0.481  -0.323  -0.780  -0.772  -0.511  -0.874  -0.866  -0.622
67    D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
68    V        -0.486  -0.477  -0.321  -0.837  -0.821  -0.559  -0.874  -0.859  -0.619
69    I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
70    A         0.844   0.845   0.893   0.900   0.902   0.970   0.893   0.896   0.964
71    Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
72    A         0.844   0.845   0.893   0.900   0.902   0.970   0.893   0.896   0.964
73    Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
74    S         0.844   0.845   0.893   0.840   0.839   0.917   0.893   0.896   0.964
75    G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
76    T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
77    G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
78    K         0.844   0.845   0.893   0.767   0.769   0.853   0.893   0.896   0.964
79    T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
80    A         0.844   0.845   0.893   0.900   0.902   0.970   0.893   0.896   0.964
81    T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
82    F         0.844   0.845   0.893   0.982   0.984   1.043   0.893   0.896   0.964
83    T        -0.425  -0.438  -0.316  -0.641  -0.670  -0.483  -0.763  -0.789  -0.609
84    I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
85    G        -0.235  -0.210  -0.280  -0.258  -0.219  -0.372  -0.432  -0.392  -0.544
86    L        -0.883  -0.935  -0.986  -0.791  -0.874  -1.032  -0.984  -1.050  -1.090
87    L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
88    Q        -0.425  -0.390  -0.308  -0.574  -0.510  -0.404  -0.763  -0.703  -0.595
89    A        -1.025  -1.060  -1.010  -1.171  -1.212  -1.105  -1.205  -1.243  -1.122
90    I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
91    D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
92    L        -1.025  -1.066  -1.005  -1.224  -1.282  -1.156  -1.205  -1.249  -1.116
93    R        -1.215  -1.216  -1.476  -1.051  -1.055  -1.432  -1.095  -1.096  -1.352
94    K        -1.690  -1.682  -1.525  -1.763  -1.761  -1.471  -1.647  -1.640  -1.402
95    K        -1.025  -1.042  -1.005  -1.124  -1.140  -1.004  -1.205  -1.222  -1.116
96    D        -0.486  -0.481  -0.323  -0.779  -0.769  -0.510  -0.874  -0.866  -0.622
97    L        -1.232  -1.204  -1.030  -1.396  -1.367  -1.065  -1.426  -1.393  -1.145
98    Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
99    A         0.844   0.845   0.893   0.900   0.902   0.970   0.893   0.896   0.964
100   L         0.121   0.140  -0.226   0.134   0.155  -0.320   0.120   0.146  -0.449
101   I        -0.486  -0.480  -0.323  -0.903  -0.891  -0.618  -0.874  -0.865  -0.622
102   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
103   S         0.844   0.845   0.893   0.840   0.839   0.917   0.893   0.896   0.964
104   P         0.844   0.845   0.893   1.036   1.037   1.090   0.893   0.896   0.964
105   T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
106   R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
107   E         0.844   0.845   0.893   0.871   0.873   0.945   0.893   0.896   0.964
108   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
109   A         0.844   0.845   0.893   0.900   0.902   0.970   0.893   0.896   0.964
110   S        -2.480  -2.462  -2.245  -2.394  -2.371  -2.073  -1.978  -1.963  -1.675
111   Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
112   I         0.121   0.067  -0.231   0.097   0.030  -0.402   0.120   0.042  -0.458
113   G        -0.883  -0.931  -0.999  -0.815  -0.880  -1.006  -0.984  -1.042  -1.107
114   Q        -1.483  -1.492  -1.498  -1.370  -1.389  -1.403  -1.426  -1.437  -1.376
115   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
116   V        -0.235  -0.255  -0.301  -0.418  -0.452  -0.571  -0.432  -0.467  -0.582
117   K        -2.022  -2.055  -1.912  -2.010  -2.065  -1.820  -1.757  -1.785  -1.559
118   N        -1.232  -1.204  -1.030  -1.186  -1.151  -0.891  -1.426  -1.393  -1.145
119   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
120   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
121   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
122   Y         0.121   0.078  -0.227   0.419   0.369  -0.066   0.120   0.057  -0.451
123   M         0.121   0.067  -0.231   0.348   0.279  -0.231   0.120   0.042  -0.458
124   N         0.844   0.845   0.893   0.964   0.966   1.027   0.893   0.896   0.964
125   V         0.121   0.152  -0.222   0.106   0.146  -0.416   0.120   0.164  -0.442
126   N        -2.022  -2.032  -1.919  -1.750  -1.770  -1.638  -1.757  -1.759  -1.564
127   A        -1.232  -1.204  -1.030  -1.224  -1.177  -0.950  -1.426  -1.393  -1.145
128   F        -0.567  -0.575  -0.954  -0.103  -0.112  -0.684  -0.543  -0.553  -1.048
129   A         0.844   0.845   0.893   0.900   0.902   0.970   0.893   0.896   0.964
130   I        -0.567  -0.575  -0.954  -0.143  -0.152  -0.786  -0.543  -0.553  -1.048
131   T        -0.425  -0.438  -0.316  -0.748  -0.773  -0.569  -0.763  -0.789  -0.609
132   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
133   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
134   K        -0.486  -0.480  -0.323  -0.821  -0.811  -0.546  -0.874  -0.865  -0.621
135   T        -2.148  -2.133  -1.922  -1.968  -1.962  -1.619  -1.868  -1.855  -1.567
136   L        -1.025  -1.044  -1.006  -1.244  -1.267  -1.135  -1.205  -1.225  -1.117
137   K        -1.483  -1.510  -1.514  -1.417  -1.458  -1.479  -1.426  -1.454  -1.391
138   D        -2.022  -2.063  -1.916  -1.920  -1.976  -1.770  -1.757  -1.791  -1.562
139   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
140   L        -1.483  -1.450  -1.497  -1.567  -1.525  -1.559  -1.426  -1.394  -1.374
141   K         0.121   0.145  -0.223   0.149   0.178  -0.342   0.120   0.154  -0.445
142   K         0.844   0.845   0.893   0.767   0.769   0.853   0.893   0.896   0.964
143   M        -1.215  -1.267  -1.496  -1.114  -1.193  -1.547  -1.095  -1.155  -1.373
144   Q        -1.483  -1.514  -1.509  -1.415  -1.465  -1.470  -1.426  -1.460  -1.386
145   K        -1.690  -1.657  -1.530  -1.676  -1.630  -1.418  -1.647  -1.613  -1.406
146   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   G         0.121   0.067  -0.231   0.265   0.200  -0.230   0.120   0.042  -0.458
148   C        -0.425  -0.438  -0.316  -0.458  -0.477  -0.293  -0.763  -0.789  -0.609
149   Q        -0.235  -0.246  -0.277  -0.171  -0.186  -0.243  -0.432  -0.452  -0.540
150   A        -1.025  -0.986  -0.994  -1.273  -1.204  -1.159  -1.205  -1.153  -1.103
151   V         0.121   0.094  -0.228   0.106   0.072  -0.427   0.120   0.080  -0.453
152   S         0.844   0.845   0.893   0.840   0.839   0.917   0.893   0.896   0.964
153   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
154   T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
155   P         0.844   0.845   0.893   1.036   1.037   1.090   0.893   0.896   0.964
156   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
157   R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
158   V         0.121   0.140  -0.226   0.161   0.183  -0.267   0.120   0.146  -0.449
159   L        -1.815  -1.760  -1.892  -1.726  -1.646  -1.885  -1.536  -1.482  -1.542
160   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
161   M         0.121   0.152  -0.222   0.349   0.390  -0.209   0.120   0.164  -0.442
162   I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
163   K        -0.235  -0.246  -0.277  -0.349  -0.368  -0.435  -0.432  -0.452  -0.540
164   K        -0.235  -0.212  -0.296  -0.288  -0.251  -0.446  -0.432  -0.396  -0.573
165   Q        -0.883  -0.884  -0.987  -0.827  -0.835  -0.994  -0.984  -0.993  -1.091
166   M        -2.355  -2.364  -2.236  -1.874  -1.904  -1.756  -1.868  -1.875  -1.669
167   L         0.121   0.094  -0.228   0.095   0.059  -0.435   0.120   0.080  -0.453
168   Q        -2.022  -2.017  -1.914  -1.823  -1.811  -1.659  -1.757  -1.749  -1.561
169   T         0.121   0.067  -0.231   0.171   0.104  -0.371   0.120   0.042  -0.458
170   R         0.121   0.140  -0.226   0.230   0.253  -0.307   0.120   0.146  -0.449
171   N        -0.235  -0.237  -0.301  -0.088  -0.091  -0.214  -0.432  -0.436  -0.581
172   V        -1.564  -1.577  -1.509  -1.696  -1.696  -1.532  -1.536  -1.544  -1.387
173   Q        -0.235  -0.239  -0.281  -0.344  -0.351  -0.433  -0.432  -0.440  -0.546
174   M        -0.883  -0.894  -0.986  -0.792  -0.829  -1.030  -0.984  -1.012  -1.090
175   L         0.121   0.187  -0.221   0.134   0.209  -0.313   0.120   0.212  -0.441
176   V        -0.486  -0.480  -0.322  -0.903  -0.891  -0.616  -0.874  -0.865  -0.620
177   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
178   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
179   E         0.844   0.845   0.893   0.871   0.873   0.945   0.893   0.896   0.964
180   A         0.844   0.845   0.893   0.900   0.902   0.970   0.893   0.896   0.964
181   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
182   E         0.844   0.845   0.893   0.871   0.873   0.945   0.893   0.896   0.964
183   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
184   L        -0.567  -0.478  -0.948  -0.451  -0.346  -0.933  -0.543  -0.429  -1.039
185   S        -1.690  -1.696  -1.531  -1.656  -1.653  -1.436  -1.647  -1.646  -1.407
186   E        -1.690  -1.711  -1.530  -1.783  -1.812  -1.541  -1.647  -1.666  -1.406
187   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
190   F         0.844   0.845   0.893   0.982   0.984   1.043   0.893   0.896   0.964
191   K        -0.567  -0.529  -0.946  -0.458  -0.409  -0.999  -0.543  -0.494  -1.037
192   Q        -0.883  -0.922  -1.000  -0.776  -0.830  -0.919  -0.984  -1.035  -1.108
193   Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
194   I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
195   Y         0.844   0.845   0.893   1.006   1.008   1.064   0.893   0.896   0.964
196   D        -0.235  -0.178  -0.268  -0.354  -0.264  -0.421  -0.432  -0.339  -0.524
197   I         0.121   0.145  -0.223   0.084   0.115  -0.429   0.120   0.154  -0.445
198   F        -0.425  -0.438  -0.316  -0.403  -0.429  -0.267  -0.763  -0.789  -0.609
199   A        -1.483  -1.473  -1.512  -1.417  -1.419  -1.481  -1.426  -1.426  -1.389
200   K        -1.025  -1.008  -1.009  -0.986  -0.981  -0.911  -1.205  -1.193  -1.120
201   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
202   P         0.844   0.845   0.893   1.036   1.037   1.090   0.893   0.896   0.964
203   K        -1.215  -1.208  -1.480  -0.802  -0.793  -1.283  -1.095  -1.086  -1.356
204   N        -2.148  -2.120  -1.921  -2.044  -2.012  -1.709  -1.868  -1.845  -1.566
205   C        -2.022  -2.032  -1.919  -1.963  -1.971  -1.787  -1.757  -1.759  -1.564
206   Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
207   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
208   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
209   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
210   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
211   S         0.844   0.845   0.893   0.840   0.839   0.917   0.893   0.896   0.964
212   A         0.844   0.845   0.893   0.900   0.902   0.970   0.893   0.896   0.964
213   T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
214   M        -0.425  -0.438  -0.316  -0.638  -0.658  -0.451  -0.763  -0.789  -0.609
215   N        -1.025  -1.011  -1.004  -0.945  -0.934  -0.904  -1.205  -1.192  -1.115
216   K        -2.480  -2.481  -2.247  -2.149  -2.151  -1.781  -1.978  -1.975  -1.676
217   D        -1.025  -0.998  -0.999  -1.177  -1.137  -1.096  -1.205  -1.171  -1.108
218   I        -0.425  -0.438  -0.316  -0.773  -0.801  -0.602  -0.763  -0.789  -0.609
219   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
220   E         0.121   0.145  -0.223   0.239   0.269  -0.298   0.120   0.154  -0.445
221   V        -1.151  -1.145  -1.027  -1.237  -1.232  -1.124  -1.316  -1.310  -1.141
222   T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
223   R        -2.480  -2.446  -2.241  -2.331  -2.287  -1.982  -1.978  -1.952  -1.673
224   K         0.844   0.845   0.893   0.767   0.769   0.853   0.893   0.896   0.964
225   F         0.844   0.845   0.893   0.982   0.984   1.043   0.893   0.896   0.964
226   M        -0.425  -0.410  -0.311  -0.513  -0.481  -0.368  -0.763  -0.737  -0.599
227   N        -0.883  -0.931  -0.999  -0.851  -0.914  -1.019  -0.984  -1.042  -1.107
228   D         0.121   0.078  -0.227   0.155   0.107  -0.311   0.120   0.057  -0.451
229   P         0.844   0.845   0.893   1.036   1.037   1.090   0.893   0.896   0.964
230   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
231   K        -0.425  -0.424  -0.312  -0.676  -0.674  -0.495  -0.763  -0.762  -0.601
232   I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
233   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
234   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
235   K         0.844   0.845   0.893   0.767   0.769   0.853   0.893   0.896   0.964
236   R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
237   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
238   E         0.121   0.187  -0.221   0.239   0.319  -0.293   0.120   0.212  -0.441
239   I        -0.425  -0.424  -0.312  -0.787  -0.787  -0.603  -0.763  -0.762  -0.601
240   S        -0.425  -0.424  -0.317  -0.653  -0.652  -0.489  -0.763  -0.764  -0.611
241   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
242   E        -0.567  -0.589  -0.948  -0.377  -0.410  -0.979  -0.543  -0.573  -1.040
243   G         0.121   0.067  -0.231   0.233   0.165  -0.321   0.120   0.042  -0.458
244   I        -0.425  -0.424  -0.312  -0.787  -0.787  -0.603  -0.763  -0.762  -0.601
245   K         0.844   0.845   0.893   0.767   0.769   0.853   0.893   0.896   0.964
246   Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
247   Y         0.844   0.845   0.893   1.006   1.008   1.064   0.893   0.896   0.964
248   V        -1.564  -1.510  -1.511  -1.321  -1.260  -1.244  -1.536  -1.489  -1.388
249   V        -0.486  -0.480  -0.323  -0.903  -0.891  -0.617  -0.874  -0.865  -0.621
250   N        -1.690  -1.696  -1.531  -1.634  -1.636  -1.423  -1.647  -1.646  -1.407
251   V        -0.235  -0.178  -0.268  -0.294  -0.214  -0.326  -0.432  -0.339  -0.524
252   D         0.121   0.141  -0.225   0.239   0.264  -0.300   0.120   0.148  -0.447
253   K        -0.567  -0.522  -0.944  -0.458  -0.401  -0.995  -0.543  -0.485  -1.035
254   E         0.844   0.845   0.893   0.871   0.873   0.945   0.893   0.896   0.964
255   E        -0.425  -0.388  -0.307  -0.638  -0.564  -0.468  -0.763  -0.699  -0.594
256   W         0.844   0.845   0.893   1.121   1.122   1.165   0.893   0.896   0.964
257   K         0.844   0.845   0.893   0.767   0.769   0.853   0.893   0.896   0.964
258   F         0.844   0.845   0.893   0.982   0.984   1.043   0.893   0.896   0.964
259   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
260   T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
261   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
262   C         0.844   0.845   0.893   1.090   1.092   1.138   0.893   0.896   0.964
263   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
264   I        -0.235  -0.239  -0.281  -0.428  -0.437  -0.537  -0.432  -0.440  -0.546
265   Y         0.844   0.845   0.893   1.006   1.008   1.064   0.893   0.896   0.964
266   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
267   S        -1.025  -1.001  -1.004  -1.125  -1.098  -1.036  -1.205  -1.180  -1.114
268   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
269   T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
270   I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
271   T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
272   Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
273   C        -0.425  -0.438  -0.316  -0.438  -0.459  -0.277  -0.763  -0.789  -0.609
274   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
275   I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
276   F         0.844   0.845   0.893   0.982   0.984   1.043   0.893   0.896   0.964
277   C         0.844   0.845   0.893   1.090   1.092   1.138   0.893   0.896   0.964
278   N         0.844   0.845   0.893   0.964   0.966   1.027   0.893   0.896   0.964
279   T        -0.235  -0.273  -0.303  -0.319  -0.382  -0.463  -0.432  -0.498  -0.586
280   K        -0.425  -0.441  -0.319  -0.676  -0.706  -0.506  -0.763  -0.794  -0.614
281   K        -1.483  -1.420  -1.502  -1.522  -1.437  -1.576  -1.426  -1.366  -1.379
282   K         0.844   0.845   0.893   0.767   0.769   0.853   0.893   0.896   0.964
283   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
284   D        -0.235  -0.178  -0.268  -0.324  -0.236  -0.377  -0.432  -0.339  -0.524
285   W         0.844   0.845   0.893   1.121   1.122   1.165   0.893   0.896   0.964
286   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
287   S        -1.151  -1.160  -1.027  -1.274  -1.290  -1.094  -1.316  -1.328  -1.141
288   Q        -2.022  -2.079  -1.912  -1.883  -1.947  -1.677  -1.757  -1.801  -1.559
289   R        -1.025  -0.988  -0.997  -1.163  -1.106  -1.077  -1.205  -1.155  -1.106
290   L        -0.425  -0.438  -0.316  -0.550  -0.583  -0.422  -0.763  -0.789  -0.609
291   I        -1.483  -1.513  -1.503  -1.511  -1.557  -1.558  -1.426  -1.458  -1.379
292   Q        -1.690  -1.657  -1.530  -1.755  -1.698  -1.534  -1.647  -1.613  -1.406
293   S        -2.022  -2.024  -1.915  -1.836  -1.845  -1.689  -1.757  -1.758  -1.561
294   N         0.844   0.845   0.893   0.964   0.966   1.027   0.893   0.896   0.964
295   F         0.844   0.845   0.893   0.982   0.984   1.043   0.893   0.896   0.964
296   A        -0.883  -0.931  -0.999  -0.876  -0.940  -1.051  -0.984  -1.042  -1.107
297   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
298   V        -2.022  -2.054  -1.908  -1.971  -2.021  -1.777  -1.757  -1.784  -1.556
299   S        -0.235  -0.178  -0.268  -0.266  -0.182  -0.345  -0.432  -0.339  -0.524
300   M         0.844   0.845   0.893   0.984   0.987   1.044   0.893   0.896   0.964
301   H         0.844   0.845   0.893   1.086   1.088   1.134   0.893   0.896   0.964
302   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
303   D         0.121   0.078  -0.227   0.142   0.091  -0.350   0.120   0.057  -0.451
304   M         0.844   0.845   0.893   0.984   0.987   1.044   0.893   0.896   0.964
305   K        -0.883  -0.877  -0.990  -0.848  -0.844  -0.974  -0.984  -0.982  -1.095
306   Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
307   E        -1.232  -1.233  -1.031  -1.511  -1.509  -1.184  -1.426  -1.426  -1.146
308   E         0.121   0.140  -0.226   0.239   0.261  -0.303   0.120   0.146  -0.449
309   R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
310   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
311   K        -1.815  -1.889  -1.904  -1.564  -1.673  -1.738  -1.536  -1.609  -1.552
312   V        -0.425  -0.438  -0.316  -0.782  -0.809  -0.605  -0.763  -0.789  -0.609
313   M         0.844   0.845   0.893   0.984   0.987   1.044   0.893   0.896   0.964
314   N        -0.235  -0.246  -0.277  -0.154  -0.173  -0.277  -0.432  -0.452  -0.540
315   D        -0.235  -0.240  -0.300  -0.354  -0.360  -0.475  -0.432  -0.442  -0.580
316   F         0.844   0.845   0.893   0.982   0.984   1.043   0.893   0.896   0.964
317   R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
318   T        -1.690  -1.680  -1.523  -1.743  -1.734  -1.484  -1.647  -1.640  -1.400
319   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
320   H        -1.815  -1.846  -1.905  -1.401  -1.454  -1.592  -1.536  -1.568  -1.553
321   S         0.121   0.067  -0.231   0.227   0.158  -0.280   0.120   0.042  -0.458
322   R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
323   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
324   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
325   I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
326   S         0.121   0.078  -0.227   0.255   0.203  -0.194   0.120   0.057  -0.451
327   T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
328   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
329   V         0.121   0.078  -0.227   0.106   0.051  -0.425   0.120   0.057  -0.451
330   W         0.844   0.845   0.893   1.121   1.122   1.165   0.893   0.896   0.964
331   A         0.844   0.845   0.893   0.900   0.902   0.970   0.893   0.896   0.964
332   R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
333   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
334   I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
335   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
336   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
337   Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
338   Q         0.844   0.845   0.893   0.876   0.879   0.949   0.893   0.896   0.964
339   V         0.121   0.067  -0.231   0.106   0.037  -0.433   0.120   0.042  -0.458
340   S         0.844   0.845   0.893   0.840   0.839   0.917   0.893   0.896   0.964
341   L         0.844   0.845   0.893   0.734   0.735   0.824   0.893   0.896   0.964
342   V         0.844   0.845   0.893   0.745   0.748   0.833   0.893   0.896   0.964
343   I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
344   N         0.844   0.845   0.893   0.964   0.966   1.027   0.893   0.896   0.964
345   Y         0.844   0.845   0.893   1.006   1.008   1.064   0.893   0.896   0.964
346   D         0.844   0.845   0.893   0.758   0.763   0.845   0.893   0.896   0.964
347   L         0.121   0.067  -0.231   0.095   0.024  -0.441   0.120   0.042  -0.458
348   P         0.844   0.845   0.893   1.036   1.037   1.090   0.893   0.896   0.964
349   E        -2.480  -2.490  -2.247  -2.271  -2.285  -1.939  -1.978  -1.981  -1.677
350   I        -1.151  -1.115  -1.010  -1.248  -1.182  -1.087  -1.316  -1.269  -1.120
351   I        -2.022  -2.032  -1.919  -2.017  -2.023  -1.915  -1.757  -1.759  -1.564
352   E         0.844   0.845   0.893   0.871   0.873   0.945   0.893   0.896   0.964
353   N         0.844   0.845   0.893   0.964   0.966   1.027   0.893   0.896   0.964
354   Y         0.844   0.845   0.893   1.006   1.008   1.064   0.893   0.896   0.964
355   I        -0.235  -0.214  -0.294  -0.435  -0.400  -0.562  -0.432  -0.398  -0.569
356   H         0.844   0.845   0.893   1.086   1.088   1.134   0.893   0.896   0.964
357   R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
358   I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
359   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
360   R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
361   S         0.844   0.845   0.893   0.840   0.839   0.917   0.893   0.896   0.964
362   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
363   R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
364   F         0.844   0.845   0.893   0.982   0.984   1.043   0.893   0.896   0.964
365   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
366   R         0.844   0.845   0.893   0.861   0.864   0.936   0.893   0.896   0.964
367   K         0.844   0.845   0.893   0.767   0.769   0.853   0.893   0.896   0.964
368   G         0.844   0.845   0.893   0.868   0.871   0.942   0.893   0.896   0.964
369   V         0.121   0.152  -0.222   0.118   0.158  -0.380   0.120   0.164  -0.442
370   A         0.844   0.845   0.893   0.900   0.902   0.970   0.893   0.896   0.964
371   I         0.844   0.845   0.893   0.719   0.722   0.811   0.893   0.896   0.964
372   N         0.844   0.845   0.893   0.964   0.966   1.027   0.893   0.896   0.964
373   F        -0.235  -0.178  -0.268  -0.181  -0.087  -0.310  -0.432  -0.339  -0.524
374   I        -1.564  -1.565  -1.510  -1.747  -1.747  -1.616  -1.536  -1.535  -1.388
375   T         0.844   0.845   0.893   0.806   0.810   0.887   0.893   0.896   0.964
376   K        -0.883  -0.875  -0.994  -0.888  -0.882  -1.036  -0.984  -0.980  -1.100
377   A        -1.483  -1.470  -1.498  -1.440  -1.415  -1.494  -1.426  -1.407  -1.376
378   D         0.121   0.067  -0.231   0.142   0.078  -0.357   0.120   0.042  -0.458
379   L        -1.815  -1.846  -1.905  -1.704  -1.747  -1.878  -1.536  -1.568  -1.553
380   A        -2.812  -2.786  -2.520  -2.538  -2.485  -2.160  -2.089  -2.069  -1.754
381   K        -2.148  -2.124  -1.923  -2.241  -2.213  -1.877  -1.868  -1.849  -1.568
382   L         0.121   0.094  -0.228   0.134   0.101  -0.324   0.120   0.080  -0.453
383   R        -0.425  -0.436  -0.319  -0.642  -0.667  -0.496  -0.763  -0.785  -0.613
384   E        -0.486  -0.480  -0.323  -0.779  -0.765  -0.506  -0.874  -0.865  -0.621
385   I         0.121   0.152  -0.222   0.119   0.156  -0.328   0.120   0.164  -0.442
386   E         0.844   0.845   0.893   0.871   0.873   0.945   0.893   0.896   0.964
387   K        -2.022  -2.004  -1.909  -1.985  -1.964  -1.823  -1.757  -1.743  -1.557
388   F        -0.883  -0.887  -0.986  -0.613  -0.602  -0.766  -0.984  -0.976  -1.092
389   Y         0.844   0.845   0.893   1.006   1.008   1.064   0.893   0.896   0.964
390   S        -0.883  -0.902  -0.988  -0.872  -0.901  -1.059  -0.984  -1.006  -1.095
391   I        -0.486  -0.481  -0.323  -0.857  -0.847  -0.579  -0.874  -0.866  -0.622
392   K        -1.483  -1.450  -1.504  -1.485  -1.441  -1.518  -1.426  -1.390  -1.381
393   I         0.121   0.094  -0.228   0.084   0.050  -0.437   0.120   0.080  -0.453
394   N        -1.025  -1.009  -1.004  -1.215  -1.194  -1.108  -1.205  -1.188  -1.114
395   P        -0.425  -0.438  -0.316  -0.491  -0.514  -0.328  -0.763  -0.789  -0.609
396   M         0.121   0.067  -0.231   0.357   0.290  -0.202   0.120   0.042  -0.458
397   P         0.844   0.845   0.893   1.036   1.037   1.090   0.893   0.896   0.964
398   A        -1.232  -1.207  -1.033  -1.322  -1.277  -1.048  -1.426  -1.397  -1.149
399   N         0.121   0.094  -0.228   0.331   0.297  -0.231   0.120   0.080  -0.453
400   F        -1.690  -1.692  -1.526  -1.898  -1.913  -1.607  -1.647  -1.652  -1.403
401   A        -2.480  -2.508  -2.239  -2.198  -2.241  -1.902  -1.978  -1.993  -1.672
402   E        -0.425  -0.438  -0.316  -0.678  -0.700  -0.502  -0.763  -0.789  -0.609
403   L        -1.151  -1.122  -1.012  -1.351  -1.298  -1.130  -1.316  -1.278  -1.122
404   S        -1.564  -1.568  -1.520  -1.521  -1.532  -1.492  -1.536  -1.536  -1.397
405   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12099
Output conservation file - output/Q12099
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
