1     M         1.789   1.793   1.841   2.000   2.008   2.087   1.955   1.962   2.032
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     N        -1.665  -1.659  -1.604  -1.471  -1.458  -1.378  -1.219  -1.211  -1.131
4     V        -1.665  -1.659  -1.604  -1.358  -1.347  -1.266  -1.219  -1.211  -1.131
5     C        -1.070  -1.097  -1.079  -0.983  -1.032  -1.014  -0.901  -0.927  -0.887
6     K        -0.475  -0.490  -0.454  -0.466  -0.488  -0.424  -0.584  -0.598  -0.539
7     L        -0.250  -0.239  -0.347  -0.105  -0.087  -0.259  -0.266  -0.251  -0.390
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     K        -1.186  -1.179  -1.126  -1.259  -1.248  -1.167  -1.020  -1.011  -0.934
10    E        -0.442  -0.425  -0.428  -0.439  -0.415  -0.420  -0.524  -0.500  -0.498
11    I        -1.186  -1.179  -1.126  -1.078  -1.061  -0.985  -1.020  -1.011  -0.934
12    V        -1.186  -1.179  -1.126  -1.033  -1.024  -0.941  -1.020  -1.011  -0.934
13    -        -0.569  -0.565  -0.511  -0.762  -0.752  -0.670  -0.690  -0.683  -0.604
14    -        -1.186  -1.179  -1.126  -1.155  -1.143  -1.063  -1.020  -1.011  -0.934
15    P        -1.070  -1.081  -1.065  -1.004  -1.024  -0.992  -0.901  -0.911  -0.872
16    L         1.789   1.793   1.841   1.854   1.863   1.941   1.955   1.962   2.032
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    F        -0.250  -0.283  -0.374   0.012  -0.034  -0.164  -0.266  -0.310  -0.426
20    P        -1.665  -1.659  -1.604  -1.601  -1.593  -1.508  -1.219  -1.211  -1.131
21    R         0.715   0.702   0.557   0.825   0.809   0.591   0.686   0.665   0.412
22    S         0.423   0.371   0.411   0.173   0.096   0.151   0.192   0.098   0.154
23    S        -0.250  -0.291  -0.370  -0.259  -0.314  -0.436  -0.266  -0.320  -0.421
24    F        -1.070  -1.097  -1.079  -0.776  -0.813  -0.783  -0.901  -0.927  -0.887
25    T        -0.250  -0.266  -0.369  -0.134  -0.161  -0.342  -0.266  -0.286  -0.419
26    D        -0.250  -0.291  -0.370  -0.178  -0.243  -0.376  -0.266  -0.320  -0.421
27    G        -0.475  -0.478  -0.458  -0.593  -0.596  -0.567  -0.584  -0.584  -0.543
28    V         0.715   0.702   0.557   0.799   0.782   0.557   0.686   0.665   0.412
29    V        -1.070  -1.035  -1.052  -0.889  -0.834  -0.862  -0.901  -0.862  -0.859
30    S        -0.250  -0.265  -0.341  -0.312  -0.333  -0.458  -0.266  -0.285  -0.381
31    T         1.789   1.793   1.841   1.876   1.882   1.963   1.955   1.962   2.032
32    G         0.344   0.335   0.366   0.168   0.148   0.192   0.051   0.033   0.071
33    K        -1.070  -1.097  -1.079  -0.902  -0.946  -0.918  -0.901  -0.927  -0.887
34    S         0.344   0.342   0.370   0.071   0.065   0.108   0.051   0.045   0.077
35    F         1.789   1.793   1.841   1.892   1.900   1.979   1.955   1.962   2.032
36    R         0.715   0.769   0.586   0.845   0.923   0.654   0.686   0.772   0.462
37    S         1.789   1.793   1.841   1.680   1.692   1.768   1.955   1.962   2.032
38    W         1.789   1.793   1.841   2.043   2.051   2.130   1.955   1.962   2.032
39    D         1.789   1.793   1.841   1.804   1.811   1.891   1.955   1.962   2.032
40    T         1.789   1.793   1.841   1.876   1.882   1.963   1.955   1.962   2.032
41    C         1.789   1.793   1.841   1.870   1.878   1.957   1.955   1.962   2.032
42    M         1.789   1.793   1.841   2.000   2.008   2.087   1.955   1.962   2.032
43    D         0.715   0.736   0.585   0.850   0.877   0.685   0.686   0.718   0.461
44    N         1.789   1.793   1.841   1.697   1.708   1.785   1.955   1.962   2.032
45    K         0.715   0.702   0.557   0.857   0.841   0.625   0.686   0.665   0.412
46    A        -0.250  -0.266  -0.369  -0.120  -0.146  -0.292  -0.266  -0.286  -0.419
47    C         1.789   1.793   1.841   1.870   1.878   1.957   1.955   1.962   2.032
48    K         1.789   1.793   1.841   1.854   1.863   1.941   1.955   1.962   2.032
49    I         1.789   1.793   1.841   1.843   1.853   1.930   1.955   1.962   2.032
50    I         0.715   0.702   0.557   0.831   0.816   0.592   0.686   0.665   0.412
51    A         1.789   1.793   1.841   1.793   1.797   1.880   1.955   1.962   2.032
52    I         1.789   1.793   1.841   1.843   1.853   1.930   1.955   1.962   2.032
53    V         1.789   1.793   1.841   1.815   1.825   1.902   1.955   1.962   2.032
54    G         1.789   1.793   1.841   1.793   1.803   1.880   1.955   1.962   2.032
55    I         1.789   1.793   1.841   1.843   1.853   1.930   1.955   1.962   2.032
56    V         1.789   1.793   1.841   1.815   1.825   1.902   1.955   1.962   2.032
57    L         0.715   0.736   0.585   0.849   0.880   0.659   0.686   0.718   0.461
58    A         0.715   0.702   0.557   0.777   0.756   0.536   0.686   0.665   0.412
59    C        -0.250  -0.220  -0.352  -0.259  -0.213  -0.408  -0.266  -0.225  -0.396
60    I        -0.250  -0.266  -0.369  -0.047  -0.066  -0.214  -0.266  -0.286  -0.419
61    L        -1.070  -1.081  -1.065  -0.882  -0.897  -0.874  -0.901  -0.911  -0.872
62    V        -0.475  -0.475  -0.457  -0.518  -0.520  -0.479  -0.584  -0.581  -0.543
63    I        -0.250  -0.247  -0.358  -0.105  -0.097  -0.274  -0.266  -0.261  -0.405
64    W         0.715   0.679   0.571   1.012   0.958   0.780   0.686   0.628   0.436
65    L        -0.250  -0.266  -0.369  -0.098  -0.120  -0.286  -0.266  -0.286  -0.419
66    I         0.344   0.342   0.370   0.245   0.240   0.277   0.051   0.045   0.077
67    G        -0.250  -0.266  -0.369  -0.186  -0.207  -0.380  -0.266  -0.286  -0.419
68    G        -0.250  -0.266  -0.369  -0.151  -0.175  -0.334  -0.266  -0.286  -0.419
69    L        -0.250  -0.291  -0.370  -0.082  -0.143  -0.268  -0.266  -0.320  -0.421
70    L        -0.250  -0.266  -0.369  -0.074  -0.095  -0.254  -0.266  -0.286  -0.419
71    T        -1.665  -1.659  -1.604  -1.536  -1.532  -1.444  -1.219  -1.211  -1.131
72    C         0.715   0.679   0.571   0.877   0.828   0.669   0.686   0.628   0.436
73    F        -0.250  -0.266  -0.369  -0.045  -0.068  -0.230  -0.266  -0.286  -0.419
74    R        -1.665  -1.659  -1.604  -1.355  -1.348  -1.263  -1.219  -1.211  -1.131
75    Q        -1.665  -1.659  -1.604  -1.473  -1.468  -1.381  -1.219  -1.211  -1.131
76    G         1.789   1.793   1.841   1.793   1.803   1.880   1.955   1.962   2.032
77    V         0.715   0.712   0.558   0.814   0.812   0.583   0.686   0.680   0.414
78    T         0.344   0.348   0.371   0.176   0.182   0.196   0.051   0.057   0.079
79    G        -1.070  -1.097  -1.079  -1.009  -1.055  -1.028  -0.901  -0.927  -0.887
80    I        -0.250  -0.266  -0.369  -0.081  -0.101  -0.259  -0.266  -0.286  -0.419
81    G        -1.070  -1.097  -1.079  -0.981  -1.021  -0.996  -0.901  -0.927  -0.887
82    Q        -1.070  -1.053  -1.068  -0.970  -0.944  -0.980  -0.901  -0.881  -0.876
83    F        -0.250  -0.266  -0.369  -0.042  -0.065  -0.226  -0.266  -0.286  -0.419
84    I        -0.250  -0.238  -0.331  -0.059  -0.041  -0.179  -0.266  -0.251  -0.368
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    C         0.715   0.712   0.558   0.904   0.900   0.690   0.686   0.680   0.414
88    W        -0.250  -0.266  -0.369   0.047   0.021  -0.165  -0.266  -0.286  -0.419
89    C         1.789   1.793   1.841   1.870   1.878   1.957   1.955   1.962   2.032
90    C         1.789   1.793   1.841   1.870   1.878   1.957   1.955   1.962   2.032
91    R        -0.475  -0.462  -0.451  -0.571  -0.553  -0.534  -0.584  -0.567  -0.535
92    C        -0.250  -0.239  -0.347  -0.101  -0.086  -0.260  -0.266  -0.251  -0.390
93    S        -1.070  -1.064  -1.059  -0.983  -0.972  -0.978  -0.901  -0.893  -0.866
94    N         0.423   0.398   0.411   0.204   0.167   0.186   0.192   0.147   0.154
95    D         0.423   0.450   0.422   0.372   0.418   0.357   0.192   0.239   0.173
96    R        -0.569  -0.563  -0.511  -0.894  -0.887  -0.803  -0.690  -0.681  -0.604
97    N        -0.569  -0.563  -0.511  -0.758  -0.742  -0.666  -0.690  -0.681  -0.604
98    G        -0.569  -0.563  -0.511  -0.804  -0.793  -0.713  -0.690  -0.681  -0.604
99    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   P         0.423   0.435   0.420   0.289   0.309   0.271   0.192   0.213   0.170
104   V        -1.186  -1.177  -1.126  -1.060  -1.042  -0.968  -1.020  -1.009  -0.934
105   N         1.789   1.793   1.841   1.639   1.649   1.727   1.955   1.962   2.032
106   E        -0.442  -0.452  -0.446  -0.444  -0.464  -0.455  -0.524  -0.538  -0.521
107   G        -0.442  -0.452  -0.446  -0.587  -0.598  -0.587  -0.524  -0.538  -0.521
108   F        -0.442  -0.477  -0.457  -0.389  -0.449  -0.425  -0.524  -0.569  -0.536
109   S        -0.250  -0.238  -0.331  -0.293  -0.270  -0.423  -0.266  -0.251  -0.368
110   R        -0.250  -0.265  -0.341  -0.110  -0.132  -0.247  -0.266  -0.285  -0.381
111   V        -0.475  -0.478  -0.458  -0.495  -0.497  -0.457  -0.584  -0.584  -0.543
112   N        -1.665  -1.659  -1.604  -1.575  -1.563  -1.482  -1.219  -1.211  -1.131
113   M        -1.070  -1.064  -1.059  -0.970  -0.967  -0.941  -0.901  -0.893  -0.866
114   G        -0.442  -0.407  -0.457  -0.454  -0.400  -0.479  -0.524  -0.475  -0.536
115   -        -0.569  -0.565  -0.511  -0.574  -0.569  -0.483  -0.690  -0.684  -0.604
116   -        -0.569  -0.565  -0.511  -0.561  -0.555  -0.470  -0.690  -0.684  -0.604
117   V        -0.442  -0.407  -0.457  -0.437  -0.379  -0.466  -0.524  -0.475  -0.536
118   A        -0.442  -0.442  -0.442  -0.485  -0.482  -0.491  -0.524  -0.523  -0.516
119   P        -0.442  -0.443  -0.443  -0.582  -0.585  -0.598  -0.524  -0.524  -0.517
120   P        -0.250  -0.266  -0.369  -0.239  -0.267  -0.432  -0.266  -0.286  -0.419
121   S        -1.070  -1.053  -1.068  -1.132  -1.104  -1.140  -0.901  -0.881  -0.876
122   T        -1.070  -1.052  -1.063  -0.954  -0.926  -0.929  -0.901  -0.880  -0.871
123   V         0.344   0.342   0.370   0.158   0.151   0.184   0.051   0.045   0.077
124   I        -1.070  -1.053  -1.068  -1.002  -0.977  -1.007  -0.901  -0.881  -0.876
125   Y         0.344   0.342   0.370   0.249   0.243   0.298   0.051   0.045   0.077
126   Q         0.344   0.342   0.370   0.171   0.160   0.196   0.051   0.045   0.077
127   P         1.789   1.793   1.841   1.742   1.749   1.830   1.955   1.962   2.032
128   I        -0.250  -0.266  -0.369  -0.105  -0.128  -0.291  -0.266  -0.286  -0.419
129   Q        -1.665  -1.659  -1.604  -1.451  -1.449  -1.358  -1.219  -1.211  -1.131
130   Q        -1.665  -1.659  -1.604  -1.451  -1.452  -1.358  -1.219  -1.211  -1.131
131   P         1.789   1.793   1.841   1.742   1.749   1.830   1.955   1.962   2.032
132   E        -1.070  -1.097  -1.079  -0.849  -0.894  -0.862  -0.901  -0.927  -0.887
133   S        -1.186  -1.177  -1.126  -1.244  -1.220  -1.151  -1.020  -1.009  -0.934
134   A         0.582   0.591   0.487   0.587   0.591   0.427   0.467   0.481   0.290
135   Y         1.789   1.793   1.841   1.748   1.754   1.836   1.955   1.962   2.032
136   Y        -1.070  -1.064  -1.059  -1.100  -1.091  -1.084  -0.901  -0.893  -0.866
137   R        -0.569  -0.563  -0.511  -0.654  -0.647  -0.563  -0.690  -0.681  -0.604
138   N        -0.569  -0.563  -0.511  -0.735  -0.725  -0.644  -0.690  -0.681  -0.604
139   D         0.423   0.398   0.411   0.316   0.268   0.285   0.192   0.147   0.154
140   A         0.423   0.398   0.411   0.382   0.334   0.344   0.192   0.147   0.154
141   K         0.423   0.450   0.422   0.319   0.362   0.313   0.192   0.239   0.173
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   N        -0.569  -0.563  -0.511  -0.753  -0.743  -0.662  -0.690  -0.681  -0.604
153   D        -0.569  -0.563  -0.511  -0.909  -0.903  -0.817  -0.690  -0.681  -0.604
154   T         0.423   0.398   0.411   0.398   0.353   0.370   0.192   0.147   0.154
155   F         0.423   0.435   0.420   0.434   0.456   0.415   0.192   0.213   0.170
156   Y         1.789   1.793   1.841   1.767   1.773   1.855   1.955   1.962   2.032
157   D         1.789   1.793   1.841   1.789   1.794   1.876   1.955   1.962   2.032
158   E         1.789   1.793   1.841   1.825   1.835   1.913   1.955   1.962   2.032
159   V        -0.569  -0.563  -0.511  -0.776  -0.763  -0.685  -0.690  -0.681  -0.604
160   K        -0.569  -0.563  -0.511  -0.563  -0.553  -0.471  -0.690  -0.681  -0.604
161   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   E         0.423   0.398   0.411   0.339   0.293   0.304   0.192   0.147   0.154
169   L         1.789   1.793   1.841   1.890   1.898   1.977   1.955   1.962   2.032
170   E         0.423   0.435   0.420   0.272   0.299   0.243   0.192   0.213   0.170
171   E        -0.569  -0.563  -0.511  -0.672  -0.667  -0.581  -0.690  -0.681  -0.604
172   D        -0.569  -0.563  -0.511  -0.800  -0.798  -0.708  -0.690  -0.681  -0.604
173   F         0.423   0.435   0.420   0.408   0.429   0.385   0.192   0.213   0.170
174   D         1.789   1.793   1.841   1.789   1.794   1.876   1.955   1.962   2.032
175   L         1.789   1.793   1.841   1.890   1.898   1.977   1.955   1.962   2.032
176   E         1.789   1.793   1.841   1.825   1.835   1.913   1.955   1.962   2.032
177   K        -0.569  -0.563  -0.511  -0.712  -0.701  -0.621  -0.690  -0.681  -0.604
178   Q         1.789   1.793   1.841   1.811   1.817   1.898   1.955   1.962   2.032
179   K        -0.569  -0.563  -0.511  -0.740  -0.729  -0.648  -0.690  -0.681  -0.604
180   E        -0.569  -0.563  -0.511  -0.712  -0.708  -0.621  -0.690  -0.681  -0.604
181   K        -0.569  -0.563  -0.511  -0.654  -0.651  -0.563  -0.690  -0.681  -0.604
182   T        -0.569  -0.563  -0.511  -0.516  -0.500  -0.425  -0.690  -0.681  -0.604
183   R         0.423   0.398   0.411   0.359   0.316   0.332   0.192   0.147   0.154
184   K        -0.569  -0.563  -0.511  -0.861  -0.855  -0.769  -0.690  -0.681  -0.604
185   K        -0.569  -0.563  -0.511  -0.740  -0.737  -0.648  -0.690  -0.681  -0.604
186   Q         0.423   0.450   0.422   0.382   0.428   0.368   0.192   0.239   0.173
187   Q         1.789   1.793   1.841   1.811   1.817   1.898   1.955   1.962   2.032
188   K        -0.569  -0.563  -0.511  -0.717  -0.716  -0.625  -0.690  -0.681  -0.604
189   E        -0.569  -0.563  -0.511  -0.490  -0.483  -0.399  -0.690  -0.681  -0.604
190   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   R        -0.569  -0.563  -0.511  -0.632  -0.628  -0.541  -0.690  -0.681  -0.604
196   S         0.423   0.398   0.411   0.208   0.172   0.195   0.192   0.147   0.154
197   P         0.423   0.398   0.411   0.415   0.377   0.405   0.192   0.147   0.154
198   S        -0.569  -0.563  -0.511  -0.800  -0.789  -0.708  -0.690  -0.681  -0.604
199   R         0.423   0.398   0.411   0.326   0.279   0.292   0.192   0.147   0.154
200   V        -0.569  -0.563  -0.511  -0.516  -0.508  -0.425  -0.690  -0.681  -0.604
201   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   P         0.423   0.398   0.411   0.309   0.262   0.279   0.192   0.147   0.154
203   L         1.789   1.793   1.841   1.890   1.898   1.977   1.955   1.962   2.032
204   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   E         1.789   1.793   1.841   1.825   1.835   1.913   1.955   1.962   2.032
209   N        -0.569  -0.563  -0.511  -0.749  -0.733  -0.657  -0.690  -0.681  -0.604
210   F         0.423   0.398   0.411   0.408   0.358   0.367   0.192   0.147   0.154
211   E        -0.569  -0.563  -0.511  -0.533  -0.518  -0.441  -0.690  -0.681  -0.604
212   G         0.423   0.398   0.411   0.296   0.251   0.263   0.192   0.147   0.154
213   S        -1.070  -1.069  -1.061  -1.079  -1.076  -1.081  -0.901  -0.898  -0.868
214   S        -1.665  -1.659  -1.604  -1.420  -1.401  -1.328  -1.219  -1.211  -1.131
215   P        -0.250  -0.265  -0.341  -0.193  -0.216  -0.327  -0.266  -0.285  -0.381
216   Q        -1.070  -1.081  -1.065  -0.945  -0.965  -0.939  -0.901  -0.911  -0.872
217   P        -0.250  -0.239  -0.347  -0.261  -0.245  -0.424  -0.266  -0.251  -0.390
218   Q        -0.250  -0.238  -0.331  -0.120  -0.102  -0.240  -0.266  -0.251  -0.368
219   Y         1.789   1.793   1.841   1.748   1.754   1.836   1.955   1.962   2.032
220   D         0.344   0.351   0.387   0.174   0.185   0.238   0.051   0.061   0.109
221   A        -0.475  -0.445  -0.449  -0.629  -0.589  -0.583  -0.584  -0.550  -0.534
222   R         0.423   0.450   0.422   0.296   0.340   0.286   0.192   0.239   0.173
223   N         0.423   0.435   0.420   0.289   0.311   0.298   0.192   0.213   0.170
224   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   A        -0.569  -0.563  -0.511  -0.735  -0.724  -0.644  -0.690  -0.681  -0.604
238   H        -0.569  -0.563  -0.511  -0.571  -0.572  -0.480  -0.690  -0.681  -0.604
239   V        -0.569  -0.563  -0.511  -0.767  -0.763  -0.676  -0.690  -0.681  -0.604
240   A        -0.569  -0.563  -0.511  -0.511  -0.510  -0.420  -0.690  -0.681  -0.604
241   S         0.423   0.435   0.420   0.166   0.191   0.160   0.192   0.213   0.170
242   Q        -0.569  -0.563  -0.511  -0.545  -0.531  -0.454  -0.690  -0.681  -0.604
243   S         0.423   0.435   0.420   0.208   0.230   0.208   0.192   0.213   0.170
244   P         1.789   1.793   1.841   1.782   1.789   1.869   1.955   1.962   2.032
245   I        -0.569  -0.563  -0.511  -0.637  -0.629  -0.545  -0.690  -0.681  -0.604
246   F        -0.569  -0.563  -0.511  -0.567  -0.563  -0.476  -0.690  -0.681  -0.604
247   D         0.423   0.435   0.420   0.316   0.333   0.301   0.192   0.213   0.170
248   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   N        -1.186  -1.177  -1.126  -1.082  -1.048  -0.990  -1.020  -1.009  -0.934
255   Y        -0.442  -0.461  -0.448  -0.396  -0.433  -0.397  -0.524  -0.549  -0.524
256   Y        -0.442  -0.461  -0.448  -0.473  -0.509  -0.485  -0.524  -0.549  -0.524
257   Y        -0.442  -0.415  -0.443  -0.471  -0.425  -0.474  -0.524  -0.487  -0.517
258   D        -0.442  -0.410  -0.438  -0.452  -0.400  -0.455  -0.524  -0.480  -0.510
259   N        -0.442  -0.475  -0.457  -0.595  -0.645  -0.623  -0.524  -0.567  -0.536
260   N        -0.569  -0.555  -0.511  -0.760  -0.725  -0.669  -0.690  -0.671  -0.604
261   N        -0.442  -0.407  -0.457  -0.538  -0.487  -0.553  -0.524  -0.475  -0.536
262   I        -0.442  -0.433  -0.436  -0.624  -0.613  -0.611  -0.524  -0.511  -0.508
263   N         0.582   0.556   0.517   0.407   0.359   0.284   0.467   0.422   0.341
264   N        -0.442  -0.442  -0.442  -0.651  -0.660  -0.659  -0.524  -0.523  -0.516
265   N         0.582   0.612   0.487   0.458   0.501   0.301   0.467   0.516   0.290
266   L        -0.442  -0.407  -0.457  -0.378  -0.319  -0.407  -0.524  -0.475  -0.536
267   Q        -0.442  -0.434  -0.438  -0.437  -0.421  -0.433  -0.524  -0.512  -0.510
268   G        -0.442  -0.468  -0.440  -0.585  -0.634  -0.597  -0.524  -0.557  -0.514
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   N        -1.070  -1.052  -1.063  -1.032  -1.003  -1.030  -0.901  -0.880  -0.871
271   S        -1.070  -1.035  -1.052  -1.081  -1.024  -1.058  -0.901  -0.862  -0.859
272   Y        -0.250  -0.265  -0.341  -0.199  -0.223  -0.335  -0.266  -0.285  -0.381
273   N        -1.070  -1.070  -1.070  -1.120  -1.117  -1.122  -0.901  -0.899  -0.878
274   T        -1.665  -1.659  -1.604  -1.580  -1.574  -1.488  -1.219  -1.211  -1.131
275   P        -0.475  -0.475  -0.455  -0.552  -0.551  -0.509  -0.584  -0.582  -0.541
276   S         0.582   0.591   0.487   0.463   0.482   0.318   0.467   0.481   0.290
277   S         0.582   0.518   0.492   0.451   0.357   0.310   0.467   0.357   0.299
278   N        -0.442  -0.464  -0.448  -0.496  -0.531  -0.487  -0.524  -0.553  -0.524
279   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   R        -1.070  -1.097  -1.079  -0.983  -1.024  -1.006  -0.901  -0.927  -0.887
288   S        -1.070  -1.040  -1.059  -1.093  -1.043  -1.076  -0.901  -0.868  -0.867
289   P         0.715   0.702   0.557   0.730   0.711   0.493   0.686   0.665   0.412
290   Y         0.344   0.335   0.366   0.187   0.169   0.223   0.051   0.033   0.071
291   P        -0.442  -0.407  -0.457  -0.485  -0.425  -0.512  -0.524  -0.475  -0.536
292   T        -1.665  -1.659  -1.604  -1.369  -1.367  -1.276  -1.219  -1.211  -1.131
293   E        -0.250  -0.265  -0.341  -0.091  -0.113  -0.236  -0.266  -0.285  -0.381
294   N         0.344   0.342   0.370   0.121   0.118   0.162   0.051   0.045   0.077
295   Y        -1.070  -1.081  -1.065  -0.895  -0.913  -0.874  -0.901  -0.911  -0.872
296   Q        -1.665  -1.659  -1.604  -1.557  -1.553  -1.464  -1.219  -1.211  -1.131
297   S        -0.475  -0.479  -0.458  -0.652  -0.654  -0.612  -0.584  -0.586  -0.543
298   Y         0.715   0.702   0.557   0.745   0.727   0.513   0.686   0.665   0.412
299   Q        -1.665  -1.659  -1.604  -1.533  -1.531  -1.441  -1.219  -1.211  -1.131
300   G        -0.475  -0.479  -0.458  -0.478  -0.479  -0.440  -0.584  -0.586  -0.543
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   Y         0.715   0.679   0.571   0.754   0.702   0.548   0.686   0.628   0.436
304   K        -0.442  -0.452  -0.446  -0.412  -0.428  -0.420  -0.524  -0.538  -0.521
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   P         0.582   0.612   0.511   0.514   0.564   0.380   0.467   0.518   0.332
307   N        -0.442  -0.477  -0.457  -0.606  -0.665  -0.625  -0.524  -0.569  -0.536
308   Q        -0.569  -0.560  -0.511  -0.660  -0.639  -0.568  -0.690  -0.677  -0.604
309   S        -0.569  -0.560  -0.511  -0.796  -0.776  -0.704  -0.690  -0.677  -0.604
310   D        -0.569  -0.560  -0.511  -0.697  -0.676  -0.606  -0.690  -0.677  -0.604
311   R         1.789   1.793   1.841   1.855   1.867   1.943   1.955   1.962   2.032
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   Y         0.344   0.351   0.387   0.171   0.181   0.233   0.051   0.061   0.109
314   Y        -0.475  -0.478  -0.458  -0.637  -0.640  -0.596  -0.584  -0.584  -0.543
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12057
Output conservation file - output/Q12057
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
