1     M         1.739   1.796   1.820   2.046   2.140   2.187   1.919   1.997   2.036
2     F        -0.583  -0.611  -0.604  -0.707  -0.811  -0.726  -0.637  -0.660  -0.642
3     R         0.483   0.365   0.374   0.569   0.318   0.350   0.385   0.180   0.185
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    Q        -1.357  -1.318  -1.297  -0.851  -0.786  -0.745  -1.148  -1.079  -1.044
12    S         1.739   1.796   1.820   1.766   1.874   1.905   1.919   1.997   2.036
13    I        -1.357  -1.318  -1.297  -1.018  -0.906  -0.915  -1.148  -1.079  -1.044
14    R         0.317   0.279   0.305   0.259   0.160   0.203   0.101   0.027   0.063
15    P         0.317   0.392   0.350   0.127   0.209   0.193   0.101   0.226   0.143
16    L        -0.583  -0.611  -0.604  -0.492  -0.528  -0.545  -0.637  -0.660  -0.642
17    V        -1.357  -1.318  -1.297  -1.413  -1.335  -1.314  -1.148  -1.079  -1.044
18    S        -0.583  -0.489  -0.561  -0.559  -0.383  -0.534  -0.637  -0.493  -0.586
19    N        -1.357  -1.318  -1.297  -0.998  -0.936  -0.894  -1.148  -1.079  -1.044
20    R         1.739   1.796   1.820   1.896   1.980   2.036   1.919   1.997   2.036
21    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    T        -0.583  -0.622  -0.608  -0.357  -0.407  -0.388  -0.637  -0.673  -0.647
23    F        -0.583  -0.622  -0.608  -0.387  -0.438  -0.454  -0.637  -0.673  -0.647
24    I        -0.583  -0.611  -0.604  -0.377  -0.373  -0.383  -0.637  -0.660  -0.642
25    R         1.739   1.796   1.820   1.896   1.980   2.036   1.919   1.997   2.036
26    Y         0.191   0.231   0.267   0.372   0.455   0.501  -0.126  -0.060  -0.007
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    N        -0.583  -0.598  -0.600  -0.479  -0.513  -0.541  -0.637  -0.646  -0.637
52    S         0.483   0.365   0.374   0.442   0.217   0.228   0.385   0.180   0.185
53    S        -0.583  -0.622  -0.608  -0.627  -0.734  -0.675  -0.637  -0.673  -0.647
54    P         0.317   0.407   0.354   0.533   0.692   0.595   0.101   0.252   0.150
55    A        -0.583  -0.474  -0.556  -0.652  -0.527  -0.595  -0.637  -0.473  -0.580
56    Y         0.483   0.365   0.374   0.855   0.693   0.698   0.385   0.180   0.185
57    T        -1.357  -1.318  -1.297  -1.219  -1.198  -1.118  -1.148  -1.079  -1.044
58    A        -1.357  -1.318  -1.297  -1.162  -1.055  -1.060  -1.148  -1.079  -1.044
59    A        -1.357  -1.318  -1.297  -1.380  -1.388  -1.280  -1.148  -1.079  -1.044
60    V        -0.583  -0.611  -0.604  -0.444  -0.435  -0.457  -0.637  -0.660  -0.642
61    S        -0.583  -0.489  -0.561  -0.666  -0.563  -0.617  -0.637  -0.493  -0.586
62    L        -1.357  -1.318  -1.297  -1.656  -1.625  -1.560  -1.148  -1.079  -1.044
63    L         1.739   1.796   1.820   1.617   1.702   1.753   1.919   1.997   2.036
64    K         1.739   1.796   1.820   1.446   1.558   1.580   1.919   1.997   2.036
65    G        -0.583  -0.474  -0.556  -0.472  -0.276  -0.438  -0.637  -0.473  -0.580
66    D         1.739   1.796   1.820   1.775   1.867   1.913   1.919   1.997   2.036
67    L         1.739   1.796   1.820   1.617   1.702   1.753   1.919   1.997   2.036
68    K         1.739   1.796   1.820   1.446   1.558   1.580   1.919   1.997   2.036
69    K        -0.583  -0.622  -0.608  -0.858  -0.887  -0.869  -0.637  -0.673  -0.647
70    A         1.739   1.796   1.820   1.592   1.635   1.728   1.919   1.997   2.036
71    M         1.739   1.796   1.820   2.046   2.140   2.187   1.919   1.997   2.036
72    I        -1.357  -1.318  -1.297  -1.356  -1.235  -1.256  -1.148  -1.079  -1.044
73    A         0.483   0.565   0.428   0.380   0.465   0.310   0.385   0.518   0.280
74    K         1.739   1.796   1.820   1.446   1.558   1.580   1.919   1.997   2.036
75    D         1.739   1.796   1.820   1.775   1.867   1.913   1.919   1.997   2.036
76    E        -0.583  -0.459  -0.556  -0.645  -0.494  -0.587  -0.637  -0.453  -0.580
77    M        -0.583  -0.611  -0.604  -0.499  -0.511  -0.479  -0.637  -0.660  -0.642
78    K         0.191   0.231   0.267  -0.154  -0.049  -0.005  -0.126  -0.060  -0.007
79    K         0.483   0.365   0.374   0.132  -0.055  -0.066   0.385   0.180   0.185
80    T         0.483   0.365   0.374   0.665   0.468   0.481   0.385   0.180   0.185
81    A        -0.583  -0.598  -0.600  -0.677  -0.745  -0.680  -0.637  -0.646  -0.637
82    I         0.483   0.365   0.374   0.482   0.291   0.271   0.385   0.180   0.185
83    R         0.483   0.565   0.428   0.525   0.667   0.400   0.385   0.518   0.280
84    N        -1.357  -1.318  -1.297  -1.193  -1.199  -1.091  -1.148  -1.079  -1.044
85    M        -0.583  -0.489  -0.561  -0.434  -0.290  -0.387  -0.637  -0.493  -0.586
86    L         1.739   1.796   1.820   1.617   1.702   1.753   1.919   1.997   2.036
87    S         0.483   0.365   0.374   0.442   0.217   0.228   0.385   0.180   0.185
88    A         0.191   0.234   0.269  -0.031  -0.012   0.080  -0.126  -0.054  -0.002
89    I         0.483   0.365   0.374   0.548   0.375   0.370   0.385   0.180   0.185
90    K         0.483   0.365   0.374   0.132  -0.055  -0.066   0.385   0.180   0.185
91    N         1.739   1.796   1.820   2.007   2.119   2.148   1.919   1.997   2.036
92    K        -0.583  -0.622  -0.608  -0.870  -0.949  -0.883  -0.637  -0.673  -0.647
93    E         0.483   0.365   0.374   0.538   0.351   0.350   0.385   0.180   0.185
94    I         0.483   0.365   0.374   0.429   0.228   0.190   0.385   0.180   0.185
95    A        -0.583  -0.611  -0.604  -0.619  -0.653  -0.661  -0.637  -0.660  -0.642
96    L        -0.583  -0.459  -0.556  -0.843  -0.669  -0.802  -0.637  -0.453  -0.580
97    K         0.483   0.365   0.374   0.247   0.106   0.105   0.385   0.180   0.185
98    G        -0.583  -0.611  -0.604  -0.390  -0.412  -0.387  -0.637  -0.660  -0.642
99    K         0.483   0.365   0.374   0.195   0.050   0.029   0.385   0.180   0.185
100   S        -0.583  -0.598  -0.600  -0.598  -0.606  -0.627  -0.637  -0.646  -0.637
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   A        -0.583  -0.611  -0.604  -0.759  -0.788  -0.789  -0.637  -0.660  -0.642
103   D         1.739   1.796   1.820   1.775   1.867   1.913   1.919   1.997   2.036
104   E         0.483   0.365   0.374   0.482   0.246   0.266   0.385   0.180   0.185
105   Y         0.317   0.368   0.313   0.566   0.658   0.561   0.101   0.184   0.077
106   S        -0.583  -0.598  -0.600  -0.517  -0.519  -0.530  -0.637  -0.646  -0.637
107   L         1.739   1.796   1.820   1.617   1.702   1.753   1.919   1.997   2.036
108   Y        -0.583  -0.622  -0.608  -0.182  -0.264  -0.209  -0.637  -0.673  -0.647
109   D         0.483   0.365   0.374   0.450   0.211   0.235   0.385   0.180   0.185
110   M        -1.357  -1.318  -1.297  -1.351  -1.353  -1.252  -1.148  -1.079  -1.044
111   Y        -0.583  -0.622  -0.608  -0.327  -0.427  -0.385  -0.637  -0.673  -0.647
112   S        -1.357  -1.318  -1.297  -1.300  -1.213  -1.200  -1.148  -1.079  -1.044
113   K         1.739   1.796   1.820   1.446   1.558   1.580   1.919   1.997   2.036
114   L        -0.583  -0.622  -0.608  -0.555  -0.593  -0.549  -0.637  -0.673  -0.647
115   I        -0.583  -0.622  -0.608  -0.641  -0.751  -0.702  -0.637  -0.673  -0.647
116   S        -0.583  -0.622  -0.608  -0.637  -0.693  -0.688  -0.637  -0.673  -0.647
117   Q         0.483   0.365   0.374   0.616   0.372   0.395   0.385   0.180   0.185
118   R         0.483   0.365   0.374   0.624   0.422   0.432   0.385   0.180   0.185
119   K        -0.583  -0.622  -0.608  -0.707  -0.702  -0.687  -0.637  -0.673  -0.647
120   D         0.483   0.365   0.374   0.519   0.331   0.339   0.385   0.180   0.185
121   S         0.483   0.365   0.374   0.442   0.217   0.228   0.385   0.180   0.185
122   I         0.483   0.365   0.374   0.474   0.261   0.259   0.385   0.180   0.185
123   N        -1.357  -1.318  -1.297  -1.501  -1.411  -1.403  -1.148  -1.079  -1.044
124   E         0.483   0.365   0.374   0.595   0.424   0.435   0.385   0.180   0.185
125   F         1.739   1.796   1.820   2.030   2.132   2.172   1.919   1.997   2.036
126   L        -1.357  -1.318  -1.297  -1.323  -1.228  -1.223  -1.148  -1.079  -1.044
127   A         0.483   0.607   0.441   0.221   0.391   0.126   0.385   0.586   0.303
128   N         0.483   0.365   0.374   0.677   0.449   0.454   0.385   0.180   0.185
129   K         0.483   0.365   0.374   0.266   0.125   0.134   0.385   0.180   0.185
130   R         1.739   1.796   1.820   1.896   1.980   2.036   1.919   1.997   2.036
131   D        -0.583  -0.598  -0.600  -0.492  -0.498  -0.503  -0.637  -0.646  -0.637
132   D         1.739   1.796   1.820   1.775   1.867   1.913   1.919   1.997   2.036
133   L         1.739   1.796   1.820   1.617   1.702   1.753   1.919   1.997   2.036
134   V         0.483   0.565   0.428   0.498   0.604   0.390   0.385   0.518   0.280
135   A         0.483   0.586   0.432   0.482   0.648   0.381   0.385   0.552   0.287
136   K         1.739   1.796   1.820   1.446   1.558   1.580   1.919   1.997   2.036
137   E         0.483   0.565   0.428   0.540   0.681   0.451   0.385   0.518   0.280
138   Q        -1.357  -1.318  -1.297  -1.521  -1.428  -1.424  -1.148  -1.079  -1.044
139   G        -1.357  -1.318  -1.297  -1.098  -1.118  -0.995  -1.148  -1.079  -1.044
140   E         0.483   0.365   0.374   0.595   0.424   0.435   0.385   0.180   0.185
141   M         0.483   0.586   0.432   0.621   0.806   0.565   0.385   0.552   0.287
142   D        -1.357  -1.318  -1.297  -1.442  -1.313  -1.343  -1.148  -1.079  -1.044
143   I         0.191   0.238   0.271   0.047   0.133   0.185  -0.126  -0.047   0.001
144   I         0.191   0.231   0.267  -0.104  -0.032   0.012  -0.126  -0.060  -0.007
145   K        -0.583  -0.489  -0.561  -0.612  -0.418  -0.581  -0.637  -0.493  -0.586
146   K        -0.583  -0.598  -0.600  -0.770  -0.760  -0.756  -0.637  -0.646  -0.637
147   Y         1.739   1.796   1.820   2.046   2.152   2.187   1.919   1.997   2.036
148   M        -1.357  -1.318  -1.297  -1.158  -1.114  -1.056  -1.148  -1.079  -1.044
149   D        -1.357  -1.318  -1.297  -1.557  -1.528  -1.460  -1.148  -1.079  -1.044
150   Q        -1.357  -1.318  -1.297  -1.206  -1.124  -1.104  -1.148  -1.079  -1.044
151   L         0.483   0.365   0.374   0.352   0.163   0.173   0.385   0.180   0.185
152   P         0.483   0.365   0.374   0.840   0.655   0.676   0.385   0.180   0.185
153   V         1.739   1.796   1.820   1.823   1.894   1.962   1.919   1.997   2.036
154   S        -0.583  -0.598  -0.600  -0.616  -0.616  -0.648  -0.637  -0.646  -0.637
155   S         1.739   1.796   1.820   1.766   1.874   1.905   1.919   1.997   2.036
156   E        -1.357  -1.318  -1.297  -1.333  -1.293  -1.233  -1.148  -1.079  -1.044
157   L        -0.583  -0.611  -0.604  -0.645  -0.688  -0.700  -0.637  -0.660  -0.642
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   D         0.191   0.231   0.267   0.017   0.093   0.146  -0.126  -0.060  -0.007
161   I        -0.583  -0.459  -0.556  -0.711  -0.512  -0.661  -0.637  -0.453  -0.580
162   D         0.191   0.238   0.271  -0.249  -0.176  -0.139  -0.126  -0.047   0.001
163   Q        -1.357  -1.318  -1.297  -1.269  -1.213  -1.168  -1.148  -1.079  -1.044
164   N        -1.357  -1.318  -1.297  -1.171  -1.047  -1.069  -1.148  -1.079  -1.044
165   V         0.483   0.565   0.428   0.498   0.604   0.390   0.385   0.518   0.280
166   K        -1.357  -1.318  -1.297  -1.319  -1.202  -1.219  -1.148  -1.079  -1.044
167   K        -1.357  -1.318  -1.297  -1.521  -1.493  -1.424  -1.148  -1.079  -1.044
168   L        -1.357  -1.318  -1.297  -1.237  -1.156  -1.136  -1.148  -1.079  -1.044
169   L         0.483   0.365   0.374   0.412   0.239   0.262   0.385   0.180   0.185
170   D        -1.357  -1.318  -1.297  -1.452  -1.346  -1.353  -1.148  -1.079  -1.044
171   A        -1.357  -1.318  -1.297  -1.333  -1.267  -1.233  -1.148  -1.079  -1.044
172   L         1.739   1.796   1.820   1.617   1.702   1.753   1.919   1.997   2.036
173   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   K        -0.583  -0.622  -0.608  -0.902  -0.988  -0.921  -0.637  -0.673  -0.647
176   A         0.191   0.234   0.269  -0.117  -0.093   0.001  -0.126  -0.054  -0.002
177   G        -0.583  -0.611  -0.604  -0.513  -0.562  -0.532  -0.637  -0.660  -0.642
178   E         0.483   0.365   0.374   0.613   0.441   0.462   0.385   0.180   0.185
179   K        -0.583  -0.611  -0.604  -0.482  -0.533  -0.565  -0.637  -0.660  -0.642
180   K        -1.357  -1.318  -1.297  -1.399  -1.283  -1.300  -1.148  -1.079  -1.044
181   V        -1.357  -1.318  -1.297  -1.501  -1.489  -1.403  -1.148  -1.079  -1.044
182   Q         0.483   0.365   0.374   0.572   0.340   0.328   0.385   0.180   0.185
183   I        -0.583  -0.611  -0.604  -0.609  -0.600  -0.609  -0.637  -0.660  -0.642
184   K         0.483   0.365   0.374   0.266   0.125   0.134   0.385   0.180   0.185
185   E        -0.583  -0.611  -0.604  -0.444  -0.501  -0.493  -0.637  -0.660  -0.642
186   I        -0.583  -0.489  -0.561  -0.619  -0.457  -0.590  -0.637  -0.493  -0.586
187   M         0.191   0.234   0.269   0.372   0.454   0.508  -0.126  -0.054  -0.002
188   G         0.483   0.365   0.374   0.626   0.376   0.381   0.385   0.180   0.185
189   E         0.483   0.586   0.432   0.198   0.382   0.125   0.385   0.552   0.287
190   I        -0.583  -0.622  -0.608  -0.630  -0.712  -0.688  -0.637  -0.673  -0.647
191   D         0.483   0.365   0.374   0.458   0.241   0.247   0.385   0.180   0.185
192   W         0.483   0.365   0.374   0.942   0.760   0.773   0.385   0.180   0.185
193   K        -0.583  -0.622  -0.608  -0.767  -0.747  -0.758  -0.637  -0.673  -0.647
194   S        -1.357  -1.318  -1.297  -1.241  -1.157  -1.140  -1.148  -1.079  -1.044
195   L         0.483   0.365   0.374   0.431   0.257   0.290   0.385   0.180   0.185
196   P        -0.583  -0.622  -0.608  -0.262  -0.332  -0.305  -0.637  -0.673  -0.647
197   T        -1.357  -1.318  -1.297  -1.403  -1.364  -1.304  -1.148  -1.079  -1.044
198   E         0.191   0.238   0.271   0.017   0.101   0.151  -0.126  -0.047   0.001
199   W        -0.583  -0.598  -0.600  -0.249  -0.264  -0.300  -0.637  -0.646  -0.637
200   K         1.739   1.796   1.820   1.446   1.558   1.580   1.919   1.997   2.036
201   T        -0.583  -0.611  -0.604  -0.699  -0.776  -0.711  -0.637  -0.660  -0.642
202   S         0.483   0.365   0.374   0.517   0.332   0.340   0.385   0.180   0.185
203   P        -0.583  -0.622  -0.608  -0.288  -0.366  -0.337  -0.637  -0.673  -0.647
204   T        -0.583  -0.459  -0.556  -0.913  -0.706  -0.864  -0.637  -0.453  -0.580
205   A        -0.583  -0.622  -0.608  -0.703  -0.759  -0.721  -0.637  -0.673  -0.647
206   I         0.483   0.365   0.374   0.482   0.291   0.271   0.385   0.180   0.185
207   K        -0.583  -0.611  -0.604  -0.616  -0.665  -0.689  -0.637  -0.660  -0.642
208   N        -1.357  -1.318  -1.297  -1.237  -1.222  -1.136  -1.148  -1.079  -1.044
209   S        -0.583  -0.622  -0.608  -0.496  -0.535  -0.516  -0.637  -0.673  -0.647
210   I         1.739   1.796   1.820   1.799   1.920   1.938   1.919   1.997   2.036
211   V         0.483   0.607   0.441   0.553   0.737   0.486   0.385   0.586   0.303
212   K         0.191   0.234   0.269  -0.256  -0.176  -0.146  -0.126  -0.054  -0.002
213   Q         0.191   0.238   0.271   0.141   0.216   0.269  -0.126  -0.047   0.001
214   F         0.483   0.365   0.374   0.771   0.571   0.581   0.385   0.180   0.185
215   K         0.483   0.365   0.374   0.283   0.156   0.159   0.385   0.180   0.185
216   E        -1.357  -1.318  -1.297  -1.246  -1.114  -1.145  -1.148  -1.079  -1.044
217   I        -0.583  -0.598  -0.600  -0.499  -0.492  -0.517  -0.637  -0.646  -0.637
218   F         0.483   0.365   0.374   0.657   0.430   0.411   0.385   0.180   0.185
219   K        -0.583  -0.598  -0.600  -0.902  -0.961  -0.911  -0.637  -0.646  -0.637
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12032
Output conservation file - output/Q12032
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
