1     M         1.888   1.980   2.048   2.101   2.248   2.361   2.097   2.234   2.361
2     T         1.080   0.957   0.963   1.141   0.958   0.979   1.034   0.776   0.747
3     K        -1.327  -1.269  -1.200  -1.236  -1.116  -1.049  -1.091  -1.015  -0.932
4     E         0.073   0.031   0.116  -0.163  -0.222  -0.101  -0.241  -0.290  -0.187
5     V         0.331   0.291   0.204   0.229   0.131  -0.025   0.184   0.096  -0.044
6     P         0.331   0.424   0.229   0.530   0.673   0.328   0.184   0.321  -0.005
7     Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    D        -0.502  -0.469  -0.426  -0.714  -0.673  -0.617  -0.658  -0.606  -0.557
11    N         1.888   1.980   2.048   1.886   2.020   2.141   2.097   2.234   2.361
12    D        -0.502  -0.493  -0.447  -0.545  -0.531  -0.463  -0.658  -0.635  -0.582
13    D         1.888   1.980   2.048   1.891   2.029   2.146   2.097   2.234   2.361
14    N        -0.502  -0.427  -0.443  -0.521  -0.383  -0.495  -0.658  -0.552  -0.577
15    N         0.990   1.052   0.927   0.951   1.039   0.807   0.873   0.957   0.674
16    I         0.073   0.031   0.116  -0.139  -0.170  -0.053  -0.241  -0.290  -0.187
17    I        -0.482  -0.382  -0.397  -0.681  -0.490  -0.535  -0.653  -0.540  -0.531
18    R         1.212   1.201   1.106   1.259   1.243   1.123   1.260   1.226   1.029
19    L        -0.054  -0.009   0.070  -0.487  -0.432  -0.307  -0.414  -0.353  -0.254
20    F         1.212   1.210   1.108   1.407   1.428   1.271   1.260   1.241   1.033
21    I         0.140   0.246   0.167  -0.185  -0.079  -0.161  -0.175  -0.056  -0.128
22    I         0.701   0.722   0.798   0.392   0.409   0.505   0.303   0.296   0.399
23    R         1.888   1.980   2.048   1.869   1.987   2.123   2.097   2.234   2.361
24    H         1.888   1.980   2.048   2.012   2.149   2.269   2.097   2.234   2.361
25    G         1.888   1.980   2.048   1.842   1.973   2.096   2.097   2.234   2.361
26    Q         1.212   1.097   1.092   1.363   1.209   1.200   1.260   1.039   1.003
27    T         1.888   1.980   2.048   1.875   2.010   2.129   2.097   2.234   2.361
28    E         0.140   0.105   0.191  -0.085  -0.094   0.005  -0.175  -0.189  -0.089
29    H        -0.038  -0.132  -0.240   0.220   0.077  -0.101  -0.055  -0.187  -0.320
30    N         1.888   1.980   2.048   1.922   2.095   2.178   2.097   2.234   2.361
31    V         0.273   0.337   0.219   0.133   0.184   0.012   0.064   0.115  -0.037
32    K        -0.482  -0.488  -0.423  -0.560  -0.568  -0.459  -0.653  -0.639  -0.558
33    K         0.701   0.709   0.792   0.422   0.393   0.519   0.303   0.268   0.386
34    I         1.212   1.097   1.092   1.217   1.079   1.039   1.260   1.039   1.003
35    L         0.568   0.388   0.336   0.548   0.296   0.233   0.543   0.263   0.166
36    Q         1.212   1.097   1.092   1.382   1.232   1.239   1.260   1.039   1.003
37    G         1.888   1.980   2.048   1.842   1.973   2.096   2.097   2.234   2.361
38    H        -0.038  -0.266  -0.288   0.225  -0.120  -0.175  -0.055  -0.348  -0.383
39    K        -1.221  -1.162  -1.147  -1.291  -1.238  -1.154  -1.012  -0.937  -0.890
40    D         1.888   1.980   2.048   1.881   2.035   2.135   2.097   2.234   2.361
41    T         0.273   0.156   0.201   0.192   0.017   0.052   0.064  -0.102  -0.066
42    S        -0.910  -0.833  -0.825  -0.880  -0.684  -0.730  -0.892  -0.792  -0.760
43    I         0.273   0.458   0.281   0.094   0.370   0.127   0.064   0.356   0.067
44    N         1.212   1.097   1.092   1.312   1.195   1.153   1.260   1.039   1.003
45    P        -1.104  -1.082  -1.100  -1.009  -0.984  -1.013  -0.892  -0.858  -0.846
46    T         0.568   0.388   0.336   0.680   0.436   0.348   0.543   0.263   0.166
47    G         1.888   1.980   2.048   1.842   1.973   2.096   2.097   2.234   2.361
48    E        -1.221  -1.060  -1.133  -1.214  -1.011  -1.076  -1.012  -0.856  -0.880
49    E        -0.910  -0.850  -0.821  -1.134  -1.058  -1.005  -0.892  -0.802  -0.758
50    Q         1.888   1.980   2.048   1.977   2.113   2.234   2.097   2.234   2.361
51    A         0.568   0.747   0.418   0.769   0.992   0.555   0.543   0.807   0.295
52    T        -1.532  -1.361  -1.432  -1.412  -1.163  -1.264  -1.131  -0.962  -0.991
53    K        -0.793  -0.853  -0.803  -0.935  -1.055  -0.984  -0.772  -0.814  -0.740
54    L         0.273   0.318   0.260   0.098   0.165   0.109   0.064   0.148   0.037
55    G         0.879   0.807   0.853   0.773   0.613   0.698   0.662   0.474   0.518
56    H        -0.793  -0.810  -0.766  -0.785  -0.802  -0.728  -0.772  -0.768  -0.703
57    Y        -0.599  -0.768  -0.756  -0.251  -0.519  -0.519  -0.533  -0.710  -0.685
58    L         0.568   0.388   0.336   0.538   0.276   0.212   0.543   0.263   0.166
59    R        -0.910  -0.871  -0.814  -1.011  -0.990  -0.869  -0.892  -0.831  -0.753
60    S        -1.221  -1.198  -1.145  -1.136  -1.057  -1.017  -1.012  -0.961  -0.889
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    R         1.888   1.980   2.048   1.817   1.928   2.071   2.097   2.234   2.361
85    G        -0.502  -0.430  -0.406  -0.573  -0.458  -0.440  -0.658  -0.567  -0.532
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   I        -0.482  -0.449  -0.419  -0.720  -0.683  -0.621  -0.653  -0.609  -0.556
111   H        -0.793  -0.666  -0.741  -0.598  -0.351  -0.499  -0.772  -0.610  -0.675
112   F         0.273   0.115   0.172   0.318   0.052   0.103   0.064  -0.172  -0.109
113   D        -0.038  -0.131  -0.235   0.075  -0.062  -0.240  -0.055  -0.185  -0.313
114   K        -1.532  -1.536  -1.463  -1.302  -1.285  -1.183  -1.131  -1.106  -1.014
115   V        -0.054   0.031   0.096  -0.326  -0.183  -0.103  -0.414  -0.296  -0.217
116   V        -0.482  -0.447  -0.418  -0.510  -0.441  -0.384  -0.653  -0.607  -0.556
117   S         0.273   0.236   0.211   0.277   0.214   0.187   0.064   0.010  -0.050
118   S         1.888   1.980   2.048   1.904   2.020   2.160   2.097   2.234   2.361
119   D         1.212   1.201   1.106   1.275   1.290   1.142   1.260   1.226   1.029
120   L         1.212   1.201   1.106   1.155   1.138   1.050   1.260   1.226   1.029
121   K        -0.288  -0.274  -0.306  -0.328  -0.268  -0.354  -0.414  -0.381  -0.418
122   R         1.888   1.980   2.048   1.869   1.987   2.123   2.097   2.234   2.361
123   C         1.212   1.097   1.092   1.552   1.407   1.408   1.260   1.039   1.003
124   R        -0.054  -0.035   0.059  -0.300  -0.319  -0.151  -0.414  -0.388  -0.269
125   Q        -0.288  -0.388  -0.362  -0.251  -0.435  -0.393  -0.414  -0.534  -0.489
126   T         1.888   1.980   2.048   1.875   2.010   2.129   2.097   2.234   2.361
127   T        -0.793  -0.794  -0.776  -0.864  -0.860  -0.849  -0.772  -0.758  -0.714
128   A        -1.532  -1.481  -1.441  -1.378  -1.271  -1.255  -1.131  -1.067  -0.998
129   L        -1.221  -1.125  -1.133  -1.100  -0.939  -0.985  -1.012  -0.908  -0.880
130   V        -1.104  -0.990  -1.094  -0.978  -0.798  -0.965  -0.892  -0.763  -0.840
131   L         1.212   1.097   1.092   1.114   0.925   0.950   1.260   1.039   1.003
132   K        -0.793  -0.796  -0.764  -0.822  -0.821  -0.772  -0.772  -0.752  -0.701
133   H        -0.599  -0.733  -0.745  -0.386  -0.634  -0.667  -0.533  -0.676  -0.673
134   S        -1.532  -1.435  -1.430  -1.182  -1.058  -1.025  -1.131  -1.027  -0.990
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   E        -1.221  -1.162  -1.147  -1.111  -1.007  -1.003  -1.012  -0.937  -0.890
148   N        -1.221  -1.205  -1.142  -1.166  -1.116  -1.042  -1.012  -0.973  -0.887
149   V        -0.910  -0.916  -0.818  -1.118  -1.152  -0.991  -0.892  -0.869  -0.757
150   P        -1.221  -1.176  -1.138  -1.079  -0.973  -0.959  -1.012  -0.951  -0.884
151   T        -0.793  -0.800  -0.785  -0.939  -0.999  -0.940  -0.772  -0.766  -0.723
152   S        -1.104  -0.928  -1.070  -0.990  -0.749  -0.940  -0.892  -0.695  -0.817
153   Y        -0.599  -0.612  -0.705  -0.251  -0.283  -0.430  -0.533  -0.548  -0.630
154   T         0.568   0.537   0.369   0.631   0.570   0.315   0.543   0.473   0.218
155   S        -1.221  -1.161  -1.141  -1.083  -0.997  -0.968  -1.012  -0.941  -0.887
156   G        -0.910  -0.875  -0.832  -1.132  -1.093  -1.023  -0.892  -0.834  -0.767
157   L         1.212   1.201   1.106   1.116   1.090   0.975   1.260   1.226   1.029
158   R         1.888   1.980   2.048   1.869   1.987   2.123   2.097   2.234   2.361
159   E         1.888   1.980   2.048   1.845   1.991   2.099   2.097   2.234   2.361
160   R         1.888   1.980   2.048   1.869   1.987   2.123   2.097   2.234   2.361
161   Y        -1.221  -1.136  -1.129  -0.999  -0.889  -0.857  -1.012  -0.916  -0.877
162   M         0.568   0.381   0.333   0.946   0.726   0.636   0.543   0.252   0.160
163   G         1.212   1.097   1.092   1.231   1.068   1.072   1.260   1.039   1.003
164   V        -1.532  -1.536  -1.463  -1.399  -1.422  -1.285  -1.131  -1.106  -1.014
165   I        -0.482  -0.529  -0.427  -0.758  -0.842  -0.683  -0.653  -0.681  -0.563
166   E         1.212   1.323   1.125   1.250   1.419   1.157   1.260   1.430   1.067
167   G         1.212   1.210   1.108   1.239   1.253   1.112   1.260   1.241   1.033
168   M         0.879   0.810   0.856   0.993   0.859   0.886   0.662   0.481   0.524
169   Q        -1.104  -1.142  -1.132  -0.714  -0.781  -0.768  -0.892  -0.914  -0.875
170   I        -0.793  -0.893  -0.802  -0.923  -1.045  -0.905  -0.772  -0.839  -0.737
171   T        -0.482  -0.512  -0.415  -0.696  -0.750  -0.608  -0.653  -0.663  -0.550
172   E         0.140   0.097   0.183  -0.085  -0.107  -0.003  -0.175  -0.201  -0.099
173   A         0.568   0.388   0.336   0.800   0.542   0.477   0.543   0.263   0.166
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   E        -0.182  -0.326  -0.340  -0.131  -0.357  -0.372  -0.245  -0.429  -0.449
176   K         0.459   0.465   0.293   0.484   0.487   0.210   0.379   0.373   0.098
177   Y        -0.038  -0.266  -0.288   0.323  -0.002  -0.057  -0.055  -0.348  -0.383
178   A        -0.793  -0.910  -0.819  -0.807  -1.055  -0.887  -0.772  -0.857  -0.754
179   D        -0.038   0.033  -0.195   0.123   0.255  -0.098  -0.055   0.044  -0.261
180   K        -0.498  -0.412  -0.409  -0.626  -0.493  -0.493  -0.666  -0.550  -0.539
181   H        -0.498  -0.448  -0.419  -0.470  -0.389  -0.346  -0.666  -0.595  -0.551
182   G         0.183   0.064   0.123   0.032  -0.221  -0.125  -0.046  -0.239  -0.172
183   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   S        -0.793  -0.559  -0.741  -0.712  -0.320  -0.626  -0.772  -0.489  -0.673
186   F        -0.038  -0.266  -0.288   0.315   0.014  -0.020  -0.055  -0.348  -0.383
187   R         0.273   0.115   0.172   0.187  -0.083  -0.005   0.064  -0.172  -0.109
188   N        -0.793  -0.896  -0.801  -0.694  -0.756  -0.672  -0.772  -0.842  -0.736
189   F        -0.599  -0.670  -0.721  -0.295  -0.409  -0.490  -0.533  -0.607  -0.648
190   G         1.212   1.097   1.092   1.248   1.093   1.104   1.260   1.039   1.003
191   E         1.212   1.097   1.092   1.234   1.087   1.075   1.260   1.039   1.003
192   K        -1.221  -1.198  -1.147  -1.131  -1.110  -1.007  -1.012  -0.967  -0.891
193   S        -1.532  -1.528  -1.463  -1.453  -1.494  -1.386  -1.131  -1.101  -1.014
194   D        -0.288  -0.312  -0.315  -0.350  -0.349  -0.399  -0.414  -0.413  -0.428
195   D        -1.221  -1.136  -1.146  -1.130  -0.966  -1.018  -1.012  -0.917  -0.890
196   F        -0.288  -0.424  -0.356  -0.235  -0.465  -0.371  -0.414  -0.560  -0.481
197   V        -1.221  -1.146  -1.133  -1.088  -1.004  -0.945  -1.012  -0.923  -0.880
198   A        -1.532  -1.452  -1.431  -1.374  -1.264  -1.232  -1.131  -1.040  -0.991
199   R         1.212   1.097   1.092   1.279   1.120   1.139   1.260   1.039   1.003
200   L         0.879   1.014   0.968   0.615   0.794   0.734   0.662   0.886   0.757
201   T        -0.910  -0.859  -0.811  -1.073  -1.007  -0.932  -0.892  -0.819  -0.749
202   G        -0.793  -0.731  -0.759  -0.779  -0.624  -0.698  -0.772  -0.684  -0.692
203   C        -1.532  -1.504  -1.465  -1.389  -1.393  -1.278  -1.131  -1.085  -1.015
204   V        -0.288  -0.137  -0.313  -0.148   0.036  -0.242  -0.414  -0.247  -0.430
205   E        -0.288  -0.022  -0.256  -0.323   0.121  -0.253  -0.414  -0.048  -0.348
206   E        -1.104  -1.091  -1.099  -1.058  -1.050  -1.072  -0.892  -0.866  -0.845
207   E        -0.038   0.110  -0.183   0.134   0.378  -0.045  -0.055   0.143  -0.245
208   V         0.568   0.527   0.380   0.623   0.548   0.350   0.543   0.459   0.235
209   A        -1.221  -1.217  -1.146  -1.216  -1.209  -1.098  -1.012  -0.982  -0.890
210   E        -1.248  -1.270  -1.181  -1.289  -1.329  -1.201  -1.026  -1.019  -0.917
211   A        -0.502  -0.535  -0.447  -0.649  -0.753  -0.607  -0.658  -0.685  -0.582
212   S        -0.498  -0.492  -0.419  -0.754  -0.760  -0.640  -0.666  -0.640  -0.551
213   N        -1.248  -1.270  -1.181  -1.095  -1.066  -0.995  -1.026  -1.019  -0.917
214   E        -0.793  -0.703  -0.748  -0.840  -0.693  -0.773  -0.772  -0.663  -0.687
215   G        -1.221  -1.199  -1.154  -1.253  -1.217  -1.148  -1.012  -0.967  -0.896
216   V        -1.532  -1.504  -1.465  -1.298  -1.228  -1.233  -1.131  -1.085  -1.015
217   K        -1.104  -1.102  -1.110  -0.999  -1.023  -1.027  -0.892  -0.875  -0.855
218   N        -0.038  -0.266  -0.288   0.176  -0.122  -0.184  -0.055  -0.348  -0.383
219   L        -0.599  -0.305  -0.638  -0.474  -0.051  -0.527  -0.533  -0.168  -0.555
220   A        -0.910  -0.948  -0.827  -1.104  -1.206  -0.998  -0.892  -0.893  -0.763
221   L        -0.365  -0.168  -0.333  -0.529  -0.243  -0.457  -0.533  -0.299  -0.458
222   V         0.273   0.311   0.262   0.240   0.283   0.219   0.064   0.138   0.040
223   S        -0.365  -0.455  -0.372  -0.390  -0.497  -0.342  -0.533  -0.601  -0.501
224   H         1.888   1.980   2.048   2.012   2.149   2.269   2.097   2.234   2.361
225   G         1.888   1.980   2.048   1.842   1.973   2.096   2.097   2.234   2.361
226   G         1.212   1.097   1.092   1.211   1.034   1.032   1.260   1.039   1.003
227   A        -0.793  -0.791  -0.782  -0.762  -0.762  -0.712  -0.772  -0.746  -0.717
228   I         1.212   1.097   1.092   1.217   1.079   1.039   1.260   1.039   1.003
229   R        -0.054  -0.029   0.062  -0.331  -0.283  -0.159  -0.414  -0.379  -0.265
230   M        -1.221  -1.195  -1.145  -1.078  -1.113  -0.954  -1.012  -0.967  -0.889
231   I        -0.054   0.054   0.102  -0.357  -0.215  -0.138  -0.414  -0.269  -0.210
232   L        -0.365  -0.407  -0.354  -0.633  -0.694  -0.608  -0.533  -0.552  -0.483
233   Q        -0.793  -0.708  -0.771  -0.781  -0.663  -0.754  -0.772  -0.681  -0.711
234   W        -0.793  -0.800  -0.784  -0.510  -0.524  -0.513  -0.772  -0.754  -0.718
235   L         1.212   1.201   1.106   1.142   1.117   1.025   1.260   1.226   1.029
236   -        -1.000  -0.957  -0.870  -0.976  -0.946  -0.783  -0.964  -0.900  -0.800
237   -        -1.000  -0.957  -0.870  -1.074  -0.999  -0.883  -0.964  -0.900  -0.800
238   -        -0.502  -0.436  -0.410  -0.684  -0.575  -0.559  -0.658  -0.569  -0.538
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -0.005   0.096   0.111  -0.350  -0.182  -0.192  -0.352  -0.220  -0.199
243   K        -0.910  -0.859  -0.814  -1.007  -0.898  -0.850  -0.892  -0.822  -0.753
244   Y         0.273   0.115   0.172   0.485   0.273   0.335   0.064  -0.172  -0.109
245   E        -1.221  -1.099  -1.140  -1.210  -0.995  -1.085  -1.012  -0.877  -0.885
246   N        -1.104  -1.049  -1.113  -1.091  -1.054  -1.095  -0.892  -0.829  -0.857
247   H        -1.221  -1.113  -1.133  -1.233  -1.128  -1.092  -1.012  -0.899  -0.880
248   Q        -1.104  -1.171  -1.131  -0.967  -1.077  -1.036  -0.892  -0.938  -0.873
249   A        -1.221  -1.199  -1.154  -1.206  -1.210  -1.132  -1.012  -0.967  -0.896
250   H        -0.893  -0.914  -0.842  -0.931  -0.986  -0.843  -0.870  -0.867  -0.775
251   K         0.568   0.631   0.401   0.669   0.773   0.433   0.543   0.629   0.268
252   -        -0.005   0.056   0.106  -0.276  -0.226  -0.148  -0.352  -0.264  -0.203
253   -        -0.005  -0.003   0.106  -0.259  -0.267  -0.096  -0.352  -0.345  -0.206
254   -         0.183   0.361   0.228   0.135   0.403   0.187  -0.046   0.225  -0.006
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -         0.990   1.042   1.000   0.755   0.819   0.755   0.873   0.938   0.821
265   I        -0.288  -0.386  -0.338  -0.348  -0.453  -0.416  -0.414  -0.507  -0.452
266   I        -0.288  -0.386  -0.338  -0.359  -0.472  -0.425  -0.414  -0.507  -0.452
267   V        -0.365  -0.455  -0.372  -0.299  -0.349  -0.249  -0.533  -0.601  -0.501
268   F        -0.038  -0.131  -0.235   0.277   0.126  -0.001  -0.055  -0.185  -0.313
269   N         1.888   1.980   2.048   1.922   2.095   2.178   2.097   2.234   2.361
270   T         1.888   1.980   2.048   1.875   2.010   2.129   2.097   2.234   2.361
271   S         1.212   1.097   1.092   1.290   1.112   1.126   1.260   1.039   1.003
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   V        -0.038  -0.266  -0.288   0.077  -0.257  -0.288  -0.055  -0.348  -0.383
282   T         0.701   0.740   0.811   0.453   0.479   0.600   0.303   0.336   0.428
283   I        -0.365  -0.455  -0.372  -0.552  -0.660  -0.549  -0.533  -0.601  -0.501
284   V        -0.288  -0.352  -0.321  -0.364  -0.404  -0.402  -0.414  -0.461  -0.430
285   D         0.879   0.807   0.853   0.765   0.622   0.658   0.662   0.474   0.518
286   Y        -0.482  -0.540  -0.425  -0.542  -0.639  -0.500  -0.653  -0.693  -0.562
287   V        -1.221  -1.181  -1.144  -1.292  -1.180  -1.178  -1.012  -0.949  -0.888
288   K         0.568   0.480   0.351   0.658   0.554   0.331   0.543   0.408   0.189
289   D        -0.793  -0.837  -0.772  -0.730  -0.747  -0.674  -0.772  -0.787  -0.705
290   S        -1.104  -0.920  -1.065  -1.049  -0.758  -1.012  -0.892  -0.688  -0.813
291   K        -0.182  -0.348  -0.340  -0.081  -0.327  -0.331  -0.245  -0.461  -0.449
292   Q        -0.288  -0.192  -0.285  -0.234  -0.091  -0.217  -0.414  -0.275  -0.386
293   F        -0.288  -0.221  -0.307  -0.282  -0.225  -0.306  -0.414  -0.314  -0.415
294   I        -0.482  -0.477  -0.415  -0.674  -0.633  -0.566  -0.653  -0.627  -0.552
295   V         0.140   0.140   0.166  -0.143  -0.139  -0.111  -0.175  -0.163  -0.127
296   R        -0.365  -0.455  -0.372  -0.410  -0.534  -0.390  -0.533  -0.601  -0.501
297   R        -0.599  -0.598  -0.715  -0.499  -0.525  -0.700  -0.533  -0.518  -0.641
298   V         0.644   0.709   0.793   0.398   0.489   0.627   0.184   0.269   0.387
299   G         0.568   0.388   0.336   0.655   0.407   0.332   0.543   0.263   0.166
300   N         0.273   0.115   0.172   0.236   0.003   0.037   0.064  -0.172  -0.109
301   T        -0.038  -0.266  -0.288   0.057  -0.317  -0.359  -0.055  -0.348  -0.383
302   Q        -0.793  -0.819  -0.794  -0.759  -0.820  -0.788  -0.772  -0.782  -0.732
303   H         1.888   1.980   2.048   2.012   2.149   2.269   2.097   2.234   2.361
304   L         1.888   1.980   2.048   1.731   1.836   1.982   2.097   2.234   2.361
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   G         0.568   0.480   0.351   0.625   0.509   0.299   0.543   0.408   0.189
316   D         0.073   0.147   0.175  -0.152  -0.016   0.009  -0.241  -0.116  -0.095
317   G        -0.288  -0.399  -0.357  -0.344  -0.538  -0.457  -0.414  -0.541  -0.485
318   E        -0.038  -0.052  -0.211   0.070   0.057  -0.185  -0.055  -0.081  -0.283
319   F         0.459   0.437   0.303   0.633   0.606   0.360   0.379   0.337   0.112
320   V        -0.893  -0.908  -0.842  -1.060  -1.061  -0.996  -0.870  -0.863  -0.775
321   V         1.152   1.018   1.035   1.147   0.929   0.974   1.160   0.893   0.891
322   S         0.140   0.123   0.167  -0.037  -0.072   0.008  -0.175  -0.191  -0.128
323   D        -0.599  -0.768  -0.756  -0.477  -0.711  -0.743  -0.533  -0.710  -0.685
324   L        -0.482  -0.484  -0.422  -0.666  -0.640  -0.536  -0.653  -0.635  -0.558
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   R        -0.365  -0.309  -0.349  -0.597  -0.565  -0.552  -0.533  -0.461  -0.478
339   L        -0.038  -0.266  -0.288  -0.090  -0.473  -0.500  -0.055  -0.348  -0.383
340   R        -0.038  -0.266  -0.288   0.148  -0.186  -0.189  -0.055  -0.348  -0.383
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12040
Output conservation file - output/Q12040
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
