1     M         1.053   1.082   1.139   1.231   1.269   1.346   1.110   1.148   1.230
2     A        -0.322  -0.580  -0.673  -0.326  -0.696  -0.866  -0.315  -0.655  -0.783
3     S        -0.322  -0.580  -0.673  -0.224  -0.561  -0.711  -0.315  -0.655  -0.783
4     S         0.349   0.175   0.061   0.366   0.140  -0.044   0.343   0.074  -0.149
5     V        -1.294  -1.400  -1.216  -1.459  -1.617  -1.344  -1.301  -1.361  -1.123
6     P        -0.953  -0.930  -1.161  -0.744  -0.727  -1.102  -0.863  -0.845  -1.062
7     G         1.053   1.082   1.139   1.063   1.107   1.196   1.110   1.148   1.230
8     P        -0.953  -1.185  -1.198  -0.717  -1.057  -1.110  -0.863  -1.121  -1.101
9     I        -0.970  -0.924  -0.748  -1.199  -1.134  -0.849  -1.191  -1.117  -0.880
10    D        -1.862  -1.797  -1.617  -1.901  -1.809  -1.495  -1.630  -1.542  -1.300
11    L         0.349   0.175   0.061   0.152  -0.097  -0.272   0.343   0.074  -0.149
12    P         1.053   1.082   1.139   1.099   1.140   1.228   1.110   1.148   1.230
13    E        -0.733  -0.728  -0.725  -0.566  -0.586  -0.554  -0.894  -0.909  -0.854
14    S         0.349   0.175   0.061   0.396   0.189   0.038   0.343   0.074  -0.149
15    R        -1.740  -1.823  -1.624  -1.630  -1.775  -1.507  -1.520  -1.553  -1.304
16    Y        -0.322  -0.368  -0.641   0.097   0.008  -0.406  -0.315  -0.394  -0.740
17    D         0.349   0.175   0.061   0.585   0.319   0.061   0.343   0.074  -0.149
18    L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
19    S        -1.538  -1.504  -1.577  -1.344  -1.297  -1.380  -1.301  -1.263  -1.265
20    T        -0.322  -0.414  -0.647  -0.237  -0.381  -0.779  -0.315  -0.448  -0.748
21    Y         0.349   0.175   0.061   0.697   0.466   0.255   0.343   0.074  -0.149
22    W         0.349   0.175   0.061   0.724   0.496   0.286   0.343   0.074  -0.149
23    G         0.349   0.175   0.061   0.406   0.149  -0.091   0.343   0.074  -0.149
24    R         0.349   0.175   0.061   0.560   0.337   0.152   0.343   0.074  -0.149
25    I        -0.322  -0.360  -0.639  -0.286  -0.350  -0.708  -0.315  -0.385  -0.738
26    R        -0.768  -0.842  -0.717  -0.779  -0.845  -0.659  -0.972  -1.022  -0.845
27    H         1.053   1.082   1.139   1.314   1.356   1.419   1.110   1.148   1.230
28    C        -0.322  -0.580  -0.673   0.088  -0.309  -0.563  -0.315  -0.655  -0.783
29    A         0.349   0.175   0.061   0.330   0.116  -0.036   0.343   0.074  -0.149
30    E        -0.322  -0.580  -0.673  -0.009  -0.360  -0.545  -0.315  -0.655  -0.783
31    I        -0.322  -0.423  -0.645  -0.170  -0.325  -0.770  -0.315  -0.445  -0.746
32    S         0.002  -0.123  -0.043  -0.149  -0.376  -0.262  -0.205  -0.435  -0.336
33    D         1.053   1.082   1.139   1.241   1.277   1.355   1.110   1.148   1.230
34    P         1.053   1.082   1.139   1.095   1.135   1.225   1.110   1.148   1.230
35    T        -0.183  -0.197  -0.056  -0.373  -0.393  -0.167  -0.534  -0.571  -0.359
36    M         0.002  -0.123  -0.043   0.093  -0.157  -0.080  -0.205  -0.435  -0.336
37    L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
38    L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
39    T        -1.294  -1.397  -1.226  -1.386  -1.527  -1.298  -1.301  -1.357  -1.131
40    T        -0.630  -0.623  -0.687  -0.699  -0.651  -0.804  -0.753  -0.715  -0.804
41    E        -1.740  -1.659  -1.597  -1.715  -1.587  -1.467  -1.520  -1.415  -1.283
42    K        -2.186  -2.146  -1.932  -1.981  -1.931  -1.590  -1.739  -1.671  -1.408
43    D         0.349   0.254   0.064   0.621   0.494   0.165   0.343   0.198  -0.143
44    L        -0.183  -0.109  -0.036  -0.598  -0.481  -0.333  -0.534  -0.410  -0.322
45    A        -1.416  -1.261  -1.219  -1.354  -1.133  -1.082  -1.411  -1.239  -1.126
46    H        -1.862  -1.799  -1.618  -1.693  -1.628  -1.329  -1.630  -1.544  -1.300
47    A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
48    R        -0.630  -0.656  -0.677  -0.613  -0.645  -0.719  -0.753  -0.756  -0.789
49    E        -2.064  -1.842  -1.904  -1.678  -1.389  -1.453  -1.630  -1.416  -1.388
50    I        -1.416  -1.444  -1.236  -1.515  -1.603  -1.280  -1.411  -1.401  -1.141
51    I        -0.630  -0.648  -0.711  -0.704  -0.848  -0.946  -0.753  -0.820  -0.837
52    S        -1.740  -1.823  -1.624  -1.651  -1.768  -1.497  -1.520  -1.553  -1.304
53    A        -1.862  -1.775  -1.616  -1.796  -1.643  -1.434  -1.630  -1.523  -1.299
54    Y         0.349   0.357   0.079   0.715   0.728   0.332   0.343   0.353  -0.116
55    R        -0.768  -0.857  -0.714  -0.814  -0.933  -0.725  -0.972  -1.044  -0.842
56    H        -1.294  -1.397  -1.226  -1.123  -1.276  -1.043  -1.301  -1.357  -1.131
57    G         1.053   1.082   1.139   1.063   1.107   1.196   1.110   1.148   1.230
58    E        -1.740  -1.823  -1.624  -1.557  -1.655  -1.373  -1.520  -1.553  -1.304
59    L        -1.334  -1.236  -1.227  -1.554  -1.365  -1.303  -1.323  -1.214  -1.132
60    K        -1.538  -1.541  -1.591  -1.372  -1.415  -1.535  -1.301  -1.295  -1.277
61    E        -2.510  -2.439  -2.212  -2.107  -2.029  -1.729  -1.849  -1.762  -1.493
62    T        -0.768  -0.802  -0.704  -0.834  -0.861  -0.766  -0.972  -0.963  -0.826
63    T        -0.322  -0.398  -0.646  -0.182  -0.273  -0.653  -0.315  -0.429  -0.747
64    P         0.349   0.175   0.061   0.495   0.271   0.089   0.343   0.074  -0.149
65    E        -0.630  -0.777  -0.716  -0.493  -0.735  -0.656  -0.753  -0.943  -0.843
66    F        -0.768  -0.802  -0.704  -1.069  -1.130  -0.948  -0.972  -0.963  -0.826
67    W         1.053   1.082   1.139   1.321   1.358   1.426   1.110   1.148   1.230
68    R        -1.214  -1.306  -1.212  -0.963  -1.076  -0.955  -1.191  -1.272  -1.118
69    A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
70    K         1.053   1.082   1.139   1.081   1.129   1.212   1.110   1.148   1.230
71    K         0.002   0.060  -0.005  -0.012   0.082  -0.051  -0.205  -0.115  -0.266
72    Q        -1.294  -1.397  -1.226  -1.369  -1.538  -1.291  -1.301  -1.357  -1.131
73    L         0.002  -0.123  -0.043  -0.371  -0.618  -0.468  -0.205  -0.435  -0.336
74    D         1.053   1.082   1.139   1.241   1.277   1.355   1.110   1.148   1.230
75    S         1.053   1.082   1.139   0.981   1.026   1.123   1.110   1.148   1.230
76    T         1.053   1.082   1.139   1.032   1.083   1.169   1.110   1.148   1.230
77    V        -0.183  -0.037  -0.010  -0.717  -0.455  -0.406  -0.534  -0.281  -0.276
78    H         1.053   1.082   1.139   1.314   1.356   1.419   1.110   1.148   1.230
79    P         1.053   1.082   1.139   1.095   1.135   1.225   1.110   1.148   1.230
80    D         1.053   1.082   1.139   1.241   1.277   1.355   1.110   1.148   1.230
81    T         0.349   0.357   0.079   0.420   0.447   0.037   0.343   0.353  -0.116
82    G         0.349   0.175   0.061   0.446   0.218   0.019   0.343   0.074  -0.149
83    K         0.349   0.508   0.088   0.576   0.775   0.175   0.343   0.563  -0.101
84    T        -0.630  -0.777  -0.716  -0.652  -0.879  -0.787  -0.753  -0.943  -0.843
85    V         1.053   1.082   1.139   0.918   0.960   1.067   1.110   1.148   1.230
86    L        -0.630  -0.484  -0.657  -0.580  -0.314  -0.631  -0.753  -0.530  -0.762
87    L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
88    P         1.053   1.082   1.139   1.095   1.135   1.225   1.110   1.148   1.230
89    F         1.053   1.082   1.139   1.194   1.230   1.313   1.110   1.148   1.230
90    R         1.053   1.082   1.139   1.156   1.195   1.279   1.110   1.148   1.230
91    M         1.053   1.082   1.139   1.231   1.269   1.346   1.110   1.148   1.230
92    S         1.053   1.082   1.139   0.981   1.026   1.123   1.110   1.148   1.230
93    S        -0.183  -0.193  -0.056  -0.313  -0.300  -0.074  -0.534  -0.563  -0.360
94    N        -1.214  -1.177  -1.208  -0.819  -0.829  -0.854  -1.191  -1.168  -1.115
95    V         1.053   1.082   1.139   0.918   0.960   1.067   1.110   1.148   1.230
96    L         0.349   0.463   0.087   0.179   0.319  -0.157   0.343   0.502  -0.103
97    S         0.349   0.175   0.061   0.357   0.127  -0.069   0.343   0.074  -0.149
98    N         1.053   1.082   1.139   1.112   1.159   1.239   1.110   1.148   1.230
99    L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
100   V         0.349   0.463   0.087   0.308   0.452  -0.041   0.343   0.502  -0.103
101   V         1.053   1.082   1.139   0.918   0.960   1.067   1.110   1.148   1.230
102   T         1.053   1.082   1.139   1.032   1.083   1.169   1.110   1.148   1.230
103   V        -0.183  -0.079  -0.028  -0.598  -0.405  -0.338  -0.534  -0.356  -0.308
104   G         1.053   1.082   1.139   1.063   1.107   1.196   1.110   1.148   1.230
105   M         1.053   1.082   1.139   1.231   1.269   1.346   1.110   1.148   1.230
106   L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
107   T         0.349   0.175   0.061   0.438   0.228   0.054   0.343   0.074  -0.149
108   P         1.053   1.082   1.139   1.095   1.135   1.225   1.110   1.148   1.230
109   G        -0.183  -0.119  -0.042  -0.353  -0.236  -0.146  -0.534  -0.427  -0.333
110   L         0.349   0.463   0.087   0.200   0.336  -0.105   0.343   0.502  -0.103
111   G         1.053   1.082   1.139   1.063   1.107   1.196   1.110   1.148   1.230
112   T        -0.322  -0.343  -0.643  -0.185  -0.205  -0.654  -0.315  -0.345  -0.743
113   A         0.349   0.254   0.064   0.318   0.206  -0.061   0.343   0.198  -0.143
114   G         1.053   1.082   1.139   1.063   1.107   1.196   1.110   1.148   1.230
115   T         1.053   1.082   1.139   1.032   1.083   1.169   1.110   1.148   1.230
116   V        -0.970  -0.929  -0.753  -1.448  -1.367  -1.058  -1.191  -1.124  -0.887
117   F         0.349   0.254   0.064   0.555   0.422   0.075   0.343   0.198  -0.143
118   W         1.053   1.082   1.139   1.321   1.358   1.426   1.110   1.148   1.230
119   Q         1.053   1.082   1.139   1.235   1.268   1.350   1.110   1.148   1.230
120   W        -0.890  -0.849  -0.744  -0.852  -0.805  -0.715  -1.082  -1.019  -0.875
121   A         0.349   0.175   0.061   0.330   0.116  -0.036   0.343   0.074  -0.149
122   N         1.053   1.082   1.139   1.112   1.159   1.239   1.110   1.148   1.230
123   Q         1.053   1.082   1.139   1.235   1.268   1.350   1.110   1.148   1.230
124   S         1.053   1.082   1.139   0.981   1.026   1.123   1.110   1.148   1.230
125   L         0.349   0.175   0.061   0.152  -0.097  -0.272   0.343   0.074  -0.149
126   N         1.053   1.082   1.139   1.112   1.159   1.239   1.110   1.148   1.230
127   V         1.053   1.082   1.139   0.918   0.960   1.067   1.110   1.148   1.230
128   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
129   V        -0.768  -0.854  -0.718  -0.952  -1.027  -0.795  -0.972  -1.040  -0.847
130   N         1.053   1.082   1.139   1.112   1.159   1.239   1.110   1.148   1.230
131   S        -1.294  -1.260  -1.211  -1.368  -1.289  -1.172  -1.301  -1.241  -1.118
132   A         0.349   0.254   0.064   0.293   0.171  -0.131   0.343   0.198  -0.143
133   N         1.053   1.082   1.139   1.112   1.159   1.239   1.110   1.148   1.230
134   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
135   N         1.053   1.082   1.139   1.112   1.159   1.239   1.110   1.148   1.230
136   K         1.053   1.082   1.139   1.081   1.129   1.212   1.110   1.148   1.230
137   S         1.053   1.082   1.139   0.981   1.026   1.123   1.110   1.148   1.230
138   H        -0.630  -0.777  -0.716  -0.429  -0.702  -0.675  -0.753  -0.943  -0.843
139   P         0.349   0.175   0.061   0.501   0.278   0.105   0.343   0.074  -0.149
140   M        -0.183  -0.037  -0.010  -0.538  -0.324  -0.242  -0.534  -0.281  -0.276
141   S        -0.183  -0.180  -0.054  -0.485  -0.485  -0.281  -0.534  -0.539  -0.355
142   T        -0.322  -0.580  -0.673  -0.198  -0.570  -0.735  -0.315  -0.655  -0.783
143   S        -1.862  -1.822  -1.618  -1.877  -1.807  -1.487  -1.630  -1.558  -1.300
144   Q         0.349   0.254   0.064   0.618   0.489   0.167   0.343   0.198  -0.143
145   L        -0.768  -0.854  -0.718  -1.045  -1.107  -0.853  -0.972  -1.040  -0.847
146   L        -1.740  -1.736  -1.603  -1.839  -1.822  -1.704  -1.520  -1.486  -1.289
147   T        -0.322  -0.580  -0.673  -0.167  -0.509  -0.658  -0.315  -0.655  -0.783
148   N        -0.183  -0.197  -0.056  -0.396  -0.458  -0.233  -0.534  -0.571  -0.359
149   Y         1.053   1.082   1.139   1.300   1.336   1.407   1.110   1.148   1.230
150   A        -1.416  -1.426  -1.228  -1.520  -1.474  -1.202  -1.411  -1.384  -1.134
151   A        -1.416  -1.417  -1.224  -1.521  -1.483  -1.222  -1.411  -1.374  -1.130
152   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
153   V         1.053   1.082   1.139   0.918   0.960   1.067   1.110   1.148   1.230
154   T        -0.630  -0.750  -0.711  -0.699  -0.888  -0.852  -0.753  -0.901  -0.837
155   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
156   S         1.053   1.082   1.139   0.981   1.026   1.123   1.110   1.148   1.230
157   C         1.053   1.082   1.139   1.348   1.386   1.450   1.110   1.148   1.230
158   G        -0.183  -0.109  -0.036  -0.439  -0.303  -0.215  -0.534  -0.410  -0.322
159   V         1.053   1.082   1.139   0.918   0.960   1.067   1.110   1.148   1.230
160   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
161   L        -0.630  -0.774  -0.710  -0.942  -1.151  -1.024  -0.753  -0.923  -0.835
162   G         1.053   1.082   1.139   1.063   1.107   1.196   1.110   1.148   1.230
163   L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
164   N         1.053   1.082   1.139   1.112   1.159   1.239   1.110   1.148   1.230
165   N        -1.538  -1.453  -1.243  -1.775  -1.637  -1.325  -1.520  -1.409  -1.147
166   L        -0.630  -0.755  -0.711  -0.899  -1.088  -0.985  -0.753  -0.909  -0.838
167   V         1.053   1.082   1.139   0.918   0.960   1.067   1.110   1.148   1.230
168   P         1.053   1.082   1.139   1.095   1.135   1.225   1.110   1.148   1.230
169   R         0.349   0.499   0.086   0.539   0.723   0.140   0.343   0.551  -0.105
170   L         0.349   0.175   0.061   0.200  -0.018  -0.142   0.343   0.074  -0.149
171   K         0.349   0.175   0.061   0.469   0.247   0.045   0.343   0.074  -0.149
172   N        -1.334  -1.280  -1.216  -1.310  -1.216  -1.076  -1.323  -1.238  -1.121
173   I        -0.630  -0.484  -0.657  -0.899  -0.675  -0.922  -0.753  -0.530  -0.762
174   S        -1.538  -1.387  -1.571  -1.388  -1.208  -1.440  -1.301  -1.137  -1.260
175   P        -0.322  -0.400  -0.641  -0.172  -0.302  -0.716  -0.315  -0.432  -0.741
176   H        -0.970  -0.817  -0.727  -1.096  -0.891  -0.731  -1.191  -0.986  -0.856
177   S        -0.630  -0.659  -0.694  -0.727  -0.783  -0.876  -0.753  -0.792  -0.816
178   K        -0.183  -0.154  -0.047  -0.304  -0.264  -0.115  -0.534  -0.492  -0.343
179   L        -0.768  -0.823  -0.707  -1.042  -1.131  -0.914  -0.972  -0.994  -0.832
180   I         0.002  -0.084  -0.034  -0.043  -0.221  -0.196  -0.205  -0.366  -0.320
181   L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
182   G         0.349   0.254   0.064   0.432   0.310  -0.014   0.343   0.198  -0.143
183   R         1.053   1.082   1.139   1.156   1.195   1.279   1.110   1.148   1.230
184   L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
185   V         0.349   0.175   0.061   0.294   0.061  -0.121   0.343   0.074  -0.149
186   P         1.053   1.082   1.139   1.095   1.135   1.225   1.110   1.148   1.230
187   F         1.053   1.082   1.139   1.194   1.230   1.313   1.110   1.148   1.230
188   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
189   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
190   V         1.053   1.082   1.139   0.918   0.960   1.067   1.110   1.148   1.230
191   V         0.002  -0.123  -0.043  -0.246  -0.496  -0.372  -0.205  -0.435  -0.336
192   S         1.053   1.082   1.139   0.981   1.026   1.123   1.110   1.148   1.230
193   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
194   G         1.053   1.082   1.139   1.063   1.107   1.196   1.110   1.148   1.230
195   I        -0.768  -0.812  -0.713  -0.965  -1.053  -0.896  -0.972  -0.997  -0.840
196   V         0.002  -0.123  -0.043  -0.289  -0.566  -0.448  -0.205  -0.435  -0.336
197   N         1.053   1.082   1.139   1.112   1.159   1.239   1.110   1.148   1.230
198   V         1.053   1.082   1.139   0.918   0.960   1.067   1.110   1.148   1.230
199   F         1.053   1.082   1.139   1.194   1.230   1.313   1.110   1.148   1.230
200   L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
201   M         1.053   1.082   1.139   1.231   1.269   1.346   1.110   1.148   1.230
202   R         1.053   1.082   1.139   1.156   1.195   1.279   1.110   1.148   1.230
203   G        -0.183  -0.109  -0.036  -0.439  -0.303  -0.215  -0.534  -0.410  -0.322
204   N        -0.630  -0.391  -0.657  -0.497  -0.133  -0.568  -0.753  -0.418  -0.763
205   E         1.053   1.082   1.139   1.194   1.237   1.313   1.110   1.148   1.230
206   I        -0.768  -0.813  -0.714  -0.975  -1.057  -0.855  -0.972  -0.998  -0.842
207   R        -0.630  -0.413  -0.663  -0.512  -0.206  -0.559  -0.753  -0.461  -0.771
208   K        -0.953  -1.185  -1.198  -0.703  -1.024  -1.063  -0.863  -1.121  -1.101
209   G         1.053   1.082   1.139   1.063   1.107   1.196   1.110   1.148   1.230
210   I         1.053   1.082   1.139   1.128   1.174   1.254   1.110   1.148   1.230
211   S        -1.740  -1.638  -1.612  -1.689  -1.503  -1.491  -1.520  -1.410  -1.295
212   V         1.053   1.082   1.139   0.918   0.960   1.067   1.110   1.148   1.230
213   F        -0.242  -0.197  -0.056  -0.251  -0.183   0.026  -0.643  -0.571  -0.359
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   D        -0.322  -0.423  -0.645   0.037  -0.097  -0.464  -0.315  -0.445  -0.746
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   S        -1.862  -1.786  -1.613  -1.813  -1.688  -1.435  -1.630  -1.529  -1.297
234   N        -1.740  -1.661  -1.600  -1.459  -1.355  -1.235  -1.520  -1.434  -1.286
235   G        -0.322  -0.423  -0.645  -0.184  -0.326  -0.702  -0.315  -0.445  -0.746
236   D        -1.214  -0.968  -1.169  -0.978  -0.618  -0.934  -1.191  -0.887  -1.072
237   E        -0.630  -0.728  -0.716  -0.542  -0.758  -0.745  -0.753  -0.901  -0.843
238   V         0.002  -0.123  -0.043  -0.289  -0.566  -0.448  -0.205  -0.435  -0.336
239   G         1.053   1.082   1.139   1.063   1.107   1.196   1.110   1.148   1.230
240   K        -0.953  -0.808  -1.156  -0.707  -0.501  -1.010  -0.863  -0.683  -1.058
241   S         1.053   1.082   1.139   0.981   1.026   1.123   1.110   1.148   1.230
242   K         0.349   0.447   0.083   0.487   0.614   0.128   0.343   0.480  -0.111
243   K        -0.322  -0.147  -0.625  -0.126   0.104  -0.566  -0.315  -0.084  -0.720
244   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
245   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
246   F        -0.953  -0.894  -1.168  -0.622  -0.560  -0.993  -0.863  -0.791  -1.070
247   M        -1.214  -1.010  -1.193  -0.886  -0.640  -0.882  -1.191  -0.975  -1.100
248   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
249   V         1.053   1.082   1.139   0.918   0.960   1.067   1.110   1.148   1.230
250   G        -0.630  -0.563  -0.690  -0.707  -0.624  -0.848  -0.753  -0.674  -0.809
251   E         1.053   1.082   1.139   1.194   1.237   1.313   1.110   1.148   1.230
252   T         1.053   1.082   1.139   1.032   1.083   1.169   1.110   1.148   1.230
253   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
254   L        -1.214  -1.142  -1.192  -1.511  -1.408  -1.426  -1.191  -1.085  -1.097
255   S         1.053   1.082   1.139   0.981   1.026   1.123   1.110   1.148   1.230
256   R         1.053   1.082   1.139   1.156   1.195   1.279   1.110   1.148   1.230
257   V         0.349   0.463   0.087   0.308   0.452  -0.041   0.343   0.502  -0.103
258   I        -0.322  -0.328  -0.640  -0.160  -0.184  -0.734  -0.315  -0.328  -0.739
259   N         1.053   1.082   1.139   1.112   1.159   1.239   1.110   1.148   1.230
260   A         0.349   0.254   0.064   0.293   0.171  -0.131   0.343   0.198  -0.143
261   T        -0.630  -0.728  -0.716  -0.726  -0.925  -0.915  -0.753  -0.901  -0.843
262   P         1.053   1.082   1.139   1.095   1.135   1.225   1.110   1.148   1.230
263   T        -0.890  -0.727  -0.705  -1.060  -0.773  -0.805  -1.082  -0.856  -0.826
264   M         1.053   1.082   1.139   1.231   1.269   1.346   1.110   1.148   1.230
265   V         0.349   0.357   0.079   0.278   0.294  -0.130   0.343   0.353  -0.116
266   I         0.349   0.357   0.079   0.488   0.507   0.047   0.343   0.353  -0.116
267   P         1.053   1.082   1.139   1.095   1.135   1.225   1.110   1.148   1.230
268   P         1.053   1.082   1.139   1.095   1.135   1.225   1.110   1.148   1.230
269   L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
270   I         0.002  -0.123  -0.043  -0.043  -0.303  -0.219  -0.205  -0.435  -0.336
271   L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
272   V         0.349   0.175   0.061   0.324   0.108  -0.041   0.343   0.074  -0.149
273   R        -0.242  -0.189  -0.053  -0.434  -0.337  -0.130  -0.643  -0.555  -0.354
274   L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
275   Q         1.053   1.082   1.139   1.235   1.268   1.350   1.110   1.148   1.230
276   R        -1.214  -1.098  -1.180  -1.122  -0.953  -1.076  -1.191  -1.031  -1.084
277   G        -1.416  -1.371  -1.215  -1.532  -1.401  -1.191  -1.411  -1.322  -1.120
278   -        -1.955  -1.863  -1.636  -1.831  -1.689  -1.383  -1.696  -1.584  -1.314
279   V        -0.890  -0.855  -0.739  -0.879  -0.802  -0.670  -1.082  -1.039  -0.870
280   L         0.349   0.357   0.079   0.200   0.215  -0.115   0.343   0.353  -0.116
281   K         0.002  -0.084  -0.034  -0.012  -0.159  -0.103  -0.205  -0.366  -0.320
282   G        -1.740  -1.662  -1.604  -1.689  -1.588  -1.489  -1.520  -1.435  -1.290
283   K        -0.630  -0.777  -0.716  -0.577  -0.798  -0.710  -0.753  -0.943  -0.843
284   S        -0.630  -0.728  -0.716  -0.704  -0.877  -0.828  -0.753  -0.901  -0.843
285   L        -1.214  -1.086  -1.193  -1.133  -0.926  -1.134  -1.191  -1.025  -1.097
286   G        -1.269  -1.303  -1.228  -1.233  -1.281  -1.213  -1.228  -1.251  -1.132
287   V        -2.064  -2.079  -1.928  -1.908  -1.986  -1.675  -1.630  -1.619  -1.405
288   Q        -0.970  -0.939  -0.753  -0.999  -0.985  -0.709  -1.191  -1.137  -0.887
289   T        -0.630  -0.678  -0.700  -0.669  -0.746  -0.803  -0.753  -0.821  -0.824
290   L        -1.416  -1.282  -1.228  -1.698  -1.480  -1.352  -1.411  -1.267  -1.134
291   A        -1.214  -1.129  -1.184  -1.381  -1.215  -1.303  -1.191  -1.065  -1.088
292   N         1.053   1.082   1.139   1.112   1.159   1.239   1.110   1.148   1.230
293   L        -0.322  -0.147  -0.625  -0.396  -0.179  -0.756  -0.315  -0.084  -0.720
294   G         1.053   1.082   1.139   1.063   1.107   1.196   1.110   1.148   1.230
295   L         0.349   0.463   0.087   0.152   0.297  -0.225   0.343   0.502  -0.103
296   I         1.053   1.082   1.139   1.128   1.174   1.254   1.110   1.148   1.230
297   S        -1.862  -1.802  -1.617  -2.072  -2.003  -1.713  -1.630  -1.546  -1.300
298   V        -1.416  -1.306  -1.228  -1.829  -1.701  -1.533  -1.411  -1.286  -1.134
299   T         0.349   0.357   0.079   0.392   0.416  -0.035   0.343   0.353  -0.116
300   M        -0.630  -0.405  -0.651  -0.677  -0.347  -0.718  -0.753  -0.435  -0.754
301   F        -0.768  -0.813  -0.716  -0.904  -0.979  -0.785  -0.972  -0.999  -0.844
302   S        -1.416  -1.348  -1.231  -1.652  -1.548  -1.364  -1.411  -1.330  -1.137
303   A         0.349   0.254   0.064   0.284   0.158  -0.155   0.343   0.198  -0.143
304   L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
305   P         1.053   1.082   1.139   1.095   1.135   1.225   1.110   1.148   1.230
306   F         0.002  -0.123  -0.043  -0.016  -0.313  -0.237  -0.205  -0.435  -0.336
307   A         1.053   1.082   1.139   0.924   0.968   1.072   1.110   1.148   1.230
308   L         0.349   0.175   0.061   0.184  -0.043  -0.186   0.343   0.074  -0.149
309   G         0.002  -0.025  -0.029  -0.194  -0.243  -0.262  -0.205  -0.260  -0.310
310   I        -0.768  -0.813  -0.709  -0.965  -1.041  -0.887  -0.972  -0.998  -0.836
311   F         1.053   1.082   1.139   1.194   1.230   1.313   1.110   1.148   1.230
312   P         1.053   1.082   1.139   1.095   1.135   1.225   1.110   1.148   1.230
313   Q         0.349   0.175   0.061   0.596   0.340   0.103   0.343   0.074  -0.149
314   R        -1.214  -1.167  -1.190  -1.007  -0.931  -0.948  -1.191  -1.117  -1.095
315   Q        -0.768  -0.842  -0.717  -0.679  -0.761  -0.585  -0.972  -1.022  -0.845
316   A        -2.186  -1.992  -1.931  -2.151  -1.811  -1.752  -1.739  -1.547  -1.407
317   I         0.002   0.126   0.016  -0.081   0.133  -0.134  -0.205  -0.006  -0.228
318   H        -2.064  -1.842  -1.904  -1.907  -1.599  -1.683  -1.630  -1.416  -1.388
319   L        -1.862  -1.842  -1.616  -2.245  -2.151  -1.802  -1.630  -1.568  -1.299
320   N        -2.186  -2.152  -1.933  -1.986  -1.892  -1.627  -1.739  -1.674  -1.408
321   K        -1.214  -1.133  -1.184  -1.149  -0.997  -1.077  -1.191  -1.070  -1.089
322   L         1.053   1.082   1.139   0.795   0.833   0.957   1.110   1.148   1.230
323   E         1.053   1.082   1.139   1.194   1.237   1.313   1.110   1.148   1.230
324   P        -1.538  -1.387  -1.571  -1.259  -1.071  -1.333  -1.301  -1.137  -1.260
325   E        -1.214  -1.169  -1.193  -0.986  -0.910  -0.941  -1.191  -1.124  -1.097
326   L        -0.183  -0.037  -0.010  -0.417  -0.119  -0.144  -0.534  -0.281  -0.276
327   H        -0.630  -0.636  -0.692  -0.366  -0.380  -0.508  -0.753  -0.756  -0.812
328   G        -1.538  -1.530  -1.578  -1.237  -1.215  -1.285  -1.301  -1.286  -1.266
329   K        -0.768  -0.746  -0.702  -1.092  -1.030  -0.911  -0.972  -0.896  -0.824
330   K        -0.953  -0.969  -1.163  -0.771  -0.792  -1.141  -0.863  -0.875  -1.065
331   D        -0.322  -0.423  -0.645   0.029  -0.112  -0.481  -0.315  -0.445  -0.746
332   K        -0.435  -0.442  -0.659  -0.289  -0.292  -0.645  -0.464  -0.480  -0.765
333   D        -0.824  -0.883  -0.717  -0.836  -0.914  -0.681  -1.037  -1.071  -0.845
334   G        -0.435  -0.506  -0.665  -0.292  -0.391  -0.630  -0.464  -0.573  -0.773
335   K        -0.837  -0.921  -0.744  -0.902  -0.994  -0.732  -1.033  -1.113  -0.876
336   P        -0.837  -0.709  -0.722  -0.833  -0.642  -0.643  -1.033  -0.851  -0.849
337   I         0.211   0.275   0.033   0.269   0.362  -0.067   0.136   0.231  -0.198
338   E        -1.103  -1.219  -1.213  -0.887  -1.126  -1.153  -1.037  -1.170  -1.117
339   K        -2.186  -2.080  -1.929  -1.999  -1.860  -1.638  -1.739  -1.621  -1.406
340   V        -0.183  -0.109  -0.036  -0.671  -0.535  -0.429  -0.534  -0.410  -0.322
341   Y        -1.294  -1.304  -1.212  -1.059  -1.077  -0.954  -1.301  -1.269  -1.117
342   F         1.053   1.082   1.139   1.194   1.230   1.313   1.110   1.148   1.230
343   N         1.053   1.082   1.139   1.112   1.159   1.239   1.110   1.148   1.230
344   R         1.053   1.082   1.139   1.156   1.195   1.279   1.110   1.148   1.230
345   G         1.053   1.082   1.139   1.063   1.107   1.196   1.110   1.148   1.230
346   I        -0.630  -0.728  -0.695  -0.562  -0.729  -0.720  -0.753  -0.857  -0.816
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12029
Output conservation file - output/Q12029
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
