1     M         2.293   2.309   2.382   2.626   2.652   2.776   2.588   2.612   2.732
2     L         0.865   0.876   0.813   0.616   0.610   0.542   0.784   0.801   0.678
3     V        -1.229  -1.222  -1.198  -1.221  -1.215  -1.168  -1.020  -1.010  -0.964
4     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     L        -0.348  -0.382  -0.373  -0.511  -0.575  -0.522  -0.419  -0.463  -0.444
7     L        -0.348  -0.344  -0.358  -0.637  -0.653  -0.645  -0.419  -0.410  -0.422
8     R        -0.348  -0.297  -0.342  -0.052   0.120  -0.028  -0.419  -0.348  -0.402
9     V        -0.348  -0.297  -0.342  -0.536  -0.482  -0.514  -0.419  -0.348  -0.402
10    I         0.865   0.944   0.830   0.587   0.679   0.533   0.784   0.916   0.709
11    L         0.532   0.543   0.593   0.068   0.081   0.167   0.182   0.199   0.271
12    L         0.865   0.873   0.811   0.587   0.575   0.504   0.784   0.796   0.675
13    A        -0.348  -0.338  -0.354  -0.637  -0.647  -0.639  -0.419  -0.405  -0.417
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    S         0.865   0.876   0.813   0.909   0.923   0.831   0.784   0.801   0.678
24    M        -0.348  -0.338  -0.354  -0.511  -0.528  -0.500  -0.419  -0.405  -0.417
25    V        -0.348  -0.382  -0.373  -0.292  -0.299  -0.328  -0.419  -0.463  -0.444
26    F        -1.229  -1.222  -1.198  -0.905  -0.888  -0.843  -1.020  -1.010  -0.964
27    C        -1.229  -1.222  -1.198  -1.047  -1.061  -0.989  -1.020  -1.010  -0.964
28    A        -1.229  -1.222  -1.198  -0.961  -0.921  -0.901  -1.020  -1.010  -0.964
29    D        -0.348  -0.380  -0.370  -0.628  -0.707  -0.705  -0.419  -0.461  -0.440
30    I         0.865   0.944   0.830   0.587   0.679   0.533   0.784   0.916   0.709
31    L        -0.348  -0.299  -0.344  -0.474  -0.397  -0.478  -0.419  -0.350  -0.404
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    Q         0.532   0.541   0.592   0.172   0.258   0.259   0.182   0.194   0.268
34    L        -0.348  -0.380  -0.370  -0.540  -0.604  -0.551  -0.419  -0.461  -0.440
35    S        -0.498  -0.491  -0.455  -0.568  -0.565  -0.499  -0.619  -0.608  -0.553
36    Y        -0.498  -0.491  -0.455  -0.568  -0.579  -0.499  -0.619  -0.608  -0.553
37    S        -0.498  -0.491  -0.455  -0.749  -0.762  -0.684  -0.619  -0.608  -0.553
38    D        -1.229  -1.222  -1.198  -0.877  -0.854  -0.815  -1.020  -1.010  -0.964
39    D        -0.348  -0.382  -0.373  -0.487  -0.566  -0.548  -0.419  -0.463  -0.444
40    A        -1.229  -1.222  -1.198  -1.353  -1.371  -1.303  -1.020  -1.010  -0.964
41    K        -1.229  -1.222  -1.198  -1.226  -1.203  -1.173  -1.020  -1.010  -0.964
42    D        -0.348  -0.299  -0.344  -0.557  -0.475  -0.551  -0.419  -0.350  -0.404
43    A        -0.348  -0.338  -0.354  -0.009   0.014  -0.014  -0.419  -0.405  -0.417
44    I        -0.348  -0.344  -0.358  -0.246  -0.245  -0.257  -0.419  -0.410  -0.422
45    P        -0.348  -0.338  -0.354  -0.315  -0.323  -0.318  -0.419  -0.405  -0.417
46    L         2.293   2.309   2.382   2.005   2.005   2.139   2.588   2.612   2.732
47    G         0.865   0.873   0.811   1.001   1.037   0.913   0.784   0.796   0.675
48    T        -0.348  -0.380  -0.370  -0.414  -0.472  -0.454  -0.419  -0.461  -0.440
49    F        -0.348  -0.380  -0.370  -0.296  -0.384  -0.359  -0.419  -0.461  -0.440
50    E        -0.348  -0.380  -0.370  -0.234  -0.269  -0.257  -0.419  -0.461  -0.440
51    I        -1.229  -1.222  -1.198  -1.081  -1.074  -1.024  -1.020  -1.010  -0.964
52    D         0.865   0.873   0.811   0.917   0.947   0.836   0.784   0.796   0.675
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    S        -1.229  -1.222  -1.198  -1.170  -1.153  -1.115  -1.020  -1.010  -0.964
55    T        -0.348  -0.344  -0.358  -0.495  -0.486  -0.523  -0.419  -0.410  -0.422
56    S        -1.229  -1.222  -1.198  -1.237  -1.237  -1.184  -1.020  -1.010  -0.964
57    D        -0.348  -0.299  -0.344  -0.052   0.048  -0.046  -0.419  -0.350  -0.404
58    G        -0.498  -0.491  -0.455  -0.527  -0.519  -0.456  -0.619  -0.608  -0.553
59    N         0.865   0.813   0.793   0.990   0.894   0.866   0.784   0.691   0.642
60    V        -1.229  -1.222  -1.198  -1.231  -1.226  -1.178  -1.020  -1.010  -0.964
61    T         0.865   0.873   0.811   0.861   0.871   0.773   0.784   0.796   0.675
62    V        -0.348  -0.380  -0.370  -0.254  -0.234  -0.279  -0.419  -0.461  -0.440
63    T         0.865   0.813   0.793   0.891   0.807   0.780   0.784   0.691   0.642
64    T        -0.348  -0.382  -0.373  -0.410  -0.467  -0.454  -0.419  -0.463  -0.444
65    V        -0.348  -0.299  -0.344  -0.620  -0.571  -0.608  -0.419  -0.350  -0.404
66    N        -1.229  -1.222  -1.198  -0.984  -0.977  -0.925  -1.020  -1.010  -0.964
67    I         0.865   0.876   0.813   0.967   0.974   0.881   0.784   0.801   0.678
68    Q        -1.229  -1.222  -1.198  -1.175  -1.114  -1.121  -1.020  -1.010  -0.964
69    D         0.865   0.876   0.813   0.876   0.898   0.788   0.784   0.801   0.678
70    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    G         2.293   2.309   2.382   2.450   2.498   2.595   2.588   2.612   2.732
75    E        -0.348  -0.380  -0.370  -0.234  -0.269  -0.257  -0.419  -0.461  -0.440
76    Y         2.293   2.309   2.382   2.494   2.516   2.640   2.588   2.612   2.732
77    C         0.865   0.873   0.811   1.171   1.188   1.064   0.784   0.796   0.675
78    L        -1.229  -1.222  -1.198  -1.231  -1.215  -1.178  -1.020  -1.010  -0.964
79    N        -0.498  -0.492  -0.455  -0.310  -0.282  -0.234  -0.619  -0.610  -0.553
80    A         0.532   0.543   0.594   0.394   0.429   0.495   0.182   0.199   0.272
81    Q        -0.348  -0.297  -0.342  -0.339  -0.214  -0.325  -0.419  -0.348  -0.402
82    I        -1.229  -1.222  -1.198  -1.023  -1.007  -0.964  -1.020  -1.010  -0.964
83    E        -0.348  -0.382  -0.373  -0.304  -0.299  -0.341  -0.419  -0.463  -0.444
84    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    K        -1.229  -1.222  -1.198  -1.560  -1.575  -1.515  -1.020  -1.010  -0.964
86    L        -0.348  -0.338  -0.354  -0.292  -0.267  -0.311  -0.419  -0.405  -0.417
87    D        -1.229  -1.222  -1.198  -1.095  -1.085  -1.039  -1.020  -1.010  -0.964
88    M        -1.229  -1.222  -1.198  -1.190  -1.223  -1.136  -1.020  -1.010  -0.964
89    P        -0.348  -0.297  -0.342  -0.273  -0.189  -0.257  -0.419  -0.348  -0.402
90    C         2.293   2.309   2.382   2.695   2.724   2.847   2.588   2.612   2.732
91    F         2.293   2.309   2.382   2.565   2.590   2.713   2.588   2.612   2.732
92    S        -0.348  -0.380  -0.370  -0.257  -0.319  -0.278  -0.419  -0.461  -0.440
93    Y         0.865   0.873   0.811   1.110   1.122   1.038   0.784   0.796   0.675
94    M        -1.229  -1.222  -1.198  -1.226  -1.248  -1.173  -1.020  -1.010  -0.964
95    K         0.865   0.873   0.811   0.808   0.817   0.748   0.784   0.796   0.675
96    L        -0.348  -0.344  -0.358  -0.637  -0.653  -0.645  -0.419  -0.410  -0.422
97    R        -1.229  -1.222  -1.198  -1.170  -1.178  -1.115  -1.020  -1.010  -0.964
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    T        -1.229  -1.222  -1.198  -1.283  -1.212  -1.232  -1.020  -1.010  -0.964
100   P        -0.348  -0.380  -0.370  -0.288  -0.357  -0.350  -0.419  -0.461  -0.440
101   L        -0.348  -0.380  -0.370  -0.418  -0.470  -0.413  -0.419  -0.461  -0.440
102   K        -1.229  -1.222  -1.198  -1.226  -1.195  -1.173  -1.020  -1.010  -0.964
103   Y         0.865   0.813   0.793   1.027   0.937   0.901   0.784   0.691   0.642
104   D        -1.229  -1.222  -1.198  -1.358  -1.352  -1.308  -1.020  -1.010  -0.964
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   L         2.293   2.309   2.382   2.005   2.005   2.139   2.588   2.612   2.732
107   I        -1.229  -1.222  -1.198  -1.195  -1.217  -1.141  -1.020  -1.010  -0.964
108   V         0.865   0.873   0.811   0.802   0.807   0.683   0.784   0.796   0.675
109   D        -0.348  -0.382  -0.373  -0.234  -0.270  -0.257  -0.419  -0.463  -0.444
110   V         0.865   0.813   0.793   0.802   0.696   0.646   0.784   0.691   0.642
111   D        -0.348  -0.299  -0.344  -0.434  -0.358  -0.445  -0.419  -0.350  -0.404
112   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   D         2.293   2.309   2.382   2.332   2.364   2.474   2.588   2.612   2.732
114   N        -0.348  -0.338  -0.354  -0.430  -0.425  -0.447  -0.419  -0.405  -0.417
115   E        -1.229  -1.222  -1.198  -1.226  -1.217  -1.173  -1.020  -1.010  -0.964
116   V        -0.348  -0.382  -0.373  -0.478  -0.550  -0.543  -0.419  -0.463  -0.444
117   K        -1.229  -1.222  -1.198  -1.310  -1.289  -1.259  -1.020  -1.010  -0.964
118   Q        -1.229  -1.222  -1.198  -0.800  -0.731  -0.736  -1.020  -1.010  -0.964
119   V        -0.348  -0.299  -0.344  -0.536  -0.484  -0.516  -0.419  -0.350  -0.404
120   S         0.865   0.876   0.813   0.861   0.868   0.771   0.784   0.801   0.678
121   L        -1.229  -1.222  -1.198  -0.994  -0.963  -0.935  -1.020  -1.010  -0.964
122   S        -0.348  -0.344  -0.358  -0.129  -0.130  -0.117  -0.419  -0.410  -0.422
123   Y        -0.498  -0.492  -0.455  -0.358  -0.355  -0.283  -0.619  -0.610  -0.553
124   D         0.676   0.675   0.677   0.586   0.581   0.581   0.450   0.444   0.429
125   E         0.676   0.716   0.692   0.514   0.584   0.526   0.450   0.519   0.457
126   T        -0.498  -0.492  -0.455  -0.534  -0.530  -0.464  -0.619  -0.610  -0.553
127   N        -0.498  -0.492  -0.455  -0.491  -0.498  -0.419  -0.619  -0.610  -0.553
128   D         0.676   0.675   0.677   0.586   0.581   0.581   0.450   0.444   0.429
129   A        -0.348  -0.338  -0.354  -0.296  -0.265  -0.311  -0.419  -0.405  -0.417
130   I        -0.348  -0.380  -0.370  -0.327  -0.394  -0.371  -0.419  -0.461  -0.440
131   T        -0.348  -0.382  -0.373  -0.414  -0.478  -0.459  -0.419  -0.463  -0.444
132   A        -0.348  -0.382  -0.373  -0.410  -0.500  -0.464  -0.419  -0.463  -0.444
133   T        -1.229  -1.222  -1.198  -1.440  -1.445  -1.392  -1.020  -1.010  -0.964
134   V        -0.348  -0.382  -0.373  -0.422  -0.495  -0.477  -0.419  -0.463  -0.444
135   R        -0.348  -0.382  -0.373  -0.144  -0.206  -0.206  -0.419  -0.463  -0.444
136   Y        -1.229  -1.222  -1.198  -1.336  -1.346  -1.286  -1.020  -1.010  -0.964
137   P        -0.348  -0.382  -0.373  -0.189  -0.261  -0.242  -0.419  -0.463  -0.444
138   E        -0.348  -0.344  -0.358  -0.311  -0.286  -0.324  -0.419  -0.410  -0.422
139   A        -1.229  -1.222  -1.198  -0.980  -0.984  -0.920  -1.020  -1.010  -0.964
140   G        -0.348  -0.380  -0.370  -0.185  -0.216  -0.214  -0.419  -0.461  -0.440
141   P         0.865   0.813   0.793   1.129   1.039   1.013   0.784   0.691   0.642
142   T        -0.348  -0.299  -0.344  -0.234  -0.049  -0.230  -0.419  -0.350  -0.404
143   A        -0.348  -0.338  -0.354  -0.174  -0.165  -0.188  -0.419  -0.405  -0.417
144   P        -0.348  -0.382  -0.373  -0.174  -0.239  -0.225  -0.419  -0.463  -0.444
145   V        -0.348  -0.344  -0.358  -0.277  -0.275  -0.285  -0.419  -0.410  -0.422
146   T        -0.348  -0.338  -0.354  -0.343  -0.340  -0.359  -0.419  -0.405  -0.417
147   K         2.293   2.309   2.382   2.138   2.158   2.275   2.588   2.612   2.732
148   L         0.865   0.813   0.793   0.569   0.465   0.450   0.784   0.691   0.642
149   K         0.865   0.813   0.793   0.729   0.645   0.620   0.784   0.691   0.642
150   K         0.865   0.813   0.793   0.745   0.664   0.640   0.784   0.691   0.642
151   K        -1.229  -1.222  -1.198  -1.180  -1.153  -1.126  -1.020  -1.010  -0.964
152   T         0.865   0.813   0.793   0.929   0.850   0.830   0.784   0.691   0.642
153   K         0.865   0.873   0.811   0.581   0.583   0.460   0.784   0.796   0.675
154   T         0.865   0.813   0.793   0.929   0.850   0.830   0.784   0.691   0.642
155   Y         0.865   0.813   0.793   1.062   0.973   0.946   0.784   0.691   0.642
156   A        -0.348  -0.382  -0.373  -0.446  -0.518  -0.505  -0.419  -0.463  -0.444
157   D        -1.229  -1.222  -1.198  -1.150  -1.132  -1.095  -1.020  -1.010  -0.964
158   K         0.865   0.813   0.793   0.681   0.592   0.556   0.784   0.691   0.642
159   K         2.293   2.309   2.382   2.138   2.158   2.275   2.588   2.612   2.732
160   A         0.865   0.873   0.811   0.844   0.849   0.736   0.784   0.796   0.675
161   S        -0.348  -0.299  -0.344  -0.366  -0.283  -0.362  -0.419  -0.350  -0.404
162   K        -0.348  -0.344  -0.358  -0.499  -0.445  -0.507  -0.419  -0.410  -0.422
163   N        -1.229  -1.222  -1.198  -1.086  -1.084  -1.029  -1.020  -1.010  -0.964
164   K        -0.348  -0.380  -0.370  -0.552  -0.601  -0.586  -0.419  -0.461  -0.440
165   D         0.865   0.813   0.793   0.870   0.791   0.745   0.784   0.691   0.642
166   G        -1.229  -1.222  -1.198  -1.115  -1.099  -1.059  -1.020  -1.010  -0.964
167   S        -1.229  -1.222  -1.198  -1.042  -1.016  -0.984  -1.020  -1.010  -0.964
168   T        -0.348  -0.380  -0.370  -0.495  -0.548  -0.547  -0.419  -0.461  -0.440
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   A         0.865   0.876   0.813   0.844   0.854   0.740   0.784   0.801   0.678
173   Q        -1.229  -1.222  -1.198  -1.140  -1.080  -1.085  -1.020  -1.010  -0.964
174   F        -0.348  -0.380  -0.370  -0.265  -0.332  -0.324  -0.419  -0.461  -0.440
175   E         2.293   2.309   2.382   2.360   2.390   2.502   2.588   2.612   2.732
176   E         0.865   0.876   0.813   0.906   0.933   0.818   0.784   0.801   0.678
177   D        -0.348  -0.380  -0.370  -0.335  -0.387  -0.367  -0.419  -0.461  -0.440
178   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   E         0.676   0.667   0.674   0.531   0.504   0.509   0.450   0.429   0.423
180   V         0.676   0.675   0.677   0.536   0.521   0.519   0.450   0.444   0.429
181   K        -0.498  -0.492  -0.455  -0.821  -0.810  -0.758  -0.619  -0.610  -0.553
182   E        -1.229  -1.222  -1.198  -0.951  -0.871  -0.891  -1.020  -1.010  -0.964
183   V        -0.348  -0.297  -0.342  -0.406  -0.330  -0.384  -0.419  -0.348  -0.402
184   S         0.532   0.541   0.592   0.261   0.264   0.351   0.182   0.194   0.268
185   W         0.532   0.541   0.592   0.734   0.751   0.836   0.182   0.194   0.268
186   F        -0.348  -0.382  -0.373  -0.296  -0.371  -0.366  -0.419  -0.463  -0.444
187   Q         0.865   0.876   0.813   1.044   1.176   0.959   0.784   0.801   0.678
188   K         2.293   2.309   2.382   2.138   2.158   2.275   2.588   2.612   2.732
189   N         2.293   2.309   2.382   2.450   2.467   2.595   2.588   2.612   2.732
190   W         2.293   2.309   2.382   2.721   2.750   2.873   2.588   2.612   2.732
191   K         0.865   0.813   0.793   0.790   0.716   0.699   0.784   0.691   0.642
192   M        -0.348  -0.297  -0.342  -0.212  -0.136  -0.202  -0.419  -0.348  -0.402
193   L        -0.348  -0.297  -0.342  -0.382  -0.291  -0.376  -0.419  -0.348  -0.402
194   L         0.532   0.543   0.594   0.068   0.082   0.170   0.182   0.199   0.272
195   L        -0.348  -0.338  -0.354  -0.362  -0.343  -0.381  -0.419  -0.405  -0.417
196   G         0.865   0.813   0.793   1.067   1.012   0.967   0.784   0.691   0.642
197   L         0.865   0.876   0.813   0.640   0.636   0.573   0.784   0.801   0.678
198   L         2.293   2.309   2.382   2.005   2.005   2.139   2.588   2.612   2.732
199   I         0.865   0.873   0.811   0.967   0.970   0.878   0.784   0.796   0.675
200   Y         0.865   0.813   0.793   1.129   1.053   1.034   0.784   0.691   0.642
201   N        -0.348  -0.382  -0.373  -0.185  -0.239  -0.219  -0.419  -0.463  -0.444
202   F        -0.348  -0.380  -0.370  -0.319  -0.389  -0.386  -0.419  -0.461  -0.440
203   V        -0.348  -0.297  -0.342  -0.637  -0.586  -0.624  -0.419  -0.348  -0.402
204   A        -0.348  -0.382  -0.373  -0.519  -0.617  -0.590  -0.419  -0.463  -0.444
205   G         0.865   0.873   0.811   0.990   1.024   0.898   0.784   0.796   0.675
206   S        -1.229  -1.222  -1.198  -1.056  -1.031  -0.999  -1.020  -1.010  -0.964
207   A        -0.348  -0.338  -0.354  -0.394  -0.389  -0.406  -0.419  -0.405  -0.417
208   K         0.865   0.873   0.811   0.745   0.794   0.668   0.784   0.796   0.675
209   K         0.865   0.876   0.813   0.687   0.697   0.598   0.784   0.801   0.678
210   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q12025
Output conservation file - output/Q12025
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
