1     M         1.911   1.937   2.053   2.200   2.240   2.425   2.146   2.186   2.389
2     P        -0.950  -0.884  -0.874  -0.823  -0.719  -0.707  -0.887  -0.819  -0.772
3     T         0.147   0.132   0.124   0.075   0.030  -0.000  -0.089  -0.126  -0.137
4     M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     K        -0.970  -0.965  -0.898  -0.990  -0.976  -0.890  -0.895  -0.887  -0.792
7     K         0.044   0.076   0.097  -0.112  -0.078  -0.042  -0.244  -0.212  -0.176
8     D        -0.383  -0.348  -0.405  -0.318  -0.266  -0.363  -0.461  -0.415  -0.487
9     D        -0.970  -0.965  -0.898  -1.277  -1.285  -1.155  -0.895  -0.887  -0.792
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    K        -0.970  -0.987  -0.909  -0.933  -0.953  -0.825  -0.895  -0.908  -0.803
22    P        -0.383  -0.412  -0.422  -0.284  -0.340  -0.367  -0.461  -0.502  -0.508
23    H        -1.397  -1.370  -1.270  -1.143  -1.117  -0.952  -1.113  -1.083  -0.958
24    R        -0.117  -0.096   0.016  -0.515  -0.480  -0.311  -0.461  -0.433  -0.288
25    K        -0.544  -0.500  -0.459  -0.605  -0.537  -0.466  -0.678  -0.628  -0.560
26    I        -0.970  -0.955  -0.909  -1.004  -0.977  -0.938  -0.895  -0.878  -0.802
27    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    S        -0.544  -0.572  -0.487  -0.606  -0.646  -0.515  -0.678  -0.703  -0.590
56    K        -0.970  -0.955  -0.909  -0.971  -0.938  -0.900  -0.895  -0.878  -0.802
57    T        -0.970  -0.966  -0.890  -0.964  -0.975  -0.844  -0.895  -0.888  -0.784
58    R        -1.397  -1.370  -1.270  -1.347  -1.313  -1.158  -1.113  -1.083  -0.958
59    A        -0.544  -0.483  -0.461  -0.780  -0.687  -0.630  -0.678  -0.610  -0.562
60    L        -0.970  -0.889  -0.878  -1.216  -1.073  -1.089  -0.895  -0.806  -0.772
61    K        -0.548  -0.561  -0.492  -0.737  -0.771  -0.658  -0.669  -0.683  -0.593
62    A        -1.060  -1.043  -0.932  -1.127  -1.112  -0.936  -0.982  -0.960  -0.824
63    V        -0.548  -0.561  -0.492  -0.677  -0.710  -0.612  -0.669  -0.683  -0.593
64    T        -0.548  -0.561  -0.492  -0.627  -0.658  -0.569  -0.669  -0.683  -0.593
65    S        -0.548  -0.535  -0.468  -0.711  -0.707  -0.607  -0.669  -0.652  -0.565
66    I        -0.548  -0.535  -0.468  -0.750  -0.730  -0.631  -0.669  -0.652  -0.565
67    I        -0.548  -0.535  -0.468  -0.843  -0.841  -0.736  -0.669  -0.652  -0.565
68    A        -1.060  -1.043  -0.932  -1.200  -1.184  -1.010  -0.982  -0.960  -0.824
69    D        -1.060  -1.043  -0.932  -1.200  -1.187  -1.010  -0.982  -0.960  -0.824
70    A        -0.970  -0.959  -0.909  -1.161  -1.139  -1.030  -0.895  -0.880  -0.802
71    D        -1.397  -1.377  -1.270  -1.427  -1.423  -1.239  -1.113  -1.089  -0.958
72    E        -0.970  -0.959  -0.909  -0.914  -0.900  -0.849  -0.895  -0.880  -0.802
73    N        -1.316  -1.314  -1.250  -1.171  -1.168  -1.062  -1.046  -1.040  -0.942
74    P        -0.447  -0.410  -0.426  -0.706  -0.657  -0.630  -0.567  -0.522  -0.521
75    Q        -0.812  -0.727  -0.808  -1.034  -0.915  -1.027  -0.727  -0.629  -0.700
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    K        -0.219  -0.315  -0.368  -0.123  -0.261  -0.345  -0.248  -0.373  -0.440
81    K        -1.682  -1.658  -1.556  -1.489  -1.466  -1.302  -1.206  -1.180  -1.053
82    V        -1.316  -1.234  -1.230  -1.177  -1.046  -1.057  -1.046  -0.966  -0.926
83    N        -0.950  -0.942  -0.884  -0.972  -0.956  -0.874  -0.887  -0.872  -0.781
84    N        -1.316  -1.289  -1.225  -1.394  -1.372  -1.267  -1.046  -1.018  -0.921
85    E        -1.682  -1.658  -1.556  -1.352  -1.301  -1.164  -1.206  -1.180  -1.053
86    T        -0.081  -0.079   0.023  -0.243  -0.247  -0.097  -0.408  -0.408  -0.277
87    N        -0.447  -0.429  -0.432  -0.384  -0.376  -0.347  -0.567  -0.555  -0.529
88    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    K        -0.950  -0.986  -0.901  -0.970  -1.006  -0.871  -0.887  -0.911  -0.796
100   R        -0.950  -0.949  -0.871  -0.848  -0.852  -0.737  -0.887  -0.877  -0.770
101   I        -1.316  -1.277  -1.226  -1.310  -1.248  -1.146  -1.046  -1.005  -0.922
102   G        -0.219  -0.185  -0.342  -0.031   0.013  -0.226  -0.248  -0.204  -0.406
103   K        -0.812  -0.841  -0.855  -0.790  -0.826  -0.872  -0.727  -0.757  -0.749
104   F        -0.950  -0.943  -0.872  -1.219  -1.208  -1.077  -0.887  -0.875  -0.770
105   E        -0.812  -0.841  -0.855  -0.553  -0.597  -0.587  -0.727  -0.757  -0.749
106   Y         0.650   0.688   0.782   0.576   0.644   0.775   0.231   0.294   0.412
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   L        -0.848  -0.797  -0.846  -0.758  -0.683  -0.792  -0.787  -0.737  -0.747
111   F        -1.288  -1.300  -1.223  -1.257  -1.248  -1.168  -1.031  -1.033  -0.922
112   Y        -1.168  -1.189  -1.201  -0.964  -1.004  -1.061  -0.909  -0.926  -0.901
113   K        -0.407  -0.471  -0.425  -0.512  -0.623  -0.578  -0.542  -0.599  -0.524
114   F        -0.407  -0.429  -0.392  -0.420  -0.457  -0.411  -0.542  -0.557  -0.490
115   L        -0.407  -0.427  -0.408  -0.728  -0.736  -0.688  -0.542  -0.556  -0.505
116   L         0.553   0.436   0.286   0.439   0.285   0.088   0.557   0.381   0.132
117   V        -0.328  -0.308  -0.388  -0.648  -0.615  -0.732  -0.420  -0.390  -0.474
118   L        -1.288  -1.258  -1.211  -1.385  -1.335  -1.272  -1.031  -1.000  -0.913
119   L         0.249   0.264   0.158  -0.089  -0.070  -0.230   0.069   0.090  -0.084
120   Y        -0.528  -0.550  -0.462  -0.355  -0.371  -0.228  -0.665  -0.679  -0.564
121   I        -1.288  -1.279  -1.222  -1.271  -1.263  -1.205  -1.031  -1.015  -0.921
122   C        -0.848  -0.829  -0.834  -0.795  -0.794  -0.759  -0.787  -0.755  -0.734
123   F        -0.528  -0.544  -0.454  -0.531  -0.531  -0.397  -0.665  -0.671  -0.555
124   G        -0.008   0.049   0.071  -0.131  -0.041  -0.022  -0.298  -0.214  -0.204
125   L        -0.087  -0.085   0.024  -0.645  -0.647  -0.480  -0.420  -0.418  -0.276
126   F        -0.328  -0.267  -0.377  -0.172  -0.078  -0.247  -0.420  -0.341  -0.461
127   R        -0.848  -0.897  -0.862  -0.773  -0.846  -0.793  -0.787  -0.825  -0.759
128   Y        -0.968  -0.999  -0.892  -0.803  -0.835  -0.672  -0.909  -0.924  -0.790
129   G        -0.848  -0.853  -0.828  -0.707  -0.708  -0.675  -0.787  -0.788  -0.730
130   Q        -0.071  -0.123  -0.290   0.269   0.190  -0.078  -0.054  -0.126  -0.340
131   Y        -0.071  -0.139  -0.299   0.293   0.207  -0.010  -0.054  -0.145  -0.350
132   Q        -1.608  -1.527  -1.519  -1.520  -1.380  -1.407  -1.153  -1.081  -1.028
133   Y         0.553   0.488   0.311   0.808   0.717   0.444   0.557   0.457   0.173
134   N        -0.008   0.018   0.054   0.001   0.043   0.088  -0.298  -0.263  -0.231
135   K        -0.071  -0.132  -0.291   0.257   0.178  -0.053  -0.054  -0.138  -0.341
136   M        -0.407  -0.362  -0.387  -0.607  -0.544  -0.564  -0.542  -0.489  -0.485
137   K        -0.968  -0.932  -0.886  -0.886  -0.826  -0.750  -0.909  -0.870  -0.785
138   L        -0.328  -0.401  -0.389  -0.593  -0.670  -0.638  -0.420  -0.497  -0.478
139   R        -0.328  -0.366  -0.373  -0.338  -0.385  -0.397  -0.420  -0.456  -0.458
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   I        -1.288  -1.264  -1.218  -1.463  -1.448  -1.328  -1.031  -1.004  -0.918
144   F         0.553   0.565   0.301   0.421   0.432   0.076   0.557   0.572   0.156
145   S        -0.968  -0.965  -0.879  -0.939  -0.932  -0.798  -0.909  -0.899  -0.780
146   I        -0.328  -0.319  -0.369  -0.557  -0.504  -0.630  -0.420  -0.394  -0.452
147   I        -1.608  -1.622  -1.523  -1.561  -1.619  -1.461  -1.153  -1.156  -1.030
148   Y         0.553   0.505   0.288   0.849   0.792   0.481   0.557   0.485   0.136
149   N        -0.087  -0.044   0.042  -0.118  -0.045   0.082  -0.420  -0.362  -0.251
150   H         0.632   0.656   0.769   0.537   0.574   0.752   0.191   0.226   0.385
151   A        -0.648  -0.623  -0.517  -0.665  -0.619  -0.466  -0.787  -0.756  -0.622
152   Y        -0.968  -0.960  -0.890  -0.872  -0.839  -0.719  -0.909  -0.894  -0.789
153   T         0.112   0.084   0.130   0.021  -0.017   0.063  -0.176  -0.208  -0.139
154   P         1.216   1.149   1.054   1.423   1.340   1.210   1.290   1.175   0.970
155   Q         0.873   0.814   0.843   0.970   0.856   0.860   0.679   0.552   0.542
156   L         1.216   1.258   1.058   1.017   1.074   0.797   1.290   1.357   0.977
157   I         1.911   1.937   2.053   1.848   1.890   2.069   2.146   2.186   2.389
158   R        -0.071  -0.117  -0.315   0.195   0.127  -0.200  -0.054  -0.113  -0.372
159   Q        -1.168  -1.189  -1.201  -0.800  -0.835  -0.866  -0.909  -0.926  -0.901
160   D         1.911   1.937   2.053   1.966   2.006   2.188   2.146   2.186   2.389
161   V         0.553   0.509   0.309   0.680   0.624   0.307   0.557   0.488   0.169
162   I        -0.407  -0.353  -0.396  -0.490  -0.416  -0.468  -0.542  -0.480  -0.492
163   P        -0.328  -0.306  -0.391  -0.365  -0.343  -0.452  -0.420  -0.401  -0.481
164   L         1.911   1.937   2.053   1.654   1.689   1.873   2.146   2.186   2.389
165   K        -0.848  -0.815  -0.839  -0.795  -0.748  -0.756  -0.787  -0.746  -0.739
166   K         1.216   1.177   1.037   1.279   1.238   1.040   1.290   1.223   0.936
167   I         0.112   0.087   0.139  -0.394  -0.421  -0.342  -0.176  -0.191  -0.122
168   P         1.911   1.937   2.053   2.043   2.082   2.266   2.146   2.186   2.389
169   K         0.873   0.858   0.837   0.782   0.757   0.689   0.679   0.639   0.529
170   R        -0.407  -0.377  -0.399  -0.293  -0.241  -0.263  -0.542  -0.501  -0.496
171   L         0.249   0.235   0.192  -0.103  -0.119  -0.205   0.069   0.063  -0.023
172   A         0.112   0.124   0.130   0.030   0.046   0.072  -0.176  -0.157  -0.136
173   A        -0.087  -0.044   0.042  -0.183  -0.134   0.013  -0.420  -0.362  -0.251
174   I         1.911   1.937   2.053   1.848   1.890   2.069   2.146   2.186   2.389
175   L         0.553   0.488   0.311   0.371   0.273  -0.003   0.557   0.457   0.173
176   E         0.112   0.100   0.116  -0.022  -0.026   0.004  -0.176  -0.179  -0.154
177   V        -0.648  -0.635  -0.774  -0.738  -0.712  -0.898  -0.542  -0.527  -0.662
178   K        -0.328  -0.409  -0.392  -0.326  -0.440  -0.414  -0.420  -0.509  -0.481
179   P        -0.087  -0.093   0.019  -0.276  -0.295  -0.124  -0.420  -0.429  -0.283
180   V        -0.648  -0.574  -0.768  -0.483  -0.371  -0.688  -0.542  -0.453  -0.656
181   G        -1.316  -1.330  -1.250  -1.186  -1.214  -1.093  -1.046  -1.052  -0.942
182   D        -0.219  -0.315  -0.368  -0.080  -0.228  -0.323  -0.248  -0.373  -0.440
183   V        -0.447  -0.450  -0.443  -0.551  -0.552  -0.563  -0.567  -0.567  -0.541
184   G         0.807   0.860   0.867   0.770   0.858   0.841   0.550   0.644   0.594
185   G         1.216   1.177   1.037   1.389   1.343   1.141   1.290   1.223   0.936
186   G         1.911   1.937   2.053   2.013   2.052   2.236   2.146   2.186   2.389
187   V        -0.407  -0.425  -0.393  -0.785  -0.827  -0.768  -0.542  -0.554  -0.491
188   T        -1.168  -1.127  -1.167  -0.991  -0.937  -1.003  -0.909  -0.866  -0.870
189   G         1.216   1.177   1.037   1.371   1.323   1.104   1.290   1.223   0.936
190   L         1.911   1.937   2.053   1.654   1.689   1.873   2.146   2.186   2.389
191   L         0.249   0.283   0.184  -0.008   0.056  -0.153   0.069   0.122  -0.039
192   N        -0.328  -0.399  -0.398  -0.200  -0.307  -0.303  -0.420  -0.507  -0.490
193   D        -0.328  -0.326  -0.390  -0.294  -0.302  -0.385  -0.420  -0.423  -0.481
194   A         0.112   0.135   0.131  -0.040   0.005   0.009  -0.176  -0.137  -0.131
195   S         1.216   1.149   1.054   1.367   1.291   1.179   1.290   1.175   0.970
196   E         0.873   0.883   0.839   0.827   0.838   0.717   0.679   0.689   0.533
197   I         0.112   0.162   0.136  -0.340  -0.276  -0.292  -0.176  -0.118  -0.126
198   V        -0.528  -0.553  -0.471  -0.609  -0.644  -0.516  -0.665  -0.683  -0.574
199   C         0.690   0.734   0.804   0.672   0.737   0.845   0.313   0.390   0.459
200   W         1.911   1.937   2.053   2.229   2.267   2.454   2.146   2.186   2.389
201   T        -0.087  -0.041   0.044  -0.140  -0.054   0.064  -0.420  -0.359  -0.249
202   V        -0.648  -0.618  -0.793  -0.402  -0.357  -0.595  -0.542  -0.506  -0.683
203   S        -0.328  -0.303  -0.368  -0.276  -0.237  -0.347  -0.420  -0.403  -0.455
204   A         0.553   0.488   0.311   0.791   0.696   0.434   0.557   0.457   0.173
205   G        -0.071  -0.185  -0.308   0.179   0.016  -0.179  -0.054  -0.203  -0.363
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   I         1.216   1.258   1.058   1.171   1.236   0.905   1.290   1.357   0.977
208   K        -0.328  -0.360  -0.391  -0.324  -0.366  -0.400  -0.420  -0.455  -0.481
209   H        -0.848  -0.844  -0.853  -0.637  -0.646  -0.668  -0.787  -0.784  -0.753
210   L         1.216   1.225   1.056   1.017   1.032   0.793   1.290   1.303   0.972
211   M        -0.328  -0.313  -0.364  -0.320  -0.289  -0.361  -0.420  -0.394  -0.446
212   L         0.112   0.142   0.129  -0.340  -0.277  -0.300  -0.176  -0.128  -0.134
213   Y         1.911   1.937   2.053   2.064   2.106   2.288   2.146   2.186   2.389
214   D         0.690   0.734   0.804   0.483   0.560   0.645   0.313   0.390   0.459
215   Y        -0.328  -0.370  -0.391  -0.185  -0.264  -0.287  -0.420  -0.477  -0.482
216   D        -0.328  -0.347  -0.380  -0.278  -0.292  -0.362  -0.420  -0.429  -0.462
217   G         1.911   1.937   2.053   2.013   2.052   2.236   2.146   2.186   2.389
218   I        -1.608  -1.624  -1.522  -1.535  -1.543  -1.399  -1.153  -1.157  -1.030
219   L         0.553   0.676   0.332   0.435   0.593   0.148   0.557   0.738   0.206
220   Q        -0.328  -0.260  -0.356  -0.331  -0.222  -0.368  -0.420  -0.322  -0.436
221   R        -1.608  -1.571  -1.516  -1.253  -1.207  -1.120  -1.153  -1.117  -1.025
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   N        -0.071  -0.123  -0.290   0.231   0.154  -0.089  -0.054  -0.126  -0.340
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   V        -0.528  -0.556  -0.471  -0.882  -0.922  -0.823  -0.665  -0.686  -0.576
228   P        -1.168  -1.175  -1.163  -0.941  -0.967  -0.955  -0.909  -0.912  -0.867
229   E        -0.328  -0.409  -0.392  -0.288  -0.403  -0.379  -0.420  -0.509  -0.481
230   L         0.112   0.107   0.122  -0.279  -0.277  -0.212  -0.176  -0.189  -0.149
231   R        -0.648  -0.694  -0.776  -0.280  -0.361  -0.452  -0.542  -0.594  -0.665
232   M        -0.328  -0.240  -0.362  -0.280  -0.167  -0.299  -0.420  -0.316  -0.446
233   E        -1.288  -1.255  -1.220  -1.226  -1.186  -1.146  -1.031  -0.996  -0.919
234   I         0.249   0.210   0.148   0.156   0.110   0.014   0.069   0.014  -0.098
235   H        -0.848  -0.854  -0.849  -0.647  -0.666  -0.664  -0.787  -0.792  -0.750
236   S        -0.968  -0.973  -0.888  -0.927  -0.925  -0.787  -0.909  -0.903  -0.786
237   N        -0.848  -0.845  -0.825  -0.775  -0.756  -0.715  -0.787  -0.771  -0.725
238   L         1.216   1.234   1.047   1.057   1.084   0.861   1.290   1.319   0.955
239   A        -0.648  -0.638  -0.770  -0.386  -0.377  -0.588  -0.542  -0.530  -0.659
240   K        -1.168  -1.189  -1.201  -1.136  -1.161  -1.217  -0.909  -0.926  -0.901
241   Y         1.911   1.937   2.053   2.064   2.106   2.288   2.146   2.186   2.389
242   F         0.249   0.188   0.170   0.345   0.240   0.169   0.069  -0.017  -0.065
243   G         1.911   1.937   2.053   2.013   2.052   2.236   2.146   2.186   2.389
244   P        -0.848  -0.839  -0.834  -0.817  -0.792  -0.822  -0.787  -0.768  -0.731
245   A        -0.848  -0.852  -0.849  -0.751  -0.763  -0.731  -0.787  -0.790  -0.749
246   H        -0.548  -0.527  -0.479  -0.515  -0.488  -0.410  -0.669  -0.642  -0.578
247   V        -0.848  -0.894  -0.847  -0.887  -0.945  -0.855  -0.787  -0.821  -0.745
248   P         1.216   1.149   1.054   1.446   1.368   1.256   1.290   1.175   0.970
249   N        -1.288  -1.233  -1.210  -1.207  -1.123  -1.089  -1.031  -0.981  -0.912
250   Y        -0.328  -0.358  -0.385  -0.237  -0.305  -0.351  -0.420  -0.462  -0.474
251   A        -1.288  -1.326  -1.240  -1.140  -1.187  -1.056  -1.031  -1.051  -0.935
252   V         0.690   0.697   0.791   0.362   0.368   0.501   0.313   0.312   0.432
253   K        -0.407  -0.440  -0.413  -0.459  -0.497  -0.441  -0.542  -0.569  -0.511
254   I        -0.328  -0.419  -0.399  -0.413  -0.536  -0.506  -0.420  -0.523  -0.490
255   P         1.911   1.937   2.053   2.043   2.082   2.266   2.146   2.186   2.389
256   H         1.216   1.149   1.054   1.542   1.459   1.349   1.290   1.175   0.970
257   S        -0.648  -0.639  -0.760  -0.507  -0.490  -0.708  -0.542  -0.529  -0.647
258   N        -0.328  -0.369  -0.399  -0.175  -0.249  -0.272  -0.420  -0.481  -0.490
259   K        -1.316  -1.309  -1.242  -1.348  -1.348  -1.242  -1.046  -1.035  -0.935
260   I        -0.447  -0.502  -0.432  -0.548  -0.607  -0.494  -0.567  -0.623  -0.529
261   F        -0.544  -0.565  -0.487  -0.558  -0.582  -0.448  -0.678  -0.695  -0.590
262   Y         0.157   0.126   0.125   0.272   0.217   0.203  -0.044  -0.097  -0.121
263   N        -0.548  -0.554  -0.492  -0.655  -0.666  -0.585  -0.669  -0.676  -0.593
264   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   E         1.911   1.937   2.053   1.975   2.015   2.198   2.146   2.186   2.389
269   T        -0.037  -0.041   0.060  -0.197  -0.207  -0.051  -0.357  -0.361  -0.227
270   E        -1.060  -1.035  -0.932  -1.052  -1.013  -0.860  -0.982  -0.953  -0.824
271   T        -1.060  -1.035  -0.932  -1.135  -1.094  -0.944  -0.982  -0.953  -0.824
272   D        -0.037  -0.048   0.056  -0.287  -0.296  -0.148  -0.357  -0.368  -0.233
273   V         0.669   0.681   0.775   0.218   0.223   0.337   0.269   0.279   0.398
274   G        -0.548  -0.564  -0.482  -0.658  -0.701  -0.577  -0.669  -0.688  -0.581
275   N        -0.548  -0.536  -0.468  -0.539  -0.524  -0.433  -0.669  -0.654  -0.565
276   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   E        -0.544  -0.522  -0.470  -0.669  -0.641  -0.556  -0.678  -0.652  -0.571
279   A        -0.970  -0.982  -0.909  -0.926  -0.950  -0.847  -0.895  -0.903  -0.802
280   N        -1.316  -1.280  -1.223  -1.284  -1.228  -1.154  -1.046  -1.009  -0.920
281   Q        -1.316  -1.328  -1.233  -1.175  -1.196  -1.072  -1.046  -1.051  -0.928
282   E        -0.968  -0.966  -0.883  -0.886  -0.873  -0.746  -0.909  -0.898  -0.783
283   K        -1.288  -1.273  -1.226  -1.258  -1.224  -1.149  -1.031  -1.011  -0.924
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   D        -1.288  -1.258  -1.212  -1.128  -1.095  -1.006  -1.031  -1.000  -0.914
291   K        -0.648  -0.677  -0.785  -0.505  -0.545  -0.709  -0.542  -0.576  -0.675
292   I        -0.848  -0.848  -0.830  -0.921  -0.902  -0.897  -0.787  -0.774  -0.730
293   A        -0.328  -0.328  -0.386  -0.263  -0.248  -0.334  -0.420  -0.404  -0.469
294   I         0.249   0.325   0.183  -0.124  -0.013  -0.240   0.069   0.177  -0.040
295   E        -0.071  -0.178  -0.305   0.102  -0.062  -0.273  -0.054  -0.194  -0.358
296   I         0.873   0.814   0.843   0.699   0.591   0.602   0.679   0.552   0.542
297   S        -0.328  -0.370  -0.391  -0.202  -0.261  -0.266  -0.420  -0.477  -0.482
298   L         1.216   1.177   1.037   1.003   0.950   0.730   1.290   1.223   0.936
299   L         0.873   0.854   0.852   0.475   0.431   0.387   0.679   0.631   0.561
300   S         1.216   1.149   1.054   1.342   1.259   1.127   1.290   1.175   0.970
301   N        -0.848  -0.808  -0.827  -0.807  -0.759  -0.757  -0.787  -0.748  -0.729
302   R        -0.848  -0.760  -0.827  -0.841  -0.697  -0.785  -0.787  -0.687  -0.725
303   D         1.911   1.937   2.053   1.966   2.006   2.188   2.146   2.186   2.389
304   G         1.911   1.937   2.053   2.013   2.052   2.236   2.146   2.186   2.389
305   R         0.873   0.943   0.899   0.888   1.004   0.887   0.679   0.804   0.659
306   E        -0.528  -0.487  -0.446  -0.634  -0.567  -0.513  -0.665  -0.608  -0.545
307   T        -0.071  -0.178  -0.305   0.216   0.062  -0.117  -0.054  -0.194  -0.358
308   I         0.873   0.903   0.856   0.604   0.655   0.481   0.679   0.727   0.569
309   V         0.249   0.291   0.186   0.107   0.165  -0.059   0.069   0.117  -0.040
310   D         0.632   0.656   0.769   0.360   0.397   0.571   0.191   0.226   0.385
311   L         1.911   1.937   2.053   1.654   1.689   1.873   2.146   2.186   2.389
312   T         1.216   1.225   1.056   1.409   1.430   1.206   1.290   1.303   0.972
313   K         1.216   1.149   1.054   1.279   1.200   1.068   1.290   1.175   0.970
314   T         0.553   0.550   0.321   0.772   0.769   0.431   0.557   0.547   0.188
315   M         0.112   0.107   0.122  -0.032  -0.094  -0.056  -0.176  -0.189  -0.149
316   A         0.112   0.179   0.135   0.071   0.148   0.137  -0.176  -0.097  -0.132
317   E         0.632   0.657   0.769   0.360   0.399   0.570   0.191   0.228   0.385
318   L         1.216   1.177   1.037   1.057   1.013   0.848   1.290   1.223   0.936
319   C        -0.407  -0.430  -0.417  -0.278  -0.310  -0.290  -0.542  -0.559  -0.516
320   A        -1.288  -1.326  -1.240  -1.189  -1.237  -1.113  -1.031  -1.051  -0.935
321   V        -0.848  -0.818  -0.839  -0.811  -0.761  -0.781  -0.787  -0.747  -0.736
322   N        -0.328  -0.266  -0.365  -0.331  -0.248  -0.372  -0.420  -0.348  -0.451
323   E        -0.328  -0.363  -0.389  -0.325  -0.397  -0.422  -0.420  -0.467  -0.478
324   L         0.690   0.674   0.774   0.132   0.091   0.241   0.313   0.265   0.396
325   S         0.249   0.277   0.172   0.232   0.283   0.100   0.069   0.114  -0.062
326   V        -0.968  -0.968  -0.889  -1.084  -1.066  -0.939  -0.909  -0.898  -0.787
327   S        -0.848  -0.815  -0.830  -0.794  -0.746  -0.766  -0.787  -0.751  -0.730
328   D         1.216   1.149   1.054   1.356   1.277   1.153   1.290   1.175   0.970
329   I         0.249   0.234   0.173   0.049   0.020  -0.124   0.069   0.040  -0.061
330   T         1.216   1.284   1.058   1.389   1.484   1.168   1.290   1.398   0.977
331   M        -0.848  -0.850  -0.840  -0.880  -0.908  -0.884  -0.787  -0.782  -0.739
332   D         0.112   0.146   0.128  -0.048  -0.016  -0.023  -0.176  -0.147  -0.143
333   L         1.216   1.234   1.047   1.017   1.044   0.778   1.290   1.319   0.955
334   V         0.112   0.126   0.125  -0.214  -0.191  -0.216  -0.176  -0.153  -0.145
335   D         0.873   0.912   0.877   0.847   0.911   0.824   0.679   0.744   0.613
336   S        -1.168  -1.187  -1.198  -0.968  -1.014  -1.022  -0.909  -0.924  -0.898
337   E         0.873   0.885   0.848   0.877   0.893   0.813   0.679   0.691   0.552
338   L         1.216   1.234   1.047   1.057   1.084   0.861   1.290   1.319   0.955
339   K        -1.288  -1.272  -1.210  -1.277  -1.252  -1.138  -1.031  -1.010  -0.912
340   Q         0.249   0.313   0.198   0.339   0.440   0.293   0.069   0.174  -0.014
341   L         0.873   0.814   0.843   0.515   0.406   0.433   0.679   0.552   0.542
342   V         1.911   1.937   2.053   1.946   1.987   2.169   2.146   2.186   2.389
343   G        -0.071  -0.178  -0.305   0.165   0.007  -0.197  -0.054  -0.194  -0.358
344   P        -1.168  -1.134  -1.166  -0.849  -0.804  -0.846  -0.909  -0.872  -0.869
345   E         1.911   1.937   2.053   1.972   2.010   2.195   2.146   2.186   2.389
346   P         1.911   1.937   2.053   2.043   2.082   2.266   2.146   2.186   2.389
347   D         1.216   1.234   1.047   1.334   1.365   1.096   1.290   1.319   0.955
348   L         1.911   1.937   2.053   1.654   1.689   1.873   2.146   2.186   2.389
349   L         1.216   1.225   1.056   1.003   1.016   0.762   1.290   1.303   0.972
350   L         0.632   0.652   0.767   0.034   0.064   0.236   0.191   0.218   0.381
351   Y        -1.608  -1.603  -1.520  -1.387  -1.430  -1.287  -1.153  -1.142  -1.028
352   F         1.911   1.937   2.053   2.108   2.149   2.332   2.146   2.186   2.389
353   G         0.873   0.854   0.852   0.889   0.849   0.816   0.679   0.631   0.561
354   P         1.911   1.937   2.053   2.043   2.082   2.266   2.146   2.186   2.389
355   S        -0.848  -0.869  -0.840  -0.812  -0.873  -0.805  -0.787  -0.807  -0.741
356   L         1.216   1.177   1.037   1.017   0.967   0.763   1.290   1.223   0.936
357   D        -0.071  -0.159  -0.299   0.103  -0.031  -0.259  -0.054  -0.171  -0.351
358   L         1.911   1.937   2.053   1.654   1.689   1.873   2.146   2.186   2.389
359   Q        -0.071  -0.098  -0.289   0.259   0.219  -0.093  -0.054  -0.089  -0.338
360   G         0.873   0.943   0.899   0.866   0.981   0.873   0.679   0.804   0.659
361   F         0.632   0.652   0.768   0.530   0.561   0.738   0.191   0.218   0.382
362   P         1.911   1.937   2.053   2.043   2.082   2.266   2.146   2.186   2.389
363   P         1.911   1.937   2.053   2.043   2.082   2.266   2.146   2.186   2.389
364   W         1.911   1.937   2.053   2.229   2.267   2.454   2.146   2.186   2.389
365   H         0.690   0.676   0.777   0.710   0.667   0.821   0.313   0.268   0.401
366   I         0.553   0.436   0.286   0.536   0.361   0.083   0.557   0.381   0.132
367   R         1.911   1.937   2.053   2.058   2.095   2.281   2.146   2.186   2.389
368   L         1.911   1.937   2.053   1.654   1.689   1.873   2.146   2.186   2.389
369   T        -0.328  -0.353  -0.369  -0.210  -0.221  -0.242  -0.420  -0.436  -0.449
370   E         1.911   1.937   2.053   1.972   2.010   2.195   2.146   2.186   2.389
371   F        -0.071   0.018  -0.279  -0.002   0.130  -0.315  -0.054   0.065  -0.325
372   Y        -0.328  -0.374  -0.383  -0.142  -0.210  -0.215  -0.420  -0.473  -0.471
373   W         0.690   0.676   0.777   0.796   0.750   0.903   0.313   0.268   0.401
374   E        -0.071  -0.178  -0.305   0.132  -0.028  -0.222  -0.054  -0.194  -0.358
375   K        -1.168  -1.100  -1.166  -0.891  -0.776  -0.898  -0.909  -0.839  -0.869
376   D         1.216   1.149   1.054   1.317   1.229   1.073   1.290   1.175   0.970
377   N         1.216   1.149   1.054   1.372   1.282   1.100   1.290   1.175   0.970
378   N        -1.288  -1.292  -1.219  -1.139  -1.142  -1.029  -1.031  -1.027  -0.919
379   E        -1.288  -1.307  -1.234  -1.143  -1.171  -1.038  -1.031  -1.037  -0.931
380   V         1.216   1.149   1.054   1.322   1.240   1.105   1.290   1.175   0.970
381   I        -0.648  -0.574  -0.768  -0.500  -0.377  -0.758  -0.542  -0.453  -0.656
382   Y         1.911   1.937   2.053   2.064   2.106   2.288   2.146   2.186   2.389
383   S        -1.288  -1.305  -1.212  -1.209  -1.258  -1.096  -1.031  -1.036  -0.913
384   V         0.553   0.550   0.321   0.680   0.680   0.327   0.557   0.547   0.188
385   F         1.911   1.937   2.053   2.108   2.149   2.332   2.146   2.186   2.389
386   I        -0.328  -0.409  -0.392  -0.527  -0.634  -0.629  -0.420  -0.509  -0.481
387   R         0.873   0.842   0.851   0.888   0.821   0.788   0.679   0.608   0.560
388   G         0.690   0.701   0.788   0.557   0.566   0.691   0.313   0.322   0.425
389   L         1.911   1.937   2.053   1.654   1.689   1.873   2.146   2.186   2.389
390   R        -0.848  -0.880  -0.856  -0.768  -0.839  -0.836  -0.787  -0.812  -0.755
391   Q        -0.848  -0.889  -0.841  -0.681  -0.739  -0.675  -0.787  -0.821  -0.742
392   Y         0.873   0.903   0.856   0.961   1.009   0.903   0.679   0.727   0.569
393   A         0.632   0.652   0.768   0.407   0.433   0.616   0.191   0.219   0.381
394   G        -0.528  -0.492  -0.467  -0.575  -0.524  -0.490  -0.665  -0.626  -0.572
395   C         0.690   0.674   0.774   0.732   0.677   0.822   0.313   0.265   0.396
396   K         0.553   0.436   0.286   0.670   0.516   0.293   0.557   0.381   0.132
397   V        -0.328  -0.254  -0.365  -0.121   0.018  -0.198  -0.420  -0.313  -0.448
398   N         0.873   0.814   0.843   0.928   0.826   0.839   0.679   0.552   0.542
399   V        -0.071  -0.159  -0.299   0.049  -0.089  -0.335  -0.054  -0.171  -0.351
400   G         1.911   1.937   2.053   2.013   2.052   2.236   2.146   2.186   2.389
401   K         0.553   0.436   0.286   0.688   0.537   0.327   0.557   0.381   0.132
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12063
Output conservation file - output/Q12063
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
