1     M         1.945   1.968   2.035   2.219   2.252   2.358   2.189   2.222   2.326
2     D        -1.133  -1.153  -1.114  -1.174  -1.171  -1.133  -0.940  -0.955  -0.889
3     R        -0.789  -0.768  -0.707  -0.892  -0.864  -0.765  -0.829  -0.801  -0.717
4     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     K        -0.106  -0.135  -0.094  -0.089  -0.140  -0.064  -0.326  -0.370  -0.317
10    R         0.071   0.083  -0.024   0.212   0.229   0.051  -0.064  -0.045  -0.213
11    I         1.945   1.968   2.035   1.800   1.833   1.938   2.189   2.222   2.326
12    V        -0.136  -0.129  -0.104  -0.462  -0.455  -0.425  -0.386  -0.374  -0.335
13    I         0.071   0.064   0.009  -0.153  -0.167  -0.273  -0.064  -0.073  -0.165
14    S         0.071   0.081   0.001  -0.129  -0.115  -0.249  -0.064  -0.047  -0.177
15    I         0.958   0.955   0.859   0.763   0.754   0.573   0.901   0.891   0.686
16    G         0.958   0.955   0.862   1.082   1.079   0.928   0.901   0.891   0.690
17    G         1.945   1.968   2.035   2.048   2.083   2.187   2.189   2.222   2.326
18    G         1.945   1.968   2.035   2.048   2.083   2.187   2.189   2.222   2.326
19    H         1.945   1.968   2.035   2.232   2.268   2.371   2.189   2.222   2.326
20    A         0.071   0.064  -0.001   0.151   0.140   0.009  -0.064  -0.073  -0.179
21    T        -0.136  -0.137  -0.091  -0.142  -0.144  -0.077  -0.386  -0.383  -0.318
22    G         1.945   1.968   2.035   2.048   2.083   2.187   2.189   2.222   2.326
23    V        -0.050  -0.004  -0.024  -0.139  -0.077  -0.081  -0.270  -0.204  -0.221
24    G         0.234   0.327   0.120   0.262   0.405   0.069   0.177   0.316   0.001
25    A        -1.133  -1.131  -1.123  -0.907  -0.924  -0.903  -0.940  -0.934  -0.898
26    I        -0.506  -0.533  -0.588  -0.268  -0.325  -0.413  -0.493  -0.530  -0.581
27    A        -0.506  -0.549  -0.580  -0.240  -0.288  -0.342  -0.493  -0.549  -0.572
28    L        -0.222  -0.206  -0.138  -0.577  -0.542  -0.449  -0.493  -0.469  -0.379
29    D        -1.133  -1.143  -1.107  -1.244  -1.251  -1.221  -0.940  -0.946  -0.882
30    L         0.234   0.144   0.079   0.092  -0.052  -0.162   0.177   0.038  -0.060
31    Q        -0.050  -0.028  -0.051  -0.158  -0.153  -0.149  -0.270  -0.254  -0.266
32    N        -0.506  -0.405  -0.567  -0.428  -0.279  -0.524  -0.493  -0.362  -0.556
33    T        -0.678  -0.703  -0.662  -0.718  -0.762  -0.668  -0.717  -0.739  -0.671
34    F        -0.050  -0.116  -0.056  -0.277  -0.384  -0.285  -0.270  -0.344  -0.269
35    K        -1.589  -1.571  -1.509  -1.650  -1.593  -1.525  -1.164  -1.141  -1.055
36    S        -1.133  -1.153  -1.114  -1.004  -1.050  -0.960  -0.940  -0.955  -0.889
37    L        -0.050  -0.007  -0.033  -0.434  -0.357  -0.408  -0.270  -0.206  -0.241
38    Y        -1.133  -1.143  -1.107  -0.952  -0.976  -0.928  -0.940  -0.946  -0.882
39    N        -0.050  -0.028  -0.051  -0.043  -0.038  -0.060  -0.270  -0.254  -0.266
40    S        -1.133  -1.135  -1.087  -1.181  -1.230  -1.116  -0.940  -0.938  -0.864
41    I        -1.230  -1.214  -1.149  -1.119  -1.101  -0.992  -1.030  -1.008  -0.920
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    N        -0.050  -0.127  -0.047  -0.227  -0.340  -0.237  -0.270  -0.362  -0.261
45    I         0.578   0.597   0.665   0.244   0.283   0.384   0.177   0.207   0.301
46    R        -1.133  -1.152  -1.112  -0.913  -0.929  -0.874  -0.940  -0.953  -0.887
47    V        -0.050  -0.129  -0.064  -0.177  -0.283  -0.183  -0.270  -0.364  -0.279
48    I         1.945   1.968   2.035   1.851   1.901   1.989   2.189   2.222   2.326
49    N         0.234   0.164   0.076   0.261   0.168   0.043   0.177   0.066  -0.064
50    L        -0.050  -0.044  -0.047  -0.241  -0.214  -0.221  -0.270  -0.273  -0.260
51    D         0.690   0.646   0.699   0.438   0.359   0.432   0.401   0.306   0.369
52    N         0.071   0.115   0.012  -0.001   0.067  -0.095  -0.064   0.003  -0.160
53    M         0.071   0.115   0.012   0.241   0.305   0.141  -0.064   0.003  -0.160
54    I        -0.683  -0.615  -0.633  -0.701  -0.587  -0.617  -0.708  -0.621  -0.634
55    E         0.234   0.128   0.076   0.329   0.160   0.093   0.177   0.016  -0.064
56    G        -1.133  -1.131  -1.123  -1.029  -1.018  -0.977  -0.940  -0.934  -0.898
57    N        -1.133  -1.053  -1.089  -0.918  -0.791  -0.846  -0.940  -0.851  -0.865
58    I        -0.506  -0.569  -0.602  -0.481  -0.548  -0.608  -0.493  -0.571  -0.598
59    -        -0.106  -0.102  -0.062  -0.297  -0.303  -0.239  -0.326  -0.321  -0.270
60    -         0.836   0.834   0.823   0.946   0.938   0.898   0.680   0.670   0.615
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -0.106  -0.094  -0.070  -0.219  -0.193  -0.171  -0.326  -0.311  -0.281
65    K        -0.506  -0.549  -0.566  -0.393  -0.473  -0.508  -0.493  -0.549  -0.555
66    S        -0.678  -0.716  -0.648  -0.699  -0.772  -0.653  -0.717  -0.750  -0.656
67    Y         0.234   0.128   0.076   0.533   0.381   0.316   0.177   0.016  -0.064
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    N        -0.678  -0.633  -0.638  -0.864  -0.800  -0.799  -0.717  -0.663  -0.646
80    N        -0.506  -0.565  -0.571  -0.462  -0.562  -0.592  -0.493  -0.567  -0.561
81    N        -1.133  -1.144  -1.089  -1.172  -1.207  -1.116  -0.940  -0.946  -0.866
82    D         1.056   0.919   0.908   1.009   0.801   0.779   1.071   0.826   0.777
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    Y        -0.050  -0.129  -0.064  -0.024  -0.168  -0.070  -0.270  -0.364  -0.279
94    D        -0.506  -0.569  -0.602  -0.506  -0.614  -0.644  -0.493  -0.571  -0.598
95    F         1.945   1.968   2.035   2.160   2.196   2.299   2.189   2.222   2.326
96    D         0.234   0.144   0.079   0.183   0.035  -0.068   0.177   0.038  -0.060
97    N        -0.506  -0.405  -0.567  -0.466  -0.307  -0.572  -0.493  -0.362  -0.556
98    I        -0.050  -0.117  -0.050  -0.379  -0.444  -0.357  -0.270  -0.346  -0.261
99    L        -1.589  -1.571  -1.509  -1.573  -1.516  -1.448  -1.164  -1.141  -1.055
100   N        -0.678  -0.635  -0.646  -0.568  -0.496  -0.501  -0.717  -0.665  -0.654
101   L        -1.133  -1.060  -1.082  -0.969  -0.841  -0.893  -0.940  -0.859  -0.859
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   V         0.234   0.327   0.120   0.092   0.228  -0.094   0.177   0.316   0.001
109   Y        -1.133  -1.131  -1.123  -1.183  -1.193  -1.133  -0.940  -0.934  -0.898
110   E        -0.506  -0.409  -0.539  -0.371  -0.218  -0.425  -0.493  -0.367  -0.523
111   K        -1.589  -1.571  -1.509  -1.330  -1.290  -1.204  -1.164  -1.141  -1.055
112   H        -1.133  -1.143  -1.107  -1.073  -1.109  -1.028  -0.940  -0.946  -0.882
113   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   Q        -0.683  -0.625  -0.640  -0.782  -0.694  -0.713  -0.708  -0.633  -0.642
123   H        -0.136  -0.095  -0.088  -0.045   0.006   0.024  -0.386  -0.334  -0.313
124   D        -1.230  -1.214  -1.149  -1.119  -1.088  -0.992  -1.030  -1.008  -0.920
125   Y        -1.133  -1.133  -1.091  -1.036  -1.018  -0.965  -0.940  -0.937  -0.868
126   E        -0.678  -0.721  -0.650  -0.729  -0.776  -0.666  -0.717  -0.755  -0.658
127   D        -1.133  -1.143  -1.107  -1.103  -1.116  -1.082  -0.940  -0.946  -0.882
128   P        -1.133  -1.144  -1.089  -0.836  -0.825  -0.768  -0.940  -0.946  -0.866
129   I        -1.133  -1.131  -1.123  -1.015  -0.990  -1.037  -0.940  -0.934  -0.898
130   D        -0.678  -0.713  -0.668  -0.770  -0.798  -0.722  -0.717  -0.748  -0.677
131   L         0.234   0.164   0.076   0.146   0.047  -0.125   0.177   0.066  -0.064
132   I        -0.050  -0.129  -0.064  -0.395  -0.501  -0.410  -0.270  -0.364  -0.279
133   I         0.578   0.597   0.665   0.068   0.103   0.201   0.177   0.207   0.301
134   V         1.056   0.919   0.908   1.140   0.916   0.893   1.071   0.826   0.777
135   C        -0.050  -0.129  -0.064   0.201   0.064   0.167  -0.270  -0.364  -0.279
136   G         1.945   1.968   2.035   2.064   2.101   2.203   2.189   2.222   2.326
137   C        -0.050  -0.129  -0.064   0.017  -0.100  -0.008  -0.270  -0.364  -0.279
138   Y         1.945   1.968   2.035   2.104   2.138   2.243   2.189   2.222   2.326
139   A         1.056   1.108   0.952   1.213   1.288   1.055   1.071   1.154   0.860
140   L         1.945   1.968   2.035   1.779   1.810   1.917   2.189   2.222   2.326
141   Y         1.056   1.108   0.952   1.293   1.365   1.155   1.071   1.154   0.860
142   D         1.056   1.113   0.944   1.019   1.101   0.857   1.071   1.162   0.845
143   K        -0.506  -0.549  -0.580  -0.434  -0.519  -0.553  -0.493  -0.549  -0.572
144   R        -1.133  -1.143  -1.107  -1.088  -1.133  -1.045  -0.940  -0.946  -0.882
145   I        -0.050  -0.048  -0.042  -0.395  -0.411  -0.390  -0.270  -0.277  -0.255
146   N        -0.050   0.013  -0.042  -0.011   0.088   0.031  -0.270  -0.175  -0.249
147   E        -0.678  -0.721  -0.650  -0.829  -0.888  -0.773  -0.717  -0.755  -0.658
148   I         0.578   0.595   0.665   0.068   0.100   0.201   0.177   0.203   0.301
149   S         0.690   0.728   0.720   0.552   0.616   0.586   0.401   0.468   0.412
150   Q        -0.678  -0.623  -0.647  -0.550  -0.488  -0.504  -0.717  -0.655  -0.655
151   L        -0.050  -0.129  -0.064  -0.351  -0.430  -0.334  -0.270  -0.364  -0.279
152   K         0.234   0.148   0.072   0.368   0.249   0.142   0.177   0.044  -0.071
153   V         0.234   0.128   0.076   0.336   0.145   0.073   0.177   0.016  -0.064
154   F         1.945   1.968   2.035   2.160   2.196   2.299   2.189   2.222   2.326
155   L        -0.050  -0.005  -0.033  -0.299  -0.216  -0.290  -0.270  -0.199  -0.240
156   D         0.234   0.305   0.124   0.229   0.331   0.069   0.177   0.283   0.008
157   S         1.945   1.968   2.035   1.955   1.990   2.093   2.189   2.222   2.326
158   D         1.945   1.968   2.035   1.859   1.893   1.997   2.189   2.222   2.326
159   A        -0.678  -0.648  -0.638  -0.598  -0.553  -0.529  -0.717  -0.679  -0.647
160   D         1.945   1.968   2.035   1.859   1.893   1.997   2.189   2.222   2.326
161   K        -0.678  -0.712  -0.666  -0.705  -0.770  -0.699  -0.717  -0.746  -0.675
162   R         1.945   1.968   2.035   2.052   2.080   2.191   2.189   2.222   2.326
163   L         1.945   1.968   2.035   1.779   1.810   1.917   2.189   2.222   2.326
164   I         1.056   0.919   0.908   1.071   0.910   0.890   1.071   0.826   0.777
165   S        -0.050   0.023  -0.044  -0.106   0.012  -0.099  -0.270  -0.166  -0.253
166   L        -0.050  -0.001  -0.027  -0.154  -0.094  -0.120  -0.270  -0.200  -0.225
167   I         1.056   0.919   0.908   1.012   0.823   0.791   1.071   0.826   0.777
168   K        -0.506  -0.536  -0.579  -0.344  -0.418  -0.468  -0.493  -0.534  -0.570
169   K        -0.678  -0.636  -0.644  -0.673  -0.620  -0.612  -0.717  -0.668  -0.651
170   K        -0.050  -0.001  -0.027  -0.274  -0.192  -0.227  -0.270  -0.200  -0.225
171   N        -0.678  -0.713  -0.668  -0.613  -0.668  -0.567  -0.717  -0.748  -0.677
172   V        -0.678  -0.712  -0.666  -0.973  -1.047  -0.962  -0.717  -0.746  -0.675
173   G        -1.133  -1.141  -1.094  -1.085  -1.070  -1.010  -0.940  -0.944  -0.871
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   S        -1.133  -1.076  -1.082  -0.997  -0.905  -0.911  -0.940  -0.875  -0.859
177   N        -0.678  -0.641  -0.635  -0.640  -0.573  -0.566  -0.717  -0.672  -0.644
178   E        -0.678  -0.716  -0.648  -0.884  -0.948  -0.836  -0.717  -0.750  -0.656
179   Q        -0.678  -0.713  -0.668  -0.681  -0.731  -0.671  -0.717  -0.748  -0.677
180   L         1.945   1.968   2.035   1.779   1.810   1.917   2.189   2.222   2.326
181   A         0.578   0.594   0.667   0.359   0.380   0.501   0.177   0.200   0.303
182   Q        -1.133  -1.139  -1.094  -0.975  -1.004  -0.903  -0.940  -0.942  -0.870
183   L        -0.506  -0.405  -0.567  -0.338  -0.196  -0.429  -0.493  -0.362  -0.556
184   I         0.690   0.653   0.691   0.322   0.247   0.270   0.401   0.321   0.354
185   T        -1.133  -1.131  -1.123  -1.013  -1.033  -0.995  -0.940  -0.934  -0.898
186   E        -0.678  -0.713  -0.668  -0.718  -0.795  -0.701  -0.717  -0.748  -0.677
187   Y         1.945   1.968   2.035   2.104   2.138   2.243   2.189   2.222   2.326
188   M        -0.050  -0.117  -0.050  -0.153  -0.237  -0.120  -0.270  -0.346  -0.261
189   D        -0.678  -0.722  -0.649  -0.729  -0.773  -0.674  -0.717  -0.755  -0.657
190   H        -0.050  -0.001  -0.027   0.069   0.148   0.113  -0.270  -0.200  -0.225
191   L        -0.050  -0.129  -0.064  -0.305  -0.422  -0.318  -0.270  -0.364  -0.279
192   R         1.945   1.968   2.035   2.052   2.080   2.191   2.189   2.222   2.326
193   P        -0.506  -0.569  -0.602  -0.274  -0.395  -0.451  -0.493  -0.571  -0.598
194   E         1.945   1.968   2.035   1.955   1.980   2.093   2.189   2.222   2.326
195   M         1.945   1.968   2.035   2.219   2.252   2.358   2.189   2.222   2.326
196   Q        -0.506  -0.405  -0.567  -0.466  -0.305  -0.572  -0.493  -0.362  -0.556
197   Q        -0.050   0.013  -0.024  -0.166  -0.061  -0.097  -0.270  -0.182  -0.221
198   Y         0.578   0.598   0.666   0.535   0.570   0.675   0.177   0.208   0.302
199   I         1.945   1.968   2.035   1.851   1.901   1.989   2.189   2.222   2.326
200   E        -0.678  -0.713  -0.668  -0.762  -0.847  -0.781  -0.717  -0.748  -0.677
201   P         1.056   0.919   0.908   1.292   1.081   1.056   1.071   0.826   0.777
202   T         1.056   1.108   0.952   1.280   1.357   1.121   1.071   1.154   0.860
203   R         0.690   0.749   0.741   0.547   0.645   0.617   0.401   0.508   0.454
204   T        -0.050   0.015  -0.043  -0.101  -0.015  -0.082  -0.270  -0.174  -0.251
205   F        -0.050  -0.044  -0.051   0.093   0.094   0.089  -0.270  -0.272  -0.267
206   A         1.945   1.968   2.035   2.064   2.099   2.203   2.189   2.222   2.326
207   D         1.056   1.113   0.944   1.061   1.136   0.921   1.071   1.162   0.845
208   L        -0.050   0.013  -0.042  -0.299  -0.185  -0.299  -0.270  -0.175  -0.249
209   I         1.056   0.919   0.908   1.012   0.823   0.791   1.071   0.826   0.777
210   I        -0.050  -0.050  -0.063  -0.331  -0.352  -0.340  -0.270  -0.281  -0.283
211   P         1.945   1.968   2.035   2.144   2.175   2.283   2.189   2.222   2.326
212   S        -0.678  -0.633  -0.645  -0.694  -0.624  -0.630  -0.717  -0.663  -0.653
213   T        -0.050   0.023  -0.044  -0.015   0.098   0.007  -0.270  -0.166  -0.253
214   N         0.578   0.598   0.666   0.397   0.437   0.536   0.177   0.208   0.302
215   E         0.234   0.310   0.116   0.254   0.363   0.052   0.177   0.290  -0.004
216   N        -1.133  -1.053  -1.089  -0.994  -0.845  -0.937  -0.940  -0.851  -0.865
217   L        -0.678  -0.712  -0.666  -0.804  -0.814  -0.759  -0.717  -0.746  -0.675
218   G         0.690   0.724   0.755   0.652   0.711   0.747   0.401   0.459   0.482
219   R        -0.506  -0.412  -0.527  -0.393  -0.257  -0.430  -0.493  -0.371  -0.507
220   A        -0.506  -0.569  -0.602  -0.334  -0.451  -0.500  -0.493  -0.571  -0.598
221   V        -0.050   0.023  -0.044  -0.416  -0.300  -0.399  -0.270  -0.166  -0.253
222   L         0.234   0.164   0.076   0.146   0.047  -0.125   0.177   0.066  -0.064
223   V         0.234   0.128   0.076   0.309   0.125   0.033   0.177   0.016  -0.064
224   D         1.056   0.919   0.908   1.020   0.816   0.799   1.071   0.826   0.777
225   G         1.945   1.968   2.035   2.064   2.101   2.203   2.189   2.222   2.326
226   I        -0.506  -0.553  -0.566  -0.549  -0.651  -0.643  -0.493  -0.553  -0.555
227   V        -0.050  -0.129  -0.064   0.035  -0.077   0.038  -0.270  -0.364  -0.279
228   K        -0.050  -0.129  -0.064  -0.304  -0.416  -0.324  -0.270  -0.364  -0.279
229   A        -1.589  -1.571  -1.509  -1.544  -1.504  -1.418  -1.164  -1.141  -1.055
230   I        -0.050   0.023  -0.044  -0.368  -0.262  -0.360  -0.270  -0.166  -0.253
231   E        -0.050   0.007  -0.015  -0.119  -0.021  -0.045  -0.270  -0.183  -0.210
232   D        -0.222  -0.206  -0.138  -0.427  -0.381  -0.295  -0.493  -0.469  -0.379
233   T        -1.133  -1.060  -1.082  -1.020  -0.924  -0.934  -0.940  -0.859  -0.859
234   K        -1.589  -1.571  -1.509  -1.400  -1.378  -1.275  -1.164  -1.141  -1.055
235   S        -1.589  -1.571  -1.509  -1.381  -1.315  -1.255  -1.164  -1.141  -1.055
236   Q        -0.683  -0.609  -0.631  -0.566  -0.459  -0.478  -0.708  -0.614  -0.632
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   I        -1.230  -1.214  -1.149  -1.216  -1.200  -1.090  -1.030  -1.008  -0.920
240   E        -1.133  -1.063  -1.086  -1.103  -0.971  -1.041  -0.940  -0.862  -0.863
241   G        -1.133  -1.152  -1.112  -0.980  -1.023  -0.952  -0.940  -0.953  -0.887
242   N        -1.589  -1.571  -1.509  -1.351  -1.298  -1.225  -1.164  -1.141  -1.055
243   N        -1.133  -1.152  -1.112  -1.054  -1.088  -1.024  -0.940  -0.953  -0.887
244   T        -1.589  -1.571  -1.509  -1.279  -1.274  -1.152  -1.164  -1.141  -1.055
245   N        -1.133  -1.153  -1.114  -0.947  -0.990  -0.907  -0.940  -0.955  -0.889
246   N        -1.589  -1.571  -1.509  -1.395  -1.336  -1.269  -1.164  -1.141  -1.055
247   K        -0.050  -0.129  -0.064  -0.188  -0.307  -0.211  -0.270  -0.364  -0.279
248   -        -0.789  -0.769  -0.707  -0.955  -0.923  -0.827  -0.829  -0.801  -0.717
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   I         0.234   0.331   0.105   0.106   0.251  -0.098   0.177   0.322  -0.020
251   R         1.056   1.108   0.952   1.242   1.307   1.105   1.071   1.154   0.860
252   P         0.234   0.148   0.072   0.451   0.299   0.167   0.177   0.044  -0.071
253   R        -0.506  -0.427  -0.547  -0.209  -0.079  -0.279  -0.493  -0.389  -0.532
254   L        -0.506  -0.569  -0.602  -0.651  -0.768  -0.804  -0.493  -0.571  -0.598
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   W        -0.106  -0.082  -0.056   0.132   0.174   0.199  -0.326  -0.290  -0.261
257   D         0.234   0.284   0.103   0.197   0.274  -0.009   0.177   0.252  -0.024
258   F         1.056   0.919   0.908   1.275   1.054   1.015   1.071   0.826   0.777
259   E        -1.589  -1.571  -1.509  -1.567  -1.518  -1.442  -1.164  -1.141  -1.055
260   A        -1.589  -1.571  -1.509  -1.593  -1.570  -1.467  -1.164  -1.141  -1.055
261   E         1.945   1.968   2.035   1.955   1.980   2.093   2.189   2.222   2.326
262   T        -1.133  -1.133  -1.091  -0.925  -0.916  -0.857  -0.940  -0.937  -0.868
263   M        -0.050  -0.129  -0.064   0.071  -0.077   0.020  -0.270  -0.364  -0.279
264   D         1.056   1.108   0.952   1.009   1.081   0.853   1.071   1.154   0.860
265   L        -0.683  -0.678  -0.666  -0.849  -0.842  -0.806  -0.708  -0.696  -0.671
266   E         0.618   0.636   0.686   0.529   0.561   0.621   0.258   0.286   0.342
267   K         0.234   0.148   0.072   0.354   0.232   0.122   0.177   0.044  -0.071
268   D        -1.589  -1.571  -1.509  -1.490  -1.428  -1.364  -1.164  -1.141  -1.055
269   R         0.690   0.724   0.755   0.592   0.644   0.683   0.401   0.459   0.482
270   Y         0.690   0.724   0.755   0.732   0.787   0.829   0.401   0.459   0.482
271   Y         1.056   0.919   0.908   1.264   1.056   1.036   1.071   0.826   0.777
272   D         0.578   0.594   0.667   0.207   0.220   0.341   0.177   0.200   0.303
273   L         1.056   1.102   0.950   0.907   0.974   0.738   1.071   1.145   0.857
274   S        -0.506  -0.562  -0.571  -0.394  -0.472  -0.486  -0.493  -0.563  -0.560
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12084
Output conservation file - output/Q12084
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
