1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    M         2.081   2.084   2.205   2.519   2.524   2.733   2.376   2.383   2.594
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    K         0.803   0.818   0.900   0.640   0.674   0.781   0.422   0.453   0.542
33    F         0.994   1.029   1.012   0.603   0.653   0.641   0.813   0.879   0.780
34    T         0.341   0.313   0.277   0.406   0.350   0.288   0.162   0.113   0.050
35    P        -0.263  -0.251  -0.316  -0.135  -0.111  -0.221  -0.359  -0.337  -0.410
36    S        -1.267  -1.254  -1.206  -1.120  -1.104  -1.033  -1.011  -1.000  -0.912
37    I        -1.602  -1.599  -1.525  -1.508  -1.493  -1.411  -1.141  -1.139  -1.032
38    V        -0.010  -0.013   0.094  -0.467  -0.480  -0.352  -0.359  -0.363  -0.225
39    I        -0.932  -0.911  -0.845  -1.365  -1.347  -1.237  -0.881  -0.863  -0.760
40    D        -0.263  -0.280  -0.310  -0.240  -0.271  -0.320  -0.359  -0.383  -0.407
41    A         0.659   0.658   0.430   0.965   0.964   0.621   0.683   0.681   0.309
42    P         0.659   0.634   0.448   0.968   0.934   0.606   0.683   0.644   0.338
43    Q         0.007   0.039  -0.193   0.298   0.343  -0.018   0.031   0.074  -0.239
44    Y         0.341   0.330   0.274   0.652   0.633   0.537   0.162   0.145   0.046
45    Y        -0.010   0.004   0.116  -0.480  -0.466  -0.296  -0.359  -0.341  -0.196
46    V        -0.263  -0.256  -0.324  -0.241  -0.221  -0.329  -0.359  -0.343  -0.421
47    D         0.803   0.818   0.900   0.755   0.787   0.895   0.422   0.453   0.542
48    H        -0.471  -0.494  -0.423  -0.676  -0.719  -0.654  -0.620  -0.643  -0.544
49    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    V        -0.471  -0.453  -0.410  -0.512  -0.485  -0.404  -0.620  -0.604  -0.530
56    D        -0.471  -0.468  -0.401  -0.561  -0.555  -0.446  -0.620  -0.616  -0.521
57    K        -0.806  -0.822  -0.819  -0.930  -0.952  -0.995  -0.750  -0.767  -0.731
58    C        -0.471  -0.462  -0.414  -0.449  -0.438  -0.346  -0.620  -0.607  -0.532
59    V         0.198   0.215   0.203  -0.325  -0.306  -0.294  -0.099  -0.073  -0.077
60    I        -0.471  -0.494  -0.423  -0.906  -0.950  -0.855  -0.620  -0.643  -0.544
61    L         2.081   2.084   2.205   1.767   1.770   1.977   2.376   2.383   2.594
62    R         2.081   2.084   2.205   2.289   2.293   2.501   2.376   2.383   2.594
63    D        -0.806  -0.815  -0.794  -0.616  -0.627  -0.574  -0.750  -0.761  -0.706
64    L         0.007  -0.000  -0.197  -0.147  -0.157  -0.378   0.031   0.023  -0.245
65    Q        -0.598  -0.589  -0.686  -0.230  -0.217  -0.389  -0.490  -0.479  -0.579
66    L         0.994   1.029   1.012   0.822   0.890   0.774   0.813   0.879   0.780
67    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    S        -0.598  -0.559  -0.734  -0.206  -0.146  -0.426  -0.490  -0.444  -0.633
73    M        -1.602  -1.620  -1.531  -1.411  -1.451  -1.357  -1.141  -1.155  -1.036
74    P        -0.471  -0.462  -0.414  -0.831  -0.820  -0.757  -0.620  -0.607  -0.532
75    S         0.007   0.049  -0.225   0.215   0.280  -0.134   0.031   0.089  -0.283
76    S         0.803   0.818   0.900   0.628   0.656   0.775   0.422   0.453   0.542
77    L         2.081   2.084   2.205   1.767   1.770   1.977   2.376   2.383   2.594
78    K        -0.598  -0.559  -0.734  -0.273  -0.210  -0.538  -0.490  -0.444  -0.633
79    H        -0.471  -0.462  -0.414  -0.444  -0.431  -0.351  -0.620  -0.607  -0.532
80    L         0.198   0.201   0.215  -0.302  -0.297  -0.241  -0.099  -0.100  -0.062
81    T        -1.679  -1.675  -1.552  -1.505  -1.509  -1.316  -1.197  -1.195  -1.051
82    K        -0.471  -0.455  -0.406  -0.546  -0.515  -0.438  -0.620  -0.599  -0.526
83    P        -1.141  -1.176  -1.149  -0.806  -0.856  -0.837  -0.881  -0.915  -0.859
84    T        -0.471  -0.462  -0.413  -0.168  -0.145  -0.051  -0.620  -0.607  -0.532
85    H        -1.267  -1.284  -1.214  -1.037  -1.067  -0.971  -1.011  -1.024  -0.918
86    I        -0.471  -0.481  -0.397  -0.549  -0.555  -0.424  -0.620  -0.626  -0.513
87    L         0.742   0.744   0.867   0.109   0.109   0.307   0.292   0.294   0.468
88    D         2.081   2.084   2.205   2.276   2.280   2.488   2.376   2.383   2.594
89    L         0.341   0.336   0.275   0.030   0.022  -0.011   0.162   0.154   0.048
90    T         0.994   0.976   0.988   1.076   1.040   1.032   0.813   0.775   0.729
91    N         0.742   0.744   0.867   0.479   0.483   0.681   0.292   0.296   0.468
92    N         2.081   2.084   2.205   2.230   2.233   2.442   2.376   2.383   2.594
93    D         0.994   0.970   0.988   1.000   0.955   0.945   0.813   0.765   0.730
94    L         0.803   0.794   0.901   0.169   0.149   0.324   0.422   0.401   0.542
95    I        -0.471  -0.473  -0.405  -0.561  -0.569  -0.443  -0.620  -0.625  -0.524
96    M        -1.267  -1.268  -1.206  -0.919  -0.920  -0.819  -1.011  -1.011  -0.913
97    I        -0.598  -0.590  -0.722  -0.791  -0.776  -0.919  -0.490  -0.481  -0.619
98    P         0.198   0.202   0.208   0.288   0.300   0.324  -0.099  -0.088  -0.070
99    D        -0.263  -0.274  -0.315  -0.217  -0.223  -0.273  -0.359  -0.365  -0.409
100   L         0.198   0.210   0.201  -0.047  -0.010  -0.041  -0.099  -0.080  -0.080
101   S         0.007   0.049  -0.225   0.421   0.482   0.071   0.031   0.089  -0.283
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   R         0.007   0.024  -0.184   0.212   0.238  -0.120   0.031   0.054  -0.228
104   R        -0.806  -0.815  -0.817  -0.914  -0.948  -0.921  -0.750  -0.762  -0.730
105   D        -1.267  -1.278  -1.207  -1.260  -1.275  -1.168  -1.011  -1.019  -0.913
106   D        -0.932  -0.947  -0.864  -1.004  -1.023  -0.885  -0.881  -0.892  -0.775
107   I         0.742   0.745   0.867   0.109   0.098   0.312   0.292   0.297   0.468
108   H        -0.932  -0.929  -0.851  -0.782  -0.779  -0.667  -0.881  -0.877  -0.764
109   T         0.659   0.658   0.421   1.003   1.000   0.678   0.683   0.680   0.294
110   L         1.353   1.349   1.199   1.078   1.072   0.872   1.464   1.458   1.158
111   L         2.081   2.084   2.205   1.767   1.770   1.977   2.376   2.383   2.594
112   L         0.659   0.642   0.431   0.455   0.433   0.168   0.683   0.657   0.310
113   G         0.198   0.204   0.229   0.242   0.246   0.304  -0.099  -0.095  -0.048
114   R        -0.010  -0.014   0.094  -0.276  -0.283  -0.119  -0.359  -0.364  -0.227
115   N         2.081   2.084   2.205   2.230   2.233   2.442   2.376   2.383   2.594
116   N         0.803   0.815   0.893   0.633   0.657   0.756   0.422   0.446   0.525
117   I         1.353   1.370   1.206   1.473   1.496   1.206   1.464   1.494   1.170
118   V        -1.141  -1.104  -1.154  -0.869  -0.811  -0.897  -0.881  -0.844  -0.863
119   E        -1.602  -1.590  -1.518  -1.253  -1.227  -1.135  -1.141  -1.132  -1.027
120   V         0.341   0.381   0.251   0.155   0.214  -0.067   0.162   0.217   0.008
121   D        -0.263  -0.280  -0.319  -0.213  -0.251  -0.298  -0.359  -0.386  -0.419
122   G        -0.806  -0.791  -0.810  -0.652  -0.630  -0.642  -0.750  -0.733  -0.721
123   R        -1.602  -1.593  -1.515  -1.468  -1.450  -1.342  -1.141  -1.134  -1.024
124   L         0.245   0.202   0.187  -0.245  -0.320  -0.349   0.042  -0.026  -0.081
125   L         0.542   0.510   0.379   0.260   0.212   0.030   0.505   0.454   0.227
126   P         1.288   1.255   1.169   1.630   1.583   1.468   1.355   1.297   1.099
127   -         0.043   0.041   0.128  -0.204  -0.199  -0.067  -0.292  -0.293  -0.180
128   -        -0.493  -0.482  -0.419  -0.591  -0.573  -0.479  -0.625  -0.611  -0.533
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   M        -0.598  -0.583  -0.693  -0.226  -0.208  -0.386  -0.490  -0.473  -0.587
131   N         0.072   0.063   0.140  -0.008  -0.024   0.086  -0.229  -0.244  -0.156
132   V         0.341   0.362   0.280  -0.109  -0.076  -0.196   0.162   0.196   0.056
133   Q        -0.806  -0.823  -0.780  -0.678  -0.700  -0.622  -0.750  -0.764  -0.694
134   N        -0.471  -0.474  -0.404  -0.574  -0.575  -0.476  -0.620  -0.622  -0.524
135   L         0.341   0.336   0.275  -0.126  -0.137  -0.219   0.162   0.153   0.048
136   T         0.072   0.079   0.150  -0.003   0.009   0.105  -0.229  -0.220  -0.139
137   L         1.353   1.348   1.206   1.107   1.100   0.936   1.464   1.457   1.170
138   S        -0.598  -0.599  -0.693  -0.300  -0.304  -0.457  -0.490  -0.492  -0.587
139   N        -0.806  -0.806  -0.795  -0.606  -0.608  -0.550  -0.750  -0.753  -0.706
140   N         2.081   2.084   2.205   2.230   2.233   2.442   2.376   2.383   2.594
141   S        -0.806  -0.799  -0.796  -0.679  -0.667  -0.641  -0.750  -0.745  -0.710
142   I         1.353   1.342   1.202   1.473   1.452   1.198   1.464   1.446   1.162
143   R        -1.937  -1.936  -1.810  -1.581  -1.577  -1.392  -1.271  -1.271  -1.127
144   R        -1.267  -1.267  -1.206  -1.264  -1.261  -1.156  -1.011  -1.011  -0.912
145   F         0.198   0.185   0.214  -0.047  -0.085  -0.052  -0.099  -0.118  -0.068
146   E        -0.806  -0.818  -0.791  -0.838  -0.846  -0.830  -0.750  -0.758  -0.701
147   D         0.007  -0.010  -0.174   0.244   0.219  -0.046   0.031   0.008  -0.215
148   L         1.288   1.253   1.159   0.965   0.914   0.777   1.355   1.294   1.078
149   Q        -1.141  -1.119  -1.138  -1.019  -0.984  -1.024  -0.881  -0.859  -0.848
150   R        -1.602  -1.601  -1.503  -1.269  -1.266  -1.123  -1.141  -1.140  -1.016
151   L         1.353   1.358   1.203   1.067   1.073   0.855   1.464   1.474   1.164
152   R        -1.937  -1.936  -1.810  -1.528  -1.524  -1.339  -1.271  -1.271  -1.127
153   R        -0.806  -0.810  -0.781  -0.683  -0.693  -0.627  -0.750  -0.757  -0.693
154   A        -0.471  -0.485  -0.408  -0.365  -0.392  -0.292  -0.620  -0.631  -0.528
155   P         0.659   0.618   0.442   1.023   0.966   0.689   0.683   0.621   0.328
156   R        -0.932  -0.930  -0.843  -0.991  -0.987  -0.840  -0.881  -0.878  -0.758
157   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   L         1.353   1.370   1.206   1.078   1.101   0.882   1.464   1.494   1.170
159   K        -0.806  -0.792  -0.811  -0.780  -0.750  -0.797  -0.750  -0.733  -0.722
160   N        -0.598  -0.605  -0.684  -0.367  -0.380  -0.493  -0.490  -0.499  -0.577
161   L         0.994   0.970   0.988   0.509   0.463   0.475   0.813   0.765   0.730
162   T        -0.806  -0.810  -0.774  -0.649  -0.650  -0.587  -0.750  -0.752  -0.688
163   L         0.659   0.642   0.431   0.489   0.466   0.225   0.683   0.657   0.310
164   I        -0.598  -0.620  -0.692  -0.522  -0.563  -0.721  -0.490  -0.516  -0.585
165   G         0.341   0.335   0.281   0.506   0.497   0.384   0.162   0.153   0.057
166   N         2.081   2.084   2.205   2.230   2.233   2.442   2.376   2.383   2.594
167   Q         0.659   0.694   0.425   1.046   1.092   0.699   0.683   0.734   0.301
168   V         0.803   0.807   0.891   0.660   0.670   0.778   0.422   0.431   0.521
169   C        -0.345  -0.374  -0.358  -0.109  -0.149  -0.112  -0.490  -0.518  -0.472
170   H        -1.141  -1.149  -1.148  -0.680  -0.689  -0.723  -0.881  -0.888  -0.858
171   L        -0.806  -0.831  -0.822  -1.150  -1.175  -1.089  -0.750  -0.774  -0.733
172   A        -0.932  -0.931  -0.853  -0.887  -0.878  -0.750  -0.881  -0.879  -0.765
173   N        -0.598  -0.629  -0.705  -0.366  -0.411  -0.525  -0.490  -0.526  -0.601
174   Y         2.081   2.084   2.205   2.544   2.548   2.759   2.376   2.383   2.594
175   R         2.081   2.084   2.205   2.289   2.293   2.501   2.376   2.383   2.594
176   E        -0.806  -0.810  -0.801  -0.628  -0.638  -0.682  -0.750  -0.754  -0.713
177   H        -0.806  -0.778  -0.788  -0.323  -0.290  -0.268  -0.750  -0.727  -0.699
178   V        -0.806  -0.828  -0.788  -0.857  -0.887  -0.844  -0.750  -0.768  -0.702
179   L         0.198   0.206   0.224  -0.259  -0.227  -0.206  -0.099  -0.083  -0.051
180   R        -0.263  -0.238  -0.318   0.104   0.132  -0.019  -0.359  -0.337  -0.420
181   L         0.007  -0.041  -0.191  -0.297  -0.371  -0.607   0.031  -0.033  -0.237
182   V        -0.471  -0.480  -0.405  -0.561  -0.581  -0.473  -0.620  -0.624  -0.525
183   P         2.081   2.084   2.205   2.399   2.404   2.612   2.376   2.383   2.594
184   H        -0.263  -0.236  -0.294  -0.063  -0.030  -0.091  -0.359  -0.327  -0.390
185   L         1.353   1.366   1.210   1.078   1.095   0.890   1.464   1.486   1.179
186   E        -0.471  -0.485  -0.422  -0.586  -0.599  -0.479  -0.620  -0.635  -0.544
187   T        -0.598  -0.598  -0.696  -0.264  -0.261  -0.408  -0.490  -0.491  -0.590
188   L         2.081   2.084   2.205   1.767   1.770   1.977   2.376   2.383   2.594
189   D         2.081   2.084   2.205   2.276   2.280   2.488   2.376   2.383   2.594
190   F         1.353   1.366   1.210   1.835   1.852   1.666   1.464   1.486   1.179
191   Q        -0.806  -0.808  -0.786  -0.685  -0.683  -0.670  -0.750  -0.750  -0.699
192   N        -0.263  -0.240  -0.297  -0.386  -0.354  -0.496  -0.359  -0.341  -0.390
193   V         2.081   2.084   2.205   2.315   2.323   2.527   2.376   2.383   2.594
194   T        -0.345  -0.343  -0.339  -0.392  -0.387  -0.361  -0.490  -0.488  -0.452
195   A        -0.263  -0.232  -0.307  -0.087  -0.047  -0.178  -0.359  -0.326  -0.407
196   E        -0.345  -0.327  -0.319  -0.425  -0.399  -0.379  -0.490  -0.472  -0.432
197   E         2.081   2.084   2.205   2.210   2.218   2.422   2.376   2.383   2.594
198   R         0.659   0.669   0.440   0.827   0.839   0.429   0.683   0.697   0.324
199   K        -1.267  -1.274  -1.187  -1.535  -1.553  -1.394  -1.011  -1.016  -0.897
200   S        -1.267  -1.270  -1.200  -1.158  -1.163  -1.061  -1.011  -1.013  -0.907
201   A         0.659   0.658   0.428   0.959   0.956   0.606   0.683   0.681   0.305
202   M        -0.806  -0.776  -0.792  -0.776  -0.731  -0.731  -0.750  -0.720  -0.705
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   S        -0.471  -0.467  -0.408  -0.598  -0.589  -0.493  -0.620  -0.615  -0.528
227   F        -0.471  -0.459  -0.397  -0.772  -0.752  -0.614  -0.620  -0.612  -0.517
228   P         0.234   0.266   0.220   0.435   0.490   0.402  -0.006   0.044  -0.038
229   R         0.234   0.266   0.220   0.346   0.404   0.310  -0.006   0.044  -0.038
230   Q        -0.004   0.000   0.102  -0.153  -0.148   0.017  -0.346  -0.340  -0.213
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   A        -0.387  -0.389  -0.363  -0.407  -0.420  -0.375  -0.516  -0.524  -0.473
233   D         0.925   0.904   0.936   0.944   0.906   0.940   0.675   0.632   0.620
234   G        -0.914  -0.937  -0.851  -0.867  -0.909  -0.779  -0.857  -0.877  -0.761
235   D        -0.769  -0.732  -0.792  -0.545  -0.482  -0.609  -0.686  -0.645  -0.696
236   T        -0.387  -0.400  -0.356  -0.407  -0.423  -0.365  -0.516  -0.530  -0.466
237   L        -0.769  -0.732  -0.792  -0.828  -0.750  -0.916  -0.686  -0.645  -0.696
238   G        -0.769  -0.753  -0.793  -1.064  -1.050  -1.051  -0.686  -0.669  -0.696
239   P        -0.148  -0.100  -0.275   0.140   0.211  -0.053  -0.176  -0.112  -0.348
240   -        -1.029  -1.020  -0.903  -1.330  -1.300  -1.140  -0.959  -0.950  -0.808
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   V        -0.914  -0.889  -0.856  -0.932  -0.897  -0.821  -0.857  -0.834  -0.766
251   N         0.141   0.138   0.181  -0.021  -0.022   0.053  -0.176  -0.178  -0.112
252   T        -0.387  -0.402  -0.369  -0.396  -0.426  -0.380  -0.516  -0.538  -0.480
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   A        -0.806  -0.799  -0.782  -0.807  -0.787  -0.763  -0.750  -0.739  -0.691
259   I        -0.806  -0.795  -0.805  -0.627  -0.600  -0.651  -0.750  -0.736  -0.718
260   R        -0.806  -0.786  -0.803  -0.756  -0.721  -0.745  -0.750  -0.729  -0.717
261   D        -0.806  -0.792  -0.783  -1.008  -0.987  -0.992  -0.750  -0.737  -0.696
262   N        -1.602  -1.602  -1.508  -1.352  -1.349  -1.223  -1.141  -1.141  -1.019
263   G        -0.531  -0.537  -0.436  -0.593  -0.602  -0.438  -0.686  -0.691  -0.559
264   S        -0.387  -0.385  -0.356  -0.579  -0.585  -0.561  -0.516  -0.510  -0.466
265   R        -0.387  -0.419  -0.388  -0.404  -0.453  -0.413  -0.516  -0.553  -0.503
266   D        -0.148  -0.189  -0.276   0.026  -0.038  -0.188  -0.176  -0.231  -0.349
267   K        -0.387  -0.412  -0.393  -0.488  -0.528  -0.502  -0.516  -0.546  -0.507
268   T        -0.914  -0.920  -0.845  -0.676  -0.676  -0.558  -0.857  -0.861  -0.755
269   M        -1.296  -1.311  -1.226  -1.201  -1.236  -1.148  -1.027  -1.040  -0.926
270   E        -0.148  -0.164  -0.261  -0.021  -0.046  -0.209  -0.176  -0.196  -0.330
271   I        -1.679  -1.677  -1.552  -1.804  -1.801  -1.617  -1.197  -1.195  -1.051
272   M        -0.493  -0.523  -0.441  -0.584  -0.651  -0.585  -0.625  -0.663  -0.559
273   N         0.043   0.020   0.130  -0.064  -0.096   0.082  -0.292  -0.320  -0.175
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   V        -0.598  -0.625  -0.712  -0.318  -0.360  -0.507  -0.490  -0.522  -0.608
280   V        -0.263  -0.290  -0.319  -0.122  -0.161  -0.209  -0.359  -0.394  -0.419
281   S        -1.141  -1.133  -1.138  -1.044  -1.025  -1.064  -0.881  -0.873  -0.848
282   K         0.659   0.612   0.436   0.867   0.801   0.524   0.683   0.612   0.317
283   M         0.803   0.815   0.892   0.338   0.352   0.505   0.422   0.446   0.523
284   T         0.659   0.619   0.439   0.949   0.890   0.616   0.683   0.622   0.323
285   V        -0.806  -0.813  -0.786  -0.789  -0.795  -0.741  -0.750  -0.758  -0.697
286   E         0.341   0.312   0.274   0.307   0.271   0.184   0.162   0.123   0.040
287   R        -0.806  -0.787  -0.792  -0.843  -0.815  -0.820  -0.750  -0.735  -0.705
288   R         0.742   0.744   0.867   0.499   0.504   0.701   0.292   0.295   0.469
289   N        -0.932  -0.935  -0.849  -1.000  -0.998  -0.861  -0.881  -0.882  -0.763
290   E         0.198   0.201   0.224   0.046   0.053   0.112  -0.099  -0.097  -0.054
291   L         0.803   0.803   0.884   0.169   0.165   0.302   0.422   0.422   0.505
292   K        -0.471  -0.471  -0.398  -0.836  -0.839  -0.702  -0.620  -0.621  -0.516
293   K        -0.263  -0.243  -0.301  -0.279  -0.237  -0.334  -0.359  -0.330  -0.397
294   Q        -1.141  -1.167  -1.179  -1.030  -1.075  -1.195  -0.881  -0.906  -0.885
295   L         0.994   0.995   0.998   0.509   0.506   0.493   0.813   0.813   0.751
296   A        -0.471  -0.462  -0.414  -0.589  -0.568  -0.482  -0.620  -0.607  -0.532
297   E        -0.263  -0.226  -0.298  -0.283  -0.228  -0.348  -0.359  -0.317  -0.389
298   A         2.081   2.084   2.205   2.328   2.332   2.541   2.376   2.383   2.594
299   T         0.072   0.075   0.133  -0.020  -0.016   0.054  -0.229  -0.225  -0.165
300   S         0.994   0.971   0.973   1.076   1.032   1.003   0.813   0.765   0.698
301   L        -0.345  -0.339  -0.336  -0.740  -0.723  -0.676  -0.490  -0.483  -0.450
302   E         0.007  -0.041  -0.191   0.207   0.141  -0.092   0.031  -0.033  -0.237
303   E         1.353   1.348   1.206   1.517   1.515   1.313   1.464   1.457   1.170
304   I         1.353   1.370   1.206   1.473   1.496   1.206   1.464   1.494   1.170
305   A         0.007   0.039  -0.181   0.160   0.210  -0.148   0.031   0.075  -0.224
306   R         1.353   1.316   1.214   1.587   1.536   1.387   1.464   1.402   1.185
307   L         0.803   0.793   0.901   0.169   0.149   0.325   0.422   0.401   0.543
308   E         2.081   2.084   2.205   2.210   2.218   2.422   2.376   2.383   2.594
309   K        -0.932  -0.932  -0.845  -0.991  -0.985  -0.854  -0.881  -0.879  -0.759
310   L        -0.471  -0.478  -0.422  -0.825  -0.821  -0.687  -0.620  -0.630  -0.544
311   L         2.081   2.084   2.205   1.767   1.770   1.977   2.376   2.383   2.594
312   S        -1.267  -1.255  -1.199  -1.312  -1.298  -1.223  -1.011  -1.001  -0.907
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   G         2.081   2.084   2.205   2.427   2.432   2.641   2.376   2.383   2.594
315   G        -1.296  -1.320  -1.231  -1.073  -1.115  -0.992  -1.027  -1.048  -0.930
316   V        -0.148  -0.189  -0.276  -0.032  -0.096  -0.298  -0.176  -0.231  -0.349
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q08963
Output conservation file - output/Q08963
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
