1     M         1.759   1.778   1.961   1.989   2.016   2.290   1.967   1.999   2.307
2     -        -0.092  -0.028  -0.071  -0.176  -0.082  -0.206  -0.304  -0.228  -0.317
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.087  -1.154  -1.012  -1.055  -1.159  -0.985  -0.976  -1.024  -0.841
9     S         0.138   0.030  -0.025   0.117  -0.030  -0.194   0.006  -0.132  -0.255
10    V         0.034   0.124  -0.013  -0.082   0.054  -0.154  -0.172  -0.038  -0.241
11    F         0.546   0.570   0.468   0.412   0.455   0.314   0.337   0.378   0.179
12    V         0.667   0.702   0.514   0.603   0.624   0.367   0.566   0.595   0.268
13    S         0.783   0.812   0.937   0.567   0.612   0.748   0.439   0.482   0.583
14    G         1.759   1.778   1.961   1.793   1.819   2.097   1.967   1.999   2.307
15    A         0.696   0.535   0.186   0.777   0.590   0.131   0.821   0.594   0.066
16    N         0.457   0.463   0.434   0.312   0.311   0.290   0.159   0.152   0.101
17    G         1.759   1.778   1.961   1.793   1.819   2.097   1.967   1.999   2.307
18    F         1.759   1.778   1.961   1.804   1.830   2.108   1.967   1.999   2.307
19    I         0.880   0.966   1.025   0.749   0.890   0.918   0.643   0.802   0.783
20    A         1.399   1.290   1.231   1.341   1.228   1.176   1.559   1.392   1.219
21    Q        -0.580  -0.565  -0.457  -0.674  -0.690  -0.547  -0.757  -0.756  -0.590
22    H         1.044   1.022   0.674   1.385   1.368   0.958   1.177   1.147   0.561
23    I         0.060   0.088   0.275  -0.149  -0.129   0.133  -0.375  -0.338  -0.128
24    V        -0.093  -0.176  -0.068  -0.313  -0.434  -0.320  -0.350  -0.436  -0.329
25    D        -0.653  -0.680  -0.702  -0.592  -0.675  -0.734  -0.655  -0.704  -0.683
26    L         0.618   0.616   0.480   0.811   0.810   0.533   0.541   0.532   0.226
27    L         1.759   1.778   1.961   1.641   1.671   1.949   1.967   1.999   2.307
28    L         1.399   1.391   1.238   1.364   1.365   1.205   1.559   1.550   1.233
29    K        -0.892  -0.933  -0.921  -1.008  -1.041  -0.998  -0.834  -0.859  -0.771
30    E        -1.070  -1.025  -1.136  -0.988  -0.958  -1.083  -0.859  -0.831  -0.849
31    D         0.464   0.539   0.410   0.502   0.608   0.356   0.286   0.399   0.104
32    Y         0.645   0.665   0.877   0.571   0.595   0.898   0.134   0.156   0.441
33    K        -1.080  -1.088  -0.989  -1.080  -1.081  -0.929  -0.961  -0.969  -0.826
34    V         1.759   1.778   1.961   1.675   1.694   1.982   1.967   1.999   2.307
35    I         0.333   0.205   0.064   0.431   0.271   0.050   0.261   0.089  -0.130
36    G         1.399   1.330   1.231   1.513   1.444   1.333   1.559   1.456   1.219
37    S         1.008   1.066   1.062   0.952   1.038   0.990   0.897   0.996   0.864
38    A         0.546   0.607   0.471   0.420   0.508   0.291   0.337   0.440   0.173
39    R         1.759   1.778   1.961   1.925   1.948   2.227   1.967   1.999   2.307
40    S         0.152   0.194  -0.213   0.412   0.471  -0.041   0.210   0.273  -0.270
41    Q        -1.204  -1.235  -1.047  -1.171  -1.196  -0.981  -1.063  -1.079  -0.868
42    E        -0.703  -0.658  -0.733  -0.616  -0.565  -0.720  -0.681  -0.639  -0.707
43    K         1.759   1.778   1.961   1.634   1.661   1.942   1.967   1.999   2.307
44    A         0.713   0.748   0.900   0.353   0.407   0.607   0.286   0.344   0.496
45    E        -0.726  -0.736  -0.726  -0.755  -0.779  -0.779  -0.757  -0.775  -0.709
46    N        -1.123  -1.145  -0.996  -0.956  -1.003  -0.830  -1.012  -1.020  -0.830
47    L         1.008   1.003   1.031   0.871   0.861   0.861   0.897   0.875   0.798
48    T        -1.385  -1.464  -1.386  -1.347  -1.417  -1.286  -1.063  -1.105  -0.959
49    E        -0.726  -0.719  -0.697  -0.790  -0.760  -0.733  -0.757  -0.743  -0.677
50    A        -0.043  -0.058  -0.289  -0.011  -0.053  -0.377  -0.044  -0.087  -0.375
51    F        -0.274  -0.369  -0.359  -0.229  -0.320  -0.343  -0.401  -0.484  -0.475
52    G        -1.030  -0.927  -0.946  -0.991  -0.816  -0.852  -0.935  -0.830  -0.785
53    N        -1.206  -1.221  -1.032  -1.305  -1.317  -1.030  -1.080  -1.084  -0.859
54    -        -0.479  -0.502  -0.459  -0.713  -0.763  -0.667  -0.648  -0.672  -0.583
55    -        -0.606  -0.654  -0.501  -0.691  -0.777  -0.567  -0.769  -0.810  -0.626
56    -        -1.313  -1.293  -1.055  -1.556  -1.536  -1.234  -1.150  -1.130  -0.873
57    N        -0.405  -0.405  -0.606  -0.280  -0.288  -0.540  -0.426  -0.426  -0.587
58    P        -0.623  -0.718  -1.053  -0.160  -0.286  -0.811  -0.350  -0.457  -0.764
59    K        -0.179  -0.154  -0.335  -0.152  -0.113  -0.370  -0.248  -0.211  -0.439
60    F        -0.037  -0.070   0.005  -0.174  -0.194  -0.084  -0.299  -0.316  -0.237
61    S        -1.573  -1.538  -1.394  -1.507  -1.468  -1.325  -1.190  -1.160  -0.964
62    M        -0.498  -0.513  -0.434  -0.564  -0.559  -0.402  -0.706  -0.703  -0.566
63    E         0.828   0.688   0.520   0.890   0.684   0.408   0.846   0.602   0.282
64    V         0.103   0.128   0.289  -0.206  -0.177   0.035  -0.324  -0.303  -0.112
65    V         0.783   0.840   0.954   0.476   0.568   0.686   0.439   0.542   0.622
66    P        -0.817  -0.796  -0.715  -0.971  -0.943  -0.814  -0.859  -0.842  -0.702
67    D         1.759   1.778   1.961   1.745   1.769   2.051   1.967   1.999   2.307
68    I         0.713   0.722   0.890   0.429   0.423   0.636   0.286   0.284   0.473
69    S        -0.679  -0.646  -0.485  -0.762  -0.735  -0.496  -0.859  -0.825  -0.617
70    K        -1.424  -1.413  -1.241  -1.523  -1.534  -1.276  -1.165  -1.148  -0.930
71    L        -1.030  -1.085  -0.976  -1.071  -1.149  -1.035  -0.935  -0.972  -0.816
72    D        -1.204  -1.089  -1.148  -1.125  -0.998  -1.060  -1.012  -0.934  -0.868
73    A         0.645   0.679   0.884   0.187   0.239   0.535   0.134   0.189   0.458
74    F         1.176   1.190   1.134   1.252   1.271   1.162   1.203   1.223   1.020
75    D         0.034   0.161   0.002  -0.043   0.131  -0.097  -0.172  -0.010  -0.226
76    H        -1.523  -1.554  -1.545  -1.282  -1.345  -1.331  -1.063  -1.090  -0.997
77    V         0.144   0.220   0.299  -0.178  -0.059  -0.002  -0.248  -0.134  -0.088
78    F         0.667   0.522   0.456   0.725   0.506   0.340   0.566   0.329   0.154
79    Q        -0.498  -0.498  -0.418  -0.652  -0.665  -0.533  -0.706  -0.706  -0.557
80    K         1.013   0.894   0.628   1.043   0.914   0.563   1.133   0.957   0.483
81    H         1.759   1.778   1.961   1.928   1.955   2.230   1.967   1.999   2.307
82    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    K        -0.446  -0.437  -0.417  -0.530  -0.489  -0.490  -0.620  -0.593  -0.543
84    D         0.062   0.045   0.018  -0.115  -0.123  -0.113  -0.248  -0.259  -0.236
85    I         0.220   0.116   0.030   0.191   0.053  -0.124   0.057  -0.071  -0.199
86    K        -0.785  -0.841  -0.921  -0.748  -0.842  -0.973  -0.681  -0.744  -0.761
87    I        -0.223  -0.281  -0.345  -0.226  -0.309  -0.364  -0.426  -0.469  -0.470
88    V         0.140   0.129   0.031   0.010  -0.006  -0.102  -0.095  -0.105  -0.201
89    L         0.696   0.589   0.194   0.844   0.739   0.295   0.821   0.669   0.078
90    H         1.759   1.778   1.961   1.929   1.956   2.231   1.967   1.999   2.307
91    T         1.044   0.927   0.658   1.162   1.039   0.682   1.177   1.005   0.533
92    A         1.759   1.778   1.961   1.617   1.643   1.926   1.967   1.999   2.307
93    S         1.759   1.778   1.961   1.750   1.773   2.055   1.967   1.999   2.307
94    P         1.759   1.778   1.961   1.827   1.854   2.131   1.967   1.999   2.307
95    F         1.176   1.241   1.071   1.252   1.338   1.046   1.203   1.310   0.885
96    C        -0.679  -0.632  -0.478  -0.676  -0.610  -0.369  -0.859  -0.813  -0.610
97    F         0.333   0.272   0.074   0.542   0.456   0.215   0.261   0.172  -0.131
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    D        -0.405  -0.373  -0.410  -0.342  -0.303  -0.468  -0.477  -0.443  -0.520
100   I        -1.228  -1.212  -1.000  -1.419  -1.381  -1.108  -1.088  -1.066  -0.833
101   T         0.351   0.415   0.365   0.205   0.313   0.146   0.083   0.184   0.020
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   D         0.486   0.561   0.193   0.654   0.745   0.274   0.516   0.619   0.075
106   S        -0.604  -0.569  -0.676  -0.466  -0.455  -0.571  -0.630  -0.616  -0.658
107   E         0.138   0.049  -0.033   0.117  -0.035  -0.210   0.006  -0.132  -0.267
108   R        -0.311  -0.450  -0.609  -0.220  -0.379  -0.608  -0.274  -0.414  -0.579
109   D         0.034  -0.038   0.005   0.003  -0.083  -0.053  -0.172  -0.258  -0.238
110   L         0.219   0.301   0.404   0.080   0.187   0.353  -0.172  -0.047   0.061
111   L         1.044   0.952   0.660   1.080   0.985   0.611   1.177   1.045   0.538
112   I        -0.942  -0.945  -0.798  -1.030  -1.058  -0.876  -0.961  -0.966  -0.770
113   P         1.759   1.778   1.961   1.827   1.854   2.131   1.967   1.999   2.307
114   A         1.759   1.778   1.961   1.617   1.643   1.926   1.967   1.999   2.307
115   V         0.138   0.198   0.068   0.098   0.181  -0.042   0.006   0.095  -0.131
116   N        -1.017  -0.966  -0.959  -0.927  -0.889  -0.826  -0.935  -0.898  -0.803
117   G         1.759   1.778   1.961   1.793   1.819   2.097   1.967   1.999   2.307
118   V         1.399   1.420   1.239   1.443   1.474   1.271   1.559   1.592   1.236
119   K        -0.545  -0.542  -0.462  -0.759  -0.761  -0.646  -0.706  -0.708  -0.592
120   G        -0.761  -0.707  -0.529  -0.986  -0.886  -0.686  -0.910  -0.852  -0.652
121   I         0.713   0.698   0.886   0.392   0.342   0.611   0.286   0.232   0.463
122   L         1.759   1.778   1.961   1.641   1.671   1.949   1.967   1.999   2.307
123   H        -0.226  -0.209  -0.111  -0.466  -0.441  -0.244  -0.554  -0.540  -0.390
124   S        -0.636  -0.523  -0.651  -0.718  -0.602  -0.672  -0.706  -0.603  -0.642
125   I        -0.233  -0.223  -0.128  -0.517  -0.506  -0.398  -0.528  -0.517  -0.400
126   K        -0.168  -0.244  -0.342  -0.206  -0.294  -0.383  -0.324  -0.413  -0.464
127   K        -1.392  -1.433  -1.381  -1.263  -1.299  -1.266  -1.037  -1.064  -0.954
128   Y        -0.386  -0.464  -0.409  -0.220  -0.307  -0.254  -0.562  -0.624  -0.532
129   A         0.360   0.284   0.405   0.042  -0.036   0.154  -0.044  -0.121   0.040
130   A        -0.676  -0.685  -0.703  -0.706  -0.729  -0.724  -0.732  -0.743  -0.686
131   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   S        -0.175  -0.227  -0.148  -0.190  -0.277  -0.222  -0.401  -0.474  -0.416
133   V         1.008   0.937   0.973   0.905   0.778   0.781   0.897   0.743   0.665
134   E        -0.405  -0.464  -0.621  -0.325  -0.392  -0.565  -0.426  -0.489  -0.602
135   R         0.219   0.244   0.380   0.035   0.064   0.285  -0.172  -0.160   0.011
136   V         0.667   0.692   0.498   0.635   0.641   0.388   0.566   0.577   0.232
137   V         1.399   1.445   1.247   1.397   1.444   1.252   1.559   1.629   1.252
138   L         0.219   0.253   0.312  -0.054   0.003   0.041  -0.172  -0.118  -0.074
139   T         1.759   1.778   1.961   1.726   1.756   2.032   1.967   1.999   2.307
140   S         1.759   1.778   1.961   1.750   1.773   2.055   1.967   1.999   2.307
141   S         1.759   1.778   1.961   1.750   1.773   2.055   1.967   1.999   2.307
142   Y        -0.808  -0.733  -0.721  -0.720  -0.604  -0.655  -0.808  -0.726  -0.697
143   A         1.399   1.416   1.235   1.333   1.357   1.157   1.559   1.587   1.227
144   A         0.880   0.911   0.936   0.637   0.681   0.651   0.643   0.692   0.581
145   V        -0.489  -0.464  -0.446  -0.417  -0.405  -0.363  -0.655  -0.632  -0.573
146   F        -1.129  -1.142  -1.131  -0.928  -0.933  -0.900  -0.935  -0.926  -0.848
147   D        -0.817  -0.763  -0.722  -0.820  -0.764  -0.653  -0.859  -0.814  -0.707
148   M        -1.956  -1.926  -1.748  -1.748  -1.721  -1.437  -1.310  -1.285  -1.066
149   A        -1.485  -1.502  -1.238  -1.483  -1.482  -1.128  -1.195  -1.192  -0.927
150   K        -1.059  -1.033  -0.956  -1.067  -1.037  -0.888  -0.965  -0.939  -0.800
151   E        -1.904  -1.886  -1.738  -1.549  -1.550  -1.409  -1.281  -1.265  -1.062
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   N        -1.704  -1.718  -1.560  -1.408  -1.431  -1.213  -1.215  -1.217  -1.011
156   D         0.828   0.718   0.550   0.948   0.829   0.586   0.846   0.689   0.336
157   K        -0.179  -0.229  -0.363  -0.033  -0.084  -0.363  -0.248  -0.296  -0.475
158   S        -0.364  -0.324  -0.363  -0.445  -0.392  -0.429  -0.554  -0.513  -0.496
159   L        -1.704  -1.667  -1.442  -1.617  -1.577  -1.331  -1.266  -1.238  -0.993
160   T        -0.439  -0.421  -0.393  -0.622  -0.603  -0.544  -0.630  -0.611  -0.523
161   F        -1.523  -1.468  -1.264  -1.473  -1.389  -1.112  -1.215  -1.175  -0.943
162   N         0.002  -0.020  -0.035  -0.046  -0.055  -0.133  -0.197  -0.209  -0.277
163   E         1.759   1.778   1.961   1.725   1.753   2.031   1.967   1.999   2.307
164   E        -1.120  -1.065  -1.134  -1.055  -1.001  -1.117  -0.885  -0.841  -0.843
165   S        -0.093  -0.111  -0.065  -0.208  -0.244  -0.196  -0.350  -0.379  -0.327
166   W         1.759   1.778   1.961   1.990   2.017   2.291   1.967   1.999   2.307
167   N         1.759   1.778   1.961   1.784   1.810   2.089   1.967   1.999   2.307
168   P         0.152   0.177  -0.229   0.495   0.535   0.005   0.210   0.251  -0.289
169   A        -0.580  -0.495  -0.402  -0.685  -0.587  -0.448  -0.757  -0.670  -0.529
170   T         0.667   0.692   0.510   0.679   0.706   0.441   0.566   0.590   0.255
171   W         0.284   0.190   0.040   0.701   0.578   0.344   0.236   0.099  -0.160
172   E         0.333   0.317   0.060   0.413   0.383   0.030   0.261   0.223  -0.150
173   S        -0.545  -0.528  -0.464  -0.533  -0.540  -0.478  -0.706  -0.705  -0.596
174   C         0.333   0.307   0.087   0.369   0.351   0.082   0.261   0.243  -0.093
175   Q        -0.653  -0.735  -0.713  -0.614  -0.725  -0.695  -0.655  -0.734  -0.689
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   S        -1.392  -1.452  -1.392  -1.152  -1.248  -1.246  -1.037  -1.083  -0.960
179   D         0.713   0.749   0.901   0.481   0.539   0.719   0.286   0.346   0.499
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   P        -0.487  -0.470  -0.647  -0.322  -0.321  -0.633  -0.477  -0.478  -0.632
182   V        -0.899  -0.896  -0.748  -1.011  -1.040  -0.817  -0.910  -0.915  -0.726
183   N        -1.023  -1.018  -0.816  -1.260  -1.272  -0.993  -1.012  -1.008  -0.783
184   A        -0.440  -0.321  -0.385  -0.585  -0.407  -0.507  -0.579  -0.430  -0.492
185   Y         1.759   1.778   1.961   1.939   1.963   2.241   1.967   1.999   2.307
186   C        -1.336  -1.308  -1.211  -1.070  -1.029  -0.868  -1.088  -1.073  -0.910
187   G         0.668   0.671   0.877   0.315   0.291   0.580   0.185   0.169   0.442
188   S         1.399   1.391   1.238   1.463   1.457   1.280   1.559   1.550   1.233
189   K         1.759   1.778   1.961   1.634   1.661   1.942   1.967   1.999   2.307
190   K        -0.274  -0.188  -0.346  -0.420  -0.329  -0.547  -0.401  -0.332  -0.463
191   F         0.034  -0.002  -0.042   0.122   0.047   0.011  -0.172  -0.226  -0.285
192   A         1.759   1.778   1.961   1.617   1.643   1.926   1.967   1.999   2.307
193   E         1.759   1.778   1.961   1.725   1.753   2.031   1.967   1.999   2.307
194   K         0.486   0.421   0.099   0.563   0.471   0.065   0.516   0.405  -0.078
195   A         0.618   0.665   0.553   0.525   0.591   0.395   0.541   0.610   0.352
196   A         0.667   0.777   0.561   0.579   0.729   0.447   0.566   0.742   0.356
197   W         0.152   0.168  -0.220   0.613   0.649   0.088   0.210   0.234  -0.279
198   E         0.360   0.371   0.421   0.100   0.118   0.222  -0.044  -0.027   0.065
199   F         1.176   1.106   1.050   1.291   1.203   1.107   1.203   1.072   0.839
200   L        -0.703  -0.547  -0.846  -0.599  -0.404  -0.709  -0.630  -0.465  -0.700
201   E        -0.498  -0.479  -0.414  -0.716  -0.670  -0.535  -0.706  -0.672  -0.549
202   E        -1.392  -1.311  -1.217  -1.371  -1.278  -1.128  -1.139  -1.084  -0.916
203   N        -0.210  -0.334  -0.349  -0.255  -0.376  -0.386  -0.401  -0.499  -0.471
204   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   S        -0.037   0.007  -0.050  -0.246  -0.198  -0.268  -0.299  -0.262  -0.308
207   V         0.144   0.165   0.297  -0.055  -0.038   0.107  -0.248  -0.229  -0.095
208   K        -1.260  -1.201  -1.176  -1.121  -1.061  -0.987  -1.012  -0.968  -0.879
209   F         1.176   1.106   1.050   1.291   1.203   1.107   1.203   1.072   0.839
210   E        -1.254  -1.238  -1.178  -1.221  -1.222  -1.110  -1.037  -1.031  -0.885
211   L         0.880   0.892   0.974   0.665   0.680   0.754   0.643   0.652   0.669
212   T         0.284   0.167   0.006   0.381   0.246  -0.053   0.236   0.079  -0.209
213   A         0.034   0.136   0.011   0.043   0.179  -0.002  -0.172  -0.033  -0.204
214   V         0.668   0.680   0.881   0.302   0.306   0.601   0.185   0.191   0.450
215   N         1.399   1.433   1.242   1.506   1.546   1.346   1.559   1.611   1.241
216   P         1.759   1.778   1.961   1.827   1.854   2.131   1.967   1.999   2.307
217   V        -0.679  -0.633  -0.499  -0.964  -0.897  -0.700  -0.859  -0.820  -0.631
218   Y        -0.043  -0.099  -0.314   0.302   0.242  -0.130  -0.044  -0.110  -0.403
219   V         0.880   0.966   1.025   0.698   0.826   0.880   0.643   0.802   0.783
220   F         0.667   0.624   0.534   0.745   0.729   0.563   0.566   0.530   0.305
221   G         1.759   1.778   1.961   1.793   1.819   2.097   1.967   1.999   2.307
222   P         1.759   1.778   1.961   1.827   1.854   2.131   1.967   1.999   2.307
223   Q        -0.620  -0.721  -0.700  -0.426  -0.521  -0.506  -0.681  -0.751  -0.681
224   M        -1.080  -1.050  -0.975  -1.100  -1.073  -0.985  -0.961  -0.935  -0.812
225   F        -0.892  -0.827  -0.756  -0.923  -0.829  -0.689  -0.935  -0.889  -0.739
226   D        -1.615  -1.573  -1.444  -1.597  -1.512  -1.386  -1.201  -1.169  -0.992
227   K        -1.036  -1.056  -0.824  -1.156  -1.157  -0.885  -1.031  -1.041  -0.789
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   D        -1.030  -1.126  -1.003  -1.102  -1.243  -1.102  -0.935  -1.001  -0.836
230   V        -0.834  -0.933  -0.948  -0.692  -0.825  -0.928  -0.706  -0.792  -0.781
231   K        -0.849  -0.808  -0.748  -0.917  -0.872  -0.756  -0.885  -0.859  -0.731
232   K        -0.857  -0.889  -0.921  -0.871  -0.910  -0.960  -0.783  -0.809  -0.773
233   H        -0.767  -0.703  -0.884  -0.770  -0.681  -0.845  -0.732  -0.672  -0.739
234   L         1.008   1.015   1.001   0.871   0.880   0.805   0.897   0.899   0.730
235   N         1.759   1.778   1.961   1.784   1.810   2.089   1.967   1.999   2.307
236   T         1.044   1.125   0.696   1.155   1.249   0.719   1.177   1.290   0.599
237   S         1.759   1.778   1.961   1.750   1.773   2.055   1.967   1.999   2.307
238   C         0.034   0.096   0.026   0.029   0.121   0.025  -0.172  -0.089  -0.200
239   E         0.034   0.016  -0.038   0.004  -0.014  -0.087  -0.172  -0.197  -0.280
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   L        -0.498  -0.499  -0.405  -0.713  -0.688  -0.520  -0.706  -0.693  -0.542
242   V         0.088   0.051   0.022  -0.066  -0.090  -0.110  -0.197  -0.221  -0.225
243   N        -0.668  -0.689  -0.894  -0.381  -0.395  -0.730  -0.528  -0.548  -0.732
244   S        -1.467  -1.464  -1.367  -1.284  -1.305  -1.178  -1.114  -1.111  -0.948
245   L        -0.154  -0.072  -0.049  -0.515  -0.366  -0.349  -0.452  -0.334  -0.303
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   M        -0.043  -0.053  -0.305   0.038   0.007  -0.322  -0.044  -0.081  -0.395
248   H        -1.211  -1.155  -1.031  -1.217  -1.155  -0.952  -1.088  -1.049  -0.859
249   L        -0.580  -0.597  -0.477  -0.813  -0.833  -0.665  -0.757  -0.773  -0.605
250   S         0.284   0.228   0.067   0.287   0.210  -0.045   0.236   0.148  -0.123
251   P        -0.168  -0.179  -0.313  -0.147  -0.151  -0.306  -0.324  -0.338  -0.433
252   E        -0.725  -0.791  -0.745  -0.674  -0.767  -0.772  -0.735  -0.790  -0.720
253   D        -0.259  -0.234  -0.105  -0.321  -0.307  -0.147  -0.528  -0.505  -0.372
254   K        -1.704  -1.747  -1.574  -1.612  -1.693  -1.515  -1.215  -1.230  -1.019
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   I        -1.080  -1.121  -0.984  -1.017  -1.082  -0.949  -0.961  -0.988  -0.820
257   P        -0.668  -0.555  -0.865  -0.364  -0.212  -0.725  -0.528  -0.410  -0.704
258   E        -1.625  -1.657  -1.424  -1.519  -1.561  -1.273  -1.223  -1.230  -0.982
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   L        -1.704  -1.665  -1.558  -1.490  -1.442  -1.350  -1.215  -1.179  -1.010
262   F        -0.174  -0.244  -0.567  -0.027  -0.117  -0.560  -0.070  -0.166  -0.527
263   G        -0.491  -0.603  -0.854  -0.061  -0.202  -0.516  -0.324  -0.453  -0.688
264   G        -1.517  -1.483  -1.408  -1.196  -1.166  -1.078  -1.139  -1.116  -0.973
265   Y        -0.836  -0.783  -0.713  -0.621  -0.554  -0.390  -0.885  -0.846  -0.701
266   I         0.271   0.306   0.401   0.092   0.119   0.267  -0.070  -0.036   0.054
267   D         1.759   1.778   1.961   1.745   1.769   2.051   1.967   1.999   2.307
268   V         1.759   1.778   1.961   1.675   1.694   1.982   1.967   1.999   2.307
269   R         1.759   1.778   1.961   1.925   1.948   2.227   1.967   1.999   2.307
270   D         1.399   1.402   1.239   1.469   1.477   1.312   1.559   1.566   1.236
271   V         0.546   0.641   0.516   0.515   0.640   0.510   0.337   0.498   0.268
272   A         1.759   1.778   1.961   1.617   1.643   1.926   1.967   1.999   2.307
273   K         0.140   0.090   0.023   0.039  -0.029  -0.081  -0.095  -0.160  -0.218
274   A         0.828   0.879   0.632   0.788   0.858   0.540   0.846   0.926   0.489
275   H         1.759   1.778   1.961   1.929   1.956   2.231   1.967   1.999   2.307
276   L        -0.143  -0.113  -0.095  -0.324  -0.295  -0.323  -0.375  -0.348  -0.352
277   V        -0.998  -1.073  -0.975  -1.023  -1.084  -0.929  -0.910  -0.954  -0.816
278   A         1.176   1.230   1.199   1.090   1.159   1.137   1.203   1.291   1.156
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   F         0.144   0.185   0.307  -0.152  -0.090   0.058  -0.248  -0.194  -0.077
281   Q        -1.179  -1.074  -0.986  -1.164  -1.034  -0.911  -1.063  -0.980  -0.824
282   K        -0.092  -0.207  -0.121  -0.299  -0.495  -0.404  -0.304  -0.476  -0.388
283   R        -1.286  -1.317  -1.211  -1.191  -1.234  -1.085  -1.063  -1.073  -0.908
284   E        -0.037  -0.022  -0.049  -0.229  -0.239  -0.264  -0.299  -0.306  -0.309
285   T        -0.259  -0.265  -0.148  -0.529  -0.540  -0.429  -0.528  -0.531  -0.416
286   I        -0.676  -0.785  -0.723  -0.682  -0.809  -0.744  -0.732  -0.814  -0.705
287   G        -0.334  -0.257  -0.339  -0.294  -0.220  -0.277  -0.503  -0.437  -0.465
288   Q        -0.439  -0.465  -0.406  -0.430  -0.469  -0.378  -0.630  -0.650  -0.541
289   R         1.759   1.778   1.961   1.925   1.948   2.227   1.967   1.999   2.307
290   L         1.044   0.927   0.658   1.102   0.987   0.678   1.177   1.005   0.533
291   I        -0.463  -0.432  -0.398  -0.506  -0.461  -0.352  -0.655  -0.610  -0.531
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   V         0.284   0.175   0.051   0.314   0.165  -0.054   0.236   0.082  -0.146
304   S        -1.336  -1.289  -1.197  -1.025  -1.003  -0.913  -1.088  -1.060  -0.898
305   E        -1.211  -1.181  -1.035  -1.402  -1.382  -1.186  -1.088  -1.067  -0.862
306   A         0.002   0.108  -0.028  -0.028   0.146  -0.131  -0.197  -0.040  -0.264
307   R        -0.668  -0.767  -0.909  -0.524  -0.650  -0.891  -0.528  -0.628  -0.746
308   F         1.044   1.134   0.695   1.255   1.351   0.857   1.177   1.302   0.596
309   T        -0.629  -0.634  -0.476  -0.600  -0.634  -0.460  -0.783  -0.789  -0.603
310   M        -0.988  -0.965  -0.953  -0.890  -0.865  -0.883  -0.859  -0.841  -0.789
311   Q         0.486   0.341   0.144   0.805   0.649   0.341   0.516   0.330   0.003
312   D        -0.668  -0.687  -0.872  -0.408  -0.414  -0.684  -0.528  -0.535  -0.705
313   V        -0.210  -0.180  -0.320  -0.293  -0.243  -0.355  -0.401  -0.363  -0.446
314   L        -0.179  -0.295  -0.345  -0.203  -0.317  -0.450  -0.248  -0.359  -0.446
315   D        -0.043  -0.163  -0.305   0.151   0.001  -0.253  -0.044  -0.179  -0.392
316   I         0.152   0.047  -0.272   0.379   0.227  -0.254   0.210   0.060  -0.355
317   L        -0.580  -0.546  -0.455  -0.820  -0.800  -0.626  -0.757  -0.732  -0.584
318   N         1.176   1.045   1.046   1.270   1.096   1.077   1.203   0.956   0.830
319   E        -0.223  -0.182  -0.319  -0.363  -0.314  -0.377  -0.426  -0.381  -0.446
320   D        -0.697  -0.708  -0.487  -0.906  -0.914  -0.609  -0.863  -0.865  -0.617
321   F         0.002   0.148   0.012  -0.013   0.206  -0.039  -0.197   0.004  -0.202
322   P         1.399   1.402   1.239   1.549   1.559   1.384   1.559   1.566   1.236
323   V         0.007  -0.049  -0.288   0.140   0.063  -0.259  -0.019  -0.096  -0.381
324   L        -0.043  -0.176  -0.311   0.041  -0.114  -0.338  -0.044  -0.197  -0.397
325   K        -0.311  -0.398  -0.597  -0.157  -0.268  -0.499  -0.274  -0.376  -0.570
326   G         1.176   1.045   1.046   1.254   1.068   1.022   1.203   0.956   0.830
327   N         0.486   0.407   0.115   0.538   0.450   0.018   0.516   0.415  -0.053
328   I         1.399   1.330   1.231   1.480   1.407   1.288   1.559   1.456   1.219
329   P         0.219   0.257   0.380  -0.073  -0.027   0.158  -0.172  -0.134   0.014
330   V        -1.066  -1.021  -0.786  -1.298  -1.237  -0.930  -1.051  -1.012  -0.760
331   G         1.013   1.018   0.645   1.206   1.217   0.757   1.133   1.140   0.512
332   K        -1.179  -1.102  -0.980  -1.242  -1.126  -0.960  -1.063  -0.996  -0.822
333   P         0.828   0.797   0.624   1.005   0.977   0.720   0.846   0.811   0.474
334   G        -0.668  -0.729  -0.872  -0.448  -0.525  -0.832  -0.528  -0.582  -0.706
335   S        -1.211  -1.209  -1.017  -1.279  -1.276  -1.011  -1.088  -1.077  -0.849
336   G        -0.948  -1.028  -0.953  -0.780  -0.869  -0.785  -0.885  -0.928  -0.794
337   A        -1.342  -1.394  -1.362  -1.236  -1.316  -1.336  -1.012  -1.050  -0.943
338   T        -1.523  -1.561  -1.410  -1.542  -1.587  -1.343  -1.165  -1.177  -0.974
339   H        -1.161  -1.162  -1.163  -1.069  -1.111  -1.065  -0.961  -0.973  -0.876
340   N        -1.211  -1.250  -1.210  -1.186  -1.248  -1.216  -0.986  -1.025  -0.908
341   T        -1.254  -1.224  -1.150  -1.321  -1.273  -1.164  -1.037  -1.011  -0.867
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.342  -1.345  -1.223  -1.292  -1.313  -1.129  -1.081  -1.086  -0.915
344   L        -1.032  -1.090  -1.305  -0.696  -0.774  -1.127  -0.677  -0.743  -0.888
345   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   A        -0.817  -0.689  -0.706  -0.879  -0.706  -0.702  -0.859  -0.740  -0.692
347   T        -1.260  -1.194  -1.026  -1.177  -1.138  -0.911  -1.114  -1.066  -0.854
348   L        -1.260  -1.220  -1.044  -1.122  -1.102  -0.848  -1.114  -1.083  -0.868
349   D         0.486   0.522   0.186   0.683   0.729   0.311   0.516   0.570   0.065
350   N         0.355   0.478  -0.145   0.686   0.818   0.070   0.490   0.643  -0.178
351   K        -0.364  -0.343  -0.181  -0.650  -0.630  -0.438  -0.655  -0.636  -0.459
352   K        -1.655  -1.627  -1.556  -1.612  -1.591  -1.453  -1.190  -1.169  -1.009
353   S         0.880   0.852   0.922   0.743   0.687   0.717   0.643   0.568   0.548
354   K        -0.620  -0.588  -0.634  -0.622  -0.578  -0.611  -0.681  -0.650  -0.623
355   K        -0.356  -0.471  -0.413  -0.393  -0.548  -0.503  -0.452  -0.583  -0.532
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   L         0.650   0.685   0.199   0.742   0.786   0.152   0.760   0.805   0.085
358   L         0.828   0.890   0.641   0.828   0.911   0.605   0.846   0.940   0.504
359   G        -0.577  -0.531  -0.454  -0.686  -0.623  -0.545  -0.732  -0.683  -0.578
360   F        -0.259  -0.200  -0.127  -0.369  -0.288  -0.207  -0.528  -0.460  -0.390
361   K        -0.623  -0.596  -0.429  -0.869  -0.833  -0.582  -0.808  -0.781  -0.568
362   F        -0.078  -0.089  -0.073  -0.014  -0.025   0.020  -0.375  -0.386  -0.336
363   R        -0.487  -0.564  -0.653  -0.220  -0.301  -0.415  -0.477  -0.550  -0.627
364   N        -0.991  -0.941  -0.761  -1.041  -0.983  -0.757  -0.986  -0.943  -0.736
365   L         0.486   0.348   0.106   0.550   0.396   0.022   0.516   0.340  -0.067
366   K        -0.487  -0.326  -0.611  -0.377  -0.154  -0.524  -0.477  -0.290  -0.580
367   E        -0.817  -0.791  -0.709  -0.880  -0.851  -0.698  -0.859  -0.851  -0.699
368   T        -0.751  -0.836  -0.891  -0.613  -0.684  -0.717  -0.706  -0.774  -0.746
369   I         0.088   0.055   0.030  -0.079  -0.108  -0.086  -0.197  -0.231  -0.220
370   D        -1.310  -1.233  -1.199  -1.200  -1.116  -1.045  -1.088  -1.024  -0.901
371   D         1.759   1.778   1.961   1.745   1.769   2.051   1.967   1.999   2.307
372   T         0.194   0.237   0.374  -0.059  -0.007   0.183  -0.223  -0.176   0.002
373   A        -0.154  -0.104  -0.079  -0.487  -0.448  -0.374  -0.452  -0.417  -0.350
374   S        -0.522  -0.436  -0.466  -0.691  -0.563  -0.690  -0.630  -0.529  -0.580
375   Q         0.696   0.535   0.186   1.053   0.868   0.376   0.821   0.594   0.066
376   I        -0.233  -0.287  -0.140  -0.228  -0.326  -0.129  -0.528  -0.586  -0.413
377   L        -0.491  -0.597  -0.851  -0.261  -0.395  -0.749  -0.324  -0.447  -0.686
378   K        -0.653  -0.588  -0.673  -0.649  -0.543  -0.743  -0.655  -0.577  -0.648
379   F        -1.467  -1.470  -1.386  -1.239  -1.224  -1.099  -1.114  -1.105  -0.958
380   E        -1.153  -1.226  -1.175  -0.996  -1.109  -1.031  -0.936  -0.994  -0.882
381   G        -1.313  -1.321  -1.208  -1.268  -1.276  -1.109  -1.048  -1.052  -0.898
382   R        -0.682  -0.582  -0.482  -0.790  -0.640  -0.534  -0.830  -0.723  -0.604
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   I        -1.441  -1.405  -1.239  -1.543  -1.508  -1.287  -1.165  -1.128  -0.927
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12068
Output conservation file - output/Q12068
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
